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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for SPIB

Z-value: 0.64

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Transcription factors associated with SPIB

Gene Symbol Gene ID Gene Info
SPIB
ENSG00000269404.2 Spi-B transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SPIBhg19_v2_chr19_+_50922187_50922215-0.252.3e-01Click!

Activity profile of SPIB motif

Sorted Z-values of SPIB motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_13213662 0.88 ENST00000264824.4
LYL1
lymphoblastic leukemia derived sequence 1
chr3_-_116163830 0.80 ENST00000333617.4
LSAMP
limbic system-associated membrane protein
chr17_-_29641084 0.78 ENST00000544462.1
EVI2B
ecotropic viral integration site 2B
chr6_+_136172820 0.74 ENST00000308191.6
PDE7B
phosphodiesterase 7B
chr19_+_50919056 0.74 ENST00000599632.1
CTD-2545M3.6
CTD-2545M3.6
chr1_+_120839412 0.72 ENST00000355228.4
FAM72B
family with sequence similarity 72, member B
chr17_-_72709050 0.71 ENST00000583937.1
ENST00000301573.9
ENST00000326165.6
ENST00000469092.1
CD300LF
CD300 molecule-like family member f
chr1_+_206138884 0.70 ENST00000341209.5
ENST00000607379.1
FAM72A
family with sequence similarity 72, member A
chr10_-_121302195 0.67 ENST00000369103.2
RGS10
regulator of G-protein signaling 10
chr8_+_125985531 0.55 ENST00000319286.5
ZNF572
zinc finger protein 572
chr5_-_66492562 0.55 ENST00000256447.4
CD180
CD180 molecule
chr13_+_108922228 0.53 ENST00000542136.1
TNFSF13B
tumor necrosis factor (ligand) superfamily, member 13b
chr13_+_31309645 0.50 ENST00000380490.3
ALOX5AP
arachidonate 5-lipoxygenase-activating protein
chr16_-_4850471 0.49 ENST00000592019.1
ENST00000586153.1
ROGDI
rogdi homolog (Drosophila)
chr2_+_96991935 0.49 ENST00000361124.4
ENST00000420728.1
ENST00000542887.1
ITPRIPL1
inositol 1,4,5-trisphosphate receptor interacting protein-like 1
chr11_-_64570706 0.47 ENST00000294066.2
ENST00000377350.3
MAP4K2
mitogen-activated protein kinase kinase kinase kinase 2
chr16_+_54964740 0.47 ENST00000394636.4
IRX5
iroquois homeobox 5
chr9_+_109625378 0.44 ENST00000277225.5
ENST00000457913.1
ENST00000472574.1
ZNF462
zinc finger protein 462
chr5_+_35856951 0.44 ENST00000303115.3
ENST00000343305.4
ENST00000506850.1
ENST00000511982.1
IL7R
interleukin 7 receptor
chr7_-_36764004 0.42 ENST00000431169.1
AOAH
acyloxyacyl hydrolase (neutrophil)
chr3_+_125694347 0.40 ENST00000505382.1
ENST00000511082.1
ROPN1B
rhophilin associated tail protein 1B
chr2_-_231084820 0.40 ENST00000258382.5
ENST00000338556.3
SP110
SP110 nuclear body protein
chr1_-_31230650 0.39 ENST00000294507.3
LAPTM5
lysosomal protein transmembrane 5
chr2_-_100759037 0.38 ENST00000317233.4
ENST00000423966.1
ENST00000416492.1
AFF3
AF4/FMR2 family, member 3
chr16_+_30960375 0.38 ENST00000318663.4
ENST00000566237.1
ENST00000562699.1
ORAI3
ORAI calcium release-activated calcium modulator 3
chr10_-_74856608 0.38 ENST00000307116.2
ENST00000373008.2
ENST00000412021.2
ENST00000394890.2
ENST00000263556.3
ENST00000440381.1
P4HA1
prolyl 4-hydroxylase, alpha polypeptide I
chr3_-_121379739 0.37 ENST00000428394.2
ENST00000314583.3
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr7_-_36764142 0.37 ENST00000258749.5
ENST00000535891.1
AOAH
acyloxyacyl hydrolase (neutrophil)
chr1_-_143913143 0.37 ENST00000400889.1
FAM72D
family with sequence similarity 72, member D
chr1_+_120839005 0.37 ENST00000369390.3
ENST00000452190.1
FAM72B
family with sequence similarity 72, member B
chr1_+_206138457 0.36 ENST00000367128.3
ENST00000431655.2
FAM72A
family with sequence similarity 72, member A
chr12_-_9885888 0.35 ENST00000327839.3
CLECL1
C-type lectin-like 1
chr20_+_62492566 0.35 ENST00000369916.3
ABHD16B
abhydrolase domain containing 16B
chr2_-_242089677 0.35 ENST00000405260.1
PASK
PAS domain containing serine/threonine kinase
chr19_-_17375527 0.35 ENST00000431146.2
ENST00000594190.1
USHBP1
Usher syndrome 1C binding protein 1
chr8_-_77912431 0.34 ENST00000357039.4
ENST00000522527.1
PEX2
peroxisomal biogenesis factor 2
chr9_-_130541017 0.33 ENST00000314830.8
SH2D3C
SH2 domain containing 3C
chr19_+_42381337 0.33 ENST00000597454.1
ENST00000444740.2
CD79A
CD79a molecule, immunoglobulin-associated alpha
chr12_+_50355647 0.33 ENST00000293599.6
AQP5
aquaporin 5
chr6_+_49431073 0.33 ENST00000335783.3
CENPQ
centromere protein Q
chr17_+_7461613 0.33 ENST00000438470.1
ENST00000436057.1
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr2_-_43019698 0.33 ENST00000431905.1
ENST00000294973.6
HAAO
3-hydroxyanthranilate 3,4-dioxygenase
chr6_-_139308777 0.33 ENST00000529597.1
ENST00000415951.2
ENST00000367663.4
ENST00000409812.2
REPS1
RALBP1 associated Eps domain containing 1
chr1_+_43855545 0.32 ENST00000372450.4
ENST00000310739.4
SZT2
seizure threshold 2 homolog (mouse)
chr5_-_64858944 0.32 ENST00000508421.1
ENST00000510693.1
ENST00000514814.1
ENST00000515497.1
ENST00000396679.1
CENPK
centromere protein K
chr10_+_49917751 0.32 ENST00000325239.5
ENST00000413659.2
WDFY4
WDFY family member 4
chr9_-_95640218 0.32 ENST00000395506.3
ENST00000375495.3
ENST00000332591.6
ZNF484
zinc finger protein 484
chr9_-_34397800 0.31 ENST00000297623.2
C9orf24
chromosome 9 open reading frame 24
chr10_-_79789291 0.31 ENST00000372371.3
POLR3A
polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
chr11_-_64851496 0.29 ENST00000404147.3
ENST00000275517.3
CDCA5
cell division cycle associated 5
chr19_-_48867171 0.29 ENST00000377431.2
ENST00000436660.2
ENST00000541566.1
TMEM143
transmembrane protein 143
chr16_+_30194916 0.29 ENST00000570045.1
ENST00000565497.1
ENST00000570244.1
CORO1A
coronin, actin binding protein, 1A
chr19_-_48867291 0.28 ENST00000435956.3
TMEM143
transmembrane protein 143
chr11_+_131240373 0.27 ENST00000374791.3
ENST00000436745.1
NTM
neurotrimin
chrX_+_109246285 0.27 ENST00000372073.1
ENST00000372068.2
ENST00000288381.4
TMEM164
transmembrane protein 164
chr11_+_60467047 0.27 ENST00000300226.2
MS4A8
membrane-spanning 4-domains, subfamily A, member 8
chr2_-_225266711 0.27 ENST00000389874.3
FAM124B
family with sequence similarity 124B
chr1_-_111506562 0.27 ENST00000485275.2
ENST00000369763.4
LRIF1
ligand dependent nuclear receptor interacting factor 1
chr1_-_120935894 0.27 ENST00000369383.4
ENST00000369384.4
FCGR1B
Fc fragment of IgG, high affinity Ib, receptor (CD64)
chr19_+_14551066 0.26 ENST00000342216.4
PKN1
protein kinase N1
chr15_-_33360342 0.26 ENST00000558197.1
FMN1
formin 1
chr2_-_225266743 0.26 ENST00000409685.3
FAM124B
family with sequence similarity 124B
chr8_-_125551278 0.26 ENST00000519232.1
ENST00000523888.1
ENST00000522810.1
ENST00000519548.1
ENST00000517678.1
ENST00000605953.1
ENST00000276692.6
TATDN1
TatD DNase domain containing 1
chr14_+_24616588 0.26 ENST00000324103.6
ENST00000559260.1
RNF31
ring finger protein 31
chr4_+_95129061 0.26 ENST00000354268.4
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr4_-_87281196 0.26 ENST00000359221.3
MAPK10
mitogen-activated protein kinase 10
chr2_-_190044480 0.26 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr4_-_87281224 0.25 ENST00000395169.3
ENST00000395161.2
MAPK10
mitogen-activated protein kinase 10
chr6_+_131148538 0.25 ENST00000541421.2
SMLR1
small leucine-rich protein 1
chr3_+_29322437 0.25 ENST00000434693.2
RBMS3
RNA binding motif, single stranded interacting protein 3
chr22_-_37640277 0.25 ENST00000401529.3
ENST00000249071.6
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr1_+_159272111 0.25 ENST00000368114.1
FCER1A
Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
chr19_+_35940486 0.25 ENST00000246549.2
FFAR2
free fatty acid receptor 2
chr5_-_58335281 0.25 ENST00000358923.6
PDE4D
phosphodiesterase 4D, cAMP-specific
chr2_-_231084617 0.25 ENST00000409815.2
SP110
SP110 nuclear body protein
chr9_+_120466650 0.25 ENST00000355622.6
TLR4
toll-like receptor 4
chr8_+_134203303 0.25 ENST00000519433.1
ENST00000517423.1
ENST00000377863.2
ENST00000220856.6
WISP1
WNT1 inducible signaling pathway protein 1
chr8_+_74903580 0.24 ENST00000284818.2
ENST00000518893.1
LY96
lymphocyte antigen 96
chr9_+_104296122 0.24 ENST00000389120.3
RNF20
ring finger protein 20, E3 ubiquitin protein ligase
chr7_+_106505696 0.24 ENST00000440650.2
ENST00000496166.1
ENST00000473541.1
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chrX_-_153637612 0.24 ENST00000369807.1
ENST00000369808.3
DNASE1L1
deoxyribonuclease I-like 1
chr3_+_16926441 0.24 ENST00000418129.2
ENST00000396755.2
PLCL2
phospholipase C-like 2
chr5_+_159848854 0.23 ENST00000517480.1
ENST00000520452.1
ENST00000393964.1
PTTG1
pituitary tumor-transforming 1
chr2_+_113885138 0.23 ENST00000409930.3
IL1RN
interleukin 1 receptor antagonist
chr1_-_145039949 0.23 ENST00000313382.9
PDE4DIP
phosphodiesterase 4D interacting protein
chr12_-_122240792 0.23 ENST00000545885.1
ENST00000542933.1
ENST00000428029.2
ENST00000541694.1
ENST00000536662.1
ENST00000535643.1
ENST00000541657.1
AC084018.1
RHOF
AC084018.1
ras homolog family member F (in filopodia)
chr14_-_98444438 0.23 ENST00000512901.2
C14orf64
chromosome 14 open reading frame 64
chr1_-_153919128 0.23 ENST00000361217.4
DENND4B
DENN/MADD domain containing 4B
chr16_-_50715196 0.23 ENST00000423026.2
SNX20
sorting nexin 20
chr19_+_2476116 0.23 ENST00000215631.4
ENST00000587345.1
GADD45B
growth arrest and DNA-damage-inducible, beta
chr10_-_62149433 0.22 ENST00000280772.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr2_+_202125219 0.22 ENST00000323492.7
CASP8
caspase 8, apoptosis-related cysteine peptidase
chr2_+_173940163 0.22 ENST00000539448.1
MLTK
Mitogen-activated protein kinase kinase kinase MLT
chr11_+_46722368 0.22 ENST00000311764.2
ZNF408
zinc finger protein 408
chr17_-_5138099 0.22 ENST00000571800.1
ENST00000574081.1
ENST00000399600.4
ENST00000574297.1
SCIMP
SLP adaptor and CSK interacting membrane protein
chrX_-_47489244 0.22 ENST00000469388.1
ENST00000396992.3
ENST00000377005.2
CFP
complement factor properdin
chr4_-_80994619 0.22 ENST00000404191.1
ANTXR2
anthrax toxin receptor 2
chr15_+_50716576 0.22 ENST00000560297.1
ENST00000307179.4
ENST00000396444.3
ENST00000433963.1
ENST00000425032.3
USP8
ubiquitin specific peptidase 8
chr11_+_64107663 0.22 ENST00000356786.5
CCDC88B
coiled-coil domain containing 88B
chr2_+_127413677 0.21 ENST00000356887.7
GYPC
glycophorin C (Gerbich blood group)
chr16_-_73082274 0.21 ENST00000268489.5
ZFHX3
zinc finger homeobox 3
chr11_-_47399942 0.21 ENST00000227163.4
SPI1
spleen focus forming virus (SFFV) proviral integration oncogene
chr2_+_68592305 0.21 ENST00000234313.7
PLEK
pleckstrin
chr11_-_47400078 0.21 ENST00000378538.3
SPI1
spleen focus forming virus (SFFV) proviral integration oncogene
chr10_-_52008313 0.21 ENST00000329428.6
ENST00000395526.4
ENST00000447815.1
ASAH2
N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
chr7_-_121944491 0.20 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1
FEZ family zinc finger 1
chr2_+_127413704 0.20 ENST00000409836.3
GYPC
glycophorin C (Gerbich blood group)
chr6_-_139309378 0.20 ENST00000450536.2
ENST00000258062.5
REPS1
RALBP1 associated Eps domain containing 1
chr1_+_209941827 0.20 ENST00000367023.1
TRAF3IP3
TRAF3 interacting protein 3
chr4_-_85887503 0.20 ENST00000509172.1
ENST00000322366.6
ENST00000295888.4
ENST00000502713.1
WDFY3
WD repeat and FYVE domain containing 3
chr8_-_101734170 0.20 ENST00000522387.1
ENST00000518196.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr5_+_169064245 0.20 ENST00000256935.8
DOCK2
dedicator of cytokinesis 2
chr3_+_46395219 0.19 ENST00000445132.2
ENST00000292301.4
CCR2
chemokine (C-C motif) receptor 2
chr19_-_17375541 0.19 ENST00000252597.3
USHBP1
Usher syndrome 1C binding protein 1
chr2_-_26101374 0.19 ENST00000435504.4
ASXL2
additional sex combs like 2 (Drosophila)
chr1_+_161475208 0.19 ENST00000367972.4
ENST00000271450.6
FCGR2A
Fc fragment of IgG, low affinity IIa, receptor (CD32)
chr6_+_36973406 0.19 ENST00000274963.8
FGD2
FYVE, RhoGEF and PH domain containing 2
chr13_-_111214015 0.19 ENST00000267328.3
RAB20
RAB20, member RAS oncogene family
chr7_+_106505912 0.19 ENST00000359195.3
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr11_+_47290914 0.19 ENST00000342922.4
MADD
MAP-kinase activating death domain
chr1_+_151584544 0.19 ENST00000458013.2
ENST00000368843.3
SNX27
sorting nexin family member 27
chr11_+_1860832 0.18 ENST00000252898.7
TNNI2
troponin I type 2 (skeletal, fast)
chr7_+_141811539 0.18 ENST00000550469.2
ENST00000477922.3
RP11-1220K2.2
Putative inactive maltase-glucoamylase-like protein LOC93432
chrX_+_24072833 0.18 ENST00000253039.4
EIF2S3
eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
chr15_+_42651691 0.18 ENST00000357568.3
ENST00000349748.3
ENST00000318023.7
ENST00000397163.3
CAPN3
calpain 3, (p94)
chr16_+_57576584 0.18 ENST00000340339.4
GPR114
G protein-coupled receptor 114
chr6_-_49430886 0.18 ENST00000274813.3
MUT
methylmalonyl CoA mutase
chr9_-_99145957 0.18 ENST00000375257.1
ENST00000253270.7
ENST00000375259.4
SLC35D2
solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
chr2_-_113993020 0.18 ENST00000465084.1
PAX8
paired box 8
chr8_-_101734308 0.18 ENST00000519004.1
ENST00000519363.1
ENST00000520142.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr22_-_37915535 0.18 ENST00000403299.1
CARD10
caspase recruitment domain family, member 10
chr19_+_49838653 0.18 ENST00000598095.1
ENST00000426897.2
ENST00000323906.4
ENST00000535669.2
ENST00000597602.1
ENST00000595660.1
CD37
CD37 molecule
chr1_-_20446020 0.18 ENST00000375105.3
PLA2G2D
phospholipase A2, group IID
chr2_-_152118352 0.18 ENST00000331426.5
RBM43
RNA binding motif protein 43
chr2_+_143886877 0.18 ENST00000295095.6
ARHGAP15
Rho GTPase activating protein 15
chr15_-_33360085 0.18 ENST00000334528.9
FMN1
formin 1
chr3_-_178984759 0.18 ENST00000349697.2
ENST00000497599.1
KCNMB3
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr1_+_167298281 0.18 ENST00000367862.5
POU2F1
POU class 2 homeobox 1
chr9_+_120466610 0.18 ENST00000394487.4
TLR4
toll-like receptor 4
chr13_+_53602894 0.18 ENST00000219022.2
OLFM4
olfactomedin 4
chr6_-_154677900 0.17 ENST00000265198.4
ENST00000520261.1
IPCEF1
interaction protein for cytohesin exchange factors 1
chr11_-_47400062 0.17 ENST00000533030.1
SPI1
spleen focus forming virus (SFFV) proviral integration oncogene
chr10_+_17851362 0.17 ENST00000331429.2
ENST00000457317.1
MRC1L1
cDNA FLJ56855, highly similar to Macrophage mannose receptor 1
chr14_+_85996471 0.17 ENST00000330753.4
FLRT2
fibronectin leucine rich transmembrane protein 2
chr7_-_14029515 0.17 ENST00000430479.1
ENST00000405218.2
ENST00000343495.5
ETV1
ets variant 1
chr5_+_40909354 0.17 ENST00000313164.9
C7
complement component 7
chr2_-_231084659 0.17 ENST00000258381.6
ENST00000358662.4
ENST00000455674.1
ENST00000392048.3
SP110
SP110 nuclear body protein
chr7_-_99756293 0.17 ENST00000316937.3
ENST00000456769.1
C7orf43
chromosome 7 open reading frame 43
chr7_+_86781847 0.17 ENST00000432366.2
ENST00000423590.2
ENST00000394703.5
DMTF1
cyclin D binding myb-like transcription factor 1
chr16_+_57392684 0.17 ENST00000219235.4
CCL22
chemokine (C-C motif) ligand 22
chr2_+_233925064 0.16 ENST00000359570.5
ENST00000538935.1
INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr10_+_11206925 0.16 ENST00000354440.2
ENST00000315874.4
ENST00000427450.1
CELF2
CUGBP, Elav-like family member 2
chr2_+_109237717 0.16 ENST00000409441.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr17_-_39093672 0.16 ENST00000209718.3
ENST00000436344.3
ENST00000485751.1
KRT23
keratin 23 (histone deacetylase inducible)
chr10_+_114133773 0.16 ENST00000354655.4
ACSL5
acyl-CoA synthetase long-chain family member 5
chr19_-_3786253 0.16 ENST00000585778.1
MATK
megakaryocyte-associated tyrosine kinase
chr11_+_1861399 0.16 ENST00000381905.3
TNNI2
troponin I type 2 (skeletal, fast)
chr22_-_37640456 0.16 ENST00000405484.1
ENST00000441619.1
ENST00000406508.1
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr8_+_121457642 0.16 ENST00000305949.1
MTBP
Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) binding protein, 104kDa
chrX_-_74376108 0.16 ENST00000339447.4
ENST00000373394.3
ENST00000529949.1
ENST00000534524.1
ENST00000253577.3
ABCB7
ATP-binding cassette, sub-family B (MDR/TAP), member 7
chr4_-_140005443 0.16 ENST00000510408.1
ENST00000420916.2
ENST00000358635.3
ELF2
E74-like factor 2 (ets domain transcription factor)
chr19_-_3786354 0.16 ENST00000395040.2
ENST00000310132.6
MATK
megakaryocyte-associated tyrosine kinase
chr7_-_150038704 0.16 ENST00000466675.1
ENST00000482669.1
ENST00000467793.1
ENST00000223271.3
RARRES2
retinoic acid receptor responder (tazarotene induced) 2
chr14_+_102228123 0.16 ENST00000422945.2
ENST00000554442.1
ENST00000556260.2
ENST00000328724.5
ENST00000557268.1
PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr22_-_40859415 0.15 ENST00000402630.1
ENST00000407029.1
MKL1
megakaryoblastic leukemia (translocation) 1
chr14_+_85996507 0.15 ENST00000554746.1
FLRT2
fibronectin leucine rich transmembrane protein 2
chr12_+_49717081 0.15 ENST00000547807.1
ENST00000551567.1
TROAP
trophinin associated protein
chr11_-_8680383 0.15 ENST00000299550.6
TRIM66
tripartite motif containing 66
chr16_-_30537839 0.15 ENST00000380412.5
ZNF768
zinc finger protein 768
chr7_+_86781677 0.15 ENST00000331242.7
ENST00000394702.3
ENST00000413276.2
ENST00000446796.2
ENST00000411766.2
ENST00000420131.1
ENST00000414630.2
ENST00000453049.1
ENST00000428819.1
ENST00000448598.1
ENST00000449088.3
ENST00000430405.3
DMTF1
cyclin D binding myb-like transcription factor 1
chr11_+_61100676 0.15 ENST00000394900.3
ENST00000532173.2
DAK
dihydroxyacetone kinase 2 homolog (S. cerevisiae)
chr20_+_2821340 0.15 ENST00000380445.3
ENST00000380469.3
VPS16
vacuolar protein sorting 16 homolog (S. cerevisiae)
chr2_+_85981008 0.15 ENST00000306279.3
ATOH8
atonal homolog 8 (Drosophila)
chr17_+_19030782 0.15 ENST00000344415.4
ENST00000577213.1
GRAPL
GRB2-related adaptor protein-like
chr14_+_45431379 0.15 ENST00000361577.3
ENST00000361462.2
ENST00000382233.2
FAM179B
family with sequence similarity 179, member B
chr3_-_52273098 0.15 ENST00000499914.2
ENST00000305533.5
ENST00000597542.1
TWF2
TLR9
twinfilin actin-binding protein 2
toll-like receptor 9
chr1_+_161632937 0.15 ENST00000236937.9
ENST00000367961.4
ENST00000358671.5
FCGR2B
Fc fragment of IgG, low affinity IIb, receptor (CD32)
chr20_-_20033052 0.15 ENST00000536226.1
CRNKL1
crooked neck pre-mRNA splicing factor 1
chr7_+_139528952 0.14 ENST00000416849.2
ENST00000436047.2
ENST00000414508.2
ENST00000448866.1
TBXAS1
thromboxane A synthase 1 (platelet)
chr2_+_242089833 0.14 ENST00000404405.3
ENST00000439916.1
ENST00000406106.3
ENST00000401987.1
PPP1R7
protein phosphatase 1, regulatory subunit 7
chr1_+_40840320 0.14 ENST00000372708.1
SMAP2
small ArfGAP2
chr15_+_91427642 0.14 ENST00000328850.3
ENST00000414248.2
FES
feline sarcoma oncogene
chr6_+_130339710 0.14 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr11_+_22696314 0.14 ENST00000532398.1
ENST00000433790.1
GAS2
growth arrest-specific 2
chr19_+_48828788 0.14 ENST00000594198.1
ENST00000597279.1
ENST00000593437.1
EMP3
epithelial membrane protein 3
chr1_+_104068312 0.14 ENST00000524631.1
ENST00000531883.1
ENST00000533099.1
ENST00000527062.1
RNPC3
RNA-binding region (RNP1, RRM) containing 3
chr14_+_74417192 0.14 ENST00000554320.1
COQ6
coenzyme Q6 monooxygenase
chr2_-_180871780 0.14 ENST00000410053.3
ENST00000295749.6
ENST00000404136.2
CWC22
CWC22 spliceosome-associated protein homolog (S. cerevisiae)
chr10_+_18429671 0.14 ENST00000282343.8
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr1_-_43855444 0.14 ENST00000372455.4
MED8
mediator complex subunit 8
chr1_+_46713404 0.14 ENST00000371975.4
ENST00000469835.1
RAD54L
RAD54-like (S. cerevisiae)
chr6_-_34524093 0.14 ENST00000544425.1
SPDEF
SAM pointed domain containing ETS transcription factor
chr19_-_42192096 0.14 ENST00000602225.1
CEACAM7
carcinoembryonic antigen-related cell adhesion molecule 7
chr1_+_46713357 0.14 ENST00000442598.1
RAD54L
RAD54-like (S. cerevisiae)
chr3_+_46283863 0.14 ENST00000545097.1
ENST00000541018.1
CCR3
chemokine (C-C motif) receptor 3
chrX_-_77582980 0.13 ENST00000373304.3
CYSLTR1
cysteinyl leukotriene receptor 1
chr12_-_15114191 0.13 ENST00000541380.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr1_-_145039835 0.13 ENST00000533259.1
PDE4DIP
phosphodiesterase 4D interacting protein
chr6_+_42952237 0.13 ENST00000485511.1
ENST00000394110.3
ENST00000472118.1
ENST00000461010.1
PPP2R5D
protein phosphatase 2, regulatory subunit B', delta
chr19_-_42192189 0.13 ENST00000401731.1
ENST00000338196.4
ENST00000006724.3
CEACAM7
carcinoembryonic antigen-related cell adhesion molecule 7

Network of associatons between targets according to the STRING database.

First level regulatory network of SPIB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0034125 negative regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034125) regulation of interleukin-4-mediated signaling pathway(GO:1902214)
0.2 0.2 GO:1902567 negative regulation of eosinophil activation(GO:1902567)
0.2 1.1 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.1 0.6 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.1 0.3 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.1 0.4 GO:0072092 ureteric bud invasion(GO:0072092)
0.1 0.5 GO:0001810 regulation of type I hypersensitivity(GO:0001810) type I hypersensitivity(GO:0016068)
0.1 0.3 GO:0034085 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.1 0.3 GO:0002277 myeloid dendritic cell activation involved in immune response(GO:0002277)
0.1 0.9 GO:0001955 blood vessel maturation(GO:0001955)
0.1 0.3 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.4 GO:0031296 positive regulation of germinal center formation(GO:0002636) B cell costimulation(GO:0031296)
0.1 0.5 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 0.4 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897) secretory granule localization(GO:0032252)
0.1 0.4 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.3 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.3 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 0.5 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.1 GO:0051795 positive regulation of catagen(GO:0051795)
0.1 0.7 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.1 0.2 GO:2000612 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.1 0.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.2 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.2 GO:0052148 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.1 0.5 GO:2001300 lipoxin metabolic process(GO:2001300)
0.1 0.2 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.1 0.3 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.1 0.4 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.2 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.3 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.0 0.2 GO:2001166 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0 0.7 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.3 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.3 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.4 GO:0070092 negative regulation of glycogen biosynthetic process(GO:0045719) regulation of glucagon secretion(GO:0070092)
0.0 0.3 GO:0023035 CD40 signaling pathway(GO:0023035)
0.0 0.4 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.3 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.4 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.8 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.1 GO:0031448 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.0 0.2 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555) fourth ventricle development(GO:0021592)
0.0 0.4 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.0 0.1 GO:1901895 positive regulation of interferon-alpha biosynthetic process(GO:0045356) negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.0 0.2 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.0 0.2 GO:0070560 protein secretion by platelet(GO:0070560)
0.0 0.2 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.1 GO:0002519 natural killer cell tolerance induction(GO:0002519) regulation of tolerance induction dependent upon immune response(GO:0002652) negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838) negative regulation of natural killer cell mediated immune response to tumor cell(GO:0002856) negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002859)
0.0 0.0 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.0 0.1 GO:0071484 response to high light intensity(GO:0009644) cellular response to light intensity(GO:0071484)
0.0 0.2 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.2 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.0 0.3 GO:0072672 neutrophil extravasation(GO:0072672)
0.0 0.2 GO:0061760 antifungal innate immune response(GO:0061760)
0.0 0.2 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.2 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.4 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.7 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.2 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.2 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.7 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.0 0.4 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.2 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 0.2 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.2 GO:0035973 aggrephagy(GO:0035973)
0.0 0.1 GO:0070253 somatostatin secretion(GO:0070253)
0.0 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.1 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.3 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.1 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.0 0.1 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.0 0.2 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.4 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.1 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.7 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.7 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:0038189 vestibulocochlear nerve structural organization(GO:0021649) neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) positive regulation of retinal ganglion cell axon guidance(GO:1902336) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.0 0.1 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.0 0.1 GO:0010585 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.2 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.3 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 0.2 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.1 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.0 GO:0061054 dermatome development(GO:0061054) regulation of dermatome development(GO:0061183)
0.0 0.0 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.2 GO:2000111 senescence-associated heterochromatin focus assembly(GO:0035986) positive regulation of macrophage apoptotic process(GO:2000111)
0.0 0.2 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.1 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.0 0.1 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.0 0.2 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0 0.2 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.2 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.1 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) regulation of barbed-end actin filament capping(GO:2000812)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.1 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.2 GO:0015886 heme transport(GO:0015886)
0.0 0.1 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 0.1 GO:0031642 negative regulation of myelination(GO:0031642)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.5 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.1 0.4 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 0.3 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.2 GO:0031673 H zone(GO:0031673)
0.1 0.3 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.2 GO:0032449 CBM complex(GO:0032449)
0.0 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.1 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.0 0.2 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.2 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.0 0.4 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306)
0.0 0.2 GO:0033503 HULC complex(GO:0033503)
0.0 0.1 GO:0071159 NF-kappaB complex(GO:0071159)
0.0 0.3 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.3 GO:0008278 cohesin complex(GO:0008278)
0.0 0.1 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.1 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.1 GO:0032010 phagolysosome(GO:0032010)
0.0 0.3 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.3 GO:0005861 troponin complex(GO:0005861)
0.0 0.2 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.1 GO:0045160 myosin I complex(GO:0045160)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.6 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.2 GO:0097342 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.2 0.7 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.2 0.5 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.1 0.4 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.1 0.8 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.1 0.5 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.2 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.1 0.5 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.2 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.1 0.2 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 0.7 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.4 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1 0.4 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.6 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.2 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 0.1 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.3 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.2 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.1 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.3 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.4 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.2 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.3 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.3 GO:0031014 troponin T binding(GO:0031014)
0.0 0.2 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 1.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.3 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.2 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.3 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.4 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0001032 RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.0 0.3 GO:0015250 water channel activity(GO:0015250)
0.0 0.2 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.2 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.3 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.3 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.1 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0016672 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.0 0.6 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.2 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.2 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.3 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0032357 oxidized purine DNA binding(GO:0032357)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.3 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.5 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.5 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.5 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.8 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.2 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.5 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.2 REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0 0.5 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.5 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.3 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.2 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.3 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.6 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.6 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.1 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.1 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 1.1 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.0 0.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling