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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for STAT6

Z-value: 0.61

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Transcription factors associated with STAT6

Gene Symbol Gene ID Gene Info
STAT6
ENSG00000166888.6 signal transducer and activator of transcription 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
STAT6hg19_v2_chr12_-_57505121_57505216-0.222.9e-01Click!

Activity profile of STAT6 motif

Sorted Z-values of STAT6 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_3469181 1.37 ENST00000366116.2
AL365202.1
Uncharacterized protein
chr1_+_61869748 1.24 ENST00000357977.5
NFIA
nuclear factor I/A
chr12_+_9144626 1.13 ENST00000543895.1
KLRG1
killer cell lectin-like receptor subfamily G, member 1
chr15_+_89402148 1.10 ENST00000560601.1
ACAN
aggrecan
chr4_-_186877806 0.96 ENST00000355634.5
SORBS2
sorbin and SH3 domain containing 2
chr8_+_97506033 0.83 ENST00000518385.1
SDC2
syndecan 2
chr2_+_182756915 0.82 ENST00000428267.2
SSFA2
sperm specific antigen 2
chr10_+_102106829 0.81 ENST00000370355.2
SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chrX_+_135251835 0.76 ENST00000456445.1
FHL1
four and a half LIM domains 1
chr17_+_40912764 0.76 ENST00000589683.1
ENST00000588928.1
RAMP2
receptor (G protein-coupled) activity modifying protein 2
chr3_+_141121164 0.74 ENST00000510338.1
ENST00000504673.1
ZBTB38
zinc finger and BTB domain containing 38
chr12_+_6493406 0.73 ENST00000543190.1
LTBR
lymphotoxin beta receptor (TNFR superfamily, member 3)
chrX_+_135251783 0.72 ENST00000394153.2
FHL1
four and a half LIM domains 1
chr4_-_116034979 0.63 ENST00000264363.2
NDST4
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
chr2_+_191792376 0.61 ENST00000409428.1
ENST00000409215.1
GLS
glutaminase
chr21_+_17791838 0.56 ENST00000453910.1
LINC00478
long intergenic non-protein coding RNA 478
chr17_+_7384721 0.56 ENST00000412468.2
SLC35G6
solute carrier family 35, member G6
chr9_+_90112767 0.55 ENST00000408954.3
DAPK1
death-associated protein kinase 1
chrX_+_135252050 0.55 ENST00000449474.1
ENST00000345434.3
FHL1
four and a half LIM domains 1
chr11_-_128457446 0.54 ENST00000392668.4
ETS1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
chr9_+_90112741 0.54 ENST00000469640.2
DAPK1
death-associated protein kinase 1
chr5_-_88119580 0.53 ENST00000539796.1
MEF2C
myocyte enhancer factor 2C
chr21_+_17791648 0.53 ENST00000602892.1
ENST00000418813.2
ENST00000435697.1
LINC00478
long intergenic non-protein coding RNA 478
chr9_+_90112590 0.53 ENST00000472284.1
DAPK1
death-associated protein kinase 1
chr1_-_76398077 0.51 ENST00000284142.6
ASB17
ankyrin repeat and SOCS box containing 17
chr9_+_90112117 0.48 ENST00000358077.5
DAPK1
death-associated protein kinase 1
chr1_-_68299130 0.46 ENST00000370982.3
GNG12
guanine nucleotide binding protein (G protein), gamma 12
chr14_-_23285069 0.46 ENST00000554758.1
ENST00000397528.4
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr14_+_55034599 0.46 ENST00000392067.3
ENST00000357634.3
SAMD4A
sterile alpha motif domain containing 4A
chr14_-_23285011 0.45 ENST00000397532.3
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr2_+_219745020 0.44 ENST00000258411.3
WNT10A
wingless-type MMTV integration site family, member 10A
chr2_+_173600514 0.43 ENST00000264111.6
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr2_+_173600565 0.43 ENST00000397081.3
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr4_-_110723134 0.42 ENST00000510800.1
ENST00000512148.1
CFI
complement factor I
chr12_+_6493319 0.42 ENST00000536876.1
LTBR
lymphotoxin beta receptor (TNFR superfamily, member 3)
chr1_-_205391178 0.42 ENST00000367153.4
ENST00000367151.2
ENST00000391936.2
ENST00000367149.3
LEMD1
LEM domain containing 1
chr1_+_214163033 0.40 ENST00000607425.1
PROX1
prospero homeobox 1
chr21_+_17792672 0.40 ENST00000602620.1
LINC00478
long intergenic non-protein coding RNA 478
chr7_+_23637763 0.40 ENST00000410069.1
CCDC126
coiled-coil domain containing 126
chr2_-_203735484 0.37 ENST00000420558.1
ENST00000418208.1
ICA1L
islet cell autoantigen 1,69kDa-like
chr4_+_30721968 0.37 ENST00000361762.2
PCDH7
protocadherin 7
chr5_+_110427983 0.36 ENST00000513710.2
ENST00000505303.1
WDR36
WD repeat domain 36
chr6_+_30951487 0.35 ENST00000486149.2
ENST00000376296.3
MUC21
mucin 21, cell surface associated
chr12_-_71031185 0.34 ENST00000548122.1
ENST00000551525.1
ENST00000550358.1
PTPRB
protein tyrosine phosphatase, receptor type, B
chr2_+_182756615 0.33 ENST00000431877.2
ENST00000320370.7
SSFA2
sperm specific antigen 2
chr15_+_25200108 0.32 ENST00000577949.1
ENST00000338094.6
ENST00000338327.4
ENST00000579070.1
ENST00000577565.1
SNURF
SNRPN
SNRPN upstream reading frame protein
small nuclear ribonucleoprotein polypeptide N
chr10_-_65028817 0.32 ENST00000542921.1
JMJD1C
jumonji domain containing 1C
chr5_+_118691706 0.32 ENST00000415806.2
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr18_-_24445664 0.32 ENST00000578776.1
AQP4
aquaporin 4
chr20_-_23066953 0.31 ENST00000246006.4
CD93
CD93 molecule
chr1_-_41328018 0.30 ENST00000372638.2
CITED4
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
chr1_+_32608566 0.29 ENST00000545542.1
KPNA6
karyopherin alpha 6 (importin alpha 7)
chr20_+_42574317 0.29 ENST00000358131.5
TOX2
TOX high mobility group box family member 2
chr9_-_13175823 0.29 ENST00000545857.1
MPDZ
multiple PDZ domain protein
chr4_-_120988229 0.29 ENST00000296509.6
MAD2L1
MAD2 mitotic arrest deficient-like 1 (yeast)
chr1_+_12123414 0.28 ENST00000263932.2
TNFRSF8
tumor necrosis factor receptor superfamily, member 8
chr6_-_11232891 0.28 ENST00000379433.5
ENST00000379446.5
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr15_+_25200074 0.28 ENST00000390687.4
ENST00000584968.1
ENST00000346403.6
ENST00000554227.2
SNRPN
small nuclear ribonucleoprotein polypeptide N
chr21_+_42539701 0.27 ENST00000330333.6
ENST00000328735.6
ENST00000347667.5
BACE2
beta-site APP-cleaving enzyme 2
chr6_+_38690622 0.27 ENST00000327475.6
DNAH8
dynein, axonemal, heavy chain 8
chr14_-_25103388 0.27 ENST00000526004.1
ENST00000415355.3
GZMB
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr14_-_25103472 0.26 ENST00000216341.4
ENST00000382542.1
ENST00000382540.1
GZMB
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr16_+_82090028 0.26 ENST00000568090.1
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr5_+_140602904 0.25 ENST00000515856.2
ENST00000239449.4
PCDHB14
protocadherin beta 14
chr19_-_54604083 0.25 ENST00000391761.1
ENST00000356532.3
ENST00000359649.4
ENST00000358375.4
ENST00000391760.1
ENST00000351806.4
OSCAR
osteoclast associated, immunoglobulin-like receptor
chr3_-_45957534 0.24 ENST00000536047.1
LZTFL1
leucine zipper transcription factor-like 1
chr13_-_74708372 0.23 ENST00000377666.4
KLF12
Kruppel-like factor 12
chr11_-_119252359 0.22 ENST00000455332.2
USP2
ubiquitin specific peptidase 2
chr1_-_179834311 0.22 ENST00000553856.1
IFRG15
Homo sapiens torsin A interacting protein 2 (TOR1AIP2), transcript variant 1, mRNA.
chr12_-_51402984 0.22 ENST00000545993.2
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr3_+_52448539 0.22 ENST00000461861.1
PHF7
PHD finger protein 7
chr3_-_45957088 0.20 ENST00000539217.1
LZTFL1
leucine zipper transcription factor-like 1
chr12_-_71031220 0.20 ENST00000334414.6
PTPRB
protein tyrosine phosphatase, receptor type, B
chr20_-_18477862 0.20 ENST00000337227.4
RBBP9
retinoblastoma binding protein 9
chrX_+_102192200 0.20 ENST00000218249.5
RAB40AL
RAB40A, member RAS oncogene family-like
chr11_-_14379997 0.19 ENST00000526063.1
ENST00000532814.1
RRAS2
related RAS viral (r-ras) oncogene homolog 2
chr17_+_32582293 0.19 ENST00000580907.1
ENST00000225831.4
CCL2
chemokine (C-C motif) ligand 2
chr1_-_8086343 0.18 ENST00000474874.1
ENST00000469499.1
ENST00000377482.5
ERRFI1
ERBB receptor feedback inhibitor 1
chr5_+_102201687 0.17 ENST00000304400.7
PAM
peptidylglycine alpha-amidating monooxygenase
chr5_+_138609441 0.17 ENST00000509990.1
ENST00000506147.1
ENST00000512107.1
MATR3
matrin 3
chr6_-_27860956 0.17 ENST00000359611.2
HIST1H2AM
histone cluster 1, H2am
chr11_-_119252425 0.17 ENST00000260187.2
USP2
ubiquitin specific peptidase 2
chr3_-_73673991 0.17 ENST00000308537.4
ENST00000263666.4
PDZRN3
PDZ domain containing ring finger 3
chr12_-_82152420 0.16 ENST00000552948.1
ENST00000548586.1
PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr15_-_23932437 0.16 ENST00000331837.4
NDN
necdin, melanoma antigen (MAGE) family member
chr1_+_114472481 0.16 ENST00000369555.2
HIPK1
homeodomain interacting protein kinase 1
chr2_-_204400113 0.16 ENST00000319170.5
RAPH1
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
chr8_+_11666649 0.16 ENST00000528643.1
ENST00000525777.1
FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr17_+_44588877 0.16 ENST00000576629.1
LRRC37A2
leucine rich repeat containing 37, member A2
chr4_-_10686373 0.15 ENST00000442825.2
CLNK
cytokine-dependent hematopoietic cell linker
chr2_-_175462456 0.15 ENST00000409891.1
ENST00000410117.1
WIPF1
WAS/WASL interacting protein family, member 1
chrX_-_50386648 0.15 ENST00000460112.3
SHROOM4
shroom family member 4
chr2_+_68962014 0.15 ENST00000467265.1
ARHGAP25
Rho GTPase activating protein 25
chr1_-_94586651 0.14 ENST00000535735.1
ENST00000370225.3
ABCA4
ATP-binding cassette, sub-family A (ABC1), member 4
chr1_+_150245177 0.14 ENST00000369098.3
C1orf54
chromosome 1 open reading frame 54
chr9_-_111619239 0.14 ENST00000374667.3
ACTL7B
actin-like 7B
chr12_-_55367361 0.14 ENST00000532804.1
ENST00000531122.1
ENST00000533446.1
TESPA1
thymocyte expressed, positive selection associated 1
chr17_+_34640031 0.14 ENST00000339270.6
ENST00000482104.1
CCL4L2
chemokine (C-C motif) ligand 4-like 2
chr17_+_34538310 0.14 ENST00000444414.1
ENST00000378350.4
ENST00000389068.5
ENST00000588929.1
ENST00000589079.1
ENST00000589336.1
ENST00000400702.4
ENST00000591167.1
ENST00000586598.1
ENST00000591637.1
ENST00000378352.4
ENST00000358756.5
CCL4L1
chemokine (C-C motif) ligand 4-like 1
chr20_+_42136308 0.14 ENST00000434666.1
ENST00000427442.2
ENST00000439769.1
ENST00000418998.1
L3MBTL1
l(3)mbt-like 1 (Drosophila)
chr11_+_36616044 0.13 ENST00000334307.5
ENST00000531554.1
ENST00000347206.4
ENST00000534635.1
ENST00000446510.2
ENST00000530697.1
ENST00000527108.1
C11orf74
chromosome 11 open reading frame 74
chr3_-_98235962 0.13 ENST00000513873.1
CLDND1
claudin domain containing 1
chr6_-_30524951 0.13 ENST00000376621.3
GNL1
guanine nucleotide binding protein-like 1
chr4_-_46391931 0.13 ENST00000381620.4
GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr6_+_147527103 0.13 ENST00000179882.6
STXBP5
syntaxin binding protein 5 (tomosyn)
chr6_-_117150198 0.12 ENST00000310357.3
ENST00000368549.3
ENST00000530250.1
GPRC6A
G protein-coupled receptor, family C, group 6, member A
chr1_+_45965725 0.12 ENST00000401061.4
MMACHC
methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
chr8_-_37594944 0.12 ENST00000330539.1
RP11-863K10.7
Uncharacterized protein
chr5_+_102201722 0.12 ENST00000274392.9
ENST00000455264.2
PAM
peptidylglycine alpha-amidating monooxygenase
chr1_+_78383813 0.12 ENST00000342754.5
NEXN
nexilin (F actin binding protein)
chr17_+_34639793 0.12 ENST00000394465.2
ENST00000394463.2
ENST00000378342.4
CCL4L2
chemokine (C-C motif) ligand 4-like 2
chr15_-_64386120 0.12 ENST00000300030.3
FAM96A
family with sequence similarity 96, member A
chr15_-_64385981 0.11 ENST00000557835.1
ENST00000380290.3
ENST00000559950.1
FAM96A
family with sequence similarity 96, member A
chr1_+_26759295 0.11 ENST00000430232.1
DHDDS
dehydrodolichyl diphosphate synthase
chr16_-_29757272 0.11 ENST00000329410.3
C16orf54
chromosome 16 open reading frame 54
chr11_+_63655987 0.11 ENST00000509502.2
ENST00000512060.1
MARK2
MAP/microtubule affinity-regulating kinase 2
chr8_-_117886955 0.11 ENST00000297338.2
RAD21
RAD21 homolog (S. pombe)
chr2_-_16804320 0.11 ENST00000355549.2
FAM49A
family with sequence similarity 49, member A
chr11_+_7618413 0.11 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr8_+_123793633 0.11 ENST00000314393.4
ZHX2
zinc fingers and homeoboxes 2
chr15_+_96869165 0.11 ENST00000421109.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr5_+_74011328 0.11 ENST00000513336.1
HEXB
hexosaminidase B (beta polypeptide)
chr14_-_24553834 0.11 ENST00000397002.2
NRL
neural retina leucine zipper
chr4_-_46391805 0.11 ENST00000540012.1
GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr4_-_10686475 0.10 ENST00000226951.6
CLNK
cytokine-dependent hematopoietic cell linker
chr19_-_7766991 0.10 ENST00000597921.1
ENST00000346664.5
FCER2
Fc fragment of IgE, low affinity II, receptor for (CD23)
chr11_-_77531752 0.10 ENST00000440064.2
ENST00000528095.1
RSF1
remodeling and spacing factor 1
chr3_-_49851313 0.10 ENST00000333486.3
UBA7
ubiquitin-like modifier activating enzyme 7
chr14_+_38677123 0.10 ENST00000267377.2
SSTR1
somatostatin receptor 1
chr11_+_73358594 0.09 ENST00000227214.6
ENST00000398494.4
ENST00000543085.1
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr2_+_234526272 0.09 ENST00000373450.4
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr1_-_205649580 0.09 ENST00000367145.3
SLC45A3
solute carrier family 45, member 3
chr1_+_114472222 0.09 ENST00000369558.1
ENST00000369561.4
HIPK1
homeodomain interacting protein kinase 1
chr9_-_131486367 0.09 ENST00000372663.4
ENST00000406904.2
ENST00000452105.1
ENST00000372672.2
ENST00000372667.5
ZDHHC12
zinc finger, DHHC-type containing 12
chr1_+_109256067 0.09 ENST00000271311.2
FNDC7
fibronectin type III domain containing 7
chr11_+_118175132 0.09 ENST00000361763.4
CD3E
CD3e molecule, epsilon (CD3-TCR complex)
chr1_+_149754227 0.09 ENST00000444948.1
ENST00000369168.4
FCGR1A
Fc fragment of IgG, high affinity Ia, receptor (CD64)
chr3_+_158991025 0.08 ENST00000337808.6
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr2_-_202316260 0.08 ENST00000332624.3
TRAK2
trafficking protein, kinesin binding 2
chr3_+_158787041 0.08 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr1_+_150245099 0.08 ENST00000369099.3
C1orf54
chromosome 1 open reading frame 54
chr13_+_73629107 0.08 ENST00000539231.1
KLF5
Kruppel-like factor 5 (intestinal)
chr22_+_38201114 0.08 ENST00000340857.2
H1F0
H1 histone family, member 0
chr13_-_28545276 0.08 ENST00000381020.7
CDX2
caudal type homeobox 2
chr11_+_118230287 0.08 ENST00000252108.3
ENST00000431736.2
UBE4A
ubiquitination factor E4A
chr2_-_197226875 0.07 ENST00000409111.1
HECW2
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr2_+_234686976 0.07 ENST00000389758.3
MROH2A
maestro heat-like repeat family member 2A
chr7_+_55433131 0.07 ENST00000254770.2
LANCL2
LanC lantibiotic synthetase component C-like 2 (bacterial)
chr11_-_62997124 0.07 ENST00000306494.6
SLC22A25
solute carrier family 22, member 25
chr5_+_126984710 0.07 ENST00000379445.3
CTXN3
cortexin 3
chrX_-_72434628 0.07 ENST00000536638.1
ENST00000373517.3
NAP1L2
nucleosome assembly protein 1-like 2
chr4_-_46392290 0.07 ENST00000515082.1
GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr3_+_148508845 0.07 ENST00000491148.1
CPB1
carboxypeptidase B1 (tissue)
chr6_+_84222220 0.06 ENST00000369700.3
PRSS35
protease, serine, 35
chr15_+_91643442 0.06 ENST00000394232.1
SV2B
synaptic vesicle glycoprotein 2B
chr7_+_129015484 0.06 ENST00000490911.1
AHCYL2
adenosylhomocysteinase-like 2
chr15_+_34638066 0.06 ENST00000333756.4
NUTM1
NUT midline carcinoma, family member 1
chr7_-_15726296 0.06 ENST00000262041.5
MEOX2
mesenchyme homeobox 2
chr7_-_122840015 0.06 ENST00000194130.2
SLC13A1
solute carrier family 13 (sodium/sulfate symporter), member 1
chr3_+_179370517 0.06 ENST00000263966.3
USP13
ubiquitin specific peptidase 13 (isopeptidase T-3)
chr1_-_190446759 0.06 ENST00000367462.3
BRINP3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chrX_-_138914394 0.06 ENST00000327569.3
ENST00000361648.2
ENST00000370543.1
ENST00000359686.2
ATP11C
ATPase, class VI, type 11C
chr3_+_121311966 0.04 ENST00000338040.4
FBXO40
F-box protein 40
chrX_-_139866723 0.04 ENST00000370532.2
CDR1
cerebellar degeneration-related protein 1, 34kDa
chr14_-_37642016 0.04 ENST00000331299.5
SLC25A21
solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
chr2_-_204400013 0.04 ENST00000374489.2
ENST00000374488.2
ENST00000308091.4
ENST00000453034.1
ENST00000420371.1
RAPH1
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
chr8_+_49984894 0.04 ENST00000522267.1
ENST00000399653.4
ENST00000303202.8
C8orf22
chromosome 8 open reading frame 22
chr15_+_64386261 0.04 ENST00000560829.1
SNX1
sorting nexin 1
chr7_+_138818490 0.04 ENST00000430935.1
ENST00000495038.1
ENST00000474035.2
ENST00000478836.2
ENST00000464848.1
ENST00000343187.4
TTC26
tetratricopeptide repeat domain 26
chr14_-_25078864 0.03 ENST00000216338.4
ENST00000557220.2
ENST00000382548.4
GZMH
granzyme H (cathepsin G-like 2, protein h-CCPX)
chr3_+_189507460 0.03 ENST00000434928.1
TP63
tumor protein p63
chr1_+_152691998 0.03 ENST00000368775.2
C1orf68
chromosome 1 open reading frame 68
chr10_+_75541796 0.03 ENST00000372837.3
ENST00000372833.5
CHCHD1
coiled-coil-helix-coiled-coil-helix domain containing 1
chr15_-_100882191 0.03 ENST00000268070.4
ADAMTS17
ADAM metallopeptidase with thrombospondin type 1 motif, 17
chr3_+_189507523 0.03 ENST00000437221.1
ENST00000392463.2
ENST00000392461.3
ENST00000449992.1
ENST00000456148.1
TP63
tumor protein p63
chr13_-_45915221 0.03 ENST00000309246.5
ENST00000379060.4
ENST00000379055.1
ENST00000527226.1
ENST00000379056.1
TPT1
tumor protein, translationally-controlled 1
chr4_+_166300084 0.03 ENST00000402744.4
CPE
carboxypeptidase E
chr3_+_153839149 0.02 ENST00000465093.1
ENST00000465817.1
ARHGEF26
Rho guanine nucleotide exchange factor (GEF) 26
chr17_-_62308087 0.02 ENST00000583097.1
TEX2
testis expressed 2
chr12_+_52281744 0.02 ENST00000301190.6
ENST00000538991.1
ANKRD33
ankyrin repeat domain 33
chrX_+_134887233 0.02 ENST00000443882.1
CT45A3
cancer/testis antigen family 45, member A3
chr2_-_134326009 0.02 ENST00000409261.1
ENST00000409213.1
NCKAP5
NCK-associated protein 5
chr3_-_185655795 0.01 ENST00000342294.4
ENST00000382191.4
ENST00000453386.2
TRA2B
transformer 2 beta homolog (Drosophila)
chr18_-_51107372 0.01 ENST00000565170.1
RP11-202D1.2
RP11-202D1.2
chr10_-_101769617 0.01 ENST00000324109.4
ENST00000342239.3
DNMBP
dynamin binding protein
chr7_+_31569365 0.01 ENST00000454513.1
ENST00000451887.2
CCDC129
coiled-coil domain containing 129
chr7_-_76829125 0.01 ENST00000248598.5
FGL2
fibrinogen-like 2
chr2_-_183731882 0.01 ENST00000295113.4
FRZB
frizzled-related protein
chr17_-_17740287 0.01 ENST00000355815.4
ENST00000261646.5
SREBF1
sterol regulatory element binding transcription factor 1
chr14_-_46185155 0.01 ENST00000555442.1
RP11-369C8.1
RP11-369C8.1
chr3_+_132379154 0.01 ENST00000468022.1
ENST00000473651.1
ENST00000494238.2
UBA5
ubiquitin-like modifier activating enzyme 5
chr17_+_7461580 0.00 ENST00000483039.1
ENST00000396542.1
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr11_-_10828892 0.00 ENST00000525681.1
EIF4G2
eukaryotic translation initiation factor 4 gamma, 2
chr1_-_108735440 0.00 ENST00000370041.4
SLC25A24
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24

Network of associatons between targets according to the STRING database.

First level regulatory network of STAT6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.2 0.9 GO:0000821 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.1 0.4 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.1 0.5 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 0.4 GO:0002194 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.1 0.6 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 0.8 GO:0008218 bioluminescence(GO:0008218)
0.1 0.3 GO:0032759 TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
0.1 2.1 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.1 0.8 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 0.5 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.1 0.3 GO:0018032 protein amidation(GO:0018032)
0.1 0.5 GO:0030578 PML body organization(GO:0030578)
0.1 1.2 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 0.2 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.1 0.6 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.1 0.3 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.4 GO:0048733 sebaceous gland development(GO:0048733)
0.0 1.2 GO:0072189 ureter development(GO:0072189)
0.0 0.2 GO:0015692 lead ion transport(GO:0015692)
0.0 1.1 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.1 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.0 0.1 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.0 0.3 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.2 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0 0.1 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.1 GO:0015766 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0 1.0 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.2 GO:1903243 negative regulation of cardiac muscle adaptation(GO:0010616) negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243)
0.0 0.3 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0 2.0 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.1 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.0 0.1 GO:0060849 radial pattern formation(GO:0009956) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.0 0.1 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.0 0.1 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.0 0.1 GO:0070980 biphenyl catabolic process(GO:0070980)
0.0 0.1 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.1 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.0 0.3 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.3 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.4 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.1 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 1.1 GO:0006968 cellular defense response(GO:0006968)
0.0 0.3 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.9 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.1 0.4 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.2 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.6 GO:0005687 U4 snRNP(GO:0005687)
0.0 0.3 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.1 GO:0000798 nuclear cohesin complex(GO:0000798)
0.0 2.2 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.3 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.3 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.1 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.4 GO:0031092 platelet alpha granule membrane(GO:0031092)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1 0.6 GO:0004359 glutaminase activity(GO:0004359)
0.1 0.8 GO:0097643 amylin receptor activity(GO:0097643)
0.1 0.6 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.3 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1 0.4 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 0.3 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.1 2.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.9 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.2 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 0.1 GO:0032093 SAM domain binding(GO:0032093)
0.0 0.4 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.2 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.2 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.0 0.1 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.0 1.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.6 GO:0003680 AT DNA binding(GO:0003680)
0.0 1.3 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 1.0 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.5 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.1 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.3 GO:0008503 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.5 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.7 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.9 GO:0030552 cAMP binding(GO:0030552)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.2 GO:0015250 water channel activity(GO:0015250)
0.0 0.3 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.1 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.5 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.4 GO:0005109 frizzled binding(GO:0005109)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.1 PID IFNG PATHWAY IFN-gamma pathway
0.0 1.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.8 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.8 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 1.3 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.4 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 1.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 1.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.6 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.9 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.9 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.5 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.5 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 1.1 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)