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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for SOX11

Z-value: 0.61

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Transcription factors associated with SOX11

Gene Symbol Gene ID Gene Info
SOX11
ENSG00000176887.5 SRY-box transcription factor 11

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX11hg19_v2_chr2_+_5832799_5832799-0.301.5e-01Click!

Activity profile of SOX11 motif

Sorted Z-values of SOX11 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_225266743 6.17 ENST00000409685.3
FAM124B
family with sequence similarity 124B
chr2_-_225266711 4.88 ENST00000389874.3
FAM124B
family with sequence similarity 124B
chr3_-_18466026 2.69 ENST00000417717.2
SATB1
SATB homeobox 1
chr9_+_75766763 1.72 ENST00000456643.1
ENST00000415424.1
ANXA1
annexin A1
chr4_-_90759440 1.34 ENST00000336904.3
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr11_+_92085262 1.22 ENST00000298047.6
ENST00000409404.2
ENST00000541502.1
FAT3
FAT atypical cadherin 3
chr12_+_32655048 1.12 ENST00000427716.2
ENST00000266482.3
FGD4
FYVE, RhoGEF and PH domain containing 4
chr17_-_66951474 1.09 ENST00000269080.2
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr6_-_76072719 1.07 ENST00000370020.1
FILIP1
filamin A interacting protein 1
chr9_+_71986182 0.79 ENST00000303068.7
FAM189A2
family with sequence similarity 189, member A2
chr12_+_60058458 0.79 ENST00000548610.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr4_-_110624564 0.79 ENST00000352981.3
ENST00000265164.2
ENST00000505486.1
CASP6
caspase 6, apoptosis-related cysteine peptidase
chr21_+_17792672 0.64 ENST00000602620.1
LINC00478
long intergenic non-protein coding RNA 478
chr13_+_78315295 0.62 ENST00000351546.3
SLAIN1
SLAIN motif family, member 1
chr2_+_138721850 0.53 ENST00000329366.4
ENST00000280097.3
HNMT
histamine N-methyltransferase
chr5_+_53813536 0.52 ENST00000343017.6
ENST00000381410.4
ENST00000326277.3
SNX18
sorting nexin 18
chr12_-_11287243 0.49 ENST00000539585.1
TAS2R30
taste receptor, type 2, member 30
chr2_+_207804278 0.48 ENST00000272852.3
CPO
carboxypeptidase O
chr5_+_55149150 0.47 ENST00000297015.3
IL31RA
interleukin 31 receptor A
chr13_+_78315466 0.47 ENST00000314070.5
ENST00000462234.1
SLAIN1
SLAIN motif family, member 1
chr5_+_140213815 0.41 ENST00000525929.1
ENST00000378125.3
PCDHA7
protocadherin alpha 7
chr11_+_7110165 0.41 ENST00000306904.5
RBMXL2
RNA binding motif protein, X-linked-like 2
chrX_+_102192200 0.39 ENST00000218249.5
RAB40AL
RAB40A, member RAS oncogene family-like
chr13_-_103019744 0.38 ENST00000437115.2
FGF14-IT1
FGF14 intronic transcript 1 (non-protein coding)
chr5_+_140248518 0.38 ENST00000398640.2
PCDHA11
protocadherin alpha 11
chr15_+_49447947 0.38 ENST00000327171.3
ENST00000560654.1
GALK2
galactokinase 2
chrX_-_100548045 0.38 ENST00000372907.3
ENST00000372905.2
TAF7L
TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa
chr1_+_145524891 0.37 ENST00000369304.3
ITGA10
integrin, alpha 10
chr6_-_99873145 0.37 ENST00000369239.5
ENST00000438806.1
PNISR
PNN-interacting serine/arginine-rich protein
chr2_-_37068530 0.35 ENST00000593798.1
AC007382.1
Uncharacterized protein
chr17_+_38474489 0.35 ENST00000394089.2
ENST00000425707.3
RARA
retinoic acid receptor, alpha
chr2_+_138722028 0.34 ENST00000280096.5
HNMT
histamine N-methyltransferase
chr1_-_205744205 0.33 ENST00000446390.2
RAB7L1
RAB7, member RAS oncogene family-like 1
chr10_+_35456444 0.33 ENST00000361599.4
CREM
cAMP responsive element modulator
chr5_-_54468974 0.33 ENST00000381375.2
ENST00000296733.1
ENST00000322374.6
ENST00000334206.5
ENST00000331730.3
CDC20B
cell division cycle 20B
chr8_+_104831554 0.33 ENST00000408894.2
RIMS2
regulating synaptic membrane exocytosis 2
chrX_-_32173579 0.32 ENST00000359836.1
ENST00000343523.2
ENST00000378707.3
ENST00000541735.1
ENST00000474231.1
DMD
dystrophin
chr6_-_30585009 0.32 ENST00000376511.2
PPP1R10
protein phosphatase 1, regulatory subunit 10
chr15_-_37392086 0.32 ENST00000561208.1
MEIS2
Meis homeobox 2
chr12_+_28410128 0.32 ENST00000381259.1
ENST00000381256.1
CCDC91
coiled-coil domain containing 91
chr17_+_47448102 0.32 ENST00000576461.1
RP11-81K2.1
Uncharacterized protein
chr14_+_21156915 0.31 ENST00000397990.4
ENST00000555597.1
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr11_+_22688150 0.31 ENST00000454584.2
GAS2
growth arrest-specific 2
chr4_+_110749143 0.31 ENST00000317735.4
RRH
retinal pigment epithelium-derived rhodopsin homolog
chr2_+_109237717 0.31 ENST00000409441.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr1_+_65730385 0.30 ENST00000263441.7
ENST00000395325.3
DNAJC6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr18_+_46065393 0.30 ENST00000256413.3
CTIF
CBP80/20-dependent translation initiation factor
chr6_-_52705641 0.30 ENST00000370989.2
GSTA5
glutathione S-transferase alpha 5
chr2_+_179318295 0.30 ENST00000442710.1
DFNB59
deafness, autosomal recessive 59
chr20_+_18794370 0.28 ENST00000377428.2
SCP2D1
SCP2 sterol-binding domain containing 1
chr3_+_113616317 0.28 ENST00000440446.2
ENST00000488680.1
GRAMD1C
GRAM domain containing 1C
chr1_+_196621002 0.28 ENST00000367429.4
ENST00000439155.2
CFH
complement factor H
chr1_+_214776516 0.28 ENST00000366955.3
CENPF
centromere protein F, 350/400kDa
chr18_+_46065483 0.27 ENST00000382998.4
CTIF
CBP80/20-dependent translation initiation factor
chr1_-_111061797 0.27 ENST00000369771.2
KCNA10
potassium voltage-gated channel, shaker-related subfamily, member 10
chr4_+_130017268 0.26 ENST00000425929.1
ENST00000508673.1
ENST00000508622.1
C4orf33
chromosome 4 open reading frame 33
chr1_-_205744574 0.26 ENST00000367139.3
ENST00000235932.4
ENST00000437324.2
ENST00000414729.1
RAB7L1
RAB7, member RAS oncogene family-like 1
chr4_+_88754113 0.25 ENST00000560249.1
ENST00000540395.1
ENST00000511670.1
ENST00000361056.3
MEPE
matrix extracellular phosphoglycoprotein
chr1_-_24469602 0.25 ENST00000270800.1
IL22RA1
interleukin 22 receptor, alpha 1
chr18_+_7754957 0.25 ENST00000400053.4
PTPRM
protein tyrosine phosphatase, receptor type, M
chr2_-_71222466 0.25 ENST00000606025.1
AC007040.11
Uncharacterized protein
chr8_-_54752406 0.24 ENST00000520188.1
ATP6V1H
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr1_-_197169672 0.24 ENST00000367405.4
ZBTB41
zinc finger and BTB domain containing 41
chr10_-_127505167 0.24 ENST00000368786.1
UROS
uroporphyrinogen III synthase
chr4_+_88754069 0.24 ENST00000395102.4
ENST00000497649.2
MEPE
matrix extracellular phosphoglycoprotein
chr14_-_36789783 0.24 ENST00000605579.1
ENST00000604336.1
ENST00000359527.7
ENST00000603139.1
ENST00000318473.7
MBIP
MAP3K12 binding inhibitory protein 1
chr4_-_170679024 0.23 ENST00000393381.2
C4orf27
chromosome 4 open reading frame 27
chr14_-_36789865 0.23 ENST00000416007.4
MBIP
MAP3K12 binding inhibitory protein 1
chr17_-_34344991 0.23 ENST00000591423.1
CCL23
chemokine (C-C motif) ligand 23
chr2_+_102927962 0.22 ENST00000233954.1
ENST00000393393.3
ENST00000410040.1
IL1RL1
IL18R1
interleukin 1 receptor-like 1
interleukin 18 receptor 1
chr3_-_133380731 0.22 ENST00000260810.5
TOPBP1
topoisomerase (DNA) II binding protein 1
chr9_-_95166841 0.22 ENST00000262551.4
OGN
osteoglycin
chr1_-_241799232 0.20 ENST00000366553.1
CHML
choroideremia-like (Rab escort protein 2)
chr7_-_122635754 0.20 ENST00000249284.2
TAS2R16
taste receptor, type 2, member 16
chr15_+_45028753 0.20 ENST00000338264.4
TRIM69
tripartite motif containing 69
chr1_+_93645314 0.20 ENST00000343253.7
CCDC18
coiled-coil domain containing 18
chr9_-_114521783 0.20 ENST00000394779.3
ENST00000394777.4
C9orf84
chromosome 9 open reading frame 84
chr22_+_24407776 0.20 ENST00000405822.2
CABIN1
calcineurin binding protein 1
chr13_-_30424821 0.19 ENST00000380680.4
UBL3
ubiquitin-like 3
chr17_-_34345002 0.19 ENST00000293280.2
CCL23
chemokine (C-C motif) ligand 23
chrX_+_27826107 0.17 ENST00000356790.2
MAGEB10
melanoma antigen family B, 10
chr5_+_148521381 0.17 ENST00000504238.1
ABLIM3
actin binding LIM protein family, member 3
chr3_+_101504200 0.17 ENST00000422132.1
NXPE3
neurexophilin and PC-esterase domain family, member 3
chr17_+_35732955 0.17 ENST00000300618.4
C17orf78
chromosome 17 open reading frame 78
chr8_+_9413410 0.16 ENST00000520408.1
ENST00000310430.6
ENST00000522110.1
TNKS
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr17_+_35732916 0.16 ENST00000586700.1
C17orf78
chromosome 17 open reading frame 78
chr15_+_45028719 0.16 ENST00000560442.1
ENST00000558329.1
ENST00000561043.1
TRIM69
tripartite motif containing 69
chr2_-_219157250 0.15 ENST00000434015.2
ENST00000444183.1
ENST00000420341.1
ENST00000453281.1
ENST00000258412.3
ENST00000440422.1
TMBIM1
transmembrane BAX inhibitor motif containing 1
chr12_+_41221794 0.15 ENST00000547849.1
CNTN1
contactin 1
chr1_+_196621156 0.15 ENST00000359637.2
CFH
complement factor H
chr2_-_20251744 0.15 ENST00000175091.4
LAPTM4A
lysosomal protein transmembrane 4 alpha
chr6_+_53883790 0.15 ENST00000509997.1
MLIP
muscular LMNA-interacting protein
chr18_+_22040620 0.15 ENST00000426880.2
HRH4
histamine receptor H4
chr10_-_5446786 0.14 ENST00000479328.1
ENST00000380419.3
TUBAL3
tubulin, alpha-like 3
chr15_-_64673665 0.14 ENST00000300035.4
KIAA0101
KIAA0101
chrX_+_130192318 0.14 ENST00000370922.1
ARHGAP36
Rho GTPase activating protein 36
chr7_+_90012986 0.14 ENST00000416322.1
CLDN12
claudin 12
chr1_+_198608146 0.14 ENST00000367376.2
ENST00000352140.3
ENST00000594404.1
ENST00000598951.1
ENST00000530727.1
ENST00000442510.2
ENST00000367367.4
ENST00000348564.6
ENST00000367364.1
ENST00000413409.2
PTPRC
protein tyrosine phosphatase, receptor type, C
chr15_-_78913628 0.14 ENST00000348639.3
CHRNA3
cholinergic receptor, nicotinic, alpha 3 (neuronal)
chr4_+_159443090 0.13 ENST00000343542.5
ENST00000470033.1
RXFP1
relaxin/insulin-like family peptide receptor 1
chr12_-_122879969 0.12 ENST00000540304.1
CLIP1
CAP-GLY domain containing linker protein 1
chr10_+_5238793 0.11 ENST00000263126.1
AKR1C4
aldo-keto reductase family 1, member C4
chr10_+_32873190 0.11 ENST00000375025.4
C10orf68
Homo sapiens coiled-coil domain containing 7 (CCDC7), transcript variant 5, mRNA.
chr11_-_64684672 0.11 ENST00000377264.3
ENST00000421419.2
ATG2A
autophagy related 2A
chr12_-_122240792 0.10 ENST00000545885.1
ENST00000542933.1
ENST00000428029.2
ENST00000541694.1
ENST00000536662.1
ENST00000535643.1
ENST00000541657.1
AC084018.1
RHOF
AC084018.1
ras homolog family member F (in filopodia)
chr5_+_140207536 0.10 ENST00000529310.1
ENST00000527624.1
PCDHA6
protocadherin alpha 6
chrX_+_24483338 0.10 ENST00000379162.4
ENST00000441463.2
PDK3
pyruvate dehydrogenase kinase, isozyme 3
chr9_+_27109133 0.10 ENST00000519097.1
ENST00000380036.4
TEK
TEK tyrosine kinase, endothelial
chr18_+_22040593 0.10 ENST00000256906.4
HRH4
histamine receptor H4
chr5_-_86534822 0.09 ENST00000445770.2
AC008394.1
Uncharacterized protein
chrX_+_100645812 0.09 ENST00000427805.2
ENST00000553110.3
ENST00000392994.3
ENST00000409338.1
ENST00000409170.3
RPL36A
RPL36A-HNRNPH2
ribosomal protein L36a
RPL36A-HNRNPH2 readthrough
chr6_+_53883708 0.09 ENST00000514921.1
ENST00000274897.5
ENST00000370877.2
MLIP
muscular LMNA-interacting protein
chrX_-_7895755 0.09 ENST00000444736.1
ENST00000537427.1
ENST00000442940.1
PNPLA4
patatin-like phospholipase domain containing 4
chr7_-_81399355 0.09 ENST00000457544.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr6_-_46048116 0.09 ENST00000185206.6
CLIC5
chloride intracellular channel 5
chr7_-_82792215 0.09 ENST00000333891.9
ENST00000423517.2
PCLO
piccolo presynaptic cytomatrix protein
chr6_-_133055815 0.07 ENST00000509351.1
ENST00000417437.2
ENST00000414302.2
ENST00000423615.2
ENST00000427187.2
ENST00000275223.3
ENST00000519686.2
VNN3
vanin 3
chr8_-_25281747 0.07 ENST00000421054.2
GNRH1
gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
chr10_-_95242044 0.07 ENST00000371501.4
ENST00000371502.4
ENST00000371489.1
MYOF
myoferlin
chr4_+_141294628 0.07 ENST00000512749.1
ENST00000608372.1
ENST00000506597.1
ENST00000394201.4
ENST00000510586.1
SCOC
short coiled-coil protein
chr2_+_47596287 0.07 ENST00000263735.4
EPCAM
epithelial cell adhesion molecule
chr14_+_39703112 0.06 ENST00000555143.1
ENST00000280082.3
MIA2
melanoma inhibitory activity 2
chr3_-_49967292 0.06 ENST00000455683.2
MON1A
MON1 secretory trafficking family member A
chr4_+_159442878 0.06 ENST00000307765.5
ENST00000423548.1
RXFP1
relaxin/insulin-like family peptide receptor 1
chr15_-_64673630 0.06 ENST00000558008.1
ENST00000559519.1
ENST00000380258.2
KIAA0101
KIAA0101
chr10_-_90611566 0.06 ENST00000371930.4
ANKRD22
ankyrin repeat domain 22
chr6_-_32977345 0.06 ENST00000450833.2
ENST00000374813.1
ENST00000229829.5
HLA-DOA
major histocompatibility complex, class II, DO alpha
chr3_-_47950745 0.05 ENST00000429422.1
MAP4
microtubule-associated protein 4
chr10_-_95241951 0.05 ENST00000358334.5
ENST00000359263.4
ENST00000371488.3
MYOF
myoferlin
chr3_-_55001115 0.05 ENST00000493075.1
LRTM1
leucine-rich repeats and transmembrane domains 1
chr5_-_169725231 0.05 ENST00000046794.5
LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr11_-_118047376 0.05 ENST00000278947.5
SCN2B
sodium channel, voltage-gated, type II, beta subunit
chr3_+_69812701 0.04 ENST00000472437.1
MITF
microphthalmia-associated transcription factor
chrM_+_8527 0.04 ENST00000361899.2
MT-ATP6
mitochondrially encoded ATP synthase 6
chr4_+_71337834 0.04 ENST00000304887.5
MUC7
mucin 7, secreted
chr8_-_37707356 0.04 ENST00000520601.1
ENST00000521170.1
ENST00000220659.6
BRF2
BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
chr20_-_32308028 0.04 ENST00000409299.3
ENST00000217398.3
ENST00000344022.3
PXMP4
peroxisomal membrane protein 4, 24kDa
chr12_-_772901 0.04 ENST00000305108.4
NINJ2
ninjurin 2
chr17_+_62461569 0.03 ENST00000603557.1
ENST00000605096.1
MILR1
mast cell immunoglobulin-like receptor 1
chrX_+_107288197 0.03 ENST00000415430.3
VSIG1
V-set and immunoglobulin domain containing 1
chr2_-_176046391 0.03 ENST00000392541.3
ENST00000409194.1
ATP5G3
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
chr6_-_31125850 0.03 ENST00000507751.1
ENST00000448162.2
ENST00000502557.1
ENST00000503420.1
ENST00000507892.1
ENST00000507226.1
ENST00000513222.1
ENST00000503934.1
ENST00000396263.2
ENST00000508683.1
ENST00000428174.1
ENST00000448141.2
ENST00000507829.1
ENST00000455279.2
ENST00000376266.5
CCHCR1
coiled-coil alpha-helical rod protein 1
chr1_-_115292591 0.03 ENST00000438362.2
CSDE1
cold shock domain containing E1, RNA-binding
chr8_+_41386761 0.03 ENST00000523277.2
GINS4
GINS complex subunit 4 (Sld5 homolog)
chr5_+_108083517 0.03 ENST00000281092.4
ENST00000536402.1
FER
fer (fps/fes related) tyrosine kinase
chr5_+_3596168 0.03 ENST00000302006.3
IRX1
iroquois homeobox 1
chr5_+_179159813 0.03 ENST00000292599.3
MAML1
mastermind-like 1 (Drosophila)
chr12_-_10959892 0.03 ENST00000240615.2
TAS2R8
taste receptor, type 2, member 8
chr3_+_113251143 0.02 ENST00000264852.4
ENST00000393830.3
SIDT1
SID1 transmembrane family, member 1
chr19_-_14911023 0.02 ENST00000248073.2
OR7C1
olfactory receptor, family 7, subfamily C, member 1
chr7_-_112635675 0.02 ENST00000447785.1
ENST00000451962.1
AC018464.3
AC018464.3
chr1_-_120935894 0.02 ENST00000369383.4
ENST00000369384.4
FCGR1B
Fc fragment of IgG, high affinity Ib, receptor (CD64)
chr14_+_39703084 0.02 ENST00000553728.1
RP11-407N17.3
cTAGE family member 5 isoform 4
chr6_+_26183958 0.02 ENST00000356530.3
HIST1H2BE
histone cluster 1, H2be
chr9_-_21142144 0.01 ENST00000380229.2
IFNW1
interferon, omega 1
chr1_+_207038699 0.01 ENST00000367098.1
IL20
interleukin 20
chr14_-_92198403 0.01 ENST00000553329.1
ENST00000256343.3
CATSPERB
catsper channel auxiliary subunit beta
chr13_-_99630233 0.01 ENST00000376460.1
ENST00000442173.1
DOCK9
dedicator of cytokinesis 9
chr11_+_61976137 0.01 ENST00000244930.4
SCGB2A1
secretoglobin, family 2A, member 1
chr11_-_95657231 0.01 ENST00000409459.1
ENST00000352297.7
ENST00000393223.3
ENST00000346299.5
MTMR2
myotubularin related protein 2
chrX_+_107288239 0.00 ENST00000217957.5
VSIG1
V-set and immunoglobulin domain containing 1
chr4_+_72204755 0.00 ENST00000512686.1
ENST00000340595.3
SLC4A4
solute carrier family 4 (sodium bicarbonate cotransporter), member 4
chr14_+_96949319 0.00 ENST00000554706.1
AK7
adenylate kinase 7
chr6_-_89927151 0.00 ENST00000454853.2
GABRR1
gamma-aminobutyric acid (GABA) A receptor, rho 1
chr8_+_105352050 0.00 ENST00000297581.2
DCSTAMP
dendrocyte expressed seven transmembrane protein

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX11

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0014839 myoblast migration involved in skeletal muscle regeneration(GO:0014839)
0.3 1.3 GO:1903282 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.1 2.7 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.9 GO:0001692 histamine metabolic process(GO:0001692)
0.1 0.5 GO:0007231 osmosensory signaling pathway(GO:0007231)
0.1 0.8 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1 0.8 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.1 1.1 GO:0042908 xenobiotic transport(GO:0042908)
0.1 0.4 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.1 0.2 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.1 0.3 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.5 GO:0036089 cleavage furrow formation(GO:0036089)
0.0 0.2 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875) protein auto-ADP-ribosylation(GO:0070213)
0.0 0.2 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.0 0.1 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.0 0.3 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.3 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.3 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.5 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.1 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.0 0.1 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.2 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.5 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.1 GO:1990637 response to prolactin(GO:1990637)
0.0 0.1 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.0 0.2 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.3 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.7 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.2 GO:0071351 interleukin-18-mediated signaling pathway(GO:0035655) cellular response to interleukin-18(GO:0071351)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.4 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.1 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.2 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.1 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 1.1 GO:0046847 filopodium assembly(GO:0046847)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232) extrinsic component of endosome membrane(GO:0031313)
0.1 0.4 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.1 0.3 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.1 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 2.5 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.2 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 1.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.3 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.3 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.5 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.3 GO:0045120 pronucleus(GO:0045120)
0.0 0.1 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.0 GO:0097679 other organism cytoplasm(GO:0097679)
0.0 0.2 GO:0001673 male germ cell nucleus(GO:0001673)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.2 1.7 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.2 0.8 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.2 0.5 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.1 0.4 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.1 1.1 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 0.5 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.2 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.1 0.4 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 0.4 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 0.3 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.3 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.3 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.7 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.8 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.3 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.4 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.3 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.8 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.3 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 3.8 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 1.1 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.3 REACTOME OPSINS Genes involved in Opsins
0.0 1.4 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol