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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for SOX9

Z-value: 0.88

Motif logo

Transcription factors associated with SOX9

Gene Symbol Gene ID Gene Info
ENSG00000125398.5 SRY-box transcription factor 9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX9hg19_v2_chr17_+_70117153_701171740.183.9e-01Click!

Activity profile of SOX9 motif

Sorted Z-values of SOX9 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_102106829 2.25 ENST00000370355.2
stearoyl-CoA desaturase (delta-9-desaturase)
chr7_+_77167343 2.14 ENST00000433369.2
ENST00000415482.2
protein tyrosine phosphatase, non-receptor type 12
chr4_+_41614720 1.99 ENST00000509277.1
LIM and calponin homology domains 1
chr7_-_11871815 1.96 ENST00000423059.4
thrombospondin, type I, domain containing 7A
chr17_-_42276574 1.90 ENST00000589805.1
ataxin 7-like 3
chr4_+_41614909 1.89 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIM and calponin homology domains 1
chr14_-_51027838 1.86 ENST00000555216.1
mitogen-activated protein kinase kinase kinase kinase 5
chr3_-_149051194 1.85 ENST00000470080.1
transmembrane 4 L six family member 18
chr7_+_155090271 1.66 ENST00000476756.1
insulin induced gene 1
chr17_-_14683517 1.60 ENST00000379640.1
AC005863.1
chr1_-_85930246 1.53 ENST00000426972.3
dimethylarginine dimethylaminohydrolase 1
chr3_-_149051444 1.36 ENST00000296059.2
transmembrane 4 L six family member 18
chr6_-_75915757 1.33 ENST00000322507.8
collagen, type XII, alpha 1
chr5_-_43313574 1.32 ENST00000325110.6
ENST00000433297.2
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chrX_-_117107542 1.21 ENST00000371878.1
kelch-like family member 13
chr12_-_6233828 1.16 ENST00000572068.1
ENST00000261405.5
von Willebrand factor
chr14_+_53019993 1.13 ENST00000542169.2
ENST00000555622.1
G protein-coupled receptor 137C
chr19_+_10765699 1.13 ENST00000590009.1
interleukin enhancer binding factor 3, 90kDa
chr1_+_164528866 1.12 ENST00000420696.2
pre-B-cell leukemia homeobox 1
chr11_-_10830463 1.08 ENST00000527419.1
ENST00000530211.1
ENST00000530702.1
ENST00000524932.1
ENST00000532570.1
eukaryotic translation initiation factor 4 gamma, 2
chr4_-_186732048 1.03 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
sorbin and SH3 domain containing 2
chr5_+_74633036 1.00 ENST00000343975.5
3-hydroxy-3-methylglutaryl-CoA reductase
chrX_+_84499081 0.95 ENST00000276123.3
zinc finger protein 711
chr12_-_25055177 0.95 ENST00000538118.1
branched chain amino-acid transaminase 1, cytosolic
chr12_-_88974236 0.94 ENST00000228280.5
ENST00000552044.1
ENST00000357116.4
KIT ligand
chrX_-_45060135 0.93 ENST00000398000.2
ENST00000377934.4
chromosome X open reading frame 36
chr8_-_80993010 0.93 ENST00000537855.1
ENST00000520527.1
ENST00000517427.1
ENST00000448733.2
ENST00000379097.3
tumor protein D52
chr20_-_39317868 0.93 ENST00000373313.2
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
chr8_+_70378852 0.91 ENST00000525061.1
ENST00000458141.2
ENST00000260128.4
sulfatase 1
chr1_+_185703513 0.90 ENST00000271588.4
ENST00000367492.2
hemicentin 1
chr5_+_74632993 0.89 ENST00000287936.4
3-hydroxy-3-methylglutaryl-CoA reductase
chr14_-_38725573 0.85 ENST00000342213.2
C-type lectin domain family 14, member A
chr14_+_63671105 0.85 ENST00000316754.3
ras homolog family member J
chr1_+_29241027 0.80 ENST00000373797.1
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr14_-_65569057 0.80 ENST00000555419.1
ENST00000341653.2
MYC associated factor X
chr6_+_37787704 0.79 ENST00000474522.1
zinc finger, AN1-type domain 3
chr11_+_63953691 0.79 ENST00000543847.1
stress-induced-phosphoprotein 1
chr9_-_139658965 0.79 ENST00000316144.5
lipocalin 15
chr11_+_128563948 0.75 ENST00000534087.2
Fli-1 proto-oncogene, ETS transcription factor
chr2_-_70475701 0.71 ENST00000282574.4
TIA1 cytotoxic granule-associated RNA binding protein
chr21_+_26934165 0.71 ENST00000456917.1
MIR155 host gene (non-protein coding)
chr1_-_182360498 0.71 ENST00000417584.2
glutamate-ammonia ligase
chr17_+_26646175 0.71 ENST00000583381.1
ENST00000582113.1
ENST00000582384.1
transmembrane protein 97
chr8_-_38326119 0.70 ENST00000356207.5
ENST00000326324.6
fibroblast growth factor receptor 1
chr3_-_112329110 0.70 ENST00000479368.1
coiled-coil domain containing 80
chrX_+_41193407 0.70 ENST00000457138.2
ENST00000441189.2
DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
chr7_+_16793160 0.69 ENST00000262067.4
tetraspanin 13
chrX_+_48380205 0.68 ENST00000446158.1
ENST00000414061.1
emopamil binding protein (sterol isomerase)
chr1_-_173991434 0.68 ENST00000367696.2
ring finger and CCCH-type domains 1
chr14_-_88459182 0.68 ENST00000544807.2
galactosylceramidase
chr4_+_78079450 0.67 ENST00000395640.1
ENST00000512918.1
cyclin G2
chr4_-_110723194 0.66 ENST00000394635.3
complement factor I
chr14_+_32546145 0.65 ENST00000556611.1
ENST00000539826.2
Rho GTPase activating protein 5
chr19_+_16187816 0.65 ENST00000588410.1
tropomyosin 4
chr9_-_123476612 0.65 ENST00000426959.1
multiple EGF-like-domains 9
chr15_-_59041768 0.65 ENST00000402627.1
ENST00000396140.2
ENST00000559053.1
ENST00000561288.1
ADAM metallopeptidase domain 10
chr1_-_68698197 0.64 ENST00000370973.2
ENST00000370971.1
wntless Wnt ligand secretion mediator
chr8_-_82395461 0.63 ENST00000256104.4
fatty acid binding protein 4, adipocyte
chr9_-_123476719 0.63 ENST00000373930.3
multiple EGF-like-domains 9
chr2_+_111880242 0.63 ENST00000393252.3
BCL2-like 11 (apoptosis facilitator)
chr4_+_78079570 0.63 ENST00000509972.1
cyclin G2
chr2_-_208031542 0.62 ENST00000423015.1
Kruppel-like factor 7 (ubiquitous)
chr3_-_65583561 0.62 ENST00000460329.2
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr7_+_128379449 0.62 ENST00000479257.1
calumenin
chr2_-_70475730 0.62 ENST00000445587.1
ENST00000433529.2
ENST00000415783.2
TIA1 cytotoxic granule-associated RNA binding protein
chr20_-_17662705 0.61 ENST00000455029.2
ribosome binding protein 1
chr7_-_75368248 0.61 ENST00000434438.2
ENST00000336926.6
huntingtin interacting protein 1
chr6_-_11232891 0.61 ENST00000379433.5
ENST00000379446.5
neural precursor cell expressed, developmentally down-regulated 9
chr18_-_53177984 0.61 ENST00000543082.1
transcription factor 4
chr18_+_6729698 0.60 ENST00000383472.4
Rho GTPase activating protein 28
chr6_+_89790459 0.60 ENST00000369472.1
proline-rich nuclear receptor coactivator 1
chr8_+_11660227 0.59 ENST00000443614.2
ENST00000525900.1
farnesyl-diphosphate farnesyltransferase 1
chrX_+_84498989 0.59 ENST00000395402.1
zinc finger protein 711
chr4_+_54243917 0.59 ENST00000507166.1
factor interacting with PAPOLA and CPSF1
chr8_-_38325219 0.57 ENST00000533668.1
ENST00000413133.2
ENST00000397108.4
ENST00000526742.1
ENST00000525001.1
ENST00000425967.3
ENST00000529552.1
ENST00000397113.2
fibroblast growth factor receptor 1
chr17_-_76713100 0.57 ENST00000585509.1
cytohesin 1
chr18_+_42260861 0.57 ENST00000282030.5
SET binding protein 1
chr7_+_77167376 0.56 ENST00000435495.2
protein tyrosine phosphatase, non-receptor type 12
chrX_+_84499038 0.56 ENST00000373165.3
zinc finger protein 711
chr12_+_110011571 0.55 ENST00000539696.1
ENST00000228510.3
ENST00000392727.3
mevalonate kinase
chr5_-_131826457 0.55 ENST00000437654.1
ENST00000245414.4
interferon regulatory factor 1
chr3_+_25469802 0.55 ENST00000330688.4
retinoic acid receptor, beta
chr4_-_110723335 0.54 ENST00000394634.2
complement factor I
chr5_+_140797296 0.52 ENST00000398594.2
protocadherin gamma subfamily B, 7
chr2_+_54683419 0.52 ENST00000356805.4
spectrin, beta, non-erythrocytic 1
chr5_-_39425222 0.52 ENST00000320816.6
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr4_-_110723134 0.51 ENST00000510800.1
ENST00000512148.1
complement factor I
chr17_-_39728303 0.51 ENST00000588431.1
ENST00000246662.4
keratin 9
chrX_+_41192595 0.51 ENST00000399959.2
DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
chr12_-_110011288 0.50 ENST00000540016.1
ENST00000266839.5
methylmalonic aciduria (cobalamin deficiency) cblB type
chr11_+_128563652 0.50 ENST00000527786.2
Fli-1 proto-oncogene, ETS transcription factor
chr5_+_140602904 0.49 ENST00000515856.2
ENST00000239449.4
protocadherin beta 14
chr19_+_8455200 0.48 ENST00000601897.1
ENST00000594216.1
RAB11B, member RAS oncogene family
chr7_-_22233442 0.48 ENST00000401957.2
Rap guanine nucleotide exchange factor (GEF) 5
chr20_-_17662878 0.48 ENST00000377813.1
ENST00000377807.2
ENST00000360807.4
ENST00000398782.2
ribosome binding protein 1
chr14_-_53019211 0.47 ENST00000557374.1
ENST00000281741.4
thioredoxin domain containing 16
chr2_-_70475586 0.47 ENST00000416149.2
TIA1 cytotoxic granule-associated RNA binding protein
chr2_+_217498105 0.47 ENST00000233809.4
insulin-like growth factor binding protein 2, 36kDa
chrX_-_2418596 0.47 ENST00000381218.3
zinc finger, BED-type containing 1
chr2_+_109271481 0.47 ENST00000542845.1
ENST00000393314.2
LIM and senescent cell antigen-like domains 1
chr8_+_11660120 0.46 ENST00000220584.4
farnesyl-diphosphate farnesyltransferase 1
chr2_+_208576259 0.46 ENST00000392209.3
cyclin Y-like 1
chr2_-_175629135 0.46 ENST00000409542.1
ENST00000409219.1
cholinergic receptor, nicotinic, alpha 1 (muscle)
chr5_-_39425068 0.46 ENST00000515700.1
ENST00000339788.6
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr9_-_74979420 0.46 ENST00000343431.2
ENST00000376956.3
zinc finger, AN1-type domain 5
chr9_+_116263639 0.46 ENST00000343817.5
regulator of G-protein signaling 3
chrX_+_135579238 0.45 ENST00000535601.1
ENST00000448450.1
ENST00000425695.1
HIV-1 Tat specific factor 1
chr11_-_126138808 0.45 ENST00000332118.6
ENST00000532259.1
signal recognition particle receptor (docking protein)
chr3_+_44690211 0.44 ENST00000396056.2
ENST00000432115.2
ENST00000415571.2
ENST00000399560.2
ENST00000296092.3
ENST00000542250.1
ENST00000453164.1
zinc finger protein 35
chr1_+_66458072 0.44 ENST00000423207.2
phosphodiesterase 4B, cAMP-specific
chr5_-_39425290 0.44 ENST00000545653.1
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr11_-_77531752 0.44 ENST00000440064.2
ENST00000528095.1
remodeling and spacing factor 1
chr15_-_52944231 0.44 ENST00000546305.2
family with sequence similarity 214, member A
chr3_+_25469724 0.44 ENST00000437042.2
retinoic acid receptor, beta
chr6_+_89790490 0.44 ENST00000336032.3
proline-rich nuclear receptor coactivator 1
chr1_-_93645818 0.43 ENST00000370280.1
ENST00000479918.1
transmembrane emp24 protein transport domain containing 5
chr14_-_88459503 0.43 ENST00000393568.4
ENST00000261304.2
galactosylceramidase
chr1_+_12834984 0.43 ENST00000357726.4
PRAME family member 12
chr9_+_116263778 0.43 ENST00000394646.3
regulator of G-protein signaling 3
chr15_-_50411412 0.42 ENST00000284509.6
ATPase, class I, type 8B, member 4
chr4_+_71570430 0.42 ENST00000417478.2
RUN and FYVE domain containing 3
chr1_+_8378140 0.41 ENST00000377479.2
solute carrier family 45, member 1
chr19_-_10491130 0.41 ENST00000530829.1
ENST00000529370.1
tyrosine kinase 2
chr12_-_71003568 0.41 ENST00000547715.1
ENST00000451516.2
ENST00000538708.1
ENST00000550857.1
ENST00000261266.5
protein tyrosine phosphatase, receptor type, B
chr3_-_88108212 0.41 ENST00000482016.1
CGG triplet repeat binding protein 1
chr5_-_141338627 0.40 ENST00000231484.3
protocadherin 12
chr5_+_138677515 0.40 ENST00000265192.4
ENST00000511706.1
poly(A) binding protein interacting protein 2
chr12_-_31479107 0.40 ENST00000542983.1
family with sequence similarity 60, member A
chr7_+_116312411 0.40 ENST00000456159.1
ENST00000397752.3
ENST00000318493.6
met proto-oncogene
chr22_-_19512893 0.39 ENST00000403084.1
ENST00000413119.2
claudin 5
chr19_+_48972459 0.39 ENST00000427476.1
cytohesin 2
chr16_+_2083265 0.38 ENST00000565855.1
ENST00000566198.1
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
chr8_-_38326139 0.38 ENST00000335922.5
ENST00000532791.1
ENST00000397091.5
fibroblast growth factor receptor 1
chr19_+_8455077 0.38 ENST00000328024.6
RAB11B, member RAS oncogene family
chr4_-_175204765 0.38 ENST00000513696.1
ENST00000503293.1
F-box protein 8
chr10_+_6244829 0.38 ENST00000317350.4
ENST00000379785.1
ENST00000379782.3
ENST00000360521.2
ENST00000379775.4
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr15_+_84115868 0.38 ENST00000427482.2
SH3-domain GRB2-like 3
chr15_+_85923797 0.37 ENST00000559362.1
A kinase (PRKA) anchor protein 13
chr11_-_10829851 0.37 ENST00000532082.1
eukaryotic translation initiation factor 4 gamma, 2
chr1_+_24286287 0.37 ENST00000334351.7
ENST00000374468.1
proline-rich nuclear receptor coactivator 2
chr1_+_156119466 0.37 ENST00000414683.1
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr16_+_3068393 0.36 ENST00000573001.1
tumor necrosis factor receptor superfamily, member 12A
chr7_+_134464376 0.36 ENST00000454108.1
ENST00000361675.2
caldesmon 1
chr16_+_3704822 0.35 ENST00000414110.2
deoxyribonuclease I
chr10_-_81205373 0.35 ENST00000372336.3
zinc finger, CCHC domain containing 24
chr5_+_140739537 0.35 ENST00000522605.1
protocadherin gamma subfamily B, 2
chr1_-_153643442 0.35 ENST00000368681.1
ENST00000361891.4
interleukin enhancer binding factor 2
chr11_+_63953587 0.34 ENST00000305218.4
ENST00000538945.1
stress-induced-phosphoprotein 1
chr7_+_128379346 0.34 ENST00000535011.2
ENST00000542996.2
ENST00000535623.1
ENST00000538546.1
ENST00000249364.4
ENST00000449187.2
calumenin
chr10_+_97803151 0.34 ENST00000403870.3
ENST00000265992.5
ENST00000465148.2
ENST00000534974.1
cyclin J
chr5_+_140729649 0.34 ENST00000523390.1
protocadherin gamma subfamily B, 1
chr4_+_113152978 0.34 ENST00000309703.6
adaptor-related protein complex 1 associated regulatory protein
chr4_-_2264015 0.33 ENST00000337190.2
MAX dimerization protein 4
chr4_+_154125565 0.33 ENST00000338700.5
tripartite motif containing 2
chr4_+_54243798 0.33 ENST00000337488.6
ENST00000358575.5
ENST00000507922.1
factor interacting with PAPOLA and CPSF1
chr14_-_71276211 0.33 ENST00000381250.4
ENST00000555993.2
mitogen-activated protein kinase kinase kinase 9
chr7_+_128349106 0.33 ENST00000485070.1
family with sequence similarity 71, member F1
chr2_+_54198210 0.33 ENST00000607452.1
ENST00000422521.2
acylphosphatase 2, muscle type
chr4_+_78078304 0.33 ENST00000316355.5
ENST00000354403.5
ENST00000502280.1
cyclin G2
chr1_+_33722080 0.32 ENST00000483388.1
ENST00000539719.1
zinc finger protein 362
chr9_-_99064386 0.32 ENST00000375262.2
hydroxysteroid (17-beta) dehydrogenase 3
chr1_-_21503337 0.32 ENST00000400422.1
ENST00000602326.1
ENST00000411888.1
ENST00000438975.1
eukaryotic translation initiation factor 4 gamma, 3
chr16_-_25026641 0.32 ENST00000289968.6
ENST00000303665.5
ENST00000455311.2
ENST00000441763.2
Rho GTPase activating protein 17
chr12_+_49761147 0.32 ENST00000549298.1
spermatogenesis associated, serine-rich 2
chr1_-_182641367 0.32 ENST00000508450.1
regulator of G-protein signaling 8
chr14_+_102276192 0.31 ENST00000557714.1
protein phosphatase 2, regulatory subunit B', gamma
chr17_+_26646121 0.31 ENST00000226230.6
transmembrane protein 97
chr19_+_45504688 0.31 ENST00000221452.8
ENST00000540120.1
ENST00000505236.1
v-rel avian reticuloendotheliosis viral oncogene homolog B
chr4_+_113152881 0.31 ENST00000274000.5
adaptor-related protein complex 1 associated regulatory protein
chr2_-_175629164 0.31 ENST00000409323.1
ENST00000261007.5
ENST00000348749.5
cholinergic receptor, nicotinic, alpha 1 (muscle)
chr1_+_228337553 0.31 ENST00000366714.2
gap junction protein, gamma 2, 47kDa
chr9_-_72287191 0.31 ENST00000265381.4
amyloid beta (A4) precursor protein-binding, family A, member 1
chr18_-_44497308 0.31 ENST00000585916.1
ENST00000324794.7
ENST00000545673.1
protein inhibitor of activated STAT, 2
chrX_+_129473859 0.30 ENST00000424447.1
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr5_+_140593509 0.30 ENST00000341948.4
protocadherin beta 13
chr14_-_91884150 0.30 ENST00000553403.1
coiled-coil domain containing 88C
chr12_-_49075941 0.30 ENST00000553086.1
ENST00000548304.1
KAT8 regulatory NSL complex subunit 2
chr1_-_119530428 0.30 ENST00000369429.3
T-box 15
chr9_-_73483958 0.30 ENST00000377101.1
ENST00000377106.1
ENST00000360823.2
ENST00000377105.1
transient receptor potential cation channel, subfamily M, member 3
chr12_-_91546926 0.29 ENST00000550758.1
decorin
chr2_-_240322643 0.29 ENST00000345617.3
histone deacetylase 4
chr3_-_101232019 0.29 ENST00000394095.2
ENST00000394091.1
ENST00000394094.2
ENST00000358203.3
ENST00000348610.3
ENST00000314261.7
SUMO1/sentrin specific peptidase 7
chr14_-_91884115 0.29 ENST00000389857.6
coiled-coil domain containing 88C
chr18_-_34408902 0.29 ENST00000593035.1
ENST00000383056.3
ENST00000588909.1
ENST00000590337.1
tubulin polyglutamylase complex subunit 2
chr19_+_13906250 0.29 ENST00000254323.2
zinc finger, SWIM-type containing 4
chr15_-_34659349 0.29 ENST00000314891.6
lysophosphatidylcholine acyltransferase 4
chr1_+_33116765 0.29 ENST00000544435.1
ENST00000373485.1
ENST00000458695.2
ENST00000490500.1
ENST00000445722.2
retinoblastoma binding protein 4
chrX_+_70503037 0.29 ENST00000535149.1
non-POU domain containing, octamer-binding
chr12_+_69979210 0.29 ENST00000544368.2
chaperonin containing TCP1, subunit 2 (beta)
chr19_-_44100275 0.29 ENST00000422989.1
ENST00000598324.1
immunity-related GTPase family, Q
chr10_+_69644404 0.29 ENST00000212015.6
sirtuin 1
chr2_+_170590321 0.28 ENST00000392647.2
kelch-like family member 23
chr7_+_28452130 0.28 ENST00000357727.2
cAMP responsive element binding protein 5
chr12_+_53443963 0.28 ENST00000546602.1
ENST00000552570.1
ENST00000549700.1
tensin like C1 domain containing phosphatase (tensin 2)
chr14_-_73493784 0.28 ENST00000553891.1
zinc finger, FYVE domain containing 1
chr1_+_25071848 0.28 ENST00000374379.4
chloride intracellular channel 4
chr11_-_69519410 0.28 ENST00000294312.3
fibroblast growth factor 19
chr11_+_34073269 0.27 ENST00000389645.3
cell cycle associated protein 1
chr17_+_67498538 0.27 ENST00000589647.1
mitogen-activated protein kinase kinase 6
chr5_+_140557371 0.27 ENST00000239444.2
protocadherin beta 8

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX9

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.6 1.7 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.6 1.7 GO:2000830 vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.4 1.4 GO:0035026 leading edge cell differentiation(GO:0035026)
0.3 0.9 GO:0070668 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.3 0.9 GO:0035283 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.3 0.8 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.3 3.0 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.2 0.7 GO:0051086 chaperone mediated protein folding independent of cofactor(GO:0051086)
0.2 0.9 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.2 0.9 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.2 0.6 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.2 0.6 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.2 1.1 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.2 0.6 GO:0060139 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.2 0.6 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.2 3.3 GO:2000586 regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586)
0.2 1.0 GO:0009099 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.2 0.5 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.2 0.6 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.2 1.4 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.7 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1 0.5 GO:0035740 CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.1 0.7 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.1 0.5 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.1 1.8 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 0.5 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.1 0.2 GO:1900222 negative regulation of beta-amyloid clearance(GO:1900222)
0.1 1.1 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.1 1.5 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.1 1.0 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 1.9 GO:0071397 cellular response to cholesterol(GO:0071397)
0.1 0.3 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.1 0.3 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 0.3 GO:2000417 negative regulation of eosinophil migration(GO:2000417)
0.1 0.3 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.1 0.9 GO:0045054 constitutive secretory pathway(GO:0045054)
0.1 0.8 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.1 0.2 GO:1904048 regulation of spontaneous neurotransmitter secretion(GO:1904048)
0.1 0.9 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 0.7 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.1 1.0 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 0.4 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.1 0.2 GO:1990108 protein linear deubiquitination(GO:1990108)
0.1 0.3 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 1.9 GO:0016578 histone deubiquitination(GO:0016578)
0.1 0.4 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.2 GO:0042040 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.1 1.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 0.2 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.1 0.3 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.1 0.4 GO:0061370 testosterone biosynthetic process(GO:0061370)
0.1 0.2 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.1 0.4 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.1 0.8 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 0.3 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.1 0.1 GO:0003192 mitral valve formation(GO:0003192)
0.1 0.3 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 1.4 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.1 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0 1.2 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 1.2 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.2 GO:1904382 protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.0 0.2 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0 0.2 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.4 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.3 GO:0070858 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.0 1.3 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 1.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.3 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.0 0.1 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.0 0.4 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.4 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.0 0.3 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.6 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.3 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.1 GO:2000584 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.0 0.1 GO:1904647 response to rotenone(GO:1904647)
0.0 1.0 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.4 GO:0010226 response to lithium ion(GO:0010226)
0.0 0.0 GO:0035787 cell migration involved in kidney development(GO:0035787)
0.0 1.3 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.3 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.3 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 0.3 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 0.1 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.0 0.3 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.6 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.3 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.2 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0 0.4 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.3 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528) positive regulation of sarcomere organization(GO:0060298)
0.0 0.2 GO:0038031 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 0.3 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0 0.9 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 2.3 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.2 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.3 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.0 GO:2001187 positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.0 0.1 GO:0030035 microspike assembly(GO:0030035)
0.0 0.3 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:0009597 detection of virus(GO:0009597)
0.0 0.1 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.4 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.1 GO:0002424 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) T-helper 1 cell activation(GO:0035711)
0.0 0.3 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.1 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.7 GO:0006536 glutamate metabolic process(GO:0006536)
0.0 1.3 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.2 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.3 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0 0.3 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.0 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 1.7 GO:2000257 regulation of complement activation(GO:0030449) regulation of protein activation cascade(GO:2000257)
0.0 0.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.2 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.3 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.0 0.1 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.1 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.6 GO:0031648 protein destabilization(GO:0031648)
0.0 0.5 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 0.9 GO:0055092 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.3 1.3 GO:0030934 anchoring collagen complex(GO:0030934)
0.2 1.8 GO:0097165 nuclear stress granule(GO:0097165)
0.2 1.4 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.5 GO:0033186 CAF-1 complex(GO:0033186)
0.1 1.9 GO:0000124 SAGA complex(GO:0000124)
0.1 1.2 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 1.8 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 0.3 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 0.5 GO:0032437 cuticular plate(GO:0032437)
0.1 1.0 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 0.3 GO:0031213 RSF complex(GO:0031213)
0.1 0.2 GO:0097447 dendritic tree(GO:0097447)
0.1 0.2 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.1 0.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.6 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 0.3 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 0.3 GO:0005899 insulin receptor complex(GO:0005899)
0.1 1.0 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 0.7 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.7 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 3.4 GO:0002102 podosome(GO:0002102)
0.0 1.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.5 GO:0030478 actin cap(GO:0030478)
0.0 0.2 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.0 0.2 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.0 0.2 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.7 GO:0097386 glial cell projection(GO:0097386)
0.0 0.8 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.3 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.7 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.3 GO:0042382 paraspeckles(GO:0042382)
0.0 0.3 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.3 GO:0000322 storage vacuole(GO:0000322)
0.0 0.6 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.9 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.1 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.4 GO:0071437 invadopodium(GO:0071437)
0.0 0.3 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.8 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 1.7 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.4 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.4 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 1.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.4 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 1.7 GO:0005604 basement membrane(GO:0005604)
0.0 0.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.3 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.2 GO:0033270 paranode region of axon(GO:0033270)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.3 0.9 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.3 1.1 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.2 0.7 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.2 1.3 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.2 1.5 GO:0016403 dimethylargininase activity(GO:0016403)
0.2 2.7 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.2 0.6 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.2 1.0 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.2 0.6 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.2 0.9 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.7 GO:0047820 D-glutamate cyclase activity(GO:0047820)
0.1 0.8 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 1.7 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 1.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1 0.5 GO:0004803 transposase activity(GO:0004803)
0.1 1.2 GO:0033592 RNA strand annealing activity(GO:0033592)
0.1 0.3 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.1 0.4 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.1 0.3 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 1.6 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 1.9 GO:0070402 NADPH binding(GO:0070402)
0.1 0.3 GO:0043398 HLH domain binding(GO:0043398)
0.1 1.6 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 0.4 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.1 0.4 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1 1.8 GO:0008143 poly(A) binding(GO:0008143)
0.1 0.8 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 0.2 GO:0061598 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.1 0.3 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.1 1.1 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.2 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 1.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.3 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 0.2 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.6 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 0.6 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 1.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.5 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.3 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.0 0.5 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 1.0 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.0 1.2 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.3 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.3 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.8 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.4 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.9 GO:0031489 myosin V binding(GO:0031489)
0.0 0.5 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 1.1 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.2 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 1.7 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.7 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.2 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 1.1 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 1.6 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 2.1 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.6 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.8 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.2 GO:0000182 rDNA binding(GO:0000182)
0.0 0.3 GO:0043996 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.3 GO:0070628 proteasome binding(GO:0070628)
0.0 0.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0035473 high-density lipoprotein particle binding(GO:0008035) lipase binding(GO:0035473)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.2 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.1 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.5 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.5 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.6 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.6 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.2 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.3 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.6 GO:0042169 SH2 domain binding(GO:0042169)
0.0 1.1 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.7 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.5 GO:0051393 alpha-actinin binding(GO:0051393)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 0.1 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.4 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.6 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.5 PID FOXO PATHWAY FoxO family signaling
0.0 1.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.7 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.2 PID MYC PATHWAY C-MYC pathway
0.0 1.0 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.7 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.8 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 1.9 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.2 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.8 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 1.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.4 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.0 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.9 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.5 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.3 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.5 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.2 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.6 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.2 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.4 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.6 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.6 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.7 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.3 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.4 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.8 PID AP1 PATHWAY AP-1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 0.3 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.1 1.7 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.1 1.4 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 1.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 0.3 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.1 1.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.6 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.8 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.9 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 1.0 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.8 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.4 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.4 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.6 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.5 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.7 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.3 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 1.0 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.3 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.5 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 1.7 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events