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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for SCRT1_SCRT2

Z-value: 0.57

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Transcription factors associated with SCRT1_SCRT2

Gene Symbol Gene ID Gene Info
SCRT1
ENSG00000170616.9 scratch family transcriptional repressor 1
SCRT2
ENSG00000215397.3 scratch family transcriptional repressor 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SCRT1hg19_v2_chr8_-_145559943_145559943-0.386.3e-02Click!

Activity profile of SCRT1_SCRT2 motif

Sorted Z-values of SCRT1_SCRT2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_41540160 2.17 ENST00000503057.1
ENST00000511496.1
LIMCH1
LIM and calponin homology domains 1
chr21_-_35987438 1.29 ENST00000313806.4
RCAN1
regulator of calcineurin 1
chr10_+_35484793 1.05 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
CREM
cAMP responsive element modulator
chr4_-_90757364 1.00 ENST00000508895.1
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr7_+_114562172 0.93 ENST00000393486.1
ENST00000257724.3
MDFIC
MyoD family inhibitor domain containing
chr2_+_173600671 0.88 ENST00000409036.1
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr8_+_98881268 0.81 ENST00000254898.5
ENST00000524308.1
ENST00000522025.2
MATN2
matrilin 2
chr6_-_10419871 0.77 ENST00000319516.4
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr16_+_67063262 0.75 ENST00000565389.1
CBFB
core-binding factor, beta subunit
chr4_-_10117949 0.72 ENST00000508079.1
WDR1
WD repeat domain 1
chr10_+_35484053 0.71 ENST00000487763.1
ENST00000473940.1
ENST00000488328.1
ENST00000356917.5
CREM
cAMP responsive element modulator
chr17_+_78194205 0.70 ENST00000573809.1
ENST00000361193.3
ENST00000574967.1
ENST00000576126.1
ENST00000411502.3
ENST00000546047.2
SLC26A11
solute carrier family 26 (anion exchanger), member 11
chr20_-_50159198 0.64 ENST00000371564.3
ENST00000396009.3
ENST00000610033.1
NFATC2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr2_+_173600514 0.61 ENST00000264111.6
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr12_-_117318788 0.60 ENST00000550505.1
HRK
harakiri, BCL2 interacting protein (contains only BH3 domain)
chr2_+_173600565 0.58 ENST00000397081.3
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr7_-_122526499 0.58 ENST00000412584.2
CADPS2
Ca++-dependent secretion activator 2
chr11_+_61583721 0.50 ENST00000257261.6
FADS2
fatty acid desaturase 2
chr2_+_101437487 0.50 ENST00000427413.1
ENST00000542504.1
NPAS2
neuronal PAS domain protein 2
chr6_-_31697563 0.49 ENST00000375789.2
ENST00000416410.1
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr10_+_97515409 0.49 ENST00000371207.3
ENST00000543964.1
ENTPD1
ectonucleoside triphosphate diphosphohydrolase 1
chr6_-_31697255 0.47 ENST00000436437.1
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr7_+_20370746 0.42 ENST00000222573.4
ITGB8
integrin, beta 8
chr11_-_71159380 0.41 ENST00000525346.1
ENST00000531364.1
ENST00000529990.1
ENST00000527316.1
ENST00000407721.2
DHCR7
7-dehydrocholesterol reductase
chr8_+_120220561 0.41 ENST00000276681.6
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr10_+_6779326 0.39 ENST00000417112.1
RP11-554I8.2
RP11-554I8.2
chr14_+_23776024 0.39 ENST00000553781.1
ENST00000556100.1
ENST00000557236.1
ENST00000557579.1
BCL2L2-PABPN1
BCL2L2
BCL2L2-PABPN1 readthrough
BCL2-like 2
chr1_+_55271736 0.38 ENST00000358193.3
ENST00000371273.3
C1orf177
chromosome 1 open reading frame 177
chr6_+_90272027 0.38 ENST00000522441.1
ANKRD6
ankyrin repeat domain 6
chr14_+_23776167 0.38 ENST00000554635.1
ENST00000557008.1
BCL2L2
BCL2L2-PABPN1
BCL2-like 2
BCL2L2-PABPN1 readthrough
chr10_-_101945771 0.38 ENST00000370408.2
ENST00000407654.3
ERLIN1
ER lipid raft associated 1
chr3_+_141144963 0.37 ENST00000510726.1
ZBTB38
zinc finger and BTB domain containing 38
chrX_+_55744228 0.36 ENST00000262850.7
RRAGB
Ras-related GTP binding B
chr2_-_24583583 0.35 ENST00000355123.4
ITSN2
intersectin 2
chr16_+_67063855 0.35 ENST00000563939.2
CBFB
core-binding factor, beta subunit
chr8_-_133772794 0.35 ENST00000519187.1
ENST00000523829.1
ENST00000356838.3
ENST00000377901.4
ENST00000519304.1
TMEM71
transmembrane protein 71
chr10_-_60027642 0.34 ENST00000373935.3
IPMK
inositol polyphosphate multikinase
chr13_+_32313658 0.34 ENST00000380314.1
ENST00000298386.2
RXFP2
relaxin/insulin-like family peptide receptor 2
chr5_-_177423243 0.34 ENST00000308304.2
PROP1
PROP paired-like homeobox 1
chr15_-_34628951 0.32 ENST00000397707.2
ENST00000560611.1
SLC12A6
solute carrier family 12 (potassium/chloride transporter), member 6
chr4_+_120133791 0.31 ENST00000274030.6
USP53
ubiquitin specific peptidase 53
chr12_-_31478428 0.31 ENST00000543615.1
FAM60A
family with sequence similarity 60, member A
chr20_-_43977055 0.30 ENST00000372733.3
ENST00000537976.1
SDC4
syndecan 4
chr19_-_18391708 0.30 ENST00000600972.1
JUND
jun D proto-oncogene
chr2_-_24583168 0.29 ENST00000361999.3
ITSN2
intersectin 2
chr1_-_204135450 0.27 ENST00000272190.8
ENST00000367195.2
REN
renin
chr12_-_71003568 0.27 ENST00000547715.1
ENST00000451516.2
ENST00000538708.1
ENST00000550857.1
ENST00000261266.5
PTPRB
protein tyrosine phosphatase, receptor type, B
chr3_+_49044798 0.26 ENST00000438660.1
ENST00000608424.1
ENST00000415265.2
WDR6
WD repeat domain 6
chr5_+_125758813 0.25 ENST00000285689.3
ENST00000515200.1
GRAMD3
GRAM domain containing 3
chr11_+_64002292 0.25 ENST00000426086.2
VEGFB
vascular endothelial growth factor B
chr1_-_111217603 0.24 ENST00000369769.2
KCNA3
potassium voltage-gated channel, shaker-related subfamily, member 3
chr11_+_44748361 0.24 ENST00000533202.1
ENST00000533080.1
ENST00000520358.2
ENST00000520999.2
TSPAN18
tetraspanin 18
chr5_+_125758865 0.24 ENST00000542322.1
ENST00000544396.1
GRAMD3
GRAM domain containing 3
chr12_+_103981044 0.24 ENST00000388887.2
STAB2
stabilin 2
chr20_-_45061695 0.24 ENST00000445496.2
ELMO2
engulfment and cell motility 2
chrX_+_51928002 0.24 ENST00000375626.3
MAGED4
melanoma antigen family D, 4
chrX_-_99986494 0.24 ENST00000372989.1
ENST00000455616.1
ENST00000454200.2
ENST00000276141.6
SYTL4
synaptotagmin-like 4
chrX_-_51812268 0.24 ENST00000486010.1
ENST00000497164.1
ENST00000360134.6
ENST00000485287.1
ENST00000335504.5
ENST00000431659.1
MAGED4B
melanoma antigen family D, 4B
chrX_+_15518923 0.24 ENST00000348343.6
BMX
BMX non-receptor tyrosine kinase
chrX_+_51927919 0.23 ENST00000416960.1
MAGED4
melanoma antigen family D, 4
chr2_+_62423242 0.23 ENST00000301998.4
B3GNT2
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
chr22_+_44576770 0.23 ENST00000444313.3
ENST00000416291.1
PARVG
parvin, gamma
chr5_-_111091948 0.22 ENST00000447165.2
NREP
neuronal regeneration related protein
chr19_-_7990991 0.22 ENST00000318978.4
CTXN1
cortexin 1
chrX_-_134232630 0.22 ENST00000535837.1
ENST00000433425.2
LINC00087
long intergenic non-protein coding RNA 87
chr22_-_22090043 0.21 ENST00000403503.1
YPEL1
yippee-like 1 (Drosophila)
chrX_-_55057403 0.21 ENST00000396198.3
ENST00000335854.4
ENST00000455688.1
ENST00000330807.5
ALAS2
aminolevulinate, delta-, synthase 2
chr1_+_222988406 0.20 ENST00000448808.1
ENST00000457636.1
ENST00000439440.1
RP11-452F19.3
RP11-452F19.3
chr1_+_179851176 0.20 ENST00000528443.2
TOR1AIP1
torsin A interacting protein 1
chr8_-_91657740 0.20 ENST00000422900.1
TMEM64
transmembrane protein 64
chr3_+_151986709 0.20 ENST00000495875.2
ENST00000493459.1
ENST00000324210.5
ENST00000459747.1
MBNL1
muscleblind-like splicing regulator 1
chr16_-_29757272 0.20 ENST00000329410.3
C16orf54
chromosome 16 open reading frame 54
chr1_-_9129895 0.20 ENST00000473209.1
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chrX_-_70150939 0.19 ENST00000374299.3
ENST00000298085.4
SLC7A3
solute carrier family 7 (cationic amino acid transporter, y+ system), member 3
chr11_+_842808 0.19 ENST00000397397.2
ENST00000397411.2
ENST00000397396.1
TSPAN4
tetraspanin 4
chr11_+_842928 0.19 ENST00000397408.1
TSPAN4
tetraspanin 4
chr6_+_108977520 0.19 ENST00000540898.1
FOXO3
forkhead box O3
chr18_+_52495426 0.18 ENST00000262094.5
RAB27B
RAB27B, member RAS oncogene family
chr3_-_179754556 0.17 ENST00000263962.8
PEX5L
peroxisomal biogenesis factor 5-like
chr3_-_72496035 0.17 ENST00000477973.2
RYBP
RING1 and YY1 binding protein
chrX_+_51636629 0.17 ENST00000375722.1
ENST00000326587.7
ENST00000375695.2
MAGED1
melanoma antigen family D, 1
chr19_-_11373128 0.17 ENST00000294618.7
DOCK6
dedicator of cytokinesis 6
chrX_+_118370211 0.17 ENST00000217971.7
PGRMC1
progesterone receptor membrane component 1
chr8_+_82644669 0.16 ENST00000297265.4
CHMP4C
charged multivesicular body protein 4C
chr4_+_980785 0.16 ENST00000247933.4
ENST00000453894.1
IDUA
iduronidase, alpha-L-
chr1_+_16083154 0.16 ENST00000375771.1
FBLIM1
filamin binding LIM protein 1
chr6_-_27440460 0.16 ENST00000377419.1
ZNF184
zinc finger protein 184
chr16_-_50402690 0.16 ENST00000394689.2
BRD7
bromodomain containing 7
chr20_-_23402028 0.16 ENST00000398425.3
ENST00000432543.2
ENST00000377026.4
NAPB
N-ethylmaleimide-sensitive factor attachment protein, beta
chr22_+_44577237 0.16 ENST00000415224.1
ENST00000417767.1
PARVG
parvin, gamma
chr3_+_141144954 0.16 ENST00000441582.2
ENST00000321464.5
ZBTB38
zinc finger and BTB domain containing 38
chr7_+_130126165 0.16 ENST00000427521.1
ENST00000416162.2
ENST00000378576.4
MEST
mesoderm specific transcript
chr1_+_222988464 0.16 ENST00000420335.1
RP11-452F19.3
RP11-452F19.3
chr6_-_27440837 0.16 ENST00000211936.6
ZNF184
zinc finger protein 184
chr17_+_53343577 0.15 ENST00000573945.1
HLF
hepatic leukemia factor
chr12_+_50794730 0.15 ENST00000523389.1
ENST00000518561.1
ENST00000347328.5
ENST00000550260.1
LARP4
La ribonucleoprotein domain family, member 4
chr7_+_130126012 0.15 ENST00000341441.5
MEST
mesoderm specific transcript
chr19_+_35739782 0.15 ENST00000347609.4
LSR
lipolysis stimulated lipoprotein receptor
chr19_+_35739897 0.15 ENST00000605618.1
ENST00000427250.1
ENST00000601623.1
LSR
lipolysis stimulated lipoprotein receptor
chr9_-_126692386 0.15 ENST00000373624.2
ENST00000394219.3
ENST00000373620.3
ENST00000394215.2
ENST00000373618.1
DENND1A
DENN/MADD domain containing 1A
chr5_-_147211190 0.15 ENST00000510027.2
SPINK1
serine peptidase inhibitor, Kazal type 1
chr5_-_147211226 0.14 ENST00000296695.5
SPINK1
serine peptidase inhibitor, Kazal type 1
chr11_+_65779283 0.14 ENST00000312134.2
CST6
cystatin E/M
chr5_+_74011328 0.14 ENST00000513336.1
HEXB
hexosaminidase B (beta polypeptide)
chr19_+_35739597 0.13 ENST00000361790.3
LSR
lipolysis stimulated lipoprotein receptor
chr19_+_12862604 0.13 ENST00000553030.1
BEST2
bestrophin 2
chr20_+_30028322 0.13 ENST00000376309.3
DEFB123
defensin, beta 123
chr17_-_40288449 0.13 ENST00000552162.1
ENST00000550504.1
RAB5C
RAB5C, member RAS oncogene family
chr19_+_35739631 0.13 ENST00000602003.1
ENST00000360798.3
ENST00000354900.3
LSR
lipolysis stimulated lipoprotein receptor
chr19_+_35739280 0.13 ENST00000602122.1
LSR
lipolysis stimulated lipoprotein receptor
chr12_+_16500037 0.13 ENST00000536371.1
ENST00000010404.2
MGST1
microsomal glutathione S-transferase 1
chr16_+_103816 0.13 ENST00000383018.3
ENST00000417493.1
SNRNP25
small nuclear ribonucleoprotein 25kDa (U11/U12)
chr13_+_49551020 0.13 ENST00000541916.1
FNDC3A
fibronectin type III domain containing 3A
chr1_-_154928562 0.13 ENST00000368463.3
ENST00000539880.1
ENST00000542459.1
ENST00000368460.3
ENST00000368465.1
PBXIP1
pre-B-cell leukemia homeobox interacting protein 1
chr1_-_94312706 0.13 ENST00000370244.1
BCAR3
breast cancer anti-estrogen resistance 3
chr15_-_30113676 0.13 ENST00000400011.2
TJP1
tight junction protein 1
chr7_-_122526799 0.13 ENST00000334010.7
ENST00000313070.7
CADPS2
Ca++-dependent secretion activator 2
chr17_-_2966901 0.12 ENST00000575751.1
OR1D5
olfactory receptor, family 1, subfamily D, member 5
chr15_-_30114231 0.12 ENST00000356107.6
ENST00000545208.2
TJP1
tight junction protein 1
chr14_+_23775971 0.12 ENST00000250405.5
BCL2L2
BCL2-like 2
chr4_+_87856129 0.12 ENST00000395146.4
ENST00000507468.1
AFF1
AF4/FMR2 family, member 1
chr16_+_2286726 0.11 ENST00000382437.4
ENST00000569184.1
DNASE1L2
deoxyribonuclease I-like 2
chr4_-_140223670 0.11 ENST00000394228.1
ENST00000539387.1
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr12_-_67197760 0.11 ENST00000539540.1
ENST00000540433.1
ENST00000541947.1
ENST00000538373.1
GRIP1
glutamate receptor interacting protein 1
chr10_-_47222824 0.11 ENST00000355232.3
AGAP10
ArfGAP with GTPase domain, ankyrin repeat and PH domain 10
chr1_+_150245099 0.11 ENST00000369099.3
C1orf54
chromosome 1 open reading frame 54
chr19_-_51220176 0.11 ENST00000359082.3
ENST00000293441.1
SHANK1
SH3 and multiple ankyrin repeat domains 1
chr2_-_61244308 0.11 ENST00000407787.1
ENST00000398658.2
PUS10
pseudouridylate synthase 10
chr17_+_39261584 0.10 ENST00000391415.1
KRTAP4-9
keratin associated protein 4-9
chrX_-_99987088 0.10 ENST00000372981.1
ENST00000263033.5
SYTL4
synaptotagmin-like 4
chr5_+_72921983 0.10 ENST00000296794.6
ENST00000545377.1
ENST00000513042.2
ENST00000287898.5
ENST00000509848.1
ARHGEF28
Rho guanine nucleotide exchange factor (GEF) 28
chr5_+_148651409 0.10 ENST00000296721.4
AFAP1L1
actin filament associated protein 1-like 1
chrX_-_151143140 0.10 ENST00000393914.3
ENST00000370328.3
ENST00000370325.1
GABRE
gamma-aminobutyric acid (GABA) A receptor, epsilon
chr13_-_25746416 0.10 ENST00000515384.1
ENST00000357816.2
AMER2
APC membrane recruitment protein 2
chr4_-_83483395 0.10 ENST00000515780.2
TMEM150C
transmembrane protein 150C
chr4_-_110223523 0.09 ENST00000399127.1
COL25A1
collagen, type XXV, alpha 1
chr8_-_91657909 0.09 ENST00000418210.2
TMEM64
transmembrane protein 64
chr1_-_224033596 0.09 ENST00000391878.2
ENST00000343537.7
TP53BP2
tumor protein p53 binding protein, 2
chr1_+_20617362 0.09 ENST00000375079.2
ENST00000289815.8
ENST00000375083.4
ENST00000289825.4
VWA5B1
von Willebrand factor A domain containing 5B1
chrX_+_13707235 0.09 ENST00000464506.1
RAB9A
RAB9A, member RAS oncogene family
chr16_-_1031259 0.09 ENST00000563837.1
ENST00000563863.1
ENST00000565069.1
ENST00000570014.1
RP11-161M6.2
LMF1
RP11-161M6.2
lipase maturation factor 1
chr4_+_87856191 0.08 ENST00000503477.1
AFF1
AF4/FMR2 family, member 1
chr3_-_49851313 0.08 ENST00000333486.3
UBA7
ubiquitin-like modifier activating enzyme 7
chr20_+_57427765 0.08 ENST00000371100.4
GNAS
GNAS complex locus
chr14_-_71107921 0.08 ENST00000553982.1
ENST00000500016.1
CTD-2540L5.5
CTD-2540L5.6
CTD-2540L5.5
CTD-2540L5.6
chr17_-_34257731 0.08 ENST00000431884.2
ENST00000425909.3
ENST00000394528.3
ENST00000430160.2
RDM1
RAD52 motif 1
chr22_-_22090064 0.08 ENST00000339468.3
YPEL1
yippee-like 1 (Drosophila)
chr17_-_79805146 0.07 ENST00000415593.1
P4HB
prolyl 4-hydroxylase, beta polypeptide
chr22_-_30662828 0.07 ENST00000403463.1
ENST00000215781.2
OSM
oncostatin M
chr19_-_3062881 0.07 ENST00000586742.1
AES
amino-terminal enhancer of split
chr19_-_3063099 0.07 ENST00000221561.8
AES
amino-terminal enhancer of split
chr12_-_54071181 0.07 ENST00000338662.5
ATP5G2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr3_+_145782358 0.07 ENST00000422482.1
AC107021.1
HCG1786590; PRO2533; Uncharacterized protein
chrX_+_70503037 0.07 ENST00000535149.1
NONO
non-POU domain containing, octamer-binding
chr17_-_33760164 0.07 ENST00000445092.1
ENST00000394562.1
ENST00000447040.2
SLFN12
schlafen family member 12
chr15_+_84904525 0.07 ENST00000510439.2
GOLGA6L4
golgin A6 family-like 4
chr7_+_94536898 0.07 ENST00000433360.1
ENST00000340694.4
ENST00000424654.1
PPP1R9A
protein phosphatase 1, regulatory subunit 9A
chr17_-_34257771 0.07 ENST00000394529.3
ENST00000293273.6
RDM1
RAD52 motif 1
chr1_-_153940097 0.07 ENST00000413622.1
ENST00000310483.6
SLC39A1
solute carrier family 39 (zinc transporter), member 1
chr7_+_154795154 0.07 ENST00000608317.1
PAXIP1-AS1
PAXIP1 antisense RNA 1 (head to head)
chr2_+_10861775 0.07 ENST00000272238.4
ENST00000381661.3
ATP6V1C2
ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2
chr13_+_58206655 0.07 ENST00000377918.3
PCDH17
protocadherin 17
chr12_-_71148413 0.06 ENST00000440835.2
ENST00000549308.1
ENST00000550661.1
PTPRR
protein tyrosine phosphatase, receptor type, R
chr7_+_12727250 0.06 ENST00000404894.1
ARL4A
ADP-ribosylation factor-like 4A
chr19_-_42759300 0.06 ENST00000222329.4
ERF
Ets2 repressor factor
chr2_+_223289208 0.06 ENST00000321276.7
SGPP2
sphingosine-1-phosphate phosphatase 2
chr1_-_104239076 0.06 ENST00000370080.3
AMY1B
amylase, alpha 1B (salivary)
chr5_+_138089100 0.06 ENST00000520339.1
ENST00000355078.5
ENST00000302763.7
ENST00000518910.1
CTNNA1
catenin (cadherin-associated protein), alpha 1, 102kDa
chr5_+_140430979 0.06 ENST00000306549.3
PCDHB1
protocadherin beta 1
chr12_+_53342625 0.06 ENST00000388837.2
ENST00000550600.1
ENST00000388835.3
KRT18
keratin 18
chr10_+_26505662 0.06 ENST00000428517.2
GAD2
glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
chr2_+_24397930 0.06 ENST00000295150.3
FAM228A
family with sequence similarity 228, member A
chr17_-_2415169 0.06 ENST00000263092.6
ENST00000538844.1
ENST00000576976.1
METTL16
methyltransferase like 16
chr6_+_28092338 0.06 ENST00000340487.4
ZSCAN16
zinc finger and SCAN domain containing 16
chr1_-_95392635 0.06 ENST00000538964.1
ENST00000394202.4
ENST00000370206.4
CNN3
calponin 3, acidic
chr17_+_77704681 0.06 ENST00000328313.5
ENPP7
ectonucleotide pyrophosphatase/phosphodiesterase 7
chr12_-_71148357 0.06 ENST00000378778.1
PTPRR
protein tyrosine phosphatase, receptor type, R
chr16_+_1031762 0.06 ENST00000293894.3
SOX8
SRY (sex determining region Y)-box 8
chr17_-_33760269 0.05 ENST00000452764.3
SLFN12
schlafen family member 12
chr12_-_13153139 0.05 ENST00000536942.1
ENST00000014930.4
HEBP1
heme binding protein 1
chr1_+_150522222 0.05 ENST00000369039.5
ADAMTSL4
ADAMTS-like 4
chr17_-_27405875 0.05 ENST00000359450.6
TIAF1
TGFB1-induced anti-apoptotic factor 1
chr8_+_110374683 0.05 ENST00000378402.5
PKHD1L1
polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1
chr1_-_104238912 0.05 ENST00000330330.5
AMY1B
amylase, alpha 1B (salivary)
chr2_-_175870085 0.05 ENST00000409156.3
CHN1
chimerin 1
chr5_+_32710736 0.05 ENST00000415685.2
NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr1_-_225615599 0.05 ENST00000421383.1
ENST00000272163.4
LBR
lamin B receptor
chr3_-_143567262 0.05 ENST00000474151.1
ENST00000316549.6
SLC9A9
solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
chr5_-_114632307 0.05 ENST00000506442.1
ENST00000379611.5
CCDC112
coiled-coil domain containing 112
chr14_+_68086515 0.04 ENST00000261783.3
ARG2
arginase 2
chr5_-_127873496 0.04 ENST00000508989.1
FBN2
fibrillin 2
chr4_-_89619386 0.04 ENST00000323061.5
NAP1L5
nucleosome assembly protein 1-like 5
chr17_+_67410832 0.04 ENST00000590474.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr1_+_104198377 0.04 ENST00000370083.4
AMY1A
amylase, alpha 1A (salivary)
chr3_-_114343768 0.04 ENST00000393785.2
ZBTB20
zinc finger and BTB domain containing 20
chr1_-_247335269 0.04 ENST00000543802.2
ENST00000491356.1
ENST00000472531.1
ENST00000340684.6
ZNF124
zinc finger protein 124
chr1_-_201391149 0.04 ENST00000555948.1
ENST00000556362.1
TNNI1
troponin I type 1 (skeletal, slow)
chr2_-_24583314 0.04 ENST00000443927.1
ENST00000406921.3
ENST00000412011.1
ITSN2
intersectin 2
chr1_+_220701456 0.04 ENST00000366918.4
ENST00000402574.1
MARK1
MAP/microtubule affinity-regulating kinase 1
chr3_+_26664291 0.04 ENST00000396641.2
LRRC3B
leucine rich repeat containing 3B

Network of associatons between targets according to the STRING database.

First level regulatory network of SCRT1_SCRT2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:1903285 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.2 0.8 GO:0003409 optic cup structural organization(GO:0003409)
0.2 0.7 GO:0042247 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.1 0.7 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.1 0.9 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.1 0.3 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.1 0.4 GO:0033489 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.1 0.2 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.1 0.6 GO:1990504 dense core granule exocytosis(GO:1990504)
0.1 0.3 GO:0048850 hypophysis morphogenesis(GO:0048850)
0.1 0.3 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 0.2 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.1 0.3 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.1 0.2 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 0.4 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 0.2 GO:0035494 SNARE complex disassembly(GO:0035494)
0.1 1.0 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.7 GO:0019532 oxalate transport(GO:0019532)
0.0 0.3 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.3 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.0 0.1 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.0 0.2 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.0 0.4 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 1.6 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.0 0.1 GO:0050894 determination of affect(GO:0050894)
0.0 0.1 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.0 0.2 GO:1903401 lysine transport(GO:0015819) L-lysine transport(GO:1902022) L-lysine transmembrane transport(GO:1903401)
0.0 1.3 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.4 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.1 GO:0007619 courtship behavior(GO:0007619)
0.0 0.1 GO:0003335 corneocyte development(GO:0003335)
0.0 0.3 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.1 GO:0072034 renal vesicle induction(GO:0072034)
0.0 0.4 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 1.8 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.5 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.0 0.5 GO:0051775 response to redox state(GO:0051775)
0.0 0.2 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.5 GO:0036109 alpha-linolenic acid metabolic process(GO:0036109) linoleic acid metabolic process(GO:0043651)
0.0 0.1 GO:1904048 regulation of spontaneous neurotransmitter secretion(GO:1904048)
0.0 0.5 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.0 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.7 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.1 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.0 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.1 GO:0043000 Golgi to plasma membrane CFTR protein transport(GO:0043000)
0.0 1.7 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.4 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.9 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.2 GO:0032364 oxygen homeostasis(GO:0032364)
0.0 0.1 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.4 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.1 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405)
0.0 0.1 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.4 GO:0001556 oocyte maturation(GO:0001556)
0.0 0.8 GO:0008347 glial cell migration(GO:0008347)
0.0 0.2 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.1 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.1 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.2 GO:0005984 disaccharide metabolic process(GO:0005984)
0.0 0.2 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.1 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0042643 actomyosin, actin portion(GO:0042643)
0.1 0.4 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.1 0.7 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.9 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.4 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 1.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.3 GO:0035976 AP1 complex(GO:0035976)
0.0 0.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.2 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.4 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.1 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2 1.0 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 1.0 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 1.8 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.5 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1 0.3 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.1 0.4 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.2 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1 0.2 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 0.9 GO:0030957 Tat protein binding(GO:0030957)
0.1 0.7 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.2 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 0.2 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.3 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.9 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0031877 somatostatin receptor binding(GO:0031877)
0.0 0.3 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.3 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 1.5 GO:0030552 cAMP binding(GO:0030552)
0.0 0.2 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.5 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.1 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.3 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.0 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.0 0.3 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.4 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.2 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.4 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.0 GO:0016160 amylase activity(GO:0016160)
0.0 0.1 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.3 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.7 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.6 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.8 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.3 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.5 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.4 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.5 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.5 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.2 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 1.0 REACTOME AMYLOIDS Genes involved in Amyloids