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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for SOX5

Z-value: 1.74

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Transcription factors associated with SOX5

Gene Symbol Gene ID Gene Info
SOX5
ENSG00000134532.11 SRY-box transcription factor 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX5hg19_v2_chr12_-_24103954_241039720.611.1e-03Click!

Activity profile of SOX5 motif

Sorted Z-values of SOX5 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_41614909 9.94 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1
LIM and calponin homology domains 1
chr14_-_92414055 9.60 ENST00000342058.4
FBLN5
fibulin 5
chr3_-_18466026 9.51 ENST00000417717.2
SATB1
SATB homeobox 1
chr4_+_41614720 9.11 ENST00000509277.1
LIMCH1
LIM and calponin homology domains 1
chr2_-_188312971 8.92 ENST00000410068.1
ENST00000447403.1
ENST00000410102.1
CALCRL
calcitonin receptor-like
chr7_-_11871815 8.35 ENST00000423059.4
THSD7A
thrombospondin, type I, domain containing 7A
chr7_+_30960915 8.04 ENST00000441328.2
ENST00000409899.1
ENST00000409611.1
AQP1
aquaporin 1 (Colton blood group)
chr4_-_101439242 7.57 ENST00000296420.4
EMCN
endomucin
chr18_+_42260861 6.81 ENST00000282030.5
SETBP1
SET binding protein 1
chr10_+_35415719 6.73 ENST00000474362.1
ENST00000374721.3
CREM
cAMP responsive element modulator
chr20_-_45985172 6.62 ENST00000536340.1
ZMYND8
zinc finger, MYND-type containing 8
chr4_-_186732048 6.55 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
SORBS2
sorbin and SH3 domain containing 2
chrX_-_117107542 6.39 ENST00000371878.1
KLHL13
kelch-like family member 13
chr14_-_92413727 6.35 ENST00000267620.10
FBLN5
fibulin 5
chr4_-_101439148 6.04 ENST00000511970.1
ENST00000502569.1
ENST00000305864.3
EMCN
endomucin
chr2_-_157198860 5.78 ENST00000409572.1
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr1_+_61547405 5.73 ENST00000371189.4
NFIA
nuclear factor I/A
chr10_+_35416090 5.66 ENST00000354759.3
CREM
cAMP responsive element modulator
chr10_-_116444371 5.62 ENST00000533213.2
ENST00000369252.4
ABLIM1
actin binding LIM protein 1
chr8_-_93115445 5.53 ENST00000523629.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr10_+_35415978 5.49 ENST00000429130.3
ENST00000469949.2
ENST00000460270.1
CREM
cAMP responsive element modulator
chr14_-_92413353 5.11 ENST00000556154.1
FBLN5
fibulin 5
chr9_-_14314518 5.10 ENST00000397581.2
NFIB
nuclear factor I/B
chr9_-_14314566 5.06 ENST00000397579.2
NFIB
nuclear factor I/B
chr9_-_134145880 4.78 ENST00000372269.3
ENST00000464831.1
FAM78A
family with sequence similarity 78, member A
chr12_+_53443680 4.76 ENST00000314250.6
ENST00000451358.1
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr12_+_53443963 4.68 ENST00000546602.1
ENST00000552570.1
ENST00000549700.1
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr1_+_164528866 4.39 ENST00000420696.2
PBX1
pre-B-cell leukemia homeobox 1
chr10_+_35416223 4.11 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
CREM
cAMP responsive element modulator
chr2_-_160473114 4.10 ENST00000392783.2
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chrX_-_117107680 3.92 ENST00000447671.2
ENST00000262820.3
KLHL13
kelch-like family member 13
chr9_+_82188077 3.91 ENST00000425506.1
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr3_+_134514093 3.89 ENST00000398015.3
EPHB1
EPH receptor B1
chr12_+_32655048 3.82 ENST00000427716.2
ENST00000266482.3
FGD4
FYVE, RhoGEF and PH domain containing 4
chr14_+_61654271 3.80 ENST00000555185.1
ENST00000557294.1
ENST00000556778.1
PRKCH
protein kinase C, eta
chr1_+_185703513 3.43 ENST00000271588.4
ENST00000367492.2
HMCN1
hemicentin 1
chr20_-_45981138 3.41 ENST00000446994.2
ZMYND8
zinc finger, MYND-type containing 8
chr20_-_45985464 3.39 ENST00000458360.2
ENST00000262975.4
ZMYND8
zinc finger, MYND-type containing 8
chr20_-_45985414 3.36 ENST00000461685.1
ENST00000372023.3
ENST00000540497.1
ENST00000435836.1
ENST00000471951.2
ENST00000352431.2
ENST00000396281.4
ENST00000355972.4
ENST00000360911.3
ZMYND8
zinc finger, MYND-type containing 8
chr15_-_52944231 3.27 ENST00000546305.2
FAM214A
family with sequence similarity 214, member A
chr18_-_52989217 3.23 ENST00000570287.2
TCF4
transcription factor 4
chr9_-_124989804 3.18 ENST00000373755.2
ENST00000373754.2
LHX6
LIM homeobox 6
chr3_+_25469802 2.83 ENST00000330688.4
RARB
retinoic acid receptor, beta
chr14_-_89883412 2.74 ENST00000557258.1
FOXN3
forkhead box N3
chr1_+_33722080 2.74 ENST00000483388.1
ENST00000539719.1
ZNF362
zinc finger protein 362
chr14_+_77228532 2.73 ENST00000167106.4
ENST00000554237.1
VASH1
vasohibin 1
chr2_-_160472952 2.70 ENST00000541068.2
ENST00000355831.2
ENST00000343439.5
ENST00000392782.1
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chrX_+_135251783 2.66 ENST00000394153.2
FHL1
four and a half LIM domains 1
chr17_+_67498538 2.63 ENST00000589647.1
MAP2K6
mitogen-activated protein kinase kinase 6
chrX_+_135251835 2.39 ENST00000456445.1
FHL1
four and a half LIM domains 1
chr3_-_65583561 2.39 ENST00000460329.2
MAGI1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr3_-_141747439 2.35 ENST00000467667.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr9_-_126030817 2.33 ENST00000348403.5
ENST00000447404.2
ENST00000360998.3
STRBP
spermatid perinuclear RNA binding protein
chr18_-_53177984 2.27 ENST00000543082.1
TCF4
transcription factor 4
chr21_-_39870339 2.23 ENST00000429727.2
ENST00000398905.1
ENST00000398907.1
ENST00000453032.2
ENST00000288319.7
ERG
v-ets avian erythroblastosis virus E26 oncogene homolog
chr12_-_6233828 2.19 ENST00000572068.1
ENST00000261405.5
VWF
von Willebrand factor
chr12_+_52445191 2.13 ENST00000243050.1
ENST00000394825.1
ENST00000550763.1
ENST00000394824.2
ENST00000548232.1
ENST00000562373.1
NR4A1
nuclear receptor subfamily 4, group A, member 1
chr3_+_25469724 2.12 ENST00000437042.2
RARB
retinoic acid receptor, beta
chrX_+_135252050 2.09 ENST00000449474.1
ENST00000345434.3
FHL1
four and a half LIM domains 1
chr2_+_203499901 2.09 ENST00000303116.6
ENST00000392238.2
FAM117B
family with sequence similarity 117, member B
chr9_-_15510989 2.05 ENST00000380715.1
ENST00000380716.4
ENST00000380738.4
ENST00000380733.4
PSIP1
PC4 and SFRS1 interacting protein 1
chr20_-_45984401 2.04 ENST00000311275.7
ZMYND8
zinc finger, MYND-type containing 8
chr15_+_66994561 2.01 ENST00000288840.5
SMAD6
SMAD family member 6
chr12_-_71003568 2.00 ENST00000547715.1
ENST00000451516.2
ENST00000538708.1
ENST00000550857.1
ENST00000261266.5
PTPRB
protein tyrosine phosphatase, receptor type, B
chr9_-_72287191 1.98 ENST00000265381.4
APBA1
amyloid beta (A4) precursor protein-binding, family A, member 1
chr7_+_135611542 1.95 ENST00000416501.1
AC015987.2
AC015987.2
chr3_-_141747459 1.94 ENST00000477292.1
ENST00000478006.1
ENST00000495310.1
ENST00000486111.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr18_-_52989525 1.90 ENST00000457482.3
TCF4
transcription factor 4
chr7_-_32931623 1.88 ENST00000452926.1
KBTBD2
kelch repeat and BTB (POZ) domain containing 2
chr1_+_81771806 1.88 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2
latrophilin 2
chr5_+_138677515 1.84 ENST00000265192.4
ENST00000511706.1
PAIP2
poly(A) binding protein interacting protein 2
chr6_+_119215308 1.84 ENST00000229595.5
ASF1A
anti-silencing function 1A histone chaperone
chr1_+_163038565 1.83 ENST00000421743.2
RGS4
regulator of G-protein signaling 4
chr8_+_68864330 1.81 ENST00000288368.4
PREX2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr11_-_89224638 1.71 ENST00000535633.1
ENST00000263317.4
NOX4
NADPH oxidase 4
chr14_-_23904861 1.67 ENST00000355349.3
MYH7
myosin, heavy chain 7, cardiac muscle, beta
chrX_-_99891796 1.64 ENST00000373020.4
TSPAN6
tetraspanin 6
chr12_-_71031185 1.58 ENST00000548122.1
ENST00000551525.1
ENST00000550358.1
PTPRB
protein tyrosine phosphatase, receptor type, B
chr2_-_164592497 1.55 ENST00000333129.3
ENST00000409634.1
FIGN
fidgetin
chr10_+_63661053 1.53 ENST00000279873.7
ARID5B
AT rich interactive domain 5B (MRF1-like)
chr4_+_71588372 1.47 ENST00000536664.1
RUFY3
RUN and FYVE domain containing 3
chr6_+_155537771 1.47 ENST00000275246.7
TIAM2
T-cell lymphoma invasion and metastasis 2
chr2_-_70475701 1.45 ENST00000282574.4
TIA1
TIA1 cytotoxic granule-associated RNA binding protein
chr12_-_71031220 1.43 ENST00000334414.6
PTPRB
protein tyrosine phosphatase, receptor type, B
chr11_+_46402744 1.42 ENST00000533952.1
MDK
midkine (neurite growth-promoting factor 2)
chrX_+_107683096 1.37 ENST00000328300.6
ENST00000361603.2
COL4A5
collagen, type IV, alpha 5
chr3_+_141105705 1.37 ENST00000513258.1
ZBTB38
zinc finger and BTB domain containing 38
chr2_-_26205340 1.36 ENST00000264712.3
KIF3C
kinesin family member 3C
chr14_-_22005018 1.36 ENST00000546363.1
SALL2
spalt-like transcription factor 2
chr19_-_19626351 1.35 ENST00000585580.3
TSSK6
testis-specific serine kinase 6
chr4_+_170581213 1.35 ENST00000507875.1
CLCN3
chloride channel, voltage-sensitive 3
chr9_+_27109392 1.35 ENST00000406359.4
TEK
TEK tyrosine kinase, endothelial
chr12_+_56360605 1.34 ENST00000553376.1
ENST00000440311.2
ENST00000354056.4
CDK2
cyclin-dependent kinase 2
chr1_+_150337144 1.33 ENST00000539519.1
ENST00000369067.3
ENST00000369068.4
RPRD2
regulation of nuclear pre-mRNA domain containing 2
chr6_-_79944336 1.30 ENST00000344726.5
ENST00000275036.7
HMGN3
high mobility group nucleosomal binding domain 3
chr12_+_60058458 1.27 ENST00000548610.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chrX_-_100872911 1.27 ENST00000361910.4
ENST00000539247.1
ENST00000538627.1
ARMCX6
armadillo repeat containing, X-linked 6
chr1_-_53018654 1.27 ENST00000257177.4
ENST00000355809.4
ENST00000528642.1
ENST00000470626.1
ENST00000371544.3
ZCCHC11
zinc finger, CCHC domain containing 11
chr6_+_89790459 1.27 ENST00000369472.1
PNRC1
proline-rich nuclear receptor coactivator 1
chr10_-_14646388 1.25 ENST00000468747.1
ENST00000378467.4
FAM107B
family with sequence similarity 107, member B
chr2_-_70475730 1.24 ENST00000445587.1
ENST00000433529.2
ENST00000415783.2
TIA1
TIA1 cytotoxic granule-associated RNA binding protein
chr11_-_82708519 1.24 ENST00000534301.1
RAB30
RAB30, member RAS oncogene family
chr12_-_102591604 1.22 ENST00000329406.4
PMCH
pro-melanin-concentrating hormone
chr3_-_48754599 1.21 ENST00000413654.1
ENST00000454335.1
ENST00000440424.1
ENST00000449610.1
ENST00000443964.1
ENST00000417896.1
ENST00000413298.1
ENST00000449563.1
ENST00000443853.1
ENST00000437427.1
ENST00000446860.1
ENST00000412850.1
ENST00000424035.1
ENST00000340879.4
ENST00000431721.2
ENST00000434860.1
ENST00000328631.5
ENST00000432678.2
IP6K2
inositol hexakisphosphate kinase 2
chr13_+_103459704 1.20 ENST00000602836.1
BIVM-ERCC5
BIVM-ERCC5 readthrough
chr11_+_46402583 1.20 ENST00000359803.3
MDK
midkine (neurite growth-promoting factor 2)
chr2_-_192711968 1.19 ENST00000304141.4
SDPR
serum deprivation response
chr13_-_74708372 1.17 ENST00000377666.4
KLF12
Kruppel-like factor 12
chr10_+_99079008 1.16 ENST00000371021.3
FRAT1
frequently rearranged in advanced T-cell lymphomas
chr6_+_122720681 1.14 ENST00000368455.4
ENST00000452194.1
HSF2
heat shock transcription factor 2
chr3_-_114343039 1.08 ENST00000481632.1
ZBTB20
zinc finger and BTB domain containing 20
chr6_+_43027595 1.06 ENST00000259708.3
ENST00000472792.1
ENST00000479388.1
ENST00000460283.1
ENST00000394056.2
KLC4
kinesin light chain 4
chr5_+_138678131 1.06 ENST00000394795.2
ENST00000510080.1
PAIP2
poly(A) binding protein interacting protein 2
chr3_-_69129501 1.05 ENST00000540295.1
ENST00000415609.2
ENST00000361055.4
ENST00000349511.4
UBA3
ubiquitin-like modifier activating enzyme 3
chr3_+_141106458 1.02 ENST00000509883.1
ZBTB38
zinc finger and BTB domain containing 38
chr7_-_27205136 1.02 ENST00000396345.1
ENST00000343483.6
HOXA9
homeobox A9
chr6_+_35996859 1.02 ENST00000472333.1
MAPK14
mitogen-activated protein kinase 14
chrX_-_64196376 1.00 ENST00000447788.2
ZC4H2
zinc finger, C4H2 domain containing
chr6_+_89790490 0.97 ENST00000336032.3
PNRC1
proline-rich nuclear receptor coactivator 1
chr12_+_56360550 0.97 ENST00000266970.4
CDK2
cyclin-dependent kinase 2
chr1_+_15272271 0.96 ENST00000400797.3
KAZN
kazrin, periplakin interacting protein
chr12_-_102874330 0.95 ENST00000307046.8
IGF1
insulin-like growth factor 1 (somatomedin C)
chrX_-_50557014 0.94 ENST00000376020.2
SHROOM4
shroom family member 4
chr9_-_123476612 0.92 ENST00000426959.1
MEGF9
multiple EGF-like-domains 9
chr4_+_110749143 0.92 ENST00000317735.4
RRH
retinal pigment epithelium-derived rhodopsin homolog
chr10_+_97803151 0.92 ENST00000403870.3
ENST00000265992.5
ENST00000465148.2
ENST00000534974.1
CCNJ
cyclin J
chr9_-_123476719 0.92 ENST00000373930.3
MEGF9
multiple EGF-like-domains 9
chr2_+_33661382 0.91 ENST00000402538.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr1_+_150337100 0.91 ENST00000401000.4
RPRD2
regulation of nuclear pre-mRNA domain containing 2
chr5_-_38595498 0.91 ENST00000263409.4
LIFR
leukemia inhibitory factor receptor alpha
chr1_+_205682497 0.90 ENST00000598338.1
AC119673.1
AC119673.1
chrX_-_112084043 0.90 ENST00000304758.1
AMOT
angiomotin
chr11_+_46402482 0.89 ENST00000441869.1
MDK
midkine (neurite growth-promoting factor 2)
chr16_+_1128781 0.88 ENST00000293897.4
ENST00000562758.1
SSTR5
somatostatin receptor 5
chr6_-_99873145 0.87 ENST00000369239.5
ENST00000438806.1
PNISR
PNN-interacting serine/arginine-rich protein
chrX_-_24690771 0.87 ENST00000379145.1
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr1_-_86043921 0.85 ENST00000535924.2
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr1_+_228337553 0.76 ENST00000366714.2
GJC2
gap junction protein, gamma 2, 47kDa
chrX_+_123094672 0.76 ENST00000354548.5
ENST00000458700.1
STAG2
stromal antigen 2
chr11_-_102323489 0.74 ENST00000361236.3
TMEM123
transmembrane protein 123
chr3_+_189507460 0.74 ENST00000434928.1
TP63
tumor protein p63
chrX_+_123094369 0.72 ENST00000455404.1
ENST00000218089.9
STAG2
stromal antigen 2
chr16_+_3704822 0.71 ENST00000414110.2
DNASE1
deoxyribonuclease I
chr7_+_77167343 0.70 ENST00000433369.2
ENST00000415482.2
PTPN12
protein tyrosine phosphatase, non-receptor type 12
chr3_-_114790179 0.65 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr12_-_102874102 0.65 ENST00000392905.2
IGF1
insulin-like growth factor 1 (somatomedin C)
chr17_+_37894570 0.65 ENST00000394211.3
GRB7
growth factor receptor-bound protein 7
chr1_-_151119087 0.63 ENST00000341697.3
ENST00000368914.3
SEMA6C
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
chr20_+_32150140 0.62 ENST00000344201.3
ENST00000346541.3
ENST00000397800.1
ENST00000397798.2
ENST00000492345.1
CBFA2T2
core-binding factor, runt domain, alpha subunit 2; translocated to, 2
chr4_-_2264015 0.62 ENST00000337190.2
MXD4
MAX dimerization protein 4
chr11_-_102323740 0.62 ENST00000398136.2
TMEM123
transmembrane protein 123
chr9_+_27109133 0.60 ENST00000519097.1
ENST00000380036.4
TEK
TEK tyrosine kinase, endothelial
chr12_-_8815477 0.60 ENST00000433590.2
MFAP5
microfibrillar associated protein 5
chr7_-_32931387 0.60 ENST00000304056.4
KBTBD2
kelch repeat and BTB (POZ) domain containing 2
chrX_+_70503037 0.58 ENST00000535149.1
NONO
non-POU domain containing, octamer-binding
chr18_+_3451646 0.58 ENST00000345133.5
ENST00000330513.5
ENST00000549546.1
TGIF1
TGFB-induced factor homeobox 1
chr1_-_21503337 0.58 ENST00000400422.1
ENST00000602326.1
ENST00000411888.1
ENST00000438975.1
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr18_+_3451584 0.57 ENST00000551541.1
TGIF1
TGFB-induced factor homeobox 1
chr20_-_3762087 0.57 ENST00000379756.3
SPEF1
sperm flagellar 1
chr17_-_4269920 0.56 ENST00000572484.1
UBE2G1
ubiquitin-conjugating enzyme E2G 1
chr1_-_150241341 0.56 ENST00000369109.3
ENST00000414276.2
ENST00000236017.5
APH1A
APH1A gamma secretase subunit
chrX_+_130192318 0.56 ENST00000370922.1
ARHGAP36
Rho GTPase activating protein 36
chr11_+_128563948 0.55 ENST00000534087.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr2_-_200323414 0.55 ENST00000443023.1
SATB2
SATB homeobox 2
chr6_+_43027332 0.53 ENST00000347162.5
ENST00000453940.2
ENST00000479632.1
ENST00000470728.1
ENST00000458460.2
KLC4
kinesin light chain 4
chr20_-_61002584 0.51 ENST00000252998.1
RBBP8NL
RBBP8 N-terminal like
chr1_+_153232160 0.50 ENST00000368742.3
LOR
loricrin
chr11_-_82708435 0.50 ENST00000525117.1
ENST00000532548.1
RAB30
RAB30, member RAS oncogene family
chr10_-_32667660 0.50 ENST00000375110.2
EPC1
enhancer of polycomb homolog 1 (Drosophila)
chr12_-_111926342 0.46 ENST00000389154.3
ATXN2
ataxin 2
chr20_+_17207665 0.44 ENST00000536609.1
PCSK2
proprotein convertase subtilisin/kexin type 2
chr1_+_29241027 0.43 ENST00000373797.1
EPB41
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr1_+_164529004 0.42 ENST00000559240.1
ENST00000367897.1
ENST00000540236.1
ENST00000401534.1
PBX1
pre-B-cell leukemia homeobox 1
chr7_+_111846741 0.42 ENST00000421043.1
ENST00000425229.1
ENST00000450657.1
ZNF277
zinc finger protein 277
chr14_-_91884115 0.42 ENST00000389857.6
CCDC88C
coiled-coil domain containing 88C
chr1_-_156217822 0.41 ENST00000368270.1
PAQR6
progestin and adipoQ receptor family member VI
chr14_-_51027838 0.41 ENST00000555216.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chrX_-_106959631 0.40 ENST00000486554.1
ENST00000372390.4
TSC22D3
TSC22 domain family, member 3
chr3_-_129407535 0.39 ENST00000432054.2
TMCC1
transmembrane and coiled-coil domain family 1
chr16_+_2083265 0.39 ENST00000565855.1
ENST00000566198.1
SLC9A3R2
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
chrX_-_50557302 0.39 ENST00000289292.7
SHROOM4
shroom family member 4
chr8_+_103563792 0.39 ENST00000285402.3
ODF1
outer dense fiber of sperm tails 1
chr22_+_38093005 0.39 ENST00000406386.3
TRIOBP
TRIO and F-actin binding protein
chr13_+_28813645 0.38 ENST00000282391.5
PAN3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr5_-_134871639 0.36 ENST00000314744.4
NEUROG1
neurogenin 1
chr1_-_156217829 0.36 ENST00000356983.2
ENST00000335852.1
ENST00000340183.5
ENST00000540423.1
PAQR6
progestin and adipoQ receptor family member VI
chr10_+_49514698 0.35 ENST00000432379.1
ENST00000429041.1
ENST00000374189.1
MAPK8
mitogen-activated protein kinase 8
chr21_+_35552978 0.35 ENST00000428914.2
ENST00000609062.1
ENST00000609947.1
LINC00310
long intergenic non-protein coding RNA 310
chr1_-_193155729 0.35 ENST00000367434.4
B3GALT2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr1_-_156217875 0.33 ENST00000292291.5
PAQR6
progestin and adipoQ receptor family member VI
chr3_+_120315160 0.31 ENST00000485064.1
ENST00000492739.1
NDUFB4
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa
chr17_+_37894179 0.31 ENST00000577695.1
ENST00000309156.4
ENST00000309185.3
GRB7
growth factor receptor-bound protein 7
chr15_-_37391507 0.31 ENST00000557796.2
ENST00000397620.2
MEIS2
Meis homeobox 2
chr19_-_19626838 0.30 ENST00000360913.3
TSSK6
testis-specific serine kinase 6
chrX_-_17878827 0.29 ENST00000360011.1
RAI2
retinoic acid induced 2
chr10_-_13523073 0.29 ENST00000440282.1
BEND7
BEN domain containing 7
chr9_-_69229650 0.29 ENST00000416428.1
CBWD6
COBW domain containing 6
chr12_-_8815404 0.29 ENST00000359478.2
ENST00000396549.2
MFAP5
microfibrillar associated protein 5
chr12_-_12674032 0.29 ENST00000298573.4
DUSP16
dual specificity phosphatase 16
chr9_+_132099158 0.29 ENST00000444125.1
RP11-65J3.1
RP11-65J3.1

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 18.8 GO:1903758 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
2.7 8.0 GO:0035378 carbon dioxide transmembrane transport(GO:0035378) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
1.9 5.8 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
1.6 21.1 GO:0048251 elastic fiber assembly(GO:0048251)
1.5 10.2 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
1.3 3.9 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.9 2.7 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.9 2.6 GO:0072709 cellular response to sorbitol(GO:0072709)
0.8 8.9 GO:0009744 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.6 3.5 GO:0030421 defecation(GO:0030421)
0.5 9.5 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.5 5.0 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.4 1.7 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
0.4 3.8 GO:0034351 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.4 2.2 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.4 0.4 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.4 1.1 GO:0007113 endomitotic cell cycle(GO:0007113)
0.3 2.1 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.3 2.0 GO:0048014 Tie signaling pathway(GO:0048014)
0.3 17.7 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.3 5.7 GO:0072189 ureter development(GO:0072189)
0.3 2.3 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.2 2.2 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.2 3.2 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.2 0.2 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.2 2.9 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.2 2.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.2 1.3 GO:0048388 endosomal lumen acidification(GO:0048388)
0.2 7.4 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.2 1.0 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.2 2.2 GO:0003183 mitral valve morphogenesis(GO:0003183)
0.2 0.9 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.2 0.9 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.2 1.8 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.2 4.8 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.2 1.3 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.2 2.0 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.1 3.1 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.1 1.5 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.1 1.6 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.1 0.6 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.1 0.6 GO:0030070 insulin processing(GO:0030070)
0.1 1.7 GO:0035092 sperm chromatin condensation(GO:0035092)
0.1 5.4 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.1 1.4 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 7.0 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.1 2.9 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.1 1.4 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1 4.3 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 2.3 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.1 0.6 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 0.3 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.1 0.4 GO:0030047 actin modification(GO:0030047)
0.1 0.2 GO:1904247 regulation of polynucleotide adenylyltransferase activity(GO:1904245) positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.1 0.2 GO:0097155 fasciculation of sensory neuron axon(GO:0097155) fasciculation of motor neuron axon(GO:0097156)
0.1 0.9 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 0.5 GO:0035886 vascular smooth muscle cell differentiation(GO:0035886)
0.1 1.7 GO:0007638 mechanosensory behavior(GO:0007638)
0.1 0.2 GO:0060721 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.1 3.8 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.1 1.5 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.1 0.8 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.1 0.9 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.1 0.3 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 5.6 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 0.8 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.1 1.3 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.1 0.2 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1 17.6 GO:0031032 actomyosin structure organization(GO:0031032)
0.1 0.3 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.9 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 1.2 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.4 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.1 GO:0035284 rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 1.8 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.5 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 1.8 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.3 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.4 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 7.5 GO:0000910 cytokinesis(GO:0000910)
0.0 0.5 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0 1.0 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 1.7 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.1 GO:0021722 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.0 0.2 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.0 0.2 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 1.5 GO:0042795 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.6 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.5 GO:0035855 megakaryocyte development(GO:0035855)
0.0 1.0 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 0.1 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.9 GO:0006817 phosphate ion transport(GO:0006817)
0.0 1.4 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 1.5 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.5 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.0 5.9 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 12.4 GO:0001525 angiogenesis(GO:0001525)
0.0 1.5 GO:0045638 negative regulation of myeloid cell differentiation(GO:0045638)
0.0 3.2 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.9 GO:0097435 fibril organization(GO:0097435)
0.0 0.1 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.2 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0 0.6 GO:2000772 regulation of cellular senescence(GO:2000772)
0.0 0.8 GO:0010644 cell communication by electrical coupling(GO:0010644)
0.0 1.0 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.7 GO:0006308 DNA catabolic process(GO:0006308)
0.0 0.4 GO:0031648 protein destabilization(GO:0031648)
0.0 2.5 GO:0006275 regulation of DNA replication(GO:0006275)
0.0 0.3 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.2 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.0 1.2 GO:0007631 feeding behavior(GO:0007631)
0.0 1.4 GO:0021915 neural tube development(GO:0021915)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 8.0 GO:0020005 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
2.1 21.1 GO:0071953 elastic fiber(GO:0071953)
0.8 2.3 GO:0097134 Y chromosome(GO:0000806) cyclin A2-CDK2 complex(GO:0097124) cyclin E1-CDK2 complex(GO:0097134)
0.6 10.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.4 2.9 GO:0097165 nuclear stress granule(GO:0097165)
0.2 17.2 GO:0043198 dendritic shaft(GO:0043198)
0.2 9.5 GO:0005720 nuclear heterochromatin(GO:0005720)
0.2 1.4 GO:0005587 collagen type IV trimer(GO:0005587)
0.2 2.2 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 12.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 0.5 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.1 0.8 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.1 0.4 GO:0031251 PAN complex(GO:0031251)
0.1 1.7 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.5 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 2.1 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 34.5 GO:0005667 transcription factor complex(GO:0005667)
0.1 0.6 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 0.9 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 1.5 GO:0071437 invadopodium(GO:0071437)
0.0 7.1 GO:0016363 nuclear matrix(GO:0016363)
0.0 5.0 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.9 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 1.2 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 4.9 GO:0005604 basement membrane(GO:0005604)
0.0 2.2 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0 0.8 GO:0005922 connexon complex(GO:0005922)
0.0 0.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.4 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.2 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 1.0 GO:0030057 desmosome(GO:0030057)
0.0 0.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 1.3 GO:0031941 filamentous actin(GO:0031941)
0.0 5.3 GO:0030018 Z disc(GO:0030018)
0.0 2.0 GO:0005871 kinesin complex(GO:0005871)
0.0 0.8 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 1.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 3.0 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 2.4 GO:0031901 early endosome membrane(GO:0031901)
0.0 7.1 GO:0016607 nuclear speck(GO:0016607)
0.0 0.5 GO:0001533 cornified envelope(GO:0001533)
0.0 2.5 GO:0072562 blood microparticle(GO:0072562)
0.0 1.5 GO:0031985 Golgi cisterna(GO:0031985)
0.0 4.4 GO:0000785 chromatin(GO:0000785)
0.0 3.9 GO:0016604 nuclear body(GO:0016604)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 8.0 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
2.2 8.9 GO:0004948 calcitonin receptor activity(GO:0004948)
1.2 21.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.8 3.8 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.7 2.2 GO:0070698 type I activin receptor binding(GO:0070698)
0.6 7.4 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.5 3.9 GO:0008046 axon guidance receptor activity(GO:0008046)
0.5 18.8 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.3 10.7 GO:0046965 retinoid X receptor binding(GO:0046965)
0.3 1.3 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.3 1.3 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.3 0.9 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.3 1.2 GO:0052836 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.2 6.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 1.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.2 0.4 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2 0.7 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.2 0.9 GO:0004994 somatostatin receptor activity(GO:0004994)
0.2 0.9 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.2 2.1 GO:0097100 supercoiled DNA binding(GO:0097100)
0.2 0.9 GO:0043532 angiostatin binding(GO:0043532)
0.1 3.9 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 1.1 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1 1.7 GO:0019826 oxygen sensor activity(GO:0019826)
0.1 0.8 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 24.0 GO:0005178 integrin binding(GO:0005178)
0.1 0.4 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1 1.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 0.8 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.1 2.9 GO:0008143 poly(A) binding(GO:0008143)
0.1 2.3 GO:0035173 histone kinase activity(GO:0035173)
0.1 0.9 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 2.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 1.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 1.8 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 2.4 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 2.2 GO:0030371 translation repressor activity(GO:0030371)
0.0 3.9 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.4 GO:0043426 MRF binding(GO:0043426)
0.0 0.5 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 1.2 GO:0070410 co-SMAD binding(GO:0070410)
0.0 19.3 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 1.3 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 10.2 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 4.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.6 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.5 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.1 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.0 0.6 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.6 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 2.3 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 2.2 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.4 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 2.0 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 4.2 GO:0044325 ion channel binding(GO:0044325)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 2.0 GO:0003777 microtubule motor activity(GO:0003777)
0.0 3.9 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.6 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 9.3 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 2.4 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0051787 misfolded protein binding(GO:0051787)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 20.8 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.2 15.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 2.6 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 5.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 1.5 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 26.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 9.5 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 9.5 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 3.5 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 1.4 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 1.4 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 3.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 3.8 PID ENDOTHELIN PATHWAY Endothelins
0.0 2.1 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 4.1 PID E2F PATHWAY E2F transcription factor network
0.0 10.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 4.0 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.7 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.8 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 4.1 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 2.4 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.6 PID BMP PATHWAY BMP receptor signaling
0.0 1.5 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.6 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.9 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.4 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.6 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.2 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 8.0 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.3 10.2 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.2 2.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.2 10.2 REACTOME MYOGENESIS Genes involved in Myogenesis
0.2 5.6 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.2 2.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 9.7 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 3.8 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 2.9 REACTOME KINESINS Genes involved in Kinesins
0.1 1.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 6.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 8.8 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 2.1 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 0.9 REACTOME OPSINS Genes involved in Opsins
0.1 1.8 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 4.4 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 2.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 1.2 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 3.2 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.6 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 10.8 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.9 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 1.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.8 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.3 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.5 REACTOME SIGNALING BY WNT Genes involved in Signaling by Wnt
0.0 0.9 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 1.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.6 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.5 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 1.2 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 2.1 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.1 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.2 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs