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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for SOX4

Z-value: 0.79

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Transcription factors associated with SOX4

Gene Symbol Gene ID Gene Info
SOX4
ENSG00000124766.4 SRY-box transcription factor 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX4hg19_v2_chr6_+_21593972_215940710.491.2e-02Click!

Activity profile of SOX4 motif

Sorted Z-values of SOX4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_186877502 2.79 ENST00000431902.1
ENST00000284776.7
ENST00000415274.1
SORBS2
sorbin and SH3 domain containing 2
chr20_-_39317868 2.72 ENST00000373313.2
MAFB
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
chr8_-_80993010 2.28 ENST00000537855.1
ENST00000520527.1
ENST00000517427.1
ENST00000448733.2
ENST00000379097.3
TPD52
tumor protein D52
chr4_-_159080806 1.94 ENST00000590648.1
FAM198B
family with sequence similarity 198, member B
chr5_-_111091948 1.91 ENST00000447165.2
NREP
neuronal regeneration related protein
chr11_-_10829851 1.86 ENST00000532082.1
EIF4G2
eukaryotic translation initiation factor 4 gamma, 2
chr3_+_141105235 1.82 ENST00000503809.1
ZBTB38
zinc finger and BTB domain containing 38
chr9_-_14313641 1.64 ENST00000380953.1
NFIB
nuclear factor I/B
chr12_+_93963590 1.52 ENST00000340600.2
SOCS2
suppressor of cytokine signaling 2
chr16_+_30406721 1.49 ENST00000320159.2
ZNF48
zinc finger protein 48
chr5_-_39425222 1.48 ENST00000320816.6
DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chrX_-_63005405 1.44 ENST00000374878.1
ENST00000437457.2
ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr5_-_39425068 1.39 ENST00000515700.1
ENST00000339788.6
DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr5_-_39425290 1.36 ENST00000545653.1
DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr2_+_33172221 1.35 ENST00000354476.3
LTBP1
latent transforming growth factor beta binding protein 1
chr11_-_10830463 1.30 ENST00000527419.1
ENST00000530211.1
ENST00000530702.1
ENST00000524932.1
ENST00000532570.1
EIF4G2
eukaryotic translation initiation factor 4 gamma, 2
chr1_+_97188188 1.29 ENST00000541987.1
PTBP2
polypyrimidine tract binding protein 2
chr7_-_27219849 1.26 ENST00000396344.4
HOXA10
homeobox A10
chr10_+_18948311 1.26 ENST00000377275.3
ARL5B
ADP-ribosylation factor-like 5B
chr8_-_17579726 1.25 ENST00000381861.3
MTUS1
microtubule associated tumor suppressor 1
chr9_-_14313893 1.25 ENST00000380921.3
ENST00000380959.3
NFIB
nuclear factor I/B
chr18_+_6729698 1.23 ENST00000383472.4
ARHGAP28
Rho GTPase activating protein 28
chr17_+_67498538 1.19 ENST00000589647.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr20_+_30598231 1.18 ENST00000300415.8
ENST00000262659.8
CCM2L
cerebral cavernous malformation 2-like
chr8_-_6420565 1.11 ENST00000338312.6
ANGPT2
angiopoietin 2
chr1_-_85930246 1.09 ENST00000426972.3
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr15_+_25200108 1.07 ENST00000577949.1
ENST00000338094.6
ENST00000338327.4
ENST00000579070.1
ENST00000577565.1
SNURF
SNRPN
SNRPN upstream reading frame protein
small nuclear ribonucleoprotein polypeptide N
chr7_+_116312411 1.03 ENST00000456159.1
ENST00000397752.3
ENST00000318493.6
MET
met proto-oncogene
chr17_+_25621102 1.01 ENST00000581440.1
ENST00000262394.2
ENST00000583742.1
ENST00000579733.1
ENST00000583193.1
ENST00000581185.1
ENST00000427287.2
ENST00000348811.2
WSB1
WD repeat and SOCS box containing 1
chr17_-_14683517 1.01 ENST00000379640.1
AC005863.1
AC005863.1
chr1_+_185703513 0.98 ENST00000271588.4
ENST00000367492.2
HMCN1
hemicentin 1
chr15_+_25200074 0.96 ENST00000390687.4
ENST00000584968.1
ENST00000346403.6
ENST00000554227.2
SNRPN
small nuclear ribonucleoprotein polypeptide N
chr8_-_6420759 0.96 ENST00000523120.1
ANGPT2
angiopoietin 2
chr13_+_39612442 0.90 ENST00000470258.1
ENST00000379600.3
NHLRC3
NHL repeat containing 3
chr2_+_33172012 0.86 ENST00000404816.2
LTBP1
latent transforming growth factor beta binding protein 1
chr13_+_111855414 0.83 ENST00000375737.5
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr8_-_6420930 0.83 ENST00000325203.5
ANGPT2
angiopoietin 2
chr8_-_6420777 0.82 ENST00000415216.1
ANGPT2
angiopoietin 2
chr14_+_69658480 0.82 ENST00000409949.1
ENST00000409242.1
ENST00000312994.5
ENST00000413191.1
EXD2
exonuclease 3'-5' domain containing 2
chr4_+_78079450 0.79 ENST00000395640.1
ENST00000512918.1
CCNG2
cyclin G2
chr4_+_78079570 0.77 ENST00000509972.1
CCNG2
cyclin G2
chr14_+_91580777 0.74 ENST00000525393.2
ENST00000428926.2
ENST00000517362.1
C14orf159
chromosome 14 open reading frame 159
chr14_+_91581011 0.74 ENST00000523894.1
ENST00000522322.1
ENST00000523771.1
C14orf159
chromosome 14 open reading frame 159
chr1_+_66458072 0.73 ENST00000423207.2
PDE4B
phosphodiesterase 4B, cAMP-specific
chr2_-_106015527 0.73 ENST00000344213.4
ENST00000358129.4
FHL2
four and a half LIM domains 2
chr14_+_75746781 0.72 ENST00000555347.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr14_+_91580708 0.67 ENST00000518868.1
C14orf159
chromosome 14 open reading frame 159
chr9_-_74979420 0.64 ENST00000343431.2
ENST00000376956.3
ZFAND5
zinc finger, AN1-type domain 5
chr7_+_115850547 0.63 ENST00000358204.4
ENST00000455989.1
ENST00000537767.1
TES
testis derived transcript (3 LIM domains)
chr9_-_16727978 0.61 ENST00000418777.1
ENST00000468187.2
BNC2
basonuclin 2
chr5_+_140739537 0.59 ENST00000522605.1
PCDHGB2
protocadherin gamma subfamily B, 2
chr7_-_19813192 0.59 ENST00000422233.1
ENST00000433641.1
TMEM196
transmembrane protein 196
chr11_+_46402744 0.57 ENST00000533952.1
MDK
midkine (neurite growth-promoting factor 2)
chr10_-_18948156 0.57 ENST00000414939.1
ENST00000449529.1
ENST00000456217.1
ENST00000444660.1
ARL5B-AS1
ARL5B antisense RNA 1
chr18_+_6729725 0.56 ENST00000400091.2
ENST00000583410.1
ENST00000584387.1
ARHGAP28
Rho GTPase activating protein 28
chr22_+_27017921 0.56 ENST00000354760.3
CRYBA4
crystallin, beta A4
chr5_+_140579162 0.55 ENST00000536699.1
ENST00000354757.3
PCDHB11
protocadherin beta 11
chrX_-_2847366 0.55 ENST00000381154.1
ARSD
arylsulfatase D
chr1_+_207002222 0.54 ENST00000270218.6
IL19
interleukin 19
chr4_+_78078304 0.52 ENST00000316355.5
ENST00000354403.5
ENST00000502280.1
CCNG2
cyclin G2
chr19_+_1249869 0.52 ENST00000591446.2
MIDN
midnolin
chr1_+_81771806 0.50 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2
latrophilin 2
chr2_+_208423840 0.50 ENST00000539789.1
CREB1
cAMP responsive element binding protein 1
chr14_+_24521202 0.49 ENST00000334420.7
ENST00000342740.5
LRRC16B
leucine rich repeat containing 16B
chr1_+_228337553 0.49 ENST00000366714.2
GJC2
gap junction protein, gamma 2, 47kDa
chr12_+_132379160 0.49 ENST00000321867.4
ULK1
unc-51 like autophagy activating kinase 1
chr19_-_17375527 0.49 ENST00000431146.2
ENST00000594190.1
USHBP1
Usher syndrome 1C binding protein 1
chr19_+_10765699 0.48 ENST00000590009.1
ILF3
interleukin enhancer binding factor 3, 90kDa
chr9_+_91003271 0.47 ENST00000375859.3
ENST00000541629.1
SPIN1
spindlin 1
chr14_-_51027838 0.45 ENST00000555216.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr15_+_65823092 0.44 ENST00000566074.1
PTPLAD1
protein tyrosine phosphatase-like A domain containing 1
chr5_+_140749803 0.43 ENST00000576222.1
PCDHGB3
protocadherin gamma subfamily B, 3
chr15_+_65822756 0.43 ENST00000562901.1
ENST00000261875.5
ENST00000442729.2
ENST00000565299.1
ENST00000568793.1
PTPLAD1
protein tyrosine phosphatase-like A domain containing 1
chr7_-_148581360 0.43 ENST00000320356.2
ENST00000541220.1
ENST00000483967.1
ENST00000536783.1
EZH2
enhancer of zeste homolog 2 (Drosophila)
chr7_-_107643674 0.42 ENST00000222399.6
LAMB1
laminin, beta 1
chr12_+_32260085 0.42 ENST00000548411.1
ENST00000281474.5
ENST00000551086.1
BICD1
bicaudal D homolog 1 (Drosophila)
chr18_+_56530794 0.42 ENST00000590285.1
ENST00000586085.1
ENST00000589288.1
ZNF532
zinc finger protein 532
chr16_+_14980632 0.41 ENST00000565655.1
NOMO1
NODAL modulator 1
chr5_+_102201509 0.40 ENST00000348126.2
ENST00000379787.4
PAM
peptidylglycine alpha-amidating monooxygenase
chr20_+_45338126 0.40 ENST00000359271.2
SLC2A10
solute carrier family 2 (facilitated glucose transporter), member 10
chr7_-_148581251 0.39 ENST00000478654.1
ENST00000460911.1
ENST00000350995.2
EZH2
enhancer of zeste homolog 2 (Drosophila)
chr11_-_62414070 0.39 ENST00000540933.1
ENST00000346178.4
ENST00000356638.3
ENST00000534779.1
ENST00000525994.1
GANAB
glucosidase, alpha; neutral AB
chr20_-_17511962 0.38 ENST00000377873.3
BFSP1
beaded filament structural protein 1, filensin
chr2_+_208423891 0.37 ENST00000448277.1
ENST00000457101.1
CREB1
cAMP responsive element binding protein 1
chr8_-_95908902 0.36 ENST00000520509.1
CCNE2
cyclin E2
chr11_-_94965667 0.35 ENST00000542176.1
ENST00000278499.2
SESN3
sestrin 3
chr15_-_34502197 0.34 ENST00000557877.1
KATNBL1
katanin p80 subunit B-like 1
chr18_+_7946941 0.34 ENST00000444013.1
PTPRM
protein tyrosine phosphatase, receptor type, M
chr22_-_31688381 0.32 ENST00000487265.2
PIK3IP1
phosphoinositide-3-kinase interacting protein 1
chr4_-_22444733 0.31 ENST00000508133.1
GPR125
G protein-coupled receptor 125
chr4_+_106629929 0.31 ENST00000512828.1
ENST00000394730.3
ENST00000507281.1
ENST00000515279.1
GSTCD
glutathione S-transferase, C-terminal domain containing
chr10_+_22605374 0.31 ENST00000448361.1
COMMD3
COMM domain containing 3
chr7_+_134551583 0.31 ENST00000435928.1
CALD1
caldesmon 1
chr10_+_22605304 0.31 ENST00000475460.2
ENST00000602390.1
ENST00000489125.2
ENST00000456711.1
ENST00000444869.1
COMMD3-BMI1
COMMD3
COMMD3-BMI1 readthrough
COMM domain containing 3
chr14_+_69658194 0.31 ENST00000409018.3
ENST00000409014.1
ENST00000409675.1
EXD2
exonuclease 3'-5' domain containing 2
chr19_+_1248547 0.30 ENST00000586757.1
ENST00000300952.2
MIDN
midnolin
chr1_+_150039369 0.30 ENST00000369130.3
ENST00000369128.5
VPS45
vacuolar protein sorting 45 homolog (S. cerevisiae)
chr5_+_102201430 0.29 ENST00000438793.3
ENST00000346918.2
PAM
peptidylglycine alpha-amidating monooxygenase
chrX_-_24690771 0.29 ENST00000379145.1
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr7_+_139528952 0.28 ENST00000416849.2
ENST00000436047.2
ENST00000414508.2
ENST00000448866.1
TBXAS1
thromboxane A synthase 1 (platelet)
chr14_+_101299520 0.28 ENST00000455531.1
MEG3
maternally expressed 3 (non-protein coding)
chr19_-_17375541 0.28 ENST00000252597.3
USHBP1
Usher syndrome 1C binding protein 1
chr1_-_93645818 0.27 ENST00000370280.1
ENST00000479918.1
TMED5
transmembrane emp24 protein transport domain containing 5
chr11_-_6677018 0.27 ENST00000299441.3
DCHS1
dachsous cadherin-related 1
chr14_-_31676674 0.26 ENST00000399332.1
ENST00000556224.1
HECTD1
HECT domain containing E3 ubiquitin protein ligase 1
chr3_+_50649302 0.26 ENST00000446044.1
MAPKAPK3
mitogen-activated protein kinase-activated protein kinase 3
chr14_-_20923195 0.26 ENST00000206542.4
OSGEP
O-sialoglycoprotein endopeptidase
chr8_-_16043780 0.25 ENST00000445506.2
MSR1
macrophage scavenger receptor 1
chr6_-_132834184 0.25 ENST00000367941.2
ENST00000367937.4
STX7
syntaxin 7
chr14_-_73493784 0.24 ENST00000553891.1
ZFYVE1
zinc finger, FYVE domain containing 1
chr14_+_50234827 0.23 ENST00000554589.1
ENST00000557247.1
KLHDC2
kelch domain containing 2
chr5_+_93954039 0.22 ENST00000265140.5
ANKRD32
ankyrin repeat domain 32
chr1_-_32801825 0.22 ENST00000329421.7
MARCKSL1
MARCKS-like 1
chr4_-_69111401 0.21 ENST00000332644.5
TMPRSS11B
transmembrane protease, serine 11B
chr4_+_71588372 0.21 ENST00000536664.1
RUFY3
RUN and FYVE domain containing 3
chr1_-_26233423 0.21 ENST00000357865.2
STMN1
stathmin 1
chr14_+_91580732 0.21 ENST00000519019.1
ENST00000523816.1
ENST00000517518.1
C14orf159
chromosome 14 open reading frame 159
chr3_+_159570722 0.20 ENST00000482804.1
SCHIP1
schwannomin interacting protein 1
chr1_+_93645314 0.20 ENST00000343253.7
CCDC18
coiled-coil domain containing 18
chr12_+_109915179 0.20 ENST00000434735.2
UBE3B
ubiquitin protein ligase E3B
chr16_-_31085033 0.19 ENST00000414399.1
ZNF668
zinc finger protein 668
chrX_-_73512411 0.19 ENST00000602576.1
ENST00000429124.1
FTX
FTX transcript, XIST regulator (non-protein coding)
chr17_+_59489112 0.18 ENST00000335108.2
C17orf82
chromosome 17 open reading frame 82
chr4_+_2819883 0.18 ENST00000511747.1
ENST00000503393.2
SH3BP2
SH3-domain binding protein 2
chrX_+_51927919 0.18 ENST00000416960.1
MAGED4
melanoma antigen family D, 4
chr16_+_72088376 0.18 ENST00000570083.1
ENST00000355906.5
ENST00000398131.2
ENST00000569639.1
ENST00000564499.1
ENST00000357763.4
ENST00000562526.1
ENST00000565574.1
ENST00000568417.2
ENST00000356967.5
HP
HPR
haptoglobin
haptoglobin-related protein
chr3_-_50649192 0.18 ENST00000443053.2
ENST00000348721.3
CISH
cytokine inducible SH2-containing protein
chr14_-_73493825 0.18 ENST00000318876.5
ENST00000556143.1
ZFYVE1
zinc finger, FYVE domain containing 1
chrX_-_135962876 0.17 ENST00000431446.3
ENST00000570135.1
ENST00000320676.7
ENST00000562646.1
RBMX
RNA binding motif protein, X-linked
chr12_-_10282742 0.17 ENST00000298523.5
ENST00000396484.2
ENST00000310002.4
CLEC7A
C-type lectin domain family 7, member A
chr15_-_45670924 0.17 ENST00000396659.3
GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr1_+_28261492 0.16 ENST00000373894.3
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr12_-_48963829 0.16 ENST00000301046.2
ENST00000549817.1
LALBA
lactalbumin, alpha-
chr7_-_35293740 0.16 ENST00000408931.3
TBX20
T-box 20
chr21_+_30671690 0.15 ENST00000399921.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr9_-_39239171 0.15 ENST00000358144.2
CNTNAP3
contactin associated protein-like 3
chrX_+_36053908 0.15 ENST00000378660.2
CHDC2
calponin homology domain containing 2
chr1_+_28844778 0.15 ENST00000411533.1
RCC1
regulator of chromosome condensation 1
chr2_+_223536428 0.15 ENST00000446656.3
MOGAT1
monoacylglycerol O-acyltransferase 1
chr5_+_140480083 0.14 ENST00000231130.2
PCDHB3
protocadherin beta 3
chr1_+_109419596 0.14 ENST00000435987.1
ENST00000264126.3
GPSM2
G-protein signaling modulator 2
chr9_+_124088860 0.14 ENST00000373806.1
GSN
gelsolin
chr3_+_57875711 0.14 ENST00000442599.2
SLMAP
sarcolemma associated protein
chr15_+_75940218 0.14 ENST00000308527.5
SNX33
sorting nexin 33
chr8_+_9911778 0.13 ENST00000317173.4
ENST00000441698.2
MSRA
methionine sulfoxide reductase A
chr4_+_159690218 0.13 ENST00000264433.6
FNIP2
folliculin interacting protein 2
chr7_-_42276612 0.13 ENST00000395925.3
ENST00000437480.1
GLI3
GLI family zinc finger 3
chr12_-_10282836 0.13 ENST00000304084.8
ENST00000353231.5
ENST00000525605.1
CLEC7A
C-type lectin domain family 7, member A
chr1_+_28261621 0.13 ENST00000549094.1
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr1_+_209602771 0.13 ENST00000440276.1
MIR205HG
MIR205 host gene (non-protein coding)
chr3_-_197024965 0.13 ENST00000392382.2
DLG1
discs, large homolog 1 (Drosophila)
chr22_-_31688431 0.13 ENST00000402249.3
ENST00000443175.1
ENST00000215912.5
ENST00000441972.1
PIK3IP1
phosphoinositide-3-kinase interacting protein 1
chrX_+_70503433 0.13 ENST00000276079.8
ENST00000373856.3
ENST00000373841.1
ENST00000420903.1
NONO
non-POU domain containing, octamer-binding
chr20_+_18125727 0.12 ENST00000489634.2
CSRP2BP
CSRP2 binding protein
chr20_+_58533471 0.12 ENST00000244047.5
ENST00000348616.4
CDH26
cadherin 26
chr12_-_122296755 0.12 ENST00000289004.4
HPD
4-hydroxyphenylpyruvate dioxygenase
chr5_+_140767452 0.12 ENST00000519479.1
PCDHGB4
protocadherin gamma subfamily B, 4
chr12_-_95945246 0.12 ENST00000258499.3
USP44
ubiquitin specific peptidase 44
chr1_+_153940713 0.12 ENST00000368601.1
ENST00000368603.1
ENST00000368600.3
CREB3L4
cAMP responsive element binding protein 3-like 4
chr3_-_99833333 0.12 ENST00000354552.3
ENST00000331335.5
ENST00000398326.2
FILIP1L
filamin A interacting protein 1-like
chr12_+_8666126 0.12 ENST00000299665.2
CLEC4D
C-type lectin domain family 4, member D
chr4_-_54424366 0.11 ENST00000306888.2
LNX1
ligand of numb-protein X 1, E3 ubiquitin protein ligase
chr3_-_197024394 0.11 ENST00000434148.1
ENST00000412364.2
ENST00000436682.1
ENST00000456699.2
ENST00000392380.2
DLG1
discs, large homolog 1 (Drosophila)
chr2_-_20425158 0.11 ENST00000381150.1
SDC1
syndecan 1
chr17_-_10372875 0.11 ENST00000255381.2
MYH4
myosin, heavy chain 4, skeletal muscle
chrX_+_12993202 0.11 ENST00000451311.2
ENST00000380636.1
TMSB4X
thymosin beta 4, X-linked
chr1_+_160147176 0.10 ENST00000470705.1
ATP1A4
ATPase, Na+/K+ transporting, alpha 4 polypeptide
chr17_-_72358001 0.10 ENST00000375366.3
BTBD17
BTB (POZ) domain containing 17
chr1_+_153940346 0.10 ENST00000405694.3
ENST00000449724.1
ENST00000368607.3
ENST00000271889.4
CREB3L4
cAMP responsive element binding protein 3-like 4
chr16_+_524850 0.10 ENST00000450428.1
ENST00000452814.1
RAB11FIP3
RAB11 family interacting protein 3 (class II)
chr1_-_152297679 0.10 ENST00000368799.1
FLG
filaggrin
chr1_-_115259337 0.10 ENST00000369535.4
NRAS
neuroblastoma RAS viral (v-ras) oncogene homolog
chr17_+_57297807 0.10 ENST00000284116.4
ENST00000581140.1
ENST00000581276.1
GDPD1
glycerophosphodiester phosphodiesterase domain containing 1
chr12_-_10282681 0.10 ENST00000533022.1
CLEC7A
C-type lectin domain family 7, member A
chr7_-_150946015 0.10 ENST00000262188.8
SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr19_+_49128209 0.10 ENST00000599748.1
ENST00000443164.1
ENST00000599029.1
SPHK2
sphingosine kinase 2
chr11_-_61560053 0.09 ENST00000537328.1
TMEM258
transmembrane protein 258
chrX_-_15683147 0.09 ENST00000380342.3
TMEM27
transmembrane protein 27
chr5_+_140787600 0.09 ENST00000520790.1
PCDHGB6
protocadherin gamma subfamily B, 6
chr14_+_20923350 0.09 ENST00000555414.1
ENST00000216714.3
ENST00000553681.1
ENST00000557344.1
ENST00000398030.4
ENST00000557181.1
ENST00000555839.1
ENST00000553368.1
ENST00000556054.1
ENST00000557054.1
ENST00000557592.1
ENST00000557150.1
APEX1
APEX nuclease (multifunctional DNA repair enzyme) 1
chr9_+_139221880 0.09 ENST00000392945.3
ENST00000440944.1
GPSM1
G-protein signaling modulator 1
chr17_+_9066252 0.08 ENST00000436734.1
NTN1
netrin 1
chr6_-_27440460 0.07 ENST00000377419.1
ZNF184
zinc finger protein 184
chr6_+_43265992 0.07 ENST00000449231.1
ENST00000372589.3
ENST00000372585.5
SLC22A7
solute carrier family 22 (organic anion transporter), member 7
chr1_+_28261533 0.07 ENST00000411604.1
ENST00000373888.4
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr13_-_41593425 0.07 ENST00000239882.3
ELF1
E74-like factor 1 (ets domain transcription factor)
chr1_-_155880672 0.07 ENST00000609492.1
ENST00000368322.3
RIT1
Ras-like without CAAX 1
chr12_+_55248289 0.07 ENST00000308796.6
MUCL1
mucin-like 1
chr7_+_30185406 0.07 ENST00000324489.5
C7orf41
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr14_+_24439148 0.07 ENST00000543805.1
ENST00000534993.1
DHRS4L2
dehydrogenase/reductase (SDR family) member 4 like 2
chr15_+_81293254 0.07 ENST00000267984.2
MESDC1
mesoderm development candidate 1
chr17_+_64961026 0.06 ENST00000262138.3
CACNG4
calcium channel, voltage-dependent, gamma subunit 4
chr2_-_127977654 0.06 ENST00000409327.1
CYP27C1
cytochrome P450, family 27, subfamily C, polypeptide 1
chr6_+_123038689 0.06 ENST00000354275.2
ENST00000368446.1
PKIB
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr1_-_1243252 0.06 ENST00000353662.3
ACAP3
ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
chr1_-_182642017 0.05 ENST00000367557.4
ENST00000258302.4
RGS8
regulator of G-protein signaling 8
chr16_+_6069072 0.05 ENST00000547605.1
ENST00000550418.1
ENST00000553186.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr1_-_167883327 0.05 ENST00000476818.2
ENST00000367851.4
ENST00000367848.1
ADCY10
adenylate cyclase 10 (soluble)
chr10_+_51187938 0.05 ENST00000311663.5
FAM21D
family with sequence similarity 21, member D
chrX_+_12993336 0.05 ENST00000380635.1
TMSB4X
thymosin beta 4, X-linked

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.2 GO:0035026 leading edge cell differentiation(GO:0035026)
0.9 3.7 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.9 2.7 GO:0035284 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.6 1.8 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.4 2.9 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.4 1.2 GO:0072709 cellular response to sorbitol(GO:0072709)
0.4 1.2 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.3 0.8 GO:1904772 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.2 1.2 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.2 2.2 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.2 0.7 GO:0018032 protein amidation(GO:0018032)
0.1 0.7 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.1 0.9 GO:0034670 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.1 0.4 GO:1900276 regulation of proteinase activated receptor activity(GO:1900276) negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900737)
0.1 0.8 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.4 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.1 0.6 GO:0030421 defecation(GO:0030421)
0.1 0.8 GO:1904424 regulation of GTP binding(GO:1904424)
0.1 0.3 GO:0003192 mitral valve formation(GO:0003192)
0.1 0.7 GO:0001661 conditioned taste aversion(GO:0001661)
0.1 0.4 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 0.3 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.2 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 1.1 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.1 1.5 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 2.3 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.7 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.5 GO:0075071 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.1 0.2 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.1 0.2 GO:0005988 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.1 0.2 GO:0003193 pulmonary valve formation(GO:0003193) visceral motor neuron differentiation(GO:0021524) foramen ovale closure(GO:0035922)
0.1 0.2 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 2.4 GO:0006536 glutamate metabolic process(GO:0006536)
0.0 0.1 GO:0048627 myoblast development(GO:0048627)
0.0 0.1 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 1.1 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 1.5 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.0 3.2 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.1 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.0 1.4 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.1 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0 0.4 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.1 GO:0044855 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.0 0.4 GO:0044351 macropinocytosis(GO:0044351)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.3 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.1 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.0 0.4 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.2 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 0.5 GO:0042226 interleukin-6 biosynthetic process(GO:0042226)
0.0 0.1 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.4 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.3 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.1 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.6 GO:0003416 endochondral bone growth(GO:0003416) bone growth(GO:0098868)
0.0 0.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.2 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.6 GO:0003016 respiratory system process(GO:0003016)
0.0 0.5 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.2 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0030091 protein repair(GO:0030091)
0.0 0.4 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.2 0.9 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.2 2.9 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 3.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 0.4 GO:0005607 laminin-2 complex(GO:0005607)
0.1 0.4 GO:0039713 viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517)
0.1 0.9 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.1 2.0 GO:0005687 U4 snRNP(GO:0005687)
0.1 0.4 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.1 0.7 GO:0035976 AP1 complex(GO:0035976)
0.1 2.2 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.8 GO:0000322 storage vacuole(GO:0000322)
0.0 0.8 GO:0045120 pronucleus(GO:0045120)
0.0 0.2 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.3 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.2 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.4 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.7 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 1.0 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0043219 lateral loop(GO:0043219)
0.0 3.0 GO:0030018 Z disc(GO:0030018)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 1.1 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.4 GO:0047820 D-glutamate cyclase activity(GO:0047820)
0.4 2.2 GO:0050436 microfibril binding(GO:0050436)
0.3 1.5 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.2 4.2 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.2 0.7 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.2 1.1 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 0.4 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 1.1 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1 3.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.9 GO:1990763 arrestin family protein binding(GO:1990763)
0.1 0.3 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.1 0.8 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1 0.5 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.1 0.3 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 1.9 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.4 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.2 GO:0004461 lactose synthase activity(GO:0004461)
0.0 3.2 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 3.0 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 1.1 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0 0.2 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.1 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.5 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.4 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.2 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.7 GO:0043015 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) gamma-tubulin binding(GO:0043015)
0.0 0.1 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.1 GO:0005503 all-trans retinal binding(GO:0005503)
0.0 0.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.4 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.2 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.9 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.1 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.1 GO:0097016 L27 domain binding(GO:0097016)
0.0 1.9 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.7 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.3 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0045159 myosin II binding(GO:0045159)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 2.0 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.6 PID FOXO PATHWAY FoxO family signaling
0.0 0.9 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 4.2 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 3.6 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 3.3 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 2.2 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.8 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.3 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 1.0 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.7 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.6 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.0 PID AR PATHWAY Coregulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 3.3 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 2.9 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 1.4 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 1.4 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.5 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 1.7 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.9 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 3.2 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 2.3 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 1.0 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1