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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for SOX1

Z-value: 0.83

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Transcription factors associated with SOX1

Gene Symbol Gene ID Gene Info
SOX1
ENSG00000182968.3 SRY-box transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX1hg19_v2_chr13_+_112721913_112721913-0.029.2e-01Click!

Activity profile of SOX1 motif

Sorted Z-values of SOX1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_154622652 3.53 ENST00000260010.6
TLR2
toll-like receptor 2
chr5_-_150460914 2.73 ENST00000389378.2
TNIP1
TNFAIP3 interacting protein 1
chr19_-_10491234 2.52 ENST00000524462.1
ENST00000531836.1
ENST00000525621.1
TYK2
tyrosine kinase 2
chr1_+_65613340 1.82 ENST00000546702.1
AK4
adenylate kinase 4
chr3_-_189840223 1.68 ENST00000427335.2
LEPREL1
leprecan-like 1
chr11_-_57177586 1.59 ENST00000529411.1
RP11-872D17.8
Uncharacterized protein
chr5_-_16916624 1.35 ENST00000513882.1
MYO10
myosin X
chr19_+_3762645 1.20 ENST00000330133.4
MRPL54
mitochondrial ribosomal protein L54
chr18_+_21719018 1.19 ENST00000585037.1
ENST00000415309.2
ENST00000399481.2
ENST00000577705.1
ENST00000327201.6
CABYR
calcium binding tyrosine-(Y)-phosphorylation regulated
chr1_+_65613217 1.14 ENST00000545314.1
AK4
adenylate kinase 4
chr2_-_163175133 1.11 ENST00000421365.2
ENST00000263642.2
IFIH1
interferon induced with helicase C domain 1
chrX_+_11129388 1.06 ENST00000321143.4
ENST00000380763.3
ENST00000380762.4
HCCS
holocytochrome c synthase
chr6_+_149539767 1.06 ENST00000606202.1
ENST00000536230.1
ENST00000445901.1
TAB2
RP1-111D6.3
TGF-beta activated kinase 1/MAP3K7 binding protein 2
RP1-111D6.3
chr20_+_31805131 0.98 ENST00000375454.3
ENST00000375452.3
BPIFA3
BPI fold containing family A, member 3
chr2_+_234296792 0.97 ENST00000409813.3
DGKD
diacylglycerol kinase, delta 130kDa
chr12_+_75874460 0.92 ENST00000266659.3
GLIPR1
GLI pathogenesis-related 1
chr1_-_237167718 0.90 ENST00000464121.2
MT1HL1
metallothionein 1H-like 1
chr3_-_16524357 0.87 ENST00000432519.1
RFTN1
raftlin, lipid raft linker 1
chr9_-_85882145 0.86 ENST00000328788.1
FRMD3
FERM domain containing 3
chr3_-_58613323 0.79 ENST00000474531.1
ENST00000465970.1
FAM107A
family with sequence similarity 107, member A
chr10_-_92681033 0.79 ENST00000371697.3
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr9_-_2844058 0.73 ENST00000397885.2
KIAA0020
KIAA0020
chr19_+_21324827 0.71 ENST00000600692.1
ENST00000599296.1
ENST00000594425.1
ENST00000311048.7
ZNF431
zinc finger protein 431
chr1_+_46805832 0.70 ENST00000474844.1
NSUN4
NOP2/Sun domain family, member 4
chr14_-_25078864 0.69 ENST00000216338.4
ENST00000557220.2
ENST00000382548.4
GZMH
granzyme H (cathepsin G-like 2, protein h-CCPX)
chr14_-_74417096 0.68 ENST00000286544.3
FAM161B
family with sequence similarity 161, member B
chr19_+_3762703 0.66 ENST00000589174.1
MRPL54
mitochondrial ribosomal protein L54
chr12_+_9980069 0.65 ENST00000354855.3
ENST00000324214.4
ENST00000279544.3
KLRF1
killer cell lectin-like receptor subfamily F, member 1
chr1_+_19578033 0.63 ENST00000330263.4
MRTO4
mRNA turnover 4 homolog (S. cerevisiae)
chr11_+_55029628 0.61 ENST00000417545.2
TRIM48
tripartite motif containing 48
chr11_-_133715394 0.59 ENST00000299140.3
ENST00000532889.1
SPATA19
spermatogenesis associated 19
chr11_-_113577052 0.58 ENST00000540540.1
ENST00000545579.1
ENST00000538955.1
ENST00000299882.5
TMPRSS5
transmembrane protease, serine 5
chr1_+_144811943 0.57 ENST00000281815.8
NBPF9
neuroblastoma breakpoint family, member 9
chr11_-_104827425 0.57 ENST00000393150.3
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr2_-_209054709 0.56 ENST00000449053.1
ENST00000451346.1
ENST00000341287.4
C2orf80
chromosome 2 open reading frame 80
chr4_-_170924888 0.56 ENST00000502832.1
ENST00000393704.3
MFAP3L
microfibrillar-associated protein 3-like
chr13_+_109248500 0.55 ENST00000356711.2
MYO16
myosin XVI
chr19_+_17830051 0.54 ENST00000594625.1
ENST00000324096.4
ENST00000600186.1
ENST00000597735.1
MAP1S
microtubule-associated protein 1S
chr10_-_73976025 0.53 ENST00000342444.4
ENST00000533958.1
ENST00000527593.1
ENST00000394915.3
ENST00000530461.1
ENST00000317168.6
ENST00000524829.1
ASCC1
activating signal cointegrator 1 complex subunit 1
chr4_+_156680153 0.52 ENST00000502959.1
ENST00000505764.1
ENST00000507146.1
ENST00000264424.8
ENST00000503520.1
GUCY1B3
guanylate cyclase 1, soluble, beta 3
chr1_+_148560843 0.52 ENST00000442702.2
ENST00000369187.3
NBPF15
neuroblastoma breakpoint family, member 15
chr20_-_14318248 0.52 ENST00000378053.3
ENST00000341420.4
FLRT3
fibronectin leucine rich transmembrane protein 3
chr11_-_113577014 0.52 ENST00000544634.1
ENST00000539732.1
ENST00000538770.1
ENST00000536856.1
ENST00000544476.1
TMPRSS5
transmembrane protease, serine 5
chr13_+_49280951 0.51 ENST00000282018.3
CYSLTR2
cysteinyl leukotriene receptor 2
chr11_-_123756334 0.50 ENST00000528595.1
ENST00000375026.2
TMEM225
transmembrane protein 225
chr1_-_52499443 0.48 ENST00000371614.1
KTI12
KTI12 homolog, chromatin associated (S. cerevisiae)
chr12_-_127174845 0.48 ENST00000540814.1
ENST00000541065.1
ENST00000541769.1
RP11-407A16.3
RP11-407A16.4
RP11-407A16.3
RP11-407A16.4
chr17_-_29624343 0.46 ENST00000247271.4
OMG
oligodendrocyte myelin glycoprotein
chr17_+_33448593 0.46 ENST00000158009.5
FNDC8
fibronectin type III domain containing 8
chr1_-_200379180 0.44 ENST00000294740.3
ZNF281
zinc finger protein 281
chr11_-_47400078 0.42 ENST00000378538.3
SPI1
spleen focus forming virus (SFFV) proviral integration oncogene
chr15_+_59903975 0.42 ENST00000560585.1
ENST00000396065.1
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr2_+_11864458 0.42 ENST00000396098.1
ENST00000396099.1
ENST00000425416.2
LPIN1
lipin 1
chr20_+_49575342 0.41 ENST00000244051.1
MOCS3
molybdenum cofactor synthesis 3
chr1_+_174769006 0.41 ENST00000489615.1
RABGAP1L
RAB GTPase activating protein 1-like
chr10_+_15085895 0.41 ENST00000378228.3
OLAH
oleoyl-ACP hydrolase
chr12_-_10151773 0.40 ENST00000298527.6
ENST00000348658.4
CLEC1B
C-type lectin domain family 1, member B
chr7_-_142176790 0.40 ENST00000390369.2
TRBV7-4
T cell receptor beta variable 7-4 (gene/pseudogene)
chr6_+_123317116 0.40 ENST00000275162.5
CLVS2
clavesin 2
chr20_-_23586513 0.40 ENST00000376971.3
CST9
cystatin 9 (testatin)
chr3_+_138327542 0.39 ENST00000360570.3
ENST00000393035.2
FAIM
Fas apoptotic inhibitory molecule
chr10_-_43892668 0.38 ENST00000544000.1
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr3_+_138327417 0.38 ENST00000338446.4
FAIM
Fas apoptotic inhibitory molecule
chr11_-_47399942 0.37 ENST00000227163.4
SPI1
spleen focus forming virus (SFFV) proviral integration oncogene
chr3_+_127770455 0.37 ENST00000464451.1
SEC61A1
Sec61 alpha 1 subunit (S. cerevisiae)
chr10_-_73976884 0.35 ENST00000317126.4
ENST00000545550.1
ASCC1
activating signal cointegrator 1 complex subunit 1
chr12_+_115800817 0.35 ENST00000547948.1
RP11-116D17.1
HCG2038717; Uncharacterized protein
chr11_-_47400062 0.34 ENST00000533030.1
SPI1
spleen focus forming virus (SFFV) proviral integration oncogene
chr1_-_43638168 0.33 ENST00000431635.2
EBNA1BP2
EBNA1 binding protein 2
chr6_-_130543958 0.32 ENST00000437477.2
ENST00000439090.2
SAMD3
sterile alpha motif domain containing 3
chr1_+_240255166 0.32 ENST00000319653.9
FMN2
formin 2
chr11_-_76381029 0.32 ENST00000407242.2
ENST00000421973.1
LRRC32
leucine rich repeat containing 32
chr5_-_173043591 0.31 ENST00000285908.5
ENST00000480951.1
ENST00000311086.4
BOD1
biorientation of chromosomes in cell division 1
chr19_+_55385682 0.31 ENST00000391726.3
FCAR
Fc fragment of IgA, receptor for
chr19_+_49588677 0.30 ENST00000598984.1
ENST00000598441.1
SNRNP70
small nuclear ribonucleoprotein 70kDa (U1)
chr1_-_86848760 0.29 ENST00000460698.2
ODF2L
outer dense fiber of sperm tails 2-like
chr6_-_71666732 0.29 ENST00000230053.6
B3GAT2
beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)
chr3_+_178276488 0.29 ENST00000432997.1
ENST00000455865.1
KCNMB2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr11_-_76381781 0.28 ENST00000260061.5
ENST00000404995.1
LRRC32
leucine rich repeat containing 32
chr12_-_10607084 0.27 ENST00000408006.3
ENST00000544822.1
ENST00000536188.1
KLRC1
killer cell lectin-like receptor subfamily C, member 1
chr11_+_62009653 0.26 ENST00000244926.3
SCGB1D2
secretoglobin, family 1D, member 2
chr12_+_93096619 0.26 ENST00000397833.3
C12orf74
chromosome 12 open reading frame 74
chr10_-_75401500 0.23 ENST00000359322.4
MYOZ1
myozenin 1
chr1_+_152957707 0.23 ENST00000368762.1
SPRR1A
small proline-rich protein 1A
chr6_+_28249299 0.22 ENST00000405948.2
PGBD1
piggyBac transposable element derived 1
chr8_-_93029520 0.22 ENST00000521553.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr5_+_140743859 0.22 ENST00000518069.1
PCDHGA5
protocadherin gamma subfamily A, 5
chr11_-_5255696 0.20 ENST00000292901.3
ENST00000417377.1
HBD
hemoglobin, delta
chr12_+_57810198 0.20 ENST00000598001.1
AC126614.1
HCG1818482; Uncharacterized protein
chrX_+_129040122 0.20 ENST00000394422.3
ENST00000371051.5
UTP14A
UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
chr22_-_30662828 0.19 ENST00000403463.1
ENST00000215781.2
OSM
oncostatin M
chr19_+_49588690 0.18 ENST00000221448.5
SNRNP70
small nuclear ribonucleoprotein 70kDa (U1)
chr14_+_22356029 0.18 ENST00000390437.2
TRAV12-2
T cell receptor alpha variable 12-2
chr6_+_28249332 0.17 ENST00000259883.3
PGBD1
piggyBac transposable element derived 1
chr9_-_123638633 0.17 ENST00000456291.1
PHF19
PHD finger protein 19
chr11_-_26593677 0.17 ENST00000527569.1
MUC15
mucin 15, cell surface associated
chr15_+_76196234 0.16 ENST00000540507.1
ENST00000565036.1
ENST00000569054.1
FBXO22
F-box protein 22
chrX_+_129040094 0.16 ENST00000425117.2
UTP14A
UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
chr14_+_62462541 0.16 ENST00000430451.2
SYT16
synaptotagmin XVI
chr22_-_17302589 0.16 ENST00000331428.5
XKR3
XK, Kell blood group complex subunit-related family, member 3
chr9_-_95244781 0.15 ENST00000375544.3
ENST00000375543.1
ENST00000395538.3
ENST00000450139.2
ASPN
asporin
chr1_-_200379129 0.15 ENST00000367353.1
ZNF281
zinc finger protein 281
chr14_+_21249200 0.15 ENST00000304677.2
RNASE6
ribonuclease, RNase A family, k6
chr7_+_142457315 0.15 ENST00000486171.1
ENST00000311737.7
PRSS1
protease, serine, 1 (trypsin 1)
chr1_+_12806141 0.15 ENST00000288048.5
C1orf158
chromosome 1 open reading frame 158
chr1_-_200379104 0.15 ENST00000367352.3
ZNF281
zinc finger protein 281
chr3_+_136676707 0.15 ENST00000329582.4
IL20RB
interleukin 20 receptor beta
chr12_-_110434096 0.14 ENST00000320063.9
ENST00000457474.2
ENST00000547815.1
ENST00000361006.5
GIT2
G protein-coupled receptor kinase interacting ArfGAP 2
chr12_+_55248289 0.14 ENST00000308796.6
MUCL1
mucin-like 1
chrX_-_115594160 0.14 ENST00000371894.4
CXorf61
cancer/testis antigen 83
chr16_+_12058961 0.13 ENST00000053243.1
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr3_-_185655795 0.13 ENST00000342294.4
ENST00000382191.4
ENST00000453386.2
TRA2B
transformer 2 beta homolog (Drosophila)
chr16_+_12059050 0.13 ENST00000396495.3
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr3_+_136676851 0.13 ENST00000309741.5
IL20RB
interleukin 20 receptor beta
chr3_+_174577070 0.12 ENST00000454872.1
NAALADL2
N-acetylated alpha-linked acidic dipeptidase-like 2
chr4_-_142134031 0.12 ENST00000420921.2
RNF150
ring finger protein 150
chr12_-_10605929 0.12 ENST00000347831.5
ENST00000359151.3
KLRC1
killer cell lectin-like receptor subfamily C, member 1
chr1_-_212004090 0.12 ENST00000366997.4
LPGAT1
lysophosphatidylglycerol acyltransferase 1
chr2_+_171034646 0.12 ENST00000409044.3
ENST00000408978.4
MYO3B
myosin IIIB
chr11_-_111649015 0.12 ENST00000529841.1
RP11-108O10.2
RP11-108O10.2
chr2_+_102615416 0.12 ENST00000393414.2
IL1R2
interleukin 1 receptor, type II
chr12_-_11150474 0.11 ENST00000538986.1
TAS2R20
taste receptor, type 2, member 20
chr4_-_74486217 0.11 ENST00000335049.5
ENST00000307439.5
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr6_-_15548591 0.11 ENST00000509674.1
DTNBP1
dystrobrevin binding protein 1
chr11_-_26593649 0.09 ENST00000455601.2
MUC15
mucin 15, cell surface associated
chr2_+_171036635 0.09 ENST00000484338.2
ENST00000334231.6
MYO3B
myosin IIIB
chr17_-_15168624 0.08 ENST00000312280.3
ENST00000494511.1
ENST00000580584.1
PMP22
peripheral myelin protein 22
chr1_-_112106556 0.08 ENST00000443498.1
ADORA3
adenosine A3 receptor
chr7_-_105029812 0.07 ENST00000482897.1
SRPK2
SRSF protein kinase 2
chr6_-_46048116 0.07 ENST00000185206.6
CLIC5
chloride intracellular channel 5
chr20_-_49575058 0.07 ENST00000371584.4
ENST00000371583.5
ENST00000413082.1
DPM1
dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
chr3_-_33686925 0.06 ENST00000485378.2
ENST00000313350.6
ENST00000487200.1
CLASP2
cytoplasmic linker associated protein 2
chr7_-_92848858 0.06 ENST00000440868.1
HEPACAM2
HEPACAM family member 2
chr7_-_92848878 0.06 ENST00000341723.4
HEPACAM2
HEPACAM family member 2
chr10_+_78078088 0.06 ENST00000496424.2
C10orf11
chromosome 10 open reading frame 11
chr11_+_125496619 0.05 ENST00000532669.1
ENST00000278916.3
CHEK1
checkpoint kinase 1
chr11_-_18062872 0.04 ENST00000250018.2
TPH1
tryptophan hydroxylase 1
chr20_-_49575081 0.04 ENST00000371588.5
ENST00000371582.4
DPM1
dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
chr11_-_5255861 0.04 ENST00000380299.3
HBD
hemoglobin, delta
chr11_+_125496124 0.04 ENST00000533778.2
ENST00000534070.1
CHEK1
checkpoint kinase 1
chr9_-_114090713 0.04 ENST00000302681.1
ENST00000374428.1
OR2K2
olfactory receptor, family 2, subfamily K, member 2
chr17_-_38821373 0.02 ENST00000394052.3
KRT222
keratin 222
chr20_-_48747662 0.02 ENST00000371656.2
TMEM189
transmembrane protein 189
chr1_+_202789394 0.02 ENST00000330493.5
RP11-480I12.4
Putative inactive alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein LOC641515
chr16_-_11876408 0.01 ENST00000396516.2
ZC3H7A
zinc finger CCCH-type containing 7A
chr1_+_152975488 0.01 ENST00000542696.1
SPRR3
small proline-rich protein 3
chr4_-_74486109 0.01 ENST00000395777.2
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr4_-_74486347 0.00 ENST00000342081.3
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr6_+_26183958 0.00 ENST00000356530.3
HIST1H2BE
histone cluster 1, H2be

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.5 GO:0070340 central nervous system myelin formation(GO:0032289) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.7 2.7 GO:0052250 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.3 3.0 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.3 1.1 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.3 1.1 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.1 0.4 GO:0018307 tRNA wobble position uridine thiolation(GO:0002143) enzyme active site formation(GO:0018307)
0.1 0.4 GO:0039019 pronephric nephron development(GO:0039019)
0.1 0.9 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.1 0.3 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.1 0.5 GO:0061083 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.1 0.7 GO:0042256 mature ribosome assembly(GO:0042256)
0.1 0.5 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.1 0.3 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.1 0.5 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.1 0.9 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.1 0.4 GO:0006642 triglyceride mobilization(GO:0006642)
0.1 0.6 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.5 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 1.2 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.5 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 0.2 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 0.8 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 1.0 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.6 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.2 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.1 GO:0032690 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.0 0.8 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 1.1 GO:0017004 cytochrome complex assembly(GO:0017004)
0.0 1.1 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.0 0.4 GO:0030220 platelet formation(GO:0030220)
0.0 0.1 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.1 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 1.3 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.9 GO:0060338 regulation of type I interferon-mediated signaling pathway(GO:0060338)
0.0 1.9 GO:0070126 mitochondrial translational termination(GO:0070126)
0.0 0.6 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.2 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.2 GO:0015671 oxygen transport(GO:0015671)
0.0 0.7 GO:0019835 cytolysis(GO:0019835)
0.0 0.0 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.0 0.3 GO:0002385 mucosal immune response(GO:0002385)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.5 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.1 1.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 1.3 GO:0032433 filopodium tip(GO:0032433)
0.1 0.6 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.1 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 2.6 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.5 GO:0000243 commitment complex(GO:0000243)
0.0 0.5 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.2 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.5 GO:0002080 acrosomal membrane(GO:0002080)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.0 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.4 3.5 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.3 0.8 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.2 0.7 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.1 1.3 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 0.4 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 0.4 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 1.1 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.4 GO:0016295 oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297)
0.1 0.3 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 0.5 GO:0004974 leukotriene receptor activity(GO:0004974)
0.1 0.8 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 0.4 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.1 0.3 GO:0019862 IgA binding(GO:0019862)
0.1 0.9 GO:0005131 growth hormone receptor binding(GO:0005131)
0.1 0.4 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.1 3.8 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 0.7 GO:0032393 MHC class I receptor activity(GO:0032393)
0.1 1.0 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.5 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.3 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.2 GO:0051373 FATZ binding(GO:0051373)
0.0 0.1 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.5 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.6 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.5 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 2.0 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.2 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 1.0 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.4 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.5 GO:0048487 beta-tubulin binding(GO:0048487)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 0.9 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 1.1 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.3 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.1 PID IL4 2PATHWAY IL4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.5 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.1 1.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 1.1 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.9 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.5 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 1.0 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.3 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.4 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.6 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.8 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.7 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression