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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for RXRA_NR2F6_NR2C2

Z-value: 1.31

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Transcription factors associated with RXRA_NR2F6_NR2C2

Gene Symbol Gene ID Gene Info
ENSG00000186350.8 retinoid X receptor alpha
ENSG00000160113.5 nuclear receptor subfamily 2 group F member 6
ENSG00000177463.11 nuclear receptor subfamily 2 group C member 2

Activity-expression correlation:

Activity profile of RXRA_NR2F6_NR2C2 motif

Sorted Z-values of RXRA_NR2F6_NR2C2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_65613340 7.83 ENST00000546702.1
adenylate kinase 4
chr19_+_10197463 6.52 ENST00000590378.1
ENST00000397881.3
chromosome 19 open reading frame 66
chr2_+_219433588 6.39 ENST00000295701.5
RCD1 required for cell differentiation1 homolog (S. pombe)
chr6_-_160148356 4.19 ENST00000401980.3
ENST00000545162.1
superoxide dismutase 2, mitochondrial
chr19_+_10196981 4.17 ENST00000591813.1
chromosome 19 open reading frame 66
chr12_+_132413739 4.17 ENST00000443358.2
pseudouridylate synthase 1
chr6_-_160147925 4.17 ENST00000535561.1
superoxide dismutase 2, mitochondrial
chr12_+_132413798 3.46 ENST00000440818.2
ENST00000542167.2
ENST00000538037.1
ENST00000456665.2
pseudouridylate synthase 1
chr1_+_65613513 3.32 ENST00000395334.2
adenylate kinase 4
chr1_+_65613852 3.22 ENST00000327299.7
adenylate kinase 4
chr12_+_132413765 3.19 ENST00000376649.3
ENST00000322060.5
pseudouridylate synthase 1
chr2_+_219433281 3.15 ENST00000273064.6
ENST00000509807.2
ENST00000542068.1
RCD1 required for cell differentiation1 homolog (S. pombe)
chr4_-_681114 2.90 ENST00000503156.1
major facilitator superfamily domain containing 7
chr19_+_45394477 2.90 ENST00000252487.5
ENST00000405636.2
ENST00000592434.1
ENST00000426677.2
ENST00000589649.1
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr7_+_86274145 2.77 ENST00000439827.1
ENST00000394720.2
ENST00000421579.1
glutamate receptor, metabotropic 3
chr3_+_9691117 2.63 ENST00000353332.5
ENST00000420925.1
ENST00000296003.4
ENST00000351233.5
myotubularin related protein 14
chr12_-_56236734 2.54 ENST00000548629.1
matrix metallopeptidase 19
chr2_+_73441350 2.44 ENST00000389501.4
SMYD family member 5
chr1_-_161102367 2.22 ENST00000464113.1
death effector domain containing
chr14_-_91720224 2.14 ENST00000238699.3
ENST00000531499.2
G protein-coupled receptor 68
chr1_+_113217345 2.11 ENST00000357443.2
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr1_+_113217309 2.08 ENST00000544796.1
ENST00000369644.1
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr1_+_113217043 2.05 ENST00000413052.2
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr5_+_14664762 2.05 ENST00000284274.4
family with sequence similarity 105, member B
chr11_-_61658853 2.01 ENST00000525588.1
ENST00000540820.1
fatty acid desaturase 3
chr11_-_61659006 1.96 ENST00000278829.2
fatty acid desaturase 3
chr1_+_113217073 1.95 ENST00000369645.1
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr20_+_44486246 1.90 ENST00000255152.2
ENST00000454862.2
zinc finger, SWIM-type containing 3
chr12_-_56236690 1.86 ENST00000322569.4
matrix metallopeptidase 19
chr19_+_50919056 1.85 ENST00000599632.1
CTD-2545M3.6
chr21_+_27011899 1.85 ENST00000425221.2
junctional adhesion molecule 2
chr1_+_65613217 1.85 ENST00000545314.1
adenylate kinase 4
chr19_+_39616410 1.84 ENST00000602004.1
ENST00000599470.1
ENST00000321944.4
ENST00000593480.1
ENST00000358301.3
ENST00000593690.1
ENST00000599386.1
p21 protein (Cdc42/Rac)-activated kinase 4
chrX_+_38211777 1.83 ENST00000039007.4
ornithine carbamoyltransferase
chr1_-_161102421 1.80 ENST00000490843.2
ENST00000368006.3
ENST00000392188.1
ENST00000545495.1
death effector domain containing
chr7_-_139763521 1.78 ENST00000263549.3
poly (ADP-ribose) polymerase family, member 12
chr1_-_43855444 1.73 ENST00000372455.4
mediator complex subunit 8
chr8_+_145582633 1.72 ENST00000540505.1
solute carrier family 52 (riboflavin transporter), member 2
chr6_+_160148593 1.71 ENST00000337387.4
Wilms tumor 1 associated protein
chr2_+_26568965 1.70 ENST00000260585.7
ENST00000447170.1
ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)
chr12_-_57522813 1.69 ENST00000556155.1
signal transducer and activator of transcription 6, interleukin-4 induced
chr3_+_37284824 1.69 ENST00000431105.1
golgin A4
chr6_-_31926629 1.69 ENST00000375425.5
ENST00000426722.1
ENST00000441998.1
ENST00000444811.2
ENST00000375429.3
negative elongation factor complex member E
chr4_-_7069760 1.67 ENST00000264954.4
GrpE-like 1, mitochondrial (E. coli)
chr2_+_74757050 1.66 ENST00000352222.3
ENST00000437202.1
HtrA serine peptidase 2
chr13_-_53313905 1.65 ENST00000377962.3
ENST00000448904.2
leukocyte cell derived chemotaxin 1
chr20_+_32399093 1.59 ENST00000217402.2
charged multivesicular body protein 4B
chr2_-_219134822 1.56 ENST00000444053.1
ENST00000248450.4
angio-associated, migratory cell protein
chr17_-_74497432 1.56 ENST00000590288.1
ENST00000313080.4
ENST00000592123.1
ENST00000591255.1
ENST00000585989.1
ENST00000591697.1
ENST00000389760.4
rhomboid 5 homolog 2 (Drosophila)
chr4_+_95972822 1.50 ENST00000509540.1
ENST00000440890.2
bone morphogenetic protein receptor, type IB
chr1_-_43855479 1.49 ENST00000290663.6
ENST00000372457.4
mediator complex subunit 8
chr17_+_56270084 1.46 ENST00000225371.5
eosinophil peroxidase
chr17_-_2614927 1.45 ENST00000435359.1
clustered mitochondria (cluA/CLU1) homolog
chr2_-_200820459 1.39 ENST00000354611.4
tRNA-yW synthesizing protein 5
chr16_+_57653989 1.37 ENST00000567835.1
ENST00000569372.1
ENST00000563548.1
ENST00000562003.1
G protein-coupled receptor 56
chr19_+_1205740 1.37 ENST00000326873.7
serine/threonine kinase 11
chr12_+_27485889 1.37 ENST00000311001.5
ENST00000261178.5
ENST00000266503.5
aryl hydrocarbon receptor nuclear translocator-like 2
chr11_-_123756334 1.36 ENST00000528595.1
ENST00000375026.2
transmembrane protein 225
chr1_+_165864800 1.35 ENST00000469256.2
uridine-cytidine kinase 2
chr12_-_51420128 1.34 ENST00000262051.7
ENST00000547732.1
ENST00000262052.5
ENST00000546488.1
ENST00000550714.1
ENST00000548193.1
ENST00000547579.1
ENST00000546743.1
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr16_+_57653854 1.34 ENST00000568908.1
ENST00000568909.1
ENST00000566778.1
ENST00000561988.1
G protein-coupled receptor 56
chr12_+_27485785 1.34 ENST00000544915.1
aryl hydrocarbon receptor nuclear translocator-like 2
chr12_+_27485823 1.31 ENST00000395901.2
ENST00000546179.1
aryl hydrocarbon receptor nuclear translocator-like 2
chr7_-_108096765 1.26 ENST00000379024.4
ENST00000351718.4
neuronal cell adhesion molecule
chr17_+_4853442 1.25 ENST00000522301.1
enolase 3 (beta, muscle)
chr1_-_151300160 1.24 ENST00000368874.4
phosphatidylinositol 4-kinase, catalytic, beta
chr12_-_54779511 1.24 ENST00000551109.1
ENST00000546970.1
zinc finger protein 385A
chr1_+_165864821 1.23 ENST00000470820.1
uridine-cytidine kinase 2
chr16_+_57673430 1.23 ENST00000540164.2
ENST00000568531.1
G protein-coupled receptor 56
chr20_+_43160409 1.22 ENST00000372894.3
ENST00000372892.3
ENST00000372891.3
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr9_+_74764278 1.21 ENST00000238018.4
ENST00000376989.3
guanine deaminase
chr17_-_4852243 1.18 ENST00000225655.5
profilin 1
chr14_+_32546274 1.16 ENST00000396582.2
Rho GTPase activating protein 5
chr2_+_162016827 1.15 ENST00000429217.1
ENST00000406287.1
ENST00000402568.1
TRAF family member-associated NFKB activator
chr2_+_162016804 1.15 ENST00000392749.2
ENST00000440506.1
TRAF family member-associated NFKB activator
chr1_+_43855560 1.14 ENST00000562955.1
seizure threshold 2 homolog (mouse)
chr2_-_219134343 1.14 ENST00000447885.1
ENST00000420660.1
angio-associated, migratory cell protein
chr1_-_155271213 1.13 ENST00000342741.4
pyruvate kinase, liver and RBC
chr9_-_139137648 1.13 ENST00000358701.5
quiescin Q6 sulfhydryl oxidase 2
chr11_-_45939565 1.13 ENST00000525192.1
ENST00000378750.5
peroxisomal biogenesis factor 16
chr1_-_151300126 1.12 ENST00000368875.2
ENST00000529142.1
phosphatidylinositol 4-kinase, catalytic, beta
chr9_-_16705069 1.11 ENST00000471301.2
basonuclin 2
chr19_-_633576 1.11 ENST00000588649.2
polymerase (RNA) mitochondrial (DNA directed)
chr20_+_43160458 1.11 ENST00000372889.1
ENST00000372887.1
ENST00000372882.3
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr9_-_100881466 1.10 ENST00000341469.2
ENST00000342043.3
ENST00000375098.3
tripartite motif containing 14
chr6_+_33172407 1.09 ENST00000374662.3
hydroxysteroid (17-beta) dehydrogenase 8
chr18_-_70210764 1.08 ENST00000585159.1
ENST00000584764.1
cerebellin 2 precursor
chr7_-_108096822 1.07 ENST00000379028.3
ENST00000413765.2
ENST00000379022.4
neuronal cell adhesion molecule
chr3_+_37284668 1.07 ENST00000361924.2
ENST00000444882.1
ENST00000356847.4
ENST00000450863.2
ENST00000429018.1
golgin A4
chr16_-_4401284 1.06 ENST00000318059.3
presequence translocase-associated motor 16 homolog (S. cerevisiae)
chr1_+_50574585 1.06 ENST00000371824.1
ENST00000371823.4
ELAV like neuron-specific RNA binding protein 4
chr15_-_82555000 1.05 ENST00000557844.1
ENST00000359445.3
ENST00000268206.7
elongation factor Tu GTP binding domain containing 1
chr1_-_151299842 1.03 ENST00000438243.2
ENST00000489223.2
ENST00000368873.1
ENST00000430800.1
ENST00000368872.1
phosphatidylinositol 4-kinase, catalytic, beta
chr16_-_67970990 1.02 ENST00000358514.4
proteasome (prosome, macropain) subunit, beta type, 10
chr2_+_219283815 1.01 ENST00000248444.5
ENST00000454069.1
ENST00000392114.2
villin 1
chr14_+_23352374 1.00 ENST00000267396.4
ENST00000536884.1
RAS (RAD and GEM)-like GTP binding 2
chr3_-_113465065 0.99 ENST00000497255.1
ENST00000478020.1
ENST00000240922.3
ENST00000493900.1
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr19_-_46418033 0.98 ENST00000341294.2
nanos homolog 2 (Drosophila)
chrX_-_108868390 0.98 ENST00000372101.2
KCNE1-like
chr5_+_98109322 0.98 ENST00000513185.1
repulsive guidance molecule family member b
chr2_-_208031542 0.96 ENST00000423015.1
Kruppel-like factor 7 (ubiquitous)
chr11_-_45939374 0.95 ENST00000533151.1
ENST00000241041.3
peroxisomal biogenesis factor 16
chr16_+_2255841 0.95 ENST00000301725.7
MTOR associated protein, LST8 homolog (S. cerevisiae)
chr6_+_31895467 0.92 ENST00000556679.1
ENST00000456570.1
complement factor B
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr8_+_22224811 0.92 ENST00000381237.1
solute carrier family 39 (zinc transporter), member 14
chr5_+_96212185 0.91 ENST00000379904.4
endoplasmic reticulum aminopeptidase 2
chr16_-_67190152 0.90 ENST00000486556.1
TNFRSF1A-associated via death domain
chr19_+_489140 0.88 ENST00000587541.1
mucosal vascular addressin cell adhesion molecule 1
chr16_-_4401258 0.88 ENST00000577031.1
presequence translocase-associated motor 16 homolog (S. cerevisiae)
chr2_+_27719697 0.88 ENST00000264717.2
ENST00000424318.2
glucokinase (hexokinase 4) regulator
chr1_-_156722015 0.88 ENST00000368209.5
hepatoma-derived growth factor
chr19_-_49371711 0.87 ENST00000355496.5
ENST00000263265.6
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
chr14_-_101295407 0.87 ENST00000596284.1
AL117190.2
chr16_+_2255710 0.87 ENST00000397124.1
ENST00000565250.1
MTOR associated protein, LST8 homolog (S. cerevisiae)
chr19_-_10687948 0.86 ENST00000592285.1
adaptor-related protein complex 1, mu 2 subunit
chr3_-_119396193 0.86 ENST00000484810.1
ENST00000497116.1
ENST00000261070.2
COX17 cytochrome c oxidase copper chaperone
chr1_-_156721389 0.85 ENST00000537739.1
hepatoma-derived growth factor
chr3_-_150264272 0.85 ENST00000491660.1
ENST00000487153.1
ENST00000239944.2
stress-associated endoplasmic reticulum protein 1
chr1_+_43855545 0.83 ENST00000372450.4
ENST00000310739.4
seizure threshold 2 homolog (mouse)
chr7_+_65670186 0.82 ENST00000304842.5
ENST00000442120.1
tyrosylprotein sulfotransferase 1
chr2_+_162016916 0.82 ENST00000405852.1
TRAF family member-associated NFKB activator
chr7_-_143105941 0.82 ENST00000275815.3
EPH receptor A1
chr5_+_156712372 0.82 ENST00000541131.1
cytoplasmic FMR1 interacting protein 2
chr19_+_49867181 0.81 ENST00000597546.1
dickkopf-like 1
chr1_-_156721502 0.81 ENST00000357325.5
hepatoma-derived growth factor
chr4_-_146859623 0.81 ENST00000379448.4
ENST00000513320.1
zinc finger protein 827
chr19_+_17420340 0.81 ENST00000359866.4
DET1 and DDB1 associated 1
chr16_+_30710462 0.81 ENST00000262518.4
ENST00000395059.2
ENST00000344771.4
Snf2-related CREBBP activator protein
chr4_+_24797085 0.81 ENST00000382120.3
superoxide dismutase 3, extracellular
chr17_+_79650962 0.80 ENST00000329138.4
hepatocyte growth factor-regulated tyrosine kinase substrate
chr11_-_3663502 0.80 ENST00000359918.4
ADP-ribosyltransferase 5
chr11_-_65430554 0.78 ENST00000308639.9
ENST00000406246.3
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr9_+_74526384 0.77 ENST00000334731.2
ENST00000377031.3
chromosome 9 open reading frame 85
chr5_+_96211643 0.76 ENST00000437043.3
ENST00000510373.1
endoplasmic reticulum aminopeptidase 2
chr11_-_65430251 0.76 ENST00000534283.1
ENST00000527749.1
ENST00000533187.1
ENST00000525693.1
ENST00000534558.1
ENST00000532879.1
ENST00000532999.1
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr2_+_210636697 0.75 ENST00000439458.1
ENST00000272845.6
unc-80 homolog (C. elegans)
chr6_+_170190417 0.75 ENST00000420557.2
long intergenic non-protein coding RNA 574
chr19_-_51530916 0.74 ENST00000594768.1
kallikrein-related peptidase 11
chr18_-_11670159 0.74 ENST00000561598.1
RP11-677O4.2
chr19_+_35629702 0.72 ENST00000351325.4
FXYD domain containing ion transport regulator 1
chr19_+_39390587 0.72 ENST00000572515.1
ENST00000392079.3
ENST00000575359.1
ENST00000313582.5
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr14_-_24658053 0.72 ENST00000354464.6
importin 4
chr19_+_50145328 0.72 ENST00000360565.3
SR-related CTD-associated factor 1
chr4_-_120243545 0.71 ENST00000274024.3
fatty acid binding protein 2, intestinal
chr19_+_35630344 0.71 ENST00000455515.2
FXYD domain containing ion transport regulator 1
chr6_+_31637944 0.71 ENST00000375864.4
lymphocyte antigen 6 complex, locus G5B
chr2_-_28113217 0.70 ENST00000444339.2
ribokinase
chr19_+_35630022 0.70 ENST00000589209.1
FXYD domain containing ion transport regulator 1
chr12_+_7079944 0.69 ENST00000261406.6
EMG1 N1-specific pseudouridine methyltransferase
chr1_+_202317815 0.69 ENST00000608999.1
ENST00000336894.4
ENST00000480184.1
protein phosphatase 1, regulatory subunit 12B
chr19_-_10687983 0.69 ENST00000587069.1
adaptor-related protein complex 1, mu 2 subunit
chr17_-_1395954 0.69 ENST00000359786.5
myosin IC
chr5_+_34757309 0.69 ENST00000397449.1
retinoic acid induced 14
chr16_+_30075463 0.68 ENST00000562168.1
ENST00000569545.1
aldolase A, fructose-bisphosphate
chr6_+_31916733 0.68 ENST00000483004.1
complement factor B
chr2_+_120125245 0.68 ENST00000393103.2
diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
chr2_-_219433014 0.67 ENST00000418019.1
ENST00000454775.1
ENST00000338465.5
ENST00000415516.1
ENST00000258399.3
ubiquitin specific peptidase 37
chr1_+_156084461 0.67 ENST00000347559.2
ENST00000361308.4
ENST00000368300.4
ENST00000368299.3
lamin A/C
chr1_-_111743285 0.67 ENST00000357640.4
DENN/MADD domain containing 2D
chr16_+_30075783 0.66 ENST00000412304.2
aldolase A, fructose-bisphosphate
chr20_+_37590942 0.66 ENST00000373325.2
ENST00000252011.3
ENST00000373323.4
DEAH (Asp-Glu-Ala-His) box polypeptide 35
chr11_+_118443098 0.65 ENST00000392859.3
ENST00000359415.4
ENST00000534182.2
ENST00000264028.4
archain 1
chr19_+_35630628 0.64 ENST00000588715.1
ENST00000588607.1
FXYD domain containing ion transport regulator 1
chr12_+_113659234 0.63 ENST00000551096.1
ENST00000551099.1
ENST00000335509.6
ENST00000552897.1
ENST00000550785.1
ENST00000549279.1
two pore segment channel 1
chr22_+_38453378 0.63 ENST00000437453.1
ENST00000356976.3
protein interacting with PRKCA 1
chr15_+_43985084 0.63 ENST00000434505.1
ENST00000411750.1
creatine kinase, mitochondrial 1A
chr17_-_4852332 0.63 ENST00000572383.1
profilin 1
chr19_+_535835 0.63 ENST00000607527.1
ENST00000606065.1
cell division cycle 34
chr15_+_43885252 0.62 ENST00000453782.1
ENST00000300283.6
ENST00000437924.1
ENST00000450086.2
creatine kinase, mitochondrial 1B
chr17_+_7531281 0.62 ENST00000575729.1
ENST00000340624.5
sex hormone-binding globulin
chr17_+_41132564 0.61 ENST00000361677.1
ENST00000589705.1
RUN domain containing 1
chr16_+_30075595 0.61 ENST00000563060.2
aldolase A, fructose-bisphosphate
chr6_+_123100853 0.60 ENST00000356535.4
fatty acid binding protein 7, brain
chr17_+_53828381 0.60 ENST00000576183.1
phosphatidylcholine transfer protein
chr17_+_53828333 0.59 ENST00000268896.5
phosphatidylcholine transfer protein
chr12_+_96252706 0.59 ENST00000266735.5
ENST00000553192.1
ENST00000552085.1
small nuclear ribonucleoprotein polypeptide F
chr1_-_11107280 0.58 ENST00000400897.3
ENST00000400898.3
mannan-binding lectin serine peptidase 2
chr20_+_62369623 0.58 ENST00000467211.1
RP4-583P15.14
chr15_+_75494214 0.57 ENST00000394987.4
chromosome 15 open reading frame 39
chr20_+_44509857 0.57 ENST00000372523.1
ENST00000372520.1
zinc finger, SWIM-type containing 1
chr3_-_125655882 0.57 ENST00000340333.3
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase-like
chr1_+_27561104 0.56 ENST00000361771.3
WD and tetratricopeptide repeats 1
chr6_-_33282163 0.56 ENST00000434618.2
ENST00000456592.2
TAP binding protein (tapasin)
chr22_-_51066521 0.55 ENST00000395621.3
ENST00000395619.3
ENST00000356098.5
ENST00000216124.5
ENST00000453344.2
ENST00000547307.1
ENST00000547805.1
arylsulfatase A
chr11_-_57177586 0.54 ENST00000529411.1
Uncharacterized protein
chr6_+_43737939 0.54 ENST00000372067.3
vascular endothelial growth factor A
chr17_-_8198636 0.54 ENST00000577745.1
ENST00000579192.1
ENST00000396278.1
solute carrier family 25, member 35
chr17_+_39261584 0.54 ENST00000391415.1
keratin associated protein 4-9
chr9_+_35673853 0.53 ENST00000378357.4
carbonic anhydrase IX
chr13_+_73302047 0.53 ENST00000377814.2
ENST00000377815.3
ENST00000390667.5
bora, aurora kinase A activator
chr12_-_95467267 0.53 ENST00000330677.7
nuclear receptor subfamily 2, group C, member 1
chr21_+_45432174 0.53 ENST00000380221.3
ENST00000291574.4
trafficking protein particle complex 10
chr6_+_106546808 0.53 ENST00000369089.3
PR domain containing 1, with ZNF domain
chr1_+_180123969 0.52 ENST00000367602.3
ENST00000367600.5
quiescin Q6 sulfhydryl oxidase 1
chr19_-_10687907 0.51 ENST00000589348.1
adaptor-related protein complex 1, mu 2 subunit
chr17_-_39254391 0.51 ENST00000333822.4
keratin associated protein 4-8
chr5_-_176981417 0.51 ENST00000514747.1
ENST00000443375.2
ENST00000329540.5
family with sequence similarity 193, member B
chr8_-_145331153 0.49 ENST00000377412.4
KM-PA-2 protein; Uncharacterized protein
chr2_-_27603582 0.49 ENST00000323703.6
ENST00000436006.1
zinc finger protein 513
chr12_-_117318788 0.49 ENST00000550505.1
harakiri, BCL2 interacting protein (contains only BH3 domain)

Network of associatons between targets according to the STRING database.

First level regulatory network of RXRA_NR2F6_NR2C2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 10.8 GO:0070902 mitochondrial tRNA pseudouridine synthesis(GO:0070902)
1.7 8.4 GO:0003069 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
1.6 16.2 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.7 8.2 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.7 2.1 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.6 2.6 GO:0006238 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.6 1.8 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450) response to biotin(GO:0070781)
0.6 1.7 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.5 3.1 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.5 4.4 GO:0001554 luteolysis(GO:0001554)
0.5 2.8 GO:0010732 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.4 2.1 GO:0015692 lead ion transport(GO:0015692)
0.4 1.7 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.4 1.7 GO:0014040 positive regulation of Schwann cell differentiation(GO:0014040)
0.4 1.5 GO:0002215 defense response to nematode(GO:0002215)
0.3 1.7 GO:0032218 riboflavin transport(GO:0032218)
0.3 1.6 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.3 6.6 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.3 1.5 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.3 1.4 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.3 2.0 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.3 1.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.3 0.8 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.3 1.3 GO:1902164 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.3 2.1 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.2 1.0 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 1.0 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.2 0.7 GO:1904106 protein localization to microvillus(GO:1904106)
0.2 1.7 GO:0080009 mRNA methylation(GO:0080009)
0.2 1.8 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.2 2.3 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.2 1.7 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.2 1.0 GO:1902896 terminal web assembly(GO:1902896)
0.2 1.6 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.2 0.5 GO:0071301 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.2 0.5 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.2 0.5 GO:0050823 peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823)
0.2 2.5 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.2 0.6 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.2 1.6 GO:1903874 ferrous iron transport(GO:0015684) ferrous iron transmembrane transport(GO:1903874)
0.1 1.5 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.1 0.9 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 1.5 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 1.0 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1 0.7 GO:0019303 D-ribose catabolic process(GO:0019303)
0.1 0.7 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.1 0.4 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.1 4.0 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.1 2.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.5 GO:0000103 sulfate assimilation(GO:0000103)
0.1 0.7 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 1.3 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.1 1.7 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.1 0.5 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.1 0.5 GO:1990928 response to amino acid starvation(GO:1990928)
0.1 0.3 GO:1990927 calcium ion regulated lysosome exocytosis(GO:1990927)
0.1 0.7 GO:0070475 rRNA base methylation(GO:0070475)
0.1 0.3 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.1 0.7 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.1 1.0 GO:0006600 creatine metabolic process(GO:0006600)
0.1 1.7 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.3 GO:0002894 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.1 0.8 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.5 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.1 0.1 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.1 0.4 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 0.7 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 0.3 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.1 0.2 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.1 0.5 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.2 GO:0052031 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
0.1 0.9 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.1 0.3 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.1 0.4 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.1 0.7 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 1.7 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.4 GO:0021633 optic nerve structural organization(GO:0021633)
0.1 0.5 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 0.4 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1 0.7 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.1 0.7 GO:0014870 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.8 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.1 1.1 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.1 0.1 GO:2000395 regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.1 2.0 GO:0000042 protein targeting to Golgi(GO:0000042)
0.1 0.2 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.1 0.3 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.1 0.2 GO:2000532 renal albumin absorption(GO:0097018) regulation of renal albumin absorption(GO:2000532) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.1 0.1 GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903)
0.1 0.1 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.1 0.4 GO:0006477 protein sulfation(GO:0006477)
0.1 0.2 GO:0045578 negative regulation of B cell differentiation(GO:0045578) negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.1 0.9 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 0.3 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.1 0.6 GO:0090261 negative regulation of cAMP-mediated signaling(GO:0043951) positive regulation of inclusion body assembly(GO:0090261)
0.1 0.2 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.1 0.2 GO:0002525 acute inflammatory response to non-antigenic stimulus(GO:0002525) regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877) positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.1 0.7 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.2 GO:0043606 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.2 GO:2001178 mediator complex assembly(GO:0036034) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178)
0.0 0.8 GO:1903543 positive regulation of exosomal secretion(GO:1903543)
0.0 1.5 GO:0006735 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 1.7 GO:0038202 TORC1 signaling(GO:0038202)
0.0 0.1 GO:1904808 regulation of protein oxidation(GO:1904806) positive regulation of protein oxidation(GO:1904808)
0.0 0.1 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.0 0.4 GO:0016191 synaptic vesicle uncoating(GO:0016191) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.4 GO:0042262 DNA protection(GO:0042262)
0.0 0.2 GO:0033131 regulation of glucokinase activity(GO:0033131) regulation of hexokinase activity(GO:1903299)
0.0 0.2 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 1.0 GO:0006825 copper ion transport(GO:0006825)
0.0 0.5 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.0 0.2 GO:0009644 response to high light intensity(GO:0009644)
0.0 0.2 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.2 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.2 GO:0002351 serotonin production involved in inflammatory response(GO:0002351) serotonin secretion involved in inflammatory response(GO:0002442) serotonin secretion by platelet(GO:0002554)
0.0 0.1 GO:0061055 myotome development(GO:0061055)
0.0 0.7 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.8 GO:0060134 prepulse inhibition(GO:0060134)
0.0 1.1 GO:0043586 tongue development(GO:0043586)
0.0 0.5 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.1 GO:0036116 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.0 0.5 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.2 GO:0071105 response to interleukin-11(GO:0071105)
0.0 0.9 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.3 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 3.1 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.2 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.0 1.0 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 0.1 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.0 4.1 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0 0.5 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.3 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.1 GO:1905068 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 1.1 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.4 GO:0006924 activation-induced cell death of T cells(GO:0006924)
0.0 0.3 GO:0032264 IMP salvage(GO:0032264)
0.0 2.3 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)
0.0 0.2 GO:0034651 cortisol metabolic process(GO:0034650) cortisol biosynthetic process(GO:0034651) cellular response to potassium ion(GO:0035865)
0.0 0.3 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.7 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.5 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.5 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.0 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.2 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.0 0.1 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.0 0.2 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.3 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
0.0 0.3 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.0 0.3 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.8 GO:0046688 response to copper ion(GO:0046688)
0.0 0.8 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.1 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.5 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 1.5 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.4 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 2.2 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:0051941 regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.0 0.2 GO:0051660 cortical microtubule organization(GO:0043622) establishment of centrosome localization(GO:0051660) regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.3 GO:0021978 telencephalon regionalization(GO:0021978)
0.0 0.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.4 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.0 3.2 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.3 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.4 GO:0051601 exocyst localization(GO:0051601)
0.0 0.7 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.8 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.2 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.1 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.0 0.1 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.0 0.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.3 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.1 GO:1900825 regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
0.0 0.1 GO:0051106 positive regulation of DNA ligation(GO:0051106)
0.0 0.6 GO:0097502 mannosylation(GO:0097502)
0.0 0.2 GO:0072015 glomerular visceral epithelial cell development(GO:0072015)
0.0 1.2 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 1.2 GO:0006400 tRNA modification(GO:0006400)
0.0 1.7 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.3 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
0.0 0.1 GO:0002005 angiotensin catabolic process in blood(GO:0002005)
0.0 0.4 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 0.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.6 GO:0008334 histone mRNA metabolic process(GO:0008334)
0.0 0.5 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.1 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.0 GO:0048880 sensory system development(GO:0048880)
0.0 0.5 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 0.2 GO:0043383 negative T cell selection(GO:0043383)
0.0 0.5 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.0 0.2 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 1.6 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.0 1.2 GO:0042058 regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
0.0 0.5 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.3 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.1 GO:0060290 transdifferentiation(GO:0060290)
0.0 0.2 GO:0046519 sphingoid metabolic process(GO:0046519)
0.0 0.6 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.1 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.2 GO:0060285 cilium-dependent cell motility(GO:0060285)
0.0 0.2 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.2 GO:0001510 RNA methylation(GO:0001510)
0.0 0.0 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.7 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.5 1.5 GO:0071159 NF-kappaB complex(GO:0071159)
0.4 1.7 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.4 2.1 GO:0070826 paraferritin complex(GO:0070826)
0.3 1.7 GO:0032021 NELF complex(GO:0032021)
0.3 2.9 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.3 2.0 GO:1990130 Iml1 complex(GO:1990130)
0.3 1.4 GO:0036398 TCR signalosome(GO:0036398)
0.3 0.8 GO:0033565 ESCRT-0 complex(GO:0033565)
0.2 1.5 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.2 0.7 GO:0045160 myosin I complex(GO:0045160)
0.2 1.3 GO:0031415 NatA complex(GO:0031415)
0.1 2.9 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 1.7 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 1.0 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 1.5 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 0.5 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 0.5 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.1 1.6 GO:0000815 ESCRT III complex(GO:0000815)
0.1 0.3 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.1 0.7 GO:0014802 terminal cisterna(GO:0014802)
0.1 0.3 GO:0044393 microspike(GO:0044393)
0.1 2.7 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.1 2.0 GO:0043194 axon initial segment(GO:0043194)
0.1 2.7 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 0.7 GO:0000125 PCAF complex(GO:0000125) pre-snoRNP complex(GO:0070761)
0.1 0.2 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 0.7 GO:0005638 lamin filament(GO:0005638)
0.1 0.6 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.1 0.5 GO:0042825 TAP complex(GO:0042825)
0.1 0.7 GO:0031931 TORC1 complex(GO:0031931)
0.1 2.0 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 0.2 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.1 0.8 GO:0060091 kinocilium(GO:0060091)
0.1 0.2 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 2.6 GO:0016592 mediator complex(GO:0016592)
0.1 0.3 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.1 35.1 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.4 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.7 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.6 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.3 GO:0043196 varicosity(GO:0043196)
0.0 0.4 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.0 0.4 GO:0043203 axon hillock(GO:0043203)
0.0 3.4 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.7 GO:0032433 filopodium tip(GO:0032433)
0.0 0.7 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.3 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.9 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 1.4 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.5 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.4 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 0.3 GO:0032009 early phagosome(GO:0032009)
0.0 0.1 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.3 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.2 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.5 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 3.9 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 1.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.2 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 2.6 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.5 GO:0031528 microvillus membrane(GO:0031528)
0.0 2.4 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.7 GO:0032040 small-subunit processome(GO:0032040)
0.0 2.3 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.7 GO:0032420 stereocilium(GO:0032420)
0.0 0.2 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.9 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.9 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.3 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 4.6 GO:0031965 nuclear membrane(GO:0031965)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 10.8 GO:0004730 pseudouridylate synthase activity(GO:0004730)
3.2 16.2 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
1.0 9.2 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.5 3.1 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.5 2.5 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.5 3.4 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.4 2.1 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.4 1.6 GO:0004743 pyruvate kinase activity(GO:0004743)
0.4 1.6 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.4 1.9 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.4 1.1 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.3 1.7 GO:0032217 riboflavin transporter activity(GO:0032217)
0.3 1.0 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.3 0.9 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.3 2.9 GO:0015288 porin activity(GO:0015288)
0.3 0.8 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.3 3.6 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.2 2.6 GO:0004849 uridine kinase activity(GO:0004849)
0.2 1.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.2 1.5 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 2.6 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.2 2.8 GO:0042301 phosphate ion binding(GO:0042301)
0.2 0.5 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.2 2.0 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.2 0.9 GO:0016531 copper chaperone activity(GO:0016531)
0.2 0.7 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.2 1.5 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.2 0.6 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 0.6 GO:0001855 complement component C4b binding(GO:0001855)
0.1 0.8 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.1 1.0 GO:0004111 creatine kinase activity(GO:0004111)
0.1 2.3 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 1.2 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.1 0.3 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1 0.7 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 0.8 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 0.5 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.1 1.0 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.1 0.3 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.1 0.4 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.1 0.5 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.1 1.0 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 2.3 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 0.5 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 1.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 1.8 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.3 GO:0015234 thiamine transmembrane transporter activity(GO:0015234)
0.1 0.2 GO:0004507 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.1 1.4 GO:0070513 death domain binding(GO:0070513)
0.1 2.1 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 4.4 GO:0070888 E-box binding(GO:0070888)
0.1 0.5 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.1 0.5 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 0.2 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.1 0.4 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.1 0.2 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 0.4 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.2 GO:0004967 glucagon receptor activity(GO:0004967)
0.1 0.2 GO:0005471 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.1 0.3 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.1 0.4 GO:0030613 oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
0.1 0.2 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.1 0.2 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 0.2 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.1 1.4 GO:0030275 LRR domain binding(GO:0030275)
0.1 1.8 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 3.0 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.3 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 1.7 GO:0001848 complement binding(GO:0001848)
0.0 2.5 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 1.3 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.9 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.1 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.7 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.2 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 1.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.7 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 2.2 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.2 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.5 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.3 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 4.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.3 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 5.2 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.7 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 2.6 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.2 GO:0019239 deaminase activity(GO:0019239)
0.0 0.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.3 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.2 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.2 GO:0034711 inhibin binding(GO:0034711)
0.0 0.2 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 5.9 GO:0004386 helicase activity(GO:0004386)
0.0 1.9 GO:0000049 tRNA binding(GO:0000049)
0.0 0.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.7 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.3 GO:0000182 rDNA binding(GO:0000182)
0.0 0.3 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.7 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.7 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.1 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 2.3 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.4 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.5 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.5 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.1 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.1 GO:0034191 apolipoprotein A-I receptor binding(GO:0034191)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.7 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 1.1 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.7 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.3 GO:0033691 sialic acid binding(GO:0033691)
0.0 1.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.3 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.3 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.2 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.7 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.2 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.3 GO:0019841 retinol binding(GO:0019841)
0.0 0.7 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.8 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.1 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.1 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups(GO:0016725) molybdopterin cofactor binding(GO:0043546)
0.0 0.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.4 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 1.6 GO:0020037 heme binding(GO:0020037)
0.0 0.6 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.2 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.1 8.0 PID FOXO PATHWAY FoxO family signaling
0.1 6.5 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.1 2.2 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.1 1.7 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 2.4 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.1 1.6 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.5 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.5 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.3 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 1.8 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.0 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.4 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 3.0 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 2.5 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.8 PID BMP PATHWAY BMP receptor signaling
0.0 0.3 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 1.4 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.6 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.2 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.6 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.5 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 1.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 3.2 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.2 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.7 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.6 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.6 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.6 PID PLK1 PATHWAY PLK1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 9.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.2 6.7 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.2 1.8 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 0.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 3.4 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 8.9 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 2.5