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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for SOX8

Z-value: 0.75

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Transcription factors associated with SOX8

Gene Symbol Gene ID Gene Info
SOX8
ENSG00000005513.9 SRY-box transcription factor 8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX8hg19_v2_chr16_+_1031762_10318080.116.1e-01Click!

Activity profile of SOX8 motif

Sorted Z-values of SOX8 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr21_-_47352477 1.45 ENST00000593412.1
PRED62
Uncharacterized protein
chr2_-_175711133 1.23 ENST00000409597.1
ENST00000413882.1
CHN1
chimerin 1
chr15_+_45926919 0.89 ENST00000561735.1
ENST00000260324.7
SQRDL
sulfide quinone reductase-like (yeast)
chr4_-_47983519 0.86 ENST00000358519.4
ENST00000544810.1
ENST00000402813.3
CNGA1
cyclic nucleotide gated channel alpha 1
chr10_+_88414338 0.84 ENST00000241891.5
ENST00000443292.1
OPN4
opsin 4
chr10_+_88414298 0.83 ENST00000372071.2
OPN4
opsin 4
chr10_+_103986085 0.79 ENST00000370005.3
ELOVL3
ELOVL fatty acid elongase 3
chr1_+_13516066 0.73 ENST00000332192.6
PRAMEF21
PRAME family member 21
chr20_-_44176013 0.69 ENST00000555685.1
EPPIN
epididymal peptidase inhibitor
chr7_+_100303676 0.67 ENST00000303151.4
POP7
processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae)
chr20_-_5426332 0.66 ENST00000420529.1
LINC00658
long intergenic non-protein coding RNA 658
chr2_+_233527443 0.59 ENST00000410095.1
EFHD1
EF-hand domain family, member D1
chr15_-_58306295 0.56 ENST00000559517.1
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr12_-_39837192 0.56 ENST00000361961.3
ENST00000395670.3
KIF21A
kinesin family member 21A
chr3_-_52090461 0.53 ENST00000296483.6
ENST00000495880.1
DUSP7
dual specificity phosphatase 7
chr5_-_146781153 0.53 ENST00000520473.1
DPYSL3
dihydropyrimidinase-like 3
chr4_+_86525299 0.52 ENST00000512201.1
ARHGAP24
Rho GTPase activating protein 24
chr4_+_74347400 0.52 ENST00000226355.3
AFM
afamin
chr12_-_10151773 0.51 ENST00000298527.6
ENST00000348658.4
CLEC1B
C-type lectin domain family 1, member B
chr18_-_33702078 0.50 ENST00000586829.1
SLC39A6
solute carrier family 39 (zinc transporter), member 6
chrX_+_18725758 0.48 ENST00000472826.1
ENST00000544635.1
ENST00000496075.2
PPEF1
protein phosphatase, EF-hand calcium binding domain 1
chr4_+_89299994 0.48 ENST00000264346.7
HERC6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr17_-_34207295 0.45 ENST00000463941.1
ENST00000293272.3
CCL5
chemokine (C-C motif) ligand 5
chr14_+_75745477 0.44 ENST00000303562.4
ENST00000554617.1
ENST00000554212.1
ENST00000535987.1
ENST00000555242.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr3_-_123339418 0.43 ENST00000583087.1
MYLK
myosin light chain kinase
chr15_+_34261089 0.42 ENST00000383263.5
CHRM5
cholinergic receptor, muscarinic 5
chr2_+_89986318 0.41 ENST00000491977.1
IGKV2D-29
immunoglobulin kappa variable 2D-29
chr17_+_41132564 0.39 ENST00000361677.1
ENST00000589705.1
RUNDC1
RUN domain containing 1
chr19_-_37663332 0.39 ENST00000392157.2
ZNF585A
zinc finger protein 585A
chr16_+_57392684 0.38 ENST00000219235.4
CCL22
chemokine (C-C motif) ligand 22
chr3_-_54962100 0.38 ENST00000273286.5
LRTM1
leucine-rich repeats and transmembrane domains 1
chr1_+_26496362 0.38 ENST00000374266.5
ENST00000270812.5
ZNF593
zinc finger protein 593
chr12_+_45686457 0.37 ENST00000441606.2
ANO6
anoctamin 6
chr12_-_123201337 0.37 ENST00000528880.2
HCAR3
hydroxycarboxylic acid receptor 3
chr1_+_13742808 0.36 ENST00000602960.1
PRAMEF20
PRAME family member 20
chr18_+_61575200 0.36 ENST00000238508.3
SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr1_+_110577229 0.36 ENST00000369795.3
ENST00000369794.2
STRIP1
striatin interacting protein 1
chr14_-_21562648 0.36 ENST00000555270.1
ZNF219
zinc finger protein 219
chr4_+_156680153 0.35 ENST00000502959.1
ENST00000505764.1
ENST00000507146.1
ENST00000264424.8
ENST00000503520.1
GUCY1B3
guanylate cyclase 1, soluble, beta 3
chr1_-_200992827 0.34 ENST00000332129.2
ENST00000422435.2
KIF21B
kinesin family member 21B
chr3_-_47934234 0.34 ENST00000420772.2
MAP4
microtubule-associated protein 4
chr2_+_74425689 0.33 ENST00000394053.2
ENST00000409804.1
ENST00000264090.4
ENST00000394050.3
ENST00000409601.1
MTHFD2
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
chr7_-_122339162 0.32 ENST00000340112.2
RNF133
ring finger protein 133
chr5_-_160279207 0.32 ENST00000327245.5
ATP10B
ATPase, class V, type 10B
chr18_+_32173276 0.32 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
DTNA
dystrobrevin, alpha
chr2_-_120124258 0.32 ENST00000409877.1
ENST00000409523.1
ENST00000409466.2
ENST00000414534.1
C2orf76
chromosome 2 open reading frame 76
chr1_-_222763240 0.31 ENST00000352967.4
ENST00000391882.1
ENST00000543857.1
TAF1A
TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
chr3_+_173302222 0.31 ENST00000361589.4
NLGN1
neuroligin 1
chr5_-_94417339 0.31 ENST00000429576.2
ENST00000508509.1
ENST00000510732.1
MCTP1
multiple C2 domains, transmembrane 1
chr4_+_156680143 0.31 ENST00000505154.1
GUCY1B3
guanylate cyclase 1, soluble, beta 3
chr19_+_45681997 0.31 ENST00000433642.2
BLOC1S3
biogenesis of lysosomal organelles complex-1, subunit 3
chr11_+_10477733 0.31 ENST00000528723.1
AMPD3
adenosine monophosphate deaminase 3
chr15_-_89755034 0.31 ENST00000563254.1
RLBP1
retinaldehyde binding protein 1
chr1_-_231005310 0.31 ENST00000470540.1
C1orf198
chromosome 1 open reading frame 198
chr12_+_113354341 0.31 ENST00000553152.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr12_-_50101165 0.31 ENST00000352151.5
ENST00000335154.5
ENST00000293590.5
FMNL3
formin-like 3
chr2_-_163008903 0.30 ENST00000418842.2
ENST00000375497.3
GCG
glucagon
chr4_-_69536346 0.30 ENST00000338206.5
UGT2B15
UDP glucuronosyltransferase 2 family, polypeptide B15
chr6_-_136788001 0.29 ENST00000544465.1
MAP7
microtubule-associated protein 7
chr7_-_27169801 0.28 ENST00000511914.1
HOXA4
homeobox A4
chr6_-_52668605 0.28 ENST00000334575.5
GSTA1
glutathione S-transferase alpha 1
chr12_+_122242597 0.28 ENST00000267197.5
SETD1B
SET domain containing 1B
chr19_-_37663572 0.27 ENST00000588354.1
ENST00000292841.5
ENST00000355533.2
ENST00000356958.4
ZNF585A
zinc finger protein 585A
chr11_+_67219867 0.27 ENST00000438189.2
CABP4
calcium binding protein 4
chr2_-_3606206 0.27 ENST00000315212.3
RNASEH1
ribonuclease H1
chr3_-_21792838 0.27 ENST00000281523.2
ZNF385D
zinc finger protein 385D
chr11_+_5474638 0.26 ENST00000341449.2
OR51I2
olfactory receptor, family 51, subfamily I, member 2
chr9_-_128246769 0.26 ENST00000444226.1
MAPKAP1
mitogen-activated protein kinase associated protein 1
chr15_-_50557863 0.26 ENST00000543581.1
HDC
histidine decarboxylase
chr4_+_155484155 0.26 ENST00000509493.1
FGB
fibrinogen beta chain
chr20_+_48807351 0.26 ENST00000303004.3
CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr2_+_26624775 0.25 ENST00000288710.2
DRC1
dynein regulatory complex subunit 1 homolog (Chlamydomonas)
chr11_+_57435219 0.25 ENST00000527985.1
ENST00000287169.3
ZDHHC5
zinc finger, DHHC-type containing 5
chr2_+_97203082 0.25 ENST00000454558.2
ARID5A
AT rich interactive domain 5A (MRF1-like)
chr4_-_140544386 0.24 ENST00000561977.1
RP11-308D13.3
RP11-308D13.3
chr11_+_12308447 0.24 ENST00000256186.2
MICALCL
MICAL C-terminal like
chr3_+_137906109 0.24 ENST00000481646.1
ENST00000469044.1
ENST00000491704.1
ENST00000461600.1
ARMC8
armadillo repeat containing 8
chr19_+_51728316 0.24 ENST00000436584.2
ENST00000421133.2
ENST00000391796.3
ENST00000262262.4
CD33
CD33 molecule
chr18_+_32455201 0.24 ENST00000590831.2
DTNA
dystrobrevin, alpha
chr5_-_94417314 0.24 ENST00000505208.1
MCTP1
multiple C2 domains, transmembrane 1
chr20_+_32399093 0.24 ENST00000217402.2
CHMP4B
charged multivesicular body protein 4B
chr14_+_95078714 0.23 ENST00000393078.3
ENST00000393080.4
ENST00000467132.1
SERPINA3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr3_+_173116225 0.23 ENST00000457714.1
NLGN1
neuroligin 1
chr2_-_223520770 0.23 ENST00000536361.1
FARSB
phenylalanyl-tRNA synthetase, beta subunit
chrX_-_54824673 0.23 ENST00000218436.6
ITIH6
inter-alpha-trypsin inhibitor heavy chain family, member 6
chr12_-_50101003 0.22 ENST00000550488.1
FMNL3
formin-like 3
chr15_-_62937380 0.22 ENST00000560347.1
ENST00000558940.1
RP11-625H11.1
Uncharacterized protein
chr3_+_97887544 0.22 ENST00000356526.2
OR5H15
olfactory receptor, family 5, subfamily H, member 15
chr5_+_32788945 0.22 ENST00000326958.1
AC026703.1
AC026703.1
chr2_+_166326157 0.22 ENST00000421875.1
ENST00000314499.7
ENST00000409664.1
CSRNP3
cysteine-serine-rich nuclear protein 3
chr9_-_113761720 0.22 ENST00000541779.1
ENST00000374430.2
LPAR1
lysophosphatidic acid receptor 1
chr11_-_121986923 0.22 ENST00000560104.1
BLID
BH3-like motif containing, cell death inducer
chr11_-_128457446 0.22 ENST00000392668.4
ETS1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
chr22_-_30722912 0.22 ENST00000215790.7
TBC1D10A
TBC1 domain family, member 10A
chr11_-_46142615 0.21 ENST00000529734.1
ENST00000323180.6
PHF21A
PHD finger protein 21A
chr9_-_116837249 0.21 ENST00000466610.2
AMBP
alpha-1-microglobulin/bikunin precursor
chr9_+_127624387 0.21 ENST00000353214.2
ARPC5L
actin related protein 2/3 complex, subunit 5-like
chr12_+_20848282 0.21 ENST00000545604.1
SLCO1C1
solute carrier organic anion transporter family, member 1C1
chr22_-_30722866 0.21 ENST00000403477.3
TBC1D10A
TBC1 domain family, member 10A
chr4_-_70518941 0.21 ENST00000286604.4
ENST00000505512.1
ENST00000514019.1
UGT2A1
UGT2A1
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
chr16_+_21244986 0.21 ENST00000311620.5
ANKS4B
ankyrin repeat and sterile alpha motif domain containing 4B
chr14_+_39583427 0.21 ENST00000308317.6
ENST00000396249.2
ENST00000250379.8
ENST00000534684.2
ENST00000527381.1
GEMIN2
gem (nuclear organelle) associated protein 2
chr10_-_38265517 0.20 ENST00000302609.7
ZNF25
zinc finger protein 25
chr15_+_78830023 0.20 ENST00000599596.1
AC027228.1
HCG2005369; Uncharacterized protein
chr12_+_20848377 0.20 ENST00000540354.1
ENST00000266509.2
ENST00000381552.1
SLCO1C1
solute carrier organic anion transporter family, member 1C1
chr11_-_41481135 0.20 ENST00000528697.1
ENST00000530763.1
LRRC4C
leucine rich repeat containing 4C
chr17_+_2240916 0.20 ENST00000574563.1
SGSM2
small G protein signaling modulator 2
chr16_+_87985029 0.20 ENST00000439677.1
ENST00000286122.7
ENST00000355163.5
ENST00000454563.1
ENST00000479780.2
ENST00000393208.2
ENST00000412691.1
ENST00000355022.4
BANP
BTG3 associated nuclear protein
chr14_+_88471468 0.20 ENST00000267549.3
GPR65
G protein-coupled receptor 65
chr7_+_23145366 0.20 ENST00000339077.5
ENST00000322275.5
ENST00000539124.1
ENST00000542558.1
KLHL7
kelch-like family member 7
chr3_+_14693247 0.20 ENST00000383794.3
ENST00000303688.7
CCDC174
coiled-coil domain containing 174
chr19_-_8213753 0.19 ENST00000601739.1
FBN3
fibrillin 3
chr3_-_55001115 0.19 ENST00000493075.1
LRTM1
leucine-rich repeats and transmembrane domains 1
chr16_-_18911366 0.19 ENST00000565224.1
SMG1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr7_+_64126535 0.18 ENST00000344930.3
ZNF107
zinc finger protein 107
chr11_+_9482551 0.18 ENST00000438144.2
ENST00000526657.1
ENST00000299606.2
ENST00000534265.1
ENST00000412390.2
ZNF143
zinc finger protein 143
chr17_-_19648683 0.18 ENST00000573368.1
ENST00000457500.2
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr4_-_100356551 0.18 ENST00000209665.4
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr3_+_577893 0.18 ENST00000420823.1
ENST00000442809.1
AC090044.1
AC090044.1
chr19_+_52076425 0.18 ENST00000436511.2
ZNF175
zinc finger protein 175
chr3_+_138340049 0.18 ENST00000464668.1
FAIM
Fas apoptotic inhibitory molecule
chr3_-_193272588 0.18 ENST00000295548.3
ATP13A4
ATPase type 13A4
chr12_-_123187890 0.18 ENST00000328880.5
HCAR2
hydroxycarboxylic acid receptor 2
chr12_+_14927270 0.18 ENST00000544848.1
H2AFJ
H2A histone family, member J
chr1_+_144811943 0.18 ENST00000281815.8
NBPF9
neuroblastoma breakpoint family, member 9
chr4_+_71248795 0.18 ENST00000304915.3
SMR3B
submaxillary gland androgen regulated protein 3B
chr3_+_185080908 0.17 ENST00000265026.3
MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr16_+_87636474 0.17 ENST00000284262.2
JPH3
junctophilin 3
chr15_-_38519066 0.17 ENST00000561320.1
ENST00000561161.1
RP11-346D14.1
RP11-346D14.1
chr2_+_102413726 0.17 ENST00000350878.4
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr4_+_155484103 0.17 ENST00000302068.4
FGB
fibrinogen beta chain
chr11_+_9482512 0.17 ENST00000396602.2
ENST00000530463.1
ENST00000533542.1
ENST00000532577.1
ENST00000396597.3
ZNF143
zinc finger protein 143
chr10_-_75676400 0.16 ENST00000412307.2
C10orf55
chromosome 10 open reading frame 55
chr11_+_43702322 0.16 ENST00000395700.4
HSD17B12
hydroxysteroid (17-beta) dehydrogenase 12
chr6_-_31689456 0.16 ENST00000495859.1
ENST00000375819.2
LY6G6C
lymphocyte antigen 6 complex, locus G6C
chr8_+_7693993 0.16 ENST00000314265.2
DEFB104A
defensin, beta 104A
chr2_-_151344172 0.16 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
RND3
Rho family GTPase 3
chr3_-_190167571 0.16 ENST00000354905.2
TMEM207
transmembrane protein 207
chr6_+_31021225 0.16 ENST00000565192.1
ENST00000562344.1
HCG22
HLA complex group 22
chr11_-_57177586 0.15 ENST00000529411.1
RP11-872D17.8
Uncharacterized protein
chr7_-_127255982 0.15 ENST00000338516.3
ENST00000378740.2
PAX4
paired box 4
chr11_-_62995986 0.15 ENST00000403374.2
SLC22A25
solute carrier family 22, member 25
chr6_-_138539627 0.15 ENST00000527246.2
PBOV1
prostate and breast cancer overexpressed 1
chr8_+_38758737 0.15 ENST00000521746.1
ENST00000420274.1
PLEKHA2
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
chr19_+_1524072 0.15 ENST00000454744.2
PLK5
polo-like kinase 5
chr17_-_8021710 0.15 ENST00000380149.1
ENST00000448843.2
ALOXE3
arachidonate lipoxygenase 3
chr10_-_4285923 0.15 ENST00000418372.1
ENST00000608792.1
LINC00702
long intergenic non-protein coding RNA 702
chr16_+_618837 0.15 ENST00000409439.2
PIGQ
phosphatidylinositol glycan anchor biosynthesis, class Q
chr14_-_106642049 0.15 ENST00000390605.2
IGHV1-18
immunoglobulin heavy variable 1-18
chr8_-_20040638 0.15 ENST00000519026.1
ENST00000276373.5
ENST00000440926.1
ENST00000437980.1
SLC18A1
solute carrier family 18 (vesicular monoamine transporter), member 1
chr16_+_53241854 0.14 ENST00000565803.1
CHD9
chromodomain helicase DNA binding protein 9
chr11_+_60995849 0.14 ENST00000537932.1
PGA4
pepsinogen 4, group I (pepsinogen A)
chr12_+_82347498 0.14 ENST00000550506.1
RP11-362A1.1
RP11-362A1.1
chr8_-_91095099 0.14 ENST00000265431.3
CALB1
calbindin 1, 28kDa
chr7_-_38289173 0.14 ENST00000436911.2
TRGC2
T cell receptor gamma constant 2
chr16_+_31271274 0.14 ENST00000287497.8
ENST00000544665.3
ITGAM
integrin, alpha M (complement component 3 receptor 3 subunit)
chr7_+_80275752 0.14 ENST00000419819.2
CD36
CD36 molecule (thrombospondin receptor)
chr22_-_50708781 0.14 ENST00000449719.2
ENST00000330651.6
MAPK11
mitogen-activated protein kinase 11
chr12_+_133066137 0.14 ENST00000434748.2
FBRSL1
fibrosin-like 1
chr9_-_130533615 0.14 ENST00000373277.4
SH2D3C
SH2 domain containing 3C
chr15_+_62853562 0.13 ENST00000561311.1
TLN2
talin 2
chr3_+_156008809 0.13 ENST00000302490.8
KCNAB1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr18_-_47376197 0.13 ENST00000592688.1
MYO5B
myosin VB
chr14_+_52327350 0.13 ENST00000555472.1
ENST00000556766.1
GNG2
guanine nucleotide binding protein (G protein), gamma 2
chr11_+_112130988 0.13 ENST00000595053.1
AP002884.2
LOC100132686 protein; Uncharacterized protein
chr16_+_30075783 0.13 ENST00000412304.2
ALDOA
aldolase A, fructose-bisphosphate
chr16_+_30075463 0.13 ENST00000562168.1
ENST00000569545.1
ALDOA
aldolase A, fructose-bisphosphate
chr7_+_23145347 0.13 ENST00000322231.7
KLHL7
kelch-like family member 7
chr16_+_30075595 0.12 ENST00000563060.2
ALDOA
aldolase A, fructose-bisphosphate
chr7_-_229557 0.12 ENST00000514988.1
AC145676.2
Uncharacterized protein
chr5_-_160973649 0.12 ENST00000393959.1
ENST00000517547.1
GABRB2
gamma-aminobutyric acid (GABA) A receptor, beta 2
chr11_+_125774362 0.12 ENST00000530414.1
ENST00000530129.2
DDX25
DEAD (Asp-Glu-Ala-Asp) box helicase 25
chr1_-_238649319 0.12 ENST00000400946.2
RP11-371I1.2
long intergenic non-protein coding RNA 1139
chr2_+_158114051 0.12 ENST00000259056.4
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr18_-_5396271 0.12 ENST00000579951.1
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr3_-_186288097 0.12 ENST00000446782.1
TBCCD1
TBCC domain containing 1
chr19_-_47287990 0.12 ENST00000593713.1
ENST00000598022.1
ENST00000434726.2
SLC1A5
solute carrier family 1 (neutral amino acid transporter), member 5
chr17_-_66597530 0.11 ENST00000592554.1
FAM20A
family with sequence similarity 20, member A
chr4_-_38858428 0.11 ENST00000436693.2
ENST00000508254.1
ENST00000514655.1
ENST00000506146.1
TLR6
TLR1
toll-like receptor 6
toll-like receptor 1
chr11_+_74862140 0.11 ENST00000525650.1
ENST00000454962.2
SLCO2B1
solute carrier organic anion transporter family, member 2B1
chr6_+_32605134 0.11 ENST00000343139.5
ENST00000395363.1
ENST00000496318.1
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr9_-_95244781 0.11 ENST00000375544.3
ENST00000375543.1
ENST00000395538.3
ENST00000450139.2
ASPN
asporin
chr20_+_32150140 0.11 ENST00000344201.3
ENST00000346541.3
ENST00000397800.1
ENST00000397798.2
ENST00000492345.1
CBFA2T2
core-binding factor, runt domain, alpha subunit 2; translocated to, 2
chr1_+_153330322 0.11 ENST00000368738.3
S100A9
S100 calcium binding protein A9
chr1_+_152956549 0.10 ENST00000307122.2
SPRR1A
small proline-rich protein 1A
chr17_-_41132410 0.10 ENST00000409446.3
ENST00000453594.1
ENST00000409399.1
ENST00000421990.2
PTGES3L
PTGES3L-AARSD1
prostaglandin E synthase 3 (cytosolic)-like
PTGES3L-AARSD1 readthrough
chr3_+_98216448 0.10 ENST00000427338.1
OR5K2
olfactory receptor, family 5, subfamily K, member 2
chr22_-_43411106 0.10 ENST00000453643.1
ENST00000263246.3
ENST00000337959.4
PACSIN2
protein kinase C and casein kinase substrate in neurons 2
chr4_-_10686373 0.10 ENST00000442825.2
CLNK
cytokine-dependent hematopoietic cell linker
chr18_-_3845321 0.10 ENST00000539435.1
ENST00000400147.2
DLGAP1
discs, large (Drosophila) homolog-associated protein 1
chr12_-_11548496 0.10 ENST00000389362.4
ENST00000565533.1
ENST00000546254.1
PRB2
PRB1
proline-rich protein BstNI subfamily 2
proline-rich protein BstNI subfamily 1
chr6_-_116833500 0.10 ENST00000356128.4
TRAPPC3L
trafficking protein particle complex 3-like
chr12_-_100660833 0.10 ENST00000551642.1
ENST00000416321.1
ENST00000550587.1
ENST00000549249.1
DEPDC4
DEP domain containing 4
chrX_+_15767971 0.10 ENST00000479740.1
ENST00000454127.2
CA5B
carbonic anhydrase VB, mitochondrial
chr9_+_84603687 0.09 ENST00000344803.2
SPATA31D1
SPATA31 subfamily D, member 1
chr3_+_35683651 0.09 ENST00000187397.4
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr1_-_247921982 0.09 ENST00000408896.2
OR1C1
olfactory receptor, family 1, subfamily C, member 1
chr1_-_38512450 0.09 ENST00000373012.2
POU3F1
POU class 3 homeobox 1
chr22_-_50523760 0.09 ENST00000395876.2
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr5_-_78809950 0.09 ENST00000334082.6
HOMER1
homer homolog 1 (Drosophila)

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0099545 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.1 0.5 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 0.7 GO:1901318 negative regulation of sperm motility(GO:1901318)
0.1 1.9 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 0.4 GO:0097045 phosphatidylserine exposure on blood platelet(GO:0097045)
0.1 0.3 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 0.8 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.3 GO:0001694 histamine biosynthetic process(GO:0001694)
0.1 0.7 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.1 0.3 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.1 0.2 GO:1904106 protein localization to microvillus(GO:1904106)
0.1 0.6 GO:0035799 ureter maturation(GO:0035799)
0.1 0.4 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.1 0.2 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.1 0.3 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.4 GO:0001661 conditioned taste aversion(GO:0001661)
0.1 0.2 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.1 0.3 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.4 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.2 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.0 0.4 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 0.3 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.4 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.4 GO:0071726 toll-like receptor TLR6:TLR2 signaling pathway(GO:0038124) response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
0.0 0.1 GO:0044691 tooth eruption(GO:0044691)
0.0 0.3 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 1.3 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.1 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.6 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.3 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.2 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.4 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:0071314 cellular response to cocaine(GO:0071314)
0.0 0.1 GO:1903803 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.0 1.2 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.5 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.2 GO:0030578 PML body organization(GO:0030578)
0.0 0.1 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 0.4 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.0 0.1 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.0 0.6 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.1 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.0 0.5 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.4 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.3 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.1 GO:0051661 maintenance of centrosome location(GO:0051661) maintenance of Golgi location(GO:0051684)
0.0 0.1 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.0 0.5 GO:0030220 platelet formation(GO:0030220)
0.0 0.1 GO:0060539 diaphragm development(GO:0060539)
0.0 0.1 GO:0032439 endosome localization(GO:0032439)
0.0 0.1 GO:1901382 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.0 0.1 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.1 GO:0070560 protein secretion by platelet(GO:0070560)
0.0 0.1 GO:0070836 caveola assembly(GO:0070836)
0.0 0.0 GO:0033386 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.0 0.2 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.1 GO:0032690 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.0 0.3 GO:0046655 folic acid metabolic process(GO:0046655)
0.0 0.0 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.6 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.5 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.3 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.1 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.1 GO:0046874 quinolinate metabolic process(GO:0046874)
0.0 0.5 GO:0051180 vitamin transport(GO:0051180)
0.0 0.2 GO:0015747 urate transport(GO:0015747)
0.0 0.3 GO:0060285 cilium-dependent cell motility(GO:0060285)
0.0 0.1 GO:0042090 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.8 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.1 GO:0010668 ectodermal cell differentiation(GO:0010668)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 0.9 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 0.7 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 0.4 GO:0035976 AP1 complex(GO:0035976)
0.1 1.7 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.2 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.3 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.1 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.0 0.4 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.2 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.1 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 0.1 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.1 GO:0097486 multivesicular body lumen(GO:0097486)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.1 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.9 GO:0005871 kinesin complex(GO:0005871)
0.0 0.1 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.1 GO:0045179 apical cortex(GO:0045179)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 0.5 GO:0008431 vitamin E binding(GO:0008431)
0.1 0.4 GO:0000035 acyl binding(GO:0000035) phosphopantetheine binding(GO:0031177)
0.1 0.3 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.1 0.8 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.9 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 0.5 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.1 0.4 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 0.7 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 0.3 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 0.2 GO:0019862 IgA binding(GO:0019862)
0.0 0.1 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.0 0.4 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.2 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.0 0.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.3 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.5 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.3 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.0 0.6 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.4 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.4 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.3 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.1 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.0 1.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.7 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.5 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.1 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 0.1 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.1 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0 0.3 GO:0005549 odorant binding(GO:0005549)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.0 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.4 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.1 GO:0001851 complement component C3b binding(GO:0001851)
0.0 0.5 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.2 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.4 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.2 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 REACTOME OPSINS Genes involved in Opsins
0.0 0.6 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.9 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.5 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.5 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.4 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.7 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.5 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.3 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter