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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for SRY

Z-value: 0.67

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Transcription factors associated with SRY

Gene Symbol Gene ID Gene Info
SRY
ENSG00000184895.6 sex determining region Y

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SRYhg19_v2_chrY_-_2655644_2655740-0.252.3e-01Click!

Activity profile of SRY motif

Sorted Z-values of SRY motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_41614909 1.90 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1
LIM and calponin homology domains 1
chr4_+_41614720 1.80 ENST00000509277.1
LIMCH1
LIM and calponin homology domains 1
chr5_-_111091948 1.77 ENST00000447165.2
NREP
neuronal regeneration related protein
chr2_+_228678550 1.59 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr14_-_92414055 1.47 ENST00000342058.4
FBLN5
fibulin 5
chr14_-_92413353 1.33 ENST00000556154.1
FBLN5
fibulin 5
chr1_+_61547405 1.30 ENST00000371189.4
NFIA
nuclear factor I/A
chr13_-_114843416 1.10 ENST00000389544.4
RASA3
RAS p21 protein activator 3
chr15_-_59665062 1.09 ENST00000288235.4
MYO1E
myosin IE
chr11_-_10830463 1.02 ENST00000527419.1
ENST00000530211.1
ENST00000530702.1
ENST00000524932.1
ENST00000532570.1
EIF4G2
eukaryotic translation initiation factor 4 gamma, 2
chr1_+_84630053 0.97 ENST00000394838.2
ENST00000370682.3
ENST00000432111.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr1_+_84630645 0.94 ENST00000394839.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr7_+_134551583 0.89 ENST00000435928.1
CALD1
caldesmon 1
chr1_-_85930246 0.89 ENST00000426972.3
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr2_-_208030647 0.87 ENST00000309446.6
KLF7
Kruppel-like factor 7 (ubiquitous)
chr14_-_92413727 0.79 ENST00000267620.10
FBLN5
fibulin 5
chr1_+_164528866 0.77 ENST00000420696.2
PBX1
pre-B-cell leukemia homeobox 1
chr18_+_3448455 0.69 ENST00000549780.1
TGIF1
TGFB-induced factor homeobox 1
chr2_+_208423891 0.68 ENST00000448277.1
ENST00000457101.1
CREB1
cAMP responsive element binding protein 1
chr21_+_33784670 0.67 ENST00000300255.2
EVA1C
eva-1 homolog C (C. elegans)
chr9_-_14314566 0.66 ENST00000397579.2
NFIB
nuclear factor I/B
chr9_-_14314518 0.66 ENST00000397581.2
NFIB
nuclear factor I/B
chr17_-_67138015 0.66 ENST00000284425.2
ENST00000590645.1
ABCA6
ATP-binding cassette, sub-family A (ABC1), member 6
chr14_-_51027838 0.66 ENST00000555216.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr1_-_57045228 0.62 ENST00000371250.3
PPAP2B
phosphatidic acid phosphatase type 2B
chr18_-_53303123 0.59 ENST00000569357.1
ENST00000565124.1
ENST00000398339.1
TCF4
transcription factor 4
chrX_+_84499081 0.57 ENST00000276123.3
ZNF711
zinc finger protein 711
chr15_-_34610962 0.57 ENST00000290209.5
SLC12A6
solute carrier family 12 (potassium/chloride transporter), member 6
chr3_-_141868293 0.57 ENST00000317104.7
ENST00000494358.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr1_+_159409512 0.54 ENST00000423932.3
OR10J1
olfactory receptor, family 10, subfamily J, member 1
chr18_-_52989217 0.53 ENST00000570287.2
TCF4
transcription factor 4
chr2_+_162087577 0.53 ENST00000439442.1
TANK
TRAF family member-associated NFKB activator
chr14_+_53019993 0.53 ENST00000542169.2
ENST00000555622.1
GPR137C
G protein-coupled receptor 137C
chr14_-_73493784 0.52 ENST00000553891.1
ZFYVE1
zinc finger, FYVE domain containing 1
chr2_-_157198860 0.51 ENST00000409572.1
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr11_-_10829851 0.50 ENST00000532082.1
EIF4G2
eukaryotic translation initiation factor 4 gamma, 2
chr9_-_123476719 0.49 ENST00000373930.3
MEGF9
multiple EGF-like-domains 9
chr1_+_97188188 0.48 ENST00000541987.1
PTBP2
polypyrimidine tract binding protein 2
chr15_-_70390213 0.48 ENST00000557997.1
ENST00000317509.8
ENST00000442299.2
TLE3
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr9_-_123476612 0.48 ENST00000426959.1
MEGF9
multiple EGF-like-domains 9
chr14_+_22748980 0.47 ENST00000390465.2
TRAV38-2DV8
T cell receptor alpha variable 38-2/delta variable 8
chr15_-_70994612 0.47 ENST00000558758.1
ENST00000379983.2
ENST00000560441.1
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr21_+_17792672 0.45 ENST00000602620.1
LINC00478
long intergenic non-protein coding RNA 478
chr14_-_73493825 0.44 ENST00000318876.5
ENST00000556143.1
ZFYVE1
zinc finger, FYVE domain containing 1
chr11_+_128563948 0.44 ENST00000534087.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr5_+_140743859 0.44 ENST00000518069.1
PCDHGA5
protocadherin gamma subfamily A, 5
chr14_-_23288930 0.43 ENST00000554517.1
ENST00000285850.7
ENST00000397529.2
ENST00000555702.1
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr9_-_16727978 0.43 ENST00000418777.1
ENST00000468187.2
BNC2
basonuclin 2
chr2_-_192711968 0.42 ENST00000304141.4
SDPR
serum deprivation response
chr2_+_109204743 0.42 ENST00000332345.6
LIMS1
LIM and senescent cell antigen-like domains 1
chr19_+_13906250 0.41 ENST00000254323.2
ZSWIM4
zinc finger, SWIM-type containing 4
chr3_-_71353892 0.40 ENST00000484350.1
FOXP1
forkhead box P1
chr1_-_160231451 0.40 ENST00000495887.1
DCAF8
DDB1 and CUL4 associated factor 8
chr8_+_67405755 0.39 ENST00000521495.1
C8orf46
chromosome 8 open reading frame 46
chr3_+_57882024 0.39 ENST00000494088.1
SLMAP
sarcolemma associated protein
chr11_+_128563652 0.37 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chrX_+_15525426 0.37 ENST00000342014.6
BMX
BMX non-receptor tyrosine kinase
chr1_+_66797687 0.36 ENST00000371045.5
ENST00000531025.1
ENST00000526197.1
PDE4B
phosphodiesterase 4B, cAMP-specific
chr1_+_84630367 0.36 ENST00000370680.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr19_+_13134772 0.36 ENST00000587760.1
ENST00000585575.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr18_+_3466248 0.35 ENST00000581029.1
ENST00000581442.1
ENST00000579007.1
RP11-838N2.4
RP11-838N2.4
chr2_-_160473114 0.34 ENST00000392783.2
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr3_-_141868357 0.33 ENST00000489671.1
ENST00000475734.1
ENST00000467072.1
ENST00000499676.2
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr18_-_52969844 0.33 ENST00000561831.3
TCF4
transcription factor 4
chr14_+_53019822 0.33 ENST00000321662.6
GPR137C
G protein-coupled receptor 137C
chr18_-_53257027 0.33 ENST00000568740.1
ENST00000564403.2
ENST00000537578.1
TCF4
transcription factor 4
chr14_-_89883412 0.32 ENST00000557258.1
FOXN3
forkhead box N3
chrX_+_84499038 0.31 ENST00000373165.3
ZNF711
zinc finger protein 711
chr18_+_3451584 0.31 ENST00000551541.1
TGIF1
TGFB-induced factor homeobox 1
chr5_+_138677515 0.30 ENST00000265192.4
ENST00000511706.1
PAIP2
poly(A) binding protein interacting protein 2
chr18_+_11851383 0.30 ENST00000526991.2
CHMP1B
charged multivesicular body protein 1B
chr11_-_111637083 0.30 ENST00000427203.2
ENST00000341980.6
ENST00000311129.5
ENST00000393055.2
ENST00000426998.2
ENST00000527614.1
PPP2R1B
protein phosphatase 2, regulatory subunit A, beta
chr4_-_76598544 0.29 ENST00000515457.1
ENST00000357854.3
G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr20_-_62582475 0.29 ENST00000369908.5
UCKL1
uridine-cytidine kinase 1-like 1
chr7_+_128399002 0.28 ENST00000493278.1
CALU
calumenin
chr4_+_170581213 0.28 ENST00000507875.1
CLCN3
chloride channel, voltage-sensitive 3
chr3_+_178866199 0.27 ENST00000263967.3
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
chr9_+_27109392 0.27 ENST00000406359.4
TEK
TEK tyrosine kinase, endothelial
chrX_+_28605516 0.27 ENST00000378993.1
IL1RAPL1
interleukin 1 receptor accessory protein-like 1
chr5_+_140739537 0.27 ENST00000522605.1
PCDHGB2
protocadherin gamma subfamily B, 2
chr2_-_160472952 0.27 ENST00000541068.2
ENST00000355831.2
ENST00000343439.5
ENST00000392782.1
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr1_+_205682497 0.27 ENST00000598338.1
AC119673.1
AC119673.1
chr22_+_19710468 0.26 ENST00000366425.3
GP1BB
glycoprotein Ib (platelet), beta polypeptide
chr14_+_91580777 0.26 ENST00000525393.2
ENST00000428926.2
ENST00000517362.1
C14orf159
chromosome 14 open reading frame 159
chr14_+_91581011 0.26 ENST00000523894.1
ENST00000522322.1
ENST00000523771.1
C14orf159
chromosome 14 open reading frame 159
chr2_+_191273052 0.26 ENST00000417958.1
ENST00000432036.1
ENST00000392328.1
MFSD6
major facilitator superfamily domain containing 6
chr17_-_40428359 0.26 ENST00000293328.3
STAT5B
signal transducer and activator of transcription 5B
chr11_+_128562372 0.26 ENST00000344954.6
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr13_-_74708372 0.24 ENST00000377666.4
KLF12
Kruppel-like factor 12
chr14_+_91580708 0.24 ENST00000518868.1
C14orf159
chromosome 14 open reading frame 159
chr19_+_13135731 0.24 ENST00000587260.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr3_-_28390298 0.24 ENST00000457172.1
AZI2
5-azacytidine induced 2
chr20_-_43150601 0.23 ENST00000541235.1
ENST00000255175.1
ENST00000342374.4
SERINC3
serine incorporator 3
chr7_+_29519486 0.23 ENST00000409041.4
CHN2
chimerin 2
chr8_+_67405794 0.23 ENST00000522977.1
ENST00000480005.1
C8orf46
chromosome 8 open reading frame 46
chr21_-_39870339 0.23 ENST00000429727.2
ENST00000398905.1
ENST00000398907.1
ENST00000453032.2
ENST00000288319.7
ERG
v-ets avian erythroblastosis virus E26 oncogene homolog
chr12_-_81763184 0.22 ENST00000548670.1
ENST00000541570.2
ENST00000553058.1
PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr1_+_33116765 0.22 ENST00000544435.1
ENST00000373485.1
ENST00000458695.2
ENST00000490500.1
ENST00000445722.2
RBBP4
retinoblastoma binding protein 4
chrX_-_39923656 0.22 ENST00000413905.1
BCOR
BCL6 corepressor
chr17_-_46716647 0.22 ENST00000608940.1
RP11-357H14.17
RP11-357H14.17
chr9_-_39239171 0.22 ENST00000358144.2
CNTNAP3
contactin associated protein-like 3
chr11_+_67007518 0.21 ENST00000530342.1
ENST00000308783.5
KDM2A
lysine (K)-specific demethylase 2A
chr14_+_22985251 0.21 ENST00000390510.1
TRAJ27
T cell receptor alpha joining 27
chr6_+_108882069 0.21 ENST00000406360.1
FOXO3
forkhead box O3
chr7_-_19813192 0.20 ENST00000422233.1
ENST00000433641.1
TMEM196
transmembrane protein 196
chr2_+_27665289 0.20 ENST00000407293.1
KRTCAP3
keratinocyte associated protein 3
chr11_-_82708435 0.20 ENST00000525117.1
ENST00000532548.1
RAB30
RAB30, member RAS oncogene family
chr18_+_3451646 0.20 ENST00000345133.5
ENST00000330513.5
ENST00000549546.1
TGIF1
TGFB-induced factor homeobox 1
chr5_-_11589131 0.20 ENST00000511377.1
CTNND2
catenin (cadherin-associated protein), delta 2
chr17_-_39324424 0.20 ENST00000391356.2
KRTAP4-3
keratin associated protein 4-3
chr2_-_231989808 0.20 ENST00000258400.3
HTR2B
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chrX_+_99839799 0.19 ENST00000373031.4
TNMD
tenomodulin
chr9_-_37465396 0.19 ENST00000307750.4
ZBTB5
zinc finger and BTB domain containing 5
chr10_+_111985713 0.18 ENST00000239007.7
MXI1
MAX interactor 1, dimerization protein
chr5_+_138678131 0.17 ENST00000394795.2
ENST00000510080.1
PAIP2
poly(A) binding protein interacting protein 2
chr7_+_30185406 0.17 ENST00000324489.5
C7orf41
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr3_-_28390415 0.17 ENST00000414162.1
ENST00000420543.2
AZI2
5-azacytidine induced 2
chr6_+_84563295 0.17 ENST00000369687.1
RIPPLY2
ripply transcriptional repressor 2
chr12_-_31477072 0.17 ENST00000454658.2
FAM60A
family with sequence similarity 60, member A
chr1_-_151119087 0.17 ENST00000341697.3
ENST00000368914.3
SEMA6C
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
chr20_-_3762087 0.17 ENST00000379756.3
SPEF1
sperm flagellar 1
chr11_-_118095801 0.17 ENST00000356289.5
AMICA1
adhesion molecule, interacts with CXADR antigen 1
chr20_-_61002584 0.16 ENST00000252998.1
RBBP8NL
RBBP8 N-terminal like
chr18_-_52989525 0.16 ENST00000457482.3
TCF4
transcription factor 4
chr14_+_91580732 0.16 ENST00000519019.1
ENST00000523816.1
ENST00000517518.1
C14orf159
chromosome 14 open reading frame 159
chr7_-_99698338 0.16 ENST00000354230.3
ENST00000425308.1
MCM7
minichromosome maintenance complex component 7
chr15_-_52263937 0.16 ENST00000315141.5
ENST00000299601.5
LEO1
Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr9_+_139874683 0.15 ENST00000444903.1
PTGDS
prostaglandin D2 synthase 21kDa (brain)
chr16_-_15736881 0.15 ENST00000540441.2
KIAA0430
KIAA0430
chr15_-_86338134 0.15 ENST00000337975.5
KLHL25
kelch-like family member 25
chr14_-_53019211 0.15 ENST00000557374.1
ENST00000281741.4
TXNDC16
thioredoxin domain containing 16
chr8_+_70404996 0.15 ENST00000402687.4
ENST00000419716.3
SULF1
sulfatase 1
chr15_-_86338100 0.15 ENST00000536947.1
KLHL25
kelch-like family member 25
chr4_-_103746683 0.14 ENST00000504211.1
ENST00000508476.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr1_-_93645818 0.14 ENST00000370280.1
ENST00000479918.1
TMED5
transmembrane emp24 protein transport domain containing 5
chr10_+_115312766 0.14 ENST00000351270.3
HABP2
hyaluronan binding protein 2
chr12_+_60058458 0.14 ENST00000548610.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr7_+_142985308 0.14 ENST00000310447.5
CASP2
caspase 2, apoptosis-related cysteine peptidase
chr12_-_56352368 0.14 ENST00000549404.1
PMEL
premelanosome protein
chr11_-_118095718 0.14 ENST00000526620.1
AMICA1
adhesion molecule, interacts with CXADR antigen 1
chr12_+_130646999 0.14 ENST00000539839.1
ENST00000229030.4
FZD10
frizzled family receptor 10
chr2_+_10262857 0.14 ENST00000304567.5
RRM2
ribonucleotide reductase M2
chr4_-_103746924 0.13 ENST00000505207.1
ENST00000502404.1
ENST00000507845.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr12_-_91451758 0.13 ENST00000266719.3
KERA
keratocan
chr7_+_29519662 0.13 ENST00000424025.2
ENST00000439711.2
ENST00000421775.2
CHN2
chimerin 2
chr17_+_79953310 0.13 ENST00000582355.2
ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr6_+_126070726 0.13 ENST00000368364.3
HEY2
hes-related family bHLH transcription factor with YRPW motif 2
chr12_+_50478977 0.13 ENST00000381513.4
SMARCD1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr12_-_10251539 0.12 ENST00000420265.2
CLEC1A
C-type lectin domain family 1, member A
chr15_-_55562582 0.12 ENST00000396307.2
RAB27A
RAB27A, member RAS oncogene family
chr19_-_46272462 0.12 ENST00000317578.6
SIX5
SIX homeobox 5
chr1_+_185703513 0.12 ENST00000271588.4
ENST00000367492.2
HMCN1
hemicentin 1
chr6_-_9939552 0.12 ENST00000460363.2
OFCC1
orofacial cleft 1 candidate 1
chr4_-_76598296 0.12 ENST00000395719.3
G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr3_+_57875711 0.11 ENST00000442599.2
SLMAP
sarcolemma associated protein
chr6_-_52109335 0.11 ENST00000336123.4
IL17F
interleukin 17F
chr20_+_10415931 0.11 ENST00000334534.5
SLX4IP
SLX4 interacting protein
chr5_-_146461027 0.11 ENST00000394410.2
ENST00000508267.1
ENST00000504198.1
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr3_-_11610255 0.11 ENST00000424529.2
VGLL4
vestigial like 4 (Drosophila)
chr3_+_28390637 0.10 ENST00000420223.1
ENST00000383768.2
ZCWPW2
zinc finger, CW type with PWWP domain 2
chr4_+_71263599 0.10 ENST00000399575.2
PROL1
proline rich, lacrimal 1
chr18_+_18943554 0.10 ENST00000580732.2
GREB1L
growth regulation by estrogen in breast cancer-like
chr3_-_28390120 0.10 ENST00000334100.6
AZI2
5-azacytidine induced 2
chr5_-_147162078 0.10 ENST00000507386.1
JAKMIP2
janus kinase and microtubule interacting protein 2
chr4_-_65275162 0.10 ENST00000381210.3
ENST00000507440.1
TECRL
trans-2,3-enoyl-CoA reductase-like
chr2_-_37899323 0.09 ENST00000295324.3
ENST00000457889.1
CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr6_+_105404899 0.09 ENST00000345080.4
LIN28B
lin-28 homolog B (C. elegans)
chr1_-_217311090 0.09 ENST00000493603.1
ENST00000366940.2
ESRRG
estrogen-related receptor gamma
chr12_-_498620 0.09 ENST00000399788.2
ENST00000382815.4
KDM5A
lysine (K)-specific demethylase 5A
chr13_+_102142296 0.09 ENST00000376162.3
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr3_-_178865747 0.09 ENST00000435560.1
RP11-360P21.2
RP11-360P21.2
chr13_-_41240717 0.09 ENST00000379561.5
FOXO1
forkhead box O1
chr15_-_55562479 0.09 ENST00000564609.1
RAB27A
RAB27A, member RAS oncogene family
chr4_-_103747011 0.08 ENST00000350435.7
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr6_+_31082603 0.08 ENST00000259881.9
PSORS1C1
psoriasis susceptibility 1 candidate 1
chr15_-_55563072 0.08 ENST00000567380.1
ENST00000565972.1
ENST00000569493.1
RAB27A
RAB27A, member RAS oncogene family
chr1_-_217250231 0.08 ENST00000493748.1
ENST00000463665.1
ESRRG
estrogen-related receptor gamma
chr22_-_36236265 0.08 ENST00000414461.2
ENST00000416721.2
ENST00000449924.2
ENST00000262829.7
ENST00000397305.3
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr3_-_28390581 0.08 ENST00000479665.1
AZI2
5-azacytidine induced 2
chr9_+_27109133 0.08 ENST00000519097.1
ENST00000380036.4
TEK
TEK tyrosine kinase, endothelial
chr10_+_74653330 0.08 ENST00000334011.5
OIT3
oncoprotein induced transcript 3
chr12_-_102591604 0.08 ENST00000329406.4
PMCH
pro-melanin-concentrating hormone
chr10_+_111967345 0.08 ENST00000332674.5
ENST00000453116.1
MXI1
MAX interactor 1, dimerization protein
chr1_+_33722080 0.08 ENST00000483388.1
ENST00000539719.1
ZNF362
zinc finger protein 362
chr14_+_91580357 0.07 ENST00000298858.4
ENST00000521081.1
ENST00000520328.1
ENST00000256324.10
ENST00000524232.1
ENST00000522170.1
ENST00000519950.1
ENST00000523879.1
ENST00000521077.2
ENST00000518665.2
C14orf159
chromosome 14 open reading frame 159
chr2_+_27665232 0.07 ENST00000543753.1
ENST00000288873.3
KRTCAP3
keratinocyte associated protein 3
chr1_+_164529004 0.07 ENST00000559240.1
ENST00000367897.1
ENST00000540236.1
ENST00000401534.1
PBX1
pre-B-cell leukemia homeobox 1
chr6_-_32557610 0.07 ENST00000360004.5
HLA-DRB1
major histocompatibility complex, class II, DR beta 1
chr16_-_4852915 0.07 ENST00000322048.7
ROGDI
rogdi homolog (Drosophila)
chr13_-_39564993 0.07 ENST00000423210.1
STOML3
stomatin (EPB72)-like 3
chr10_+_11207438 0.07 ENST00000609692.1
ENST00000354897.3
CELF2
CUGBP, Elav-like family member 2
chr1_+_147374915 0.07 ENST00000240986.4
GJA8
gap junction protein, alpha 8, 50kDa
chr1_+_43855560 0.07 ENST00000562955.1
SZT2
seizure threshold 2 homolog (mouse)
chr6_+_139094657 0.07 ENST00000332797.6
CCDC28A
coiled-coil domain containing 28A
chr8_+_110346546 0.06 ENST00000521662.1
ENST00000521688.1
ENST00000520147.1
ENY2
enhancer of yellow 2 homolog (Drosophila)
chr3_+_69812701 0.06 ENST00000472437.1
MITF
microphthalmia-associated transcription factor
chr7_+_142880512 0.06 ENST00000446620.1
TAS2R39
taste receptor, type 2, member 39
chr6_-_87804815 0.06 ENST00000369582.2
CGA
glycoprotein hormones, alpha polypeptide
chr6_-_31651817 0.06 ENST00000375863.3
ENST00000375860.2
LY6G5C
lymphocyte antigen 6 complex, locus G5C
chr7_-_92855762 0.06 ENST00000453812.2
ENST00000394468.2
HEPACAM2
HEPACAM family member 2

Network of associatons between targets according to the STRING database.

First level regulatory network of SRY

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.3 2.3 GO:0097338 response to clozapine(GO:0097338)
0.3 3.6 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 1.3 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.2 0.5 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.2 1.1 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.1 0.6 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 0.6 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 0.7 GO:0034670 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.1 0.3 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 0.5 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.4 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 0.4 GO:1990822 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.1 0.2 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.1 0.2 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.1 0.3 GO:0000255 allantoin metabolic process(GO:0000255)
0.1 0.9 GO:0006527 arginine catabolic process(GO:0006527) negative regulation of cellular response to hypoxia(GO:1900038)
0.1 0.4 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.4 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.1 0.4 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.3 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.2 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.0 1.2 GO:0072189 ureter development(GO:0072189)
0.0 0.3 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.2 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 1.1 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.4 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.1 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.8 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.2 GO:0009597 detection of virus(GO:0009597)
0.0 0.1 GO:0042109 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0 0.2 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.7 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.0 1.0 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.1 GO:0070417 cellular response to cold(GO:0070417)
0.0 0.2 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.3 GO:1904896 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.1 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.0 0.3 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 2.2 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.4 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841)
0.0 1.0 GO:0006536 glutamate metabolic process(GO:0006536)
0.0 0.1 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.1 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 0.5 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.0 0.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.3 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.4 GO:0003416 endochondral bone growth(GO:0003416)
0.0 0.1 GO:0002399 MHC class II protein complex assembly(GO:0002399)
0.0 0.2 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.1 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.1 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.4 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.0 0.2 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.5 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.0 0.3 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.6 GO:0071953 elastic fiber(GO:0071953)
0.1 0.6 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.1 2.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.7 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.1 1.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 1.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 0.9 GO:0030478 actin cap(GO:0030478)
0.1 0.3 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 0.2 GO:0033186 CAF-1 complex(GO:0033186)
0.0 1.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0 0.3 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 1.2 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.2 1.0 GO:0047820 D-glutamate cyclase activity(GO:0047820)
0.1 1.9 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.9 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 2.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.5 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.7 GO:1990763 arrestin family protein binding(GO:1990763)
0.1 0.6 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 1.1 GO:0015278 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.2 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.8 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.7 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.9 GO:0070410 co-SMAD binding(GO:0070410)
0.0 1.0 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.4 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.9 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.2 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.8 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.2 GO:0050815 phosphoserine binding(GO:0050815)
0.0 1.5 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.3 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.2 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.2 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 3.1 GO:0005178 integrin binding(GO:0005178)
0.0 0.1 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.3 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.0 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.3 GO:0031489 myosin V binding(GO:0031489)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.8 PID IL3 PATHWAY IL3-mediated signaling events
0.0 2.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 2.6 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.3 PID E2F PATHWAY E2F transcription factor network
0.0 0.4 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.0 PID REG GR PATHWAY Glucocorticoid receptor regulatory network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.9 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 1.3 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 1.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.3 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.7 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.6 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.6 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.5 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.5 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.1 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.4 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions