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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for SPIC

Z-value: 0.78

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Transcription factors associated with SPIC

Gene Symbol Gene ID Gene Info
SPIC
ENSG00000166211.6 Spi-C transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SPIChg19_v2_chr12_+_101869096_101869199-0.067.8e-01Click!

Activity profile of SPIC motif

Sorted Z-values of SPIC motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_156587853 2.94 ENST00000506455.1
ENST00000511108.1
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr4_+_156588350 1.78 ENST00000296518.7
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr4_+_156588115 1.75 ENST00000455639.2
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr4_+_156588249 1.73 ENST00000393832.3
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr4_+_156587979 1.69 ENST00000511507.1
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr9_-_134145880 1.66 ENST00000372269.3
ENST00000464831.1
FAM78A
family with sequence similarity 78, member A
chr4_-_103682071 1.32 ENST00000505239.1
MANBA
mannosidase, beta A, lysosomal
chr10_+_35416090 1.23 ENST00000354759.3
CREM
cAMP responsive element modulator
chrX_+_55478538 1.22 ENST00000342972.1
MAGEH1
melanoma antigen family H, 1
chr7_+_150264365 1.17 ENST00000255945.2
ENST00000461940.1
GIMAP4
GTPase, IMAP family member 4
chr14_-_23285069 1.16 ENST00000554758.1
ENST00000397528.4
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr17_+_39382900 1.15 ENST00000377721.3
ENST00000455970.2
KRTAP9-2
keratin associated protein 9-2
chr14_-_23285011 1.11 ENST00000397532.3
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr19_+_32896646 1.06 ENST00000392250.2
DPY19L3
dpy-19-like 3 (C. elegans)
chr1_+_196788887 1.03 ENST00000320493.5
ENST00000367424.4
ENST00000367421.3
CFHR1
CFHR2
complement factor H-related 1
complement factor H-related 2
chr5_-_78281603 1.03 ENST00000264914.4
ARSB
arylsulfatase B
chr19_+_32896697 1.00 ENST00000586987.1
DPY19L3
dpy-19-like 3 (C. elegans)
chr12_+_15699286 0.95 ENST00000442921.2
ENST00000542557.1
ENST00000445537.2
ENST00000544244.1
PTPRO
protein tyrosine phosphatase, receptor type, O
chr7_-_15726296 0.93 ENST00000262041.5
MEOX2
mesenchyme homeobox 2
chr16_+_81812863 0.90 ENST00000359376.3
PLCG2
phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr9_-_77703115 0.83 ENST00000361092.4
ENST00000376808.4
NMRK1
nicotinamide riboside kinase 1
chr9_-_77703056 0.83 ENST00000376811.1
NMRK1
nicotinamide riboside kinase 1
chr10_+_112257596 0.78 ENST00000369583.3
DUSP5
dual specificity phosphatase 5
chr14_-_89883412 0.76 ENST00000557258.1
FOXN3
forkhead box N3
chr4_-_89152474 0.76 ENST00000515655.1
ABCG2
ATP-binding cassette, sub-family G (WHITE), member 2
chr4_-_103682145 0.75 ENST00000226578.4
MANBA
mannosidase, beta A, lysosomal
chr1_+_196912902 0.74 ENST00000476712.2
ENST00000367415.5
CFHR2
complement factor H-related 2
chr2_+_233925064 0.73 ENST00000359570.5
ENST00000538935.1
INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr22_-_37880543 0.72 ENST00000442496.1
MFNG
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr7_-_150329421 0.69 ENST00000493969.1
ENST00000328902.5
GIMAP6
GTPase, IMAP family member 6
chr1_+_150245177 0.68 ENST00000369098.3
C1orf54
chromosome 1 open reading frame 54
chr7_+_74188309 0.66 ENST00000289473.4
ENST00000433458.1
NCF1
neutrophil cytosolic factor 1
chr21_+_17566643 0.65 ENST00000419952.1
ENST00000445461.2
LINC00478
long intergenic non-protein coding RNA 478
chr11_+_68671310 0.65 ENST00000255078.3
ENST00000539224.1
IGHMBP2
immunoglobulin mu binding protein 2
chr12_+_51318513 0.62 ENST00000332160.4
METTL7A
methyltransferase like 7A
chr15_-_62457480 0.60 ENST00000380392.3
C2CD4B
C2 calcium-dependent domain containing 4B
chr5_-_93447333 0.58 ENST00000395965.3
ENST00000505869.1
ENST00000509163.1
FAM172A
family with sequence similarity 172, member A
chr7_+_95401851 0.58 ENST00000447467.2
DYNC1I1
dynein, cytoplasmic 1, intermediate chain 1
chr2_+_138721850 0.58 ENST00000329366.4
ENST00000280097.3
HNMT
histamine N-methyltransferase
chr10_+_18948311 0.58 ENST00000377275.3
ARL5B
ADP-ribosylation factor-like 5B
chr11_-_102401469 0.58 ENST00000260227.4
MMP7
matrix metallopeptidase 7 (matrilysin, uterine)
chr6_-_32191834 0.57 ENST00000375023.3
NOTCH4
notch 4
chr17_-_71088797 0.56 ENST00000580557.1
ENST00000579732.1
ENST00000578620.1
ENST00000542342.2
ENST00000255559.3
ENST00000579018.1
SLC39A11
solute carrier family 39, member 11
chr18_-_34408802 0.56 ENST00000590842.1
TPGS2
tubulin polyglutamylase complex subunit 2
chr12_-_95044309 0.55 ENST00000261226.4
TMCC3
transmembrane and coiled-coil domain family 3
chr16_+_30960375 0.54 ENST00000318663.4
ENST00000566237.1
ENST00000562699.1
ORAI3
ORAI calcium release-activated calcium modulator 3
chr12_+_1800179 0.54 ENST00000357103.4
ADIPOR2
adiponectin receptor 2
chr4_-_110723134 0.54 ENST00000510800.1
ENST00000512148.1
CFI
complement factor I
chr2_+_163175394 0.54 ENST00000446271.1
ENST00000429691.2
GCA
grancalcin, EF-hand calcium binding protein
chr4_-_99578789 0.53 ENST00000511651.1
ENST00000505184.1
TSPAN5
tetraspanin 5
chr4_-_99578776 0.53 ENST00000515287.1
TSPAN5
tetraspanin 5
chr5_-_78281775 0.52 ENST00000396151.3
ENST00000565165.1
ARSB
arylsulfatase B
chr18_-_53253323 0.52 ENST00000540999.1
ENST00000563888.2
TCF4
transcription factor 4
chr2_+_128848740 0.52 ENST00000375990.3
UGGT1
UDP-glucose glycoprotein glucosyltransferase 1
chr3_-_28390581 0.51 ENST00000479665.1
AZI2
5-azacytidine induced 2
chr3_+_184529948 0.51 ENST00000436792.2
ENST00000446204.2
ENST00000422105.1
VPS8
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr5_-_55412774 0.51 ENST00000434982.2
ANKRD55
ankyrin repeat domain 55
chr14_+_65878565 0.51 ENST00000556518.1
ENST00000557164.1
FUT8
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr2_+_61108771 0.51 ENST00000394479.3
REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chr19_+_38755042 0.50 ENST00000301244.7
SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr10_-_72141330 0.50 ENST00000395011.1
ENST00000395010.1
LRRC20
leucine rich repeat containing 20
chr18_-_53253112 0.50 ENST00000568673.1
ENST00000562847.1
ENST00000568147.1
TCF4
transcription factor 4
chr1_+_32538492 0.50 ENST00000336294.5
TMEM39B
transmembrane protein 39B
chr10_+_97471508 0.49 ENST00000453258.2
ENTPD1
ectonucleoside triphosphate diphosphohydrolase 1
chr3_+_184529929 0.49 ENST00000287546.4
ENST00000437079.3
VPS8
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr8_-_27941380 0.49 ENST00000413272.2
ENST00000341513.6
NUGGC
nuclear GTPase, germinal center associated
chr14_+_63671105 0.49 ENST00000316754.3
RHOJ
ras homolog family member J
chr12_+_12878829 0.49 ENST00000326765.6
APOLD1
apolipoprotein L domain containing 1
chr6_-_13328050 0.48 ENST00000420456.1
TBC1D7
TBC1 domain family, member 7
chr17_-_34313685 0.47 ENST00000435911.2
ENST00000586216.1
ENST00000394509.4
CCL14
chemokine (C-C motif) ligand 14
chr13_+_53602894 0.47 ENST00000219022.2
OLFM4
olfactomedin 4
chr5_-_10249990 0.47 ENST00000511437.1
ENST00000280330.8
ENST00000510047.1
FAM173B
family with sequence similarity 173, member B
chr10_+_94590910 0.46 ENST00000371547.4
EXOC6
exocyst complex component 6
chrX_+_151999511 0.45 ENST00000370274.3
ENST00000440023.1
ENST00000432467.1
NSDHL
NAD(P) dependent steroid dehydrogenase-like
chr3_+_51895621 0.45 ENST00000333127.3
IQCF2
IQ motif containing F2
chr6_+_116691001 0.45 ENST00000537543.1
DSE
dermatan sulfate epimerase
chr2_+_217524323 0.45 ENST00000456764.1
IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr12_-_6772303 0.44 ENST00000396807.4
ENST00000446105.2
ENST00000341550.4
ING4
inhibitor of growth family, member 4
chr4_-_159094194 0.44 ENST00000592057.1
ENST00000585682.1
ENST00000393807.5
FAM198B
family with sequence similarity 198, member B
chr7_-_21985489 0.43 ENST00000356195.5
ENST00000447180.1
ENST00000373934.4
ENST00000457951.1
CDCA7L
cell division cycle associated 7-like
chr20_-_33732952 0.43 ENST00000541621.1
EDEM2
ER degradation enhancer, mannosidase alpha-like 2
chr10_+_72238517 0.43 ENST00000263563.6
PALD1
phosphatase domain containing, paladin 1
chr1_-_24127256 0.43 ENST00000418277.1
GALE
UDP-galactose-4-epimerase
chr2_+_89998789 0.43 ENST00000453166.2
IGKV2D-28
immunoglobulin kappa variable 2D-28
chr14_+_91581011 0.43 ENST00000523894.1
ENST00000522322.1
ENST00000523771.1
C14orf159
chromosome 14 open reading frame 159
chr2_+_128848881 0.43 ENST00000259253.6
UGGT1
UDP-glucose glycoprotein glucosyltransferase 1
chr16_+_81528948 0.43 ENST00000539778.2
CMIP
c-Maf inducing protein
chr7_+_150382781 0.42 ENST00000223293.5
ENST00000474605.1
GIMAP2
GTPase, IMAP family member 2
chr20_+_48892848 0.41 ENST00000422459.1
RP11-290F20.3
RP11-290F20.3
chr12_+_7055631 0.41 ENST00000543115.1
ENST00000399448.1
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr2_+_33701286 0.41 ENST00000403687.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr11_+_47290914 0.41 ENST00000342922.4
MADD
MAP-kinase activating death domain
chr6_-_159466042 0.41 ENST00000338313.5
TAGAP
T-cell activation RhoGTPase activating protein
chr1_+_150245099 0.41 ENST00000369099.3
C1orf54
chromosome 1 open reading frame 54
chr11_+_60163918 0.41 ENST00000526375.1
ENST00000531783.1
ENST00000395001.1
MS4A14
membrane-spanning 4-domains, subfamily A, member 14
chr1_+_32538520 0.40 ENST00000438825.1
ENST00000456834.2
ENST00000373634.4
ENST00000427288.1
TMEM39B
transmembrane protein 39B
chr11_+_7618413 0.40 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr10_-_18948156 0.40 ENST00000414939.1
ENST00000449529.1
ENST00000456217.1
ENST00000444660.1
ARL5B-AS1
ARL5B antisense RNA 1
chr6_-_49430886 0.40 ENST00000274813.3
MUT
methylmalonyl CoA mutase
chr6_-_30585009 0.40 ENST00000376511.2
PPP1R10
protein phosphatase 1, regulatory subunit 10
chr17_-_5138099 0.40 ENST00000571800.1
ENST00000574081.1
ENST00000399600.4
ENST00000574297.1
SCIMP
SLP adaptor and CSK interacting membrane protein
chr11_+_7626950 0.40 ENST00000530181.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr10_+_102106829 0.39 ENST00000370355.2
SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chr17_-_7082861 0.39 ENST00000269299.3
ASGR1
asialoglycoprotein receptor 1
chr12_-_120907374 0.39 ENST00000550458.1
SRSF9
serine/arginine-rich splicing factor 9
chr19_+_45542295 0.38 ENST00000221455.3
ENST00000391953.4
ENST00000588936.1
CLASRP
CLK4-associating serine/arginine rich protein
chr3_-_151102529 0.38 ENST00000302632.3
P2RY12
purinergic receptor P2Y, G-protein coupled, 12
chr14_-_74416829 0.38 ENST00000534936.1
FAM161B
family with sequence similarity 161, member B
chrX_+_138612889 0.38 ENST00000218099.2
ENST00000394090.2
F9
coagulation factor IX
chr3_-_47324242 0.38 ENST00000456548.1
ENST00000432493.1
ENST00000335044.2
ENST00000444589.2
KIF9
kinesin family member 9
chr19_+_41903709 0.37 ENST00000542943.1
ENST00000457836.2
BCKDHA
branched chain keto acid dehydrogenase E1, alpha polypeptide
chr22_+_36649170 0.37 ENST00000438034.1
ENST00000427990.1
ENST00000347595.7
ENST00000397279.4
ENST00000433768.1
ENST00000440669.2
APOL1
apolipoprotein L, 1
chr14_+_75469606 0.37 ENST00000266126.5
EIF2B2
eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa
chr5_-_66492562 0.37 ENST00000256447.4
CD180
CD180 molecule
chr11_-_68671264 0.37 ENST00000362034.2
MRPL21
mitochondrial ribosomal protein L21
chr2_-_45795145 0.37 ENST00000535761.1
SRBD1
S1 RNA binding domain 1
chr17_-_76123101 0.37 ENST00000392467.3
TMC6
transmembrane channel-like 6
chr7_+_139025875 0.37 ENST00000297534.6
C7orf55
chromosome 7 open reading frame 55
chr2_+_138722028 0.37 ENST00000280096.5
HNMT
histamine N-methyltransferase
chr14_+_24702073 0.36 ENST00000399440.2
GMPR2
guanosine monophosphate reductase 2
chr2_+_120187465 0.36 ENST00000409826.1
ENST00000417645.1
TMEM37
transmembrane protein 37
chr1_+_174969262 0.36 ENST00000406752.1
ENST00000405362.1
CACYBP
calcyclin binding protein
chr3_-_47324008 0.36 ENST00000425853.1
KIF9
kinesin family member 9
chr19_+_10222189 0.36 ENST00000321826.4
P2RY11
purinergic receptor P2Y, G-protein coupled, 11
chr14_+_24702127 0.36 ENST00000557854.1
ENST00000348719.7
ENST00000559104.1
ENST00000456667.3
GMPR2
guanosine monophosphate reductase 2
chr14_+_24701819 0.36 ENST00000560139.1
ENST00000559910.1
GMPR2
guanosine monophosphate reductase 2
chrX_-_100604184 0.35 ENST00000372902.3
TIMM8A
translocase of inner mitochondrial membrane 8 homolog A (yeast)
chrX_-_45060135 0.35 ENST00000398000.2
ENST00000377934.4
CXorf36
chromosome X open reading frame 36
chr14_+_24701628 0.34 ENST00000355299.4
ENST00000559836.1
GMPR2
guanosine monophosphate reductase 2
chr11_+_6502675 0.34 ENST00000254616.6
ENST00000530751.1
TIMM10B
translocase of inner mitochondrial membrane 10 homolog B (yeast)
chr14_+_24702099 0.34 ENST00000420554.2
GMPR2
guanosine monophosphate reductase 2
chrX_+_47092314 0.34 ENST00000218348.3
USP11
ubiquitin specific peptidase 11
chr12_+_25205568 0.34 ENST00000548766.1
ENST00000556887.1
LRMP
lymphoid-restricted membrane protein
chr2_-_183291741 0.33 ENST00000351439.5
ENST00000409365.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr2_+_89999259 0.33 ENST00000558026.1
IGKV2D-28
immunoglobulin kappa variable 2D-28
chr1_+_155036204 0.33 ENST00000368409.3
ENST00000359751.4
ENST00000427683.2
ENST00000556931.1
ENST00000505139.1
EFNA4
EFNA3
EFNA3
ephrin-A4
ephrin-A3
Ephrin-A3; Uncharacterized protein; cDNA FLJ57652, highly similar to Ephrin-A3
chr6_-_8435706 0.33 ENST00000379660.4
SLC35B3
solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3
chr16_-_734318 0.33 ENST00000609261.1
ENST00000562111.1
ENST00000562824.1
ENST00000412368.2
ENST00000293882.4
ENST00000454700.1
JMJD8
jumonji domain containing 8
chr2_+_48667898 0.33 ENST00000281394.4
ENST00000294952.8
PPP1R21
protein phosphatase 1, regulatory subunit 21
chr1_-_36863481 0.33 ENST00000315732.2
LSM10
LSM10, U7 small nuclear RNA associated
chr5_+_36152163 0.33 ENST00000274255.6
SKP2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr11_+_133938820 0.33 ENST00000299106.4
ENST00000529443.2
JAM3
junctional adhesion molecule 3
chr3_+_52321827 0.32 ENST00000473032.1
ENST00000305690.8
ENST00000354773.4
ENST00000471180.1
ENST00000436784.2
GLYCTK
glycerate kinase
chr16_-_15736881 0.32 ENST00000540441.2
KIAA0430
KIAA0430
chr12_+_25205446 0.32 ENST00000557489.1
ENST00000354454.3
ENST00000536173.1
LRMP
lymphoid-restricted membrane protein
chr11_+_6226782 0.32 ENST00000316375.2
C11orf42
chromosome 11 open reading frame 42
chr5_+_36152091 0.32 ENST00000274254.5
SKP2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr16_+_28875126 0.32 ENST00000359285.5
ENST00000538342.1
SH2B1
SH2B adaptor protein 1
chrX_+_30233668 0.32 ENST00000378988.4
MAGEB2
melanoma antigen family B, 2
chr3_-_49142504 0.32 ENST00000306125.6
ENST00000420147.2
QARS
glutaminyl-tRNA synthetase
chr3_-_49142178 0.31 ENST00000452739.1
ENST00000414533.1
ENST00000417025.1
QARS
glutaminyl-tRNA synthetase
chr5_-_140013275 0.31 ENST00000512545.1
ENST00000302014.6
ENST00000401743.2
CD14
CD14 molecule
chr18_-_52989217 0.31 ENST00000570287.2
TCF4
transcription factor 4
chr2_-_99224915 0.31 ENST00000328709.3
ENST00000409997.1
COA5
cytochrome c oxidase assembly factor 5
chr11_-_68671244 0.31 ENST00000567045.1
ENST00000450904.2
MRPL21
mitochondrial ribosomal protein L21
chr1_-_22109484 0.31 ENST00000529637.1
USP48
ubiquitin specific peptidase 48
chr12_-_110486348 0.31 ENST00000547573.1
ENST00000546651.2
ENST00000551185.2
C12orf76
chromosome 12 open reading frame 76
chr4_-_111119804 0.31 ENST00000394607.3
ENST00000302274.3
ELOVL6
ELOVL fatty acid elongase 6
chr14_+_70233810 0.31 ENST00000394366.2
ENST00000553548.1
ENST00000553369.1
ENST00000557154.1
ENST00000451983.2
ENST00000553635.1
SRSF5
serine/arginine-rich splicing factor 5
chr1_-_145470383 0.31 ENST00000369314.1
ENST00000369313.3
POLR3GL
polymerase (RNA) III (DNA directed) polypeptide G (32kD)-like
chr6_+_32146131 0.31 ENST00000375094.3
RNF5
ring finger protein 5, E3 ubiquitin protein ligase
chr14_+_57735614 0.31 ENST00000261558.3
AP5M1
adaptor-related protein complex 5, mu 1 subunit
chr14_+_37667193 0.31 ENST00000539062.2
MIPOL1
mirror-image polydactyly 1
chr2_-_264024 0.31 ENST00000403712.2
ENST00000356150.5
ENST00000405430.1
SH3YL1
SH3 and SYLF domain containing 1
chr3_+_57094469 0.30 ENST00000334325.1
SPATA12
spermatogenesis associated 12
chr17_-_37934466 0.30 ENST00000583368.1
IKZF3
IKAROS family zinc finger 3 (Aiolos)
chr9_+_120466610 0.30 ENST00000394487.4
TLR4
toll-like receptor 4
chr9_-_130617029 0.30 ENST00000373203.4
ENG
endoglin
chr12_+_25205666 0.30 ENST00000547044.1
LRMP
lymphoid-restricted membrane protein
chr3_-_47324079 0.30 ENST00000352910.4
KIF9
kinesin family member 9
chr1_+_120839412 0.30 ENST00000355228.4
FAM72B
family with sequence similarity 72, member B
chr9_+_120466650 0.30 ENST00000355622.6
TLR4
toll-like receptor 4
chr14_+_88471468 0.30 ENST00000267549.3
GPR65
G protein-coupled receptor 65
chr3_+_124303472 0.30 ENST00000291478.5
KALRN
kalirin, RhoGEF kinase
chr19_-_18391708 0.30 ENST00000600972.1
JUND
jun D proto-oncogene
chr2_+_32390925 0.30 ENST00000440718.1
ENST00000379343.2
ENST00000282587.5
ENST00000435660.1
ENST00000538303.1
ENST00000357055.3
ENST00000406369.1
SLC30A6
solute carrier family 30 (zinc transporter), member 6
chr14_+_37667118 0.29 ENST00000556615.1
ENST00000327441.7
ENST00000536774.1
MIPOL1
mirror-image polydactyly 1
chr19_+_1026566 0.29 ENST00000348419.3
ENST00000565096.2
ENST00000562958.2
ENST00000562075.2
ENST00000607102.1
CNN2
calponin 2
chr21_+_34638656 0.29 ENST00000290200.2
IL10RB
interleukin 10 receptor, beta
chr1_+_22351977 0.29 ENST00000420503.1
ENST00000416769.1
ENST00000404210.2
LINC00339
long intergenic non-protein coding RNA 339
chr11_-_71791518 0.29 ENST00000537217.1
ENST00000366394.3
ENST00000358965.6
ENST00000546131.1
ENST00000543937.1
ENST00000368959.5
ENST00000541641.1
NUMA1
nuclear mitotic apparatus protein 1
chr19_+_45542773 0.29 ENST00000544944.2
CLASRP
CLK4-associating serine/arginine rich protein
chr17_+_67498538 0.29 ENST00000589647.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr3_+_148847371 0.28 ENST00000296051.2
ENST00000460120.1
HPS3
Hermansky-Pudlak syndrome 3
chr12_+_7055767 0.28 ENST00000447931.2
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr1_+_22963158 0.28 ENST00000438241.1
C1QA
complement component 1, q subcomponent, A chain
chr12_-_15114191 0.28 ENST00000541380.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr12_-_121019165 0.28 ENST00000341039.2
ENST00000357500.4
POP5
processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae)
chr1_+_222886694 0.28 ENST00000426638.1
ENST00000537020.1
ENST00000539697.1
BROX
BRO1 domain and CAAX motif containing
chr7_+_139026057 0.28 ENST00000541515.3
LUC7L2
LUC7-like 2 (S. cerevisiae)
chr16_-_28506840 0.28 ENST00000569430.1
CLN3
ceroid-lipofuscinosis, neuronal 3
chr1_-_242162375 0.28 ENST00000357246.3
MAP1LC3C
microtubule-associated protein 1 light chain 3 gamma
chr1_-_175161890 0.28 ENST00000545251.2
ENST00000423313.1
KIAA0040
KIAA0040
chr15_+_77287426 0.28 ENST00000558012.1
ENST00000267939.5
ENST00000379595.3
PSTPIP1
proline-serine-threonine phosphatase interacting protein 1
chr3_+_148583043 0.28 ENST00000296046.3
CPA3
carboxypeptidase A3 (mast cell)
chr4_-_47916613 0.27 ENST00000381538.3
ENST00000329043.3
NFXL1
nuclear transcription factor, X-box binding-like 1
chr4_-_47916543 0.27 ENST00000507489.1
NFXL1
nuclear transcription factor, X-box binding-like 1
chr19_+_13261216 0.27 ENST00000587885.1
ENST00000292433.3
IER2
immediate early response 2
chr1_+_46049706 0.27 ENST00000527470.1
ENST00000525515.1
ENST00000537798.1
ENST00000402363.3
ENST00000528238.1
ENST00000350030.3
ENST00000470768.1
ENST00000372052.4
ENST00000351223.3
NASP
nuclear autoantigenic sperm protein (histone-binding)
chr1_-_154928562 0.27 ENST00000368463.3
ENST00000539880.1
ENST00000542459.1
ENST00000368460.3
ENST00000368465.1
PBXIP1
pre-B-cell leukemia homeobox interacting protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of SPIC

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 9.9 GO:0052551 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.5 1.4 GO:0061582 intestinal epithelial cell migration(GO:0061582)
0.4 2.5 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.3 1.0 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.3 0.9 GO:0097359 UDP-glucosylation(GO:0097359)
0.3 1.1 GO:0002316 follicular B cell differentiation(GO:0002316)
0.3 0.8 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.3 2.1 GO:0018406 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.2 0.7 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.2 0.6 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.2 1.0 GO:0044565 dendritic cell proliferation(GO:0044565)
0.2 0.6 GO:0070428 negative regulation of interleukin-23 production(GO:0032707) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.2 0.5 GO:0001300 chronological cell aging(GO:0001300)
0.2 0.5 GO:0036071 N-glycan fucosylation(GO:0036071)
0.2 2.4 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.2 0.9 GO:0001692 histamine metabolic process(GO:0001692)
0.2 0.9 GO:0001757 somite specification(GO:0001757)
0.1 0.7 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.1 0.1 GO:1903378 positive regulation of oxidative stress-induced neuron death(GO:1903223) positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.1 0.4 GO:0036511 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.1 0.9 GO:0071461 cellular response to redox state(GO:0071461)
0.1 0.4 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1 0.4 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.1 2.1 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.1 0.4 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.1 0.5 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 0.6 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.3 GO:0071988 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.1 0.3 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 0.1 GO:0036510 trimming of terminal mannose on C branch(GO:0036510)
0.1 1.1 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.2 GO:0061569 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.1 0.3 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1 0.2 GO:1902995 regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995)
0.1 0.3 GO:0071725 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.1 0.9 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 0.2 GO:0034059 response to anoxia(GO:0034059)
0.1 0.3 GO:0039507 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.1 0.2 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 0.3 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.1 0.2 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 0.5 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.1 0.3 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.1 0.4 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.1 0.6 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
0.1 0.4 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.1 0.4 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.1 0.3 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.1 0.3 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.1 0.8 GO:0042908 xenobiotic transport(GO:0042908)
0.1 1.8 GO:0043101 purine-containing compound salvage(GO:0043101)
0.1 0.6 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.1 0.2 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.1 0.2 GO:0019413 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542)
0.1 0.8 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.5 GO:0061042 adiponectin-activated signaling pathway(GO:0033211) vascular wound healing(GO:0061042)
0.1 0.2 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.1 0.1 GO:2001186 negative regulation of CD8-positive, alpha-beta T cell activation(GO:2001186)
0.1 0.2 GO:0006404 RNA import into nucleus(GO:0006404)
0.1 0.3 GO:0007525 somatic muscle development(GO:0007525)
0.1 0.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.1 0.2 GO:0019085 early viral transcription(GO:0019085)
0.1 0.2 GO:0018874 benzoate metabolic process(GO:0018874)
0.1 0.3 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211) regulation of ovarian follicle development(GO:2000354)
0.0 0.8 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.0 0.2 GO:0036369 transcription factor catabolic process(GO:0036369)
0.0 0.4 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.8 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.1 GO:0061188 negative regulation of chromatin silencing at rDNA(GO:0061188)
0.0 0.2 GO:0036269 swimming behavior(GO:0036269)
0.0 0.1 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0 0.3 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 1.7 GO:0009435 NAD biosynthetic process(GO:0009435)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.3 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.0 0.2 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.1 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.3 GO:0034036 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.0 0.2 GO:1905244 regulation of modification of synaptic structure(GO:1905244)
0.0 1.0 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.2 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.2 GO:0006447 regulation of translational initiation by iron(GO:0006447)
0.0 0.5 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.3 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.0 0.3 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.2 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0 0.1 GO:0042214 terpene metabolic process(GO:0042214)
0.0 0.5 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.5 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.3 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.2 GO:1903756 positive regulation of dendritic spine maintenance(GO:1902952) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.0 0.3 GO:0006477 protein sulfation(GO:0006477)
0.0 1.1 GO:0071801 regulation of podosome assembly(GO:0071801)
0.0 0.2 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 0.1 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.0 0.5 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.3 GO:0040034 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0 0.3 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.2 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.0 0.1 GO:1903093 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.0 0.2 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.5 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.2 GO:0033087 negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0 0.1 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
0.0 0.3 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.5 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.5 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:0045416 positive regulation of interleukin-8 biosynthetic process(GO:0045416)
0.0 0.2 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.0 0.6 GO:0044849 estrous cycle(GO:0044849)
0.0 0.1 GO:0045006 DNA deamination(GO:0045006) DNA cytosine deamination(GO:0070383)
0.0 0.5 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.0 0.2 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.1 GO:2000397 regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.0 0.2 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.2 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.1 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 1.1 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.1 GO:1900229 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.0 0.4 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 1.2 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.1 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.0 0.4 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 1.0 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.2 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.5 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.1 GO:0034085 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.1 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0 0.1 GO:1901873 regulation of post-translational protein modification(GO:1901873)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.2 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.1 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.0 0.2 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.2 GO:1902961 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.0 0.1 GO:0070346 positive regulation of fat cell proliferation(GO:0070346)
0.0 0.0 GO:0072716 response to actinomycin D(GO:0072716) cellular response to actinomycin D(GO:0072717)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.2 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.2 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.2 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.1 GO:0008228 opsonization(GO:0008228)
0.0 0.1 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.1 GO:0042078 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.1 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.0 0.3 GO:0002003 angiotensin maturation(GO:0002003)
0.0 2.2 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.3 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.3 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.0 GO:0015785 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.0 0.1 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.4 GO:0010226 response to lithium ion(GO:0010226)
0.0 0.0 GO:0051795 positive regulation of catagen(GO:0051795) activation of meiosis(GO:0090427)
0.0 0.2 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.0 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0 0.1 GO:0070980 biphenyl catabolic process(GO:0070980)
0.0 0.2 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.1 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.0 0.6 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.0 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.0 0.2 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.5 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.1 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.2 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 0.0 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.0 0.1 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 0.3 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.0 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686)
0.0 0.0 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.3 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.4 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.1 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.2 GO:0021860 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0 0.1 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.5 GO:0006506 GPI anchor metabolic process(GO:0006505) GPI anchor biosynthetic process(GO:0006506)
0.0 0.2 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 9.9 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.3 1.8 GO:1902560 GMP reductase complex(GO:1902560)
0.2 0.9 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.2 0.5 GO:0072563 endothelial microparticle(GO:0072563)
0.2 1.0 GO:0033263 CORVET complex(GO:0033263)
0.1 0.4 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.1 0.7 GO:0005602 complement component C1 complex(GO:0005602)
0.1 0.1 GO:0019034 viral replication complex(GO:0019034)
0.1 0.3 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.1 0.3 GO:0055028 cortical microtubule(GO:0055028)
0.1 0.3 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 0.8 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.4 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 0.7 GO:0032797 SMN complex(GO:0032797)
0.1 0.4 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.4 GO:0032010 phagolysosome(GO:0032010)
0.0 0.2 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.6 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 1.8 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.3 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.4 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.3 GO:0035976 AP1 complex(GO:0035976)
0.0 0.4 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.2 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 3.1 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.1 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.0 0.3 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.6 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.2 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 1.0 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.1 GO:0031673 H zone(GO:0031673)
0.0 0.3 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.2 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.2 GO:0033503 HULC complex(GO:0033503)
0.0 0.3 GO:0034464 BBSome(GO:0034464)
0.0 2.2 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.5 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.3 GO:0033010 paranodal junction(GO:0033010)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 2.6 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.1 GO:1990357 terminal web(GO:1990357)
0.0 0.2 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.6 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 1.4 GO:0005871 kinesin complex(GO:0005871)
0.0 0.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.6 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 1.2 GO:0045095 keratin filament(GO:0045095)
0.0 0.2 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.9 GO:0031228 intrinsic component of Golgi membrane(GO:0031228)
0.0 0.2 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.1 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 1.1 GO:0005811 lipid particle(GO:0005811)
0.0 0.3 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.2 GO:0097342 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0 0.1 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.0 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.0 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.4 1.7 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.4 9.9 GO:0004383 guanylate cyclase activity(GO:0004383)
0.3 0.9 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.3 1.8 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.2 0.6 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.2 0.7 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.2 0.5 GO:0046921 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.2 2.3 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 0.6 GO:0030107 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
0.1 2.5 GO:0015923 mannosidase activity(GO:0015923)
0.1 0.4 GO:0003826 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.1 0.7 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1 1.6 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.5 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 0.3 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.9 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.1 0.4 GO:0047820 D-glutamate cyclase activity(GO:0047820)
0.1 0.8 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 0.3 GO:0071209 U7 snRNA binding(GO:0071209)
0.1 0.2 GO:0090554 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 0.4 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1 0.2 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.1 0.9 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.2 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.1 2.1 GO:0000030 mannosyltransferase activity(GO:0000030)
0.1 1.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.4 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.3 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.1 0.2 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.1 0.6 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.3 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.1 0.5 GO:0005534 galactose binding(GO:0005534)
0.1 1.8 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 0.3 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.1 0.3 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.1 0.2 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.1 0.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.2 GO:0019770 IgG receptor activity(GO:0019770)
0.1 0.2 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 0.4 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.2 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.3 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.2 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.2 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.0 0.3 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.3 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.8 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.5 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.2 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.8 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.2 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.1 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.8 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.5 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.4 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.2 GO:0032089 NACHT domain binding(GO:0032089)
0.0 0.2 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.3 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.3 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 1.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.1 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.0 0.3 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 0.5 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.3 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.1 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.0 0.1 GO:1904492 Ac-Asp-Glu binding(GO:1904492) tetrahydrofolyl-poly(glutamate) polymer binding(GO:1904493)
0.0 0.1 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.0 0.1 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.5 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.1 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.0 0.5 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.2 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 1.4 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.5 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.2 GO:0043426 MRF binding(GO:0043426)
0.0 0.2 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0000035 acyl binding(GO:0000035)
0.0 0.1 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.1 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.0 0.3 GO:0034452 dynactin binding(GO:0034452)
0.0 0.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.2 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 0.3 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.2 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.3 GO:0000295 adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.0 0.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.3 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.1 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.2 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.1 GO:0052857 NADHX epimerase activity(GO:0052856) NADPHX epimerase activity(GO:0052857)
0.0 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.0 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.0 GO:0004947 bradykinin receptor activity(GO:0004947)
0.0 0.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.3 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.2 GO:0031386 protein tag(GO:0031386)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 0.5 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.2 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 1.4 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.4 GO:0005123 death receptor binding(GO:0005123)
0.0 0.0 GO:0004040 amidase activity(GO:0004040)
0.0 0.1 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.0 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.1 GO:0015266 protein channel activity(GO:0015266)
0.0 0.0 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.2 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.1 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.1 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0 0.5 GO:0005484 SNAP receptor activity(GO:0005484)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.4 PID EPO PATHWAY EPO signaling pathway
0.0 0.2 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.7 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.1 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.6 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.0 PID MYC PATHWAY C-MYC pathway
0.0 0.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.5 PID ALK1 PATHWAY ALK1 signaling events
0.0 2.1 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.2 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.5 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.7 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.7 PID INSULIN PATHWAY Insulin Pathway
0.0 0.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.4 PID RAS PATHWAY Regulation of Ras family activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 10.1 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.1 1.5 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 1.5 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 0.9 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 1.8 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 0.8 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 0.8 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 1.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.1 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 2.1 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.1 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.9 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 1.3 REACTOME KINESINS Genes involved in Kinesins
0.0 1.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.4 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.3 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.6 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.2 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.6 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.5 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.3 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.2 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 0.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.3 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.1 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.4 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.1 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.2 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.1 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.2 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling