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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for SOX18

Z-value: 0.44

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Transcription factors associated with SOX18

Gene Symbol Gene ID Gene Info
SOX18
ENSG00000203883.5 SRY-box transcription factor 18

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX18hg19_v2_chr20_-_62680984_626809990.311.3e-01Click!

Activity profile of SOX18 motif

Sorted Z-values of SOX18 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_156588115 1.47 ENST00000455639.2
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr4_+_156588249 1.03 ENST00000393832.3
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr6_-_13487784 0.62 ENST00000379287.3
GFOD1
glucose-fructose oxidoreductase domain containing 1
chr3_+_20081515 0.59 ENST00000263754.4
KAT2B
K(lysine) acetyltransferase 2B
chr11_+_71238313 0.54 ENST00000398536.4
KRTAP5-7
keratin associated protein 5-7
chr6_-_26235206 0.47 ENST00000244534.5
HIST1H1D
histone cluster 1, H1d
chrX_+_10031499 0.45 ENST00000454666.1
WWC3
WWC family member 3
chr16_-_68034470 0.43 ENST00000412757.2
DPEP2
dipeptidase 2
chrX_-_117119243 0.43 ENST00000539496.1
ENST00000469946.1
KLHL13
kelch-like family member 13
chr7_-_150329421 0.43 ENST00000493969.1
ENST00000328902.5
GIMAP6
GTPase, IMAP family member 6
chr19_-_42006539 0.42 ENST00000597702.1
ENST00000588495.1
ENST00000595837.1
ENST00000594315.1
AC011526.1
AC011526.1
chr3_-_93692781 0.41 ENST00000394236.3
PROS1
protein S (alpha)
chr7_+_12727250 0.38 ENST00000404894.1
ARL4A
ADP-ribosylation factor-like 4A
chr5_-_31532160 0.38 ENST00000511367.2
ENST00000513349.1
DROSHA
drosha, ribonuclease type III
chr2_+_1418154 0.37 ENST00000423320.1
ENST00000382198.1
TPO
thyroid peroxidase
chr5_+_148960931 0.34 ENST00000333677.6
ARHGEF37
Rho guanine nucleotide exchange factor (GEF) 37
chr5_-_66492562 0.33 ENST00000256447.4
CD180
CD180 molecule
chr8_-_86253888 0.32 ENST00000522389.1
ENST00000432364.2
ENST00000517618.1
CA1
carbonic anhydrase I
chr6_-_110500905 0.31 ENST00000392587.2
WASF1
WAS protein family, member 1
chr11_+_123986069 0.29 ENST00000456829.2
ENST00000361352.5
ENST00000449321.1
ENST00000392748.1
ENST00000360334.4
ENST00000392744.4
VWA5A
von Willebrand factor A domain containing 5A
chr13_-_45992473 0.29 ENST00000539591.1
ENST00000519676.1
ENST00000519547.1
SLC25A30
solute carrier family 25, member 30
chr12_-_104443890 0.29 ENST00000547583.1
ENST00000360814.4
ENST00000546851.1
GLT8D2
glycosyltransferase 8 domain containing 2
chr16_-_28550320 0.28 ENST00000395641.2
NUPR1
nuclear protein, transcriptional regulator, 1
chr12_+_32260085 0.28 ENST00000548411.1
ENST00000281474.5
ENST00000551086.1
BICD1
bicaudal D homolog 1 (Drosophila)
chr11_-_89223883 0.27 ENST00000528341.1
NOX4
NADPH oxidase 4
chr11_-_89224488 0.26 ENST00000534731.1
ENST00000527626.1
NOX4
NADPH oxidase 4
chr5_-_55412774 0.26 ENST00000434982.2
ANKRD55
ankyrin repeat domain 55
chr7_+_141811539 0.26 ENST00000550469.2
ENST00000477922.3
RP11-1220K2.2
Putative inactive maltase-glucoamylase-like protein LOC93432
chr8_+_11225911 0.26 ENST00000284481.3
C8orf12
chromosome 8 open reading frame 12
chr12_-_15942503 0.25 ENST00000281172.5
EPS8
epidermal growth factor receptor pathway substrate 8
chr9_+_33629119 0.25 ENST00000331828.4
TRBV21OR9-2
T cell receptor beta variable 21/OR9-2 (pseudogene)
chr11_-_89224139 0.25 ENST00000413594.2
NOX4
NADPH oxidase 4
chr11_-_89224508 0.25 ENST00000525196.1
NOX4
NADPH oxidase 4
chr11_-_89224299 0.25 ENST00000343727.5
ENST00000531342.1
ENST00000375979.3
NOX4
NADPH oxidase 4
chr4_+_164265035 0.24 ENST00000338566.3
NPY5R
neuropeptide Y receptor Y5
chr2_+_1488435 0.24 ENST00000446278.1
ENST00000469607.1
TPO
thyroid peroxidase
chr8_+_62737875 0.24 ENST00000523042.1
ENST00000518593.1
ENST00000519452.1
ENST00000519967.1
RP11-705O24.1
RP11-705O24.1
chr8_-_27469196 0.23 ENST00000546343.1
ENST00000560566.1
CLU
clusterin
chr19_-_55453077 0.23 ENST00000328092.5
ENST00000590030.1
NLRP7
NLR family, pyrin domain containing 7
chr22_+_27017921 0.22 ENST00000354760.3
CRYBA4
crystallin, beta A4
chr7_-_142120321 0.22 ENST00000390377.1
TRBV7-7
T cell receptor beta variable 7-7
chr8_-_27468842 0.21 ENST00000523500.1
CLU
clusterin
chr19_+_8117636 0.21 ENST00000253451.4
ENST00000315626.4
CCL25
chemokine (C-C motif) ligand 25
chr13_-_44735393 0.21 ENST00000400419.1
SMIM2
small integral membrane protein 2
chr12_-_772901 0.20 ENST00000305108.4
NINJ2
ninjurin 2
chr11_-_75236867 0.20 ENST00000376282.3
ENST00000336898.3
GDPD5
glycerophosphodiester phosphodiesterase domain containing 5
chrX_+_9754461 0.20 ENST00000380913.3
SHROOM2
shroom family member 2
chr6_+_25652501 0.20 ENST00000334979.6
SCGN
secretagogin, EF-hand calcium binding protein
chr19_+_1249869 0.19 ENST00000591446.2
MIDN
midnolin
chr15_+_75628232 0.19 ENST00000267935.8
ENST00000567195.1
COMMD4
COMM domain containing 4
chrX_-_2847366 0.19 ENST00000381154.1
ARSD
arylsulfatase D
chr2_-_54014055 0.18 ENST00000263634.3
ENST00000406687.1
GPR75-ASB3
GPR75-ASB3 readthrough
chr2_+_101591314 0.18 ENST00000450763.1
NPAS2
neuronal PAS domain protein 2
chr8_-_4852494 0.18 ENST00000520002.1
ENST00000602557.1
CSMD1
CUB and Sushi multiple domains 1
chr17_-_39296739 0.17 ENST00000345847.4
KRTAP4-6
keratin associated protein 4-6
chr1_+_15256230 0.17 ENST00000376028.4
ENST00000400798.2
KAZN
kazrin, periplakin interacting protein
chr4_+_109541772 0.17 ENST00000506397.1
ENST00000394668.2
RPL34
ribosomal protein L34
chr4_-_39367949 0.16 ENST00000503784.1
ENST00000349703.2
ENST00000381897.1
RFC1
replication factor C (activator 1) 1, 145kDa
chr1_+_33231268 0.15 ENST00000373480.1
KIAA1522
KIAA1522
chr10_-_13390270 0.15 ENST00000378614.4
ENST00000545675.1
ENST00000327347.5
SEPHS1
selenophosphate synthetase 1
chr17_-_43502987 0.15 ENST00000376922.2
ARHGAP27
Rho GTPase activating protein 27
chrX_+_2984874 0.15 ENST00000359361.2
ARSF
arylsulfatase F
chr11_+_134201911 0.14 ENST00000389881.3
GLB1L2
galactosidase, beta 1-like 2
chr7_-_6048650 0.14 ENST00000382321.4
ENST00000406569.3
PMS2
PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
chr17_-_2966901 0.14 ENST00000575751.1
OR1D5
olfactory receptor, family 1, subfamily D, member 5
chr8_-_4852218 0.14 ENST00000400186.3
ENST00000602723.1
CSMD1
CUB and Sushi multiple domains 1
chr15_+_62359175 0.13 ENST00000355522.5
C2CD4A
C2 calcium-dependent domain containing 4A
chr5_+_147648393 0.13 ENST00000511106.1
ENST00000398450.4
SPINK13
serine peptidase inhibitor, Kazal type 13 (putative)
chr16_+_24549014 0.13 ENST00000564314.1
ENST00000567686.1
RBBP6
retinoblastoma binding protein 6
chr2_-_47382414 0.13 ENST00000294947.2
C2orf61
chromosome 2 open reading frame 61
chr2_-_165811756 0.13 ENST00000409662.1
SLC38A11
solute carrier family 38, member 11
chr7_+_99933730 0.13 ENST00000610247.1
PILRB
paired immunoglobin-like type 2 receptor beta
chrX_+_55744228 0.13 ENST00000262850.7
RRAGB
Ras-related GTP binding B
chr9_+_117350009 0.13 ENST00000374050.3
ATP6V1G1
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1
chr2_+_202125219 0.13 ENST00000323492.7
CASP8
caspase 8, apoptosis-related cysteine peptidase
chr11_-_111749767 0.13 ENST00000542429.1
FDXACB1
ferredoxin-fold anticodon binding domain containing 1
chrX_+_55744166 0.12 ENST00000374941.4
ENST00000414239.1
RRAGB
Ras-related GTP binding B
chr9_-_99064429 0.12 ENST00000375263.3
HSD17B3
hydroxysteroid (17-beta) dehydrogenase 3
chr22_-_31324215 0.12 ENST00000429468.1
MORC2
MORC family CW-type zinc finger 2
chr16_+_28770025 0.12 ENST00000435324.2
NPIPB9
nuclear pore complex interacting protein family, member B9
chrX_-_154033661 0.12 ENST00000393531.1
MPP1
membrane protein, palmitoylated 1, 55kDa
chr1_+_248185250 0.12 ENST00000355281.1
OR2L5
olfactory receptor, family 2, subfamily L, member 5
chr17_-_54893250 0.12 ENST00000397862.2
C17orf67
chromosome 17 open reading frame 67
chr13_-_45992541 0.12 ENST00000522438.1
SLC25A30
solute carrier family 25, member 30
chr4_-_144940477 0.12 ENST00000513128.1
ENST00000429670.2
ENST00000502664.1
GYPB
glycophorin B (MNS blood group)
chr11_-_111749878 0.12 ENST00000260257.4
FDXACB1
ferredoxin-fold anticodon binding domain containing 1
chr7_-_6048702 0.12 ENST00000265849.7
PMS2
PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
chr12_-_71148413 0.12 ENST00000440835.2
ENST00000549308.1
ENST00000550661.1
PTPRR
protein tyrosine phosphatase, receptor type, R
chr19_+_44576296 0.11 ENST00000421176.3
ZNF284
zinc finger protein 284
chr9_-_99064386 0.11 ENST00000375262.2
HSD17B3
hydroxysteroid (17-beta) dehydrogenase 3
chr12_-_71148357 0.11 ENST00000378778.1
PTPRR
protein tyrosine phosphatase, receptor type, R
chr1_-_201123586 0.11 ENST00000414605.2
ENST00000367334.5
ENST00000367332.1
TMEM9
transmembrane protein 9
chr11_+_76156045 0.10 ENST00000533988.1
ENST00000524490.1
ENST00000334736.3
ENST00000343878.3
ENST00000533972.1
C11orf30
chromosome 11 open reading frame 30
chr19_-_57347415 0.10 ENST00000601070.1
ZIM2
zinc finger, imprinted 2
chr5_-_52405564 0.10 ENST00000510818.2
ENST00000396954.3
ENST00000508922.1
ENST00000361377.4
ENST00000582677.1
ENST00000584946.1
ENST00000450852.3
MOCS2
molybdenum cofactor synthesis 2
chr17_+_72427477 0.10 ENST00000342648.5
ENST00000481232.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr3_+_57881966 0.10 ENST00000495364.1
SLMAP
sarcolemma associated protein
chr19_-_56343353 0.10 ENST00000592953.1
ENST00000589093.1
NLRP11
NLR family, pyrin domain containing 11
chr4_+_109541740 0.10 ENST00000394665.1
RPL34
ribosomal protein L34
chr1_-_114430169 0.09 ENST00000393316.3
BCL2L15
BCL2-like 15
chr12_+_8666126 0.09 ENST00000299665.2
CLEC4D
C-type lectin domain family 4, member D
chr12_-_68647281 0.09 ENST00000328087.4
ENST00000538666.1
IL22
interleukin 22
chr22_+_37678424 0.09 ENST00000248901.6
CYTH4
cytohesin 4
chr10_-_127505167 0.09 ENST00000368786.1
UROS
uroporphyrinogen III synthase
chr7_-_148725733 0.09 ENST00000286091.4
PDIA4
protein disulfide isomerase family A, member 4
chr5_+_32711829 0.09 ENST00000415167.2
NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr1_+_100316041 0.09 ENST00000370165.3
ENST00000370163.3
ENST00000294724.4
AGL
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chr4_+_88529681 0.09 ENST00000399271.1
DSPP
dentin sialophosphoprotein
chr11_-_5248294 0.09 ENST00000335295.4
HBB
hemoglobin, beta
chr1_-_201123546 0.09 ENST00000435310.1
ENST00000485839.2
ENST00000367330.1
TMEM9
transmembrane protein 9
chr4_+_109541722 0.09 ENST00000394667.3
ENST00000502534.1
RPL34
ribosomal protein L34
chr12_+_110338323 0.08 ENST00000312777.5
ENST00000536408.2
TCHP
trichoplein, keratin filament binding
chr21_-_31744557 0.08 ENST00000399889.2
KRTAP13-2
keratin associated protein 13-2
chr11_-_6677018 0.08 ENST00000299441.3
DCHS1
dachsous cadherin-related 1
chr3_-_53878644 0.08 ENST00000481668.1
ENST00000467802.1
CHDH
choline dehydrogenase
chr15_-_81202118 0.08 ENST00000560560.1
RP11-351M8.1
Uncharacterized protein
chrX_-_70329118 0.08 ENST00000374188.3
IL2RG
interleukin 2 receptor, gamma
chr10_+_18429606 0.08 ENST00000324631.7
ENST00000352115.6
ENST00000377328.1
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr5_-_78808617 0.08 ENST00000282260.6
ENST00000508576.1
ENST00000535690.1
HOMER1
homer homolog 1 (Drosophila)
chr5_+_57878859 0.08 ENST00000282878.4
RAB3C
RAB3C, member RAS oncogene family
chr5_-_179050066 0.08 ENST00000329433.6
ENST00000510411.1
HNRNPH1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr3_-_197300194 0.08 ENST00000358186.2
ENST00000431056.1
BDH1
3-hydroxybutyrate dehydrogenase, type 1
chr6_+_26217159 0.08 ENST00000303910.2
HIST1H2AE
histone cluster 1, H2ae
chr15_+_75628394 0.08 ENST00000564815.1
ENST00000338995.6
COMMD4
COMM domain containing 4
chr12_-_75603202 0.08 ENST00000393288.2
KCNC2
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr12_+_110338063 0.08 ENST00000405876.4
TCHP
trichoplein, keratin filament binding
chr12_-_10562356 0.08 ENST00000309384.1
KLRC4
killer cell lectin-like receptor subfamily C, member 4
chr5_+_54398463 0.07 ENST00000274306.6
GZMA
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
chr11_-_76155700 0.07 ENST00000572035.1
RP11-111M22.3
RP11-111M22.3
chr12_-_56321397 0.07 ENST00000557259.1
ENST00000549939.1
WIBG
within bgcn homolog (Drosophila)
chr13_-_53024725 0.07 ENST00000378060.4
VPS36
vacuolar protein sorting 36 homolog (S. cerevisiae)
chr8_-_21669826 0.07 ENST00000517328.1
GFRA2
GDNF family receptor alpha 2
chrX_+_135618258 0.07 ENST00000440515.1
ENST00000456412.1
VGLL1
vestigial like 1 (Drosophila)
chr2_+_210517895 0.07 ENST00000447185.1
MAP2
microtubule-associated protein 2
chr6_+_42883727 0.07 ENST00000304672.1
ENST00000441198.1
ENST00000446507.1
PTCRA
pre T-cell antigen receptor alpha
chr15_+_75628419 0.07 ENST00000567377.1
ENST00000562789.1
ENST00000568301.1
COMMD4
COMM domain containing 4
chr5_+_31532373 0.07 ENST00000325366.9
ENST00000355907.3
ENST00000507818.2
C5orf22
chromosome 5 open reading frame 22
chr2_+_234621551 0.07 ENST00000608381.1
ENST00000373414.3
UGT1A1
UGT1A5
UDP glucuronosyltransferase 1 family, polypeptide A8
UDP glucuronosyltransferase 1 family, polypeptide A5
chr2_+_44502597 0.07 ENST00000260649.6
ENST00000409387.1
SLC3A1
solute carrier family 3 (amino acid transporter heavy chain), member 1
chr3_+_145782358 0.07 ENST00000422482.1
AC107021.1
HCG1786590; PRO2533; Uncharacterized protein
chr8_-_146176199 0.07 ENST00000532351.1
ENST00000276816.4
ENST00000394909.2
ZNF16
zinc finger protein 16
chr5_+_99871004 0.07 ENST00000312637.4
FAM174A
family with sequence similarity 174, member A
chr3_+_186435137 0.07 ENST00000447445.1
KNG1
kininogen 1
chrX_+_85969626 0.06 ENST00000484479.1
DACH2
dachshund homolog 2 (Drosophila)
chr2_-_40739501 0.06 ENST00000403092.1
ENST00000402441.1
ENST00000448531.1
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr6_-_75953484 0.06 ENST00000472311.2
ENST00000460985.1
ENST00000377978.3
ENST00000509698.1
ENST00000230459.4
ENST00000370089.2
COX7A2
cytochrome c oxidase subunit VIIa polypeptide 2 (liver)
chr10_-_8095412 0.06 ENST00000458727.1
ENST00000355358.1
RP11-379F12.3
GATA3-AS1
RP11-379F12.3
GATA3 antisense RNA 1
chr1_+_161123536 0.06 ENST00000368003.5
UFC1
ubiquitin-fold modifier conjugating enzyme 1
chr1_-_155881156 0.06 ENST00000539040.1
ENST00000368323.3
RIT1
Ras-like without CAAX 1
chr20_-_44718538 0.06 ENST00000290231.6
ENST00000372291.3
NCOA5
nuclear receptor coactivator 5
chr11_-_76155618 0.06 ENST00000530759.1
RP11-111M22.3
RP11-111M22.3
chr11_+_4664650 0.06 ENST00000396952.5
OR51E1
olfactory receptor, family 51, subfamily E, member 1
chr1_+_225600404 0.06 ENST00000366845.2
AC092811.1
AC092811.1
chr12_-_48963829 0.06 ENST00000301046.2
ENST00000549817.1
LALBA
lactalbumin, alpha-
chr19_+_48497901 0.06 ENST00000339841.2
ELSPBP1
epididymal sperm binding protein 1
chr1_-_11918988 0.06 ENST00000376468.3
NPPB
natriuretic peptide B
chr6_+_89790490 0.06 ENST00000336032.3
PNRC1
proline-rich nuclear receptor coactivator 1
chr12_-_8088871 0.06 ENST00000075120.7
SLC2A3
solute carrier family 2 (facilitated glucose transporter), member 3
chr1_+_34326076 0.06 ENST00000519684.1
ENST00000522796.1
HMGB4
high mobility group box 4
chr2_+_170590321 0.06 ENST00000392647.2
KLHL23
kelch-like family member 23
chr4_-_57524061 0.05 ENST00000508121.1
HOPX
HOP homeobox
chr3_+_111451321 0.05 ENST00000393923.3
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr14_+_22217447 0.05 ENST00000390427.3
TRAV5
T cell receptor alpha variable 5
chr7_-_33080506 0.05 ENST00000381626.2
ENST00000409467.1
ENST00000449201.1
NT5C3A
5'-nucleotidase, cytosolic IIIA
chr19_+_57742431 0.05 ENST00000302804.7
AURKC
aurora kinase C
chr4_+_54243798 0.05 ENST00000337488.6
ENST00000358575.5
ENST00000507922.1
FIP1L1
factor interacting with PAPOLA and CPSF1
chr9_-_21351377 0.05 ENST00000380210.1
IFNA6
interferon, alpha 6
chr15_+_44084040 0.05 ENST00000249786.4
SERF2
small EDRK-rich factor 2
chr7_-_122840015 0.05 ENST00000194130.2
SLC13A1
solute carrier family 13 (sodium/sulfate symporter), member 1
chr1_+_22979474 0.05 ENST00000509305.1
C1QB
complement component 1, q subcomponent, B chain
chr6_+_89790459 0.05 ENST00000369472.1
PNRC1
proline-rich nuclear receptor coactivator 1
chr1_-_156828810 0.05 ENST00000368195.3
INSRR
insulin receptor-related receptor
chr12_-_75603236 0.05 ENST00000540018.1
KCNC2
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr8_+_119294456 0.05 ENST00000366457.2
AC023590.1
Uncharacterized protein
chr1_+_36348790 0.04 ENST00000373204.4
AGO1
argonaute RISC catalytic component 1
chr6_-_33385870 0.04 ENST00000488034.1
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr4_-_109541539 0.04 ENST00000509984.1
ENST00000507248.1
ENST00000506795.1
RPL34-AS1
RPL34 antisense RNA 1 (head to head)
chr2_+_87135076 0.04 ENST00000409776.2
RGPD1
RANBP2-like and GRIP domain containing 1
chr16_-_79015739 0.04 ENST00000594986.1
PIH1
HCG1979943; Uncharacterized protein
chr1_+_66258846 0.04 ENST00000341517.4
PDE4B
phosphodiesterase 4B, cAMP-specific
chr12_-_75603643 0.04 ENST00000549446.1
KCNC2
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr16_-_787771 0.04 ENST00000568545.1
NARFL
nuclear prelamin A recognition factor-like
chr9_+_33240157 0.04 ENST00000379721.3
SPINK4
serine peptidase inhibitor, Kazal type 4
chr15_-_64385981 0.04 ENST00000557835.1
ENST00000380290.3
ENST00000559950.1
FAM96A
family with sequence similarity 96, member A
chr11_-_118047376 0.04 ENST00000278947.5
SCN2B
sodium channel, voltage-gated, type II, beta subunit
chr3_-_120003941 0.04 ENST00000464295.1
GPR156
G protein-coupled receptor 156
chr1_-_12958101 0.04 ENST00000235347.4
PRAMEF10
PRAME family member 10
chr12_-_75603482 0.04 ENST00000341669.3
ENST00000298972.1
ENST00000350228.2
KCNC2
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr1_-_45988542 0.04 ENST00000424390.1
PRDX1
peroxiredoxin 1
chr8_+_40010989 0.04 ENST00000315792.3
C8orf4
chromosome 8 open reading frame 4
chr3_+_186435065 0.04 ENST00000287611.2
ENST00000265023.4
KNG1
kininogen 1
chr6_-_33385854 0.04 ENST00000488478.1
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr5_+_156607829 0.04 ENST00000422843.3
ITK
IL2-inducible T-cell kinase
chr9_-_74525658 0.04 ENST00000333421.6
ABHD17B
abhydrolase domain containing 17B
chr15_-_64386120 0.04 ENST00000300030.3
FAM96A
family with sequence similarity 96, member A
chr2_-_105953912 0.04 ENST00000610036.1
RP11-332H14.2
RP11-332H14.2
chr2_+_74881355 0.04 ENST00000357877.2
SEMA4F
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
chr12_-_10573149 0.04 ENST00000381904.2
ENST00000381903.2
ENST00000396439.2
KLRC3
killer cell lectin-like receptor subfamily C, member 3
chr7_-_42951509 0.04 ENST00000438029.1
ENST00000432637.1
ENST00000447342.1
ENST00000431882.2
ENST00000350427.4
ENST00000425683.1
C7orf25
chromosome 7 open reading frame 25
chr11_+_20620946 0.04 ENST00000525748.1
SLC6A5
solute carrier family 6 (neurotransmitter transporter), member 5

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX18

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.5 GO:0052565 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.1 0.6 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076) positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.1 0.3 GO:1900276 regulation of proteinase activated receptor activity(GO:1900276) negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900737)
0.1 0.4 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.1 0.3 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.1 0.5 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.1 0.2 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.1 0.3 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.5 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.2 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0 0.4 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 1.3 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.2 GO:0032229 negative regulation of glutamate secretion(GO:0014050) negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.0 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.2 GO:0061370 testosterone biosynthetic process(GO:0061370)
0.0 0.2 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.2 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.1 GO:0039516 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.0 0.3 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.1 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.0 0.3 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 0.1 GO:0003192 mitral valve formation(GO:0003192)
0.0 0.1 GO:0031456 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.0 0.1 GO:1901535 regulation of DNA demethylation(GO:1901535)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.2 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0 0.4 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.1 GO:0060467 negative regulation of fertilization(GO:0060467)
0.0 0.1 GO:0030185 nitric oxide transport(GO:0030185)
0.0 0.6 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.1 GO:0005989 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.3 GO:2000194 regulation of female gonad development(GO:2000194)
0.0 0.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.2 GO:0048505 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0 0.3 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.1 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.1 GO:0070980 biphenyl catabolic process(GO:0070980)
0.0 0.2 GO:0045176 apical protein localization(GO:0045176)
0.0 0.0 GO:0071469 cellular response to alkaline pH(GO:0071469)
0.0 0.1 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.0 0.1 GO:1990822 L-cystine transport(GO:0015811) basic amino acid transmembrane transport(GO:1990822)
0.0 0.1 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0039713 viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517)
0.1 2.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 1.3 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.6 GO:0000125 PCAF complex(GO:0000125)
0.0 0.2 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.1 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.3 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.3 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.1 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.0 0.4 GO:0097418 neurofibrillary tangle(GO:0097418)
0.0 0.1 GO:0000814 ESCRT II complex(GO:0000814)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.2 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.5 GO:0005719 nuclear euchromatin(GO:0005719)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0004447 iodide peroxidase activity(GO:0004447)
0.1 2.5 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 1.3 GO:0019826 oxygen sensor activity(GO:0019826)
0.1 0.4 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1 0.2 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.5 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 0.2 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.1 0.2 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.0 0.3 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.2 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.0 0.3 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.2 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0 0.3 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.1 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.0 0.1 GO:0045518 interleukin-22 receptor binding(GO:0045518)
0.0 0.1 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.0 0.1 GO:0004917 interleukin-4 receptor activity(GO:0004913) interleukin-7 receptor activity(GO:0004917)
0.0 0.1 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 0.4 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.2 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.1 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.1 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.1 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.1 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.0 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.3 PID PTP1B PATHWAY Signaling events mediated by PTP1B

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 2.5 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.4 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.5 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.5 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.2 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.4 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis