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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for SOX13_SOX12

Z-value: 0.81

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Transcription factors associated with SOX13_SOX12

Gene Symbol Gene ID Gene Info
SOX13
ENSG00000143842.10 SRY-box transcription factor 13
SOX12
ENSG00000177732.6 SRY-box transcription factor 12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX12hg19_v2_chr20_+_306221_306239-0.601.4e-03Click!
SOX13hg19_v2_chr1_+_204042723_204042784-0.423.8e-02Click!

Activity profile of SOX13_SOX12 motif

Sorted Z-values of SOX13_SOX12 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_102928009 2.70 ENST00000404917.2
ENST00000447231.1
IL1RL1
interleukin 1 receptor-like 1
chr18_-_70211691 2.51 ENST00000269503.4
CBLN2
cerebellin 2 precursor
chr11_+_19798964 2.38 ENST00000527559.2
NAV2
neuron navigator 2
chr11_+_19799327 2.35 ENST00000540292.1
NAV2
neuron navigator 2
chr17_+_41158742 2.02 ENST00000415816.2
ENST00000438323.2
IFI35
interferon-induced protein 35
chr2_-_202562716 2.00 ENST00000428900.2
MPP4
membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
chr2_-_202562774 1.91 ENST00000396886.3
ENST00000409143.1
MPP4
membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
chr11_-_102651343 1.82 ENST00000279441.4
ENST00000539681.1
MMP10
matrix metallopeptidase 10 (stromelysin 2)
chr4_-_74864386 1.77 ENST00000296027.4
CXCL5
chemokine (C-X-C motif) ligand 5
chr21_+_43619796 1.62 ENST00000398457.2
ABCG1
ATP-binding cassette, sub-family G (WHITE), member 1
chr9_+_5510492 1.62 ENST00000397745.2
PDCD1LG2
programmed cell death 1 ligand 2
chr9_+_5510558 1.59 ENST00000397747.3
PDCD1LG2
programmed cell death 1 ligand 2
chr7_-_115608304 1.53 ENST00000457268.1
TFEC
transcription factor EC
chr2_+_103035102 1.44 ENST00000264260.2
IL18RAP
interleukin 18 receptor accessory protein
chr1_+_165797024 1.38 ENST00000372212.4
UCK2
uridine-cytidine kinase 2
chr5_+_35856951 1.34 ENST00000303115.3
ENST00000343305.4
ENST00000506850.1
ENST00000511982.1
IL7R
interleukin 7 receptor
chr6_-_89927151 1.34 ENST00000454853.2
GABRR1
gamma-aminobutyric acid (GABA) A receptor, rho 1
chr1_-_8000872 1.32 ENST00000377507.3
TNFRSF9
tumor necrosis factor receptor superfamily, member 9
chr4_+_146539415 1.29 ENST00000281317.5
MMAA
methylmalonic aciduria (cobalamin deficiency) cblA type
chr2_-_202563414 1.18 ENST00000409474.3
ENST00000315506.7
ENST00000359962.5
MPP4
membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
chr6_+_26440700 1.08 ENST00000494393.1
ENST00000482451.1
ENST00000244519.2
ENST00000339789.4
ENST00000471353.1
ENST00000361232.3
ENST00000487627.1
ENST00000496719.1
ENST00000490254.1
ENST00000487272.1
BTN3A3
butyrophilin, subfamily 3, member A3
chr17_+_53828333 1.05 ENST00000268896.5
PCTP
phosphatidylcholine transfer protein
chr11_-_85393886 1.03 ENST00000534224.1
CREBZF
CREB/ATF bZIP transcription factor
chr11_+_93479588 1.02 ENST00000526335.1
C11orf54
chromosome 11 open reading frame 54
chr10_-_24770632 1.01 ENST00000596413.1
AL353583.1
AL353583.1
chr5_+_54320078 1.00 ENST00000231009.2
GZMK
granzyme K (granzyme 3; tryptase II)
chr15_-_80263506 0.99 ENST00000335661.6
BCL2A1
BCL2-related protein A1
chr11_-_85430163 0.99 ENST00000529581.1
ENST00000533577.1
SYTL2
synaptotagmin-like 2
chr11_-_85430204 0.98 ENST00000389958.3
ENST00000527794.1
SYTL2
synaptotagmin-like 2
chr7_-_121944491 0.96 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1
FEZ family zinc finger 1
chr2_+_143635067 0.94 ENST00000264170.4
KYNU
kynureninase
chr4_+_154622652 0.94 ENST00000260010.6
TLR2
toll-like receptor 2
chr11_-_51412448 0.92 ENST00000319760.6
OR4A5
olfactory receptor, family 4, subfamily A, member 5
chr19_-_7553889 0.92 ENST00000221480.1
PEX11G
peroxisomal biogenesis factor 11 gamma
chr1_+_244515930 0.92 ENST00000366537.1
ENST00000308105.4
C1orf100
chromosome 1 open reading frame 100
chr12_+_113354341 0.91 ENST00000553152.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr11_-_85430088 0.90 ENST00000533057.1
ENST00000533892.1
SYTL2
synaptotagmin-like 2
chr18_-_53804580 0.89 ENST00000590484.1
ENST00000589293.1
ENST00000587904.1
ENST00000591974.1
RP11-456O19.4
RP11-456O19.4
chr6_-_128841503 0.88 ENST00000368215.3
ENST00000532331.1
ENST00000368213.5
ENST00000368207.3
ENST00000525459.1
ENST00000368210.3
ENST00000368226.4
ENST00000368227.3
PTPRK
protein tyrosine phosphatase, receptor type, K
chr3_-_123339343 0.88 ENST00000578202.1
MYLK
myosin light chain kinase
chr3_-_122283424 0.84 ENST00000477522.2
ENST00000360356.2
PARP9
poly (ADP-ribose) polymerase family, member 9
chr4_+_70916119 0.83 ENST00000246896.3
ENST00000511674.1
HTN1
histatin 1
chr3_-_107777208 0.82 ENST00000398258.3
CD47
CD47 molecule
chr6_-_11779014 0.81 ENST00000229583.5
ADTRP
androgen-dependent TFPI-regulating protein
chr5_-_124081008 0.80 ENST00000306315.5
ZNF608
zinc finger protein 608
chr11_+_55029628 0.79 ENST00000417545.2
TRIM48
tripartite motif containing 48
chr15_+_69857515 0.79 ENST00000559477.1
RP11-279F6.1
RP11-279F6.1
chr19_+_21324827 0.77 ENST00000600692.1
ENST00000599296.1
ENST00000594425.1
ENST00000311048.7
ZNF431
zinc finger protein 431
chr11_+_5710919 0.77 ENST00000379965.3
ENST00000425490.1
TRIM22
tripartite motif containing 22
chr3_-_49967292 0.75 ENST00000455683.2
MON1A
MON1 secretory trafficking family member A
chr5_-_96518907 0.75 ENST00000508447.1
ENST00000283109.3
RIOK2
RIO kinase 2
chr6_-_134639180 0.72 ENST00000367858.5
SGK1
serum/glucocorticoid regulated kinase 1
chr6_-_25830785 0.68 ENST00000468082.1
SLC17A1
solute carrier family 17 (organic anion transporter), member 1
chr8_-_13372253 0.68 ENST00000316609.5
DLC1
deleted in liver cancer 1
chr5_-_172756506 0.66 ENST00000265087.4
STC2
stanniocalcin 2
chr4_+_36283213 0.66 ENST00000357504.3
DTHD1
death domain containing 1
chr8_-_13134045 0.65 ENST00000512044.2
DLC1
deleted in liver cancer 1
chr2_+_152214098 0.64 ENST00000243347.3
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr6_-_11779174 0.63 ENST00000379413.2
ADTRP
androgen-dependent TFPI-regulating protein
chr1_-_243418344 0.63 ENST00000366542.1
CEP170
centrosomal protein 170kDa
chr3_-_142166904 0.60 ENST00000264951.4
XRN1
5'-3' exoribonuclease 1
chr17_+_47448102 0.59 ENST00000576461.1
RP11-81K2.1
Uncharacterized protein
chr4_+_74301880 0.58 ENST00000395792.2
ENST00000226359.2
AFP
alpha-fetoprotein
chr1_-_243418621 0.58 ENST00000366544.1
ENST00000366543.1
CEP170
centrosomal protein 170kDa
chr11_+_35201826 0.57 ENST00000531873.1
CD44
CD44 molecule (Indian blood group)
chr8_+_117950422 0.57 ENST00000378279.3
AARD
alanine and arginine rich domain containing protein
chr5_+_121465207 0.53 ENST00000296600.4
ZNF474
zinc finger protein 474
chr2_-_216878305 0.53 ENST00000263268.6
MREG
melanoregulin
chr4_-_105416039 0.53 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr4_-_122085469 0.52 ENST00000057513.3
TNIP3
TNFAIP3 interacting protein 3
chr4_+_100432161 0.51 ENST00000326581.4
ENST00000514652.1
C4orf17
chromosome 4 open reading frame 17
chr1_-_89488510 0.51 ENST00000564665.1
ENST00000370481.4
GBP3
guanylate binding protein 3
chr4_+_165675269 0.51 ENST00000507311.1
RP11-294O2.2
RP11-294O2.2
chr17_+_53828381 0.51 ENST00000576183.1
PCTP
phosphatidylcholine transfer protein
chr19_+_21264980 0.50 ENST00000596053.1
ENST00000597086.1
ENST00000596143.1
ENST00000596367.1
ENST00000601416.1
ZNF714
zinc finger protein 714
chr12_-_11150474 0.50 ENST00000538986.1
TAS2R20
taste receptor, type 2, member 20
chr6_-_134861089 0.49 ENST00000606039.1
RP11-557H15.4
RP11-557H15.4
chr17_-_41623716 0.48 ENST00000319349.5
ETV4
ets variant 4
chr10_+_70480963 0.48 ENST00000265872.6
ENST00000535016.1
ENST00000538031.1
ENST00000543719.1
ENST00000539539.1
ENST00000543225.1
ENST00000536012.1
ENST00000494903.2
CCAR1
cell division cycle and apoptosis regulator 1
chr8_+_32579341 0.47 ENST00000519240.1
ENST00000539990.1
NRG1
neuregulin 1
chr10_-_62493223 0.47 ENST00000373827.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr15_-_41166414 0.46 ENST00000220507.4
RHOV
ras homolog family member V
chr12_-_11287243 0.44 ENST00000539585.1
TAS2R30
taste receptor, type 2, member 30
chr11_+_6866883 0.44 ENST00000299454.4
ENST00000379831.2
OR10A5
olfactory receptor, family 10, subfamily A, member 5
chr11_-_89653576 0.44 ENST00000420869.1
TRIM49D1
tripartite motif containing 49D1
chr4_+_88754069 0.43 ENST00000395102.4
ENST00000497649.2
MEPE
matrix extracellular phosphoglycoprotein
chr4_+_88754113 0.43 ENST00000560249.1
ENST00000540395.1
ENST00000511670.1
ENST00000361056.3
MEPE
matrix extracellular phosphoglycoprotein
chr6_-_139613269 0.43 ENST00000358430.3
TXLNB
taxilin beta
chr17_-_79895154 0.43 ENST00000405481.4
ENST00000585215.1
ENST00000577624.1
ENST00000403172.4
PYCR1
pyrroline-5-carboxylate reductase 1
chr3_+_154797428 0.42 ENST00000460393.1
MME
membrane metallo-endopeptidase
chr14_+_96949319 0.42 ENST00000554706.1
AK7
adenylate kinase 7
chr7_+_134576317 0.41 ENST00000424922.1
ENST00000495522.1
CALD1
caldesmon 1
chr5_-_59481406 0.41 ENST00000546160.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr6_-_114194483 0.41 ENST00000434296.2
RP1-249H1.4
RP1-249H1.4
chr17_-_79895097 0.41 ENST00000402252.2
ENST00000583564.1
ENST00000585244.1
ENST00000337943.5
ENST00000579698.1
PYCR1
pyrroline-5-carboxylate reductase 1
chr14_+_94577074 0.41 ENST00000444961.1
ENST00000448882.1
ENST00000557098.1
ENST00000554800.1
ENST00000556544.1
ENST00000298902.5
ENST00000555819.1
ENST00000557634.1
ENST00000555744.1
IFI27
interferon, alpha-inducible protein 27
chrX_+_30261847 0.40 ENST00000378981.3
ENST00000397550.1
MAGEB1
melanoma antigen family B, 1
chr10_+_32873190 0.40 ENST00000375025.4
C10orf68
Homo sapiens coiled-coil domain containing 7 (CCDC7), transcript variant 5, mRNA.
chr3_+_171561127 0.40 ENST00000334567.5
ENST00000450693.1
TMEM212
transmembrane protein 212
chr15_+_67430339 0.40 ENST00000439724.3
SMAD3
SMAD family member 3
chr6_-_112408661 0.40 ENST00000368662.5
TUBE1
tubulin, epsilon 1
chr2_+_197577841 0.40 ENST00000409270.1
CCDC150
coiled-coil domain containing 150
chr7_-_41742697 0.40 ENST00000242208.4
INHBA
inhibin, beta A
chr13_-_41706864 0.39 ENST00000379485.1
ENST00000499385.2
KBTBD6
kelch repeat and BTB (POZ) domain containing 6
chr5_-_147211226 0.39 ENST00000296695.5
SPINK1
serine peptidase inhibitor, Kazal type 1
chrX_-_68385274 0.39 ENST00000374584.3
ENST00000590146.1
PJA1
praja ring finger 1, E3 ubiquitin protein ligase
chr6_-_161085291 0.39 ENST00000316300.5
LPA
lipoprotein, Lp(a)
chr5_-_173043591 0.39 ENST00000285908.5
ENST00000480951.1
ENST00000311086.4
BOD1
biorientation of chromosomes in cell division 1
chr3_+_98699880 0.39 ENST00000473756.1
LINC00973
long intergenic non-protein coding RNA 973
chr22_-_36236265 0.39 ENST00000414461.2
ENST00000416721.2
ENST00000449924.2
ENST00000262829.7
ENST00000397305.3
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chrX_-_68385354 0.39 ENST00000361478.1
PJA1
praja ring finger 1, E3 ubiquitin protein ligase
chr5_-_160279207 0.38 ENST00000327245.5
ATP10B
ATPase, class V, type 10B
chr10_-_61513146 0.38 ENST00000430431.1
LINC00948
long intergenic non-protein coding RNA 948
chr8_+_27631903 0.38 ENST00000305188.8
ESCO2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr2_-_69180012 0.38 ENST00000481498.1
GKN2
gastrokine 2
chr12_-_11184006 0.38 ENST00000390675.2
TAS2R31
taste receptor, type 2, member 31
chr12_-_11548496 0.38 ENST00000389362.4
ENST00000565533.1
ENST00000546254.1
PRB2
PRB1
proline-rich protein BstNI subfamily 2
proline-rich protein BstNI subfamily 1
chr6_-_44281043 0.38 ENST00000244571.4
AARS2
alanyl-tRNA synthetase 2, mitochondrial
chr2_+_166326157 0.37 ENST00000421875.1
ENST00000314499.7
ENST00000409664.1
CSRNP3
cysteine-serine-rich nuclear protein 3
chr9_+_4662282 0.37 ENST00000381883.2
PPAPDC2
phosphatidic acid phosphatase type 2 domain containing 2
chr1_-_205091115 0.37 ENST00000264515.6
ENST00000367164.1
RBBP5
retinoblastoma binding protein 5
chr4_+_146560245 0.36 ENST00000541599.1
MMAA
methylmalonic aciduria (cobalamin deficiency) cblA type
chr15_-_89089860 0.36 ENST00000558413.1
ENST00000564406.1
ENST00000268148.8
DET1
de-etiolated homolog 1 (Arabidopsis)
chrY_+_15016013 0.36 ENST00000360160.4
ENST00000454054.1
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr1_-_247921982 0.36 ENST00000408896.2
OR1C1
olfactory receptor, family 1, subfamily C, member 1
chr12_-_49393092 0.36 ENST00000421952.2
DDN
dendrin
chr12_+_97306295 0.35 ENST00000457368.2
NEDD1
neural precursor cell expressed, developmentally down-regulated 1
chr10_+_69865866 0.35 ENST00000354393.2
MYPN
myopalladin
chr5_-_75013193 0.35 ENST00000514838.2
ENST00000506164.1
ENST00000502826.1
ENST00000503835.1
ENST00000428202.2
ENST00000380475.2
POC5
POC5 centriolar protein
chr6_-_136847610 0.34 ENST00000454590.1
ENST00000432797.2
MAP7
microtubule-associated protein 7
chr19_+_21265028 0.34 ENST00000291770.7
ZNF714
zinc finger protein 714
chr1_-_36107445 0.34 ENST00000373237.3
PSMB2
proteasome (prosome, macropain) subunit, beta type, 2
chr2_+_58134756 0.34 ENST00000435505.2
ENST00000417641.2
VRK2
vaccinia related kinase 2
chr12_-_16758059 0.34 ENST00000261169.6
LMO3
LIM domain only 3 (rhombotin-like 2)
chr8_+_24151553 0.33 ENST00000265769.4
ENST00000540823.1
ENST00000397649.3
ADAM28
ADAM metallopeptidase domain 28
chr4_+_70894130 0.33 ENST00000526767.1
ENST00000530128.1
ENST00000381057.3
HTN3
histatin 3
chr18_-_57027194 0.33 ENST00000251047.5
LMAN1
lectin, mannose-binding, 1
chr12_-_10766184 0.33 ENST00000539554.1
ENST00000381881.2
ENST00000320756.2
MAGOHB
mago-nashi homolog B (Drosophila)
chr13_-_46716969 0.32 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr18_+_32173276 0.32 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
DTNA
dystrobrevin, alpha
chr19_-_36909528 0.32 ENST00000392161.3
ENST00000392171.1
ZFP82
ZFP82 zinc finger protein
chr5_+_140235469 0.32 ENST00000506939.2
ENST00000307360.5
PCDHA10
protocadherin alpha 10
chr12_-_10151773 0.32 ENST00000298527.6
ENST00000348658.4
CLEC1B
C-type lectin domain family 1, member B
chr16_-_20362147 0.31 ENST00000396142.2
UMOD
uromodulin
chr9_+_71394945 0.31 ENST00000394264.3
FAM122A
family with sequence similarity 122A
chr4_+_95128748 0.31 ENST00000359052.4
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr21_+_25801041 0.31 ENST00000453784.2
ENST00000423581.1
AP000476.1
AP000476.1
chr3_+_141594966 0.31 ENST00000475483.1
ATP1B3
ATPase, Na+/K+ transporting, beta 3 polypeptide
chr7_+_138145145 0.31 ENST00000415680.2
TRIM24
tripartite motif containing 24
chr2_+_168043793 0.30 ENST00000409273.1
ENST00000409605.1
XIRP2
xin actin-binding repeat containing 2
chr16_-_46782221 0.30 ENST00000394809.4
MYLK3
myosin light chain kinase 3
chr15_+_66679155 0.30 ENST00000307102.5
MAP2K1
mitogen-activated protein kinase kinase 1
chr4_-_73434498 0.30 ENST00000286657.4
ADAMTS3
ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr4_+_95128996 0.29 ENST00000457823.2
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr10_+_33271469 0.29 ENST00000414157.1
RP11-462L8.1
RP11-462L8.1
chr3_+_40518599 0.29 ENST00000314686.5
ENST00000447116.2
ENST00000429348.2
ENST00000456778.1
ZNF619
zinc finger protein 619
chr1_+_162039558 0.29 ENST00000530878.1
ENST00000361897.5
NOS1AP
nitric oxide synthase 1 (neuronal) adaptor protein
chr14_+_37126765 0.29 ENST00000402703.2
PAX9
paired box 9
chr2_-_11810284 0.29 ENST00000306928.5
NTSR2
neurotensin receptor 2
chr11_+_55578854 0.29 ENST00000333973.2
OR5L1
olfactory receptor, family 5, subfamily L, member 1
chr1_+_87012753 0.29 ENST00000370563.3
CLCA4
chloride channel accessory 4
chr22_+_24198890 0.29 ENST00000345044.6
SLC2A11
solute carrier family 2 (facilitated glucose transporter), member 11
chr4_-_83931862 0.29 ENST00000506560.1
ENST00000442461.2
ENST00000446851.2
ENST00000340417.3
LIN54
lin-54 homolog (C. elegans)
chr4_+_78804393 0.29 ENST00000502384.1
MRPL1
mitochondrial ribosomal protein L1
chr18_-_5419797 0.28 ENST00000542146.1
ENST00000427684.2
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr10_-_61513201 0.28 ENST00000414264.1
ENST00000594536.1
LINC00948
long intergenic non-protein coding RNA 948
chr11_-_102496063 0.28 ENST00000260228.2
MMP20
matrix metallopeptidase 20
chr11_+_124055923 0.28 ENST00000318666.6
OR10D3
olfactory receptor, family 10, subfamily D, member 3 (non-functional)
chr18_-_19997878 0.28 ENST00000391403.2
CTAGE1
cutaneous T-cell lymphoma-associated antigen 1
chr18_+_72201829 0.28 ENST00000582365.1
CNDP1
carnosine dipeptidase 1 (metallopeptidase M20 family)
chrX_-_109590174 0.27 ENST00000372054.1
GNG5P2
guanine nucleotide binding protein (G protein), gamma 5 pseudogene 2
chr7_-_131241361 0.27 ENST00000378555.3
ENST00000322985.9
ENST00000541194.1
ENST00000537928.1
PODXL
podocalyxin-like
chr12_-_11508520 0.27 ENST00000545626.1
ENST00000500254.2
PRB1
proline-rich protein BstNI subfamily 1
chr18_-_5540471 0.27 ENST00000581833.1
ENST00000544123.1
ENST00000342933.3
ENST00000400111.3
ENST00000585142.1
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr20_+_30555805 0.27 ENST00000562532.2
XKR7
XK, Kell blood group complex subunit-related family, member 7
chr9_+_116111794 0.27 ENST00000374183.4
BSPRY
B-box and SPRY domain containing
chr7_+_134576151 0.27 ENST00000393118.2
CALD1
caldesmon 1
chr2_+_187371440 0.27 ENST00000445547.1
ZC3H15
zinc finger CCCH-type containing 15
chr19_-_4535233 0.27 ENST00000381848.3
ENST00000588887.1
ENST00000586133.1
PLIN5
perilipin 5
chr4_-_56458374 0.27 ENST00000295645.4
PDCL2
phosducin-like 2
chr11_+_125496619 0.26 ENST00000532669.1
ENST00000278916.3
CHEK1
checkpoint kinase 1
chr1_-_115238207 0.26 ENST00000520113.2
ENST00000369538.3
ENST00000353928.6
AMPD1
adenosine monophosphate deaminase 1
chr1_-_162838551 0.26 ENST00000367910.1
ENST00000367912.2
ENST00000367911.2
C1orf110
chromosome 1 open reading frame 110
chr17_+_56232494 0.26 ENST00000268912.5
OR4D1
olfactory receptor, family 4, subfamily D, member 1
chr12_-_7596735 0.26 ENST00000416109.2
ENST00000396630.1
ENST00000313599.3
CD163L1
CD163 molecule-like 1
chr11_-_104827425 0.26 ENST00000393150.3
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr4_-_70518941 0.26 ENST00000286604.4
ENST00000505512.1
ENST00000514019.1
UGT2A1
UGT2A1
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
chr11_-_5345582 0.26 ENST00000328813.2
OR51B2
olfactory receptor, family 51, subfamily B, member 2
chr12_+_69202975 0.25 ENST00000544561.1
ENST00000393410.1
ENST00000299252.4
ENST00000360430.2
ENST00000517852.1
ENST00000545204.1
ENST00000393413.3
ENST00000350057.5
ENST00000348801.2
ENST00000478070.1
MDM2
MDM2 oncogene, E3 ubiquitin protein ligase
chr17_+_4692230 0.25 ENST00000331264.7
GLTPD2
glycolipid transfer protein domain containing 2
chr2_+_127066059 0.25 ENST00000435352.1
AC023347.1
AC023347.1
chr11_-_104817919 0.25 ENST00000533252.1
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr21_-_34186006 0.25 ENST00000490358.1
C21orf62
chromosome 21 open reading frame 62
chr8_+_118147498 0.24 ENST00000519688.1
ENST00000456015.2
SLC30A8
solute carrier family 30 (zinc transporter), member 8
chr11_+_125496124 0.24 ENST00000533778.2
ENST00000534070.1
CHEK1
checkpoint kinase 1
chr8_-_52721975 0.24 ENST00000356297.4
ENST00000543296.1
PXDNL
peroxidasin homolog (Drosophila)-like
chr15_-_89755034 0.24 ENST00000563254.1
RLBP1
retinaldehyde binding protein 1
chr4_+_95129061 0.24 ENST00000354268.4
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr2_-_151344172 0.23 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
RND3
Rho family GTPase 3
chr18_-_23671139 0.23 ENST00000579061.1
ENST00000542420.2
SS18
synovial sarcoma translocation, chromosome 18

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX13_SOX12

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.7 GO:0021564 vagus nerve development(GO:0021564)
0.4 1.6 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.4 1.6 GO:0055099 detection of endogenous stimulus(GO:0009726) response to high density lipoprotein particle(GO:0055099)
0.4 1.1 GO:0032289 central nervous system myelin formation(GO:0032289)
0.4 2.2 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.3 1.4 GO:0046035 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.3 0.9 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.2 2.9 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.2 1.1 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183)
0.2 3.1 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.2 1.3 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.2 1.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.2 0.5 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.1 0.4 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077) regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.1 0.9 GO:0044375 regulation of peroxisome size(GO:0044375)
0.1 0.4 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 0.8 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1 0.6 GO:0072023 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.1 1.1 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.8 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.1 0.6 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.1 0.5 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.3 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.1 0.9 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.3 GO:1903762 positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903762) positive regulation of ventricular cardiac muscle cell action potential(GO:1903947) positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905026) positive regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905033)
0.1 0.3 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.1 0.6 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.1 0.3 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 0.5 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 0.4 GO:0071492 creatinine metabolic process(GO:0046449) cellular response to UV-A(GO:0071492)
0.1 0.8 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 1.3 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 0.4 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.6 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.2 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.1 0.6 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 0.6 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 0.3 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 0.2 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.1 0.5 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 0.7 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1 0.5 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 0.2 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.1 0.4 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.9 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.1 0.3 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.1 0.4 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.1 0.8 GO:0070933 histone H4 deacetylation(GO:0070933)
0.1 0.2 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.1 1.7 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.1 0.7 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 0.3 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.1 0.3 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1 0.2 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.1 0.2 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.1 0.3 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.1 0.3 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.1 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.0 0.4 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.4 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.4 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.2 GO:1990523 response to vitamin K(GO:0032571) bone regeneration(GO:1990523)
0.0 0.8 GO:0008228 opsonization(GO:0008228)
0.0 0.4 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.2 GO:0009240 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
0.0 1.2 GO:0030728 ovulation(GO:0030728)
0.0 0.2 GO:0048749 compound eye development(GO:0048749)
0.0 0.3 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.2 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 1.1 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.1 GO:0035604 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604)
0.0 0.9 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.1 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.0 0.1 GO:1904833 positive regulation of superoxide dismutase activity(GO:1901671) positive regulation of removal of superoxide radicals(GO:1904833)
0.0 0.1 GO:2000097 chronological cell aging(GO:0001300) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0 0.2 GO:0003219 cardiac right ventricle formation(GO:0003219) visceral serous pericardium development(GO:0061032)
0.0 0.1 GO:0060988 lipid tube assembly(GO:0060988)
0.0 1.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.4 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.2 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.0 0.2 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.1 GO:0002740 negative regulation of cytokine secretion involved in immune response(GO:0002740)
0.0 0.3 GO:0042940 D-amino acid transport(GO:0042940)
0.0 0.2 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0 0.2 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.2 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 1.3 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.1 GO:1903899 positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.0 0.1 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.5 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 0.3 GO:0032264 IMP salvage(GO:0032264)
0.0 3.4 GO:0060337 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.1 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.0 0.1 GO:0019060 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 2.9 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.1 GO:0071048 nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
0.0 0.1 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.1 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.0 0.2 GO:0032119 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0 0.2 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.5 GO:0043383 negative T cell selection(GO:0043383)
0.0 0.2 GO:0003383 apical constriction(GO:0003383)
0.0 0.2 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.2 GO:0048478 replication fork protection(GO:0048478)
0.0 0.3 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.1 GO:0043474 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 0.5 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
0.0 0.1 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 2.5 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 1.5 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.1 GO:2001270 regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.2 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.2 GO:0009441 glycolate metabolic process(GO:0009441)
0.0 0.2 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.1 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.0 0.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.0 0.0 GO:0003162 atrioventricular node development(GO:0003162)
0.0 0.2 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.3 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.3 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.2 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.3 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.3 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.1 GO:0015811 L-alanine transport(GO:0015808) L-cystine transport(GO:0015811)
0.0 0.1 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.0 0.1 GO:0031296 positive regulation of germinal center formation(GO:0002636) B cell costimulation(GO:0031296)
0.0 0.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.4 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.1 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.1 GO:2000230 regulation of cholesterol transporter activity(GO:0060694) negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.0 0.1 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.0 0.1 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:0042737 drug catabolic process(GO:0042737)
0.0 0.1 GO:0072592 oxygen metabolic process(GO:0072592)
0.0 0.1 GO:0034983 peptidyl-lysine deacetylation(GO:0034983) negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0 0.0 GO:0097032 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 0.1 GO:1903438 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.2 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 1.2 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.2 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.4 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.1 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.1 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.4 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.4 GO:0030220 platelet formation(GO:0030220)
0.0 0.1 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.1 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0 0.1 GO:0001767 establishment of lymphocyte polarity(GO:0001767)
0.0 0.1 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.2 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.1 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.1 GO:0035803 egg coat formation(GO:0035803)
0.0 0.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.5 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.0 0.1 GO:0060437 lung growth(GO:0060437)
0.0 0.3 GO:0042481 regulation of odontogenesis(GO:0042481)
0.0 0.0 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.0 0.3 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.8 GO:0070206 protein trimerization(GO:0070206)
0.0 0.0 GO:0036215 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.0 0.2 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.0 0.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.0 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 2.0 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.0 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.0 GO:0021997 neural plate axis specification(GO:0021997)
0.0 0.2 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.3 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.4 GO:2000772 regulation of cellular senescence(GO:2000772)
0.0 0.4 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.5 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 0.1 GO:0048311 mitochondrion distribution(GO:0048311)
0.0 0.2 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.2 4.7 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.7 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 0.4 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 0.4 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1 0.9 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.1 0.6 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 0.8 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 0.3 GO:0030891 VCB complex(GO:0030891)
0.1 0.2 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.1 0.3 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 0.8 GO:0030478 actin cap(GO:0030478)
0.1 0.6 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 0.4 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.1 GO:0044609 DBIRD complex(GO:0044609)
0.0 0.4 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 1.5 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.1 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.0 0.3 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.9 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.2 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.4 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 1.2 GO:0030673 axolemma(GO:0030673)
0.0 0.2 GO:1990037 Lewy body core(GO:1990037)
0.0 0.8 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.2 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.3 GO:0016342 catenin complex(GO:0016342)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 1.1 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.3 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.0 0.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.1 GO:0071020 post-spliceosomal complex(GO:0071020)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 6.5 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.2 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.1 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.0 0.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.3 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.2 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 1.4 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.1 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.1 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.1 GO:0070938 contractile ring(GO:0070938)
0.0 0.0 GO:0033150 cytoskeletal calyx(GO:0033150)
0.0 0.2 GO:0032433 filopodium tip(GO:0032433)
0.0 0.1 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.8 GO:0015030 Cajal body(GO:0015030)
0.0 0.1 GO:0016013 syntrophin complex(GO:0016013)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0002113 interleukin-33 binding(GO:0002113)
0.5 1.6 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.4 1.3 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.2 0.9 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.2 1.6 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.2 0.5 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.1 0.9 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.8 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 0.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 2.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.4 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 1.4 GO:0004849 uridine kinase activity(GO:0004849)
0.1 1.7 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.9 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.9 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.6 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 0.4 GO:0004127 cytidylate kinase activity(GO:0004127)
0.1 0.9 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.4 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.2 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.4 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.7 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.1 0.7 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 0.2 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.1 0.2 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.1 0.2 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.1 1.2 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 0.4 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 0.2 GO:0047223 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
0.1 0.6 GO:0034056 estrogen response element binding(GO:0034056)
0.1 0.2 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.1 0.3 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.2 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.0 0.5 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 1.0 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.3 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.4 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.3 GO:0035473 lipase binding(GO:0035473)
0.0 1.5 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 1.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0004074 biliverdin reductase activity(GO:0004074)
0.0 0.6 GO:0019864 IgG binding(GO:0019864)
0.0 0.8 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.2 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.9 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.3 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 1.3 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.2 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.1 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.0 0.3 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.2 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.0 0.2 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.8 GO:0005523 tropomyosin binding(GO:0005523)
0.0 3.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.5 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.6 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.1 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.0 2.5 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.2 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.1 GO:0031768 ghrelin receptor binding(GO:0031768)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.2 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 4.9 GO:0004386 helicase activity(GO:0004386)
0.0 0.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0098625 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.0 0.3 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.1 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) L-cystine transmembrane transporter activity(GO:0015184) alanine transmembrane transporter activity(GO:0022858)
0.0 0.2 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.1 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948)
0.0 0.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.1 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.2 GO:0089720 caspase binding(GO:0089720)
0.0 0.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.3 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.2 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.2 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.3 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.2 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.2 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.3 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.9 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.1 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.2 GO:0004697 protein kinase C activity(GO:0004697)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.8 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.1 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.4 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.0 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.6 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.6 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.2 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.9 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.6 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.2 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.7 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.5 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.2 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.1 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.6 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.8 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.4 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.2 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.3 PID TCPTP PATHWAY Signaling events mediated by TCPTP

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.2 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.1 1.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.8 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 3.3 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.7 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 1.4 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 1.5 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 1.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.7 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.3 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 2.3 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.4 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.4 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.0 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.4 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.4 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.4 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.3 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.5 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 1.4 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.3 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 1.0 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.4 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.3 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.1 REACTOME OPSINS Genes involved in Opsins