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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for SHOX

Z-value: 0.73

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Transcription factors associated with SHOX

Gene Symbol Gene ID Gene Info
SHOX
ENSG00000185960.8 short stature homeobox
SHOX
ENSGR0000185960.8 short stature homeobox

Activity profile of SHOX motif

Sorted Z-values of SHOX motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_92777606 4.20 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L
sterile alpha motif domain containing 9-like
chr2_+_152214098 3.17 ENST00000243347.3
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr11_-_117747434 2.22 ENST00000529335.2
ENST00000530956.1
ENST00000260282.4
FXYD6
FXYD domain containing ion transport regulator 6
chr11_-_117748138 2.17 ENST00000527717.1
FXYD6
FXYD domain containing ion transport regulator 6
chr11_-_117747607 2.13 ENST00000540359.1
ENST00000539526.1
FXYD6
FXYD domain containing ion transport regulator 6
chr1_-_150738261 1.80 ENST00000448301.2
ENST00000368985.3
CTSS
cathepsin S
chr3_-_79816965 1.65 ENST00000464233.1
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr5_-_13944652 1.58 ENST00000265104.4
DNAH5
dynein, axonemal, heavy chain 5
chr7_-_22234381 1.55 ENST00000458533.1
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr5_-_24645078 1.50 ENST00000264463.4
CDH10
cadherin 10, type 2 (T2-cadherin)
chr2_+_103035102 1.48 ENST00000264260.2
IL18RAP
interleukin 18 receptor accessory protein
chr12_-_16761007 1.37 ENST00000354662.1
ENST00000441439.2
LMO3
LIM domain only 3 (rhombotin-like 2)
chr9_-_16728161 1.33 ENST00000603713.1
ENST00000603313.1
BNC2
basonuclin 2
chr6_-_87804815 1.25 ENST00000369582.2
CGA
glycoprotein hormones, alpha polypeptide
chr5_+_125758813 1.22 ENST00000285689.3
ENST00000515200.1
GRAMD3
GRAM domain containing 3
chr5_+_125758865 1.22 ENST00000542322.1
ENST00000544396.1
GRAMD3
GRAM domain containing 3
chr7_-_22233442 1.21 ENST00000401957.2
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr18_+_57567180 1.18 ENST00000316660.6
ENST00000269518.9
PMAIP1
phorbol-12-myristate-13-acetate-induced protein 1
chr17_-_77924627 1.17 ENST00000572862.1
ENST00000573782.1
ENST00000574427.1
ENST00000570373.1
ENST00000340848.7
ENST00000576768.1
TBC1D16
TBC1 domain family, member 16
chr11_+_75526212 1.10 ENST00000356136.3
UVRAG
UV radiation resistance associated
chr6_+_50061315 1.10 ENST00000415106.1
RP11-397G17.1
RP11-397G17.1
chr15_-_55562479 1.10 ENST00000564609.1
RAB27A
RAB27A, member RAS oncogene family
chr18_-_33709268 1.04 ENST00000269187.5
ENST00000590986.1
ENST00000440549.2
SLC39A6
solute carrier family 39 (zinc transporter), member 6
chr10_+_74451883 1.02 ENST00000373053.3
ENST00000357157.6
MCU
mitochondrial calcium uniporter
chr15_-_55562582 1.01 ENST00000396307.2
RAB27A
RAB27A, member RAS oncogene family
chr15_-_55563072 1.01 ENST00000567380.1
ENST00000565972.1
ENST00000569493.1
RAB27A
RAB27A, member RAS oncogene family
chr10_-_36812323 0.97 ENST00000543053.1
NAMPTL
nicotinamide phosphoribosyltransferase-like
chr5_-_150473127 0.97 ENST00000521001.1
TNIP1
TNFAIP3 interacting protein 1
chr15_+_75080883 0.91 ENST00000567571.1
CSK
c-src tyrosine kinase
chr6_+_26402465 0.89 ENST00000476549.2
ENST00000289361.6
ENST00000450085.2
ENST00000425234.2
ENST00000427334.1
ENST00000506698.1
BTN3A1
butyrophilin, subfamily 3, member A1
chr12_+_26348582 0.89 ENST00000535504.1
SSPN
sarcospan
chr2_-_145278475 0.88 ENST00000558170.2
ZEB2
zinc finger E-box binding homeobox 2
chr1_-_101360331 0.88 ENST00000416479.1
ENST00000370113.3
EXTL2
exostosin-like glycosyltransferase 2
chr11_+_33061543 0.87 ENST00000432887.1
ENST00000528898.1
ENST00000531632.2
TCP11L1
t-complex 11, testis-specific-like 1
chr6_+_26440700 0.86 ENST00000494393.1
ENST00000482451.1
ENST00000244519.2
ENST00000339789.4
ENST00000471353.1
ENST00000361232.3
ENST00000487627.1
ENST00000496719.1
ENST00000490254.1
ENST00000487272.1
BTN3A3
butyrophilin, subfamily 3, member A3
chr4_+_169418195 0.86 ENST00000261509.6
ENST00000335742.7
PALLD
palladin, cytoskeletal associated protein
chr12_-_51422017 0.85 ENST00000394904.3
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr16_+_57279004 0.84 ENST00000219204.3
ARL2BP
ADP-ribosylation factor-like 2 binding protein
chr2_-_136678123 0.83 ENST00000422708.1
DARS
aspartyl-tRNA synthetase
chr17_+_59489112 0.82 ENST00000335108.2
C17orf82
chromosome 17 open reading frame 82
chr3_-_157221380 0.81 ENST00000468233.1
VEPH1
ventricular zone expressed PH domain-containing 1
chr8_+_22424551 0.81 ENST00000523348.1
SORBS3
sorbin and SH3 domain containing 3
chr10_-_24770632 0.78 ENST00000596413.1
AL353583.1
AL353583.1
chr4_-_122085469 0.78 ENST00000057513.3
TNIP3
TNFAIP3 interacting protein 3
chr13_-_46716969 0.77 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr2_+_162272605 0.76 ENST00000389554.3
TBR1
T-box, brain, 1
chr4_-_116034979 0.76 ENST00000264363.2
NDST4
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
chr8_-_90996459 0.76 ENST00000517337.1
ENST00000409330.1
NBN
nibrin
chr5_+_66300446 0.75 ENST00000261569.7
MAST4
microtubule associated serine/threonine kinase family member 4
chr10_+_111765562 0.74 ENST00000360162.3
ADD3
adducin 3 (gamma)
chr17_+_39405939 0.74 ENST00000334109.2
KRTAP9-4
keratin associated protein 9-4
chr6_+_12007897 0.72 ENST00000437559.1
RP11-456H18.2
RP11-456H18.2
chr8_-_90996837 0.72 ENST00000519426.1
ENST00000265433.3
NBN
nibrin
chr3_+_130569429 0.71 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr6_+_135502501 0.70 ENST00000527615.1
ENST00000420123.2
ENST00000525369.1
ENST00000528774.1
ENST00000534121.1
ENST00000534044.1
ENST00000533624.1
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr10_+_24497704 0.68 ENST00000376456.4
ENST00000458595.1
KIAA1217
KIAA1217
chr6_-_9933500 0.67 ENST00000492169.1
OFCC1
orofacial cleft 1 candidate 1
chr18_+_59000815 0.67 ENST00000262717.4
CDH20
cadherin 20, type 2
chrX_-_21676442 0.66 ENST00000379499.2
KLHL34
kelch-like family member 34
chr8_+_50824233 0.66 ENST00000522124.1
SNTG1
syntrophin, gamma 1
chr6_+_26365443 0.66 ENST00000527422.1
ENST00000356386.2
ENST00000396934.3
ENST00000377708.2
ENST00000396948.1
ENST00000508906.2
BTN3A2
butyrophilin, subfamily 3, member A2
chr3_+_111717511 0.66 ENST00000478951.1
ENST00000393917.2
TAGLN3
transgelin 3
chr3_+_111717600 0.65 ENST00000273368.4
TAGLN3
transgelin 3
chr12_-_16759711 0.64 ENST00000447609.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr1_+_50569575 0.64 ENST00000371827.1
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chr13_-_84456527 0.62 ENST00000377084.2
SLITRK1
SLIT and NTRK-like family, member 1
chr2_-_145277569 0.62 ENST00000303660.4
ZEB2
zinc finger E-box binding homeobox 2
chr21_-_35899113 0.59 ENST00000492600.1
ENST00000481448.1
ENST00000381132.2
RCAN1
regulator of calcineurin 1
chr10_+_24755416 0.57 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
KIAA1217
chr3_+_129247479 0.57 ENST00000296271.3
RHO
rhodopsin
chr5_+_69321074 0.57 ENST00000380751.5
ENST00000380750.3
ENST00000503931.1
ENST00000506542.1
SERF1B
small EDRK-rich factor 1B (centromeric)
chr3_+_111718036 0.56 ENST00000455401.2
TAGLN3
transgelin 3
chr12_-_89746173 0.55 ENST00000308385.6
DUSP6
dual specificity phosphatase 6
chr3_-_167191814 0.55 ENST00000466903.1
ENST00000264677.4
SERPINI2
serpin peptidase inhibitor, clade I (pancpin), member 2
chr1_+_244515930 0.54 ENST00000366537.1
ENST00000308105.4
C1orf100
chromosome 1 open reading frame 100
chr7_-_14026063 0.53 ENST00000443608.1
ENST00000438956.1
ETV1
ets variant 1
chr12_+_26348246 0.53 ENST00000422622.2
SSPN
sarcospan
chr3_-_191000172 0.53 ENST00000427544.2
UTS2B
urotensin 2B
chr17_-_78450398 0.53 ENST00000306773.4
NPTX1
neuronal pentraxin I
chr1_-_152131703 0.52 ENST00000316073.3
RPTN
repetin
chr1_+_107683436 0.51 ENST00000370068.1
NTNG1
netrin G1
chr3_+_111393501 0.51 ENST00000393934.3
PLCXD2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr11_-_118023490 0.50 ENST00000324727.4
SCN4B
sodium channel, voltage-gated, type IV, beta subunit
chr3_-_157221357 0.49 ENST00000494677.1
VEPH1
ventricular zone expressed PH domain-containing 1
chr1_+_160160283 0.49 ENST00000368079.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr17_+_41363854 0.49 ENST00000588693.1
ENST00000588659.1
ENST00000541594.1
ENST00000536052.1
ENST00000331615.3
TMEM106A
transmembrane protein 106A
chr19_+_13135386 0.49 ENST00000360105.4
ENST00000588228.1
ENST00000591028.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr20_+_18488137 0.48 ENST00000450074.1
ENST00000262544.2
ENST00000336714.3
ENST00000377475.3
SEC23B
Sec23 homolog B (S. cerevisiae)
chr1_+_225600404 0.48 ENST00000366845.2
AC092811.1
AC092811.1
chr3_+_173116225 0.48 ENST00000457714.1
NLGN1
neuroligin 1
chr6_+_26402517 0.48 ENST00000414912.2
BTN3A1
butyrophilin, subfamily 3, member A1
chr2_-_208031943 0.48 ENST00000421199.1
ENST00000457962.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr3_+_121774202 0.48 ENST00000469710.1
ENST00000493101.1
ENST00000330540.2
ENST00000264468.5
CD86
CD86 molecule
chr13_+_77522632 0.47 ENST00000377462.1
IRG1
immunoresponsive 1 homolog (mouse)
chr6_-_36515177 0.47 ENST00000229812.7
STK38
serine/threonine kinase 38
chr19_+_48949030 0.47 ENST00000253237.5
GRWD1
glutamate-rich WD repeat containing 1
chr12_+_26348429 0.46 ENST00000242729.2
SSPN
sarcospan
chr6_-_49604545 0.46 ENST00000371175.4
ENST00000229810.7
RHAG
Rh-associated glycoprotein
chr4_+_71458012 0.45 ENST00000449493.2
AMBN
ameloblastin (enamel matrix protein)
chr12_+_18414446 0.45 ENST00000433979.1
PIK3C2G
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
chrX_+_153448107 0.45 ENST00000369935.5
OPN1MW
opsin 1 (cone pigments), medium-wave-sensitive
chr1_+_160160346 0.44 ENST00000368078.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr15_+_101420028 0.44 ENST00000557963.1
ENST00000346623.6
ALDH1A3
aldehyde dehydrogenase 1 family, member A3
chr12_-_88974236 0.44 ENST00000228280.5
ENST00000552044.1
ENST00000357116.4
KITLG
KIT ligand
chr14_-_51027838 0.43 ENST00000555216.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr8_-_57026541 0.43 ENST00000311923.1
MOS
v-mos Moloney murine sarcoma viral oncogene homolog
chr5_-_1882858 0.43 ENST00000511126.1
ENST00000231357.2
IRX4
iroquois homeobox 4
chr17_-_3030875 0.43 ENST00000328890.2
OR1G1
olfactory receptor, family 1, subfamily G, member 1
chrX_+_153409678 0.43 ENST00000369951.4
OPN1LW
opsin 1 (cone pigments), long-wave-sensitive
chr1_+_107682629 0.42 ENST00000370074.4
ENST00000370073.2
ENST00000370071.2
ENST00000542803.1
ENST00000370061.3
ENST00000370072.3
ENST00000370070.2
NTNG1
netrin G1
chr5_+_31193847 0.42 ENST00000514738.1
ENST00000265071.2
CDH6
cadherin 6, type 2, K-cadherin (fetal kidney)
chr11_-_124190184 0.42 ENST00000357438.2
OR8D2
olfactory receptor, family 8, subfamily D, member 2
chr17_+_39261584 0.42 ENST00000391415.1
KRTAP4-9
keratin associated protein 4-9
chr4_-_105416039 0.42 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr17_-_38911580 0.41 ENST00000312150.4
KRT25
keratin 25
chr3_+_149191723 0.41 ENST00000305354.4
TM4SF4
transmembrane 4 L six family member 4
chr19_-_3557570 0.40 ENST00000355415.2
MFSD12
major facilitator superfamily domain containing 12
chr14_+_22977587 0.40 ENST00000390504.1
TRAJ33
T cell receptor alpha joining 33
chr1_+_68150744 0.40 ENST00000370986.4
ENST00000370985.3
GADD45A
growth arrest and DNA-damage-inducible, alpha
chr2_+_223162866 0.39 ENST00000295226.1
CCDC140
coiled-coil domain containing 140
chr12_+_49621658 0.39 ENST00000541364.1
TUBA1C
tubulin, alpha 1c
chr11_+_24518723 0.39 ENST00000336930.6
ENST00000529015.1
ENST00000533227.1
LUZP2
leucine zipper protein 2
chr21_-_42219065 0.39 ENST00000400454.1
DSCAM
Down syndrome cell adhesion molecule
chr12_+_41831485 0.38 ENST00000539469.2
ENST00000298919.7
PDZRN4
PDZ domain containing ring finger 4
chrX_-_13835147 0.38 ENST00000493677.1
ENST00000355135.2
GPM6B
glycoprotein M6B
chr10_+_102222798 0.38 ENST00000343737.5
WNT8B
wingless-type MMTV integration site family, member 8B
chr10_-_14372870 0.38 ENST00000357447.2
FRMD4A
FERM domain containing 4A
chr1_+_183774240 0.38 ENST00000360851.3
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr19_-_56110859 0.38 ENST00000221665.3
ENST00000592585.1
FIZ1
FLT3-interacting zinc finger 1
chr1_+_101003687 0.37 ENST00000315033.4
GPR88
G protein-coupled receptor 88
chr6_+_12007963 0.37 ENST00000607445.1
RP11-456H18.2
RP11-456H18.2
chr3_+_182971018 0.37 ENST00000326505.3
B3GNT5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr17_-_39280419 0.37 ENST00000394014.1
KRTAP4-12
keratin associated protein 4-12
chr8_-_116504448 0.36 ENST00000518018.1
TRPS1
trichorhinophalangeal syndrome I
chr3_-_157824292 0.36 ENST00000483851.2
SHOX2
short stature homeobox 2
chr6_-_136788001 0.36 ENST00000544465.1
MAP7
microtubule-associated protein 7
chr5_-_59783882 0.36 ENST00000505507.2
ENST00000502484.2
PDE4D
phosphodiesterase 4D, cAMP-specific
chr4_-_39979576 0.36 ENST00000303538.8
ENST00000503396.1
PDS5A
PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr17_+_47448102 0.35 ENST00000576461.1
RP11-81K2.1
Uncharacterized protein
chr19_+_45458503 0.35 ENST00000337392.5
ENST00000591304.1
CLPTM1
cleft lip and palate associated transmembrane protein 1
chr12_-_86650045 0.35 ENST00000604798.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr2_+_68961905 0.34 ENST00000295381.3
ARHGAP25
Rho GTPase activating protein 25
chr2_-_163008903 0.34 ENST00000418842.2
ENST00000375497.3
GCG
glucagon
chr8_-_72268889 0.34 ENST00000388742.4
EYA1
eyes absent homolog 1 (Drosophila)
chr12_-_56694142 0.34 ENST00000550655.1
ENST00000548567.1
ENST00000551430.2
ENST00000351328.3
CS
citrate synthase
chr2_+_68961934 0.34 ENST00000409202.3
ARHGAP25
Rho GTPase activating protein 25
chr2_-_180610767 0.34 ENST00000409343.1
ZNF385B
zinc finger protein 385B
chr7_+_129984630 0.33 ENST00000355388.3
ENST00000497503.1
ENST00000463587.1
ENST00000461828.1
ENST00000494311.1
ENST00000466363.2
ENST00000485477.1
ENST00000431780.2
ENST00000474905.1
CPA5
carboxypeptidase A5
chr17_+_39240459 0.33 ENST00000391417.4
KRTAP4-7
keratin associated protein 4-7
chr18_+_32173276 0.33 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
DTNA
dystrobrevin, alpha
chr11_-_40315640 0.33 ENST00000278198.2
LRRC4C
leucine rich repeat containing 4C
chr1_+_209878182 0.33 ENST00000367027.3
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr15_+_93443419 0.33 ENST00000557381.1
ENST00000420239.2
CHD2
chromodomain helicase DNA binding protein 2
chr5_+_119867159 0.33 ENST00000505123.1
PRR16
proline rich 16
chr12_+_54348618 0.33 ENST00000243103.3
HOXC12
homeobox C12
chr17_-_10421853 0.32 ENST00000226207.5
MYH1
myosin, heavy chain 1, skeletal muscle, adult
chr4_+_169418255 0.32 ENST00000505667.1
ENST00000511948.1
PALLD
palladin, cytoskeletal associated protein
chr1_+_107683644 0.31 ENST00000370067.1
NTNG1
netrin G1
chr17_-_9694614 0.31 ENST00000330255.5
ENST00000571134.1
DHRS7C
dehydrogenase/reductase (SDR family) member 7C
chr3_-_52090461 0.31 ENST00000296483.6
ENST00000495880.1
DUSP7
dual specificity phosphatase 7
chr11_-_121986923 0.31 ENST00000560104.1
BLID
BH3-like motif containing, cell death inducer
chr8_-_72268968 0.31 ENST00000388740.3
EYA1
eyes absent homolog 1 (Drosophila)
chr18_-_3219847 0.30 ENST00000261606.7
MYOM1
myomesin 1
chr7_-_28220354 0.30 ENST00000283928.5
JAZF1
JAZF zinc finger 1
chr1_-_92952433 0.30 ENST00000294702.5
GFI1
growth factor independent 1 transcription repressor
chr1_-_185597619 0.30 ENST00000608417.1
ENST00000436955.1
GS1-204I12.1
GS1-204I12.1
chr6_+_31895254 0.29 ENST00000299367.5
ENST00000442278.2
C2
complement component 2
chr2_+_143635067 0.29 ENST00000264170.4
KYNU
kynureninase
chr2_+_45168875 0.29 ENST00000260653.3
SIX3
SIX homeobox 3
chr5_+_101569696 0.29 ENST00000597120.1
AC008948.1
AC008948.1
chr11_-_101000445 0.29 ENST00000534013.1
PGR
progesterone receptor
chr20_+_43990576 0.28 ENST00000372727.1
ENST00000414310.1
SYS1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr12_-_16758059 0.28 ENST00000261169.6
LMO3
LIM domain only 3 (rhombotin-like 2)
chr10_-_29923893 0.28 ENST00000355867.4
SVIL
supervillin
chr8_+_9953214 0.28 ENST00000382490.5
MSRA
methionine sulfoxide reductase A
chr3_+_185431080 0.28 ENST00000296270.1
C3orf65
chromosome 3 open reading frame 65
chr17_-_39254391 0.28 ENST00000333822.4
KRTAP4-8
keratin associated protein 4-8
chr6_-_37665751 0.28 ENST00000297153.7
ENST00000434837.3
MDGA1
MAM domain containing glycosylphosphatidylinositol anchor 1
chr6_+_41021027 0.27 ENST00000244669.2
APOBEC2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
chr8_+_9953061 0.27 ENST00000522907.1
ENST00000528246.1
MSRA
methionine sulfoxide reductase A
chr8_+_55528627 0.27 ENST00000220676.1
RP1
retinitis pigmentosa 1 (autosomal dominant)
chr3_+_130569592 0.27 ENST00000533801.2
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr5_+_59783540 0.27 ENST00000515734.2
PART1
prostate androgen-regulated transcript 1 (non-protein coding)
chr1_+_154229547 0.27 ENST00000428595.1
UBAP2L
ubiquitin associated protein 2-like
chr11_-_117747327 0.27 ENST00000584230.1
ENST00000527429.1
ENST00000584394.1
ENST00000532984.1
FXYD6
FXYD6-FXYD2
FXYD domain containing ion transport regulator 6
FXYD6-FXYD2 readthrough
chr4_-_123542224 0.27 ENST00000264497.3
IL21
interleukin 21
chr11_+_128563652 0.26 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr2_-_99871570 0.26 ENST00000333017.2
ENST00000409679.1
ENST00000423306.1
LYG2
lysozyme G-like 2
chr2_+_190541153 0.26 ENST00000313581.4
ENST00000438402.2
ENST00000431575.2
ENST00000281412.6
ANKAR
ankyrin and armadillo repeat containing
chr2_-_203735586 0.26 ENST00000454326.1
ENST00000432273.1
ENST00000450143.1
ENST00000411681.1
ICA1L
islet cell autoantigen 1,69kDa-like
chr6_-_100912785 0.26 ENST00000369208.3
SIM1
single-minded family bHLH transcription factor 1
chr12_-_53994805 0.26 ENST00000328463.7
ATF7
activating transcription factor 7
chr14_+_29236269 0.26 ENST00000313071.4
FOXG1
forkhead box G1
chr4_+_169013666 0.25 ENST00000359299.3
ANXA10
annexin A10
chr2_+_159825143 0.25 ENST00000454300.1
ENST00000263635.6
TANC1
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
chr11_-_71823266 0.25 ENST00000538919.1
ENST00000539395.1
ENST00000542531.1
ANAPC15
anaphase promoting complex subunit 15
chr9_+_44867571 0.25 ENST00000377548.2
RP11-160N1.10
RP11-160N1.10
chr7_+_148287657 0.24 ENST00000307003.2
C7orf33
chromosome 7 open reading frame 33
chr2_+_89184868 0.24 ENST00000390243.2
IGKV4-1
immunoglobulin kappa variable 4-1
chr7_-_25268104 0.24 ENST00000222674.2
NPVF
neuropeptide VF precursor

Network of associatons between targets according to the STRING database.

First level regulatory network of SHOX

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0021827 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.5 3.1 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.4 2.3 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.4 4.5 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.4 1.5 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.3 0.8 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.2 1.5 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.2 1.0 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.2 0.7 GO:1904897 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.2 1.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.2 0.5 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.2 0.9 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.2 0.9 GO:0015692 lead ion transport(GO:0015692)
0.2 1.0 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.2 0.5 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.2 0.5 GO:0045404 negative regulation of tolerance induction(GO:0002644) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.2 0.2 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.2 0.5 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.1 0.4 GO:0060166 olfactory pit development(GO:0060166)
0.1 0.4 GO:0070666 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.1 0.3 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 0.4 GO:1901993 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.1 1.0 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.8 GO:0021764 amygdala development(GO:0021764)
0.1 0.4 GO:0061743 motor learning(GO:0061743)
0.1 0.9 GO:0042997 negative regulation of low-density lipoprotein particle clearance(GO:0010989) negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.1 3.5 GO:0030728 ovulation(GO:0030728)
0.1 0.2 GO:0002384 hepatic immune response(GO:0002384)
0.1 0.3 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.1 0.3 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.1 0.9 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 0.3 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.1 0.9 GO:0014877 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.8 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.1 1.2 GO:0010917 negative regulation of mitochondrial membrane potential(GO:0010917)
0.1 7.2 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.1 1.5 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 2.0 GO:0072643 interferon-gamma secretion(GO:0072643)
0.1 1.5 GO:0021670 lateral ventricle development(GO:0021670)
0.1 0.2 GO:0014738 regulation of muscle hyperplasia(GO:0014738)
0.1 0.2 GO:0045837 negative regulation of membrane potential(GO:0045837)
0.1 0.4 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 0.4 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.1 0.5 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.1 1.8 GO:0010447 response to acidic pH(GO:0010447)
0.1 0.2 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.1 0.1 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.1 0.2 GO:0036269 swimming behavior(GO:0036269)
0.1 1.0 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 0.1 GO:0050955 thermoception(GO:0050955)
0.1 0.2 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 0.9 GO:0051639 actin filament network formation(GO:0051639)
0.1 1.2 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.6 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.0 0.4 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.0 0.1 GO:0003162 atrioventricular node development(GO:0003162)
0.0 0.3 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 1.3 GO:0043586 tongue development(GO:0043586)
0.0 0.3 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.0 0.4 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.4 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.4 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.3 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.3 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.4 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.1 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0 0.2 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.5 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.3 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.1 GO:2000854 positive regulation of corticosterone secretion(GO:2000854)
0.0 0.6 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.9 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.2 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 1.2 GO:0001919 regulation of receptor recycling(GO:0001919)
0.0 1.2 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.8 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.2 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.3 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 0.2 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 0.1 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.3 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.3 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.2 GO:0016198 axon choice point recognition(GO:0016198)
0.0 0.1 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405)
0.0 0.2 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 0.3 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.2 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 0.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.2 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.2 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.1 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.1 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316) positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.3 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.8 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.0 0.1 GO:0060490 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.0 0.5 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.2 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.0 0.6 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.3 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.2 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.1 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.4 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.1 GO:1901529 positive regulation of anion channel activity(GO:1901529)
0.0 0.6 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.2 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.2 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 1.5 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 0.5 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.2 GO:0097062 dendritic spine maintenance(GO:0097062)
0.0 0.0 GO:0071030 nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
0.0 0.2 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.1 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.4 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.3 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880)
0.0 0.1 GO:2000828 parathyroid hormone secretion(GO:0035898) post-embryonic body morphogenesis(GO:0040032) regulation of parathyroid hormone secretion(GO:2000828)
0.0 0.1 GO:0002767 immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.0 0.3 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.0 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.0 0.0 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.3 GO:0035855 megakaryocyte development(GO:0035855)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.8 GO:0036021 endolysosome lumen(GO:0036021)
0.2 3.0 GO:0033093 Weibel-Palade body(GO:0033093)
0.2 1.0 GO:1990246 uniplex complex(GO:1990246)
0.2 0.9 GO:0070826 paraferritin complex(GO:0070826)
0.2 1.5 GO:0030870 Mre11 complex(GO:0030870)
0.1 1.6 GO:0036157 outer dynein arm(GO:0036157)
0.1 0.9 GO:0014802 terminal cisterna(GO:0014802)
0.1 0.4 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.1 2.5 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 0.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.4 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.7 GO:0030897 HOPS complex(GO:0030897)
0.0 1.3 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.8 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 1.0 GO:0001891 phagocytic cup(GO:0001891)
0.0 3.3 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.2 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.3 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 1.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.6 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.1 GO:1990032 parallel fiber(GO:1990032)
0.0 0.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 1.0 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.5 GO:0032433 filopodium tip(GO:0032433)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.3 GO:0005869 dynactin complex(GO:0005869)
0.0 0.2 GO:0032584 growth cone membrane(GO:0032584)
0.0 1.2 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0035841 new growing cell tip(GO:0035841)
0.0 0.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.1 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.2 GO:0031045 dense core granule(GO:0031045)
0.0 0.2 GO:0090543 ESCRT III complex(GO:0000815) Flemming body(GO:0090543)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.8 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.2 1.7 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 0.9 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.2 0.9 GO:0015639 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.2 0.8 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.2 0.5 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.1 0.4 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.1 0.8 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.4 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.1 0.3 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 3.2 GO:0031489 myosin V binding(GO:0031489)
0.1 7.3 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 0.6 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 0.3 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 3.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.4 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.1 1.4 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 0.6 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.6 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.1 0.2 GO:0004915 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.1 0.2 GO:0098626 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.1 1.6 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 0.4 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.4 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.7 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.5 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.3 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.2 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.1 1.6 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.9 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.3 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 1.6 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.4 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.3 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.9 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.2 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 1.7 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.3 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 1.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.8 GO:0017166 vinculin binding(GO:0017166)
0.0 0.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 1.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.0 0.2 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.3 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 1.5 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.4 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.3 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.2 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 1.2 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.6 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0004803 transposase activity(GO:0004803)
0.0 0.6 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.1 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.6 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.2 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.2 GO:0031013 troponin I binding(GO:0031013)
0.0 0.3 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.2 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 2.0 GO:0005179 hormone activity(GO:0005179)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.2 GO:0005549 odorant binding(GO:0005549)
0.0 0.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 2.7 GO:0051015 actin filament binding(GO:0051015)
0.0 0.0 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.7 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.9 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 1.5 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.4 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.7 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.7 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.2 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.9 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.5 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.5 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 1.6 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.9 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 0.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.8 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 1.5 REACTOME OPSINS Genes involved in Opsins
0.1 1.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 3.1 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 1.7 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 1.5 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 0.9 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 1.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.0 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.2 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.9 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.2 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.4 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.3 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.5 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.8 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.8 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.4 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.7 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.4 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.1 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway