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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for STAT5A

Z-value: 1.04

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Transcription factors associated with STAT5A

Gene Symbol Gene ID Gene Info
ENSG00000126561.12 signal transducer and activator of transcription 5A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
STAT5Ahg19_v2_chr17_+_40440481_404405610.717.0e-05Click!

Activity profile of STAT5A motif

Sorted Z-values of STAT5A motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_152214098 3.78 ENST00000243347.3
tumor necrosis factor, alpha-induced protein 6
chr11_-_102668879 3.57 ENST00000315274.6
matrix metallopeptidase 1 (interstitial collagenase)
chr10_-_49812997 3.19 ENST00000417912.2
Rho GTPase activating protein 22
chr19_+_10381769 3.04 ENST00000423829.2
ENST00000588645.1
intercellular adhesion molecule 1
chr10_-_6019552 2.85 ENST00000379977.3
ENST00000397251.3
ENST00000397248.2
interleukin 15 receptor, alpha
chr15_+_67458357 2.84 ENST00000537194.2
SMAD family member 3
chr6_-_32820529 2.69 ENST00000425148.2
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr1_-_153521714 2.66 ENST00000368713.3
S100 calcium binding protein A3
chr4_+_142558078 2.65 ENST00000529613.1
interleukin 15
chr4_+_142557771 2.61 ENST00000514653.1
interleukin 15
chr3_+_122399444 2.56 ENST00000474629.2
poly (ADP-ribose) polymerase family, member 14
chr2_+_102972363 2.54 ENST00000409599.1
interleukin 18 receptor 1
chr15_+_67430339 2.38 ENST00000439724.3
SMAD family member 3
chr13_-_43566301 2.33 ENST00000398762.3
ENST00000313640.7
ENST00000313624.7
epithelial stromal interaction 1 (breast)
chr1_-_153521597 2.32 ENST00000368712.1
S100 calcium binding protein A3
chr10_-_49813090 2.29 ENST00000249601.4
Rho GTPase activating protein 22
chr1_-_8000872 2.28 ENST00000377507.3
tumor necrosis factor receptor superfamily, member 9
chr4_-_76957214 2.25 ENST00000306621.3
chemokine (C-X-C motif) ligand 11
chr1_-_41328018 2.06 ENST00000372638.2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
chr21_-_45660723 2.03 ENST00000344330.4
ENST00000407780.3
ENST00000400379.3
inducible T-cell co-stimulator ligand
chr12_+_102271129 1.99 ENST00000258534.8
DNA-damage regulated autophagy modulator 1
chr1_-_173020056 1.91 ENST00000239468.2
ENST00000404377.3
tumor necrosis factor (ligand) superfamily, member 18
chr8_+_86157699 1.80 ENST00000321764.3
carbonic anhydrase XIII
chr17_+_77021702 1.73 ENST00000392445.2
ENST00000354124.3
C1q and tumor necrosis factor related protein 1
chr21_+_42792442 1.72 ENST00000398600.2
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
chr4_-_120550146 1.69 ENST00000354960.3
phosphodiesterase 5A, cGMP-specific
chr11_+_69455855 1.64 ENST00000227507.2
ENST00000536559.1
cyclin D1
chr17_+_41158742 1.63 ENST00000415816.2
ENST00000438323.2
interferon-induced protein 35
chr12_+_21207503 1.63 ENST00000545916.1
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr7_+_55177416 1.59 ENST00000450046.1
ENST00000454757.2
epidermal growth factor receptor
chr1_-_89488510 1.56 ENST00000564665.1
ENST00000370481.4
guanylate binding protein 3
chr17_+_40440481 1.50 ENST00000590726.2
ENST00000452307.2
ENST00000444283.1
ENST00000588868.1
signal transducer and activator of transcription 5A
chr19_+_18284477 1.49 ENST00000407280.3
interferon, gamma-inducible protein 30
chr21_+_26934165 1.44 ENST00000456917.1
MIR155 host gene (non-protein coding)
chr19_-_55672037 1.41 ENST00000588076.1
dynein, axonemal, assembly factor 3
chr6_+_4706368 1.36 ENST00000328908.5
chromodomain protein, Y-like
chr10_-_6019455 1.35 ENST00000530685.1
ENST00000397255.3
ENST00000379971.1
ENST00000528354.1
ENST00000397250.2
ENST00000429135.2
interleukin 15 receptor, alpha
chr3_-_79816965 1.31 ENST00000464233.1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr16_-_75590114 1.30 ENST00000568377.1
ENST00000565067.1
ENST00000258173.6
transmembrane protein 231
chr17_-_33864772 1.26 ENST00000361112.4
schlafen family member 12-like
chr19_+_57106647 1.26 ENST00000328070.6
zinc finger protein 71
chr3_-_123512688 1.24 ENST00000475616.1
myosin light chain kinase
chr1_+_17906970 1.24 ENST00000375415.1
Rho guanine nucleotide exchange factor (GEF) 10-like
chr22_+_31644388 1.24 ENST00000333611.4
ENST00000340552.4
LIM domain kinase 2
chr8_+_23386305 1.22 ENST00000519973.1
solute carrier family 25 (mitochondrial iron transporter), member 37
chr5_-_13944652 1.22 ENST00000265104.4
dynein, axonemal, heavy chain 5
chr22_+_31608219 1.20 ENST00000406516.1
ENST00000444929.2
ENST00000331728.4
LIM domain kinase 2
chr19_+_10197463 1.20 ENST00000590378.1
ENST00000397881.3
chromosome 19 open reading frame 66
chr2_+_32853093 1.18 ENST00000448773.1
ENST00000317907.4
tetratricopeptide repeat domain 27
chr5_+_127419449 1.16 ENST00000262461.2
ENST00000343225.4
solute carrier family 12 (sodium/potassium/chloride transporter), member 2
chr18_+_55816546 1.13 ENST00000435432.2
ENST00000357895.5
ENST00000586263.1
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr11_-_105892937 1.12 ENST00000301919.4
ENST00000534458.1
ENST00000530108.1
ENST00000530788.1
Myb/SANT-like DNA-binding domain containing 4 with coiled-coils
chr10_+_115438920 1.11 ENST00000429617.1
ENST00000369331.4
caspase 7, apoptosis-related cysteine peptidase
chr16_-_11681316 1.09 ENST00000571688.1
lipopolysaccharide-induced TNF factor
chr1_-_144994840 1.08 ENST00000369351.3
ENST00000369349.3
phosphodiesterase 4D interacting protein
chr14_+_22538811 1.06 ENST00000390450.3
T cell receptor alpha variable 22
chr7_+_6144514 1.06 ENST00000306177.5
ENST00000465073.2
ubiquitin specific peptidase 42
chr16_+_50730910 1.05 ENST00000300589.2
nucleotide-binding oligomerization domain containing 2
chr12_+_133657461 1.03 ENST00000412146.2
ENST00000544426.1
ENST00000440984.2
ENST00000319849.3
ENST00000440550.2
zinc finger protein 140
chr7_-_108096822 1.02 ENST00000379028.3
ENST00000413765.2
ENST00000379022.4
neuronal cell adhesion molecule
chr10_+_115439282 1.02 ENST00000369321.2
ENST00000345633.4
caspase 7, apoptosis-related cysteine peptidase
chr19_+_42724423 1.01 ENST00000301215.3
ENST00000597945.1
zinc finger protein 526
chr16_-_75498308 1.01 ENST00000569540.1
transmembrane protein 170A
chr17_-_34207295 1.00 ENST00000463941.1
ENST00000293272.3
chemokine (C-C motif) ligand 5
chr1_-_55230165 1.00 ENST00000371279.3
prolyl-tRNA synthetase 2, mitochondrial (putative)
chr10_+_115439630 0.99 ENST00000369318.3
caspase 7, apoptosis-related cysteine peptidase
chr15_+_63414017 0.97 ENST00000413507.2
lactamase, beta
chr21_+_34602680 0.97 ENST00000447980.1
interferon (alpha, beta and omega) receptor 2
chr16_+_57653854 0.96 ENST00000568908.1
ENST00000568909.1
ENST00000566778.1
ENST00000561988.1
G protein-coupled receptor 56
chr10_+_115439699 0.95 ENST00000369315.1
caspase 7, apoptosis-related cysteine peptidase
chr10_+_6625605 0.95 ENST00000414894.1
ENST00000449648.1
PRKCQ antisense RNA 1
chr17_+_77030267 0.94 ENST00000581774.1
C1q and tumor necrosis factor related protein 1
chr12_-_117318788 0.94 ENST00000550505.1
harakiri, BCL2 interacting protein (contains only BH3 domain)
chr6_+_116692102 0.91 ENST00000359564.2
dermatan sulfate epimerase
chr15_+_63414760 0.90 ENST00000557972.1
lactamase, beta
chr8_+_38586068 0.90 ENST00000443286.2
ENST00000520340.1
ENST00000518415.1
transforming, acidic coiled-coil containing protein 1
chr4_-_185395672 0.90 ENST00000393593.3
interferon regulatory factor 2
chr6_-_137539651 0.88 ENST00000543628.1
interferon gamma receptor 1
chr6_+_108487245 0.88 ENST00000368986.4
nuclear receptor subfamily 2, group E, member 1
chr18_-_44561988 0.88 ENST00000332567.4
transcription elongation factor B polypeptide 3B (elongin A2)
chr1_-_145075847 0.87 ENST00000530740.1
ENST00000369359.4
phosphodiesterase 4D interacting protein
chr6_-_30654977 0.86 ENST00000399199.3
protein phosphatase 1, regulatory subunit 18
chr8_-_12612962 0.86 ENST00000398246.3
LON peptidase N-terminal domain and ring finger 1
chrX_+_1455478 0.86 ENST00000331035.4
interleukin 3 receptor, alpha (low affinity)
chr7_-_108096765 0.84 ENST00000379024.4
ENST00000351718.4
neuronal cell adhesion molecule
chr5_+_149887672 0.83 ENST00000261797.6
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr9_+_98534605 0.81 ENST00000600140.1
Protein LOC100506667; Putative uncharacterized protein DKFZp434H0512
chr22_-_50523760 0.81 ENST00000395876.2
megalencephalic leukoencephalopathy with subcortical cysts 1
chr12_+_20968608 0.81 ENST00000381541.3
ENST00000540229.1
ENST00000553473.1
ENST00000554957.1
Putative solute carrier organic anion transporter family member 1B7; Uncharacterized protein
solute carrier organic anion transporter family, member 1B3
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr2_+_201994569 0.78 ENST00000457277.1
CASP8 and FADD-like apoptosis regulator
chr14_-_91710852 0.76 ENST00000535815.1
ENST00000529102.1
G protein-coupled receptor 68
chrX_+_149861836 0.76 ENST00000542156.1
ENST00000370390.3
ENST00000490316.2
ENST00000445323.2
ENST00000544228.1
ENST00000451863.2
myotubularin related protein 1
chr7_+_7606497 0.76 ENST00000340080.4
ENST00000405785.1
ENST00000433635.1
missing oocyte, meiosis regulator, homolog (Drosophila)
chr15_-_70387120 0.76 ENST00000539550.1
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr10_+_90750378 0.76 ENST00000355740.2
ENST00000352159.4
Fas cell surface death receptor
chrX_-_11445856 0.75 ENST00000380736.1
Rho GTPase activating protein 6
chr18_+_61637159 0.74 ENST00000397985.2
ENST00000353706.2
ENST00000542677.1
ENST00000397988.3
ENST00000448851.1
serpin peptidase inhibitor, clade B (ovalbumin), member 8
chr16_+_3313791 0.72 ENST00000538765.1
zinc finger protein 263
chr1_-_201438282 0.72 ENST00000367311.3
ENST00000367309.1
pleckstrin homology-like domain, family A, member 3
chr14_-_51135036 0.72 ENST00000324679.4
salvador homolog 1 (Drosophila)
chr22_-_32651326 0.71 ENST00000266086.4
solute carrier family 5 (glucose activated ion channel), member 4
chr22_-_31503490 0.71 ENST00000400299.2
Selenoprotein M
chr19_+_44081344 0.69 ENST00000599207.1
phospholipase A2 inhibitor and LY6/PLAUR domain containing
chr18_-_74839891 0.68 ENST00000581878.1
myelin basic protein
chr12_+_10658489 0.68 ENST00000538173.1
Putative eukaryotic translation initiation factor 2 subunit 3-like protein
chr20_+_58251716 0.68 ENST00000355648.4
phosphatase and actin regulator 3
chr8_+_27629459 0.66 ENST00000523566.1
establishment of sister chromatid cohesion N-acetyltransferase 2
chr15_-_38856836 0.65 ENST00000450598.2
ENST00000559830.1
ENST00000558164.1
ENST00000310803.5
RAS guanyl releasing protein 1 (calcium and DAG-regulated)
chr12_-_10151773 0.65 ENST00000298527.6
ENST00000348658.4
C-type lectin domain family 1, member B
chr21_+_34602200 0.65 ENST00000382264.3
ENST00000382241.3
ENST00000404220.3
ENST00000342136.4
interferon (alpha, beta and omega) receptor 2
chr21_+_34602377 0.64 ENST00000342101.3
ENST00000413881.1
ENST00000443073.1
interferon (alpha, beta and omega) receptor 2
chr5_+_121297650 0.64 ENST00000339397.4
serum response factor binding protein 1
chr7_+_117120017 0.63 ENST00000003084.6
ENST00000454343.1
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
chr1_-_144994909 0.63 ENST00000369347.4
ENST00000369354.3
phosphodiesterase 4D interacting protein
chr12_+_72058130 0.63 ENST00000547843.1
THAP domain containing, apoptosis associated protein 2
chr6_-_11807277 0.63 ENST00000379415.2
androgen-dependent TFPI-regulating protein
chr19_+_35168547 0.63 ENST00000502743.1
ENST00000509528.1
ENST00000506901.1
zinc finger protein 302
chr2_-_208634287 0.62 ENST00000295417.3
frizzled family receptor 5
chr14_-_24898731 0.62 ENST00000267406.6
cerebellin 3 precursor
chr4_+_169418195 0.60 ENST00000261509.6
ENST00000335742.7
palladin, cytoskeletal associated protein
chr12_+_10658201 0.60 ENST00000322446.3
Putative eukaryotic translation initiation factor 2 subunit 3-like protein
chr22_+_21128167 0.59 ENST00000215727.5
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr1_+_144146808 0.59 ENST00000369190.5
ENST00000412624.2
ENST00000369365.3
neuroblastoma breakpoint family, member 8
chr6_-_159240415 0.59 ENST00000367075.3
ezrin
chr9_+_103189660 0.59 ENST00000374886.3
Myb/SANT-like DNA-binding domain containing 3
chr11_-_104827425 0.57 ENST00000393150.3
caspase 4, apoptosis-related cysteine peptidase
chr2_-_85636928 0.57 ENST00000449030.1
capping protein (actin filament), gelsolin-like
chr2_-_28113217 0.57 ENST00000444339.2
ribokinase
chr22_-_18507279 0.57 ENST00000441493.2
ENST00000444520.1
ENST00000207726.7
ENST00000429452.1
microtubule associated monooxygenase, calponin and LIM domain containing 3
chr6_+_108977520 0.57 ENST00000540898.1
forkhead box O3
chr5_-_59783882 0.56 ENST00000505507.2
ENST00000502484.2
phosphodiesterase 4D, cAMP-specific
chr15_-_72767490 0.56 ENST00000565181.1
RP11-1007O24.3
chr1_-_160924589 0.56 ENST00000368029.3
intelectin 2
chr6_+_144471643 0.56 ENST00000367568.4
syntaxin 11
chr10_+_90750493 0.55 ENST00000357339.2
ENST00000355279.2
Fas cell surface death receptor
chr10_+_114043493 0.55 ENST00000369422.3
tectorin beta
chr21_-_37451680 0.54 ENST00000399201.1
SET domain containing 4
chr7_+_112063192 0.53 ENST00000005558.4
interferon-related developmental regulator 1
chr1_+_168756151 0.53 ENST00000420691.1
long intergenic non-protein coding RNA 626
chr2_+_108994466 0.53 ENST00000272452.2
sulfotransferase family, cytosolic, 1C, member 4
chr22_+_37257015 0.53 ENST00000447071.1
ENST00000248899.6
ENST00000397147.4
neutrophil cytosolic factor 4, 40kDa
chr20_-_43280361 0.53 ENST00000372874.4
adenosine deaminase
chr3_+_149191723 0.52 ENST00000305354.4
transmembrane 4 L six family member 4
chr11_-_133715394 0.52 ENST00000299140.3
ENST00000532889.1
spermatogenesis associated 19
chr22_-_45636650 0.52 ENST00000336156.5
KIAA0930
chr9_-_94877658 0.52 ENST00000262554.2
ENST00000337841.4
serine palmitoyltransferase, long chain base subunit 1
chr22_-_47882857 0.51 ENST00000405369.3
Novel protein; Uncharacterized protein
chr8_-_128960591 0.51 ENST00000539634.1
transmembrane protein 75
chr11_-_59383617 0.51 ENST00000263847.1
oxysterol binding protein
chr12_+_22199108 0.51 ENST00000229329.2
cytidine monophosphate N-acetylneuraminic acid synthetase
chr3_+_151531810 0.51 ENST00000232892.7
arylacetamide deacetylase
chr7_-_26578407 0.51 ENST00000242109.3
KIAA0087
chr12_+_22778291 0.50 ENST00000545979.1
ethanolamine kinase 1
chr9_+_124922171 0.50 ENST00000373764.3
ENST00000536616.1
MORN repeat containing 5
chr2_-_152146385 0.50 ENST00000414946.1
ENST00000243346.5
N-myc (and STAT) interactor
chr19_-_58090240 0.50 ENST00000196489.3
zinc finger protein 416
chr11_-_104905840 0.50 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
caspase 1, apoptosis-related cysteine peptidase
chr11_+_58912240 0.50 ENST00000527629.1
ENST00000361723.3
ENST00000531408.1
family with sequence similarity 111, member A
chr12_-_69080590 0.49 ENST00000433116.2
ENST00000500695.2
RP11-637A17.2
chrX_+_122993657 0.49 ENST00000434753.3
ENST00000430625.1
X-linked inhibitor of apoptosis
chr16_+_56672571 0.49 ENST00000290705.8
metallothionein 1A
chr2_+_108994633 0.49 ENST00000409309.3
sulfotransferase family, cytosolic, 1C, member 4
chr10_-_27443294 0.48 ENST00000396296.3
ENST00000375972.3
ENST00000376016.3
ENST00000491542.2
YME1-like 1 ATPase
chr11_+_117070904 0.48 ENST00000529792.1
transgelin
chr15_+_66797627 0.48 ENST00000565627.1
ENST00000564179.1
zwilch kinetochore protein
chr21_+_34697209 0.48 ENST00000270139.3
interferon (alpha, beta and omega) receptor 1
chr19_-_6737241 0.48 ENST00000430424.4
ENST00000597298.1
G protein-coupled receptor 108
chr1_-_144995002 0.48 ENST00000369356.4
phosphodiesterase 4D interacting protein
chr12_-_4758159 0.48 ENST00000545990.2
A kinase (PRKA) anchor protein 3
chr3_-_107941209 0.47 ENST00000492106.1
intraflagellar transport 57 homolog (Chlamydomonas)
chr10_-_27443155 0.47 ENST00000427324.1
ENST00000326799.3
YME1-like 1 ATPase
chr1_+_114471809 0.47 ENST00000426820.2
homeodomain interacting protein kinase 1
chrX_+_18725758 0.47 ENST00000472826.1
ENST00000544635.1
ENST00000496075.2
protein phosphatase, EF-hand calcium binding domain 1
chr6_-_33548006 0.46 ENST00000374467.3
BCL2-antagonist/killer 1
chr1_-_100643765 0.46 ENST00000370137.1
ENST00000370138.1
ENST00000342895.3
leucine rich repeat containing 39
chr17_-_15502111 0.46 ENST00000354433.3
CMT1A duplicated region transcript 1
chr11_-_9025541 0.46 ENST00000525100.1
ENST00000309166.3
ENST00000531090.1
nuclear receptor interacting protein 3
chr1_-_153283194 0.45 ENST00000290722.1
peptidoglycan recognition protein 3
chr6_-_33547975 0.45 ENST00000442998.2
ENST00000360661.5
BCL2-antagonist/killer 1
chr2_-_69098566 0.45 ENST00000295379.1
bone morphogenetic protein 10
chr9_-_136203235 0.45 ENST00000372022.4
surfeit 6
chr11_-_117695449 0.45 ENST00000292079.2
FXYD domain containing ion transport regulator 2
chr1_-_23342340 0.44 ENST00000566855.1
chromosome 1 open reading frame 234
chr15_+_101142722 0.44 ENST00000332783.7
ENST00000558747.1
ENST00000343276.4
ankyrin repeat and SOCS box containing 7
chr5_+_8457793 0.44 ENST00000606459.1
MIR4458 host gene (non-protein coding)
chr10_+_82298088 0.44 ENST00000470604.2
SH2 domain containing 4B
chr20_+_61436146 0.44 ENST00000290291.6
opioid growth factor receptor
chr16_-_21663919 0.44 ENST00000569602.1
immunoglobulin superfamily, member 6
chr12_+_70132632 0.44 ENST00000378815.6
ENST00000483530.2
ENST00000325555.9
RAB3A interacting protein
chr19_+_44507091 0.44 ENST00000429154.2
ENST00000585632.1
zinc finger protein 230
chr1_-_89357179 0.43 ENST00000448623.1
ENST00000418217.1
ENST00000370500.5
general transcription factor IIB
chr15_+_66797455 0.43 ENST00000446801.2
zwilch kinetochore protein
chr1_-_144995074 0.43 ENST00000534536.1
phosphodiesterase 4D interacting protein
chr3_+_111260980 0.43 ENST00000438817.2
CD96 molecule
chr6_+_7541808 0.43 ENST00000379802.3
desmoplakin
chr7_+_134464376 0.43 ENST00000454108.1
ENST00000361675.2
caldesmon 1
chr4_+_155484155 0.43 ENST00000509493.1
fibrinogen beta chain
chr14_+_22320634 0.43 ENST00000390435.1
T cell receptor alpha variable 8-3
chr11_-_62609281 0.43 ENST00000525239.1
ENST00000538098.2
WD repeat domain 74
chr1_+_171454639 0.42 ENST00000392078.3
ENST00000426496.2
proline-rich coiled-coil 2C

Network of associatons between targets according to the STRING database.

First level regulatory network of STAT5A

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.3 GO:0045062 extrathymic T cell selection(GO:0045062)
1.0 5.2 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.8 3.0 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.7 2.7 GO:0046967 cytosol to ER transport(GO:0046967)
0.5 4.1 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.5 1.9 GO:2000329 negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.4 1.3 GO:0021836 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.4 2.1 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.4 1.2 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.4 1.6 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.4 1.2 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.4 1.5 GO:0000255 allantoin metabolic process(GO:0000255)
0.4 2.1 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183)
0.3 2.7 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.3 1.0 GO:0006433 prolyl-tRNA aminoacylation(GO:0006433)
0.3 1.0 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.3 0.9 GO:0002352 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.3 0.9 GO:0006154 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.2 2.5 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.2 1.9 GO:0070141 response to UV-A(GO:0070141)
0.2 1.7 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.2 0.7 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.2 1.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.2 1.3 GO:0036337 Fas signaling pathway(GO:0036337)
0.2 2.3 GO:0035655 interleukin-18-mediated signaling pathway(GO:0035655)
0.2 0.6 GO:0060061 Spemann organizer formation(GO:0060061)
0.2 0.6 GO:0044278 cell wall disruption in other organism(GO:0044278)
0.2 1.4 GO:0008218 bioluminescence(GO:0008218)
0.2 0.4 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.2 0.6 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.2 0.5 GO:0007518 myoblast fate determination(GO:0007518)
0.2 0.9 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.2 0.5 GO:0006667 sphinganine metabolic process(GO:0006667)
0.2 1.9 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.2 0.8 GO:0019303 D-ribose catabolic process(GO:0019303)
0.2 0.5 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.2 1.8 GO:0003374 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.2 0.8 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.2 0.5 GO:0032826 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) positive regulation of cytolysis in other organism(GO:0051714)
0.1 0.4 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.1 0.9 GO:0036016 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.1 0.6 GO:0002727 natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
0.1 1.0 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.1 0.4 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.1 0.4 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.1 3.8 GO:0030728 ovulation(GO:0030728)
0.1 0.4 GO:0061091 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.1 0.5 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.1 0.4 GO:0038188 cholecystokinin signaling pathway(GO:0038188)
0.1 0.5 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.1 1.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.6 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.1 0.7 GO:1904207 maintenance of blood-brain barrier(GO:0035633) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.1 0.4 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.1 0.7 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.3 GO:0033025 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.1 0.7 GO:0032252 secretory granule localization(GO:0032252)
0.1 0.3 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.1 0.5 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.1 1.3 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.1 0.9 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.4 GO:0046104 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.1 0.5 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.1 2.3 GO:0006972 hyperosmotic response(GO:0006972)
0.1 0.8 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.1 0.4 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.1 0.3 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 3.4 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.1 0.3 GO:0006624 vacuolar protein processing(GO:0006624)
0.1 0.4 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.1 0.3 GO:1900155 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.1 0.3 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.1 0.7 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 2.4 GO:0035455 response to interferon-alpha(GO:0035455)
0.1 0.3 GO:0015785 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.1 0.3 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.1 0.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.2 GO:0034136 negative regulation of toll-like receptor 2 signaling pathway(GO:0034136)
0.1 0.6 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 0.2 GO:1905026 positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903762) positive regulation of ventricular cardiac muscle cell action potential(GO:1903947) positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905026) positive regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905033)
0.1 1.2 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.1 0.8 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.8 GO:1901740 negative regulation of myoblast fusion(GO:1901740) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 0.4 GO:0015722 canalicular bile acid transport(GO:0015722)
0.1 2.6 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.1 0.2 GO:0046968 peptide antigen transport(GO:0046968)
0.1 0.2 GO:1904387 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.1 0.1 GO:0003099 positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.1 0.2 GO:1990258 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.1 0.2 GO:0042369 vitamin D catabolic process(GO:0042369)
0.1 0.3 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.1 0.3 GO:0007343 egg activation(GO:0007343)
0.1 0.7 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.1 0.9 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.6 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059) lens induction in camera-type eye(GO:0060235)
0.1 0.6 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1 0.4 GO:0001705 ectoderm formation(GO:0001705) ectodermal cell fate commitment(GO:0001712)
0.1 0.6 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.1 0.3 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.1 0.3 GO:1901674 histone H3-K27 acetylation(GO:0043974) leukemia inhibitory factor signaling pathway(GO:0048861) regulation of histone H3-K27 acetylation(GO:1901674)
0.1 0.1 GO:0071109 superior temporal gyrus development(GO:0071109)
0.1 0.2 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.1 0.2 GO:1990637 response to prolactin(GO:1990637)
0.1 0.2 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.1 0.4 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 1.2 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.1 0.1 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
0.1 0.3 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.1 0.5 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1 0.3 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.1 0.3 GO:0015808 L-alanine transport(GO:0015808) L-cystine transport(GO:0015811)
0.1 0.7 GO:0015816 glycine transport(GO:0015816)
0.1 0.3 GO:0002767 immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.1 0.2 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.1 0.2 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.1 0.2 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.1 0.3 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.1 0.4 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 0.3 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.1 0.8 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.1 0.3 GO:0035803 egg coat formation(GO:0035803)
0.1 0.1 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.1 GO:0097254 renal tubular secretion(GO:0097254)
0.0 0.1 GO:1901053 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.0 0.9 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.2 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.2 GO:0010958 regulation of amino acid import(GO:0010958)
0.0 0.6 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.3 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.0 2.0 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.0 0.3 GO:0071799 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0 0.6 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.4 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.5 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.1 GO:0071315 cellular response to morphine(GO:0071315) cellular response to isoquinoline alkaloid(GO:0071317)
0.0 1.1 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.3 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.2 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.1 GO:0006788 heme oxidation(GO:0006788)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.2 GO:1904798 positive regulation of core promoter binding(GO:1904798)
0.0 0.9 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.2 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.1 GO:0060557 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.0 0.1 GO:0071442 regulation of histone H3-K14 acetylation(GO:0071440) positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.2 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.9 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.2 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.0 0.4 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.0 0.8 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0043128 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.0 0.5 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.1 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0 0.1 GO:0048769 sarcomerogenesis(GO:0048769)
0.0 1.8 GO:0045026 plasma membrane fusion(GO:0045026)
0.0 0.2 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.3 GO:0006561 proline biosynthetic process(GO:0006561)
0.0 0.6 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.3 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.4 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 0.2 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.1 GO:0097068 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.0 0.3 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0 0.1 GO:0009386 translational attenuation(GO:0009386)
0.0 0.4 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.6 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.0 0.4 GO:0060263 regulation of respiratory burst(GO:0060263)
0.0 2.0 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.4 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.2 GO:0070269 pyroptosis(GO:0070269)
0.0 0.2 GO:0002326 B cell lineage commitment(GO:0002326) immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.2 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.2 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0 1.0 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 0.1 GO:0042495 detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.1 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.0 0.5 GO:0044117 growth of symbiont in host(GO:0044117) regulation of growth of symbiont in host(GO:0044126)
0.0 0.2 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.2 GO:0061042 vascular wound healing(GO:0061042)
0.0 0.4 GO:0032930 positive regulation of superoxide anion generation(GO:0032930)
0.0 0.2 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.0 0.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.1 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.3 GO:0043313 regulation of neutrophil degranulation(GO:0043313)
0.0 0.1 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.0 0.3 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.3 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.1 GO:0072144 glomerular mesangial cell differentiation(GO:0072008) glomerular mesangial cell development(GO:0072144)
0.0 0.2 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.0 0.3 GO:0016198 axon choice point recognition(GO:0016198)
0.0 0.3 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.7 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.4 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.2 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 0.8 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.1 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.0 0.1 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.1 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.1 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.3 GO:0045779 negative regulation of bone resorption(GO:0045779)
0.0 0.1 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.4 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.9 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.2 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.3 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.3 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.8 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.0 0.7 GO:0030220 platelet formation(GO:0030220)
0.0 0.6 GO:0002715 regulation of natural killer cell mediated immunity(GO:0002715)
0.0 0.1 GO:0071504 cellular response to heparin(GO:0071504)
0.0 0.2 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.7 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.5 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.4 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.3 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.2 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.6 GO:0097186 amelogenesis(GO:0097186)
0.0 0.2 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.0 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.0 0.2 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.1 GO:1902548 negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548)
0.0 0.2 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.8 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.8 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.3 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.0 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.1 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.0 0.2 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 1.3 GO:0042274 ribosomal small subunit biogenesis(GO:0042274)
0.0 0.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.1 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.0 0.2 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.3 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.3 GO:0043970 histone H3-K9 acetylation(GO:0043970)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.6 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.3 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.2 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.0 0.0 GO:2000619 negative regulation of histone H4-K16 acetylation(GO:2000619)
0.0 0.0 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534) glutamate secretion, neurotransmission(GO:0061535)
0.0 0.2 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.8 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.4 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.2 GO:0006702 androgen biosynthetic process(GO:0006702)
0.0 0.4 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.4 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.1 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.0 0.5 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.2 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.1 GO:0072592 oxygen metabolic process(GO:0072592)
0.0 0.1 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.2 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.5 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.0 0.0 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0 0.3 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.0 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.1 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.0 0.0 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) negative regulation of receptor catabolic process(GO:2000645)
0.0 0.5 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.3 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.0 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.3 GO:0046688 response to copper ion(GO:0046688)
0.0 0.2 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.3 GO:0019731 antibacterial humoral response(GO:0019731)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 5.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.5 1.6 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.4 2.7 GO:0042825 TAP complex(GO:0042825)
0.3 1.0 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.2 0.9 GO:0035339 SPOTS complex(GO:0035339)
0.2 0.9 GO:1990423 RZZ complex(GO:1990423)
0.2 1.0 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.1 1.1 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559) cytoplasmic side of late endosome membrane(GO:0098560)
0.1 1.2 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.1 0.4 GO:0034681 integrin alpha11-beta1 complex(GO:0034681)
0.1 0.6 GO:0097454 microspike(GO:0044393) Schwann cell microvillus(GO:0097454)
0.1 1.2 GO:0036157 outer dynein arm(GO:0036157)
0.1 0.3 GO:0016935 glycine-gated chloride channel complex(GO:0016935)
0.1 0.6 GO:0001652 granular component(GO:0001652)
0.1 0.3 GO:0035841 new growing cell tip(GO:0035841)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.9 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 0.3 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.1 0.2 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.1 0.2 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.1 0.3 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.1 0.3 GO:0097441 basilar dendrite(GO:0097441)
0.1 1.5 GO:0043194 axon initial segment(GO:0043194)
0.1 1.3 GO:0036038 MKS complex(GO:0036038)
0.1 0.9 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.4 GO:0043219 lateral loop(GO:0043219)
0.1 0.8 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.3 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.1 3.5 GO:0001772 immunological synapse(GO:0001772)
0.1 0.3 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 0.7 GO:0044292 dendrite terminus(GO:0044292)
0.1 0.5 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.3 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.2 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 0.3 GO:0005818 astral microtubule(GO:0000235) aster(GO:0005818)
0.0 0.2 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.2 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 4.0 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.4 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 0.1 GO:0098855 HCN channel complex(GO:0098855)
0.0 0.1 GO:0032127 dense core granule membrane(GO:0032127)
0.0 0.4 GO:0033269 internode region of axon(GO:0033269)
0.0 0.7 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.2 GO:0005606 laminin-1 complex(GO:0005606)
0.0 0.7 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.8 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.6 GO:0005916 fascia adherens(GO:0005916)
0.0 0.4 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.2 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.5 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.7 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 2.1 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.7 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.4 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 3.2 GO:0005581 collagen trimer(GO:0005581)
0.0 0.9 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.3 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.3 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.2 GO:0036128 CatSper complex(GO:0036128)
0.0 1.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0034455 t-UTP complex(GO:0034455)
0.0 0.7 GO:0030686 90S preribosome(GO:0030686)
0.0 0.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.2 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 0.2 GO:0043203 axon hillock(GO:0043203)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 1.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.2 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.6 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 1.1 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.3 GO:0046930 pore complex(GO:0046930)
0.0 0.1 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.7 GO:0030673 axolemma(GO:0030673)
0.0 2.7 GO:0005884 actin filament(GO:0005884)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.5 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.9 GO:0005771 multivesicular body(GO:0005771)
0.0 0.1 GO:0043196 varicosity(GO:0043196)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 1.1 GO:0015030 Cajal body(GO:0015030)
0.0 1.2 GO:0005901 caveola(GO:0005901)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.1 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.2 GO:0001741 XY body(GO:0001741)
0.0 0.2 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.0 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 0.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.1 GO:0000801 central element(GO:0000801)
0.0 0.1 GO:0033268 node of Ranvier(GO:0033268) paranode region of axon(GO:0033270)
0.0 0.7 GO:0031201 SNARE complex(GO:0031201)
0.0 0.4 GO:0035580 specific granule lumen(GO:0035580)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.2 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.5 2.6 GO:0004905 type I interferon receptor activity(GO:0004905)
0.4 2.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.4 2.7 GO:0046979 TAP2 binding(GO:0046979)
0.3 1.0 GO:0004827 proline-tRNA ligase activity(GO:0004827)
0.3 1.3 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.3 1.0 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.3 1.5 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.3 1.3 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.2 0.9 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.2 0.9 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.2 0.5 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.2 2.5 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.2 1.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.6 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.1 2.7 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 0.4 GO:0004797 thymidine kinase activity(GO:0004797)
0.1 4.5 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 2.2 GO:0042834 peptidoglycan binding(GO:0042834)
0.1 0.9 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.1 4.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.4 GO:0004951 cholecystokinin receptor activity(GO:0004951)
0.1 1.0 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 1.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.4 GO:0005124 scavenger receptor binding(GO:0005124)
0.1 0.6 GO:0004995 tachykinin receptor activity(GO:0004995)
0.1 0.4 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.1 0.3 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.3 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.1 1.9 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 1.5 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.1 0.5 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.6 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.1 0.4 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 2.2 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 0.3 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 1.1 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.3 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 0.3 GO:0022858 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.1 0.7 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 0.4 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 0.7 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 0.2 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.1 0.4 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.1 0.2 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.1 0.2 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.1 0.1 GO:0001855 complement component C4b binding(GO:0001855)
0.1 0.2 GO:0036009 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.1 1.2 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.1 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.1 0.4 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.1 0.4 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.1 0.3 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.1 0.2 GO:0004766 spermidine synthase activity(GO:0004766)
0.1 0.4 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.1 0.4 GO:0042835 BRE binding(GO:0042835)
0.1 0.3 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.4 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 0.7 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 2.1 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 0.2 GO:0001147 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.1 0.8 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 0.8 GO:0004985 opioid receptor activity(GO:0004985)
0.1 0.2 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.1 2.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.2 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.1 0.9 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.9 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.1 0.2 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.1 0.9 GO:0004000 adenosine deaminase activity(GO:0004000)
0.1 1.6 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.2 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.1 1.2 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 0.5 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.1 0.4 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.7 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.1 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.2 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.2 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.2 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.3 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.4 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 1.4 GO:0030553 cGMP binding(GO:0030553)
0.0 0.1 GO:0008480 sarcosine dehydrogenase activity(GO:0008480)
0.0 0.2 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.1 GO:0045518 interleukin-22 receptor binding(GO:0045518)
0.0 0.4 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.2 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.1 GO:0043337 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.0 0.1 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 0.3 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.3 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.7 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.9 GO:0051400 BH domain binding(GO:0051400)
0.0 0.2 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.3 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.2 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 1.0 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.3 GO:0035473 lipase binding(GO:0035473)
0.0 0.4 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.2 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.2 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.0 0.7 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 4.5 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 9.8 GO:0005125 cytokine activity(GO:0005125)
0.0 1.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.3 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.4 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 1.0 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.7 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.4 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 2.9 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.5 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 0.3 GO:0015288 porin activity(GO:0015288)
0.0 0.2 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.6 GO:0005549 odorant binding(GO:0005549)
0.0 0.3 GO:0032190 acrosin binding(GO:0032190)
0.0 0.1 GO:0050429 calcium-dependent phospholipase C activity(GO:0050429)
0.0 0.2 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.2 GO:0051373 FATZ binding(GO:0051373)
0.0 0.6 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.1 GO:0051431 corticotropin-releasing hormone receptor 1 binding(GO:0051430) corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.0 0.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.3 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.2 GO:0030109 HLA-B specific inhibitory MHC class I receptor activity(GO:0030109)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.1 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.3 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 1.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 3.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 3.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.3 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0050135 NAD+ nucleosidase activity(GO:0003953) NAD(P)+ nucleosidase activity(GO:0050135)
0.0 0.1 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.0 0.1 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.1 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.0 0.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0001632 leukotriene B4 receptor activity(GO:0001632)
0.0 0.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.4 GO:0005537 mannose binding(GO:0005537)
0.0 0.1 GO:0002134 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.0 0.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.2 GO:0030882 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.1 GO:0035650 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.0 0.3 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.4 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.2 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.1 GO:0010858 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.1 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.1 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.5 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.0 0.6 GO:0071949 FAD binding(GO:0071949)
0.0 0.1 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.5 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.2 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.9 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:0016972 thiol oxidase activity(GO:0016972)
0.0 0.9 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.2 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.3 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.3 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.3 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.8 GO:0050699 WW domain binding(GO:0050699)
0.0 0.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.3 GO:0043295 glutathione binding(GO:0043295)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.6 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.0 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.4 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.1 GO:0047086 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.2 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.0 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 1.0 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.4 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.8 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948)
0.0 0.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 4.6 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 2.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 5.7 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 1.6 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 3.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 2.0 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 4.0 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.9 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.9 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 16.9 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 2.2 PID RHOA PATHWAY RhoA signaling pathway
0.0 1.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.8 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.9 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.9 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 7.3 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.3 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 1.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 1.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.3 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.9 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.9 PID AURORA A PATHWAY Aurora A signaling
0.0 1.2 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.0 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.8 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.3 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 1.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.0 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.6 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.3 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.6 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.8 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.2 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.3 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 3.7 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0 0.2 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.2 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.2 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 1.7 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 3.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.9 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 5.6 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.1 2.8 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 1.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 0.9 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 1.0 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 2.9 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 1.6 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.1 1.6 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 2.0 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.3 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1 3.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 4.2 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 2.3 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 1.2 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.0 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 2.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.0 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.8 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.6 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.9 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.6 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 1.0 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.1 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.0 1.3 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.7 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.6 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 1.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.4 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.9 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.0 0.3 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.1 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 1.1 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.1 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 1.0 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.5 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.4 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.3 REACTOME OPSINS Genes involved in Opsins
0.0 0.6 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.3 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.0 0.2 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.5 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.5 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.6 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.3 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.2 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 1.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.2 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.9 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 1.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.6 REACTOME DEFENSINS Genes involved in Defensins
0.0 0.2 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 1.1 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.3 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.5 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.7 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.0 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation