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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for SMAD4

Z-value: 1.00

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Transcription factors associated with SMAD4

Gene Symbol Gene ID Gene Info
ENSG00000141646.9 SMAD family member 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SMAD4hg19_v2_chr18_+_48494361_48494426-0.272.0e-01Click!

Activity profile of SMAD4 motif

Sorted Z-values of SMAD4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_100111580 1.74 ENST00000605497.1
palmdelphin
chr17_+_61562201 1.71 ENST00000290863.6
ENST00000413513.3
ENST00000421982.2
angiotensin I converting enzyme
chr1_+_100111479 1.60 ENST00000263174.4
palmdelphin
chr17_+_61562178 1.51 ENST00000490216.2
angiotensin I converting enzyme
chr5_-_111092930 1.31 ENST00000257435.7
neuronal regeneration related protein
chr12_-_9913489 1.24 ENST00000228434.3
ENST00000536709.1
CD69 molecule
chr3_-_112127981 1.18 ENST00000486726.2
RP11-231E6.1
chr4_+_55524085 1.18 ENST00000412167.2
ENST00000288135.5
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
chr4_+_74606223 1.17 ENST00000307407.3
ENST00000401931.1
interleukin 8
chr1_+_110453109 1.16 ENST00000525659.1
colony stimulating factor 1 (macrophage)
chr1_+_155100342 1.15 ENST00000368406.2
ephrin-A1
chr2_+_173686303 1.14 ENST00000397087.3
Rap guanine nucleotide exchange factor (GEF) 4
chr1_+_212782012 1.14 ENST00000341491.4
ENST00000366985.1
activating transcription factor 3
chr10_+_75670862 1.11 ENST00000446342.1
ENST00000372764.3
ENST00000372762.4
plasminogen activator, urokinase
chr1_-_151345159 1.11 ENST00000458566.1
ENST00000447402.3
ENST00000426705.2
ENST00000435071.1
ENST00000368868.5
selenium binding protein 1
chr2_+_16080659 1.08 ENST00000281043.3
v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
chr11_+_43964055 1.06 ENST00000528572.1
chromosome 11 open reading frame 96
chr8_-_48651648 1.05 ENST00000408965.3
CCAAT/enhancer binding protein (C/EBP), delta
chr20_+_30598231 1.05 ENST00000300415.8
ENST00000262659.8
cerebral cavernous malformation 2-like
chr5_-_111093340 1.03 ENST00000508870.1
neuronal regeneration related protein
chr1_+_61869748 1.01 ENST00000357977.5
nuclear factor I/A
chr5_-_111093406 1.01 ENST00000379671.3
neuronal regeneration related protein
chr7_+_94023873 0.99 ENST00000297268.6
collagen, type I, alpha 2
chr17_+_32597232 0.99 ENST00000378569.2
ENST00000200307.4
ENST00000394627.1
ENST00000394630.3
chemokine (C-C motif) ligand 7
chr17_+_61571746 0.98 ENST00000579409.1
angiotensin I converting enzyme
chr14_+_64680854 0.91 ENST00000458046.2
spectrin repeat containing, nuclear envelope 2
chr19_+_41949054 0.88 ENST00000378187.2
chromosome 19 open reading frame 69
chr22_-_37880543 0.86 ENST00000442496.1
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr22_-_24641027 0.85 ENST00000398292.3
ENST00000263112.7
ENST00000418439.2
ENST00000424217.1
ENST00000327365.4
gamma-glutamyltransferase 5
chr5_-_111093081 0.83 ENST00000453526.2
ENST00000509427.1
neuronal regeneration related protein
chr1_+_155099927 0.82 ENST00000368407.3
ephrin-A1
chr1_-_32827682 0.81 ENST00000432622.1
family with sequence similarity 229, member A
chr15_+_67420441 0.79 ENST00000558894.1
SMAD family member 3
chr9_+_72002837 0.79 ENST00000377216.3
family with sequence similarity 189, member A2
chr9_-_123476612 0.78 ENST00000426959.1
multiple EGF-like-domains 9
chr1_+_101185290 0.78 ENST00000370119.4
ENST00000347652.2
ENST00000294728.2
ENST00000370115.1
vascular cell adhesion molecule 1
chr3_+_152017924 0.76 ENST00000465907.2
ENST00000492948.1
ENST00000485509.1
ENST00000464596.1
muscleblind-like splicing regulator 1
chr17_+_39382900 0.74 ENST00000377721.3
ENST00000455970.2
keratin associated protein 9-2
chr1_+_203595903 0.73 ENST00000367218.3
ENST00000367219.3
ENST00000391954.2
ATPase, Ca++ transporting, plasma membrane 4
chr15_-_82338460 0.73 ENST00000558133.1
ENST00000329713.4
mex-3 RNA binding family member B
chr4_-_186697044 0.72 ENST00000437304.2
sorbin and SH3 domain containing 2
chr11_-_33913708 0.72 ENST00000257818.2
LIM domain only 2 (rhombotin-like 1)
chr1_+_203595689 0.72 ENST00000357681.5
ATPase, Ca++ transporting, plasma membrane 4
chr7_+_48128194 0.70 ENST00000416681.1
ENST00000331803.4
ENST00000432131.1
uridine phosphorylase 1
chr14_-_92413353 0.70 ENST00000556154.1
fibulin 5
chr3_+_53195136 0.70 ENST00000394729.2
ENST00000330452.3
protein kinase C, delta
chr7_+_48128316 0.70 ENST00000341253.4
uridine phosphorylase 1
chr19_-_38916802 0.70 ENST00000587738.1
RAS guanyl releasing protein 4
chr9_-_69202204 0.69 ENST00000377473.1
forkhead box D4-like 6
chr1_+_61548225 0.68 ENST00000371187.3
nuclear factor I/A
chr17_-_42276574 0.68 ENST00000589805.1
ataxin 7-like 3
chr16_-_30032610 0.68 ENST00000574405.1
double C2-like domains, alpha
chr8_-_17579726 0.67 ENST00000381861.3
microtubule associated tumor suppressor 1
chr1_+_153746683 0.67 ENST00000271857.2
solute carrier family 27 (fatty acid transporter), member 3
chr11_+_34643600 0.67 ENST00000530286.1
ENST00000533754.1
ets homologous factor
chr9_-_140196703 0.66 ENST00000356628.2
NOTCH-regulated ankyrin repeat protein
chr2_-_27558270 0.65 ENST00000454704.1
general transcription factor IIIC, polypeptide 2, beta 110kDa
chr17_-_67138015 0.63 ENST00000284425.2
ENST00000590645.1
ATP-binding cassette, sub-family A (ABC1), member 6
chr11_+_64879317 0.63 ENST00000526809.1
ENST00000279263.7
ENST00000524986.1
ENST00000534371.1
ENST00000540748.1
ENST00000525385.1
ENST00000345348.5
ENST00000531321.1
ENST00000529414.1
ENST00000526085.1
ENST00000530750.1
transmembrane 7 superfamily member 2
chr1_+_110453608 0.62 ENST00000369801.1
colony stimulating factor 1 (macrophage)
chr1_+_110453462 0.62 ENST00000488198.1
colony stimulating factor 1 (macrophage)
chr1_+_228337553 0.61 ENST00000366714.2
gap junction protein, gamma 2, 47kDa
chr7_+_44663908 0.61 ENST00000543843.1
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr10_+_35456444 0.60 ENST00000361599.4
cAMP responsive element modulator
chr2_-_31360887 0.60 ENST00000420311.2
ENST00000356174.3
ENST00000324589.5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr6_+_30850697 0.59 ENST00000509639.1
ENST00000412274.2
ENST00000507901.1
ENST00000507046.1
ENST00000437124.2
ENST00000454612.2
ENST00000396342.2
discoidin domain receptor tyrosine kinase 1
chr9_-_130617029 0.59 ENST00000373203.4
endoglin
chr11_-_118134997 0.58 ENST00000278937.2
myelin protein zero-like 2
chr4_+_144258021 0.58 ENST00000262994.4
GRB2-associated binding protein 1
chr9_-_130616915 0.58 ENST00000344849.3
endoglin
chr8_+_22424551 0.57 ENST00000523348.1
sorbin and SH3 domain containing 3
chr14_-_23288930 0.57 ENST00000554517.1
ENST00000285850.7
ENST00000397529.2
ENST00000555702.1
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr9_-_75567962 0.57 ENST00000297785.3
ENST00000376939.1
aldehyde dehydrogenase 1 family, member A1
chr9_-_70178815 0.56 ENST00000377420.1
forkhead box D4-like 5
chr8_-_145028013 0.56 ENST00000354958.2
plectin
chr7_-_150754935 0.56 ENST00000297518.4
cyclin-dependent kinase 5
chr9_+_42717234 0.55 ENST00000377590.1
forkhead box D4-like 2
chr14_+_65007177 0.55 ENST00000247207.6
heat shock 70kDa protein 2
chr9_+_70917276 0.55 ENST00000342833.2
forkhead box D4-like 3
chr20_+_34680620 0.55 ENST00000430276.1
ENST00000373950.2
ENST00000452261.1
erythrocyte membrane protein band 4.1-like 1
chr9_-_123476719 0.55 ENST00000373930.3
multiple EGF-like-domains 9
chr6_+_146920116 0.55 ENST00000367493.3
androglobin
chr19_-_41859814 0.55 ENST00000221930.5
transforming growth factor, beta 1
chr5_-_141249154 0.54 ENST00000357517.5
ENST00000536585.1
protocadherin 1
chr8_-_17533838 0.54 ENST00000400046.1
microtubule associated tumor suppressor 1
chr2_+_33359646 0.54 ENST00000390003.4
ENST00000418533.2
latent transforming growth factor beta binding protein 1
chr2_+_33359687 0.53 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
latent transforming growth factor beta binding protein 1
chrX_+_54947229 0.52 ENST00000442098.1
ENST00000430420.1
ENST00000453081.1
ENST00000173898.7
ENST00000319167.8
ENST00000375022.4
ENST00000399736.1
ENST00000440072.1
ENST00000420798.2
ENST00000431115.1
ENST00000440759.1
ENST00000375041.2
trophinin
chr7_-_120497178 0.52 ENST00000441017.1
ENST00000424710.1
ENST00000433758.1
tetraspanin 12
chr16_-_77468945 0.52 ENST00000282849.5
ADAM metallopeptidase with thrombospondin type 1 motif, 18
chr14_+_102276192 0.52 ENST00000557714.1
protein phosphatase 2, regulatory subunit B', gamma
chr4_+_144257915 0.51 ENST00000262995.4
GRB2-associated binding protein 1
chr4_+_103422471 0.51 ENST00000226574.4
ENST00000394820.4
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr16_-_66952779 0.50 ENST00000570262.1
ENST00000394055.3
ENST00000299752.4
cadherin 16, KSP-cadherin
chr11_+_33563821 0.50 ENST00000321505.4
ENST00000265654.5
ENST00000389726.3
KIAA1549-like
chr19_+_13051206 0.50 ENST00000586760.1
calreticulin
chr2_-_209118974 0.49 ENST00000415913.1
ENST00000415282.1
ENST00000446179.1
isocitrate dehydrogenase 1 (NADP+), soluble
chr15_-_101835110 0.49 ENST00000560496.1
small nuclear ribonucleoprotein polypeptide A'
chr9_+_82187487 0.49 ENST00000435650.1
ENST00000414465.1
ENST00000376537.4
ENST00000376534.4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr6_+_116937636 0.48 ENST00000368581.4
ENST00000229554.5
ENST00000368580.4
radial spoke head 4 homolog A (Chlamydomonas)
chr4_-_102268484 0.48 ENST00000394853.4
protein phosphatase 3, catalytic subunit, alpha isozyme
chr1_-_46598371 0.48 ENST00000372006.1
ENST00000425892.1
ENST00000420542.1
ENST00000354242.4
ENST00000340332.6
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr9_+_82187630 0.48 ENST00000265284.6
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr3_+_159706537 0.48 ENST00000305579.2
ENST00000480787.1
ENST00000466512.1
interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
chr9_+_82188077 0.47 ENST00000425506.1
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr19_+_45251804 0.47 ENST00000164227.5
B-cell CLL/lymphoma 3
chr19_+_10765699 0.47 ENST00000590009.1
interleukin enhancer binding factor 3, 90kDa
chr3_+_184037466 0.47 ENST00000441154.1
eukaryotic translation initiation factor 4 gamma, 1
chr1_+_32827759 0.47 ENST00000373534.3
testis-specific serine kinase 3
chr2_+_69240302 0.47 ENST00000303714.4
anthrax toxin receptor 1
chr1_-_46598284 0.47 ENST00000423209.1
ENST00000262741.5
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr8_+_123793633 0.46 ENST00000314393.4
zinc fingers and homeoboxes 2
chr1_-_153599732 0.46 ENST00000392623.1
S100 calcium binding protein A13
chr16_-_10652993 0.46 ENST00000536829.1
epithelial membrane protein 2
chr4_+_38665810 0.46 ENST00000261438.5
ENST00000514033.1
Kruppel-like factor 3 (basic)
chr7_+_128312346 0.45 ENST00000480462.1
ENST00000378704.3
ENST00000477515.1
family with sequence similarity 71, member F2
chr17_-_73874654 0.45 ENST00000254816.2
tripartite motif containing 47
chr4_-_147043058 0.45 ENST00000512063.1
ENST00000507726.1
long intergenic non-protein coding RNA 1095
chr2_-_238499303 0.45 ENST00000409576.1
RAB17, member RAS oncogene family
chrX_+_135279179 0.44 ENST00000370676.3
four and a half LIM domains 1
chr14_+_61654271 0.44 ENST00000555185.1
ENST00000557294.1
ENST00000556778.1
protein kinase C, eta
chr12_-_15104040 0.43 ENST00000541644.1
ENST00000545895.1
Rho GDP dissociation inhibitor (GDI) beta
chr12_+_53443963 0.43 ENST00000546602.1
ENST00000552570.1
ENST00000549700.1
tensin like C1 domain containing phosphatase (tensin 2)
chr6_-_167571817 0.43 ENST00000366834.1
G protein-coupled receptor 31
chr8_+_29953163 0.42 ENST00000518192.1
leptin receptor overlapping transcript-like 1
chr15_-_70994612 0.42 ENST00000558758.1
ENST00000379983.2
ENST00000560441.1
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr17_-_39728303 0.42 ENST00000588431.1
ENST00000246662.4
keratin 9
chr18_+_20513782 0.42 ENST00000399722.2
ENST00000399725.2
ENST00000399721.2
ENST00000583594.1
retinoblastoma binding protein 8
chr1_+_110453203 0.42 ENST00000357302.4
ENST00000344188.5
ENST00000329608.6
colony stimulating factor 1 (macrophage)
chr4_-_102267953 0.41 ENST00000523694.2
ENST00000507176.1
protein phosphatase 3, catalytic subunit, alpha isozyme
chrX_-_48815633 0.41 ENST00000428668.2
OTU domain containing 5
chr6_+_126112074 0.40 ENST00000453302.1
ENST00000417494.1
ENST00000229634.9
nuclear receptor coactivator 7
chr19_-_49864746 0.40 ENST00000598810.1
TEA domain family member 2
chr19_-_11688447 0.40 ENST00000590420.1
acid phosphatase 5, tartrate resistant
chr8_-_29940628 0.39 ENST00000545648.1
ENST00000256255.6
transmembrane protein 66
chr19_-_38916839 0.39 ENST00000433821.2
ENST00000426920.2
ENST00000587753.1
ENST00000454404.2
ENST00000293062.9
RAS guanyl releasing protein 4
chr20_+_31619454 0.39 ENST00000349552.1
BPI fold containing family B, member 6
chr9_+_2157655 0.39 ENST00000452193.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr5_+_177540444 0.39 ENST00000274605.5
NEDD4 binding protein 3
chr15_-_70388599 0.38 ENST00000560996.1
ENST00000558201.1
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr1_-_169599353 0.38 ENST00000367793.2
ENST00000367794.2
ENST00000367792.2
ENST00000367791.2
ENST00000367788.2
selectin P (granule membrane protein 140kDa, antigen CD62)
chr16_-_66952742 0.38 ENST00000565235.2
ENST00000568632.1
ENST00000565796.1
cadherin 16, KSP-cadherin
chr11_+_59522900 0.38 ENST00000529177.1
syntaxin 3
chr19_-_58864848 0.38 ENST00000263100.3
alpha-1-B glycoprotein
chr12_-_6740802 0.38 ENST00000431922.1
lysophosphatidic acid receptor 5
chrX_+_54835493 0.38 ENST00000396224.1
melanoma antigen family D, 2
chr2_+_201997676 0.38 ENST00000462763.1
ENST00000479953.2
CASP8 and FADD-like apoptosis regulator
chr15_-_70388943 0.38 ENST00000559048.1
ENST00000560939.1
ENST00000440567.3
ENST00000557907.1
ENST00000558379.1
ENST00000451782.2
ENST00000559929.1
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr1_-_160231451 0.38 ENST00000495887.1
DDB1 and CUL4 associated factor 8
chr19_-_38916822 0.38 ENST00000586305.1
RAS guanyl releasing protein 4
chr19_-_4559814 0.38 ENST00000586582.1
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr7_+_86273952 0.38 ENST00000536043.1
glutamate receptor, metabotropic 3
chr1_+_89829610 0.37 ENST00000370456.4
ENST00000535065.1
guanylate binding protein family, member 6
chr9_-_14180778 0.37 ENST00000380924.1
ENST00000543693.1
nuclear factor I/B
chr6_-_35656712 0.37 ENST00000357266.4
ENST00000542713.1
FK506 binding protein 5
chr19_+_49404041 0.37 ENST00000263273.5
ENST00000424608.1
nucleobindin 1
chr6_-_30710265 0.37 ENST00000438162.1
ENST00000454845.1
flotillin 1
chr2_-_239140011 0.37 ENST00000409376.1
ENST00000409070.1
ENST00000409942.1
Protein LOC151174
chr2_-_228028829 0.37 ENST00000396625.3
ENST00000329662.7
collagen, type IV, alpha 4
chr6_-_30709980 0.37 ENST00000416018.1
ENST00000445853.1
ENST00000413165.1
ENST00000418160.1
flotillin 1
chr6_-_35656685 0.36 ENST00000539068.1
ENST00000540787.1
FK506 binding protein 5
chr17_-_61777459 0.36 ENST00000578993.1
ENST00000583211.1
ENST00000259006.3
LIM domain containing 2
chr17_-_18585131 0.36 ENST00000443457.1
ENST00000583002.1
zinc finger protein 286B
chr16_-_20911641 0.36 ENST00000564349.1
ENST00000324344.4
ERI1 exoribonuclease family member 2
DCN1, defective in cullin neddylation 1, domain containing 3
chr3_+_38017264 0.36 ENST00000436654.1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr11_-_44972418 0.36 ENST00000525680.1
ENST00000528290.1
ENST00000530035.1
tumor protein p53 inducible protein 11
chr7_-_62858860 0.36 ENST00000593633.1
AC073188.1
chr2_-_74667612 0.36 ENST00000305557.5
ENST00000233330.6
rhotekin
chr2_+_201997595 0.36 ENST00000470178.2
CASP8 and FADD-like apoptosis regulator
chr18_+_8717369 0.35 ENST00000359865.3
ENST00000400050.3
ENST00000306285.7
SOGA family member 2
chr7_+_86273218 0.35 ENST00000361669.2
glutamate receptor, metabotropic 3
chr19_+_38755042 0.35 ENST00000301244.7
serine peptidase inhibitor, Kunitz type, 2
chr22_+_23213658 0.35 ENST00000390318.2
immunoglobulin lambda variable 4-3
chr9_-_21202204 0.35 ENST00000239347.3
interferon, alpha 7
chr14_-_24806588 0.35 ENST00000555591.1
ENST00000554569.1
Uncharacterized protein
receptor-interacting serine-threonine kinase 3
chr1_-_169599314 0.35 ENST00000367786.2
ENST00000458599.2
ENST00000367795.2
ENST00000263686.6
selectin P (granule membrane protein 140kDa, antigen CD62)
chr11_-_101000445 0.34 ENST00000534013.1
progesterone receptor
chr11_-_67120974 0.34 ENST00000539074.1
ENST00000312419.3
polymerase (DNA-directed), delta 4, accessory subunit
chr12_-_15103621 0.34 ENST00000536592.1
Rho GDP dissociation inhibitor (GDI) beta
chr15_+_89402148 0.34 ENST00000560601.1
aggrecan
chr1_-_207095324 0.34 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
Fas apoptotic inhibitory molecule 3
chr1_+_61548374 0.33 ENST00000485903.2
ENST00000371185.2
ENST00000371184.2
nuclear factor I/A
chr3_+_38347427 0.33 ENST00000273173.4
solute carrier family 22, member 14
chr6_-_169654139 0.33 ENST00000366787.3
thrombospondin 2
chr7_+_114562172 0.33 ENST00000393486.1
ENST00000257724.3
MyoD family inhibitor domain containing
chr8_+_29952914 0.33 ENST00000321250.8
ENST00000518001.1
ENST00000520682.1
ENST00000442880.2
ENST00000523116.1
leptin receptor overlapping transcript-like 1
chr20_-_57582296 0.33 ENST00000217131.5
cathepsin Z
chr16_+_2880296 0.33 ENST00000571723.1
zymogen granule protein 16B
chr22_+_22385332 0.33 ENST00000390282.2
immunoglobulin lambda variable 4-69
chr17_+_7792101 0.33 ENST00000358181.4
ENST00000330494.7
chromodomain helicase DNA binding protein 3
chr19_-_51456321 0.32 ENST00000391809.2
kallikrein-related peptidase 5
chr19_+_38755203 0.32 ENST00000587090.1
ENST00000454580.3
serine peptidase inhibitor, Kunitz type, 2
chr22_+_50528308 0.32 ENST00000545383.1
ENST00000262794.5
Mov10l1, Moloney leukemia virus 10-like 1, homolog (mouse)
chr19_+_54371114 0.32 ENST00000448420.1
ENST00000439000.1
ENST00000391770.4
ENST00000391771.1
myeloid-associated differentiation marker
chr17_-_40288449 0.32 ENST00000552162.1
ENST00000550504.1
RAB5C, member RAS oncogene family
chr4_+_126237554 0.32 ENST00000394329.3
FAT atypical cadherin 4
chr2_-_239140276 0.32 ENST00000334973.4
Protein LOC151174
chr3_+_141103634 0.31 ENST00000507722.1
zinc finger and BTB domain containing 38
chr2_-_112237835 0.31 ENST00000442293.1
ENST00000439494.1
MIR4435-1 host gene (non-protein coding)
chr9_+_34990219 0.31 ENST00000541010.1
ENST00000454002.2
ENST00000545841.1
DnaJ (Hsp40) homolog, subfamily B, member 5

Network of associatons between targets according to the STRING database.

First level regulatory network of SMAD4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.2 GO:1903597 negative regulation of gap junction assembly(GO:1903597)
0.6 2.9 GO:1902228 mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
0.6 1.1 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.5 1.5 GO:2000283 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.4 1.2 GO:0038109 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) erythropoietin-mediated signaling pathway(GO:0038162)
0.4 1.2 GO:0001300 chronological cell aging(GO:0001300)
0.4 1.1 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.4 1.4 GO:0006218 uridine catabolic process(GO:0006218)
0.3 1.0 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.3 1.8 GO:0014028 notochord formation(GO:0014028)
0.3 0.9 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.3 0.8 GO:0006097 glyoxylate cycle(GO:0006097)
0.2 0.6 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.2 1.3 GO:0044415 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.2 0.6 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.2 0.7 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
0.2 0.2 GO:2000547 regulation of dendritic cell dendrite assembly(GO:2000547)
0.2 0.2 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
0.2 0.5 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.2 0.9 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 0.4 GO:0019364 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.1 1.0 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1 0.6 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1 0.7 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 0.6 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.1 0.6 GO:0090182 regulation of secretion of lysosomal enzymes(GO:0090182)
0.1 0.3 GO:2000452 CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:0035698) positive regulation of necroptotic process(GO:0060545) regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:2000452)
0.1 0.7 GO:0002760 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.1 0.6 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.1 0.8 GO:0022614 membrane to membrane docking(GO:0022614)
0.1 0.8 GO:0071461 cellular response to redox state(GO:0071461)
0.1 0.3 GO:1903413 cellular response to bile acid(GO:1903413) response to iron ion starvation(GO:1990641)
0.1 1.0 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 0.5 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956)
0.1 1.0 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 0.6 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.5 GO:0044858 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.1 0.5 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.1 0.3 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.1 0.3 GO:0060931 sinoatrial node cell development(GO:0060931)
0.1 0.6 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.1 0.7 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.1 0.4 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.1 1.0 GO:2000510 positive regulation of dendritic cell chemotaxis(GO:2000510)
0.1 0.3 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.1 1.2 GO:0044857 plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857)
0.1 0.7 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.1 0.3 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.1 1.2 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.1 0.1 GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.1 0.3 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.1 0.6 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 1.0 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 1.9 GO:0072189 ureter development(GO:0072189)
0.1 1.1 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1 0.9 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.7 GO:0072718 response to cisplatin(GO:0072718)
0.1 0.2 GO:0098759 response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.1 0.2 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1 0.3 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.1 0.6 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.4 GO:0034351 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.1 0.2 GO:0072579 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.1 1.0 GO:0043589 skin morphogenesis(GO:0043589)
0.1 0.6 GO:0015889 cobalamin transport(GO:0015889)
0.1 0.4 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.1 0.2 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 0.2 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.1 0.3 GO:0048749 compound eye development(GO:0048749)
0.1 0.6 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.1 0.3 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.1 0.5 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 0.4 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1 0.2 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.1 0.4 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 0.3 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.1 0.6 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.1 0.7 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 0.2 GO:0003099 positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.1 0.3 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.4 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.1 0.2 GO:0052314 phytoalexin metabolic process(GO:0052314)
0.1 0.2 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.9 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.1 0.3 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.0 0.2 GO:0019075 virus maturation(GO:0019075)
0.0 0.2 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.0 0.2 GO:0048817 negative regulation of hair follicle maturation(GO:0048817)
0.0 0.2 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.0 0.1 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.0 GO:0034125 negative regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034125)
0.0 0.4 GO:0050893 sensory processing(GO:0050893)
0.0 0.2 GO:1904431 positive regulation of t-circle formation(GO:1904431)
0.0 0.3 GO:0038086 VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091)
0.0 0.1 GO:0002644 negative regulation of tolerance induction(GO:0002644)
0.0 0.2 GO:0031337 cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) positive regulation of homocysteine metabolic process(GO:0050668)
0.0 0.5 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.0 0.3 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.2 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.0 0.4 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.2 GO:0032431 positive regulation of phospholipase A2 activity(GO:0032430) activation of phospholipase A2 activity(GO:0032431)
0.0 0.3 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.0 0.2 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.2 GO:0016321 female meiosis chromosome segregation(GO:0016321)
0.0 0.1 GO:1900111 positive regulation of histone H3-K9 dimethylation(GO:1900111)
0.0 0.2 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.1 GO:0042631 cellular response to water deprivation(GO:0042631)
0.0 0.2 GO:0070458 cellular detoxification of nitrogen compound(GO:0070458)
0.0 0.8 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.1 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.0 0.1 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.0 0.3 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 0.3 GO:0002774 Fc receptor mediated inhibitory signaling pathway(GO:0002774)
0.0 0.2 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 2.1 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.3 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 0.9 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 1.1 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.2 GO:0043305 negative regulation of mast cell activation involved in immune response(GO:0033007) negative regulation of mast cell degranulation(GO:0043305)
0.0 0.2 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.3 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 1.1 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.1 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0 0.1 GO:0031133 regulation of axon diameter(GO:0031133)
0.0 0.2 GO:0015862 uridine transport(GO:0015862)
0.0 0.1 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.2 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.0 0.1 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.1 GO:0003064 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.0 0.2 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.0 0.3 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.2 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.3 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.1 GO:0035026 leading edge cell differentiation(GO:0035026)
0.0 0.2 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.6 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.6 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.1 GO:0034227 tRNA thio-modification(GO:0034227)
0.0 0.3 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:1902871 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.0 0.1 GO:0048867 ganglion mother cell fate determination(GO:0007402) stem cell fate determination(GO:0048867)
0.0 0.5 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.1 GO:0032900 negative regulation of neurotrophin production(GO:0032900)
0.0 0.3 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.0 0.5 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.1 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.1 GO:0034144 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)
0.0 0.1 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
0.0 0.7 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.0 0.3 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.1 GO:0051140 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0 0.1 GO:0042351 'de novo' GDP-L-fucose biosynthetic process(GO:0042351)
0.0 0.1 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.0 0.1 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.3 GO:0010225 response to UV-C(GO:0010225)
0.0 0.0 GO:0006447 regulation of translational initiation by iron(GO:0006447)
0.0 0.1 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.0 0.4 GO:0048368 lateral mesoderm development(GO:0048368)
0.0 0.2 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.3 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.2 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.0 0.6 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.1 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 0.1 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.0 0.1 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.0 0.1 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.0 0.7 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.3 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.4 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.0 0.1 GO:0021943 formation of radial glial scaffolds(GO:0021943)
0.0 0.4 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.4 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0021590 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.0 0.4 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.1 GO:0021633 optic nerve structural organization(GO:0021633)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.0 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.0 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.1 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 0.1 GO:0001787 natural killer cell proliferation(GO:0001787)
0.0 0.0 GO:0070101 positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.0 0.1 GO:0043129 surfactant homeostasis(GO:0043129)
0.0 0.2 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.0 0.2 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.2 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.3 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.0 0.1 GO:2000196 positive regulation of female gonad development(GO:2000196)
0.0 0.2 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.1 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.0 0.1 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.0 0.2 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.1 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0 0.1 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.1 GO:0031053 primary miRNA processing(GO:0031053)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.6 GO:0010842 retina layer formation(GO:0010842)
0.0 0.3 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.1 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.0 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.0 0.1 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.0 GO:0007412 axon target recognition(GO:0007412)
0.0 0.1 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.0 0.0 GO:1902725 regulation of skeletal muscle tissue growth(GO:0048631) negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.7 GO:0007566 embryo implantation(GO:0007566)
0.0 0.4 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.6 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.2 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 1.2 GO:0001895 retina homeostasis(GO:0001895)
0.0 0.2 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.2 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.2 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636)
0.0 0.0 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.0 0.2 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.0 0.0 GO:0071350 interleukin-15-mediated signaling pathway(GO:0035723) cellular response to interleukin-15(GO:0071350)
0.0 0.3 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.0 0.2 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0 0.2 GO:0060285 cilium-dependent cell motility(GO:0060285)
0.0 0.3 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.1 GO:0035865 cellular response to potassium ion(GO:0035865)
0.0 0.0 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 0.3 GO:0042269 regulation of natural killer cell mediated cytotoxicity(GO:0042269)
0.0 0.1 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.2 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.0 0.1 GO:0003356 regulation of cilium beat frequency(GO:0003356)
0.0 0.1 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.0 0.3 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.1 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.0 0.0 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.0 0.5 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.1 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.0 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.0 0.1 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.6 GO:0061098 positive regulation of protein tyrosine kinase activity(GO:0061098)
0.0 1.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.3 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
0.0 0.1 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 2.4 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.0 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.0 0.2 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.0 GO:2000909 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.9 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.4 1.2 GO:0072563 endothelial microparticle(GO:0072563)
0.4 1.1 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.3 0.8 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.2 0.5 GO:0001534 radial spoke(GO:0001534)
0.1 0.7 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.1 0.5 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 1.2 GO:0071953 elastic fiber(GO:0071953)
0.1 0.4 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.1 0.9 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.8 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.4 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.1 0.7 GO:0097209 epidermal lamellar body(GO:0097209)
0.1 0.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.7 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 1.0 GO:0070652 HAUS complex(GO:0070652)
0.1 0.6 GO:0036128 CatSper complex(GO:0036128)
0.1 0.3 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 0.3 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 1.0 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.5 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 1.4 GO:0097342 ripoptosome(GO:0097342)
0.1 0.8 GO:0031088 platelet dense granule membrane(GO:0031088)
0.1 0.7 GO:0016600 flotillin complex(GO:0016600)
0.1 0.6 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 0.5 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 1.8 GO:0042629 mast cell granule(GO:0042629)
0.0 0.7 GO:0030478 actin cap(GO:0030478)
0.0 0.2 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.6 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.4 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 1.5 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.3 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 1.0 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.3 GO:0070552 BRISC complex(GO:0070552)
0.0 0.9 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.7 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.1 GO:0097232 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.0 0.1 GO:0031523 Myb complex(GO:0031523)
0.0 0.1 GO:0071821 FANCM-MHF complex(GO:0071821)
0.0 0.1 GO:1990032 parallel fiber(GO:1990032)
0.0 0.2 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.5 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.2 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.4 GO:0031906 late endosome lumen(GO:0031906)
0.0 0.8 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.2 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.0 1.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.2 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.6 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.2 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.7 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.3 GO:0045179 apical cortex(GO:0045179)
0.0 0.1 GO:0020005 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005) other organism cytoplasm(GO:0097679)
0.0 1.4 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.6 GO:0098553 integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.4 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.1 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.0 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.2 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 4.0 GO:0043197 dendritic spine(GO:0043197)
0.0 0.8 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.1 GO:0035976 AP1 complex(GO:0035976)
0.0 2.2 GO:0031091 platelet alpha granule(GO:0031091)
0.0 0.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 0.5 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.2 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.1 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.3 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.2 GO:0030897 HOPS complex(GO:0030897)
0.0 0.1 GO:0071546 pi-body(GO:0071546)
0.0 0.4 GO:0005922 connexon complex(GO:0005922)
0.0 4.3 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.9 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.5 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0005869 dynactin complex(GO:0005869)
0.0 0.5 GO:0099738 cell cortex region(GO:0099738)
0.0 1.4 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.1 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.2 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.1 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.2 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.0 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.1 GO:0097433 dense body(GO:0097433)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.2 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.5 1.5 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.4 2.9 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.3 1.4 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.3 0.8 GO:0051990 isocitrate dehydrogenase (NADP+) activity(GO:0004450) (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.2 1.2 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.2 0.9 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.2 1.1 GO:0050436 microfibril binding(GO:0050436)
0.2 0.6 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.2 1.0 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.2 0.8 GO:0001069 regulatory region RNA binding(GO:0001069)
0.2 1.9 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.2 0.8 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.2 0.6 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.1 1.1 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 0.6 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.9 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.7 GO:0004882 androgen receptor activity(GO:0004882)
0.1 0.6 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1 0.8 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.1 0.3 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.1 0.3 GO:0045518 interleukin-22 receptor binding(GO:0045518)
0.1 1.1 GO:0008430 selenium binding(GO:0008430)
0.1 0.9 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.8 GO:0030620 U2 snRNA binding(GO:0030620)
0.1 1.2 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1 0.9 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 1.1 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.3 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.6 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.1 1.6 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 0.2 GO:0019959 interleukin-8 binding(GO:0019959)
0.1 0.3 GO:0032810 sterol response element binding(GO:0032810)
0.1 0.2 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.1 0.4 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.2 GO:0061598 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.1 1.0 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 1.0 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.2 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.1 0.6 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.3 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.1 0.5 GO:0019237 centromeric DNA binding(GO:0019237)
0.1 0.3 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 0.5 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.1 0.7 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 0.9 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.2 GO:0033981 D-dopachrome decarboxylase activity(GO:0033981)
0.0 0.4 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.4 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.5 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.2 GO:0047820 D-glutamate cyclase activity(GO:0047820)
0.0 0.2 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.0 0.1 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.0 0.8 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.3 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.6 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.5 GO:0045159 myosin II binding(GO:0045159)
0.0 0.6 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.3 GO:0032396 inhibitory MHC class I receptor activity(GO:0032396)
0.0 0.5 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.1 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 0.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.6 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.3 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.7 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.3 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.0 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.4 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.5 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.2 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 1.0 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.1 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.3 GO:0042731 PH domain binding(GO:0042731)
0.0 0.4 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.2 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 1.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0034584 piRNA binding(GO:0034584)
0.0 0.2 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.3 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
0.0 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.2 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.3 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.8 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.7 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.5 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.1 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.1 GO:0004507 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.0 0.4 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.2 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.1 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.0 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.2 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.1 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.1 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.0 0.4 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.6 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.6 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.4 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.2 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.3 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.3 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.2 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 1.2 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.1 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.0 0.0 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.0 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.3 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.2 GO:0051400 BH domain binding(GO:0051400)
0.0 0.0 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.0 0.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.0 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.4 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.1 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.1 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0 0.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.2 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 2.0 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.2 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.2 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.2 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.1 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.2 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.0 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.3 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.2 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.1 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.1 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.1 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.1 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 0.6 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.4 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.2 GO:0043295 glutathione binding(GO:0043295)
0.0 0.1 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 1.7 GO:0005178 integrin binding(GO:0005178)
0.0 0.1 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0 0.1 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.3 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.5 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.5 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.1 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.9 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 1.7 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 2.6 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 3.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.2 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.4 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 1.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 3.0 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 2.0 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.2 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 1.5 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 2.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.0 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.2 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.5 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.7 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.8 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 1.5 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.3 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 1.1 PID AP1 PATHWAY AP-1 transcription factor network
0.0 1.4 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.8 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.4 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.1 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.4 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.2 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.5 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.2 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 0.5 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 1.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 2.0 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.8 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.9 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.6 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 1.1 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 1.7 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.9 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.9 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 1.0 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 1.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.5 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 1.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 1.8 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0 0.7 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.3 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.6 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.0 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 1.2 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 2.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.5 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.9 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.6 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.8 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.7 REACTOME KINESINS Genes involved in Kinesins
0.0 0.4 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.6 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.6 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.3 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.8 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.5 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.4 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.8 REACTOME RNA POL III TRANSCRIPTION Genes involved in RNA Polymerase III Transcription
0.0 0.3 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.1 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.2 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.4 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.2 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.1 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.2 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.9 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions