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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for SOX17

Z-value: 0.80

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Transcription factors associated with SOX17

Gene Symbol Gene ID Gene Info
SOX17
ENSG00000164736.5 SRY-box transcription factor 17

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX17hg19_v2_chr8_+_55370487_553705030.377.1e-02Click!

Activity profile of SOX17 motif

Sorted Z-values of SOX17 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_41158742 3.62 ENST00000415816.2
ENST00000438323.2
IFI35
interferon-induced protein 35
chr4_-_74864386 2.37 ENST00000296027.4
CXCL5
chemokine (C-X-C motif) ligand 5
chr20_-_62199427 2.01 ENST00000427522.2
HELZ2
helicase with zinc finger 2, transcriptional coactivator
chr11_-_102668879 1.89 ENST00000315274.6
MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr2_+_103035102 1.30 ENST00000264260.2
IL18RAP
interleukin 18 receptor accessory protein
chr5_-_146833485 1.27 ENST00000398514.3
DPYSL3
dihydropyrimidinase-like 3
chr1_+_205225319 1.26 ENST00000329800.7
TMCC2
transmembrane and coiled-coil domain family 2
chr12_+_9822331 1.23 ENST00000545918.1
ENST00000543300.1
ENST00000261339.6
ENST00000466035.2
CLEC2D
C-type lectin domain family 2, member D
chr8_+_104383728 1.14 ENST00000330295.5
CTHRC1
collagen triple helix repeat containing 1
chr2_-_11810284 1.07 ENST00000306928.5
NTSR2
neurotensin receptor 2
chr16_+_33629600 1.02 ENST00000562905.2
IGHV3OR16-13
immunoglobulin heavy variable 3/OR16-13 (non-functional)
chr1_+_87012753 0.99 ENST00000370563.3
CLCA4
chloride channel accessory 4
chr11_-_108464465 0.94 ENST00000525344.1
EXPH5
exophilin 5
chr6_+_126240442 0.94 ENST00000448104.1
ENST00000438495.1
ENST00000444128.1
NCOA7
nuclear receptor coactivator 7
chr14_+_94577074 0.93 ENST00000444961.1
ENST00000448882.1
ENST00000557098.1
ENST00000554800.1
ENST00000556544.1
ENST00000298902.5
ENST00000555819.1
ENST00000557634.1
ENST00000555744.1
IFI27
interferon, alpha-inducible protein 27
chr17_+_41132564 0.89 ENST00000361677.1
ENST00000589705.1
RUNDC1
RUN domain containing 1
chr14_-_55369525 0.87 ENST00000543643.2
ENST00000536224.2
ENST00000395514.1
ENST00000491895.2
GCH1
GTP cyclohydrolase 1
chr4_+_100495864 0.86 ENST00000265517.5
ENST00000422897.2
MTTP
microsomal triglyceride transfer protein
chrX_+_49216659 0.86 ENST00000415752.1
GAGE12I
G antigen 12I
chr11_-_7695437 0.86 ENST00000533558.1
ENST00000527542.1
ENST00000531096.1
CYB5R2
cytochrome b5 reductase 2
chr2_-_231090344 0.84 ENST00000540870.1
ENST00000416610.1
SP110
SP110 nuclear body protein
chr5_-_146833222 0.81 ENST00000534907.1
DPYSL3
dihydropyrimidinase-like 3
chr4_-_122085469 0.78 ENST00000057513.3
TNIP3
TNFAIP3 interacting protein 3
chr11_-_35440579 0.78 ENST00000606205.1
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr7_-_115608304 0.77 ENST00000457268.1
TFEC
transcription factor EC
chr6_-_31239846 0.74 ENST00000415537.1
ENST00000376228.5
ENST00000383329.3
HLA-C
major histocompatibility complex, class I, C
chr10_+_6622345 0.73 ENST00000445427.1
ENST00000455810.1
PRKCQ-AS1
PRKCQ antisense RNA 1
chr14_+_21525981 0.73 ENST00000308227.2
RNASE8
ribonuclease, RNase A family, 8
chr12_-_11150474 0.71 ENST00000538986.1
TAS2R20
taste receptor, type 2, member 20
chr1_-_31661000 0.69 ENST00000263693.1
ENST00000398657.2
ENST00000526106.1
NKAIN1
Na+/K+ transporting ATPase interacting 1
chr6_-_52710893 0.69 ENST00000284562.2
GSTA5
glutathione S-transferase alpha 5
chr3_+_46412345 0.69 ENST00000292303.4
CCR5
chemokine (C-C motif) receptor 5 (gene/pseudogene)
chr9_+_100174232 0.68 ENST00000355295.4
TDRD7
tudor domain containing 7
chr5_+_49962772 0.67 ENST00000281631.5
ENST00000513738.1
ENST00000503665.1
ENST00000514067.2
ENST00000503046.1
PARP8
poly (ADP-ribose) polymerase family, member 8
chr17_-_55822653 0.66 ENST00000299415.2
AC007431.1
coiled-coil domain containing 182
chr11_+_6226782 0.65 ENST00000316375.2
C11orf42
chromosome 11 open reading frame 42
chr1_-_6662919 0.63 ENST00000377658.4
ENST00000377663.3
KLHL21
kelch-like family member 21
chr1_+_107682629 0.63 ENST00000370074.4
ENST00000370073.2
ENST00000370071.2
ENST00000542803.1
ENST00000370061.3
ENST00000370072.3
ENST00000370070.2
NTNG1
netrin G1
chr2_+_102928009 0.62 ENST00000404917.2
ENST00000447231.1
IL1RL1
interleukin 1 receptor-like 1
chr1_-_205091115 0.62 ENST00000264515.6
ENST00000367164.1
RBBP5
retinoblastoma binding protein 5
chr11_-_102496063 0.61 ENST00000260228.2
MMP20
matrix metallopeptidase 20
chr19_-_47735918 0.60 ENST00000449228.1
ENST00000300880.7
ENST00000341983.4
BBC3
BCL2 binding component 3
chr6_+_31916733 0.60 ENST00000483004.1
CFB
complement factor B
chr2_-_89399845 0.59 ENST00000479981.1
IGKV1-16
immunoglobulin kappa variable 1-16
chr15_-_89755034 0.55 ENST00000563254.1
RLBP1
retinaldehyde binding protein 1
chr16_+_29467780 0.53 ENST00000395400.3
SULT1A4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
chr11_+_60163775 0.52 ENST00000300187.6
ENST00000395005.2
MS4A14
membrane-spanning 4-domains, subfamily A, member 14
chr5_+_98109322 0.52 ENST00000513185.1
RGMB
repulsive guidance molecule family member b
chr18_-_19748331 0.51 ENST00000584201.1
GATA6-AS1
GATA6 antisense RNA 1 (head to head)
chr19_+_10764937 0.50 ENST00000449870.1
ENST00000318511.3
ENST00000420083.1
ILF3
interleukin enhancer binding factor 3, 90kDa
chr22_-_24951054 0.50 ENST00000447813.2
ENST00000402766.1
ENST00000407471.3
ENST00000435822.1
GUCD1
guanylyl cyclase domain containing 1
chr5_+_125758865 0.49 ENST00000542322.1
ENST00000544396.1
GRAMD3
GRAM domain containing 3
chr6_-_52628271 0.48 ENST00000493422.1
GSTA2
glutathione S-transferase alpha 2
chr22_-_32651326 0.48 ENST00000266086.4
SLC5A4
solute carrier family 5 (glucose activated ion channel), member 4
chr15_+_34310428 0.48 ENST00000557872.1
CHRM5
cholinergic receptor, muscarinic 5
chr6_+_126277842 0.47 ENST00000229633.5
HINT3
histidine triad nucleotide binding protein 3
chr15_+_93749295 0.47 ENST00000599897.1
AC112693.2
AC112693.2
chr5_+_125758813 0.46 ENST00000285689.3
ENST00000515200.1
GRAMD3
GRAM domain containing 3
chr4_-_56458374 0.46 ENST00000295645.4
PDCL2
phosducin-like 2
chr7_+_100551239 0.46 ENST00000319509.7
MUC3A
mucin 3A, cell surface associated
chr8_+_110098850 0.45 ENST00000518632.1
TRHR
thyrotropin-releasing hormone receptor
chr5_+_167913450 0.45 ENST00000231572.3
ENST00000538719.1
RARS
arginyl-tRNA synthetase
chr17_-_2966901 0.45 ENST00000575751.1
OR1D5
olfactory receptor, family 1, subfamily D, member 5
chr5_-_41213607 0.45 ENST00000337836.5
ENST00000433294.1
C6
complement component 6
chr11_+_60163918 0.44 ENST00000526375.1
ENST00000531783.1
ENST00000395001.1
MS4A14
membrane-spanning 4-domains, subfamily A, member 14
chr12_-_323689 0.44 ENST00000428720.1
SLC6A12
solute carrier family 6 (neurotransmitter transporter), member 12
chr15_-_65117807 0.44 ENST00000559239.1
ENST00000268043.4
ENST00000333425.6
PIF1
PIF1 5'-to-3' DNA helicase
chrX_+_49363665 0.44 ENST00000381700.6
GAGE1
G antigen 1
chr20_-_1309809 0.44 ENST00000360779.3
SDCBP2
syndecan binding protein (syntenin) 2
chr5_+_81601166 0.43 ENST00000439350.1
ATP6AP1L
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr11_-_123756334 0.43 ENST00000528595.1
ENST00000375026.2
TMEM225
transmembrane protein 225
chr3_+_111260856 0.42 ENST00000352690.4
CD96
CD96 molecule
chr1_-_145075847 0.42 ENST00000530740.1
ENST00000369359.4
PDE4DIP
phosphodiesterase 4D interacting protein
chr12_-_8815215 0.41 ENST00000544889.1
ENST00000543369.1
MFAP5
microfibrillar associated protein 5
chr17_+_56232494 0.41 ENST00000268912.5
OR4D1
olfactory receptor, family 4, subfamily D, member 1
chr2_+_71357434 0.41 ENST00000244230.2
MPHOSPH10
M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
chr11_-_104817919 0.40 ENST00000533252.1
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr20_+_61448376 0.40 ENST00000343916.3
COL9A3
collagen, type IX, alpha 3
chr1_-_198990166 0.40 ENST00000427439.1
RP11-16L9.3
RP11-16L9.3
chrX_+_140982452 0.40 ENST00000544766.1
MAGEC3
melanoma antigen family C, 3
chr11_+_55653396 0.40 ENST00000244891.3
TRIM51
tripartite motif-containing 51
chr2_-_89417335 0.40 ENST00000490686.1
IGKV1-17
immunoglobulin kappa variable 1-17
chr3_-_139195350 0.40 ENST00000232217.2
RBP2
retinol binding protein 2, cellular
chr1_+_174417095 0.39 ENST00000367685.2
GPR52
G protein-coupled receptor 52
chr6_-_52705641 0.39 ENST00000370989.2
GSTA5
glutathione S-transferase alpha 5
chr17_-_30228678 0.38 ENST00000261708.4
UTP6
UTP6, small subunit (SSU) processome component, homolog (yeast)
chr10_-_115614127 0.38 ENST00000369305.1
DCLRE1A
DNA cross-link repair 1A
chr10_-_95209 0.38 ENST00000332708.5
ENST00000309812.4
TUBB8
tubulin, beta 8 class VIII
chr9_+_139717847 0.38 ENST00000436380.1
RABL6
RAB, member RAS oncogene family-like 6
chr17_-_39324424 0.38 ENST00000391356.2
KRTAP4-3
keratin associated protein 4-3
chr2_+_102413726 0.37 ENST00000350878.4
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr3_-_147124547 0.37 ENST00000491672.1
ENST00000383075.3
ZIC4
Zic family member 4
chr17_-_64225508 0.36 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr2_-_118943930 0.36 ENST00000449075.1
ENST00000414886.1
ENST00000449819.1
AC093901.1
AC093901.1
chr3_+_174577070 0.36 ENST00000454872.1
NAALADL2
N-acetylated alpha-linked acidic dipeptidase-like 2
chr3_+_88108381 0.35 ENST00000473136.1
RP11-159G9.5
Uncharacterized protein
chr17_-_4852243 0.35 ENST00000225655.5
PFN1
profilin 1
chr1_+_84873913 0.35 ENST00000370662.3
DNASE2B
deoxyribonuclease II beta
chr19_+_10765003 0.34 ENST00000407004.3
ENST00000589998.1
ENST00000589600.1
ILF3
interleukin enhancer binding factor 3, 90kDa
chr19_+_49956426 0.34 ENST00000293350.4
ENST00000540132.1
ENST00000455361.2
ENST00000433981.2
ALDH16A1
aldehyde dehydrogenase 16 family, member A1
chr7_-_121944491 0.33 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1
FEZ family zinc finger 1
chr18_+_21572737 0.33 ENST00000304621.6
TTC39C
tetratricopeptide repeat domain 39C
chr2_+_233527443 0.33 ENST00000410095.1
EFHD1
EF-hand domain family, member D1
chrX_+_49235708 0.33 ENST00000381725.1
GAGE2B
G antigen 2B
chr2_-_71222466 0.33 ENST00000606025.1
AC007040.11
Uncharacterized protein
chr6_+_29910301 0.32 ENST00000376809.5
ENST00000376802.2
HLA-A
major histocompatibility complex, class I, A
chr11_+_5372738 0.32 ENST00000380219.1
OR51B6
olfactory receptor, family 51, subfamily B, member 6
chrX_-_6453159 0.31 ENST00000381089.3
ENST00000398729.1
VCX3A
variable charge, X-linked 3A
chr6_+_159071015 0.31 ENST00000360448.3
SYTL3
synaptotagmin-like 3
chr13_-_39564993 0.31 ENST00000423210.1
STOML3
stomatin (EPB72)-like 3
chr2_-_190044480 0.31 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr2_-_100939195 0.31 ENST00000393437.3
LONRF2
LON peptidase N-terminal domain and ring finger 2
chr3_-_11610255 0.31 ENST00000424529.2
VGLL4
vestigial like 4 (Drosophila)
chr12_-_11463353 0.30 ENST00000279575.1
ENST00000535904.1
ENST00000445719.2
PRB4
proline-rich protein BstNI subfamily 4
chr3_-_48481434 0.30 ENST00000395694.2
ENST00000447018.1
ENST00000442740.1
CCDC51
coiled-coil domain containing 51
chr1_+_47137544 0.30 ENST00000564373.1
TEX38
testis expressed 38
chr1_-_13005246 0.29 ENST00000415464.2
PRAMEF6
PRAME family member 6
chr8_+_110099653 0.29 ENST00000311762.2
TRHR
thyrotropin-releasing hormone receptor
chr15_-_81202118 0.29 ENST00000560560.1
RP11-351M8.1
Uncharacterized protein
chrX_-_109590174 0.29 ENST00000372054.1
GNG5P2
guanine nucleotide binding protein (G protein), gamma 5 pseudogene 2
chr19_+_58095501 0.29 ENST00000536878.2
ENST00000597850.1
ENST00000597219.1
ENST00000598689.1
ENST00000599456.1
ENST00000307468.4
ZIK1
zinc finger protein interacting with K protein 1
chr15_-_76304731 0.29 ENST00000394907.3
NRG4
neuregulin 4
chr1_-_160492994 0.29 ENST00000368055.1
ENST00000368057.3
ENST00000368059.3
SLAMF6
SLAM family member 6
chr12_-_11244912 0.28 ENST00000531678.1
TAS2R43
taste receptor, type 2, member 43
chr6_+_10556215 0.28 ENST00000316170.3
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr2_-_74735707 0.28 ENST00000233630.6
PCGF1
polycomb group ring finger 1
chr3_+_111260954 0.28 ENST00000283285.5
CD96
CD96 molecule
chr11_+_60145997 0.28 ENST00000530614.1
ENST00000530027.1
ENST00000530234.2
ENST00000528215.1
ENST00000531787.1
MS4A7
MS4A14
membrane-spanning 4-domains, subfamily A, member 7
membrane-spanning 4-domains, subfamily A, member 14
chr4_-_76008706 0.28 ENST00000562355.1
ENST00000563602.1
RP11-44F21.5
RP11-44F21.5
chr19_-_58514129 0.28 ENST00000552184.1
ENST00000546715.1
ENST00000536132.1
ENST00000547828.1
ENST00000547121.1
ENST00000551380.1
ZNF606
zinc finger protein 606
chr18_-_19748379 0.28 ENST00000579431.1
GATA6-AS1
GATA6 antisense RNA 1 (head to head)
chr1_+_13641973 0.28 ENST00000330087.5
PRAMEF15
PRAME family member 15
chr19_+_6135646 0.28 ENST00000588304.1
ENST00000588485.1
ENST00000588722.1
ENST00000591403.1
ENST00000586696.1
ENST00000589401.1
ENST00000252669.5
ACSBG2
acyl-CoA synthetase bubblegum family member 2
chr7_-_22234381 0.27 ENST00000458533.1
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr18_+_616672 0.27 ENST00000338387.7
CLUL1
clusterin-like 1 (retinal)
chrX_-_13338518 0.27 ENST00000380622.2
ATXN3L
ataxin 3-like
chr4_-_100065440 0.27 ENST00000508393.1
ENST00000265512.7
ADH4
alcohol dehydrogenase 4 (class II), pi polypeptide
chr6_-_42690312 0.27 ENST00000230381.5
PRPH2
peripherin 2 (retinal degeneration, slow)
chrX_+_8432871 0.27 ENST00000381032.1
ENST00000453306.1
ENST00000444481.1
VCX3B
variable charge, X-linked 3B
chr11_+_60145948 0.27 ENST00000300184.3
ENST00000358246.1
MS4A7
membrane-spanning 4-domains, subfamily A, member 7
chr8_+_27631903 0.27 ENST00000305188.8
ESCO2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr22_-_32589466 0.27 ENST00000248980.4
RFPL2
ret finger protein-like 2
chr3_+_111260980 0.27 ENST00000438817.2
CD96
CD96 molecule
chr10_-_127371675 0.27 ENST00000532135.1
ENST00000526819.1
ENST00000368821.3
TEX36
testis expressed 36
chr17_+_27181956 0.27 ENST00000254928.5
ENST00000580917.2
ERAL1
Era-like 12S mitochondrial rRNA chaperone 1
chr6_+_167704838 0.26 ENST00000366829.2
UNC93A
unc-93 homolog A (C. elegans)
chr19_-_21776784 0.26 ENST00000594927.1
RP11-678G14.4
RP11-678G14.4
chr22_+_44464923 0.26 ENST00000404989.1
PARVB
parvin, beta
chr3_-_48481518 0.26 ENST00000412398.2
ENST00000395696.1
CCDC51
coiled-coil domain containing 51
chr3_-_45837959 0.26 ENST00000353278.4
ENST00000456124.2
SLC6A20
solute carrier family 6 (proline IMINO transporter), member 20
chr1_+_197382957 0.26 ENST00000367397.1
CRB1
crumbs homolog 1 (Drosophila)
chr12_+_70219052 0.26 ENST00000552032.2
ENST00000547771.2
MYRFL
myelin regulatory factor-like
chr3_-_45838011 0.26 ENST00000358525.4
ENST00000413781.1
SLC6A20
solute carrier family 6 (proline IMINO transporter), member 20
chr3_+_185304059 0.26 ENST00000427465.2
SENP2
SUMO1/sentrin/SMT3 specific peptidase 2
chr6_+_167704798 0.26 ENST00000230256.3
UNC93A
unc-93 homolog A (C. elegans)
chr17_-_4852332 0.25 ENST00000572383.1
PFN1
profilin 1
chr11_+_60145967 0.25 ENST00000534016.1
MS4A7
membrane-spanning 4-domains, subfamily A, member 7
chr1_+_171283331 0.25 ENST00000367749.3
FMO4
flavin containing monooxygenase 4
chr8_+_21155717 0.25 ENST00000522755.1
ENST00000519996.1
RP11-24P4.1
RP11-24P4.1
chr22_+_27053190 0.25 ENST00000439738.1
ENST00000422403.1
ENST00000436238.1
ENST00000425476.1
ENST00000455640.1
ENST00000451141.1
ENST00000452429.1
ENST00000423278.1
MIAT
myocardial infarction associated transcript (non-protein coding)
chr12_-_498620 0.25 ENST00000399788.2
ENST00000382815.4
KDM5A
lysine (K)-specific demethylase 5A
chr1_+_45805342 0.24 ENST00000372090.5
TOE1
target of EGR1, member 1 (nuclear)
chr3_+_185303962 0.24 ENST00000296257.5
SENP2
SUMO1/sentrin/SMT3 specific peptidase 2
chr15_+_101459420 0.24 ENST00000388948.3
ENST00000284395.5
ENST00000534045.1
ENST00000532029.2
LRRK1
leucine-rich repeat kinase 1
chr18_+_22040620 0.24 ENST00000426880.2
HRH4
histamine receptor H4
chr2_+_239335449 0.24 ENST00000264607.4
ASB1
ankyrin repeat and SOCS box containing 1
chr22_+_41075277 0.24 ENST00000381433.2
MCHR1
melanin-concentrating hormone receptor 1
chr12_-_111358372 0.23 ENST00000548438.1
ENST00000228841.8
MYL2
myosin, light chain 2, regulatory, cardiac, slow
chr12_-_7596735 0.23 ENST00000416109.2
ENST00000396630.1
ENST00000313599.3
CD163L1
CD163 molecule-like 1
chr7_-_29186008 0.23 ENST00000396276.3
ENST00000265394.5
CPVL
carboxypeptidase, vitellogenic-like
chr17_-_2169425 0.23 ENST00000570606.1
ENST00000354901.4
SMG6
SMG6 nonsense mediated mRNA decay factor
chr11_-_89654935 0.23 ENST00000530311.2
TRIM49D1
tripartite motif containing 49D1
chr1_+_13359819 0.23 ENST00000376168.1
PRAMEF5
PRAME family member 5
chr5_+_112196919 0.23 ENST00000505459.1
ENST00000282999.3
ENST00000515463.1
SRP19
signal recognition particle 19kDa
chr1_+_47137445 0.23 ENST00000569393.1
ENST00000334122.4
ENST00000415500.1
TEX38
testis expressed 38
chr8_-_52721975 0.23 ENST00000356297.4
ENST00000543296.1
PXDNL
peroxidasin homolog (Drosophila)-like
chr12_-_8815299 0.22 ENST00000535336.1
MFAP5
microfibrillar associated protein 5
chr19_+_34895289 0.22 ENST00000246535.3
PDCD2L
programmed cell death 2-like
chr13_-_24895566 0.22 ENST00000422229.2
AL359736.1
protein PCOTH isoform 1
chr19_+_3933579 0.22 ENST00000593949.1
NMRK2
nicotinamide riboside kinase 2
chr1_+_207669613 0.21 ENST00000367049.4
ENST00000529814.1
CR1
complement component (3b/4b) receptor 1 (Knops blood group)
chr1_-_12946025 0.21 ENST00000235349.5
PRAMEF4
PRAME family member 4
chr1_+_45805728 0.21 ENST00000539779.1
TOE1
target of EGR1, member 1 (nuclear)
chr4_+_128554081 0.21 ENST00000335251.6
ENST00000296461.5
INTU
inturned planar cell polarity protein
chrX_-_103268259 0.21 ENST00000217926.5
H2BFWT
H2B histone family, member W, testis-specific
chr11_+_125365110 0.21 ENST00000527818.1
AP000708.1
AP000708.1
chr19_-_49956728 0.21 ENST00000601825.1
ENST00000596049.1
ENST00000599366.1
ENST00000597415.1
PIH1D1
PIH1 domain containing 1
chr4_-_168155577 0.21 ENST00000541354.1
ENST00000509854.1
ENST00000512681.1
ENST00000421836.2
ENST00000510741.1
ENST00000510403.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr3_-_167371740 0.20 ENST00000466760.1
ENST00000479765.1
WDR49
WD repeat domain 49
chr1_+_22333943 0.20 ENST00000400271.2
CELA3A
chymotrypsin-like elastase family, member 3A
chr10_+_18549645 0.20 ENST00000396576.2
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr1_-_13007420 0.20 ENST00000376189.1
PRAMEF6
PRAME family member 6
chr18_+_22040593 0.20 ENST00000256906.4
HRH4
histamine receptor H4
chr11_+_4788500 0.20 ENST00000380390.1
MMP26
matrix metallopeptidase 26
chr17_-_67264947 0.20 ENST00000586811.1
ABCA5
ATP-binding cassette, sub-family A (ABC1), member 5
chr2_+_89184868 0.20 ENST00000390243.2
IGKV4-1
immunoglobulin kappa variable 4-1
chr6_-_119031228 0.20 ENST00000392500.3
ENST00000368488.5
ENST00000434604.1
CEP85L
centrosomal protein 85kDa-like
chr17_+_57297807 0.20 ENST00000284116.4
ENST00000581140.1
ENST00000581276.1
GDPD1
glycerophosphodiester phosphodiesterase domain containing 1
chr2_+_187371440 0.20 ENST00000445547.1
ZC3H15
zinc finger CCCH-type containing 15
chr20_-_23860373 0.19 ENST00000304710.4
CST5
cystatin D

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX17

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.3 0.9 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.2 0.6 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.2 1.1 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.1 0.4 GO:0030451 regulation of complement activation, alternative pathway(GO:0030451) negative regulation of complement activation, alternative pathway(GO:0045957)
0.1 0.7 GO:0061760 antifungal innate immune response(GO:0061760)
0.1 0.4 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.1 1.1 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.1 0.3 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 1.2 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1 0.7 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.1 0.8 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 0.5 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1 2.1 GO:0051764 actin crosslink formation(GO:0051764)
0.1 2.4 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.1 0.4 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
0.1 0.2 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.1 0.5 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 0.4 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.1 0.4 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.1 0.2 GO:1903939 negative regulation of histone H3-K9 dimethylation(GO:1900110) regulation of TORC2 signaling(GO:1903939)
0.1 0.5 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.1 0.2 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.1 0.9 GO:0006776 vitamin A metabolic process(GO:0006776)
0.1 0.2 GO:0032826 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.1 0.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.6 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.1 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.9 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 1.9 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.0 0.3 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.1 GO:0018874 benzoate metabolic process(GO:0018874)
0.0 0.5 GO:0015824 proline transport(GO:0015824)
0.0 0.5 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.3 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.1 GO:0010949 negative regulation of intestinal phytosterol absorption(GO:0010949) negative regulation of intestinal cholesterol absorption(GO:0045796) intestinal phytosterol absorption(GO:0060752) negative regulation of intestinal lipid absorption(GO:1904730)
0.0 0.9 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.4 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.1 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0 0.3 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 4.1 GO:0060337 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.1 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.0 0.2 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.1 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.2 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.1 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.6 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.0 0.3 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.0 0.2 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.0 0.2 GO:0045007 depurination(GO:0045007)
0.0 0.1 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.0 0.4 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.1 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.0 0.2 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.0 0.1 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.2 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.0 0.4 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.4 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.1 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.0 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.0 0.7 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.1 GO:1902714 antifungal humoral response(GO:0019732) negative regulation of interferon-gamma secretion(GO:1902714)
0.0 0.9 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.3 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.3 GO:0042737 drug catabolic process(GO:0042737)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.3 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.5 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 1.3 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.0 0.6 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.3 GO:0001787 natural killer cell proliferation(GO:0001787)
0.0 0.8 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.0 1.0 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.1 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
0.0 0.2 GO:0070525 tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.0 0.5 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.5 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.2 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:1990502 dense core granule maturation(GO:1990502)
0.0 0.9 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.6 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.0 0.8 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 1.4 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.1 GO:0032962 positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.2 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0 0.1 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 0.1 GO:0002097 tRNA wobble base modification(GO:0002097)
0.0 1.3 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.1 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 0.6 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.3 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.4 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.1 GO:0070508 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.0 0.0 GO:0016098 monoterpenoid metabolic process(GO:0016098)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0034457 Mpp10 complex(GO:0034457)
0.1 0.3 GO:0005588 collagen type V trimer(GO:0005588)
0.1 1.1 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.7 GO:0005827 polar microtubule(GO:0005827)
0.1 0.4 GO:0005594 collagen type IX trimer(GO:0005594)
0.1 0.4 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 0.2 GO:0097058 CRLF-CLCF1 complex(GO:0097058) CNTFR-CLCF1 complex(GO:0097059)
0.1 0.2 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.4 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.4 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.1 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.7 GO:0033391 chromatoid body(GO:0033391)
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.4 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.1 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.4 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.3 GO:0000801 central element(GO:0000801)
0.0 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.2 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 1.5 GO:0031941 filamentous actin(GO:0031941)
0.0 0.0 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 1.1 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.5 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.4 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.9 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.8 GO:0030673 axolemma(GO:0030673)
0.0 0.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.0 0.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.2 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.2 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.1 GO:0000124 SAGA complex(GO:0000124)
0.0 0.9 GO:0005637 nuclear inner membrane(GO:0005637)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.1 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 0.4 GO:0002113 interleukin-33 binding(GO:0002113)
0.1 2.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.4 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) DNA/RNA helicase activity(GO:0033677)
0.1 0.4 GO:0001861 complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877)
0.1 0.3 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.1 0.8 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.7 GO:0004522 ribonuclease A activity(GO:0004522)
0.1 0.4 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.1 0.9 GO:0019238 cyclohydrolase activity(GO:0019238)
0.1 0.2 GO:0005503 all-trans retinal binding(GO:0005503)
0.1 0.5 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 0.5 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 0.5 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 0.5 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.1 0.5 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 0.7 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 0.4 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.5 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 0.2 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.1 0.7 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 0.7 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 0.4 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.6 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.2 GO:0032406 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.0 0.4 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.4 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.2 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 0.6 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.2 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.3 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.1 GO:0098625 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.0 0.3 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 3.1 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.4 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.9 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 1.0 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 1.0 GO:0005521 lamin binding(GO:0005521)
0.0 0.3 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0030614 oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
0.0 1.4 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.2 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 1.1 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.1 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.0 0.5 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.4 GO:0016918 retinal binding(GO:0016918)
0.0 0.6 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.2 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.5 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 1.2 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 2.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.1 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.3 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.2 GO:0008312 7S RNA binding(GO:0008312)
0.0 0.3 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.1 GO:0019960 C-X3-C chemokine binding(GO:0019960) protein antigen binding(GO:1990405)
0.0 0.6 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.9 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.3 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.0 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 0.1 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.8 GO:0005548 phospholipid transporter activity(GO:0005548)
0.0 0.5 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.4 GO:0030515 snoRNA binding(GO:0030515)
0.0 1.3 GO:0051117 ATPase binding(GO:0051117)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.6 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.0 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.6 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 1.1 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.2 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.6 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.1 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.0 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.8 PID AURORA A PATHWAY Aurora A signaling
0.0 0.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 1.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 1.9 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 2.1 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 4.1 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.0 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.9 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 2.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.8 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.6 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.6 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 1.0 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.5 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.4 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 2.0 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.8 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.2 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.5 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.6 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor