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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for SHOX2_HOXC5

Z-value: 0.57

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Transcription factors associated with SHOX2_HOXC5

Gene Symbol Gene ID Gene Info
SHOX2
ENSG00000168779.15 short stature homeobox 2
HOXC5
ENSG00000172789.3 homeobox C5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SHOX2hg19_v2_chr3_-_157824292_157824334-0.096.8e-01Click!
HOXC5hg19_v2_chr12_+_54426637_54426637-0.009.9e-01Click!

Activity profile of SHOX2_HOXC5 motif

Sorted Z-values of SHOX2_HOXC5 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_153552455 0.89 ENST00000392385.2
AL590867.1
Uncharacterized protein; cDNA FLJ59044, highly similar to LINE-1 reverse transcriptase homolog
chr10_+_96522361 0.80 ENST00000371321.3
CYP2C19
cytochrome P450, family 2, subfamily C, polypeptide 19
chr19_+_42212501 0.78 ENST00000398599.4
CEACAM5
carcinoembryonic antigen-related cell adhesion molecule 5
chr2_+_68872954 0.65 ENST00000394342.2
PROKR1
prokineticin receptor 1
chr9_-_21305312 0.62 ENST00000259555.4
IFNA5
interferon, alpha 5
chr11_-_46408107 0.59 ENST00000433765.2
CHRM4
cholinergic receptor, muscarinic 4
chr4_-_70080449 0.59 ENST00000446444.1
UGT2B11
UDP glucuronosyltransferase 2 family, polypeptide B11
chr6_-_52705641 0.58 ENST00000370989.2
GSTA5
glutathione S-transferase alpha 5
chr11_+_55578854 0.57 ENST00000333973.2
OR5L1
olfactory receptor, family 5, subfamily L, member 1
chr6_+_47624172 0.57 ENST00000507065.1
ENST00000296862.1
GPR111
G protein-coupled receptor 111
chrX_+_13671225 0.55 ENST00000545566.1
ENST00000544987.1
ENST00000314720.4
TCEANC
transcription elongation factor A (SII) N-terminal and central domain containing
chr19_+_42212526 0.54 ENST00000598976.1
ENST00000435837.2
ENST00000221992.6
ENST00000405816.1
CEA
CEACAM5
Uncharacterized protein
carcinoembryonic antigen-related cell adhesion molecule 5
chr17_+_39394250 0.52 ENST00000254072.6
KRTAP9-8
keratin associated protein 9-8
chr8_-_13372253 0.51 ENST00000316609.5
DLC1
deleted in liver cancer 1
chr1_-_205091115 0.50 ENST00000264515.6
ENST00000367164.1
RBBP5
retinoblastoma binding protein 5
chr6_+_28092338 0.48 ENST00000340487.4
ZSCAN16
zinc finger and SCAN domain containing 16
chr8_+_62200509 0.47 ENST00000519846.1
ENST00000518592.1
ENST00000325897.4
CLVS1
clavesin 1
chr11_+_55594695 0.47 ENST00000378397.1
OR5L2
olfactory receptor, family 5, subfamily L, member 2
chr15_-_50558223 0.45 ENST00000267845.3
HDC
histidine decarboxylase
chr19_+_52839490 0.45 ENST00000321287.8
ZNF610
zinc finger protein 610
chr12_+_82347498 0.45 ENST00000550506.1
RP11-362A1.1
RP11-362A1.1
chr14_+_22465771 0.44 ENST00000390445.2
TRAV17
T cell receptor alpha variable 17
chr19_+_52839515 0.44 ENST00000403906.3
ENST00000601151.1
ZNF610
zinc finger protein 610
chr2_+_90077680 0.43 ENST00000390270.2
IGKV3D-20
immunoglobulin kappa variable 3D-20
chr5_-_20575959 0.43 ENST00000507958.1
CDH18
cadherin 18, type 2
chr6_+_132891461 0.40 ENST00000275198.1
TAAR6
trace amine associated receptor 6
chr11_-_27722021 0.38 ENST00000356660.4
ENST00000418212.1
ENST00000533246.1
BDNF
brain-derived neurotrophic factor
chr2_-_89247338 0.37 ENST00000496168.1
IGKV1-5
immunoglobulin kappa variable 1-5
chr14_+_22670455 0.37 ENST00000390460.1
TRAV26-2
T cell receptor alpha variable 26-2
chr12_-_7281469 0.36 ENST00000542370.1
ENST00000266560.3
RBP5
retinol binding protein 5, cellular
chr8_+_105235572 0.36 ENST00000523362.1
RIMS2
regulating synaptic membrane exocytosis 2
chr4_-_138453606 0.36 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
PCDH18
protocadherin 18
chr15_-_20193370 0.36 ENST00000558565.2
IGHV3OR15-7
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr4_-_72649763 0.36 ENST00000513476.1
GC
group-specific component (vitamin D binding protein)
chr2_+_113763031 0.34 ENST00000259211.6
IL36A
interleukin 36, alpha
chr5_-_135290705 0.34 ENST00000274507.1
LECT2
leukocyte cell-derived chemotaxin 2
chr5_-_89770582 0.33 ENST00000316610.6
MBLAC2
metallo-beta-lactamase domain containing 2
chr11_+_103907308 0.33 ENST00000302259.3
DDI1
DNA-damage inducible 1 homolog 1 (S. cerevisiae)
chr22_+_21996549 0.33 ENST00000248958.4
SDF2L1
stromal cell-derived factor 2-like 1
chr18_-_19997878 0.32 ENST00000391403.2
CTAGE1
cutaneous T-cell lymphoma-associated antigen 1
chr4_-_76928641 0.32 ENST00000264888.5
CXCL9
chemokine (C-X-C motif) ligand 9
chr19_-_37663332 0.32 ENST00000392157.2
ZNF585A
zinc finger protein 585A
chr1_+_225600404 0.32 ENST00000366845.2
AC092811.1
AC092811.1
chr11_-_1643368 0.32 ENST00000399682.1
KRTAP5-4
keratin associated protein 5-4
chr15_+_75970672 0.31 ENST00000435356.1
AC105020.1
Uncharacterized protein; cDNA FLJ12988 fis, clone NT2RP3000080
chr5_-_22853429 0.31 ENST00000504376.2
CDH12
cadherin 12, type 2 (N-cadherin 2)
chr16_-_28634874 0.31 ENST00000395609.1
ENST00000350842.4
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr2_-_40006289 0.30 ENST00000260619.6
ENST00000454352.2
THUMPD2
THUMP domain containing 2
chr14_-_67878917 0.30 ENST00000216446.4
PLEK2
pleckstrin 2
chr4_+_70146217 0.29 ENST00000335568.5
ENST00000511240.1
UGT2B28
UDP glucuronosyltransferase 2 family, polypeptide B28
chr19_-_2944907 0.28 ENST00000314531.4
ZNF77
zinc finger protein 77
chr12_-_10978957 0.28 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chr19_-_58864848 0.28 ENST00000263100.3
A1BG
alpha-1-B glycoprotein
chr6_+_110501344 0.28 ENST00000368932.1
CDC40
cell division cycle 40
chr7_-_64023441 0.27 ENST00000309683.6
ZNF680
zinc finger protein 680
chr19_-_51920952 0.27 ENST00000356298.5
ENST00000339313.5
ENST00000529627.1
ENST00000439889.2
ENST00000353836.5
ENST00000432469.2
SIGLEC10
sialic acid binding Ig-like lectin 10
chrX_-_11308598 0.27 ENST00000380717.3
ARHGAP6
Rho GTPase activating protein 6
chr9_+_117373486 0.27 ENST00000288502.4
ENST00000374049.4
C9orf91
chromosome 9 open reading frame 91
chr1_-_222763101 0.27 ENST00000391883.2
ENST00000366890.1
TAF1A
TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
chr13_-_110438914 0.27 ENST00000375856.3
IRS2
insulin receptor substrate 2
chr15_-_78913628 0.26 ENST00000348639.3
CHRNA3
cholinergic receptor, nicotinic, alpha 3 (neuronal)
chr12_-_95510743 0.26 ENST00000551521.1
FGD6
FYVE, RhoGEF and PH domain containing 6
chr1_-_89357179 0.25 ENST00000448623.1
ENST00000418217.1
ENST00000370500.5
GTF2B
general transcription factor IIB
chr14_-_106494587 0.25 ENST00000390597.2
IGHV2-5
immunoglobulin heavy variable 2-5
chr2_-_99871570 0.25 ENST00000333017.2
ENST00000409679.1
ENST00000423306.1
LYG2
lysozyme G-like 2
chr14_-_54423529 0.25 ENST00000245451.4
ENST00000559087.1
BMP4
bone morphogenetic protein 4
chr11_-_95522907 0.25 ENST00000358780.5
ENST00000542135.1
FAM76B
family with sequence similarity 76, member B
chr21_-_31538971 0.25 ENST00000286808.3
CLDN17
claudin 17
chr12_+_8662057 0.24 ENST00000382064.2
CLEC4D
C-type lectin domain family 4, member D
chr2_-_89513402 0.24 ENST00000498435.1
IGKV1-27
immunoglobulin kappa variable 1-27
chr21_-_31869451 0.24 ENST00000334058.2
KRTAP19-4
keratin associated protein 19-4
chr11_+_74862032 0.24 ENST00000289575.5
ENST00000341411.4
SLCO2B1
solute carrier organic anion transporter family, member 2B1
chr14_-_106926724 0.24 ENST00000434710.1
IGHV3-43
immunoglobulin heavy variable 3-43
chr2_-_211179883 0.23 ENST00000352451.3
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr16_+_12059050 0.23 ENST00000396495.3
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr7_-_102184083 0.23 ENST00000379357.5
POLR2J3
polymerase (RNA) II (DNA directed) polypeptide J3
chr6_+_136172820 0.23 ENST00000308191.6
PDE7B
phosphodiesterase 7B
chr3_-_150690471 0.23 ENST00000468836.1
ENST00000328863.4
CLRN1
clarin 1
chr17_+_48823975 0.23 ENST00000513969.1
ENST00000503728.1
LUC7L3
LUC7-like 3 (S. cerevisiae)
chr11_-_124670550 0.23 ENST00000239614.4
MSANTD2
Myb/SANT-like DNA-binding domain containing 2
chr11_-_5323226 0.23 ENST00000380224.1
OR51B4
olfactory receptor, family 51, subfamily B, member 4
chr12_-_91573132 0.22 ENST00000550563.1
ENST00000546370.1
DCN
decorin
chr22_+_46476192 0.22 ENST00000443490.1
FLJ27365
hsa-mir-4763
chr9_-_99540328 0.22 ENST00000223428.4
ENST00000375231.1
ENST00000374641.3
ZNF510
zinc finger protein 510
chr5_-_11588907 0.22 ENST00000513598.1
ENST00000503622.1
CTNND2
catenin (cadherin-associated protein), delta 2
chr11_-_7847519 0.22 ENST00000328375.1
OR5P3
olfactory receptor, family 5, subfamily P, member 3
chr4_+_169418255 0.22 ENST00000505667.1
ENST00000511948.1
PALLD
palladin, cytoskeletal associated protein
chrX_+_52927576 0.21 ENST00000416841.2
FAM156B
family with sequence similarity 156, member B
chr19_+_35417939 0.21 ENST00000601142.1
ENST00000426813.2
ZNF30
zinc finger protein 30
chr11_+_62496114 0.21 ENST00000532583.1
TTC9C
tetratricopeptide repeat domain 9C
chr2_+_182850551 0.21 ENST00000452904.1
ENST00000409137.3
ENST00000280295.3
PPP1R1C
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr10_-_134756030 0.21 ENST00000368586.5
ENST00000368582.2
TTC40
tetratricopeptide repeat domain 40
chr4_+_95128748 0.21 ENST00000359052.4
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr21_-_31852663 0.21 ENST00000390689.2
KRTAP19-1
keratin associated protein 19-1
chr2_+_133874577 0.21 ENST00000596384.1
AC011755.1
HCG2006742; Protein LOC100996685
chr3_+_97868170 0.21 ENST00000437310.1
OR5H14
olfactory receptor, family 5, subfamily H, member 14
chr2_-_17981462 0.20 ENST00000402989.1
ENST00000428868.1
SMC6
structural maintenance of chromosomes 6
chr6_-_711395 0.20 ENST00000606285.1
RP11-532F6.3
RP11-532F6.3
chr11_+_5710919 0.20 ENST00000379965.3
ENST00000425490.1
TRIM22
tripartite motif containing 22
chr2_+_88047606 0.20 ENST00000359481.4
PLGLB2
plasminogen-like B2
chr1_-_152131703 0.20 ENST00000316073.3
RPTN
repetin
chr4_-_47916613 0.20 ENST00000381538.3
ENST00000329043.3
NFXL1
nuclear transcription factor, X-box binding-like 1
chr20_+_31870927 0.20 ENST00000253354.1
BPIFB1
BPI fold containing family B, member 1
chr2_-_89417335 0.20 ENST00000490686.1
IGKV1-17
immunoglobulin kappa variable 1-17
chr4_+_74347400 0.20 ENST00000226355.3
AFM
afamin
chr3_-_9994021 0.19 ENST00000411976.2
ENST00000412055.1
PRRT3
proline-rich transmembrane protein 3
chr13_+_77522632 0.19 ENST00000377462.1
IRG1
immunoresponsive 1 homolog (mouse)
chr5_+_140514782 0.19 ENST00000231134.5
PCDHB5
protocadherin beta 5
chr8_-_42623747 0.19 ENST00000534622.1
CHRNA6
cholinergic receptor, nicotinic, alpha 6 (neuronal)
chr19_-_51327034 0.19 ENST00000301420.2
ENST00000448701.2
KLK1
kallikrein 1
chr3_+_45927994 0.19 ENST00000357632.2
ENST00000395963.2
CCR9
chemokine (C-C motif) receptor 9
chr1_+_12851545 0.19 ENST00000332296.7
PRAMEF1
PRAME family member 1
chr11_-_95522639 0.19 ENST00000536839.1
FAM76B
family with sequence similarity 76, member B
chr2_-_87248975 0.19 ENST00000409310.2
ENST00000355705.3
PLGLB1
plasminogen-like B1
chr12_-_11214893 0.19 ENST00000533467.1
TAS2R46
taste receptor, type 2, member 46
chr6_-_89927151 0.19 ENST00000454853.2
GABRR1
gamma-aminobutyric acid (GABA) A receptor, rho 1
chr19_+_21324827 0.19 ENST00000600692.1
ENST00000599296.1
ENST00000594425.1
ENST00000311048.7
ZNF431
zinc finger protein 431
chr18_+_22040593 0.19 ENST00000256906.4
HRH4
histamine receptor H4
chr7_-_142120321 0.19 ENST00000390377.1
TRBV7-7
T cell receptor beta variable 7-7
chr5_-_70316737 0.18 ENST00000194097.4
NAIP
NLR family, apoptosis inhibitory protein
chr5_-_102898465 0.18 ENST00000507423.1
ENST00000230792.2
NUDT12
nudix (nucleoside diphosphate linked moiety X)-type motif 12
chr5_-_37835929 0.18 ENST00000381826.4
ENST00000427982.1
GDNF
glial cell derived neurotrophic factor
chr11_+_61891445 0.18 ENST00000394818.3
ENST00000533896.1
ENST00000278849.4
INCENP
inner centromere protein antigens 135/155kDa
chr2_+_90139056 0.18 ENST00000492446.1
IGKV1D-16
immunoglobulin kappa variable 1D-16
chr16_-_28621353 0.18 ENST00000567512.1
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr12_+_109785708 0.18 ENST00000310903.5
MYO1H
myosin IH
chr1_-_39339777 0.18 ENST00000397572.2
MYCBP
MYC binding protein
chr10_+_91152303 0.18 ENST00000371804.3
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr19_+_46003056 0.17 ENST00000401593.1
ENST00000396736.2
PPM1N
protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)
chr8_-_135522425 0.17 ENST00000521673.1
ZFAT
zinc finger and AT hook domain containing
chr6_+_26440700 0.17 ENST00000494393.1
ENST00000482451.1
ENST00000244519.2
ENST00000339789.4
ENST00000471353.1
ENST00000361232.3
ENST00000487627.1
ENST00000496719.1
ENST00000490254.1
ENST00000487272.1
BTN3A3
butyrophilin, subfamily 3, member A3
chr6_+_26402465 0.17 ENST00000476549.2
ENST00000289361.6
ENST00000450085.2
ENST00000425234.2
ENST00000427334.1
ENST00000506698.1
BTN3A1
butyrophilin, subfamily 3, member A1
chr17_-_3030875 0.17 ENST00000328890.2
OR1G1
olfactory receptor, family 1, subfamily G, member 1
chr11_+_5372738 0.17 ENST00000380219.1
OR51B6
olfactory receptor, family 51, subfamily B, member 6
chr1_+_70876926 0.17 ENST00000370938.3
ENST00000346806.2
CTH
cystathionase (cystathionine gamma-lyase)
chr10_-_50396407 0.17 ENST00000374153.2
ENST00000374151.3
C10orf128
chromosome 10 open reading frame 128
chr17_+_74846230 0.17 ENST00000592919.1
LINC00868
long intergenic non-protein coding RNA 868
chr6_+_110501621 0.17 ENST00000368930.1
ENST00000307731.1
CDC40
cell division cycle 40
chrX_-_15332665 0.16 ENST00000537676.1
ENST00000344384.4
ASB11
ankyrin repeat and SOCS box containing 11
chr4_-_150736962 0.16 ENST00000502345.1
ENST00000510975.1
ENST00000511993.1
RP11-526A4.1
RP11-526A4.1
chr4_-_100356551 0.16 ENST00000209665.4
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr11_-_104905840 0.16 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
CASP1
caspase 1, apoptosis-related cysteine peptidase
chr3_+_38537960 0.16 ENST00000453767.1
EXOG
endo/exonuclease (5'-3'), endonuclease G-like
chr5_-_131892501 0.16 ENST00000450655.1
IL5
interleukin 5 (colony-stimulating factor, eosinophil)
chr4_-_70518941 0.16 ENST00000286604.4
ENST00000505512.1
ENST00000514019.1
UGT2A1
UGT2A1
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
chr2_+_228736335 0.16 ENST00000440997.1
ENST00000545118.1
DAW1
dynein assembly factor with WDR repeat domains 1
chr4_-_119759795 0.16 ENST00000419654.2
SEC24D
SEC24 family member D
chr7_+_134528635 0.16 ENST00000445569.2
CALD1
caldesmon 1
chr11_-_18956556 0.16 ENST00000302797.3
MRGPRX1
MAS-related GPR, member X1
chrX_+_153533275 0.16 ENST00000426989.1
ENST00000426203.1
ENST00000369912.2
TKTL1
transketolase-like 1
chr2_-_111334678 0.16 ENST00000329516.3
ENST00000330331.5
ENST00000446930.1
RGPD6
RANBP2-like and GRIP domain containing 6
chr1_+_70876891 0.15 ENST00000411986.2
CTH
cystathionase (cystathionine gamma-lyase)
chr4_-_14889791 0.15 ENST00000509654.1
ENST00000515031.1
ENST00000505089.2
LINC00504
long intergenic non-protein coding RNA 504
chr11_+_92702886 0.15 ENST00000257068.2
ENST00000528076.1
MTNR1B
melatonin receptor 1B
chr8_+_58890917 0.15 ENST00000522992.1
RP11-1112C15.1
RP11-1112C15.1
chr3_+_156009623 0.15 ENST00000389634.5
KCNAB1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr1_+_115572415 0.15 ENST00000256592.1
TSHB
thyroid stimulating hormone, beta
chr9_-_125675576 0.15 ENST00000373659.3
ZBTB6
zinc finger and BTB domain containing 6
chr1_-_13052998 0.15 ENST00000436041.1
WI2-3308P17.2
Uncharacterized protein
chr2_+_170440844 0.15 ENST00000260970.3
ENST00000433207.1
ENST00000409714.3
ENST00000462903.1
PPIG
peptidylprolyl isomerase G (cyclophilin G)
chrX_+_100663243 0.15 ENST00000316594.5
HNRNPH2
heterogeneous nuclear ribonucleoprotein H2 (H')
chr6_+_64345698 0.15 ENST00000506783.1
ENST00000481385.2
ENST00000515594.1
ENST00000494284.2
ENST00000262043.3
PHF3
PHD finger protein 3
chr13_-_79233314 0.15 ENST00000282003.6
RNF219
ring finger protein 219
chr8_-_97273807 0.15 ENST00000517720.1
ENST00000287025.3
ENST00000523821.1
MTERFD1
MTERF domain containing 1
chr1_-_197115818 0.15 ENST00000367409.4
ENST00000294732.7
ASPM
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr19_+_49199209 0.15 ENST00000522966.1
ENST00000425340.2
ENST00000391876.4
FUT2
fucosyltransferase 2 (secretor status included)
chr12_+_64798095 0.15 ENST00000332707.5
XPOT
exportin, tRNA
chr10_+_122610687 0.14 ENST00000263461.6
WDR11
WD repeat domain 11
chr1_+_151682909 0.14 ENST00000326413.3
ENST00000442233.2
RIIAD1
AL589765.1
regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1
Uncharacterized protein; cDNA FLJ36032 fis, clone TESTI2017069
chr6_+_26124373 0.14 ENST00000377791.2
ENST00000602637.1
HIST1H2AC
histone cluster 1, H2ac
chr18_+_616672 0.14 ENST00000338387.7
CLUL1
clusterin-like 1 (retinal)
chr11_+_92085262 0.14 ENST00000298047.6
ENST00000409404.2
ENST00000541502.1
FAT3
FAT atypical cadherin 3
chr8_-_93115445 0.14 ENST00000523629.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr2_+_68962014 0.14 ENST00000467265.1
ARHGAP25
Rho GTPase activating protein 25
chr6_+_161123270 0.14 ENST00000366924.2
ENST00000308192.9
ENST00000418964.1
PLG
plasminogen
chr4_-_76944621 0.14 ENST00000306602.1
CXCL10
chemokine (C-X-C motif) ligand 10
chr2_-_225811747 0.14 ENST00000409592.3
DOCK10
dedicator of cytokinesis 10
chr11_+_124055923 0.14 ENST00000318666.6
OR10D3
olfactory receptor, family 10, subfamily D, member 3 (non-functional)
chr3_+_40518599 0.14 ENST00000314686.5
ENST00000447116.2
ENST00000429348.2
ENST00000456778.1
ZNF619
zinc finger protein 619
chr1_-_150738261 0.14 ENST00000448301.2
ENST00000368985.3
CTSS
cathepsin S
chr4_+_76481258 0.14 ENST00000311623.4
ENST00000435974.2
C4orf26
chromosome 4 open reading frame 26
chr8_+_38261880 0.14 ENST00000527175.1
LETM2
leucine zipper-EF-hand containing transmembrane protein 2
chr12_-_70093111 0.14 ENST00000548658.1
ENST00000476098.1
ENST00000331471.4
ENST00000393365.1
BEST3
bestrophin 3
chr10_+_18240814 0.14 ENST00000377374.4
SLC39A12
solute carrier family 39 (zinc transporter), member 12
chr17_-_45266542 0.14 ENST00000531206.1
ENST00000527547.1
ENST00000446365.2
ENST00000575483.1
ENST00000066544.3
CDC27
cell division cycle 27
chr10_-_102046417 0.14 ENST00000370372.2
BLOC1S2
biogenesis of lysosomal organelles complex-1, subunit 2
chr12_+_147052 0.14 ENST00000594563.1
AC026369.1
Uncharacterized protein
chr1_-_154458520 0.14 ENST00000486773.1
SHE
Src homology 2 domain containing E
chr14_+_24540046 0.14 ENST00000397016.2
ENST00000537691.1
ENST00000560356.1
ENST00000558450.1
CPNE6
copine VI (neuronal)
chr8_+_120079478 0.13 ENST00000332843.2
COLEC10
collectin sub-family member 10 (C-type lectin)
chr4_+_123653807 0.13 ENST00000314218.3
ENST00000542236.1
BBS12
Bardet-Biedl syndrome 12
chr2_+_90248739 0.13 ENST00000468879.1
IGKV1D-43
immunoglobulin kappa variable 1D-43
chr16_-_66764119 0.13 ENST00000569320.1
DYNC1LI2
dynein, cytoplasmic 1, light intermediate chain 2
chr17_-_39743139 0.13 ENST00000167586.6
KRT14
keratin 14
chr17_+_7384721 0.13 ENST00000412468.2
SLC35G6
solute carrier family 35, member G6
chr1_-_106161540 0.13 ENST00000420901.1
ENST00000610126.1
ENST00000435253.2
RP11-251P6.1
RP11-251P6.1
chr3_+_138340049 0.13 ENST00000464668.1
FAIM
Fas apoptotic inhibitory molecule
chr22_-_39190116 0.13 ENST00000406622.1
ENST00000216068.4
ENST00000406199.3
SUN2
DNAL4
Sad1 and UNC84 domain containing 2
dynein, axonemal, light chain 4
chr7_+_120591170 0.13 ENST00000431467.1
ING3
inhibitor of growth family, member 3
chr6_+_111408698 0.13 ENST00000368851.5
SLC16A10
solute carrier family 16 (aromatic amino acid transporter), member 10

Network of associatons between targets according to the STRING database.

First level regulatory network of SHOX2_HOXC5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0001694 histamine biosynthetic process(GO:0001694)
0.1 0.4 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.1 0.8 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.1 0.6 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.1 0.3 GO:0055020 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.1 0.3 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.1 0.3 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.1 0.1 GO:1903487 regulation of lactation(GO:1903487)
0.1 0.3 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.1 0.2 GO:0019364 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.1 0.2 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.1 0.2 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.1 0.2 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.1 1.5 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
0.0 0.1 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.1 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.0 0.1 GO:2001302 lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.0 0.2 GO:0002290 gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193) negative regulation of transforming growth factor-beta secretion(GO:2001202)
0.0 0.4 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.3 GO:0010748 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.0 0.2 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
0.0 0.1 GO:1902771 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.0 0.0 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.3 GO:1904798 positive regulation of core promoter binding(GO:1904798)
0.0 0.2 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.0 0.2 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.1 GO:1900158 positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.0 0.3 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.1 GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476)
0.0 0.5 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.7 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.2 GO:0021784 postganglionic parasympathetic fiber development(GO:0021784)
0.0 0.3 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.2 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.1 GO:0035513 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.7 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.1 GO:1990418 response to insulin-like growth factor stimulus(GO:1990418)
0.0 0.1 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.0 0.1 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.0 0.3 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.1 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.0 0.1 GO:0031247 actin rod assembly(GO:0031247)
0.0 0.1 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.0 0.3 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.1 GO:0061566 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.0 0.2 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.1 GO:0050705 negative regulation of interleukin-1 alpha production(GO:0032690) regulation of interleukin-1 alpha secretion(GO:0050705) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.0 0.0 GO:0050787 detoxification of mercury ion(GO:0050787)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.0 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
0.0 0.1 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.0 0.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.1 GO:0070889 platelet alpha granule organization(GO:0070889)
0.0 0.0 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.0 0.1 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.1 GO:0051102 DNA ligation involved in DNA recombination(GO:0051102)
0.0 0.1 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.0 GO:0046137 negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.2 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:0014016 neuroblast differentiation(GO:0014016)
0.0 0.1 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:0051697 protein delipidation(GO:0051697)
0.0 0.0 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.1 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.0 0.1 GO:0061358 negative regulation of Wnt protein secretion(GO:0061358)
0.0 0.2 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.2 GO:0042723 thiamine-containing compound metabolic process(GO:0042723)
0.0 0.1 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.1 GO:1990180 mitochondrial tRNA 3'-end processing(GO:1990180)
0.0 0.0 GO:0006711 estrogen catabolic process(GO:0006711)
0.0 0.2 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.1 GO:0002399 MHC class II protein complex assembly(GO:0002399)
0.0 0.2 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:0051311 meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
0.0 0.2 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.2 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.1 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.0 0.1 GO:0039650 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.0 0.2 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.1 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.1 GO:0061743 motor learning(GO:0061743)
0.0 0.3 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.0 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.0 0.2 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.0 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.1 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.1 GO:0050893 sensory processing(GO:0050893)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.2 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.3 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 1.5 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.1 GO:0019249 lactate biosynthetic process(GO:0019249)
0.0 0.1 GO:0034144 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)
0.0 0.0 GO:0042214 terpene metabolic process(GO:0042214)
0.0 0.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.1 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.0 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.0 0.1 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.0 0.1 GO:1902572 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
0.0 0.0 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.1 GO:0072233 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.0 0.1 GO:0015801 aromatic amino acid transport(GO:0015801)
0.0 0.1 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 0.1 GO:0051661 maintenance of centrosome location(GO:0051661)
0.0 0.1 GO:0042262 DNA protection(GO:0042262)
0.0 0.3 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0003095 pressure natriuresis(GO:0003095)
0.0 0.1 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.7 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.1 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.1 GO:0060406 positive regulation of penile erection(GO:0060406)
0.0 0.1 GO:0090237 regulation of arachidonic acid secretion(GO:0090237) positive regulation of arachidonic acid secretion(GO:0090238)
0.0 0.0 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.0 0.2 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.1 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885)
0.0 0.1 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.1 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.4 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.0 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
0.0 0.2 GO:0060539 diaphragm development(GO:0060539)
0.0 0.1 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 1.0 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.1 GO:0006004 fucose metabolic process(GO:0006004)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.5 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.2 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.2 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.3 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.1 GO:0018444 translation release factor complex(GO:0018444)
0.0 0.3 GO:0034464 BBSome(GO:0034464)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.1 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.1 GO:0005607 laminin-2 complex(GO:0005607)
0.0 0.2 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.3 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.2 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.2 GO:0044279 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.0 0.1 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0005715 late recombination nodule(GO:0005715)
0.0 0.1 GO:0097196 Shu complex(GO:0097196)
0.0 0.1 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.2 GO:0000801 central element(GO:0000801)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.1 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 0.6 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.1 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.0 GO:0048787 presynaptic active zone membrane(GO:0048787) synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.1 GO:0032807 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0030123 AP-3 adaptor complex(GO:0030123)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 GO:0034235 GPI anchor binding(GO:0034235)
0.1 0.4 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.1 0.7 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.1 0.7 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.1 0.5 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.6 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 0.5 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.5 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 1.3 GO:0005549 odorant binding(GO:0005549)
0.1 0.3 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.2 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.1 0.3 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.1 0.2 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 0.3 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.2 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.1 GO:0047977 hepoxilin-epoxide hydrolase activity(GO:0047977)
0.0 0.2 GO:0030107 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
0.0 0.7 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0031862 prostanoid receptor binding(GO:0031862)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.9 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.2 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.0 0.2 GO:0004802 transketolase activity(GO:0004802)
0.0 0.1 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.2 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.2 GO:0070404 NADH binding(GO:0070404)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.1 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.0 0.1 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.1 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.1 GO:0031783 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.0 0.1 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 0.1 GO:0004803 transposase activity(GO:0004803)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.2 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.1 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.0 0.1 GO:0070538 oleic acid binding(GO:0070538)
0.0 0.1 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.0 0.1 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.1 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.0 0.1 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.3 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.2 GO:1990405 protein antigen binding(GO:1990405)
0.0 0.1 GO:0004979 beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047)
0.0 0.1 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.2 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.1 GO:0030614 oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
0.0 0.1 GO:0070568 guanylyltransferase activity(GO:0070568)
0.0 0.1 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.1 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.6 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0004040 amidase activity(GO:0004040)
0.0 0.3 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.1 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.0 0.3 GO:0019841 retinol binding(GO:0019841)
0.0 0.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.4 GO:0043495 protein anchor(GO:0043495)
0.0 0.2 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.1 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.0 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.0 0.1 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.1 GO:0035473 lipase binding(GO:0035473)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.3 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.0 GO:1903135 cupric ion binding(GO:1903135)
0.0 0.0 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.1 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.3 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.2 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.0 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.0 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.3 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.0 GO:0099609 microtubule lateral binding(GO:0099609)
0.0 0.0 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.0 0.5 GO:0004364 glutathione transferase activity(GO:0004364)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.2 PID IL5 PATHWAY IL5-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 1.0 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.4 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.6 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.6 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.2 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation