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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for SOX6

Z-value: 0.50

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Transcription factors associated with SOX6

Gene Symbol Gene ID Gene Info
SOX6
ENSG00000110693.11 SRY-box transcription factor 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX6hg19_v2_chr11_-_16430399_164304400.135.3e-01Click!

Activity profile of SOX6 motif

Sorted Z-values of SOX6 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_208031542 1.24 ENST00000423015.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr4_+_41614720 1.19 ENST00000509277.1
LIMCH1
LIM and calponin homology domains 1
chr4_+_41614909 1.16 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1
LIM and calponin homology domains 1
chr14_-_51027838 1.12 ENST00000555216.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr11_-_10830463 0.97 ENST00000527419.1
ENST00000530211.1
ENST00000530702.1
ENST00000524932.1
ENST00000532570.1
EIF4G2
eukaryotic translation initiation factor 4 gamma, 2
chr14_+_103589789 0.80 ENST00000558056.1
ENST00000560869.1
TNFAIP2
tumor necrosis factor, alpha-induced protein 2
chr6_+_126240442 0.62 ENST00000448104.1
ENST00000438495.1
ENST00000444128.1
NCOA7
nuclear receptor coactivator 7
chr20_+_6748311 0.61 ENST00000378827.4
BMP2
bone morphogenetic protein 2
chr2_-_37899323 0.55 ENST00000295324.3
ENST00000457889.1
CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr1_+_182808474 0.55 ENST00000367549.3
DHX9
DEAH (Asp-Glu-Ala-His) box helicase 9
chrX_-_117107542 0.50 ENST00000371878.1
KLHL13
kelch-like family member 13
chr18_+_6729698 0.50 ENST00000383472.4
ARHGAP28
Rho GTPase activating protein 28
chr10_+_35416223 0.50 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
CREM
cAMP responsive element modulator
chr14_+_22748980 0.44 ENST00000390465.2
TRAV38-2DV8
T cell receptor alpha variable 38-2/delta variable 8
chr22_-_27014043 0.43 ENST00000215939.2
CRYBB1
crystallin, beta B1
chr8_-_6420777 0.43 ENST00000415216.1
ANGPT2
angiopoietin 2
chr4_+_144303093 0.41 ENST00000505913.1
GAB1
GRB2-associated binding protein 1
chr7_+_77167343 0.38 ENST00000433369.2
ENST00000415482.2
PTPN12
protein tyrosine phosphatase, non-receptor type 12
chr11_+_128563948 0.38 ENST00000534087.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr2_+_111880242 0.37 ENST00000393252.3
BCL2L11
BCL2-like 11 (apoptosis facilitator)
chr21_+_33784670 0.37 ENST00000300255.2
EVA1C
eva-1 homolog C (C. elegans)
chr14_-_35344093 0.36 ENST00000382422.2
BAZ1A
bromodomain adjacent to zinc finger domain, 1A
chr11_+_128563652 0.35 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr6_+_132455118 0.33 ENST00000458028.1
LINC01013
long intergenic non-protein coding RNA 1013
chr17_-_18585131 0.33 ENST00000443457.1
ENST00000583002.1
ZNF286B
zinc finger protein 286B
chr9_-_74979420 0.33 ENST00000343431.2
ENST00000376956.3
ZFAND5
zinc finger, AN1-type domain 5
chr9_-_123476719 0.33 ENST00000373930.3
MEGF9
multiple EGF-like-domains 9
chr1_+_228337553 0.32 ENST00000366714.2
GJC2
gap junction protein, gamma 2, 47kDa
chr17_-_76719807 0.30 ENST00000589297.1
CYTH1
cytohesin 1
chr6_-_75915757 0.30 ENST00000322507.8
COL12A1
collagen, type XII, alpha 1
chr5_+_140749803 0.30 ENST00000576222.1
PCDHGB3
protocadherin gamma subfamily B, 3
chrX_+_84499081 0.29 ENST00000276123.3
ZNF711
zinc finger protein 711
chr17_-_76713100 0.28 ENST00000585509.1
CYTH1
cytohesin 1
chr16_+_30406721 0.28 ENST00000320159.2
ZNF48
zinc finger protein 48
chr15_-_82338460 0.28 ENST00000558133.1
ENST00000329713.4
MEX3B
mex-3 RNA binding family member B
chrX_-_45060135 0.27 ENST00000398000.2
ENST00000377934.4
CXorf36
chromosome X open reading frame 36
chr15_-_73075964 0.27 ENST00000563907.1
ADPGK
ADP-dependent glucokinase
chr4_+_55524085 0.26 ENST00000412167.2
ENST00000288135.5
KIT
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
chr10_-_25241499 0.26 ENST00000376378.1
ENST00000376376.3
ENST00000320152.6
PRTFDC1
phosphoribosyl transferase domain containing 1
chr15_+_81293254 0.25 ENST00000267984.2
MESDC1
mesoderm development candidate 1
chr12_-_109219937 0.25 ENST00000546697.1
SSH1
slingshot protein phosphatase 1
chr15_+_63335899 0.24 ENST00000561266.1
TPM1
tropomyosin 1 (alpha)
chr4_+_54243917 0.24 ENST00000507166.1
FIP1L1
factor interacting with PAPOLA and CPSF1
chr15_+_85923797 0.24 ENST00000559362.1
AKAP13
A kinase (PRKA) anchor protein 13
chr15_+_52311398 0.23 ENST00000261845.5
MAPK6
mitogen-activated protein kinase 6
chr17_-_40288449 0.23 ENST00000552162.1
ENST00000550504.1
RAB5C
RAB5C, member RAS oncogene family
chr2_-_231989808 0.23 ENST00000258400.3
HTR2B
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chr12_+_69979446 0.23 ENST00000543146.2
CCT2
chaperonin containing TCP1, subunit 2 (beta)
chr2_+_10262857 0.23 ENST00000304567.5
RRM2
ribonucleotide reductase M2
chr14_+_23791159 0.22 ENST00000557702.1
PABPN1
poly(A) binding protein, nuclear 1
chr6_+_132455526 0.22 ENST00000443303.1
LINC01013
long intergenic non-protein coding RNA 1013
chr3_-_65583561 0.22 ENST00000460329.2
MAGI1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr13_+_24144796 0.21 ENST00000403372.2
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr7_-_128415844 0.21 ENST00000249389.2
OPN1SW
opsin 1 (cone pigments), short-wave-sensitive
chr1_-_182360498 0.21 ENST00000417584.2
GLUL
glutamate-ammonia ligase
chr19_+_47105309 0.21 ENST00000599839.1
ENST00000596362.1
CALM3
calmodulin 3 (phosphorylase kinase, delta)
chrX_+_70503433 0.21 ENST00000276079.8
ENST00000373856.3
ENST00000373841.1
ENST00000420903.1
NONO
non-POU domain containing, octamer-binding
chr11_-_69519410 0.21 ENST00000294312.3
FGF19
fibroblast growth factor 19
chr9_+_139874683 0.21 ENST00000444903.1
PTGDS
prostaglandin D2 synthase 21kDa (brain)
chr16_+_23765948 0.21 ENST00000300113.2
CHP2
calcineurin-like EF-hand protein 2
chr5_-_180018540 0.20 ENST00000292641.3
SCGB3A1
secretoglobin, family 3A, member 1
chr4_-_146101304 0.20 ENST00000447906.2
OTUD4
OTU domain containing 4
chr12_+_93096619 0.20 ENST00000397833.3
C12orf74
chromosome 12 open reading frame 74
chr1_+_24286287 0.20 ENST00000334351.7
ENST00000374468.1
PNRC2
proline-rich nuclear receptor coactivator 2
chr5_-_146435694 0.20 ENST00000356826.3
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr2_-_158182410 0.19 ENST00000419116.2
ENST00000410096.1
ERMN
ermin, ERM-like protein
chr12_+_93096759 0.19 ENST00000544406.2
C12orf74
chromosome 12 open reading frame 74
chr10_+_114043493 0.19 ENST00000369422.3
TECTB
tectorin beta
chr18_-_52989217 0.19 ENST00000570287.2
TCF4
transcription factor 4
chr12_-_88974236 0.19 ENST00000228280.5
ENST00000552044.1
ENST00000357116.4
KITLG
KIT ligand
chr15_+_74610894 0.18 ENST00000558821.1
ENST00000268082.4
CCDC33
coiled-coil domain containing 33
chr8_+_107738343 0.18 ENST00000521592.1
OXR1
oxidation resistance 1
chr3_-_197024394 0.18 ENST00000434148.1
ENST00000412364.2
ENST00000436682.1
ENST00000456699.2
ENST00000392380.2
DLG1
discs, large homolog 1 (Drosophila)
chr5_-_146435572 0.18 ENST00000394414.1
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr5_-_146435501 0.18 ENST00000336640.6
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr12_-_71003568 0.18 ENST00000547715.1
ENST00000451516.2
ENST00000538708.1
ENST00000550857.1
ENST00000261266.5
PTPRB
protein tyrosine phosphatase, receptor type, B
chr14_-_71107921 0.17 ENST00000553982.1
ENST00000500016.1
CTD-2540L5.5
CTD-2540L5.6
CTD-2540L5.5
CTD-2540L5.6
chr1_-_201476274 0.17 ENST00000340006.2
CSRP1
cysteine and glycine-rich protein 1
chr2_+_170590321 0.17 ENST00000392647.2
KLHL23
kelch-like family member 23
chr4_+_71570430 0.17 ENST00000417478.2
RUFY3
RUN and FYVE domain containing 3
chr11_+_34654011 0.17 ENST00000531794.1
EHF
ets homologous factor
chrX_+_135579238 0.17 ENST00000535601.1
ENST00000448450.1
ENST00000425695.1
HTATSF1
HIV-1 Tat specific factor 1
chrX_+_84498989 0.17 ENST00000395402.1
ZNF711
zinc finger protein 711
chr10_+_35415851 0.16 ENST00000374726.3
CREM
cAMP responsive element modulator
chr5_-_16936340 0.16 ENST00000507288.1
ENST00000513610.1
MYO10
myosin X
chr7_-_19813192 0.16 ENST00000422233.1
ENST00000433641.1
TMEM196
transmembrane protein 196
chr4_+_26585538 0.16 ENST00000264866.4
TBC1D19
TBC1 domain family, member 19
chr19_+_5681011 0.16 ENST00000581893.1
ENST00000411793.2
ENST00000301382.4
ENST00000581773.1
ENST00000423665.2
ENST00000583928.1
ENST00000342970.2
ENST00000422535.2
ENST00000581521.1
ENST00000339423.2
HSD11B1L
hydroxysteroid (11-beta) dehydrogenase 1-like
chr16_-_31085033 0.16 ENST00000414399.1
ZNF668
zinc finger protein 668
chr8_-_141810634 0.16 ENST00000521986.1
ENST00000523539.1
ENST00000538769.1
PTK2
protein tyrosine kinase 2
chr6_-_107436473 0.16 ENST00000369042.1
BEND3
BEN domain containing 3
chr9_-_39239171 0.16 ENST00000358144.2
CNTNAP3
contactin associated protein-like 3
chr18_+_6729725 0.16 ENST00000400091.2
ENST00000583410.1
ENST00000584387.1
ARHGAP28
Rho GTPase activating protein 28
chr11_-_76155618 0.16 ENST00000530759.1
RP11-111M22.3
RP11-111M22.3
chr7_+_116312411 0.16 ENST00000456159.1
ENST00000397752.3
ENST00000318493.6
MET
met proto-oncogene
chr17_-_14683517 0.15 ENST00000379640.1
AC005863.1
AC005863.1
chrX_+_84499038 0.15 ENST00000373165.3
ZNF711
zinc finger protein 711
chr7_-_99699538 0.15 ENST00000343023.6
ENST00000303887.5
MCM7
minichromosome maintenance complex component 7
chr17_+_36584662 0.15 ENST00000431231.2
ENST00000437668.3
ARHGAP23
Rho GTPase activating protein 23
chr12_+_100041527 0.15 ENST00000324341.1
FAM71C
family with sequence similarity 71, member C
chr12_+_104359576 0.15 ENST00000392872.3
ENST00000436021.2
TDG
thymine-DNA glycosylase
chr6_-_89927151 0.14 ENST00000454853.2
GABRR1
gamma-aminobutyric acid (GABA) A receptor, rho 1
chr11_-_82708435 0.14 ENST00000525117.1
ENST00000532548.1
RAB30
RAB30, member RAS oncogene family
chr9_+_124103625 0.14 ENST00000594963.1
AL161784.1
Uncharacterized protein
chr7_+_29234101 0.14 ENST00000435288.2
CHN2
chimerin 2
chr7_+_29234028 0.14 ENST00000222792.6
CHN2
chimerin 2
chrX_+_80457442 0.14 ENST00000373212.5
SH3BGRL
SH3 domain binding glutamic acid-rich protein like
chr11_-_82708519 0.14 ENST00000534301.1
RAB30
RAB30, member RAS oncogene family
chr16_+_2083265 0.14 ENST00000565855.1
ENST00000566198.1
SLC9A3R2
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
chr1_-_201123546 0.13 ENST00000435310.1
ENST00000485839.2
ENST00000367330.1
TMEM9
transmembrane protein 9
chr5_+_140593509 0.13 ENST00000341948.4
PCDHB13
protocadherin beta 13
chr12_+_60058458 0.13 ENST00000548610.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr7_+_134464376 0.13 ENST00000454108.1
ENST00000361675.2
CALD1
caldesmon 1
chr7_+_23146271 0.13 ENST00000545771.1
KLHL7
kelch-like family member 7
chr12_-_109915098 0.13 ENST00000542858.1
ENST00000542262.1
ENST00000424763.2
KCTD10
potassium channel tetramerization domain containing 10
chr4_+_78078304 0.13 ENST00000316355.5
ENST00000354403.5
ENST00000502280.1
CCNG2
cyclin G2
chr16_+_3704822 0.13 ENST00000414110.2
DNASE1
deoxyribonuclease I
chr1_-_201123586 0.13 ENST00000414605.2
ENST00000367334.5
ENST00000367332.1
TMEM9
transmembrane protein 9
chr4_+_54243798 0.13 ENST00000337488.6
ENST00000358575.5
ENST00000507922.1
FIP1L1
factor interacting with PAPOLA and CPSF1
chr4_+_26585686 0.13 ENST00000505206.1
ENST00000511789.1
TBC1D19
TBC1 domain family, member 19
chr1_+_147374915 0.12 ENST00000240986.4
GJA8
gap junction protein, alpha 8, 50kDa
chr10_+_115511213 0.12 ENST00000361048.1
PLEKHS1
pleckstrin homology domain containing, family S member 1
chr2_+_54683419 0.12 ENST00000356805.4
SPTBN1
spectrin, beta, non-erythrocytic 1
chr17_+_67498538 0.12 ENST00000589647.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr11_-_67981295 0.12 ENST00000405515.1
SUV420H1
suppressor of variegation 4-20 homolog 1 (Drosophila)
chr4_-_138453559 0.12 ENST00000511115.1
PCDH18
protocadherin 18
chr11_+_46402583 0.11 ENST00000359803.3
MDK
midkine (neurite growth-promoting factor 2)
chr14_-_91884150 0.11 ENST00000553403.1
CCDC88C
coiled-coil domain containing 88C
chrX_-_63425561 0.11 ENST00000374869.3
ENST00000330258.3
AMER1
APC membrane recruitment protein 1
chr3_+_183353356 0.11 ENST00000242810.6
ENST00000493074.1
ENST00000437402.1
ENST00000454495.2
ENST00000473045.1
ENST00000468101.1
ENST00000427201.2
ENST00000482138.1
ENST00000454652.2
KLHL24
kelch-like family member 24
chr15_+_89631647 0.11 ENST00000569550.1
ENST00000565066.1
ENST00000565973.1
ABHD2
abhydrolase domain containing 2
chr13_-_41593425 0.11 ENST00000239882.3
ELF1
E74-like factor 1 (ets domain transcription factor)
chr3_+_151986709 0.11 ENST00000495875.2
ENST00000493459.1
ENST00000324210.5
ENST00000459747.1
MBNL1
muscleblind-like splicing regulator 1
chr20_+_48884002 0.11 ENST00000425497.1
ENST00000445003.1
RP11-290F20.3
RP11-290F20.3
chr1_-_93645818 0.11 ENST00000370280.1
ENST00000479918.1
TMED5
transmembrane emp24 protein transport domain containing 5
chr1_-_32801825 0.11 ENST00000329421.7
MARCKSL1
MARCKS-like 1
chr7_+_102553430 0.11 ENST00000339431.4
ENST00000249377.4
LRRC17
leucine rich repeat containing 17
chr2_+_153191706 0.10 ENST00000288670.9
FMNL2
formin-like 2
chr15_+_85923856 0.10 ENST00000560302.1
ENST00000394518.2
ENST00000361243.2
ENST00000560256.1
AKAP13
A kinase (PRKA) anchor protein 13
chr15_-_73076030 0.10 ENST00000311669.8
ADPGK
ADP-dependent glucokinase
chr2_-_70475586 0.10 ENST00000416149.2
TIA1
TIA1 cytotoxic granule-associated RNA binding protein
chr2_-_166060571 0.10 ENST00000360093.3
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr5_-_114515734 0.10 ENST00000514154.1
ENST00000282369.3
TRIM36
tripartite motif containing 36
chr11_+_5509915 0.09 ENST00000322641.5
OR52D1
olfactory receptor, family 52, subfamily D, member 1
chr1_+_25071848 0.09 ENST00000374379.4
CLIC4
chloride intracellular channel 4
chr11_+_46402744 0.09 ENST00000533952.1
MDK
midkine (neurite growth-promoting factor 2)
chr2_-_166060552 0.09 ENST00000283254.7
ENST00000453007.1
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr7_-_150924121 0.09 ENST00000441774.1
ENST00000222388.2
ENST00000287844.2
ABCF2
ATP-binding cassette, sub-family F (GCN20), member 2
chr9_-_140196703 0.09 ENST00000356628.2
NRARP
NOTCH-regulated ankyrin repeat protein
chr1_-_26232951 0.09 ENST00000426559.2
ENST00000455785.2
STMN1
stathmin 1
chr16_+_56970567 0.09 ENST00000563911.1
HERPUD1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr5_+_140792614 0.09 ENST00000398610.2
PCDHGA10
protocadherin gamma subfamily A, 10
chr11_-_76155700 0.09 ENST00000572035.1
RP11-111M22.3
RP11-111M22.3
chr19_-_51472823 0.09 ENST00000310157.2
KLK6
kallikrein-related peptidase 6
chr9_+_108463234 0.08 ENST00000374688.1
TMEM38B
transmembrane protein 38B
chr13_+_24144509 0.08 ENST00000248484.4
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr12_+_104359641 0.08 ENST00000537100.1
TDG
thymine-DNA glycosylase
chr11_-_44971702 0.08 ENST00000533940.1
ENST00000533937.1
TP53I11
tumor protein p53 inducible protein 11
chr3_-_18466026 0.08 ENST00000417717.2
SATB1
SATB homeobox 1
chr3_+_14860469 0.08 ENST00000285046.5
FGD5
FYVE, RhoGEF and PH domain containing 5
chr8_+_126442563 0.08 ENST00000311922.3
TRIB1
tribbles pseudokinase 1
chr3_+_112930306 0.08 ENST00000495514.1
BOC
BOC cell adhesion associated, oncogene regulated
chr7_+_107224364 0.08 ENST00000491150.1
BCAP29
B-cell receptor-associated protein 29
chr13_+_111767650 0.08 ENST00000449979.1
ENST00000370623.3
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr9_+_75263565 0.08 ENST00000396237.3
TMC1
transmembrane channel-like 1
chr5_-_39425222 0.08 ENST00000320816.6
DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr3_+_135741576 0.08 ENST00000334546.2
PPP2R3A
protein phosphatase 2, regulatory subunit B'', alpha
chr4_-_103266355 0.08 ENST00000424970.2
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr11_+_60691924 0.08 ENST00000544065.1
ENST00000453848.2
ENST00000005286.4
TMEM132A
transmembrane protein 132A
chr2_-_217560248 0.08 ENST00000233813.4
IGFBP5
insulin-like growth factor binding protein 5
chr17_-_72358001 0.08 ENST00000375366.3
BTBD17
BTB (POZ) domain containing 17
chr19_-_44124019 0.08 ENST00000300811.3
ZNF428
zinc finger protein 428
chr4_-_186732048 0.07 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
SORBS2
sorbin and SH3 domain containing 2
chrX_+_129473859 0.07 ENST00000424447.1
SLC25A14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr18_-_32924372 0.07 ENST00000261332.6
ENST00000399061.3
ZNF24
zinc finger protein 24
chr6_-_127840453 0.07 ENST00000556132.1
SOGA3
SOGA family member 3
chr11_+_65339820 0.07 ENST00000316409.2
ENST00000449319.2
ENST00000530349.1
FAM89B
family with sequence similarity 89, member B
chr17_-_39041479 0.07 ENST00000167588.3
KRT20
keratin 20
chr1_-_156828810 0.07 ENST00000368195.3
INSRR
insulin receptor-related receptor
chr4_+_70861647 0.07 ENST00000246895.4
ENST00000381060.2
STATH
statherin
chr11_+_125365110 0.07 ENST00000527818.1
AP000708.1
AP000708.1
chr3_+_133118839 0.07 ENST00000302334.2
BFSP2
beaded filament structural protein 2, phakinin
chr9_-_88896977 0.07 ENST00000311534.6
ISCA1
iron-sulfur cluster assembly 1
chr1_+_240255166 0.07 ENST00000319653.9
FMN2
formin 2
chr13_+_76445187 0.07 ENST00000318245.4
C13orf45
chromosome 13 open reading frame 45
chr4_-_68620053 0.07 ENST00000420975.2
ENST00000226413.4
GNRHR
gonadotropin-releasing hormone receptor
chr19_+_10713112 0.07 ENST00000590382.1
ENST00000407327.4
SLC44A2
solute carrier family 44 (choline transporter), member 2
chr12_+_104359614 0.07 ENST00000266775.9
ENST00000544861.1
TDG
thymine-DNA glycosylase
chr3_-_57583130 0.07 ENST00000303436.6
ARF4
ADP-ribosylation factor 4
chr1_-_21503337 0.07 ENST00000400422.1
ENST00000602326.1
ENST00000411888.1
ENST00000438975.1
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr22_+_29168652 0.07 ENST00000249064.4
ENST00000444523.1
ENST00000448492.2
ENST00000421503.2
CCDC117
coiled-coil domain containing 117
chrX_+_135579670 0.06 ENST00000218364.4
HTATSF1
HIV-1 Tat specific factor 1
chr16_-_29478016 0.06 ENST00000549858.1
ENST00000551411.1
RP11-345J4.3
Uncharacterized protein
chr4_+_113152978 0.06 ENST00000309703.6
AP1AR
adaptor-related protein complex 1 associated regulatory protein
chr12_+_64238539 0.06 ENST00000357825.3
SRGAP1
SLIT-ROBO Rho GTPase activating protein 1
chr5_-_134871639 0.06 ENST00000314744.4
NEUROG1
neurogenin 1
chr11_+_46402482 0.06 ENST00000441869.1
MDK
midkine (neurite growth-promoting factor 2)
chr15_+_77224045 0.06 ENST00000320963.5
ENST00000394883.3
RCN2
reticulocalbin 2, EF-hand calcium binding domain
chr6_-_167040731 0.06 ENST00000265678.4
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr14_-_91884115 0.06 ENST00000389857.6
CCDC88C
coiled-coil domain containing 88C

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.2 0.6 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1 0.4 GO:0060139 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.1 0.3 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1 0.4 GO:0070662 mast cell proliferation(GO:0070662)
0.1 0.5 GO:0035549 positive regulation of interferon-beta secretion(GO:0035549)
0.1 0.4 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.1 0.3 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.1 0.3 GO:1904717 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.1 0.2 GO:0051086 chaperone mediated protein folding independent of cofactor(GO:0051086)
0.1 0.2 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.1 0.3 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.1 0.3 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 0.2 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.3 GO:0030421 defecation(GO:0030421)
0.0 0.8 GO:0051601 exocyst localization(GO:0051601)
0.0 0.2 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.8 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.2 GO:0035026 leading edge cell differentiation(GO:0035026)
0.0 0.1 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.0 0.6 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.2 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 1.0 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.2 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.2 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.2 GO:0070858 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.0 0.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.3 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.1 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.0 0.7 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.1 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.0 0.4 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0 0.2 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.1 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.5 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.6 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.2 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:2000866 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.0 0.1 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.0 0.1 GO:0071469 cellular response to alkaline pH(GO:0071469)
0.0 0.1 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.0 0.1 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.1 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.0 0.2 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.1 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.0 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.1 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.1 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.1 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.0 GO:0034241 macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241)
0.0 0.1 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.1 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
0.0 0.2 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.0 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.0 0.1 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.0 GO:0009597 detection of virus(GO:0009597)
0.0 0.1 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.4 GO:0035728 response to hepatocyte growth factor(GO:0035728)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 0.3 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.1 GO:1990015 mesaxon(GO:0097453) ensheathing process(GO:1990015)
0.0 1.0 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0 0.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.8 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.4 GO:0005922 connexon complex(GO:0005922)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.1 GO:0032437 cuticular plate(GO:0032437)
0.0 0.3 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0043219 lateral loop(GO:0043219)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.2 GO:0032059 bleb(GO:0032059)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.0 GO:0034680 integrin alpha1-beta1 complex(GO:0034665) integrin alpha3-beta1 complex(GO:0034667) integrin alpha10-beta1 complex(GO:0034680) integrin alpha11-beta1 complex(GO:0034681)
0.0 0.2 GO:0097386 glial cell projection(GO:0097386)
0.0 0.2 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.2 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.2 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 0.1 GO:0000322 storage vacuole(GO:0000322)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0033677 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) DNA/RNA helicase activity(GO:0033677)
0.1 0.3 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.1 0.6 GO:0019211 phosphatase activator activity(GO:0019211)
0.1 1.1 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.2 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.2 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.2 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.3 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.0 0.7 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.1 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.1 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.6 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0046848 hydroxyapatite binding(GO:0046848)
0.0 0.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.3 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.2 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.2 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.3 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0000182 rDNA binding(GO:0000182)
0.0 1.0 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.1 GO:0005243 gap junction channel activity(GO:0005243)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.1 PID TNF PATHWAY TNF receptor signaling pathway
0.0 1.1 PID FGF PATHWAY FGF signaling pathway
0.0 0.7 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.7 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.4 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.4 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.2 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.2 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.2 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs