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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for SP100

Z-value: 1.10

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Transcription factors associated with SP100

Gene Symbol Gene ID Gene Info
ENSG00000067066.12 SP100 nuclear antigen

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SP100hg19_v2_chr2_+_231280908_231280945-0.716.9e-05Click!

Activity profile of SP100 motif

Sorted Z-values of SP100 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_41540160 7.09 ENST00000503057.1
ENST00000511496.1
LIM and calponin homology domains 1
chr4_+_156588350 6.32 ENST00000296518.7
guanylate cyclase 1, soluble, alpha 3
chr4_+_156588249 6.20 ENST00000393832.3
guanylate cyclase 1, soluble, alpha 3
chr4_+_156588115 6.02 ENST00000455639.2
guanylate cyclase 1, soluble, alpha 3
chr4_+_156588806 6.01 ENST00000513574.1
guanylate cyclase 1, soluble, alpha 3
chr3_+_8543561 5.04 ENST00000397386.3
LIM and cysteine-rich domains 1
chr1_+_78511586 3.95 ENST00000370759.3
GIPC PDZ domain containing family, member 2
chr17_+_39394250 3.77 ENST00000254072.6
keratin associated protein 9-8
chr1_+_47489240 2.94 ENST00000371901.3
cytochrome P450, family 4, subfamily X, polypeptide 1
chr8_-_93029865 2.64 ENST00000422361.2
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr3_+_8543393 2.63 ENST00000157600.3
ENST00000415597.1
ENST00000535732.1
LIM and cysteine-rich domains 1
chr2_+_38893208 2.44 ENST00000410063.1
galactose mutarotase (aldose 1-epimerase)
chr10_-_91174215 2.03 ENST00000371837.1
lipase A, lysosomal acid, cholesterol esterase
chr4_-_90757364 1.99 ENST00000508895.1
synuclein, alpha (non A4 component of amyloid precursor)
chr1_+_90098606 1.99 ENST00000370454.4
leucine rich repeat containing 8 family, member C
chr7_-_91764108 1.96 ENST00000450723.1
cytochrome P450, family 51, subfamily A, polypeptide 1
chr3_-_18466026 1.89 ENST00000417717.2
SATB homeobox 1
chr12_+_93964158 1.88 ENST00000549206.1
suppressor of cytokine signaling 2
chr14_-_30396948 1.86 ENST00000331968.5
protein kinase D1
chr10_+_35416223 1.53 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
cAMP responsive element modulator
chr3_+_8543533 1.52 ENST00000454244.1
LIM and cysteine-rich domains 1
chr14_+_38677123 1.51 ENST00000267377.2
somatostatin receptor 1
chr7_-_120498357 1.47 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
tetraspanin 12
chr19_+_52901094 1.33 ENST00000391788.2
ENST00000436397.1
ENST00000391787.2
ENST00000360465.3
ENST00000494167.2
ENST00000493272.1
zinc finger protein 528
chr12_-_6772303 1.33 ENST00000396807.4
ENST00000446105.2
ENST00000341550.4
inhibitor of growth family, member 4
chr12_+_10365404 1.28 ENST00000266458.5
ENST00000421801.2
ENST00000544284.1
ENST00000545047.1
ENST00000543602.1
ENST00000545887.1
GABA(A) receptor-associated protein like 1
chr12_-_42877726 1.25 ENST00000548696.1
prickle homolog 1 (Drosophila)
chr8_-_9008206 1.25 ENST00000310455.3
protein phosphatase 1, regulatory subunit 3B
chr13_+_114462193 1.22 ENST00000375353.3
transmembrane protein 255B
chr1_+_109102652 1.22 ENST00000370035.3
ENST00000405454.1
family with sequence similarity 102, member B
chr2_+_189156586 1.20 ENST00000409830.1
GULP, engulfment adaptor PTB domain containing 1
chrX_-_10588459 1.13 ENST00000380782.2
midline 1 (Opitz/BBB syndrome)
chr18_+_3466248 1.12 ENST00000581029.1
ENST00000581442.1
ENST00000579007.1
RP11-838N2.4
chr13_+_114567131 1.12 ENST00000608651.1
GAS6 antisense RNA 2 (head to head)
chr1_+_63989004 1.09 ENST00000371088.4
EF-hand calcium binding domain 7
chr8_-_19459993 1.05 ENST00000454498.2
ENST00000520003.1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr14_-_75530693 1.05 ENST00000555135.1
ENST00000357971.3
ENST00000553302.1
ENST00000555694.1
ENST00000238618.3
acylphosphatase 1, erythrocyte (common) type
chr19_+_32896646 1.05 ENST00000392250.2
dpy-19-like 3 (C. elegans)
chrX_-_10588595 1.04 ENST00000423614.1
ENST00000317552.4
midline 1 (Opitz/BBB syndrome)
chr9_-_126030817 1.04 ENST00000348403.5
ENST00000447404.2
ENST00000360998.3
spermatid perinuclear RNA binding protein
chr18_-_52989217 1.01 ENST00000570287.2
transcription factor 4
chr6_+_42847649 0.98 ENST00000424341.2
ENST00000602561.1
ribosomal protein L7-like 1
chr6_-_41888843 0.97 ENST00000434077.1
ENST00000409312.1
mediator complex subunit 20
chr18_-_52989525 0.95 ENST00000457482.3
transcription factor 4
chr4_-_123843597 0.95 ENST00000510735.1
ENST00000304430.5
nudix (nucleoside diphosphate linked moiety X)-type motif 6
chr4_-_54232144 0.93 ENST00000388940.4
ENST00000503450.1
ENST00000401642.3
sec1 family domain containing 2
chr11_+_31531291 0.92 ENST00000350638.5
ENST00000379163.5
ENST00000395934.2
elongator acetyltransferase complex subunit 4
chr11_-_31531121 0.89 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr7_-_108168580 0.88 ENST00000453085.1
patatin-like phospholipase domain containing 8
chr17_+_20483037 0.87 ENST00000399044.1
CMT1A duplicated region transcript 15-like 2
chr10_-_18948156 0.86 ENST00000414939.1
ENST00000449529.1
ENST00000456217.1
ENST00000444660.1
ARL5B antisense RNA 1
chr22_-_29107919 0.86 ENST00000434810.1
ENST00000456369.1
checkpoint kinase 2
chr5_-_76383133 0.86 ENST00000255198.2
zinc finger, BED-type containing 3
chr11_+_7626950 0.85 ENST00000530181.1
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chrX_-_99891796 0.85 ENST00000373020.4
tetraspanin 6
chr14_+_45605157 0.83 ENST00000542564.2
Fanconi anemia, complementation group M
chr11_-_2162468 0.82 ENST00000434045.2
insulin-like growth factor 2 (somatomedin A)
chr7_-_156685841 0.82 ENST00000354505.4
ENST00000540390.1
limb development membrane protein 1
chr11_-_77790865 0.82 ENST00000534029.1
ENST00000525085.1
ENST00000527806.1
ENST00000528164.1
ENST00000528251.1
ENST00000530054.1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa
NDUFC2-KCTD14 readthrough
chr6_-_2962331 0.82 ENST00000380524.1
serpin peptidase inhibitor, clade B (ovalbumin), member 6
chr10_+_18948311 0.80 ENST00000377275.3
ADP-ribosylation factor-like 5B
chr20_-_36156293 0.79 ENST00000373537.2
ENST00000414542.2
bladder cancer associated protein
chr19_+_58281014 0.79 ENST00000391702.3
ENST00000598885.1
ENST00000598183.1
ENST00000396154.2
ENST00000599802.1
ENST00000396150.4
zinc finger protein 586
chr16_-_68034470 0.79 ENST00000412757.2
dipeptidase 2
chr17_+_19552036 0.79 ENST00000581518.1
ENST00000395575.2
ENST00000584332.2
ENST00000339618.4
ENST00000579855.1
aldehyde dehydrogenase 3 family, member A2
chr16_-_28303360 0.77 ENST00000501520.1
RP11-57A19.2
chr12_+_104324112 0.77 ENST00000299767.5
heat shock protein 90kDa beta (Grp94), member 1
chr20_-_36156125 0.76 ENST00000397135.1
ENST00000397137.1
bladder cancer associated protein
chr6_+_158957431 0.76 ENST00000367090.3
transmembrane protein 181
chr2_+_177134134 0.76 ENST00000249442.6
ENST00000392529.2
ENST00000443241.1
metaxin 2
chr17_-_67057047 0.75 ENST00000495634.1
ENST00000453985.2
ENST00000585714.1
ATP-binding cassette, sub-family A (ABC1), member 9
chr13_+_50656307 0.75 ENST00000378180.4
deleted in lymphocytic leukemia 1 (non-protein coding)
chr22_+_32455111 0.75 ENST00000543737.1
solute carrier family 5 (sodium/glucose cotransporter), member 1
chr17_-_67057114 0.74 ENST00000370732.2
ATP-binding cassette, sub-family A (ABC1), member 9
chr5_+_140514782 0.74 ENST00000231134.5
protocadherin beta 5
chr2_+_179149636 0.74 ENST00000409631.1
oxysterol binding protein-like 6
chr20_-_33732952 0.73 ENST00000541621.1
ER degradation enhancer, mannosidase alpha-like 2
chr8_+_75262612 0.72 ENST00000220822.7
ganglioside induced differentiation associated protein 1
chr3_-_27764190 0.71 ENST00000537516.1
eomesodermin
chr1_+_104068312 0.71 ENST00000524631.1
ENST00000531883.1
ENST00000533099.1
ENST00000527062.1
RNA-binding region (RNP1, RRM) containing 3
chr7_+_139025875 0.70 ENST00000297534.6
chromosome 7 open reading frame 55
chr5_-_178054014 0.70 ENST00000520957.1
CDC-like kinase 4
chr3_+_159557637 0.70 ENST00000445224.2
schwannomin interacting protein 1
chr5_-_93447333 0.70 ENST00000395965.3
ENST00000505869.1
ENST00000509163.1
family with sequence similarity 172, member A
chr6_-_86303833 0.69 ENST00000505648.1
sorting nexin 14
chr9_-_33264557 0.69 ENST00000473781.1
ENST00000488499.1
BCL2-associated athanogene
chr11_-_77791156 0.69 ENST00000281031.4
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa
chr14_-_106471723 0.68 ENST00000390595.2
immunoglobulin heavy variable 1-3
chrX_-_77395186 0.68 ENST00000341864.5
TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
chr6_-_86303523 0.68 ENST00000513865.1
ENST00000369627.2
ENST00000514419.1
ENST00000509338.1
ENST00000314673.3
ENST00000346348.3
sorting nexin 14
chr11_+_121461097 0.67 ENST00000527934.1
sortilin-related receptor, L(DLR class) A repeats containing
chr19_+_48281928 0.66 ENST00000593892.1
selenoprotein W, 1
chr2_-_183106641 0.66 ENST00000346717.4
phosphodiesterase 1A, calmodulin-dependent
chr19_+_48281946 0.66 ENST00000595615.1
selenoprotein W, 1
chr10_+_112327425 0.65 ENST00000361804.4
structural maintenance of chromosomes 3
chr11_-_17410869 0.63 ENST00000528731.1
potassium inwardly-rectifying channel, subfamily J, member 11
chr3_+_122296443 0.63 ENST00000464300.2
poly (ADP-ribose) polymerase family, member 15
chr2_+_24346324 0.63 ENST00000407625.1
ENST00000420135.2
family with sequence similarity 228, member B
chr11_+_6947720 0.62 ENST00000414517.2
zinc finger protein 215
chr1_+_196621002 0.62 ENST00000367429.4
ENST00000439155.2
complement factor H
chrX_+_70586140 0.62 ENST00000276072.3
TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
chr21_-_27462351 0.61 ENST00000448850.1
amyloid beta (A4) precursor protein
chr2_-_152118352 0.60 ENST00000331426.5
RNA binding motif protein 43
chr8_+_110552831 0.60 ENST00000530629.1
estrogen receptor binding site associated, antigen, 9
chr10_-_38146510 0.59 ENST00000395867.3
zinc finger protein 248
chr10_+_6130966 0.58 ENST00000437845.2
ENST00000432931.1
RNA binding motif protein 17
chrX_-_50386648 0.58 ENST00000460112.3
shroom family member 4
chr10_+_74927875 0.58 ENST00000242505.6
family with sequence similarity 149, member B1
chr9_-_135230336 0.58 ENST00000224140.5
ENST00000372169.2
ENST00000393220.1
senataxin
chr7_+_142985308 0.58 ENST00000310447.5
caspase 2, apoptosis-related cysteine peptidase
chr12_+_110011571 0.58 ENST00000539696.1
ENST00000228510.3
ENST00000392727.3
mevalonate kinase
chr3_-_150996239 0.58 ENST00000309170.3
purinergic receptor P2Y, G-protein coupled, 14
chr19_+_44556158 0.57 ENST00000434772.3
ENST00000585552.1
zinc finger protein 223
chr1_-_87379785 0.57 ENST00000401030.3
ENST00000370554.1
Homo sapiens 15 kDa selenoprotein (SEP15), transcript variant 2, mRNA.
chr6_-_13486369 0.57 ENST00000558378.1
AL583828.1
chr9_-_98269481 0.56 ENST00000418258.1
ENST00000553011.1
ENST00000551845.1
patched 1
chr7_+_2443202 0.55 ENST00000258711.6
carbohydrate (chondroitin 4) sulfotransferase 12
chr13_-_97646604 0.55 ENST00000298440.1
ENST00000543457.1
ENST00000541038.1
oxoglutarate (alpha-ketoglutarate) receptor 1
chr15_+_55611128 0.55 ENST00000164305.5
ENST00000539642.1
phosphatidylinositol glycan anchor biosynthesis, class B
chr10_-_74927810 0.55 ENST00000372979.4
ENST00000430082.2
ENST00000454759.2
ENST00000413026.1
ENST00000453402.1
ecdysoneless homolog (Drosophila)
chr16_-_18812746 0.55 ENST00000546206.2
ENST00000562819.1
ENST00000562234.2
ENST00000304414.7
ENST00000567078.2
ADP-ribosylation factor-like 6 interacting protein 1
Uncharacterized protein
chr13_+_32313658 0.54 ENST00000380314.1
ENST00000298386.2
relaxin/insulin-like family peptide receptor 2
chr16_+_68119764 0.54 ENST00000570212.1
ENST00000562926.1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr3_-_187455680 0.54 ENST00000438077.1
B-cell CLL/lymphoma 6
chr4_-_76861392 0.53 ENST00000505594.1
N-acylethanolamine acid amidase
chr10_+_6130946 0.53 ENST00000379888.4
RNA binding motif protein 17
chr1_-_23694794 0.52 ENST00000374608.3
zinc finger protein 436
chr1_-_21503337 0.52 ENST00000400422.1
ENST00000602326.1
ENST00000411888.1
ENST00000438975.1
eukaryotic translation initiation factor 4 gamma, 3
chr1_+_207925391 0.52 ENST00000358170.2
ENST00000354848.1
ENST00000322918.5
ENST00000367042.1
ENST00000367041.1
ENST00000357714.1
ENST00000322875.4
ENST00000367047.1
ENST00000441839.2
ENST00000361067.1
ENST00000360212.2
ENST00000480003.1
CD46 molecule, complement regulatory protein
chr11_-_57282349 0.52 ENST00000528450.1
solute carrier family 43 (amino acid system L transporter), member 1
chr1_-_75198681 0.51 ENST00000370872.3
ENST00000370871.3
ENST00000340866.5
ENST00000370870.1
crystallin, zeta (quinone reductase)
chr16_-_15736881 0.51 ENST00000540441.2
KIAA0430
chr6_+_57182400 0.51 ENST00000607273.1
primase, DNA, polypeptide 2 (58kDa)
chr7_-_156685890 0.51 ENST00000353442.5
limb development membrane protein 1
chr1_+_231473743 0.50 ENST00000295050.7
SprT-like N-terminal domain
chr6_-_116601044 0.50 ENST00000368608.3
TSPY-like 1
chr6_-_41888814 0.50 ENST00000409060.1
ENST00000265350.4
mediator complex subunit 20
chr3_+_111697843 0.49 ENST00000534857.1
ENST00000273359.3
ENST00000494817.1
abhydrolase domain containing 10
chr2_-_20251744 0.49 ENST00000175091.4
lysosomal protein transmembrane 4 alpha
chr17_-_7760779 0.49 ENST00000335155.5
ENST00000575071.1
LSM domain containing 1
chr7_-_40174201 0.49 ENST00000306984.6
M-phase specific PLK1 interacting protein
chr10_+_45495898 0.49 ENST00000298299.3
zinc finger protein 22
chr2_+_48667898 0.49 ENST00000281394.4
ENST00000294952.8
protein phosphatase 1, regulatory subunit 21
chr1_-_165668100 0.48 ENST00000354775.4
aldehyde dehydrogenase 9 family, member A1
chr1_-_21377447 0.48 ENST00000374937.3
ENST00000264211.8
eukaryotic translation initiation factor 4 gamma, 3
chr17_-_36003487 0.48 ENST00000394367.3
ENST00000349699.2
DEAD (Asp-Glu-Ala-Asp) box polypeptide 52
chr1_+_70876926 0.48 ENST00000370938.3
ENST00000346806.2
cystathionase (cystathionine gamma-lyase)
chr12_-_10978957 0.46 ENST00000240619.2
taste receptor, type 2, member 10
chr2_-_211341411 0.46 ENST00000233714.4
ENST00000443314.1
ENST00000441020.3
ENST00000450366.2
ENST00000431941.2
LanC lantibiotic synthetase component C-like 1 (bacterial)
chr19_-_38085633 0.46 ENST00000593133.1
ENST00000590751.1
ENST00000358744.3
ENST00000328550.2
ENST00000451802.2
zinc finger protein 571
chr19_+_35773242 0.46 ENST00000222304.3
hepcidin antimicrobial peptide
chr6_-_127664475 0.46 ENST00000474289.2
ENST00000534442.1
ENST00000368289.2
ENST00000525745.1
ENST00000430841.2
enoyl CoA hydratase domain containing 1
chr17_+_39969183 0.45 ENST00000321562.4
FK506 binding protein 10, 65 kDa
chr14_+_45605127 0.45 ENST00000556036.1
ENST00000267430.5
Fanconi anemia, complementation group M
chr2_+_39103103 0.45 ENST00000340556.6
ENST00000410014.1
ENST00000409665.1
ENST00000409077.2
ENST00000409131.2
MORN repeat containing 2
chr12_+_95867727 0.45 ENST00000323666.5
ENST00000546753.1
methionyl aminopeptidase 2
chr11_+_93474786 0.45 ENST00000331239.4
ENST00000533585.1
ENST00000528099.1
ENST00000354421.3
ENST00000540113.1
ENST00000530620.1
ENST00000527003.1
ENST00000531650.1
ENST00000530279.1
chromosome 11 open reading frame 54
chr2_-_178129551 0.44 ENST00000430047.1
nuclear factor, erythroid 2-like 2
chr6_+_127587755 0.44 ENST00000368314.1
ENST00000476956.1
ENST00000609447.1
ENST00000356799.2
ENST00000477776.1
ENST00000609944.1
ring finger protein 146
chr15_-_90892669 0.44 ENST00000412799.2
GABA(A) receptors associated protein like 3, pseudogene
chr7_+_134671234 0.44 ENST00000436302.2
ENST00000359383.3
ENST00000458078.1
ENST00000435976.2
ENST00000455283.2
ATP/GTP binding protein-like 3
chr2_-_70475730 0.43 ENST00000445587.1
ENST00000433529.2
ENST00000415783.2
TIA1 cytotoxic granule-associated RNA binding protein
chr19_-_9546227 0.43 ENST00000361451.2
ENST00000361151.1
zinc finger protein 266
chr2_+_113403434 0.43 ENST00000272542.3
solute carrier family 20 (phosphate transporter), member 1
chr6_+_32709119 0.43 ENST00000374940.3
major histocompatibility complex, class II, DQ alpha 2
chr4_-_57976544 0.42 ENST00000295666.4
ENST00000537922.1
insulin-like growth factor binding protein 7
chr22_-_39715600 0.42 ENST00000427905.1
ENST00000402527.1
ENST00000216146.4
ribosomal protein L3
chr16_+_10479906 0.42 ENST00000562527.1
ENST00000396560.2
ENST00000396559.1
ENST00000562102.1
ENST00000543967.1
ENST00000569939.1
ENST00000569900.1
activating transcription factor 7 interacting protein 2
chr6_+_31371337 0.42 ENST00000449934.2
ENST00000421350.1
MHC class I polypeptide-related sequence A
chr4_-_170679024 0.42 ENST00000393381.2
chromosome 4 open reading frame 27
chr2_-_113191096 0.42 ENST00000496537.1
ENST00000330575.5
ENST00000302558.3
RANBP2-like and GRIP domain containing 8
chr11_+_65657875 0.41 ENST00000312579.2
coiled-coil domain containing 85B
chr4_-_99064387 0.41 ENST00000295268.3
sperm-tail PG-rich repeat containing 2
chr1_-_204116078 0.41 ENST00000367198.2
ENST00000452983.1
ethanolamine kinase 2
chr11_-_27723158 0.41 ENST00000395980.2
brain-derived neurotrophic factor
chr8_+_75262629 0.41 ENST00000434412.2
ganglioside induced differentiation associated protein 1
chr1_-_87380002 0.40 ENST00000331835.5
Homo sapiens 15 kDa selenoprotein (SEP15), transcript variant 2, mRNA.
chr21_+_40752170 0.40 ENST00000333781.5
ENST00000541890.1
tryptophan rich basic protein
chr9_-_97402413 0.40 ENST00000414122.1
fructose-1,6-bisphosphatase 1
chr12_-_64784471 0.39 ENST00000333722.5
chromosome 12 open reading frame 56
chr17_-_8079648 0.39 ENST00000449985.2
ENST00000532998.1
ENST00000437139.2
ENST00000533070.1
ENST00000316425.5
transmembrane protein 107
chr13_-_31736478 0.39 ENST00000445273.2
heat shock 105kDa/110kDa protein 1
chr17_-_8079632 0.39 ENST00000431792.2
transmembrane protein 107
chr6_+_135502408 0.39 ENST00000341911.5
ENST00000442647.2
ENST00000316528.8
v-myb avian myeloblastosis viral oncogene homolog
chr3_-_156878540 0.39 ENST00000461804.1
cyclin L1
chr19_-_12512062 0.39 ENST00000595766.1
ENST00000430385.3
zinc finger protein 799
chr12_+_96883347 0.39 ENST00000524981.4
ENST00000298953.3
chromosome 12 open reading frame 55
chrX_-_13752675 0.38 ENST00000380579.1
ENST00000458511.2
ENST00000519885.1
ENST00000358231.5
ENST00000518847.1
ENST00000453655.2
ENST00000359680.5
trafficking protein particle complex 2
chr9_+_104296122 0.38 ENST00000389120.3
ring finger protein 20, E3 ubiquitin protein ligase
chr10_-_74385811 0.38 ENST00000603011.1
ENST00000401998.3
ENST00000361114.5
ENST00000604238.1
mitochondrial calcium uptake 1
chr13_-_31736027 0.38 ENST00000380406.5
ENST00000320027.5
ENST00000380405.4
heat shock 105kDa/110kDa protein 1
chr17_-_7761172 0.38 ENST00000333775.5
ENST00000575771.1
LSM domain containing 1
chr8_+_110552337 0.38 ENST00000337573.5
estrogen receptor binding site associated, antigen, 9
chr15_-_26108355 0.38 ENST00000356865.6
ATPase, class V, type 10A
chr2_+_48667983 0.37 ENST00000449090.2
protein phosphatase 1, regulatory subunit 21
chr1_-_63988846 0.37 ENST00000283568.8
ENST00000371092.3
ENST00000271002.10
integrin beta 3 binding protein (beta3-endonexin)
chr5_+_140535577 0.37 ENST00000539533.1
Protocadherin-psi1; Uncharacterized protein
chr5_-_140683612 0.36 ENST00000239451.4
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2
chr5_+_64064748 0.36 ENST00000381070.3
ENST00000508024.1
CWC27 spliceosome-associated protein homolog (S. cerevisiae)
chr6_+_135502466 0.36 ENST00000367814.4
v-myb avian myeloblastosis viral oncogene homolog

Network of associatons between targets according to the STRING database.

First level regulatory network of SP100

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 24.5 GO:0052565 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.6 2.4 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
0.4 2.0 GO:1903284 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.3 8.9 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.3 1.3 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.3 1.3 GO:2000691 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.3 1.5 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.3 0.9 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.3 0.9 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.3 0.5 GO:1903464 negative regulation of mitotic cell cycle DNA replication(GO:1903464)
0.3 1.9 GO:0089700 protein kinase D signaling(GO:0089700)
0.3 1.1 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.3 0.8 GO:0031247 actin rod assembly(GO:0031247)
0.3 0.8 GO:0009405 pathogenesis(GO:0009405)
0.2 0.7 GO:0036511 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.2 0.7 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.2 0.7 GO:1902955 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.2 0.6 GO:0009107 lipoate biosynthetic process(GO:0009107)
0.2 0.6 GO:1990922 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.2 0.6 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.2 0.7 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.2 0.2 GO:1902957 negative regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902957)
0.2 2.2 GO:0035372 protein localization to microtubule(GO:0035372)
0.2 0.5 GO:1990641 cellular response to bile acid(GO:1903413) response to iron ion starvation(GO:1990641)
0.2 0.5 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.1 1.1 GO:1903751 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.1 0.6 GO:0010157 response to chlorate(GO:0010157)
0.1 0.5 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.1 0.4 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.1 0.9 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.1 0.4 GO:0006711 estrogen catabolic process(GO:0006711)
0.1 1.0 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1 1.9 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.6 GO:0036369 transcription factor catabolic process(GO:0036369)
0.1 0.6 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.1 0.5 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.1 0.3 GO:0061566 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.1 0.6 GO:2001166 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.1 0.9 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 0.8 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.1 1.9 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 0.4 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.1 0.7 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.1 1.8 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 0.7 GO:0044789 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.1 0.8 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 0.9 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 1.2 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 0.4 GO:1903788 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.1 0.4 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 0.5 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 0.3 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.1 0.2 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.1 0.6 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 1.3 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.1 0.3 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.1 0.2 GO:0031455 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.1 0.3 GO:2000768 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.1 1.0 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 0.6 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.1 0.8 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.1 0.3 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.1 0.5 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.1 0.2 GO:0060545 regulation of nucleoside transport(GO:0032242) positive regulation of necroptotic process(GO:0060545)
0.1 0.3 GO:1990502 dense core granule maturation(GO:1990502)
0.1 0.2 GO:0030185 nitric oxide transport(GO:0030185)
0.1 0.4 GO:1903352 L-ornithine transmembrane transport(GO:1903352)
0.1 0.4 GO:0051414 response to cortisol(GO:0051414)
0.1 0.2 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.1 0.8 GO:0039532 negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039532)
0.1 0.2 GO:0019085 early viral transcription(GO:0019085)
0.1 0.6 GO:0071316 cellular response to nicotine(GO:0071316)
0.1 2.0 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.1 1.6 GO:0010842 retina layer formation(GO:0010842)
0.1 3.1 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.2 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.3 GO:0036363 transforming growth factor beta activation(GO:0036363)
0.0 0.5 GO:0045591 positive regulation of memory T cell differentiation(GO:0043382) positive regulation of regulatory T cell differentiation(GO:0045591)
0.0 0.4 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:0001694 histamine biosynthetic process(GO:0001694)
0.0 0.5 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.2 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.0 0.6 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.5 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578)
0.0 0.3 GO:0010767 regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010767)
0.0 0.2 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.1 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.0 0.2 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.2 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.0 1.6 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.0 0.9 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.4 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.3 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.7 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.4 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.3 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.4 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 1.1 GO:0071305 cellular response to vitamin D(GO:0071305)
0.0 0.1 GO:0035973 aggrephagy(GO:0035973)
0.0 0.2 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 1.0 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.4 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.2 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 2.1 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.5 GO:1904903 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.2 GO:1902573 positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573)
0.0 0.1 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.4 GO:0016584 nucleosome positioning(GO:0016584)
0.0 2.0 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.0 1.3 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.3 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.3 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.2 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.6 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.2 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.5 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.0 1.5 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.1 GO:2001015 negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.0 0.4 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.1 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
0.0 0.5 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.0 0.1 GO:1903567 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.0 0.3 GO:0005984 disaccharide metabolic process(GO:0005984)
0.0 0.3 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.3 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.8 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.2 GO:0018065 protein-cofactor linkage(GO:0018065)
0.0 0.1 GO:0032445 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.0 0.6 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.3 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 0.3 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.1 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.3 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 3.9 GO:0031424 keratinization(GO:0031424)
0.0 0.4 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.2 GO:0000050 urea cycle(GO:0000050)
0.0 0.2 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.1 GO:0060620 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0 2.0 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 0.6 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.2 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.4 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.0 GO:0034471 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.0 0.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.8 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.7 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.0 0.5 GO:0001556 oocyte maturation(GO:0001556)
0.0 0.4 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 5.3 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 0.2 GO:0015816 glycine transport(GO:0015816)
0.0 0.4 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.3 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.1 GO:0042078 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.3 GO:0006743 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.9 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0 0.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 3.5 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.1 GO:1902570 protein localization to nucleolus(GO:1902570)
0.0 0.1 GO:0090210 vitamin E metabolic process(GO:0042360) regulation of establishment of blood-brain barrier(GO:0090210) negative regulation of establishment of blood-brain barrier(GO:0090212)
0.0 0.1 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 0.1 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.3 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.1 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.5 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.2 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
0.0 0.5 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.0 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408) oxidative stress-induced premature senescence(GO:0090403)
0.0 0.4 GO:0033522 histone H2A ubiquitination(GO:0033522)
0.0 0.3 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 0.2 GO:0042118 endothelial cell activation(GO:0042118)
0.0 1.8 GO:0044070 regulation of anion transport(GO:0044070)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 24.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.4 1.3 GO:0071821 FANCM-MHF complex(GO:0071821)
0.3 0.9 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.7 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.1 1.2 GO:0042587 glycogen granule(GO:0042587)
0.1 0.8 GO:0033503 HULC complex(GO:0033503)
0.1 0.4 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.1 0.5 GO:0002079 inner acrosomal membrane(GO:0002079)
0.1 0.5 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1 0.4 GO:0031213 RSF complex(GO:0031213)
0.1 1.3 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.9 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.4 GO:1990246 uniplex complex(GO:1990246)
0.1 0.3 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 2.0 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.1 0.6 GO:0044294 dendritic growth cone(GO:0044294)
0.1 0.6 GO:0070852 cell body fiber(GO:0070852)
0.1 2.7 GO:0000421 autophagosome membrane(GO:0000421)
0.1 2.0 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.5 GO:0097255 R2TP complex(GO:0097255)
0.1 0.4 GO:0097165 nuclear stress granule(GO:0097165)
0.0 1.0 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 3.8 GO:0045095 keratin filament(GO:0045095)
0.0 0.5 GO:0045179 apical cortex(GO:0045179)
0.0 0.3 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.6 GO:0000124 SAGA complex(GO:0000124)
0.0 0.3 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.7 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.2 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 2.1 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.1 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 0.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 1.1 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.2 GO:0044292 dendrite terminus(GO:0044292)
0.0 4.2 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.1 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 1.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.1 GO:0000799 nuclear condensin complex(GO:0000799)
0.0 1.1 GO:0016592 mediator complex(GO:0016592)
0.0 0.8 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.4 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 1.0 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.1 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.4 GO:0031045 dense core granule(GO:0031045)
0.0 0.8 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 1.7 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.5 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.4 GO:0071141 SMAD protein complex(GO:0071141)
0.0 1.0 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 1.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.0 GO:0030849 autosome(GO:0030849)
0.0 0.1 GO:0042555 MCM complex(GO:0042555)
0.0 0.6 GO:0016460 myosin II complex(GO:0016460)
0.0 7.8 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.8 GO:0031526 brush border membrane(GO:0031526)
0.0 1.1 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 1.6 GO:0043202 lysosomal lumen(GO:0043202)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 24.5 GO:0004383 guanylate cyclase activity(GO:0004383)
0.4 2.0 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.4 1.1 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.3 2.0 GO:0004771 sterol esterase activity(GO:0004771)
0.3 1.9 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.3 1.5 GO:0004994 somatostatin receptor activity(GO:0004994)
0.3 0.8 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.2 0.7 GO:0030626 U12 snRNA binding(GO:0030626)
0.2 0.6 GO:0016992 lipoate synthase activity(GO:0016992) radical SAM enzyme activity(GO:0070283)
0.2 0.6 GO:0001147 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.2 1.0 GO:0003998 acylphosphatase activity(GO:0003998)
0.2 0.7 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.2 0.7 GO:0036033 mediator complex binding(GO:0036033)
0.2 0.6 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.2 0.5 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.2 2.0 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.4 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.1 1.8 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 2.9 GO:0070330 aromatase activity(GO:0070330)
0.1 0.5 GO:0003896 DNA primase activity(GO:0003896)
0.1 2.1 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 0.5 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.1 0.4 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 0.6 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.5 GO:0070404 NADH binding(GO:0070404)
0.1 0.3 GO:0002134 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)
0.1 0.6 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.1 0.7 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.6 GO:0005119 smoothened binding(GO:0005119)
0.1 0.9 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.1 0.6 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.1 0.3 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.1 0.8 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 1.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 1.3 GO:0030957 Tat protein binding(GO:0030957)
0.1 0.9 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.1 1.9 GO:0004697 protein kinase C activity(GO:0004697)
0.1 0.3 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1 0.7 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.1 0.7 GO:0046790 virion binding(GO:0046790)
0.1 0.3 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 0.2 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.1 0.6 GO:0051425 PTB domain binding(GO:0051425)
0.1 0.4 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 0.4 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.3 GO:0032089 NACHT domain binding(GO:0032089)
0.0 0.7 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.3 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 2.2 GO:0032451 demethylase activity(GO:0032451)
0.0 0.2 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.2 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 1.0 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.2 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.4 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.2 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.0 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.6 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 1.4 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.0 1.0 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.0 0.1 GO:0019862 IgA binding(GO:0019862)
0.0 0.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.3 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.0 2.1 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.9 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.5 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 1.8 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.2 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.1 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 11.4 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.3 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.3 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.4 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.4 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.3 GO:0019784 SUMO-specific protease activity(GO:0016929) NEDD8-specific protease activity(GO:0019784)
0.0 0.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.4 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.3 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.5 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.6 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.8 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.7 GO:0005041 low-density lipoprotein receptor activity(GO:0005041) low-density lipoprotein particle binding(GO:0030169)
0.0 0.5 GO:0043295 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.1 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 0.4 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.8 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.5 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 1.4 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.2 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.1 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.3 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.4 GO:0015250 water channel activity(GO:0015250)
0.0 0.3 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.0 0.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 1.0 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.8 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 2.2 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.1 GO:0003955 NAD(P)H dehydrogenase (quinone) activity(GO:0003955)
0.0 0.6 GO:0008198 ferrous iron binding(GO:0008198)
0.0 0.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.7 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.5 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.0 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.0 0.7 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.5 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.4 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.0 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.0 0.5 GO:0001848 complement binding(GO:0001848)
0.0 0.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.1 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.4 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.0 0.1 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 0.1 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.2 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.0 0.4 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.1 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.3 GO:0045505 dynein intermediate chain binding(GO:0045505)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.0 ST GA13 PATHWAY G alpha 13 Pathway
0.0 2.0 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.2 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.9 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 1.5 PID ATM PATHWAY ATM pathway
0.0 2.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.2 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.8 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.5 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.7 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.5 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.4 PID SHP2 PATHWAY SHP2 signaling
0.0 0.6 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.3 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 1.0 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 25.5 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.1 2.0 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 1.5 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 0.8 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 1.1 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 1.3 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.7 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.9 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 1.9 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.9 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 1.1 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.7 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 2.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.9 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.9 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 2.3 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.4 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.3 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.6 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.4 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 0.6 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.4 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.3 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 1.5 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.5 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.2 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.1 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 5.2 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 0.2 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.5 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening