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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for SREBF1_TFE3

Z-value: 1.07

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Transcription factors associated with SREBF1_TFE3

Gene Symbol Gene ID Gene Info
ENSG00000072310.12 sterol regulatory element binding transcription factor 1
ENSG00000068323.12 transcription factor binding to IGHM enhancer 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TFE3hg19_v2_chrX_-_48901012_48901050-0.301.4e-01Click!
SREBF1hg19_v2_chr17_-_17740287_177403160.301.5e-01Click!

Activity profile of SREBF1_TFE3 motif

Sorted Z-values of SREBF1_TFE3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_39382900 5.83 ENST00000377721.3
ENST00000455970.2
keratin associated protein 9-2
chr1_+_221051699 4.96 ENST00000366903.6
H2.0-like homeobox
chr8_-_81083890 3.07 ENST00000518937.1
tumor protein D52
chr17_+_78075498 2.92 ENST00000302262.3
glucosidase, alpha; acid
chr19_-_15236173 2.75 ENST00000527093.1
ilvB (bacterial acetolactate synthase)-like
chr4_-_101439242 2.62 ENST00000296420.4
endomucin
chr17_+_78075361 2.55 ENST00000577106.1
ENST00000390015.3
glucosidase, alpha; acid
chr12_+_93964746 2.49 ENST00000536696.2
suppressor of cytokine signaling 2
chr14_-_54420133 2.48 ENST00000559501.1
ENST00000558984.1
bone morphogenetic protein 4
chr4_-_16900410 2.42 ENST00000304523.5
LIM domain binding 2
chr4_-_16900184 2.42 ENST00000515064.1
LIM domain binding 2
chr4_-_16900217 2.40 ENST00000441778.2
LIM domain binding 2
chr4_-_16900242 2.39 ENST00000502640.1
ENST00000506732.1
LIM domain binding 2
chr1_+_84630053 2.38 ENST00000394838.2
ENST00000370682.3
ENST00000432111.1
protein kinase, cAMP-dependent, catalytic, beta
chr17_+_39394250 2.36 ENST00000254072.6
keratin associated protein 9-8
chr6_+_160390102 2.31 ENST00000356956.1
insulin-like growth factor 2 receptor
chr1_+_84630645 2.26 ENST00000394839.2
protein kinase, cAMP-dependent, catalytic, beta
chr8_-_81083731 2.25 ENST00000379096.5
tumor protein D52
chr17_-_46688334 2.22 ENST00000239165.7
homeobox B7
chr14_-_54955721 2.14 ENST00000554908.1
glia maturation factor, beta
chr5_-_172198190 2.12 ENST00000239223.3
dual specificity phosphatase 1
chr9_-_79307096 2.10 ENST00000376717.2
ENST00000223609.6
ENST00000443509.2
prune homolog 2 (Drosophila)
chr22_-_36903101 2.08 ENST00000397224.4
FAD-dependent oxidoreductase domain containing 2
chr9_+_40028620 1.93 ENST00000426179.1
AL353791.1
chr11_+_59522837 1.92 ENST00000437946.2
syntaxin 3
chr19_+_39903185 1.89 ENST00000409794.3
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr14_+_61789382 1.89 ENST00000555082.1
protein kinase C, eta
chr17_-_66951474 1.88 ENST00000269080.2
ATP-binding cassette, sub-family A (ABC1), member 8
chr21_-_35987438 1.86 ENST00000313806.4
regulator of calcineurin 1
chr16_-_28503327 1.86 ENST00000535392.1
ENST00000395653.4
ceroid-lipofuscinosis, neuronal 3
chr16_-_28503357 1.83 ENST00000333496.9
ENST00000561505.1
ENST00000567963.1
ENST00000354630.5
ENST00000355477.5
ENST00000357076.5
ENST00000565688.1
ENST00000359984.7
ceroid-lipofuscinosis, neuronal 3
chrX_+_77166172 1.79 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATPase, Cu++ transporting, alpha polypeptide
chrX_+_55744228 1.78 ENST00000262850.7
Ras-related GTP binding B
chr8_-_17941575 1.77 ENST00000417108.2
N-acylsphingosine amidohydrolase (acid ceramidase) 1
chr11_+_67159416 1.77 ENST00000307980.2
ENST00000544620.1
RAD9 homolog A (S. pombe)
chr7_+_106685079 1.74 ENST00000265717.4
protein kinase, cAMP-dependent, regulatory, type II, beta
chr10_+_99344104 1.74 ENST00000555577.1
ENST00000370649.3
phosphatidylinositol 4-kinase type 2 alpha
Phosphatidylinositol 4-kinase type 2-alpha; Uncharacterized protein
chr17_-_58469591 1.74 ENST00000589335.1
ubiquitin specific peptidase 32
chr1_-_154928562 1.73 ENST00000368463.3
ENST00000539880.1
ENST00000542459.1
ENST00000368460.3
ENST00000368465.1
pre-B-cell leukemia homeobox interacting protein 1
chr16_-_57219721 1.73 ENST00000562406.1
ENST00000568671.1
ENST00000567044.1
family with sequence similarity 192, member A
chrX_+_101975643 1.73 ENST00000361229.4
basic helix-loop-helix domain containing, class B, 9
chrX_+_101975619 1.73 ENST00000457056.1
basic helix-loop-helix domain containing, class B, 9
chr6_-_84418860 1.71 ENST00000521743.1
synaptosomal-associated protein, 91kDa
chr2_-_238499303 1.70 ENST00000409576.1
RAB17, member RAS oncogene family
chr3_-_122512619 1.69 ENST00000383659.1
ENST00000306103.2
HSPB (heat shock 27kDa) associated protein 1
chr12_+_93964158 1.68 ENST00000549206.1
suppressor of cytokine signaling 2
chr17_-_76124711 1.66 ENST00000306591.7
ENST00000590602.1
transmembrane channel-like 6
chrX_+_53123314 1.65 ENST00000605526.1
ENST00000604062.1
ENST00000604369.1
ENST00000366185.2
ENST00000604849.1
long intergenic non-protein coding RNA 1155
chr16_-_28503080 1.65 ENST00000565316.1
ENST00000565778.1
ENST00000357857.9
ENST00000568558.1
ENST00000357806.7
ceroid-lipofuscinosis, neuronal 3
chr19_+_5681011 1.64 ENST00000581893.1
ENST00000411793.2
ENST00000301382.4
ENST00000581773.1
ENST00000423665.2
ENST00000583928.1
ENST00000342970.2
ENST00000422535.2
ENST00000581521.1
ENST00000339423.2
hydroxysteroid (11-beta) dehydrogenase 1-like
chr6_-_84418841 1.63 ENST00000369694.2
ENST00000195649.6
synaptosomal-associated protein, 91kDa
chr4_-_186733363 1.62 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
sorbin and SH3 domain containing 2
chr17_-_76124812 1.61 ENST00000592063.1
ENST00000589271.1
ENST00000322933.4
ENST00000589553.1
transmembrane channel-like 6
chr13_+_39612485 1.61 ENST00000379599.2
NHL repeat containing 3
chr2_+_148778570 1.59 ENST00000407073.1
methyl-CpG binding domain protein 5
chrX_+_55744166 1.58 ENST00000374941.4
ENST00000414239.1
Ras-related GTP binding B
chr16_-_2097787 1.58 ENST00000566380.1
ENST00000219066.1
nth endonuclease III-like 1 (E. coli)
chr11_+_59522900 1.57 ENST00000529177.1
syntaxin 3
chr11_-_116968987 1.56 ENST00000434315.2
ENST00000292055.4
ENST00000375288.1
ENST00000542607.1
ENST00000445177.1
ENST00000375300.1
ENST00000446921.2
SIK family kinase 3
chr16_-_4588469 1.52 ENST00000588381.1
ENST00000563332.2
cell death-inducing p53 target 1
chr16_-_67185117 1.52 ENST00000449549.3
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
chr11_+_7534999 1.48 ENST00000528947.1
ENST00000299492.4
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr9_+_117350009 1.46 ENST00000374050.3
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1
chrX_+_102883887 1.44 ENST00000372625.3
ENST00000372624.3
transcription elongation factor A (SII)-like 1
chr6_-_84419101 1.41 ENST00000520302.1
ENST00000520213.1
ENST00000439399.2
ENST00000428679.2
ENST00000437520.1
synaptosomal-associated protein, 91kDa
chr6_+_138188551 1.40 ENST00000237289.4
ENST00000433680.1
tumor necrosis factor, alpha-induced protein 3
chrX_+_118108601 1.40 ENST00000371628.3
LON peptidase N-terminal domain and ring finger 3
chr17_-_73975444 1.37 ENST00000293217.5
ENST00000537812.1
acyl-CoA oxidase 1, palmitoyl
chrX_+_118108571 1.35 ENST00000304778.7
LON peptidase N-terminal domain and ring finger 3
chr15_-_72668805 1.34 ENST00000268097.5
hexosaminidase A (alpha polypeptide)
chr8_+_21915368 1.33 ENST00000265800.5
ENST00000517418.1
dematin actin binding protein
chrX_-_34675391 1.32 ENST00000275954.3
transmembrane protein 47
chr3_+_184529929 1.32 ENST00000287546.4
ENST00000437079.3
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr1_-_113498616 1.31 ENST00000433570.4
ENST00000538576.1
ENST00000458229.1
solute carrier family 16 (monocarboxylate transporter), member 1
chr12_+_51632666 1.31 ENST00000604900.1
DAZ associated protein 2
chr3_+_184529948 1.28 ENST00000436792.2
ENST00000446204.2
ENST00000422105.1
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr16_-_4588822 1.27 ENST00000564828.1
cell death-inducing p53 target 1
chr7_+_156902674 1.27 ENST00000594086.1
Protein LOC100996426
chr3_+_37903432 1.27 ENST00000443503.2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr8_-_54755459 1.26 ENST00000524234.1
ENST00000521275.1
ENST00000396774.2
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr1_-_156265438 1.26 ENST00000362007.1
chromosome 1 open reading frame 85
chr13_+_39612442 1.24 ENST00000470258.1
ENST00000379600.3
NHL repeat containing 3
chr1_-_95007193 1.24 ENST00000370207.4
ENST00000334047.7
coagulation factor III (thromboplastin, tissue factor)
chr22_-_39636914 1.22 ENST00000381551.4
platelet-derived growth factor beta polypeptide
chr16_-_4588762 1.22 ENST00000562334.1
ENST00000562579.1
ENST00000567695.1
ENST00000563507.1
cell death-inducing p53 target 1
chr5_+_78532003 1.22 ENST00000396137.4
junction mediating and regulatory protein, p53 cofactor
chr12_+_12878829 1.21 ENST00000326765.6
apolipoprotein L domain containing 1
chr8_-_54755789 1.20 ENST00000359530.2
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr2_-_197036289 1.20 ENST00000263955.4
serine/threonine kinase 17b
chr6_-_80657292 1.19 ENST00000369816.4
ELOVL fatty acid elongase 4
chr1_+_32042105 1.19 ENST00000457433.2
ENST00000441210.2
tubulointerstitial nephritis antigen-like 1
chr22_-_37882395 1.18 ENST00000416983.3
ENST00000424765.2
ENST00000356998.3
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr2_-_160143158 1.18 ENST00000409124.1
ENST00000358147.4
WD repeat, sterile alpha motif and U-box domain containing 1
chrX_-_102565858 1.18 ENST00000449185.1
ENST00000536889.1
brain expressed X-linked 2
chr2_-_85829780 1.18 ENST00000334462.5
transmembrane protein 150A
chr17_-_18266765 1.17 ENST00000354098.3
serine hydroxymethyltransferase 1 (soluble)
chr2_-_160143084 1.17 ENST00000409990.3
WD repeat, sterile alpha motif and U-box domain containing 1
chr2_-_85829811 1.17 ENST00000306353.3
transmembrane protein 150A
chr2_-_160143242 1.17 ENST00000359774.4
WD repeat, sterile alpha motif and U-box domain containing 1
chr14_-_74551096 1.15 ENST00000350259.4
aldehyde dehydrogenase 6 family, member A1
chr2_-_160143059 1.14 ENST00000392796.3
WD repeat, sterile alpha motif and U-box domain containing 1
chr8_+_74903580 1.14 ENST00000284818.2
ENST00000518893.1
lymphocyte antigen 96
chr11_-_67888671 1.13 ENST00000265689.4
choline kinase alpha
chr14_-_88459182 1.13 ENST00000544807.2
galactosylceramidase
chr17_+_65821636 1.11 ENST00000544778.2
bromodomain PHD finger transcription factor
chr22_+_19467261 1.10 ENST00000455750.1
ENST00000437685.2
ENST00000263201.1
ENST00000404724.3
cell division cycle 45
chr7_-_100808843 1.10 ENST00000249330.2
VGF nerve growth factor inducible
chr7_-_100808394 1.10 ENST00000445482.2
VGF nerve growth factor inducible
chr1_+_32042131 1.10 ENST00000271064.7
ENST00000537531.1
tubulointerstitial nephritis antigen-like 1
chr13_-_52585547 1.09 ENST00000448424.2
ENST00000400370.3
ENST00000418097.2
ENST00000242839.4
ENST00000400366.3
ENST00000344297.5
ATPase, Cu++ transporting, beta polypeptide
chr9_-_13175823 1.09 ENST00000545857.1
multiple PDZ domain protein
chr6_-_44225231 1.09 ENST00000538577.1
ENST00000537814.1
ENST00000393810.1
ENST00000393812.3
solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2
chr6_+_42018614 1.08 ENST00000465926.1
ENST00000482432.1
TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
chr16_+_8806800 1.07 ENST00000561870.1
ENST00000396600.2
4-aminobutyrate aminotransferase
chr9_-_123476719 1.07 ENST00000373930.3
multiple EGF-like-domains 9
chr3_-_4508925 1.07 ENST00000534863.1
ENST00000383843.5
ENST00000458465.2
ENST00000405420.2
ENST00000272902.5
sulfatase modifying factor 1
chrX_-_102565932 1.07 ENST00000372674.1
ENST00000372677.3
brain expressed X-linked 2
chr9_-_123476612 1.06 ENST00000426959.1
multiple EGF-like-domains 9
chr17_+_62223320 1.06 ENST00000580828.1
ENST00000582965.1
small nucleolar RNA, H/ACA box 76
chr3_+_148847371 1.05 ENST00000296051.2
ENST00000460120.1
Hermansky-Pudlak syndrome 3
chr7_+_1094921 1.05 ENST00000397095.1
G protein-coupled receptor 146
chr14_-_88459503 1.04 ENST00000393568.4
ENST00000261304.2
galactosylceramidase
chr5_+_122110691 1.03 ENST00000379516.2
ENST00000505934.1
ENST00000514949.1
sorting nexin 2
chr3_+_127317066 1.03 ENST00000265056.7
minichromosome maintenance complex component 2
chr11_-_18343669 1.02 ENST00000396253.3
ENST00000349215.3
ENST00000438420.2
Hermansky-Pudlak syndrome 5
chr9_+_131709966 1.02 ENST00000372577.2
nucleoporin 188kDa
chr7_+_12726474 1.02 ENST00000396662.1
ENST00000356797.3
ENST00000396664.2
ADP-ribosylation factor-like 4A
chr3_+_112280857 1.02 ENST00000492406.1
ENST00000468642.1
solute carrier family 35, member A5
chr22_-_36903069 1.01 ENST00000216187.6
ENST00000423980.1
FAD-dependent oxidoreductase domain containing 2
chr19_-_48018203 1.01 ENST00000595227.1
ENST00000593761.1
ENST00000263354.3
N-ethylmaleimide-sensitive factor attachment protein, alpha
chr10_-_105452917 1.01 ENST00000427662.2
SH3 and PX domains 2A
chr8_-_103668114 1.01 ENST00000285407.6
Kruppel-like factor 10
chr6_-_33385823 1.01 ENST00000494751.1
ENST00000374496.3
cutA divalent cation tolerance homolog (E. coli)
chr2_+_109204743 1.00 ENST00000332345.6
LIM and senescent cell antigen-like domains 1
chr20_-_36156125 1.00 ENST00000397135.1
ENST00000397137.1
bladder cancer associated protein
chr3_+_5020801 1.00 ENST00000256495.3
basic helix-loop-helix family, member e40
chr14_-_20923195 0.99 ENST00000206542.4
O-sialoglycoprotein endopeptidase
chr15_-_72668185 0.99 ENST00000457859.2
ENST00000566304.1
ENST00000567159.1
ENST00000429918.2
hexosaminidase A (alpha polypeptide)
chr6_-_33385870 0.97 ENST00000488034.1
cutA divalent cation tolerance homolog (E. coli)
chr10_+_69644404 0.96 ENST00000212015.6
sirtuin 1
chr19_+_13049413 0.95 ENST00000316448.5
ENST00000588454.1
calreticulin
chr17_+_61562201 0.95 ENST00000290863.6
ENST00000413513.3
ENST00000421982.2
angiotensin I converting enzyme
chr7_-_38948774 0.95 ENST00000395969.2
ENST00000414632.1
ENST00000310301.4
vacuolar protein sorting 41 homolog (S. cerevisiae)
chr6_-_33385854 0.94 ENST00000488478.1
cutA divalent cation tolerance homolog (E. coli)
chr18_-_46987000 0.94 ENST00000442713.2
ENST00000269445.6
dymeclin
chr11_+_18343800 0.93 ENST00000453096.2
general transcription factor IIH, polypeptide 1, 62kDa
chr17_-_26989136 0.93 ENST00000247020.4
stromal cell-derived factor 2
chr6_-_84937314 0.92 ENST00000257766.4
ENST00000403245.3
KIAA1009
chr14_+_96505659 0.92 ENST00000555004.1
chromosome 14 open reading frame 132
chr6_-_33385902 0.92 ENST00000374500.5
cutA divalent cation tolerance homolog (E. coli)
chrX_+_102883620 0.91 ENST00000372626.3
transcription elongation factor A (SII)-like 1
chr12_-_65153175 0.90 ENST00000543646.1
ENST00000542058.1
ENST00000258145.3
glucosamine (N-acetyl)-6-sulfatase
chr6_+_123110465 0.89 ENST00000539041.1
sphingomyelin phosphodiesterase, acid-like 3A
chr19_-_45681482 0.88 ENST00000592647.1
ENST00000006275.4
ENST00000588062.1
ENST00000585934.1
trafficking protein particle complex 6A
chr9_-_111775772 0.88 ENST00000325580.6
ENST00000374593.4
ENST00000374595.4
ENST00000325551.4
catenin (cadherin-associated protein), alpha-like 1
chr1_+_45477901 0.88 ENST00000434478.1
uroporphyrinogen decarboxylase
chr19_+_1407733 0.87 ENST00000592453.1
DAZ associated protein 1
chr20_-_36156293 0.86 ENST00000373537.2
ENST00000414542.2
bladder cancer associated protein
chr6_-_33385655 0.86 ENST00000440279.3
ENST00000607266.1
cutA divalent cation tolerance homolog (E. coli)
chr20_-_2821271 0.85 ENST00000448755.1
ENST00000360652.2
PC-esterase domain containing 1A
chr11_+_126081662 0.85 ENST00000528985.1
ENST00000529731.1
ENST00000360194.4
ENST00000530043.1
family with sequence similarity 118, member B
chr6_-_31830655 0.85 ENST00000375631.4
sialidase 1 (lysosomal sialidase)
chr2_+_109204909 0.85 ENST00000393310.1
LIM and senescent cell antigen-like domains 1
chr5_+_43603229 0.84 ENST00000344920.4
ENST00000512996.2
nicotinamide nucleotide transhydrogenase
chr17_-_57184260 0.84 ENST00000376149.3
ENST00000393066.3
tripartite motif containing 37
chrX_+_102631248 0.84 ENST00000361298.4
ENST00000372645.3
ENST00000372635.1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr5_-_14871866 0.84 ENST00000284268.6
ANKH inorganic pyrophosphate transport regulator
chr15_+_44084040 0.83 ENST00000249786.4
small EDRK-rich factor 2
chr9_+_130860810 0.83 ENST00000433501.1
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr4_-_74964904 0.83 ENST00000508487.2
chemokine (C-X-C motif) ligand 2
chr8_+_98900132 0.83 ENST00000520016.1
matrilin 2
chr22_-_39637135 0.82 ENST00000440375.1
platelet-derived growth factor beta polypeptide
chr6_+_123110302 0.82 ENST00000368440.4
sphingomyelin phosphodiesterase, acid-like 3A
chr20_-_2821756 0.82 ENST00000356872.3
ENST00000439542.1
PC-esterase domain containing 1A
chr7_+_16793160 0.82 ENST00000262067.4
tetraspanin 13
chr10_-_126849588 0.81 ENST00000411419.2
C-terminal binding protein 2
chr17_+_61562178 0.81 ENST00000490216.2
angiotensin I converting enzyme
chr10_-_46090334 0.80 ENST00000395771.3
ENST00000319836.3
membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
chr7_+_142919130 0.80 ENST00000408947.3
taste receptor, type 2, member 40
chrX_-_100914781 0.80 ENST00000431597.1
ENST00000458024.1
ENST00000413506.1
ENST00000440675.1
ENST00000328766.5
ENST00000356824.4
armadillo repeat containing, X-linked 2
chr1_-_11865982 0.80 ENST00000418034.1
methylenetetrahydrofolate reductase (NAD(P)H)
chr18_+_48918368 0.79 ENST00000583982.1
ENST00000578152.1
ENST00000583609.1
ENST00000435144.1
ENST00000580841.1
RP11-267C16.1
chr9_+_130860583 0.79 ENST00000373064.5
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr21_-_38445470 0.79 ENST00000399098.1
phosphatidylinositol glycan anchor biosynthesis, class P
chr6_+_127587755 0.79 ENST00000368314.1
ENST00000476956.1
ENST00000609447.1
ENST00000356799.2
ENST00000477776.1
ENST00000609944.1
ring finger protein 146
chr3_+_158519654 0.78 ENST00000415822.2
ENST00000392813.4
ENST00000264266.8
major facilitator superfamily domain containing 1
chr6_+_148663729 0.78 ENST00000367467.3
SAM and SH3 domain containing 1
chr9_+_72002837 0.78 ENST00000377216.3
family with sequence similarity 189, member A2
chr1_-_154909329 0.77 ENST00000368467.3
phosphomevalonate kinase
chr17_+_42977122 0.76 ENST00000412523.2
ENST00000331733.4
ENST00000417826.2
family with sequence similarity 187, member A
coiled-coil domain containing 103
chr8_-_95274536 0.76 ENST00000297596.2
ENST00000396194.2
GTP binding protein overexpressed in skeletal muscle
chr19_-_41256207 0.76 ENST00000598485.2
ENST00000470681.1
ENST00000339153.3
ENST00000598729.1
chromosome 19 open reading frame 54
chr11_-_6640585 0.76 ENST00000533371.1
ENST00000528657.1
ENST00000436873.2
ENST00000299427.6
tripeptidyl peptidase I
chrX_+_13671225 0.76 ENST00000545566.1
ENST00000544987.1
ENST00000314720.4
transcription elongation factor A (SII) N-terminal and central domain containing
chr4_+_159131346 0.76 ENST00000508243.1
ENST00000296529.6
transmembrane protein 144
chr3_-_142720267 0.76 ENST00000597953.1
RP11-91G21.1
chr7_-_27196267 0.75 ENST00000242159.3
homeobox A7
chr1_+_76540386 0.75 ENST00000328299.3
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr2_+_46524537 0.75 ENST00000263734.3
endothelial PAS domain protein 1
chr4_-_77134742 0.75 ENST00000452464.2
scavenger receptor class B, member 2

Network of associatons between targets according to the STRING database.

First level regulatory network of SREBF1_TFE3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.5 GO:0002086 diaphragm contraction(GO:0002086)
1.3 5.3 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
1.0 7.1 GO:0097338 response to clozapine(GO:0097338)
0.8 2.5 GO:1904481 response to tetrahydrofolate(GO:1904481) cellular response to tetrahydrofolate(GO:1904482)
0.8 2.5 GO:0061150 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.8 3.8 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.7 2.0 GO:0015728 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.6 5.2 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.6 1.8 GO:0071284 cellular response to lead ion(GO:0071284)
0.6 1.7 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.5 2.0 GO:0090677 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.5 3.5 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.5 1.4 GO:0015680 intracellular copper ion transport(GO:0015680)
0.5 1.4 GO:0034146 B-1 B cell homeostasis(GO:0001922) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947) negative regulation of osteoclast proliferation(GO:0090291)
0.4 1.8 GO:1903597 negative regulation of gap junction assembly(GO:1903597)
0.4 1.7 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.4 1.3 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.4 1.3 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.4 3.4 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.4 1.1 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) regulation of chromatin silencing at telomere(GO:0031938) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.3 1.4 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.3 1.0 GO:0035494 SNARE complex disassembly(GO:0035494)
0.3 1.0 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.3 2.3 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.3 1.3 GO:1905123 regulation of endosome organization(GO:1904978) regulation of glucosylceramidase activity(GO:1905123)
0.3 1.0 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.3 0.9 GO:0060178 regulation of exocyst assembly(GO:0001928) regulation of exocyst localization(GO:0060178)
0.3 9.0 GO:0010669 epithelial structure maintenance(GO:0010669)
0.3 3.5 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.3 0.8 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.3 1.9 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.3 1.6 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.3 1.1 GO:1904448 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.3 0.8 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.3 4.8 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.2 1.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.2 0.7 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.2 0.7 GO:0060435 bronchiole development(GO:0060435)
0.2 1.1 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.2 0.7 GO:0051596 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.2 1.1 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.2 2.3 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.2 4.7 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.2 1.3 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.2 1.3 GO:0070560 protein secretion by platelet(GO:0070560)
0.2 0.9 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.2 1.1 GO:0006740 NADPH regeneration(GO:0006740)
0.2 0.6 GO:0061582 intestinal epithelial cell migration(GO:0061582)
0.2 1.9 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.2 0.6 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.2 2.1 GO:1900044 regulation of protein K63-linked ubiquitination(GO:1900044)
0.2 0.8 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 1.1 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.2 0.7 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.2 0.9 GO:0036369 transcription factor catabolic process(GO:0036369)
0.2 0.7 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.2 0.5 GO:0006566 threonine metabolic process(GO:0006566)
0.2 1.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.2 0.9 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.2 0.5 GO:0036509 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.2 0.8 GO:0021553 olfactory nerve development(GO:0021553)
0.2 1.0 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.2 1.5 GO:0015889 cobalamin transport(GO:0015889)
0.2 1.0 GO:0060620 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.2 2.0 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.2 4.8 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.2 0.5 GO:0042727 flavin-containing compound biosynthetic process(GO:0042727)
0.2 0.5 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.2 0.5 GO:0060545 positive regulation of necroptotic process(GO:0060545)
0.2 0.6 GO:0035509 negative regulation of myosin-light-chain-phosphatase activity(GO:0035509) negative regulation of bicellular tight junction assembly(GO:1903347)
0.2 1.0 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
0.2 0.6 GO:0005985 sucrose metabolic process(GO:0005985)
0.2 3.1 GO:0051503 adenine nucleotide transport(GO:0051503)
0.2 1.9 GO:0042908 xenobiotic transport(GO:0042908)
0.2 1.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.2 0.5 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1 0.7 GO:0043129 surfactant homeostasis(GO:0043129)
0.1 0.3 GO:0070827 chromatin maintenance(GO:0070827)
0.1 1.3 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.1 1.9 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.7 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 1.4 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.5 GO:0016139 glycoside catabolic process(GO:0016139)
0.1 1.7 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.1 0.4 GO:2000308 iron assimilation(GO:0033212) iron assimilation by chelation and transport(GO:0033214) positive regulation of bone mineralization involved in bone maturation(GO:1900159) negative regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000308)
0.1 0.5 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.1 1.2 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 1.1 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.1 0.4 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 0.6 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.1 0.5 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.1 0.1 GO:1904379 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.1 0.8 GO:1903232 melanosome assembly(GO:1903232)
0.1 0.5 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 0.5 GO:2001153 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.1 1.0 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.1 0.6 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.1 1.7 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.3 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.1 0.6 GO:0072553 terminal button organization(GO:0072553)
0.1 0.5 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.1 1.0 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.1 0.4 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.1 2.1 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.1 1.0 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.1 0.4 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.1 0.9 GO:0046479 glycolipid catabolic process(GO:0019377) glycosphingolipid catabolic process(GO:0046479)
0.1 2.4 GO:0007035 vacuolar acidification(GO:0007035)
0.1 0.4 GO:0042823 pyridoxal phosphate biosynthetic process(GO:0042823)
0.1 3.3 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.1 0.3 GO:0061114 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.1 0.4 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.1 0.4 GO:1902908 regulation of melanosome transport(GO:1902908)
0.1 1.8 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.1 0.3 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.1 0.3 GO:0002384 hepatic immune response(GO:0002384)
0.1 0.5 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.1 1.1 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 2.3 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.1 1.1 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.1 0.8 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.1 2.3 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1 0.6 GO:0044789 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.1 1.2 GO:0042118 endothelial cell activation(GO:0042118)
0.1 0.4 GO:0002572 pro-T cell differentiation(GO:0002572)
0.1 0.8 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 0.3 GO:0046832 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.1 0.3 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) histone H4-K12 acetylation(GO:0043983)
0.1 1.5 GO:0045008 depyrimidination(GO:0045008)
0.1 0.3 GO:0035552 oxidative single-stranded DNA demethylation(GO:0035552)
0.1 2.0 GO:0002021 response to dietary excess(GO:0002021)
0.1 1.5 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.1 0.3 GO:0070904 L-ascorbic acid transport(GO:0015882) molecular hydrogen transport(GO:0015993) transepithelial L-ascorbic acid transport(GO:0070904)
0.1 1.2 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.1 0.4 GO:0048733 sebaceous gland development(GO:0048733)
0.1 0.8 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.1 0.3 GO:0070495 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.1 0.2 GO:0016999 antibiotic metabolic process(GO:0016999) detoxification of mercury ion(GO:0050787)
0.1 1.4 GO:0036109 alpha-linolenic acid metabolic process(GO:0036109)
0.1 0.4 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.1 0.3 GO:0043335 protein unfolding(GO:0043335)
0.1 0.2 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.1 0.4 GO:1904977 lymphatic endothelial cell migration(GO:1904977)
0.1 0.2 GO:2000854 positive regulation of corticosterone secretion(GO:2000854)
0.1 0.7 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 0.4 GO:1901896 positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.1 0.3 GO:0034093 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.1 0.8 GO:0015886 heme transport(GO:0015886)
0.1 0.6 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.1 0.2 GO:0035674 tricarboxylic acid transmembrane transport(GO:0035674)
0.1 0.9 GO:0030575 nuclear body organization(GO:0030575)
0.1 0.2 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.1 3.3 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
0.1 0.2 GO:1904578 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.1 0.4 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 0.4 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.1 1.1 GO:0070987 error-free translesion synthesis(GO:0070987)
0.1 0.1 GO:0010157 response to chlorate(GO:0010157)
0.1 0.1 GO:0031291 Ran protein signal transduction(GO:0031291)
0.1 0.3 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.1 0.4 GO:0048505 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.1 0.2 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
0.1 0.3 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.1 4.3 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.1 0.3 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.1 0.4 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.3 GO:0061517 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.1 0.2 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 2.9 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.1 0.4 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
0.1 0.1 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.1 0.3 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.0 1.2 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.4 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.6 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 1.2 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.0 1.5 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 1.3 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.6 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0 0.2 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072)
0.0 0.3 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.7 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.4 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.2 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.1 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.0 0.2 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.8 GO:0006677 glycosylceramide metabolic process(GO:0006677)
0.0 1.8 GO:1904031 positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.2 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 0.7 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.2 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.4 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 1.8 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 0.7 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.8 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0 0.5 GO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
0.0 0.1 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.0 0.5 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 0.2 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.3 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.3 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.4 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 3.8 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 1.5 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.0 0.2 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0 0.3 GO:0051451 myoblast migration(GO:0051451)
0.0 0.1 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
0.0 1.6 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.0 4.9 GO:0030183 B cell differentiation(GO:0030183)
0.0 1.1 GO:0097421 liver regeneration(GO:0097421)
0.0 0.9 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.1 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.0 0.8 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.1 GO:0019087 transformation of host cell by virus(GO:0019087)
0.0 0.2 GO:1905244 regulation of modification of synaptic structure(GO:1905244)
0.0 0.5 GO:0044351 macropinocytosis(GO:0044351)
0.0 0.2 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.1 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.0 0.2 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.0 0.1 GO:1903935 response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.0 0.1 GO:0090675 intermicrovillar adhesion(GO:0090675)
0.0 0.1 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0 0.2 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.2 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.3 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.9 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.1 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.0 0.3 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0 0.1 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.0 0.3 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.2 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 0.1 GO:0006059 hexitol metabolic process(GO:0006059)
0.0 2.4 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.2 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 1.2 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.1 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.0 0.3 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.1 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.0 0.2 GO:0021903 rostrocaudal neural tube patterning(GO:0021903)
0.0 0.2 GO:0009624 response to nematode(GO:0009624)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.2 GO:0045475 locomotor rhythm(GO:0045475)
0.0 1.0 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.4 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 1.0 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.1 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
0.0 0.3 GO:0006768 biotin metabolic process(GO:0006768)
0.0 0.1 GO:0006500 N-terminal protein palmitoylation(GO:0006500)
0.0 0.5 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.0 0.4 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.0 0.5 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.1 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.0 0.1 GO:0019605 benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
0.0 0.1 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 3.0 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 1.8 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.3 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.0 0.3 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.0 0.3 GO:2000318 positive regulation of T-helper 17 type immune response(GO:2000318)
0.0 0.7 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.6 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.1 GO:0010635 regulation of mitochondrial fusion(GO:0010635)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.4 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.0 0.1 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.2 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.0 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.0 0.1 GO:2000828 parathyroid hormone secretion(GO:0035898) post-embryonic body morphogenesis(GO:0040032) regulation of parathyroid hormone secretion(GO:2000828)
0.0 0.0 GO:0043317 regulation of cytotoxic T cell degranulation(GO:0043317) negative regulation of cytotoxic T cell degranulation(GO:0043318)
0.0 0.0 GO:0007354 zygotic determination of anterior/posterior axis, embryo(GO:0007354)
0.0 0.6 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.1 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.6 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.1 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.2 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256)
0.0 0.9 GO:0007129 synapsis(GO:0007129)
0.0 0.2 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.0 0.6 GO:0048713 regulation of oligodendrocyte differentiation(GO:0048713)
0.0 0.4 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 0.2 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.0 0.2 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.3 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.1 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 3.6 GO:0031424 keratinization(GO:0031424)
0.0 0.4 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.1 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.3 GO:0007567 parturition(GO:0007567)
0.0 0.1 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.2 GO:0043586 tongue development(GO:0043586)
0.0 0.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.2 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.0 1.7 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.2 GO:0061318 renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112)
0.0 1.4 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.8 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.2 GO:1901798 positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0 0.8 GO:0008347 glial cell migration(GO:0008347)
0.0 0.0 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.1 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.0 0.7 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.3 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.0 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.6 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.6 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.1 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.0 0.1 GO:0030091 protein repair(GO:0030091)
0.0 0.2 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.1 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.2 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0 0.2 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.2 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0002860 positive regulation of response to tumor cell(GO:0002836) positive regulation of immune response to tumor cell(GO:0002839) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.1 GO:0046689 response to mercury ion(GO:0046689)
0.0 0.1 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.2 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.0 0.3 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.4 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.0 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.0 0.4 GO:0046676 negative regulation of insulin secretion(GO:0046676)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.5 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.7 2.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.6 3.7 GO:0033263 CORVET complex(GO:0033263)
0.5 4.0 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.5 2.8 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.4 2.7 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.4 1.1 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.3 1.7 GO:0035838 growing cell tip(GO:0035838)
0.3 7.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.3 0.3 GO:0019034 viral replication complex(GO:0019034)
0.3 1.1 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.3 1.0 GO:0044611 nuclear pore inner ring(GO:0044611)
0.3 1.0 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.2 1.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.2 1.1 GO:1990246 uniplex complex(GO:1990246)
0.2 1.9 GO:0071986 Ragulator complex(GO:0071986)
0.2 1.0 GO:0033553 rDNA heterochromatin(GO:0033553)
0.2 1.6 GO:0030896 checkpoint clamp complex(GO:0030896)
0.2 2.6 GO:0005641 nuclear envelope lumen(GO:0005641)
0.2 1.0 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.2 2.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.2 0.6 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 1.0 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 1.0 GO:0030905 retromer, tubulation complex(GO:0030905)
0.1 0.5 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.1 0.4 GO:0010009 cytoplasmic side of endosome membrane(GO:0010009)
0.1 19.2 GO:0043202 lysosomal lumen(GO:0043202)
0.1 0.5 GO:0055087 Ski complex(GO:0055087)
0.1 0.6 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.1 1.2 GO:0016589 NURF complex(GO:0016589)
0.1 0.4 GO:0030849 autosome(GO:0030849)
0.1 0.4 GO:0019031 viral envelope(GO:0019031) viral membrane(GO:0036338)
0.1 0.4 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.1 0.7 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 0.4 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.1 1.6 GO:0042555 MCM complex(GO:0042555)
0.1 0.4 GO:1990742 microvesicle(GO:1990742)
0.1 2.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 1.0 GO:0000439 core TFIIH complex(GO:0000439)
0.1 0.8 GO:0097470 ribbon synapse(GO:0097470)
0.1 0.3 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.1 0.7 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.1 0.5 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 0.3 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 1.4 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.1 0.3 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.1 0.5 GO:0044294 dendritic growth cone(GO:0044294)
0.1 0.5 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.8 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 0.8 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 0.2 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 0.2 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 0.6 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 4.9 GO:0045095 keratin filament(GO:0045095)
0.1 1.3 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.1 0.4 GO:0044279 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279) phagocytic vesicle lumen(GO:0097013)
0.1 2.7 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.1 0.2 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.1 0.9 GO:0030008 TRAPP complex(GO:0030008)
0.1 0.5 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 0.4 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 0.3 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.1 1.8 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.2 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.2 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 2.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.6 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.5 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 1.1 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 3.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.3 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.3 GO:0070695 FHF complex(GO:0070695)
0.0 1.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.4 GO:0000801 central element(GO:0000801)
0.0 1.3 GO:0000145 exocyst(GO:0000145)
0.0 1.0 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.0 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 3.2 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 3.9 GO:0005901 caveola(GO:0005901)
0.0 0.7 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.3 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.1 GO:1990812 growth cone filopodium(GO:1990812)
0.0 0.8 GO:0010369 chromocenter(GO:0010369)
0.0 6.2 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.6 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 3.4 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.2 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.2 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0 2.9 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.1 GO:0000805 X chromosome(GO:0000805) Barr body(GO:0001740)
0.0 0.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.1 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.3 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.3 GO:0097418 neurofibrillary tangle(GO:0097418)
0.0 0.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 10.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.0 0.8 GO:0051233 spindle midzone(GO:0051233)
0.0 0.7 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.1 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.5 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.5 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.2 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.3 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.2 GO:0005915 zonula adherens(GO:0005915)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.4 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.2 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:1990357 terminal web(GO:1990357)
0.0 1.8 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.2 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.4 GO:0031904 endosome lumen(GO:0031904)
0.0 1.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.0 GO:0002102 podosome(GO:0002102)
0.0 0.3 GO:0097440 apical dendrite(GO:0097440)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.4 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 1.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 1.3 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.6 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.0 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.2 GO:0097342 ripoptosome(GO:0097342)
0.0 0.2 GO:0031105 septin complex(GO:0031105)
0.0 0.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.5 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.9 9.6 GO:0030274 LIM domain binding(GO:0030274)
0.7 2.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.7 4.2 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.7 2.0 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.6 1.8 GO:0032767 copper-dependent protein binding(GO:0032767)
0.5 1.6 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.5 1.6 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.5 2.5 GO:0070905 serine binding(GO:0070905)
0.5 1.9 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.4 1.7 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.4 2.5 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.4 1.9 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.4 1.1 GO:0004103 choline kinase activity(GO:0004103)
0.4 1.1 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.4 1.8 GO:0017040 ceramidase activity(GO:0017040)
0.4 1.1 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.3 1.0 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.3 3.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.3 1.4 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.3 1.0 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.3 1.3 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.3 3.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.3 3.5 GO:0050544 arachidonic acid binding(GO:0050544)
0.3 5.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.3 1.1 GO:0047298 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.3 3.4 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.3 0.8 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.3 1.5 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2 3.0 GO:0031386 protein tag(GO:0031386)
0.2 1.0 GO:0043398 HLH domain binding(GO:0043398)
0.2 1.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.2 0.7 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.2 0.9 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.2 3.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.2 0.7 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.2 2.3 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.2 1.9 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.2 1.0 GO:1990460 leptin receptor binding(GO:1990460)
0.2 2.5 GO:0070700 co-receptor binding(GO:0039706) BMP receptor binding(GO:0070700)
0.2 2.3 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.2 0.5 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.2 3.1 GO:0005346 adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.2 0.9 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.2 0.8 GO:0005166 neurotrophin p75 receptor binding(GO:0005166) nerve growth factor receptor activity(GO:0010465)
0.2 1.3 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.2 1.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.2 0.5 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.2 0.6 GO:0008384 IkappaB kinase activity(GO:0008384)
0.2 0.6 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.2 0.9 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.2 2.0 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.2 0.9 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.4 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.4 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.1 0.7 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 0.4 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.1 0.6 GO:0036033 mediator complex binding(GO:0036033)
0.1 0.4 GO:0051990 (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.1 0.9 GO:0052794 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1 0.6 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1 0.7 GO:0004925 prolactin receptor activity(GO:0004925)
0.1 1.5 GO:0031419 cobalamin binding(GO:0031419)
0.1 1.2 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.4 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.1 1.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.5 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.1 0.7 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.5 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.1 0.8 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 0.3 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.1 1.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.3 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.1 0.4 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.1 1.0 GO:0043426 MRF binding(GO:0043426)
0.1 0.5 GO:0016453 C-acetyltransferase activity(GO:0016453)
0.1 2.6 GO:0036442 hydrogen-exporting ATPase activity(GO:0036442) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 0.8 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 2.4 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 1.0 GO:0001849 complement component C1q binding(GO:0001849)
0.1 2.9 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 2.0 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.7 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 1.8 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.1 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.1 0.3 GO:0004915 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.1 0.5 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 1.6 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 0.4 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 0.5 GO:0005119 smoothened binding(GO:0005119)
0.1 0.3 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.1 0.7 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.3 GO:0035514 DNA demethylase activity(GO:0035514)
0.1 0.3 GO:0008523 L-ascorbate:sodium symporter activity(GO:0008520) sodium-dependent multivitamin transmembrane transporter activity(GO:0008523) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.1 0.4 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.1 0.3 GO:0047708 biotinidase activity(GO:0047708)
0.1 0.4 GO:0010181 FMN binding(GO:0010181)
0.1 0.6 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 1.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.2 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.1 0.3 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.1 0.5 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 0.3 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 0.2 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.1 2.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 0.3 GO:0004802 transketolase activity(GO:0004802)
0.1 0.6 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 0.4 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.1 0.1 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.1 1.7 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 4.2 GO:0050699 WW domain binding(GO:0050699)
0.1 0.2 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 0.5 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 0.6 GO:0048039 ubiquinone binding(GO:0048039)
0.1 0.3 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.1 0.6 GO:0051425 PTB domain binding(GO:0051425)
0.1 1.0 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 0.5 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.1 0.4 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 0.2 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.1 0.3 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.3 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.3 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.1 0.8 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.3 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.2 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.2 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.1 0.3 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.0 2.6 GO:0044390 ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 0.2 GO:0052839 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.6 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 0.3 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.0 0.3 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.9 GO:0005351 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0 0.5 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.5 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.2 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.7 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 1.0 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.2 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.2 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.1 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.6 GO:0015929 hexosaminidase activity(GO:0015929)
0.0 0.3 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.2 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 0.3 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.2 GO:0051800 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314) phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.0 0.8 GO:0070878 primary miRNA binding(GO:0070878)
0.0 0.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 3.1 GO:0043621 protein self-association(GO:0043621)
0.0 1.1 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.5 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 6.3 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.3 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.4 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.1 GO:0016160 amylase activity(GO:0016160)
0.0 0.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 3.3 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 1.4 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.2 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.9 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.2 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.4 GO:0035240 dopamine binding(GO:0035240)
0.0 0.6 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.7 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 3.1 GO:0050660 flavin adenine dinucleotide binding(GO:0050660)
0.0 0.2 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 1.2 GO:1901476 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.0 0.3 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 2.5 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.0 0.6 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.3 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.9 GO:0008009 chemokine activity(GO:0008009)
0.0 0.2 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.3 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0004960 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0 1.7 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0 0.4 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 1.0 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.2 GO:0001016 RNA polymerase III regulatory region DNA binding(GO:0001016)
0.0 0.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.3 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.1 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.4 GO:0005542 folic acid binding(GO:0005542)
0.0 0.3 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.9 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.4 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 2.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.1 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.5 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.4 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.6 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 0.2 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.3 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.0 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.1 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.0 GO:0034038 deoxyhypusine synthase activity(GO:0034038)
0.0 0.3 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.1 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.0 0.3 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.2 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0 8.5 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.2 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.0 0.1 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.3 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.0 1.2 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 0.0 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.3 GO:0017166 vinculin binding(GO:0017166)
0.0 0.3 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.1 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.0 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.0 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.0 0.1 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 0.2 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.8 GO:0005507 copper ion binding(GO:0005507)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.8 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 7.1 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 4.6 PID IL3 PATHWAY IL3-mediated signaling events
0.1 0.6 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.1 0.9 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 3.0 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.1 2.0 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 1.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 2.9 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 0.8 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 1.8 PID S1P S1P1 PATHWAY S1P1 pathway
0.1 0.7 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 3.8 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 0.6 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 4.0 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.0 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 2.2 PID ATR PATHWAY ATR signaling pathway
0.0 1.9 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 1.3 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.1 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.9 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 2.6 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 1.0 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.3 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.9 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 1.0 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 1.9 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.1 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.3 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.6 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.8 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.8 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.2 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.4 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.3 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.2 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.9 PID BMP PATHWAY BMP receptor signaling
0.0 1.1 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.0 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.5 PID P73PATHWAY p73 transcription factor network
0.0 0.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.4 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.2 5.6 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2 2.7 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 2.7 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 7.1 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 0.3 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.1 1.6 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 2.2 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 0.4 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 2.0 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 2.1 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 2.8 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 3.8 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 2.3 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 1.9 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.4 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 0.4 REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
0.1 1.4 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 1.7 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 1.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 4.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 1.2 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 0.8 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.1 1.5 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.1 2.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 1.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 5.0 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0 1.3 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 1.3 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 1.6 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 1.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 1.8 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 4.5 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.7 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 1.9 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.7 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 2.3 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.1 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 1.0 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.2 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.6 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.4 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 1.3 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.6 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 1.7 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 1.1 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.5 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.8 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.3 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 1.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.8 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.3 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.5 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.7 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.1 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 2.3 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.3 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.1 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.1 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.7 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.2 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.4 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.5 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1