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Inflammatory response time course, HUVEC (Wada et al., 2009)
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Results for SIX5_SMARCC2_HCFC1
Z-value: 2.49
Motif logo
Transcription factors associated with SIX5_SMARCC2_HCFC1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
SIX5
|
ENSG00000177045.6 | SIX homeobox 5 |
|
SMARCC2
|
ENSG00000139613.7 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2 |
|
HCFC1
|
ENSG00000172534.9 | host cell factor C1 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| SMARCC2 | hg19_v2_chr12_-_56583332_56583369 | 0.52 | 7.1e-03 | Click! |
| HCFC1 | hg19_v2_chrX_-_153236819_153236978, hg19_v2_chrX_-_153236620_153236684, hg19_v2_chrX_-_153237258_153237295 | -0.25 | 2.4e-01 | Click! |
| SIX5 | hg19_v2_chr19_-_46272462_46272562 | -0.14 | 5.1e-01 | Click! |
Activity profile of SIX5_SMARCC2_HCFC1 motif
Sorted Z-values of SIX5_SMARCC2_HCFC1 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of SIX5_SMARCC2_HCFC1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.0 | 11.9 | GO:0033499 | galactose catabolic process via UDP-galactose(GO:0033499) |
| 2.6 | 7.7 | GO:1902846 | regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846) |
| 1.7 | 8.6 | GO:0051697 | protein delipidation(GO:0051697) |
| 1.6 | 7.8 | GO:2001106 | regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106) |
| 1.3 | 3.9 | GO:0090283 | regulation of protein glycosylation in Golgi(GO:0090283) |
| 1.2 | 5.9 | GO:0019075 | virus maturation(GO:0019075) |
| 1.1 | 6.6 | GO:0044878 | mitotic cytokinesis checkpoint(GO:0044878) |
| 1.0 | 2.9 | GO:1990569 | UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569) |
| 0.9 | 2.8 | GO:0035494 | SNARE complex disassembly(GO:0035494) |
| 0.9 | 2.8 | GO:0051596 | methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727) |
| 0.9 | 3.7 | GO:0032053 | ciliary basal body organization(GO:0032053) |
| 0.8 | 2.4 | GO:1903926 | signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926) |
| 0.8 | 2.4 | GO:1900195 | positive regulation of oocyte maturation(GO:1900195) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777) |
| 0.8 | 3.9 | GO:0033384 | geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337) |
| 0.7 | 4.4 | GO:0032483 | regulation of Rab protein signal transduction(GO:0032483) |
| 0.7 | 4.4 | GO:0006574 | valine catabolic process(GO:0006574) |
| 0.7 | 5.4 | GO:0031914 | negative regulation of synaptic plasticity(GO:0031914) |
| 0.6 | 1.9 | GO:0007037 | vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830) |
| 0.6 | 3.9 | GO:0036111 | very long-chain fatty-acyl-CoA metabolic process(GO:0036111) |
| 0.6 | 17.8 | GO:0043101 | purine-containing compound salvage(GO:0043101) |
| 0.6 | 3.1 | GO:0071460 | cellular response to cell-matrix adhesion(GO:0071460) |
| 0.6 | 1.8 | GO:0048633 | positive regulation of skeletal muscle tissue growth(GO:0048633) |
| 0.6 | 2.4 | GO:0090038 | negative regulation of protein kinase C signaling(GO:0090038) |
| 0.6 | 1.7 | GO:0045897 | positive regulation of transcription during mitosis(GO:0045897) |
| 0.6 | 7.4 | GO:0035269 | protein O-linked mannosylation(GO:0035269) |
| 0.6 | 13.8 | GO:0016180 | snRNA processing(GO:0016180) |
| 0.5 | 1.6 | GO:1905166 | negative regulation of protein catabolic process in the vacuole(GO:1904351) negative regulation of lysosomal protein catabolic process(GO:1905166) |
| 0.5 | 5.4 | GO:0061469 | regulation of type B pancreatic cell proliferation(GO:0061469) |
| 0.5 | 2.7 | GO:0019464 | glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464) |
| 0.5 | 1.6 | GO:0006742 | NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364) |
| 0.5 | 3.2 | GO:0032380 | regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383) |
| 0.5 | 2.0 | GO:0035948 | positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) histone H4-K12 acetylation(GO:0043983) |
| 0.5 | 6.5 | GO:0000733 | DNA strand renaturation(GO:0000733) |
| 0.5 | 4.2 | GO:0030174 | regulation of DNA-dependent DNA replication initiation(GO:0030174) |
| 0.4 | 3.7 | GO:0015781 | pyrimidine nucleotide-sugar transport(GO:0015781) |
| 0.4 | 3.6 | GO:0051013 | microtubule severing(GO:0051013) |
| 0.4 | 2.0 | GO:0044565 | dendritic cell proliferation(GO:0044565) |
| 0.4 | 1.2 | GO:1903625 | negative regulation of DNA catabolic process(GO:1903625) |
| 0.4 | 1.2 | GO:2001045 | closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045) |
| 0.4 | 1.5 | GO:0050653 | chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653) |
| 0.4 | 3.7 | GO:0051388 | positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) |
| 0.4 | 4.4 | GO:0044597 | polyketide metabolic process(GO:0030638) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598) |
| 0.4 | 3.2 | GO:0097033 | respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033) |
| 0.4 | 6.0 | GO:0030213 | hyaluronan biosynthetic process(GO:0030213) |
| 0.4 | 5.3 | GO:0036481 | intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036481) |
| 0.3 | 20.3 | GO:0032784 | regulation of DNA-templated transcription, elongation(GO:0032784) |
| 0.3 | 1.0 | GO:1902299 | pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) regulation of chromatin silencing at telomere(GO:0031938) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299) |
| 0.3 | 6.7 | GO:0035563 | positive regulation of chromatin binding(GO:0035563) |
| 0.3 | 1.0 | GO:0044806 | G-quadruplex DNA unwinding(GO:0044806) |
| 0.3 | 2.5 | GO:1902035 | positive regulation of hematopoietic stem cell proliferation(GO:1902035) |
| 0.3 | 1.2 | GO:0042350 | GDP-L-fucose biosynthetic process(GO:0042350) |
| 0.3 | 0.3 | GO:0036090 | cleavage furrow ingression(GO:0036090) |
| 0.3 | 0.8 | GO:0007497 | posterior midgut development(GO:0007497) endothelin receptor signaling pathway(GO:0086100) |
| 0.3 | 2.2 | GO:0050689 | negative regulation of defense response to virus by host(GO:0050689) |
| 0.3 | 1.6 | GO:1902774 | late endosome to lysosome transport(GO:1902774) |
| 0.3 | 0.8 | GO:1904579 | response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579) |
| 0.3 | 4.5 | GO:0045008 | depyrimidination(GO:0045008) |
| 0.3 | 2.1 | GO:0070092 | regulation of glucagon secretion(GO:0070092) |
| 0.3 | 0.8 | GO:0043137 | DNA replication, removal of RNA primer(GO:0043137) |
| 0.2 | 2.0 | GO:0006572 | tyrosine catabolic process(GO:0006572) |
| 0.2 | 2.7 | GO:0072383 | plus-end-directed vesicle transport along microtubule(GO:0072383) |
| 0.2 | 1.6 | GO:0097428 | protein maturation by iron-sulfur cluster transfer(GO:0097428) |
| 0.2 | 0.9 | GO:0023016 | signal transduction by trans-phosphorylation(GO:0023016) |
| 0.2 | 1.4 | GO:0090166 | Golgi disassembly(GO:0090166) |
| 0.2 | 2.2 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
| 0.2 | 4.3 | GO:1902894 | negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894) |
| 0.2 | 0.7 | GO:0072708 | response to sorbitol(GO:0072708) cellular response to sorbitol(GO:0072709) |
| 0.2 | 1.2 | GO:1990822 | regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822) |
| 0.2 | 1.2 | GO:0070272 | proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272) |
| 0.2 | 2.1 | GO:0051597 | response to methylmercury(GO:0051597) |
| 0.2 | 0.9 | GO:2000312 | regulation of kainate selective glutamate receptor activity(GO:2000312) |
| 0.2 | 4.3 | GO:0006744 | ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663) |
| 0.2 | 0.7 | GO:0006172 | ADP biosynthetic process(GO:0006172) purine deoxyribonucleotide biosynthetic process(GO:0009153) purine deoxyribonucleoside diphosphate biosynthetic process(GO:0009183) |
| 0.2 | 7.3 | GO:0021522 | spinal cord motor neuron differentiation(GO:0021522) |
| 0.2 | 0.5 | GO:0035668 | TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669) |
| 0.2 | 0.5 | GO:0035621 | ER to Golgi ceramide transport(GO:0035621) |
| 0.2 | 1.7 | GO:0035562 | negative regulation of chromatin binding(GO:0035562) |
| 0.2 | 2.0 | GO:0006930 | substrate-dependent cell migration, cell extension(GO:0006930) |
| 0.2 | 1.7 | GO:0006777 | Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) |
| 0.2 | 3.7 | GO:0003215 | cardiac right ventricle morphogenesis(GO:0003215) |
| 0.2 | 0.9 | GO:0006269 | DNA replication, synthesis of RNA primer(GO:0006269) |
| 0.2 | 2.5 | GO:0033539 | fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539) |
| 0.2 | 2.1 | GO:2000766 | negative regulation of cytoplasmic translation(GO:2000766) |
| 0.2 | 1.4 | GO:1902746 | regulation of lens fiber cell differentiation(GO:1902746) |
| 0.2 | 1.4 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
| 0.1 | 0.7 | GO:0006285 | base-excision repair, AP site formation(GO:0006285) |
| 0.1 | 0.4 | GO:1903336 | intralumenal vesicle formation(GO:0070676) negative regulation of vacuolar transport(GO:1903336) |
| 0.1 | 0.6 | GO:0006663 | platelet activating factor biosynthetic process(GO:0006663) |
| 0.1 | 0.6 | GO:0009644 | response to high light intensity(GO:0009644) |
| 0.1 | 0.3 | GO:0006751 | glutathione catabolic process(GO:0006751) |
| 0.1 | 1.4 | GO:0030263 | apoptotic chromosome condensation(GO:0030263) |
| 0.1 | 5.9 | GO:0042407 | cristae formation(GO:0042407) |
| 0.1 | 1.1 | GO:0050859 | negative regulation of B cell receptor signaling pathway(GO:0050859) |
| 0.1 | 0.5 | GO:0009438 | methylglyoxal metabolic process(GO:0009438) |
| 0.1 | 0.4 | GO:0070510 | regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512) |
| 0.1 | 5.2 | GO:0006284 | base-excision repair(GO:0006284) |
| 0.1 | 2.0 | GO:0046951 | ketone body biosynthetic process(GO:0046951) |
| 0.1 | 0.7 | GO:1905098 | negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098) |
| 0.1 | 0.4 | GO:0043000 | Golgi to plasma membrane CFTR protein transport(GO:0043000) |
| 0.1 | 0.8 | GO:1990481 | mRNA pseudouridine synthesis(GO:1990481) |
| 0.1 | 0.4 | GO:0048627 | myoblast development(GO:0048627) |
| 0.1 | 0.5 | GO:0051562 | negative regulation of mitochondrial calcium ion concentration(GO:0051562) |
| 0.1 | 1.6 | GO:0035721 | intraciliary retrograde transport(GO:0035721) |
| 0.1 | 0.4 | GO:0093001 | glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001) |
| 0.1 | 1.2 | GO:0097113 | AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688) |
| 0.1 | 0.4 | GO:0000354 | cis assembly of pre-catalytic spliceosome(GO:0000354) |
| 0.1 | 0.3 | GO:1902024 | histidine transport(GO:0015817) L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024) |
| 0.1 | 2.3 | GO:0097034 | mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034) |
| 0.1 | 1.4 | GO:0039530 | MDA-5 signaling pathway(GO:0039530) |
| 0.1 | 0.9 | GO:0042760 | very long-chain fatty acid catabolic process(GO:0042760) |
| 0.1 | 1.1 | GO:0098734 | macromolecule depalmitoylation(GO:0098734) |
| 0.1 | 0.4 | GO:0070966 | nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) |
| 0.1 | 0.4 | GO:2001153 | regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153) |
| 0.1 | 0.5 | GO:0044208 | 'de novo' AMP biosynthetic process(GO:0044208) |
| 0.1 | 0.3 | GO:0090675 | intermicrovillar adhesion(GO:0090675) |
| 0.1 | 0.9 | GO:0045716 | positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716) |
| 0.1 | 1.3 | GO:0030916 | otic vesicle formation(GO:0030916) |
| 0.1 | 0.5 | GO:0008063 | Toll signaling pathway(GO:0008063) |
| 0.1 | 1.3 | GO:0000463 | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) |
| 0.1 | 1.5 | GO:1902018 | negative regulation of cilium assembly(GO:1902018) |
| 0.1 | 0.1 | GO:1902990 | mitotic telomere maintenance via semi-conservative replication(GO:1902990) |
| 0.1 | 4.2 | GO:0042572 | retinol metabolic process(GO:0042572) |
| 0.1 | 1.1 | GO:0019388 | galactose catabolic process(GO:0019388) |
| 0.1 | 3.0 | GO:0042994 | cytoplasmic sequestering of transcription factor(GO:0042994) |
| 0.1 | 0.3 | GO:0032203 | telomere formation via telomerase(GO:0032203) |
| 0.1 | 0.4 | GO:1903691 | positive regulation of wound healing, spreading of epidermal cells(GO:1903691) |
| 0.1 | 1.3 | GO:0006449 | regulation of translational termination(GO:0006449) |
| 0.1 | 2.7 | GO:2000369 | regulation of clathrin-mediated endocytosis(GO:2000369) |
| 0.1 | 2.4 | GO:0046856 | phosphatidylinositol dephosphorylation(GO:0046856) |
| 0.1 | 1.0 | GO:0051001 | negative regulation of nitric-oxide synthase activity(GO:0051001) |
| 0.1 | 0.3 | GO:0061357 | positive regulation of Wnt protein secretion(GO:0061357) |
| 0.1 | 3.8 | GO:0090503 | RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503) |
| 0.1 | 2.3 | GO:0070935 | 3'-UTR-mediated mRNA stabilization(GO:0070935) |
| 0.1 | 1.9 | GO:0043568 | positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568) |
| 0.1 | 0.5 | GO:0016557 | peroxisome membrane biogenesis(GO:0016557) |
| 0.1 | 1.7 | GO:0045116 | protein neddylation(GO:0045116) |
| 0.1 | 2.0 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
| 0.1 | 2.7 | GO:1904030 | negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030) |
| 0.1 | 0.8 | GO:0016446 | somatic hypermutation of immunoglobulin genes(GO:0016446) |
| 0.1 | 0.2 | GO:1903348 | positive regulation of bicellular tight junction assembly(GO:1903348) |
| 0.1 | 0.3 | GO:0001189 | RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189) |
| 0.1 | 1.0 | GO:0022417 | protein maturation by protein folding(GO:0022417) |
| 0.1 | 0.5 | GO:0030242 | pexophagy(GO:0030242) |
| 0.1 | 1.4 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
| 0.1 | 5.9 | GO:0042771 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771) |
| 0.1 | 0.6 | GO:0002329 | pre-B cell differentiation(GO:0002329) |
| 0.1 | 0.4 | GO:0048312 | intracellular distribution of mitochondria(GO:0048312) |
| 0.1 | 0.5 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
| 0.1 | 0.6 | GO:0034351 | regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351) |
| 0.1 | 0.3 | GO:1902268 | negative regulation of polyamine transmembrane transport(GO:1902268) |
| 0.1 | 0.1 | GO:0016075 | rRNA catabolic process(GO:0016075) |
| 0.1 | 0.2 | GO:1900063 | regulation of peroxisome organization(GO:1900063) |
| 0.1 | 0.3 | GO:1902775 | mitochondrial large ribosomal subunit assembly(GO:1902775) |
| 0.1 | 0.5 | GO:0010265 | SCF complex assembly(GO:0010265) |
| 0.1 | 4.1 | GO:0000186 | activation of MAPKK activity(GO:0000186) |
| 0.1 | 0.2 | GO:0042796 | snRNA transcription from RNA polymerase III promoter(GO:0042796) |
| 0.1 | 1.0 | GO:0032802 | low-density lipoprotein particle receptor catabolic process(GO:0032802) |
| 0.1 | 1.6 | GO:0019370 | leukotriene biosynthetic process(GO:0019370) |
| 0.1 | 0.6 | GO:0035865 | cellular response to potassium ion(GO:0035865) |
| 0.1 | 0.4 | GO:2000503 | positive regulation of natural killer cell chemotaxis(GO:2000503) |
| 0.1 | 0.3 | GO:0010624 | regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626) |
| 0.1 | 0.7 | GO:0006048 | UDP-N-acetylglucosamine biosynthetic process(GO:0006048) |
| 0.1 | 0.7 | GO:1900028 | negative regulation of ruffle assembly(GO:1900028) |
| 0.1 | 1.8 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.1 | 2.7 | GO:0006654 | phosphatidic acid biosynthetic process(GO:0006654) |
| 0.1 | 4.5 | GO:0032981 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
| 0.1 | 0.4 | GO:0051725 | protein de-ADP-ribosylation(GO:0051725) |
| 0.1 | 0.9 | GO:0007175 | negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) |
| 0.1 | 0.6 | GO:0030422 | production of siRNA involved in RNA interference(GO:0030422) |
| 0.0 | 0.4 | GO:0017185 | peptidyl-lysine hydroxylation(GO:0017185) |
| 0.0 | 0.9 | GO:0001682 | tRNA 5'-leader removal(GO:0001682) |
| 0.0 | 1.7 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
| 0.0 | 0.4 | GO:0090168 | Golgi reassembly(GO:0090168) |
| 0.0 | 0.6 | GO:0001767 | establishment of lymphocyte polarity(GO:0001767) |
| 0.0 | 0.2 | GO:0072344 | rescue of stalled ribosome(GO:0072344) |
| 0.0 | 0.3 | GO:2000270 | negative regulation of fibroblast apoptotic process(GO:2000270) |
| 0.0 | 0.2 | GO:0006121 | mitochondrial electron transport, succinate to ubiquinone(GO:0006121) |
| 0.0 | 0.4 | GO:0072178 | nephric duct morphogenesis(GO:0072178) |
| 0.0 | 6.0 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
| 0.0 | 0.4 | GO:0048050 | post-embryonic eye morphogenesis(GO:0048050) |
| 0.0 | 6.0 | GO:0045333 | cellular respiration(GO:0045333) |
| 0.0 | 1.3 | GO:1900087 | positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) |
| 0.0 | 0.3 | GO:0051103 | DNA ligation involved in DNA repair(GO:0051103) |
| 0.0 | 0.2 | GO:0071494 | cellular response to UV-C(GO:0071494) |
| 0.0 | 0.1 | GO:0071922 | establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922) |
| 0.0 | 0.5 | GO:0021670 | lateral ventricle development(GO:0021670) |
| 0.0 | 0.4 | GO:0018214 | peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214) |
| 0.0 | 0.3 | GO:0016255 | attachment of GPI anchor to protein(GO:0016255) |
| 0.0 | 0.3 | GO:0015793 | glycerol transport(GO:0015793) |
| 0.0 | 2.0 | GO:0015949 | nucleobase-containing small molecule interconversion(GO:0015949) |
| 0.0 | 0.4 | GO:0060211 | regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) |
| 0.0 | 1.5 | GO:0017145 | stem cell division(GO:0017145) |
| 0.0 | 0.3 | GO:0051415 | interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418) |
| 0.0 | 0.3 | GO:0006002 | fructose 6-phosphate metabolic process(GO:0006002) |
| 0.0 | 0.2 | GO:0072321 | chaperone-mediated protein transport(GO:0072321) |
| 0.0 | 0.5 | GO:0006271 | DNA strand elongation involved in DNA replication(GO:0006271) |
| 0.0 | 0.3 | GO:0051694 | pointed-end actin filament capping(GO:0051694) |
| 0.0 | 0.5 | GO:0009086 | methionine biosynthetic process(GO:0009086) |
| 0.0 | 0.3 | GO:0007000 | nucleolus organization(GO:0007000) |
| 0.0 | 0.6 | GO:0006293 | nucleotide-excision repair, preincision complex stabilization(GO:0006293) |
| 0.0 | 2.9 | GO:0048207 | vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) |
| 0.0 | 0.0 | GO:1990414 | replication-born double-strand break repair via sister chromatid exchange(GO:1990414) |
| 0.0 | 1.1 | GO:0001893 | maternal placenta development(GO:0001893) |
| 0.0 | 0.2 | GO:0019264 | glycine biosynthetic process from serine(GO:0019264) |
| 0.0 | 0.4 | GO:0048227 | plasma membrane to endosome transport(GO:0048227) |
| 0.0 | 0.1 | GO:0031392 | regulation of prostaglandin biosynthetic process(GO:0031392) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) |
| 0.0 | 2.7 | GO:0033275 | muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275) |
| 0.0 | 0.5 | GO:0071305 | cellular response to vitamin D(GO:0071305) |
| 0.0 | 0.5 | GO:0033234 | negative regulation of protein sumoylation(GO:0033234) |
| 0.0 | 0.2 | GO:0060741 | prostate gland stromal morphogenesis(GO:0060741) |
| 0.0 | 1.1 | GO:1903861 | positive regulation of dendrite extension(GO:1903861) |
| 0.0 | 0.5 | GO:1903504 | regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504) |
| 0.0 | 0.7 | GO:2000772 | regulation of cellular senescence(GO:2000772) |
| 0.0 | 1.4 | GO:0043550 | regulation of lipid kinase activity(GO:0043550) |
| 0.0 | 0.1 | GO:0042851 | L-alanine metabolic process(GO:0042851) L-alanine catabolic process(GO:0042853) |
| 0.0 | 0.2 | GO:0034628 | nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628) |
| 0.0 | 0.5 | GO:1902230 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230) |
| 0.0 | 4.3 | GO:0001764 | neuron migration(GO:0001764) |
| 0.0 | 1.7 | GO:0007040 | lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171) |
| 0.0 | 0.3 | GO:0000098 | sulfur amino acid catabolic process(GO:0000098) |
| 0.0 | 0.2 | GO:0033299 | secretion of lysosomal enzymes(GO:0033299) |
| 0.0 | 0.1 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
| 0.0 | 0.4 | GO:0030575 | nuclear body organization(GO:0030575) |
| 0.0 | 1.6 | GO:0035914 | skeletal muscle cell differentiation(GO:0035914) |
| 0.0 | 0.1 | GO:0034224 | cellular response to zinc ion starvation(GO:0034224) G1 to G0 transition involved in cell differentiation(GO:0070315) |
| 0.0 | 0.3 | GO:0033119 | negative regulation of RNA splicing(GO:0033119) |
| 0.0 | 0.2 | GO:2000042 | negative regulation of double-strand break repair via homologous recombination(GO:2000042) |
| 0.0 | 0.9 | GO:0033146 | regulation of intracellular estrogen receptor signaling pathway(GO:0033146) |
| 0.0 | 0.1 | GO:0043129 | surfactant homeostasis(GO:0043129) |
| 0.0 | 0.8 | GO:0072332 | intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332) |
| 0.0 | 0.3 | GO:0051085 | chaperone mediated protein folding requiring cofactor(GO:0051085) |
| 0.0 | 0.3 | GO:1901661 | quinone metabolic process(GO:1901661) |
| 0.0 | 0.3 | GO:0098792 | xenophagy(GO:0098792) |
| 0.0 | 0.0 | GO:1990785 | response to water-immersion restraint stress(GO:1990785) |
| 0.0 | 2.3 | GO:0007030 | Golgi organization(GO:0007030) |
| 0.0 | 0.4 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
| 0.0 | 0.2 | GO:0035999 | tetrahydrofolate interconversion(GO:0035999) |
| 0.0 | 0.4 | GO:0045948 | positive regulation of translational initiation(GO:0045948) |
| 0.0 | 0.4 | GO:0045022 | early endosome to late endosome transport(GO:0045022) |
| 0.0 | 0.4 | GO:0010390 | histone monoubiquitination(GO:0010390) |
| 0.0 | 0.1 | GO:0046836 | glycolipid transport(GO:0046836) |
| 0.0 | 0.1 | GO:0046909 | intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445) |
| 0.0 | 0.0 | GO:1904938 | dopaminergic neuron axon guidance(GO:0036514) chemorepulsion of dopaminergic neuron axon(GO:0036518) planar cell polarity pathway involved in axon guidance(GO:1904938) |
| 0.0 | 0.2 | GO:0051457 | maintenance of protein location in nucleus(GO:0051457) |
| 0.0 | 0.4 | GO:0051412 | response to corticosterone(GO:0051412) |
| 0.0 | 0.2 | GO:0033540 | fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540) |
| 0.0 | 0.3 | GO:0009642 | response to light intensity(GO:0009642) |
| 0.0 | 0.0 | GO:0072364 | regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter(GO:0072364) |
| 0.0 | 0.4 | GO:0050858 | negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) |
| 0.0 | 0.1 | GO:0060576 | intestinal epithelial cell development(GO:0060576) |
| 0.0 | 0.2 | GO:0048681 | negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571) |
| 0.0 | 2.1 | GO:0050729 | positive regulation of inflammatory response(GO:0050729) |
| 0.0 | 2.0 | GO:0021987 | cerebral cortex development(GO:0021987) |
| 0.0 | 0.1 | GO:0006987 | activation of signaling protein activity involved in unfolded protein response(GO:0006987) |
| 0.0 | 0.1 | GO:1900864 | mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864) |
| 0.0 | 0.1 | GO:0010756 | positive regulation of plasminogen activation(GO:0010756) |
| 0.0 | 0.1 | GO:0036500 | ATF6-mediated unfolded protein response(GO:0036500) |
| 0.0 | 0.1 | GO:1904526 | regulation of microtubule binding(GO:1904526) |
| 0.0 | 0.1 | GO:0030037 | actin filament reorganization involved in cell cycle(GO:0030037) |
| 0.0 | 0.8 | GO:0035307 | positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307) |
| 0.0 | 0.1 | GO:0071376 | response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376) |
| 0.0 | 0.0 | GO:0032286 | central nervous system myelin maintenance(GO:0032286) |
| 0.0 | 1.2 | GO:0000245 | spliceosomal complex assembly(GO:0000245) |
| 0.0 | 0.1 | GO:0061042 | vascular wound healing(GO:0061042) |
| 0.0 | 1.2 | GO:0048024 | regulation of mRNA splicing, via spliceosome(GO:0048024) |
| 0.0 | 0.7 | GO:0043392 | negative regulation of DNA binding(GO:0043392) |
| 0.0 | 0.2 | GO:1904355 | positive regulation of telomere capping(GO:1904355) |
| 0.0 | 0.1 | GO:0000056 | ribosomal small subunit export from nucleus(GO:0000056) |
| 0.0 | 0.1 | GO:0071847 | TNFSF11-mediated signaling pathway(GO:0071847) |
| 0.0 | 0.3 | GO:0060416 | response to growth hormone(GO:0060416) |
| 0.0 | 0.2 | GO:0060444 | branching involved in mammary gland duct morphogenesis(GO:0060444) |
| 0.0 | 0.1 | GO:0015705 | iodide transport(GO:0015705) |
| 0.0 | 0.4 | GO:0035115 | embryonic forelimb morphogenesis(GO:0035115) |
| 0.0 | 0.4 | GO:0030318 | melanocyte differentiation(GO:0030318) |
| 0.0 | 0.7 | GO:0006904 | vesicle docking involved in exocytosis(GO:0006904) |
| 0.0 | 1.5 | GO:0022617 | extracellular matrix disassembly(GO:0022617) |
| 0.0 | 0.2 | GO:0042420 | dopamine catabolic process(GO:0042420) |
| 0.0 | 0.3 | GO:0070536 | protein K63-linked deubiquitination(GO:0070536) |
| 0.0 | 0.1 | GO:0007258 | JUN phosphorylation(GO:0007258) |
| 0.0 | 0.1 | GO:0018206 | peptidyl-methionine modification(GO:0018206) |
| 0.0 | 0.0 | GO:1901298 | regulation of hydrogen peroxide-mediated programmed cell death(GO:1901298) |
| 0.0 | 0.6 | GO:0006446 | regulation of translational initiation(GO:0006446) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.0 | 17.8 | GO:1902560 | GMP reductase complex(GO:1902560) |
| 2.6 | 7.7 | GO:0055028 | cortical microtubule(GO:0055028) |
| 1.4 | 5.4 | GO:0016533 | cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533) |
| 1.1 | 14.6 | GO:0032039 | integrator complex(GO:0032039) |
| 0.9 | 7.1 | GO:0098560 | cytoplasmic side of late endosome membrane(GO:0098560) |
| 0.7 | 2.2 | GO:0071006 | U2-type catalytic step 1 spliceosome(GO:0071006) |
| 0.7 | 3.9 | GO:0005797 | Golgi medial cisterna(GO:0005797) |
| 0.6 | 1.7 | GO:0019008 | molybdopterin synthase complex(GO:0019008) |
| 0.5 | 4.6 | GO:0071986 | Ragulator complex(GO:0071986) |
| 0.4 | 5.9 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 0.4 | 1.6 | GO:0031166 | integral component of vacuolar membrane(GO:0031166) |
| 0.4 | 2.4 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
| 0.4 | 3.2 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
| 0.4 | 2.2 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
| 0.4 | 1.1 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
| 0.4 | 2.5 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
| 0.3 | 4.9 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
| 0.3 | 19.7 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.3 | 1.0 | GO:0036387 | nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387) |
| 0.3 | 1.3 | GO:0005683 | U7 snRNP(GO:0005683) |
| 0.3 | 2.5 | GO:0061617 | MICOS complex(GO:0061617) |
| 0.3 | 2.4 | GO:0001940 | male pronucleus(GO:0001940) |
| 0.3 | 1.1 | GO:0071012 | catalytic step 1 spliceosome(GO:0071012) |
| 0.3 | 1.4 | GO:0009368 | endopeptidase Clp complex(GO:0009368) |
| 0.3 | 3.2 | GO:0045275 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
| 0.3 | 3.1 | GO:0070652 | HAUS complex(GO:0070652) |
| 0.2 | 3.9 | GO:0035102 | PRC1 complex(GO:0035102) |
| 0.2 | 7.8 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.2 | 0.9 | GO:0042721 | mitochondrial inner membrane protein insertion complex(GO:0042721) |
| 0.2 | 3.4 | GO:0030008 | TRAPP complex(GO:0030008) |
| 0.2 | 0.6 | GO:0033185 | dolichol-phosphate-mannose synthase complex(GO:0033185) |
| 0.2 | 0.6 | GO:0000438 | core TFIIH complex portion of holo TFIIH complex(GO:0000438) |
| 0.2 | 4.4 | GO:0033270 | paranode region of axon(GO:0033270) |
| 0.2 | 1.4 | GO:1990130 | Iml1 complex(GO:1990130) |
| 0.2 | 0.6 | GO:0097598 | sperm cytoplasmic droplet(GO:0097598) |
| 0.2 | 6.9 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
| 0.2 | 2.2 | GO:0035068 | micro-ribonucleoprotein complex(GO:0035068) |
| 0.1 | 0.6 | GO:0098803 | respiratory chain complex(GO:0098803) |
| 0.1 | 0.9 | GO:0033263 | CORVET complex(GO:0033263) |
| 0.1 | 3.4 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
| 0.1 | 1.0 | GO:0070545 | PeBoW complex(GO:0070545) |
| 0.1 | 2.4 | GO:0016461 | unconventional myosin complex(GO:0016461) |
| 0.1 | 1.1 | GO:0032389 | MutLalpha complex(GO:0032389) |
| 0.1 | 0.6 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
| 0.1 | 0.6 | GO:0005879 | axonemal microtubule(GO:0005879) |
| 0.1 | 3.8 | GO:0031011 | Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202) |
| 0.1 | 0.8 | GO:0000172 | ribonuclease MRP complex(GO:0000172) |
| 0.1 | 2.0 | GO:0030914 | STAGA complex(GO:0030914) |
| 0.1 | 2.0 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
| 0.1 | 0.7 | GO:0097165 | nuclear stress granule(GO:0097165) |
| 0.1 | 0.6 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 0.1 | 0.4 | GO:0031436 | BRCA1-BARD1 complex(GO:0031436) |
| 0.1 | 1.2 | GO:0098839 | postsynaptic density membrane(GO:0098839) |
| 0.1 | 9.8 | GO:0032154 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.1 | 1.5 | GO:0090543 | Flemming body(GO:0090543) |
| 0.1 | 1.8 | GO:0097539 | ciliary transition fiber(GO:0097539) |
| 0.1 | 0.9 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
| 0.1 | 1.6 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.1 | 0.3 | GO:0097224 | sperm connecting piece(GO:0097224) |
| 0.1 | 5.5 | GO:0031907 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.1 | 1.4 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.1 | 1.3 | GO:0005753 | mitochondrial proton-transporting ATP synthase complex(GO:0005753) |
| 0.1 | 2.5 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
| 0.1 | 0.6 | GO:0071203 | WASH complex(GO:0071203) |
| 0.1 | 4.5 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.1 | 0.6 | GO:0031313 | extrinsic component of endosome membrane(GO:0031313) |
| 0.1 | 0.4 | GO:0005945 | 6-phosphofructokinase complex(GO:0005945) |
| 0.1 | 5.2 | GO:0031201 | SNARE complex(GO:0031201) |
| 0.1 | 0.3 | GO:0042765 | GPI-anchor transamidase complex(GO:0042765) |
| 0.1 | 0.5 | GO:0070552 | BRISC complex(GO:0070552) |
| 0.1 | 0.6 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
| 0.1 | 0.4 | GO:0032009 | early phagosome(GO:0032009) |
| 0.1 | 0.6 | GO:0060091 | kinocilium(GO:0060091) |
| 0.1 | 0.2 | GO:0070876 | SOSS complex(GO:0070876) |
| 0.1 | 0.3 | GO:0089717 | spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717) |
| 0.1 | 0.4 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
| 0.1 | 0.8 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
| 0.1 | 7.8 | GO:1990204 | oxidoreductase complex(GO:1990204) |
| 0.1 | 3.1 | GO:0098798 | mitochondrial protein complex(GO:0098798) |
| 0.1 | 0.3 | GO:0030678 | mitochondrial ribonuclease P complex(GO:0030678) |
| 0.1 | 0.2 | GO:0070939 | Dsl1p complex(GO:0070939) |
| 0.1 | 4.8 | GO:0043195 | terminal bouton(GO:0043195) |
| 0.1 | 0.2 | GO:0005686 | U2 snRNP(GO:0005686) |
| 0.1 | 4.5 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.1 | 0.4 | GO:0033503 | HULC complex(GO:0033503) |
| 0.1 | 1.6 | GO:0035869 | ciliary transition zone(GO:0035869) |
| 0.0 | 1.0 | GO:0030122 | AP-2 adaptor complex(GO:0030122) |
| 0.0 | 1.2 | GO:0071682 | endocytic vesicle lumen(GO:0071682) |
| 0.0 | 0.6 | GO:0043220 | Schmidt-Lanterman incisure(GO:0043220) |
| 0.0 | 4.4 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
| 0.0 | 0.7 | GO:0031083 | BLOC-1 complex(GO:0031083) |
| 0.0 | 0.3 | GO:0000931 | gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274) |
| 0.0 | 3.6 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 0.4 | GO:0030897 | HOPS complex(GO:0030897) |
| 0.0 | 0.2 | GO:0097179 | protease inhibitor complex(GO:0097179) |
| 0.0 | 0.1 | GO:0071159 | NF-kappaB complex(GO:0071159) |
| 0.0 | 5.5 | GO:0000781 | chromosome, telomeric region(GO:0000781) |
| 0.0 | 0.4 | GO:0044666 | MLL3/4 complex(GO:0044666) |
| 0.0 | 1.7 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.0 | 1.7 | GO:0005844 | polysome(GO:0005844) |
| 0.0 | 0.2 | GO:0061689 | tricellular tight junction(GO:0061689) |
| 0.0 | 0.3 | GO:0070938 | contractile ring(GO:0070938) |
| 0.0 | 3.7 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.0 | 0.3 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 0.0 | 1.2 | GO:0097542 | ciliary tip(GO:0097542) |
| 0.0 | 0.4 | GO:0000177 | cytoplasmic exosome (RNase complex)(GO:0000177) |
| 0.0 | 0.2 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
| 0.0 | 11.7 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.0 | 3.7 | GO:0001650 | fibrillar center(GO:0001650) |
| 0.0 | 0.7 | GO:0030057 | desmosome(GO:0030057) |
| 0.0 | 0.1 | GO:0043224 | nuclear SCF ubiquitin ligase complex(GO:0043224) |
| 0.0 | 0.2 | GO:0035253 | ciliary rootlet(GO:0035253) |
| 0.0 | 0.4 | GO:0005779 | integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231) |
| 0.0 | 0.8 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.0 | 0.1 | GO:0000439 | core TFIIH complex(GO:0000439) |
| 0.0 | 0.1 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
| 0.0 | 0.1 | GO:0016589 | NURF complex(GO:0016589) |
| 0.0 | 0.2 | GO:0030904 | retromer complex(GO:0030904) |
| 0.0 | 0.3 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
| 0.0 | 1.4 | GO:0000118 | histone deacetylase complex(GO:0000118) |
| 0.0 | 0.0 | GO:0005687 | U4 snRNP(GO:0005687) |
| 0.0 | 0.7 | GO:0002102 | podosome(GO:0002102) |
| 0.0 | 0.2 | GO:0097512 | cardiac myofibril(GO:0097512) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.0 | 17.8 | GO:0016657 | GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657) |
| 1.5 | 4.4 | GO:0003955 | NAD(P)H dehydrogenase (quinone) activity(GO:0003955) 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025) |
| 1.4 | 5.7 | GO:0097363 | protein O-GlcNAc transferase activity(GO:0097363) |
| 1.0 | 3.1 | GO:0008534 | oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534) |
| 1.0 | 2.9 | GO:0005462 | UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462) |
| 0.9 | 2.8 | GO:0005483 | soluble NSF attachment protein activity(GO:0005483) |
| 0.9 | 2.8 | GO:0004416 | hydroxyacylglutathione hydrolase activity(GO:0004416) |
| 0.8 | 2.4 | GO:0034739 | histone deacetylase activity (H4-K16 specific)(GO:0034739) |
| 0.8 | 3.9 | GO:0004337 | dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337) |
| 0.8 | 2.3 | GO:0016649 | electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649) |
| 0.7 | 2.2 | GO:0030626 | U12 snRNA binding(GO:0030626) |
| 0.7 | 5.6 | GO:0000403 | Y-form DNA binding(GO:0000403) |
| 0.7 | 2.7 | GO:0004047 | aminomethyltransferase activity(GO:0004047) |
| 0.6 | 3.9 | GO:0033989 | 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594) |
| 0.6 | 1.9 | GO:0003858 | 3-hydroxybutyrate dehydrogenase activity(GO:0003858) |
| 0.6 | 1.9 | GO:0052642 | lysophosphatidic acid phosphatase activity(GO:0052642) |
| 0.6 | 11.9 | GO:0016857 | racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857) |
| 0.6 | 9.3 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
| 0.6 | 4.3 | GO:0048039 | ubiquinone binding(GO:0048039) |
| 0.6 | 6.5 | GO:0036310 | annealing helicase activity(GO:0036310) |
| 0.5 | 5.4 | GO:0005176 | ErbB-2 class receptor binding(GO:0005176) |
| 0.5 | 6.5 | GO:0003720 | telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964) |
| 0.5 | 3.7 | GO:0015165 | pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165) |
| 0.5 | 1.5 | GO:0008955 | peptidoglycan glycosyltransferase activity(GO:0008955) |
| 0.5 | 3.6 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
| 0.5 | 3.2 | GO:0016681 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
| 0.4 | 0.4 | GO:0000702 | oxidized base lesion DNA N-glycosylase activity(GO:0000702) |
| 0.4 | 2.1 | GO:0016634 | oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634) |
| 0.4 | 1.2 | GO:0031812 | G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812) |
| 0.4 | 2.0 | GO:0010484 | H3 histone acetyltransferase activity(GO:0010484) |
| 0.4 | 6.0 | GO:0043225 | anion transmembrane-transporting ATPase activity(GO:0043225) |
| 0.3 | 1.4 | GO:0004809 | tRNA (guanine-N2-)-methyltransferase activity(GO:0004809) |
| 0.3 | 1.4 | GO:0031493 | nucleosomal histone binding(GO:0031493) |
| 0.3 | 6.5 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.3 | 6.1 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
| 0.3 | 1.6 | GO:0035529 | NADH pyrophosphatase activity(GO:0035529) |
| 0.3 | 1.3 | GO:0071209 | U7 snRNA binding(GO:0071209) |
| 0.3 | 0.9 | GO:0050252 | retinol O-fatty-acyltransferase activity(GO:0050252) |
| 0.3 | 1.4 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
| 0.3 | 0.8 | GO:0004962 | endothelin receptor activity(GO:0004962) |
| 0.3 | 1.6 | GO:1903135 | cupric ion binding(GO:1903135) |
| 0.3 | 2.4 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
| 0.3 | 1.1 | GO:0004169 | dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169) |
| 0.2 | 4.7 | GO:0003995 | acyl-CoA dehydrogenase activity(GO:0003995) |
| 0.2 | 0.9 | GO:0003896 | DNA primase activity(GO:0003896) |
| 0.2 | 2.8 | GO:0052658 | inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) |
| 0.2 | 1.6 | GO:0004301 | epoxide hydrolase activity(GO:0004301) |
| 0.2 | 0.6 | GO:0004582 | dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582) |
| 0.2 | 2.2 | GO:0070883 | pre-miRNA binding(GO:0070883) |
| 0.2 | 9.2 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
| 0.2 | 1.2 | GO:0072542 | protein phosphatase activator activity(GO:0072542) |
| 0.2 | 0.6 | GO:0047192 | 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192) |
| 0.2 | 0.7 | GO:0032408 | MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408) |
| 0.2 | 4.1 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
| 0.2 | 1.7 | GO:0003847 | 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847) |
| 0.2 | 2.6 | GO:0035612 | AP-2 adaptor complex binding(GO:0035612) |
| 0.2 | 0.5 | GO:0008798 | beta-aspartyl-peptidase activity(GO:0008798) |
| 0.2 | 0.5 | GO:0004019 | adenylosuccinate synthase activity(GO:0004019) |
| 0.2 | 1.8 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
| 0.2 | 1.1 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
| 0.2 | 1.9 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
| 0.2 | 2.7 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
| 0.1 | 1.6 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
| 0.1 | 4.6 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.1 | 0.4 | GO:0004711 | ribosomal protein S6 kinase activity(GO:0004711) |
| 0.1 | 1.0 | GO:0016671 | oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671) |
| 0.1 | 1.8 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 0.1 | 0.9 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
| 0.1 | 3.6 | GO:0005123 | death receptor binding(GO:0005123) |
| 0.1 | 1.1 | GO:0008474 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
| 0.1 | 1.6 | GO:0015174 | basic amino acid transmembrane transporter activity(GO:0015174) |
| 0.1 | 0.5 | GO:0004699 | calcium-independent protein kinase C activity(GO:0004699) |
| 0.1 | 1.9 | GO:0046527 | glucosyltransferase activity(GO:0046527) |
| 0.1 | 1.1 | GO:0001042 | RNA polymerase I core binding(GO:0001042) |
| 0.1 | 0.8 | GO:0008079 | translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079) |
| 0.1 | 0.3 | GO:0003839 | gamma-glutamylcyclotransferase activity(GO:0003839) |
| 0.1 | 1.3 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 0.1 | 2.1 | GO:0017160 | Ral GTPase binding(GO:0017160) |
| 0.1 | 2.7 | GO:0015035 | protein disulfide oxidoreductase activity(GO:0015035) |
| 0.1 | 0.5 | GO:0097001 | ceramide binding(GO:0097001) |
| 0.1 | 0.7 | GO:0003960 | NADPH:quinone reductase activity(GO:0003960) |
| 0.1 | 0.7 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
| 0.1 | 0.4 | GO:0004698 | calcium-dependent protein kinase C activity(GO:0004698) |
| 0.1 | 0.2 | GO:0030272 | 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272) |
| 0.1 | 0.9 | GO:0047498 | calcium-dependent phospholipase A2 activity(GO:0047498) |
| 0.1 | 0.5 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
| 0.1 | 0.5 | GO:0004013 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.1 | 0.2 | GO:0019166 | trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166) |
| 0.1 | 0.9 | GO:0015266 | protein channel activity(GO:0015266) |
| 0.1 | 2.1 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.1 | 0.4 | GO:0005006 | epidermal growth factor-activated receptor activity(GO:0005006) |
| 0.1 | 3.2 | GO:0015248 | sterol transporter activity(GO:0015248) |
| 0.1 | 1.0 | GO:0043138 | 3'-5' DNA helicase activity(GO:0043138) |
| 0.1 | 0.3 | GO:0003923 | GPI-anchor transamidase activity(GO:0003923) |
| 0.1 | 0.3 | GO:0015254 | glycerol channel activity(GO:0015254) |
| 0.1 | 0.7 | GO:0070569 | uridylyltransferase activity(GO:0070569) |
| 0.1 | 3.0 | GO:0000175 | 3'-5'-exoribonuclease activity(GO:0000175) |
| 0.1 | 13.7 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.1 | 0.5 | GO:0051998 | carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998) |
| 0.1 | 1.0 | GO:0004551 | nucleotide diphosphatase activity(GO:0004551) |
| 0.1 | 0.2 | GO:0032038 | myosin II heavy chain binding(GO:0032038) |
| 0.1 | 0.3 | GO:0008073 | ornithine decarboxylase inhibitor activity(GO:0008073) |
| 0.1 | 1.0 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.1 | 0.4 | GO:0003872 | 6-phosphofructokinase activity(GO:0003872) |
| 0.1 | 0.3 | GO:0042285 | UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285) |
| 0.1 | 1.9 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
| 0.1 | 4.0 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.1 | 2.1 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 0.1 | 0.5 | GO:0008172 | S-methyltransferase activity(GO:0008172) |
| 0.1 | 0.8 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.1 | 0.9 | GO:0004526 | ribonuclease P activity(GO:0004526) |
| 0.1 | 0.3 | GO:0044378 | non-sequence-specific DNA binding, bending(GO:0044378) |
| 0.1 | 0.4 | GO:0016300 | tRNA (uracil) methyltransferase activity(GO:0016300) |
| 0.1 | 1.0 | GO:0019104 | DNA N-glycosylase activity(GO:0019104) |
| 0.1 | 2.0 | GO:0051539 | 4 iron, 4 sulfur cluster binding(GO:0051539) |
| 0.1 | 0.1 | GO:0032138 | DNA insertion or deletion binding(GO:0032135) single base insertion or deletion binding(GO:0032138) |
| 0.1 | 0.3 | GO:0032089 | NACHT domain binding(GO:0032089) |
| 0.1 | 0.6 | GO:0004697 | protein kinase C activity(GO:0004697) |
| 0.1 | 3.2 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.1 | 1.2 | GO:0070742 | C2H2 zinc finger domain binding(GO:0070742) |
| 0.1 | 0.2 | GO:0035241 | protein-arginine omega-N monomethyltransferase activity(GO:0035241) |
| 0.1 | 1.8 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.1 | 0.9 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
| 0.1 | 5.9 | GO:0032947 | protein complex scaffold(GO:0032947) |
| 0.1 | 1.2 | GO:0008569 | ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) |
| 0.0 | 1.0 | GO:0035613 | RNA stem-loop binding(GO:0035613) |
| 0.0 | 0.8 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 0.0 | 3.7 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.0 | 0.3 | GO:0008273 | calcium, potassium:sodium antiporter activity(GO:0008273) |
| 0.0 | 0.1 | GO:0005136 | interleukin-4 receptor binding(GO:0005136) |
| 0.0 | 10.5 | GO:0008234 | cysteine-type peptidase activity(GO:0008234) |
| 0.0 | 1.2 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
| 0.0 | 0.3 | GO:0050733 | RS domain binding(GO:0050733) |
| 0.0 | 0.7 | GO:0004017 | adenylate kinase activity(GO:0004017) |
| 0.0 | 3.2 | GO:0035064 | methylated histone binding(GO:0035064) |
| 0.0 | 5.3 | GO:0016811 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811) |
| 0.0 | 0.1 | GO:0003985 | acetyl-CoA C-acetyltransferase activity(GO:0003985) |
| 0.0 | 0.3 | GO:0016595 | glutamate binding(GO:0016595) |
| 0.0 | 2.6 | GO:0051287 | NAD binding(GO:0051287) |
| 0.0 | 0.7 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
| 0.0 | 1.5 | GO:0016627 | oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627) |
| 0.0 | 3.5 | GO:0003730 | mRNA 3'-UTR binding(GO:0003730) |
| 0.0 | 1.7 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
| 0.0 | 0.2 | GO:0008732 | glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732) |
| 0.0 | 1.3 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.0 | 0.7 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
| 0.0 | 0.7 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
| 0.0 | 0.4 | GO:0019213 | deacetylase activity(GO:0019213) |
| 0.0 | 0.5 | GO:0045125 | bioactive lipid receptor activity(GO:0045125) |
| 0.0 | 86.3 | GO:0003677 | DNA binding(GO:0003677) |
| 0.0 | 0.2 | GO:0004447 | iodide peroxidase activity(GO:0004447) |
| 0.0 | 0.4 | GO:0005522 | profilin binding(GO:0005522) |
| 0.0 | 0.4 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
| 0.0 | 0.5 | GO:0005537 | mannose binding(GO:0005537) |
| 0.0 | 0.2 | GO:0000309 | nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515) |
| 0.0 | 0.4 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 0.0 | 0.8 | GO:0070003 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 0.0 | 1.1 | GO:0035255 | ionotropic glutamate receptor binding(GO:0035255) |
| 0.0 | 0.2 | GO:0089720 | caspase binding(GO:0089720) |
| 0.0 | 0.8 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.0 | 0.5 | GO:0000062 | fatty-acyl-CoA binding(GO:0000062) |
| 0.0 | 0.6 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.0 | 2.1 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.0 | 0.2 | GO:0008131 | primary amine oxidase activity(GO:0008131) |
| 0.0 | 0.3 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 0.0 | 0.1 | GO:0051139 | metal ion:proton antiporter activity(GO:0051139) |
| 0.0 | 2.1 | GO:0019905 | syntaxin binding(GO:0019905) |
| 0.0 | 0.4 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.0 | 4.0 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.0 | 0.1 | GO:0015056 | corticotrophin-releasing factor receptor activity(GO:0015056) |
| 0.0 | 0.2 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.0 | 0.6 | GO:0000149 | SNARE binding(GO:0000149) |
| 0.0 | 0.2 | GO:0070034 | telomerase RNA binding(GO:0070034) |
| 0.0 | 0.2 | GO:0001103 | RNA polymerase II repressing transcription factor binding(GO:0001103) |
| 0.0 | 1.3 | GO:0003714 | transcription corepressor activity(GO:0003714) |
| 0.0 | 1.5 | GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553) |
| 0.0 | 0.5 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.0 | 0.3 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.0 | 1.1 | GO:0035591 | signaling adaptor activity(GO:0035591) |
| 0.0 | 0.4 | GO:0046875 | ephrin receptor binding(GO:0046875) |
| 0.0 | 0.3 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 10.5 | PID P53 REGULATION PATHWAY | p53 pathway |
| 0.1 | 5.2 | PID REELIN PATHWAY | Reelin signaling pathway |
| 0.1 | 11.3 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.1 | 9.0 | PID E2F PATHWAY | E2F transcription factor network |
| 0.1 | 1.3 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.1 | 2.4 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.1 | 2.0 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.1 | 3.7 | ST JNK MAPK PATHWAY | JNK MAPK Pathway |
| 0.0 | 4.4 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.0 | 1.1 | ST GA12 PATHWAY | G alpha 12 Pathway |
| 0.0 | 1.8 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.0 | 0.7 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
| 0.0 | 2.1 | PID ARF6 PATHWAY | Arf6 signaling events |
| 0.0 | 2.2 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.0 | 0.9 | PID BARD1 PATHWAY | BARD1 signaling events |
| 0.0 | 1.7 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.0 | 0.5 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
| 0.0 | 0.2 | PID PDGFRA PATHWAY | PDGFR-alpha signaling pathway |
| 0.0 | 1.8 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 0.0 | 0.6 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.0 | 0.4 | PID EPHRINB REV PATHWAY | Ephrin B reverse signaling |
| 0.0 | 0.6 | PID NEPHRIN NEPH1 PATHWAY | Nephrin/Neph1 signaling in the kidney podocyte |
| 0.0 | 0.8 | PID ARF6 TRAFFICKING PATHWAY | Arf6 trafficking events |
| 0.0 | 0.5 | PID RHODOPSIN PATHWAY | Visual signal transduction: Rods |
| 0.0 | 0.7 | PID TRKR PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 17.8 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 0.4 | 7.7 | REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES | Genes involved in Recruitment of NuMA to mitotic centrosomes |
| 0.3 | 6.0 | REACTOME HYALURONAN METABOLISM | Genes involved in Hyaluronan metabolism |
| 0.2 | 4.3 | REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
| 0.2 | 3.9 | REACTOME ALPHA LINOLENIC ACID ALA METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |
| 0.2 | 4.5 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.2 | 1.8 | REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
| 0.2 | 2.4 | REACTOME G2 M DNA DAMAGE CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
| 0.1 | 3.4 | REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
| 0.1 | 7.3 | REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
| 0.1 | 2.2 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 0.1 | 3.9 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.1 | 1.7 | REACTOME NOTCH HLH TRANSCRIPTION PATHWAY | Genes involved in Notch-HLH transcription pathway |
| 0.1 | 1.9 | REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 | Genes involved in Signaling by activated point mutants of FGFR1 |
| 0.1 | 5.6 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.1 | 4.4 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 0.1 | 5.4 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.1 | 0.9 | REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 | Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1 |
| 0.1 | 1.3 | REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
| 0.1 | 1.7 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 0.1 | 6.8 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 0.1 | 2.1 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 0.1 | 1.4 | REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY | Genes involved in TRAF3-dependent IRF activation pathway |
| 0.1 | 2.4 | REACTOME SYNTHESIS OF PA | Genes involved in Synthesis of PA |
| 0.1 | 29.6 | REACTOME GENERIC TRANSCRIPTION PATHWAY | Genes involved in Generic Transcription Pathway |
| 0.1 | 1.3 | REACTOME FANCONI ANEMIA PATHWAY | Genes involved in Fanconi Anemia pathway |
| 0.1 | 1.1 | REACTOME PROLACTIN RECEPTOR SIGNALING | Genes involved in Prolactin receptor signaling |
| 0.1 | 1.6 | REACTOME MICRORNA MIRNA BIOGENESIS | Genes involved in MicroRNA (miRNA) Biogenesis |
| 0.0 | 3.0 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.0 | 1.6 | REACTOME MHC CLASS II ANTIGEN PRESENTATION | Genes involved in MHC class II antigen presentation |
| 0.0 | 0.6 | REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES | Genes involved in p75NTR recruits signalling complexes |
| 0.0 | 0.7 | REACTOME SIGNALING BY NOTCH1 | Genes involved in Signaling by NOTCH1 |
| 0.0 | 0.6 | REACTOME ACYL CHAIN REMODELLING OF PC | Genes involved in Acyl chain remodelling of PC |
| 0.0 | 1.3 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.0 | 0.6 | REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX | Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex |
| 0.0 | 1.0 | REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS | Genes involved in Trafficking of GluR2-containing AMPA receptors |
| 0.0 | 1.0 | REACTOME ENOS ACTIVATION AND REGULATION | Genes involved in eNOS activation and regulation |
| 0.0 | 1.2 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
| 0.0 | 0.5 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.0 | 0.7 | REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION | Genes involved in activated TAK1 mediates p38 MAPK activation |
| 0.0 | 1.0 | REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS | Genes involved in Post-translational modification: synthesis of GPI-anchored proteins |
| 0.0 | 0.3 | REACTOME PASSIVE TRANSPORT BY AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.0 | 0.6 | REACTOME PHOSPHORYLATION OF THE APC C | Genes involved in Phosphorylation of the APC/C |
| 0.0 | 4.9 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.0 | 0.5 | REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 | Genes involved in Regulation of AMPK activity via LKB1 |
| 0.0 | 0.5 | REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
| 0.0 | 1.4 | REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM | Genes involved in Transport of Mature Transcript to Cytoplasm |
| 0.0 | 0.5 | REACTOME DAG AND IP3 SIGNALING | Genes involved in DAG and IP3 signaling |
| 0.0 | 0.4 | REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
| 0.0 | 1.6 | REACTOME TRANS GOLGI NETWORK VESICLE BUDDING | Genes involved in trans-Golgi Network Vesicle Budding |
| 0.0 | 0.7 | REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D | Genes involved in Metabolism of steroid hormones and vitamins A and D |
| 0.0 | 0.5 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.0 | 0.7 | REACTOME PPARA ACTIVATES GENE EXPRESSION | Genes involved in PPARA Activates Gene Expression |
| 0.0 | 0.3 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.0 | 0.5 | REACTOME PYRIMIDINE METABOLISM | Genes involved in Pyrimidine metabolism |
| 0.0 | 0.5 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.0 | 0.1 | REACTOME ENDOGENOUS STEROLS | Genes involved in Endogenous sterols |
| 0.0 | 0.1 | REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 | Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 |
| 0.0 | 0.2 | REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Norepinephrine Neurotransmitter Release Cycle |