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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for SIX6

Z-value: 0.54

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Transcription factors associated with SIX6

Gene Symbol Gene ID Gene Info
SIX6
ENSG00000184302.6 SIX homeobox 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SIX6hg19_v2_chr14_+_60975644_60975673-0.154.7e-01Click!

Activity profile of SIX6 motif

Sorted Z-values of SIX6 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_8543533 1.70 ENST00000454244.1
LMCD1
LIM and cysteine-rich domains 1
chr3_+_8543393 0.94 ENST00000157600.3
ENST00000415597.1
ENST00000535732.1
LMCD1
LIM and cysteine-rich domains 1
chr3_+_8543561 0.82 ENST00000397386.3
LMCD1
LIM and cysteine-rich domains 1
chr8_+_84824920 0.71 ENST00000523678.1
RP11-120I21.2
RP11-120I21.2
chr3_+_151531810 0.70 ENST00000232892.7
AADAC
arylacetamide deacetylase
chr14_+_21525981 0.41 ENST00000308227.2
RNASE8
ribonuclease, RNase A family, 8
chr13_+_34392200 0.40 ENST00000434425.1
RFC3
replication factor C (activator 1) 3, 38kDa
chr15_+_58430368 0.37 ENST00000558772.1
ENST00000219919.4
AQP9
aquaporin 9
chr15_+_58430567 0.36 ENST00000536493.1
AQP9
aquaporin 9
chr1_-_161015752 0.35 ENST00000435396.1
ENST00000368021.3
USF1
upstream transcription factor 1
chr1_+_156119798 0.35 ENST00000355014.2
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr18_-_69246167 0.33 ENST00000566582.1
RP11-510D19.1
RP11-510D19.1
chr6_+_26240561 0.33 ENST00000377745.2
HIST1H4F
histone cluster 1, H4f
chr2_+_210636697 0.32 ENST00000439458.1
ENST00000272845.6
UNC80
unc-80 homolog (C. elegans)
chr12_+_117348742 0.30 ENST00000309909.5
ENST00000455858.2
FBXW8
F-box and WD repeat domain containing 8
chr3_-_9994021 0.29 ENST00000411976.2
ENST00000412055.1
PRRT3
proline-rich transmembrane protein 3
chr14_+_20937538 0.29 ENST00000361505.5
ENST00000553591.1
PNP
purine nucleoside phosphorylase
chr1_-_20446020 0.28 ENST00000375105.3
PLA2G2D
phospholipase A2, group IID
chr13_-_46679185 0.25 ENST00000439329.3
CPB2
carboxypeptidase B2 (plasma)
chr9_-_21351377 0.24 ENST00000380210.1
IFNA6
interferon, alpha 6
chr1_+_86934526 0.24 ENST00000394711.1
CLCA1
chloride channel accessory 1
chr12_-_121477039 0.23 ENST00000257570.5
OASL
2'-5'-oligoadenylate synthetase-like
chr1_-_65468148 0.23 ENST00000415842.1
RP11-182I10.3
RP11-182I10.3
chr1_+_31885963 0.22 ENST00000373709.3
SERINC2
serine incorporator 2
chr4_+_74301880 0.22 ENST00000395792.2
ENST00000226359.2
AFP
alpha-fetoprotein
chr13_-_46679144 0.21 ENST00000181383.4
CPB2
carboxypeptidase B2 (plasma)
chr12_-_122018859 0.21 ENST00000536437.1
ENST00000377071.4
ENST00000538046.2
KDM2B
lysine (K)-specific demethylase 2B
chr6_+_26204825 0.21 ENST00000360441.4
HIST1H4E
histone cluster 1, H4e
chrX_+_12809463 0.21 ENST00000380663.3
ENST00000380668.5
ENST00000398491.2
ENST00000489404.1
PRPS2
phosphoribosyl pyrophosphate synthetase 2
chr22_-_17702729 0.20 ENST00000449907.2
ENST00000441548.1
ENST00000399839.1
CECR1
cat eye syndrome chromosome region, candidate 1
chr10_+_52094298 0.20 ENST00000595931.1
AC069547.1
HCG1745369; PRO3073; Uncharacterized protein
chr15_-_80263506 0.20 ENST00000335661.6
BCL2A1
BCL2-related protein A1
chr1_+_156119466 0.19 ENST00000414683.1
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr1_-_182369751 0.19 ENST00000367565.1
TEDDM1
transmembrane epididymal protein 1
chr1_-_67142710 0.19 ENST00000502413.2
AL139147.1
Uncharacterized protein
chr12_-_14849470 0.18 ENST00000261170.3
GUCY2C
guanylate cyclase 2C (heat stable enterotoxin receptor)
chr4_+_88532028 0.18 ENST00000282478.7
DSPP
dentin sialophosphoprotein
chr10_+_81891416 0.17 ENST00000372270.2
PLAC9
placenta-specific 9
chr6_+_127898312 0.16 ENST00000329722.7
C6orf58
chromosome 6 open reading frame 58
chr2_-_208989225 0.15 ENST00000264376.4
CRYGD
crystallin, gamma D
chr4_+_113739244 0.15 ENST00000503271.1
ENST00000503423.1
ENST00000506722.1
ANK2
ankyrin 2, neuronal
chr21_-_43735446 0.15 ENST00000398431.2
TFF3
trefoil factor 3 (intestinal)
chrX_+_64708615 0.15 ENST00000338957.4
ENST00000423889.3
ZC3H12B
zinc finger CCCH-type containing 12B
chr12_-_121476959 0.14 ENST00000339275.5
OASL
2'-5'-oligoadenylate synthetase-like
chrX_+_8433376 0.14 ENST00000440654.2
ENST00000381029.4
VCX3B
variable charge, X-linked 3B
chr1_+_40942887 0.14 ENST00000372706.1
ZFP69
ZFP69 zinc finger protein
chr12_-_121476750 0.14 ENST00000543677.1
OASL
2'-5'-oligoadenylate synthetase-like
chrX_-_77225135 0.14 ENST00000458128.1
PGAM4
phosphoglycerate mutase family member 4
chr7_-_141957847 0.13 ENST00000552471.1
ENST00000547058.2
PRSS58
protease, serine, 58
chr11_-_104972158 0.13 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
CASP1
CARD16
CARD17
caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr9_-_100707116 0.13 ENST00000259456.3
HEMGN
hemogen
chr6_-_8102279 0.13 ENST00000488226.2
EEF1E1
eukaryotic translation elongation factor 1 epsilon 1
chr4_-_123377880 0.13 ENST00000226730.4
IL2
interleukin 2
chr1_+_160709029 0.12 ENST00000444090.2
ENST00000441662.2
SLAMF7
SLAM family member 7
chr10_-_61720640 0.12 ENST00000521074.1
ENST00000444900.1
C10orf40
chromosome 10 open reading frame 40
chr4_-_155511887 0.12 ENST00000302053.3
ENST00000403106.3
FGA
fibrinogen alpha chain
chr2_+_177134134 0.12 ENST00000249442.6
ENST00000392529.2
ENST00000443241.1
MTX2
metaxin 2
chr10_-_79397479 0.12 ENST00000404771.3
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr2_-_71222466 0.11 ENST00000606025.1
AC007040.11
Uncharacterized protein
chr9_-_14910990 0.11 ENST00000380881.4
ENST00000422223.2
FREM1
FRAS1 related extracellular matrix 1
chr2_-_88427568 0.11 ENST00000393750.3
ENST00000295834.3
FABP1
fatty acid binding protein 1, liver
chr6_-_26043885 0.11 ENST00000357905.2
HIST1H2BB
histone cluster 1, H2bb
chr3_+_125694347 0.11 ENST00000505382.1
ENST00000511082.1
ROPN1B
rhophilin associated tail protein 1B
chr11_+_33902189 0.11 ENST00000330381.2
AC132216.1
HCG1785179; PRO1787; Uncharacterized protein
chr5_+_140201183 0.11 ENST00000529619.1
ENST00000529859.1
ENST00000378126.3
PCDHA5
protocadherin alpha 5
chr12_+_119616447 0.10 ENST00000281938.2
HSPB8
heat shock 22kDa protein 8
chr5_+_40909354 0.10 ENST00000313164.9
C7
complement component 7
chr12_-_122018346 0.10 ENST00000377069.4
KDM2B
lysine (K)-specific demethylase 2B
chr1_-_157014865 0.09 ENST00000361409.2
ARHGEF11
Rho guanine nucleotide exchange factor (GEF) 11
chr21_-_43735628 0.09 ENST00000291525.10
ENST00000518498.1
TFF3
trefoil factor 3 (intestinal)
chr2_+_90192768 0.09 ENST00000390275.2
IGKV1D-13
immunoglobulin kappa variable 1D-13
chr12_+_40787194 0.09 ENST00000425730.2
ENST00000454784.4
MUC19
mucin 19, oligomeric
chr11_-_102496063 0.09 ENST00000260228.2
MMP20
matrix metallopeptidase 20
chrY_-_16098393 0.08 ENST00000250825.4
VCY
variable charge, Y-linked
chr16_-_87350970 0.08 ENST00000567970.1
C16orf95
chromosome 16 open reading frame 95
chr12_+_19282643 0.08 ENST00000317589.4
ENST00000355397.3
ENST00000359180.3
ENST00000309364.4
ENST00000540972.1
ENST00000429027.2
PLEKHA5
pleckstrin homology domain containing, family A member 5
chr12_-_28123206 0.08 ENST00000542963.1
ENST00000535992.1
PTHLH
parathyroid hormone-like hormone
chr12_-_71512027 0.08 ENST00000549357.1
CTD-2021H9.3
Uncharacterized protein
chrY_+_16168097 0.07 ENST00000250823.4
VCY1B
variable charge, Y-linked 1B
chr11_+_74699942 0.07 ENST00000526068.1
ENST00000532963.1
ENST00000531619.1
ENST00000534628.1
ENST00000545272.1
NEU3
sialidase 3 (membrane sialidase)
chr21_-_19775973 0.07 ENST00000284885.3
TMPRSS15
transmembrane protease, serine 15
chr8_+_1993152 0.07 ENST00000262113.4
MYOM2
myomesin 2
chr12_-_28122980 0.07 ENST00000395868.3
ENST00000534890.1
PTHLH
parathyroid hormone-like hormone
chr1_-_10003372 0.07 ENST00000377223.1
ENST00000541052.1
ENST00000377213.1
LZIC
leucine zipper and CTNNBIP1 domain containing
chr1_-_161193349 0.07 ENST00000469730.2
ENST00000463273.1
ENST00000464492.1
ENST00000367990.3
ENST00000470459.2
ENST00000468465.1
ENST00000463812.1
APOA2
apolipoprotein A-II
chr16_-_52119019 0.07 ENST00000561513.1
ENST00000565742.1
LINC00919
long intergenic non-protein coding RNA 919
chr2_+_177134201 0.07 ENST00000452865.1
MTX2
metaxin 2
chr8_+_1993173 0.06 ENST00000523438.1
MYOM2
myomesin 2
chr2_-_58468437 0.06 ENST00000403676.1
ENST00000427708.2
ENST00000403295.3
ENST00000446381.1
ENST00000417361.1
ENST00000233741.4
ENST00000402135.3
ENST00000540646.1
ENST00000449070.1
FANCL
Fanconi anemia, complementation group L
chrX_-_53350522 0.06 ENST00000396435.3
ENST00000375368.5
IQSEC2
IQ motif and Sec7 domain 2
chr9_-_99382065 0.06 ENST00000265659.2
ENST00000375241.1
ENST00000375236.1
CDC14B
cell division cycle 14B
chr8_-_124553437 0.06 ENST00000517956.1
ENST00000443022.2
FBXO32
F-box protein 32
chr2_-_62081148 0.06 ENST00000404929.1
FAM161A
family with sequence similarity 161, member A
chr16_+_28648975 0.06 ENST00000529716.1
NPIPB8
nuclear pore complex interacting protein family, member B8
chrX_-_55020511 0.06 ENST00000375006.3
ENST00000374992.2
PFKFB1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr7_-_123198284 0.05 ENST00000355749.2
NDUFA5
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr8_+_67104323 0.05 ENST00000518412.1
ENST00000518035.1
ENST00000517725.1
LINC00967
long intergenic non-protein coding RNA 967
chr16_-_21868978 0.05 ENST00000357370.5
ENST00000451409.1
ENST00000341400.7
ENST00000518761.4
NPIPB4
nuclear pore complex interacting protein family, member B4
chr8_+_32579341 0.05 ENST00000519240.1
ENST00000539990.1
NRG1
neuregulin 1
chr6_+_37012607 0.05 ENST00000423336.1
COX6A1P2
cytochrome c oxidase subunit VIa polypeptide 1 pseudogene 2
chr6_-_26189304 0.05 ENST00000340756.2
HIST1H4D
histone cluster 1, H4d
chr4_-_70826725 0.05 ENST00000353151.3
CSN2
casein beta
chr4_+_74347400 0.05 ENST00000226355.3
AFM
afamin
chr16_-_20364030 0.04 ENST00000396134.2
ENST00000573567.1
ENST00000570757.1
ENST00000424589.1
ENST00000302509.4
ENST00000571174.1
ENST00000576688.1
UMOD
uromodulin
chr15_-_51397473 0.04 ENST00000327536.5
TNFAIP8L3
tumor necrosis factor, alpha-induced protein 8-like 3
chr16_-_21868739 0.04 ENST00000415645.2
NPIPB4
nuclear pore complex interacting protein family, member B4
chr11_+_74699703 0.03 ENST00000529024.1
ENST00000544263.1
NEU3
sialidase 3 (membrane sialidase)
chr12_-_11091862 0.03 ENST00000537503.1
TAS2R14
taste receptor, type 2, member 14
chr18_+_74240610 0.03 ENST00000578092.1
ENST00000578613.1
ENST00000583578.1
LINC00908
long intergenic non-protein coding RNA 908
chr16_+_22524844 0.03 ENST00000538606.1
ENST00000424340.1
ENST00000517539.1
ENST00000528249.1
NPIPB5
nuclear pore complex interacting protein family, member B5
chr17_-_42327236 0.03 ENST00000399246.2
AC003102.1
AC003102.1
chr16_-_20364122 0.03 ENST00000396138.4
ENST00000577168.1
UMOD
uromodulin
chr1_+_63063152 0.03 ENST00000371129.3
ANGPTL3
angiopoietin-like 3
chr19_+_46000479 0.03 ENST00000456399.2
PPM1N
protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)
chr14_+_22948510 0.03 ENST00000390483.1
TRAJ56
T cell receptor alpha joining 56
chrY_+_23698778 0.03 ENST00000303902.5
RBMY1A1
RNA binding motif protein, Y-linked, family 1, member A1
chr19_+_55235969 0.03 ENST00000402254.2
ENST00000538269.1
ENST00000541392.1
ENST00000291860.1
ENST00000396284.2
KIR3DL1
KIR3DL3
KIR2DL4
killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3
killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
chr18_-_69246186 0.03 ENST00000568095.1
RP11-510D19.1
RP11-510D19.1
chr8_+_26247878 0.02 ENST00000518611.1
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chrX_+_128674213 0.02 ENST00000371113.4
ENST00000357121.5
OCRL
oculocerebrorenal syndrome of Lowe
chr1_+_234509186 0.02 ENST00000366615.4
COA6
cytochrome c oxidase assembly factor 6 homolog (S. cerevisiae)
chr4_-_139051839 0.02 ENST00000514600.1
ENST00000513895.1
ENST00000512536.1
LINC00616
long intergenic non-protein coding RNA 616
chr16_-_21436459 0.02 ENST00000448012.2
ENST00000504841.2
ENST00000419180.2
NPIPB3
nuclear pore complex interacting protein family, member B3
chr13_+_73629107 0.02 ENST00000539231.1
KLF5
Kruppel-like factor 5 (intestinal)
chr3_-_107596910 0.02 ENST00000464359.2
ENST00000464823.1
ENST00000466155.1
ENST00000473528.2
ENST00000608306.1
ENST00000488852.1
ENST00000608137.1
ENST00000608307.1
ENST00000609429.1
ENST00000601385.1
ENST00000475362.1
ENST00000600240.1
ENST00000600749.1
LINC00635
long intergenic non-protein coding RNA 635
chr11_+_59807748 0.02 ENST00000278855.2
ENST00000532905.1
PLAC1L
oocyte secreted protein 2
chr9_-_23821842 0.02 ENST00000544538.1
ELAVL2
ELAV like neuron-specific RNA binding protein 2
chr16_+_19467772 0.02 ENST00000219821.5
ENST00000561503.1
ENST00000564959.1
TMC5
transmembrane channel-like 5
chr19_-_16008880 0.02 ENST00000011989.7
ENST00000221700.6
CYP4F2
cytochrome P450, family 4, subfamily F, polypeptide 2
chrY_-_24038660 0.01 ENST00000382677.3
RBMY1D
RNA binding motif protein, Y-linked, family 1, member D
chr1_+_112016414 0.01 ENST00000343534.5
ENST00000369718.3
C1orf162
chromosome 1 open reading frame 162
chr18_+_55018044 0.01 ENST00000324000.3
ST8SIA3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr1_+_160709055 0.01 ENST00000368043.3
ENST00000368042.3
ENST00000458602.2
ENST00000458104.2
SLAMF7
SLAM family member 7
chr2_+_85822857 0.01 ENST00000306368.4
ENST00000414390.1
ENST00000456023.1
RNF181
ring finger protein 181
chr14_-_46185155 0.01 ENST00000555442.1
RP11-369C8.1
RP11-369C8.1
chr1_+_145413268 0.01 ENST00000421822.2
ENST00000336751.5
ENST00000497365.1
ENST00000475797.1
HFE2
hemochromatosis type 2 (juvenile)
chrX_-_118699325 0.01 ENST00000320339.4
ENST00000371594.4
ENST00000536133.1
CXorf56
chromosome X open reading frame 56
chr6_+_52051171 0.01 ENST00000340057.1
IL17A
interleukin 17A
chr17_-_5342380 0.01 ENST00000225698.4
C1QBP
complement component 1, q subcomponent binding protein
chr3_-_111314230 0.00 ENST00000317012.4
ZBED2
zinc finger, BED-type containing 2
chr9_-_7800067 0.00 ENST00000358227.4
TMEM261
transmembrane protein 261
chr7_-_44530479 0.00 ENST00000355451.7
NUDCD3
NudC domain containing 3

Network of associatons between targets according to the STRING database.

First level regulatory network of SIX6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0015722 canalicular bile acid transport(GO:0015722)
0.1 3.5 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 0.5 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.1 0.3 GO:0046495 nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
0.1 0.4 GO:0061760 antifungal innate immune response(GO:0061760)
0.1 0.3 GO:0021592 midbrain-hindbrain boundary morphogenesis(GO:0021555) fourth ventricle development(GO:0021592)
0.1 0.4 GO:0000430 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.1 0.7 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.1 0.3 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.0 0.1 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.2 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.2 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.3 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.1 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.1 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.0 0.1 GO:0010903 regulation of very-low-density lipoprotein particle remodeling(GO:0010901) negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903) negative regulation of cholesterol import(GO:0060621) negative regulation of sterol import(GO:2000910)
0.0 0.1 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.2 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.0 GO:1903487 regulation of lactation(GO:1903487)
0.0 0.1 GO:0072023 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.0 0.2 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.5 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.0 0.3 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.1 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.1 GO:0034465 response to carbon monoxide(GO:0034465)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.3 GO:1990393 3M complex(GO:1990393)
0.0 0.4 GO:0016589 NURF complex(GO:0016589)
0.0 0.3 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.1 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.2 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.1 0.3 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.5 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.2 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.2 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.1 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.3 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.5 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.7 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.1 GO:0052794 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.1 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.1 GO:0043208 interleukin-2 receptor binding(GO:0005134) glycosphingolipid binding(GO:0043208)
0.0 0.2 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.1 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.0 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.5 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.3 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.5 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends