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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for T

Z-value: 0.47

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Transcription factors associated with T

Gene Symbol Gene ID Gene Info
T
ENSG00000164458.5 T

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Thg19_v2_chr6_-_166582107_166582188-0.174.2e-01Click!

Activity profile of T motif

Sorted Z-values of T motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_102759199 1.30 ENST00000409288.1
ENST00000410023.1
IL1R1
interleukin 1 receptor, type I
chr1_-_205290865 1.13 ENST00000367157.3
NUAK2
NUAK family, SNF1-like kinase, 2
chr19_-_6690723 1.02 ENST00000601008.1
C3
complement component 3
chr19_+_10197463 0.93 ENST00000590378.1
ENST00000397881.3
C19orf66
chromosome 19 open reading frame 66
chr17_+_26662597 0.90 ENST00000544907.2
TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr17_-_20370847 0.83 ENST00000423676.3
ENST00000324290.5
LGALS9B
lectin, galactoside-binding, soluble, 9B
chr12_+_22778291 0.80 ENST00000545979.1
ETNK1
ethanolamine kinase 1
chr3_+_127770455 0.68 ENST00000464451.1
SEC61A1
Sec61 alpha 1 subunit (S. cerevisiae)
chr19_-_44174330 0.67 ENST00000340093.3
PLAUR
plasminogen activator, urokinase receptor
chr17_-_74497432 0.60 ENST00000590288.1
ENST00000313080.4
ENST00000592123.1
ENST00000591255.1
ENST00000585989.1
ENST00000591697.1
ENST00000389760.4
RHBDF2
rhomboid 5 homolog 2 (Drosophila)
chr12_-_117318788 0.57 ENST00000550505.1
HRK
harakiri, BCL2 interacting protein (contains only BH3 domain)
chr5_+_14664762 0.54 ENST00000284274.4
FAM105B
family with sequence similarity 105, member B
chr11_-_85779971 0.49 ENST00000393346.3
PICALM
phosphatidylinositol binding clathrin assembly protein
chr5_+_54320078 0.46 ENST00000231009.2
GZMK
granzyme K (granzyme 3; tryptase II)
chr2_+_171571827 0.46 ENST00000375281.3
SP5
Sp5 transcription factor
chr2_-_152146385 0.44 ENST00000414946.1
ENST00000243346.5
NMI
N-myc (and STAT) interactor
chr19_-_44174305 0.44 ENST00000601723.1
ENST00000339082.3
PLAUR
plasminogen activator, urokinase receptor
chr2_+_162087577 0.42 ENST00000439442.1
TANK
TRAF family member-associated NFKB activator
chr1_-_85930246 0.42 ENST00000426972.3
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr21_+_25801041 0.42 ENST00000453784.2
ENST00000423581.1
AP000476.1
AP000476.1
chr3_-_66551351 0.41 ENST00000273261.3
LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chr2_-_208030647 0.39 ENST00000309446.6
KLF7
Kruppel-like factor 7 (ubiquitous)
chr3_-_66551397 0.39 ENST00000383703.3
LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chr17_+_19281034 0.36 ENST00000308406.5
ENST00000299612.7
MAPK7
mitogen-activated protein kinase 7
chr6_+_83073334 0.36 ENST00000369750.3
TPBG
trophoblast glycoprotein
chr2_+_149894968 0.34 ENST00000409642.3
LYPD6B
LY6/PLAUR domain containing 6B
chr2_+_149895207 0.33 ENST00000409876.1
LYPD6B
LY6/PLAUR domain containing 6B
chr19_-_10514184 0.32 ENST00000589629.1
ENST00000222005.2
CDC37
cell division cycle 37
chr20_+_32951070 0.32 ENST00000535650.1
ENST00000262650.6
ITCH
itchy E3 ubiquitin protein ligase
chr1_+_114472481 0.31 ENST00000369555.2
HIPK1
homeodomain interacting protein kinase 1
chr19_+_7030589 0.31 ENST00000329753.5
MBD3L5
methyl-CpG binding domain protein 3-like 5
chr7_-_142176790 0.30 ENST00000390369.2
TRBV7-4
T cell receptor beta variable 7-4 (gene/pseudogene)
chr15_+_60296421 0.30 ENST00000396057.4
FOXB1
forkhead box B1
chr1_+_114471809 0.29 ENST00000426820.2
HIPK1
homeodomain interacting protein kinase 1
chr19_-_1021113 0.29 ENST00000333175.5
ENST00000356663.3
TMEM259
transmembrane protein 259
chr17_-_26662440 0.29 ENST00000578122.1
IFT20
intraflagellar transport 20 homolog (Chlamydomonas)
chr12_+_54379569 0.28 ENST00000513209.1
RP11-834C11.12
RP11-834C11.12
chr19_-_17958832 0.27 ENST00000458235.1
JAK3
Janus kinase 3
chr17_-_26662464 0.26 ENST00000579419.1
ENST00000585313.1
ENST00000395418.3
ENST00000578985.1
ENST00000577498.1
ENST00000585089.1
ENST00000357896.3
IFT20
intraflagellar transport 20 homolog (Chlamydomonas)
chr19_+_7049332 0.26 ENST00000381393.3
MBD3L2
methyl-CpG binding domain protein 3-like 2
chr7_+_134576317 0.26 ENST00000424922.1
ENST00000495522.1
CALD1
caldesmon 1
chr17_-_19281203 0.26 ENST00000487415.2
B9D1
B9 protein domain 1
chr17_+_34431212 0.26 ENST00000394495.1
CCL4
chemokine (C-C motif) ligand 4
chrX_+_16804544 0.25 ENST00000380122.5
ENST00000398155.4
TXLNG
taxilin gamma
chr3_-_52443799 0.24 ENST00000470173.1
ENST00000296288.5
BAP1
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr20_+_3190006 0.24 ENST00000380113.3
ENST00000455664.2
ENST00000399838.3
ITPA
inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
chr10_-_97050777 0.23 ENST00000329399.6
PDLIM1
PDZ and LIM domain 1
chr1_-_26633067 0.23 ENST00000421827.2
ENST00000374215.1
ENST00000374223.1
ENST00000357089.4
ENST00000535108.1
ENST00000314675.7
ENST00000436301.2
ENST00000423664.1
ENST00000374221.3
UBXN11
UBX domain protein 11
chrX_+_153665248 0.23 ENST00000447750.2
GDI1
GDP dissociation inhibitor 1
chr7_-_81399411 0.22 ENST00000423064.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr14_+_95078714 0.22 ENST00000393078.3
ENST00000393080.4
ENST00000467132.1
SERPINA3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr12_-_49351228 0.21 ENST00000541959.1
ENST00000447318.2
ARF3
ADP-ribosylation factor 3
chr17_+_17942684 0.21 ENST00000376345.3
GID4
GID complex subunit 4
chr7_-_994302 0.20 ENST00000265846.5
ADAP1
ArfGAP with dual PH domains 1
chr1_+_27648648 0.20 ENST00000374076.4
TMEM222
transmembrane protein 222
chr3_+_195413160 0.20 ENST00000599448.1
LINC00969
long intergenic non-protein coding RNA 969
chr17_+_7533439 0.20 ENST00000441599.2
ENST00000380450.4
ENST00000416273.3
ENST00000575903.1
ENST00000576830.1
ENST00000571153.1
ENST00000575618.1
ENST00000576152.1
SHBG
sex hormone-binding globulin
chr1_+_27648709 0.19 ENST00000608611.1
ENST00000466759.1
ENST00000464813.1
ENST00000498220.1
TMEM222
transmembrane protein 222
chr12_+_57610562 0.18 ENST00000349394.5
NXPH4
neurexophilin 4
chr12_-_53074182 0.18 ENST00000252244.3
KRT1
keratin 1
chr12_-_49351303 0.18 ENST00000256682.4
ARF3
ADP-ribosylation factor 3
chr19_+_11546440 0.18 ENST00000589126.1
ENST00000588269.1
ENST00000587509.1
ENST00000592741.1
ENST00000593101.1
ENST00000587327.1
PRKCSH
protein kinase C substrate 80K-H
chr7_-_28220354 0.17 ENST00000283928.5
JAZF1
JAZF zinc finger 1
chr16_-_2314222 0.17 ENST00000566397.1
RNPS1
RNA binding protein S1, serine-rich domain
chr19_+_55281260 0.17 ENST00000336077.6
ENST00000291633.7
KIR2DL1
killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
chr17_+_34430980 0.17 ENST00000250151.4
CCL4
chemokine (C-C motif) ligand 4
chr2_+_223162866 0.17 ENST00000295226.1
CCDC140
coiled-coil domain containing 140
chr2_+_108905325 0.16 ENST00000438339.1
ENST00000409880.1
ENST00000437390.2
SULT1C2
sulfotransferase family, cytosolic, 1C, member 2
chr1_+_114472222 0.16 ENST00000369558.1
ENST00000369561.4
HIPK1
homeodomain interacting protein kinase 1
chr7_+_110731062 0.16 ENST00000308478.5
ENST00000451085.1
ENST00000422987.3
ENST00000421101.1
LRRN3
leucine rich repeat neuronal 3
chr22_+_35776828 0.16 ENST00000216117.8
HMOX1
heme oxygenase (decycling) 1
chr20_+_32951041 0.16 ENST00000374864.4
ITCH
itchy E3 ubiquitin protein ligase
chr19_+_11546153 0.16 ENST00000591946.1
ENST00000252455.2
ENST00000412601.1
PRKCSH
protein kinase C substrate 80K-H
chr6_+_131958436 0.16 ENST00000357639.3
ENST00000543135.1
ENST00000427148.2
ENST00000358229.5
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr1_+_39456895 0.16 ENST00000432648.3
ENST00000446189.2
ENST00000372984.4
AKIRIN1
akirin 1
chr5_-_112257914 0.15 ENST00000513339.1
ENST00000545426.1
ENST00000504247.1
REEP5
receptor accessory protein 5
chr2_+_108905095 0.15 ENST00000251481.6
ENST00000326853.5
SULT1C2
sulfotransferase family, cytosolic, 1C, member 2
chr7_-_38370536 0.15 ENST00000390343.2
TRGV8
T cell receptor gamma variable 8
chr5_-_137610300 0.14 ENST00000274721.3
GFRA3
GDNF family receptor alpha 3
chr5_-_137610254 0.14 ENST00000378362.3
GFRA3
GDNF family receptor alpha 3
chr6_+_29079668 0.14 ENST00000377169.1
OR2J3
olfactory receptor, family 2, subfamily J, member 3
chr17_+_34538310 0.14 ENST00000444414.1
ENST00000378350.4
ENST00000389068.5
ENST00000588929.1
ENST00000589079.1
ENST00000589336.1
ENST00000400702.4
ENST00000591167.1
ENST00000586598.1
ENST00000591637.1
ENST00000378352.4
ENST00000358756.5
CCL4L1
chemokine (C-C motif) ligand 4-like 1
chr11_-_66112555 0.14 ENST00000425825.2
ENST00000359957.3
BRMS1
breast cancer metastasis suppressor 1
chr10_+_4868460 0.13 ENST00000532248.1
ENST00000345253.5
ENST00000334019.4
AKR1E2
aldo-keto reductase family 1, member E2
chr9_-_14722715 0.13 ENST00000380911.3
CER1
cerberus 1, DAN family BMP antagonist
chr19_+_55235969 0.13 ENST00000402254.2
ENST00000538269.1
ENST00000541392.1
ENST00000291860.1
ENST00000396284.2
KIR3DL1
KIR3DL3
KIR2DL4
killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3
killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
chr7_-_76255444 0.13 ENST00000454397.1
POMZP3
POM121 and ZP3 fusion
chr1_+_92417716 0.13 ENST00000402388.1
BRDT
bromodomain, testis-specific
chr2_+_233320827 0.13 ENST00000295463.3
ALPI
alkaline phosphatase, intestinal
chr6_-_26124138 0.12 ENST00000314332.5
ENST00000396984.1
HIST1H2BC
histone cluster 1, H2bc
chr19_+_11546093 0.12 ENST00000591462.1
PRKCSH
protein kinase C substrate 80K-H
chr17_-_74533734 0.12 ENST00000589342.1
CYGB
cytoglobin
chr1_+_89150245 0.11 ENST00000370513.5
PKN2
protein kinase N2
chr1_-_24126051 0.11 ENST00000445705.1
GALE
UDP-galactose-4-epimerase
chr5_+_17444119 0.11 ENST00000503267.1
ENST00000504998.1
RP11-321E2.4
RP11-321E2.4
chr3_-_52002403 0.11 ENST00000490063.1
ENST00000468324.1
ENST00000497653.1
ENST00000484633.1
PCBP4
poly(rC) binding protein 4
chr4_+_26322409 0.11 ENST00000514807.1
ENST00000348160.4
ENST00000509158.1
ENST00000355476.3
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr9_+_36572851 0.11 ENST00000298048.2
ENST00000538311.1
ENST00000536987.1
ENST00000545008.1
ENST00000536860.1
ENST00000536329.1
ENST00000541717.1
ENST00000543751.1
MELK
maternal embryonic leucine zipper kinase
chr9_-_117150303 0.11 ENST00000312033.3
AKNA
AT-hook transcription factor
chr1_+_35225339 0.11 ENST00000339480.1
GJB4
gap junction protein, beta 4, 30.3kDa
chr21_+_19617140 0.11 ENST00000299295.2
ENST00000338326.3
CHODL
chondrolectin
chr5_+_50678921 0.11 ENST00000230658.7
ISL1
ISL LIM homeobox 1
chr12_-_6961050 0.10 ENST00000538862.2
CDCA3
cell division cycle associated 3
chr3_+_133502877 0.10 ENST00000466490.2
SRPRB
signal recognition particle receptor, B subunit
chr7_+_107110488 0.10 ENST00000304402.4
GPR22
G protein-coupled receptor 22
chr10_-_79789291 0.10 ENST00000372371.3
POLR3A
polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
chr6_+_24126350 0.09 ENST00000378491.4
ENST00000378478.1
ENST00000378477.2
NRSN1
neurensin 1
chr20_+_1115821 0.09 ENST00000435720.1
PSMF1
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr1_-_24126023 0.09 ENST00000429356.1
GALE
UDP-galactose-4-epimerase
chr1_+_78245303 0.09 ENST00000370791.3
ENST00000443751.2
FAM73A
family with sequence similarity 73, member A
chr4_+_123300664 0.09 ENST00000388725.2
ADAD1
adenosine deaminase domain containing 1 (testis-specific)
chr13_-_39564993 0.09 ENST00000423210.1
STOML3
stomatin (EPB72)-like 3
chr17_+_34640031 0.09 ENST00000339270.6
ENST00000482104.1
CCL4L2
chemokine (C-C motif) ligand 4-like 2
chr4_+_26322185 0.08 ENST00000361572.6
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr3_+_14058794 0.08 ENST00000424053.1
ENST00000528067.1
ENST00000429201.1
TPRXL
tetra-peptide repeat homeobox-like
chr4_+_128554081 0.08 ENST00000335251.6
ENST00000296461.5
INTU
inturned planar cell polarity protein
chr5_-_131330272 0.08 ENST00000379240.1
ACSL6
acyl-CoA synthetase long-chain family member 6
chr2_+_166152283 0.08 ENST00000375427.2
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr12_-_69326940 0.07 ENST00000549781.1
ENST00000548262.1
ENST00000551568.1
ENST00000548954.1
CPM
carboxypeptidase M
chr21_-_45078019 0.07 ENST00000542962.1
HSF2BP
heat shock transcription factor 2 binding protein
chr3_+_167453493 0.07 ENST00000295777.5
ENST00000472747.2
SERPINI1
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr5_+_140557371 0.07 ENST00000239444.2
PCDHB8
protocadherin beta 8
chr1_+_114471972 0.07 ENST00000369559.4
ENST00000369554.2
HIPK1
homeodomain interacting protein kinase 1
chr10_-_115423792 0.07 ENST00000369360.3
ENST00000360478.3
ENST00000359988.3
ENST00000369358.4
NRAP
nebulin-related anchoring protein
chr7_-_81399329 0.07 ENST00000453411.1
ENST00000444829.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr12_+_65672702 0.06 ENST00000538045.1
ENST00000535239.1
MSRB3
methionine sulfoxide reductase B3
chr1_+_203765437 0.06 ENST00000550078.1
ZBED6
zinc finger, BED-type containing 6
chr17_+_34639793 0.06 ENST00000394465.2
ENST00000394463.2
ENST00000378342.4
CCL4L2
chemokine (C-C motif) ligand 4-like 2
chr7_+_117864815 0.06 ENST00000433239.1
ANKRD7
ankyrin repeat domain 7
chr8_+_7801144 0.06 ENST00000443676.1
ZNF705B
zinc finger protein 705B
chr7_-_87849340 0.06 ENST00000419179.1
ENST00000265729.2
SRI
sorcin
chr20_-_1309809 0.06 ENST00000360779.3
SDCBP2
syndecan binding protein (syntenin) 2
chr2_+_122494676 0.06 ENST00000455432.1
TSN
translin
chr17_+_57970469 0.06 ENST00000443572.2
ENST00000406116.3
ENST00000225577.4
ENST00000393021.3
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
chr22_-_41215291 0.06 ENST00000542412.1
ENST00000544408.1
SLC25A17
solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
chr18_-_77276057 0.05 ENST00000597412.1
AC018445.1
Uncharacterized protein
chr15_-_34502197 0.05 ENST00000557877.1
KATNBL1
katanin p80 subunit B-like 1
chr7_-_81399438 0.05 ENST00000222390.5
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr8_-_141810634 0.05 ENST00000521986.1
ENST00000523539.1
ENST00000538769.1
PTK2
protein tyrosine kinase 2
chr15_-_83474806 0.05 ENST00000541889.1
ENST00000334574.8
ENST00000561368.1
FSD2
fibronectin type III and SPRY domain containing 2
chr20_+_1093891 0.05 ENST00000333082.3
ENST00000381898.4
ENST00000381899.4
PSMF1
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr6_+_159290917 0.05 ENST00000367072.1
C6orf99
chromosome 6 open reading frame 99
chr5_-_131329918 0.05 ENST00000357096.1
ENST00000431707.1
ENST00000434099.1
ACSL6
acyl-CoA synthetase long-chain family member 6
chr11_-_44972476 0.05 ENST00000527685.1
ENST00000308212.5
TP53I11
tumor protein p53 inducible protein 11
chr5_+_139554227 0.05 ENST00000261811.4
CYSTM1
cysteine-rich transmembrane module containing 1
chr1_-_204135450 0.04 ENST00000272190.8
ENST00000367195.2
REN
renin
chr19_+_3721719 0.04 ENST00000589378.1
ENST00000382008.3
TJP3
tight junction protein 3
chr4_-_69817481 0.04 ENST00000251566.4
UGT2A3
UDP glucuronosyltransferase 2 family, polypeptide A3
chr6_-_29013017 0.04 ENST00000377175.1
OR2W1
olfactory receptor, family 2, subfamily W, member 1
chr12_+_128399965 0.04 ENST00000540882.1
ENST00000542089.1
LINC00507
long intergenic non-protein coding RNA 507
chr19_-_18366182 0.04 ENST00000355502.3
PDE4C
phosphodiesterase 4C, cAMP-specific
chr10_+_51565188 0.04 ENST00000430396.2
ENST00000374087.4
ENST00000414907.2
NCOA4
nuclear receptor coactivator 4
chr13_+_24144509 0.04 ENST00000248484.4
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr2_+_133874577 0.04 ENST00000596384.1
AC011755.1
HCG2006742; Protein LOC100996685
chr1_-_156542328 0.04 ENST00000361170.2
IQGAP3
IQ motif containing GTPase activating protein 3
chr7_+_117864708 0.03 ENST00000357099.4
ENST00000265224.4
ENST00000486422.1
ENST00000417525.1
ANKRD7
ankyrin repeat domain 7
chr11_-_61197187 0.03 ENST00000449811.1
ENST00000413232.1
ENST00000340437.4
ENST00000539952.1
ENST00000544585.1
ENST00000450000.1
CPSF7
cleavage and polyadenylation specific factor 7, 59kDa
chr17_-_56084578 0.03 ENST00000582730.2
ENST00000584773.1
ENST00000585096.1
ENST00000258962.4
SRSF1
serine/arginine-rich splicing factor 1
chr4_-_73434498 0.03 ENST00000286657.4
ADAMTS3
ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr16_+_72459838 0.03 ENST00000564508.1
AC004158.3
AC004158.3
chr3_-_133614597 0.03 ENST00000285208.4
ENST00000460865.3
RAB6B
RAB6B, member RAS oncogene family
chr14_-_107211459 0.03 ENST00000390636.2
IGHV3-73
immunoglobulin heavy variable 3-73
chrX_+_79591003 0.03 ENST00000538312.1
FAM46D
family with sequence similarity 46, member D
chr7_-_229557 0.02 ENST00000514988.1
AC145676.2
Uncharacterized protein
chr16_+_69221028 0.02 ENST00000336278.4
SNTB2
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr7_-_752577 0.02 ENST00000544935.1
ENST00000430040.1
ENST00000456696.2
ENST00000406797.1
PRKAR1B
protein kinase, cAMP-dependent, regulatory, type I, beta
chr22_-_36031181 0.02 ENST00000594060.1
AL049747.1
AL049747.1
chr15_-_83621435 0.02 ENST00000450735.2
ENST00000426485.1
ENST00000399166.2
ENST00000304231.8
HOMER2
homer homolog 2 (Drosophila)
chr2_-_85636928 0.02 ENST00000449030.1
CAPG
capping protein (actin filament), gelsolin-like
chr11_+_133938955 0.02 ENST00000534549.1
ENST00000441717.3
JAM3
junctional adhesion molecule 3
chr3_-_57678772 0.02 ENST00000311128.5
DENND6A
DENN/MADD domain containing 6A
chr1_+_101702417 0.02 ENST00000305352.6
S1PR1
sphingosine-1-phosphate receptor 1
chr8_-_114449112 0.02 ENST00000455883.2
ENST00000352409.3
ENST00000297405.5
CSMD3
CUB and Sushi multiple domains 3
chr20_+_34129770 0.02 ENST00000348547.2
ENST00000357394.4
ENST00000447986.1
ENST00000279052.6
ENST00000416206.1
ENST00000411577.1
ENST00000413587.1
ERGIC3
ERGIC and golgi 3
chr4_-_186456652 0.02 ENST00000284767.5
ENST00000284770.5
PDLIM3
PDZ and LIM domain 3
chr1_+_33219592 0.02 ENST00000373481.3
KIAA1522
KIAA1522
chr15_-_81195510 0.02 ENST00000561295.1
RP11-351M8.1
Uncharacterized protein
chr16_-_88717423 0.02 ENST00000568278.1
ENST00000569359.1
ENST00000567174.1
CYBA
cytochrome b-245, alpha polypeptide
chr3_+_102153859 0.02 ENST00000306176.1
ENST00000466937.1
ZPLD1
zona pellucida-like domain containing 1
chr3_+_38307293 0.01 ENST00000311856.4
SLC22A13
solute carrier family 22 (organic anion/urate transporter), member 13
chr14_-_69619689 0.01 ENST00000389997.6
ENST00000557386.1
ENST00000554681.1
DCAF5
DDB1 and CUL4 associated factor 5
chr4_-_186456766 0.01 ENST00000284771.6
PDLIM3
PDZ and LIM domain 3
chr12_-_6960407 0.01 ENST00000540683.1
ENST00000229265.6
ENST00000535406.1
ENST00000422785.3
CDCA3
cell division cycle associated 3
chr11_+_133938820 0.01 ENST00000299106.4
ENST00000529443.2
JAM3
junctional adhesion molecule 3
chr5_+_85913721 0.01 ENST00000247655.3
ENST00000509578.1
ENST00000515763.1
COX7C
cytochrome c oxidase subunit VIIc
chr4_-_140005443 0.01 ENST00000510408.1
ENST00000420916.2
ENST00000358635.3
ELF2
E74-like factor 2 (ets domain transcription factor)
chr4_-_151936865 0.00 ENST00000535741.1
LRBA
LPS-responsive vesicle trafficking, beach and anchor containing
chr12_-_56709674 0.00 ENST00000551286.1
ENST00000549318.1
CNPY2
RP11-977G19.10
canopy FGF signaling regulator 2
Uncharacterized protein
chr6_-_106773291 0.00 ENST00000343245.3
ATG5
autophagy related 5
chr12_+_128399917 0.00 ENST00000544645.1
LINC00507
long intergenic non-protein coding RNA 507
chr12_-_52867569 0.00 ENST00000252250.6
KRT6C
keratin 6C
chr1_-_204165610 0.00 ENST00000367194.4
KISS1
KiSS-1 metastasis-suppressor

Network of associatons between targets according to the STRING database.

First level regulatory network of T

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.3 1.0 GO:0001798 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.3 1.1 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.2 0.7 GO:0039019 pronephric nephron development(GO:0039019)
0.2 0.8 GO:0032474 otolith morphogenesis(GO:0032474)
0.1 0.3 GO:0007412 axon target recognition(GO:0007412)
0.1 0.5 GO:0035519 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913) protein K29-linked ubiquitination(GO:0035519)
0.1 0.8 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.1 0.4 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.1 0.2 GO:0002731 negative regulation of dendritic cell cytokine production(GO:0002731) FasL biosynthetic process(GO:0045210)
0.1 0.5 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1 0.4 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.2 GO:1901189 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.1 0.2 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1 0.4 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1 0.4 GO:0051342 regulation of cyclic nucleotide catabolic process(GO:0030805) regulation of cAMP catabolic process(GO:0030820) regulation of purine nucleotide catabolic process(GO:0033121) regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.1 0.5 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 0.2 GO:0032764 heme oxidation(GO:0006788) smooth muscle hyperplasia(GO:0014806) negative regulation of mast cell cytokine production(GO:0032764)
0.1 0.2 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 0.1 GO:0071655 granulocyte colony-stimulating factor production(GO:0071611) regulation of granulocyte colony-stimulating factor production(GO:0071655)
0.0 0.1 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.0 0.1 GO:0001207 histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.0 0.3 GO:1902947 regulation of tau-protein kinase activity(GO:1902947)
0.0 0.9 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.4 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.0 0.8 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.2 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.2 GO:0009146 purine nucleoside triphosphate catabolic process(GO:0009146)
0.0 0.6 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.6 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.1 GO:0035803 egg coat formation(GO:0035803)
0.0 0.1 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.1 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.5 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 1.1 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.3 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
0.0 0.2 GO:0002767 immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.0 0.5 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.3 GO:0098779 mitophagy in response to mitochondrial depolarization(GO:0098779)
0.0 0.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.2 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.1 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.3 GO:0051923 sulfation(GO:0051923)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:1902636 kinociliary basal body(GO:1902636)
0.1 1.1 GO:0071438 invadopodium membrane(GO:0071438)
0.1 0.5 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.2 GO:0061574 ASAP complex(GO:0061574)
0.0 0.3 GO:0030478 actin cap(GO:0030478)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 0.1 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 1.2 GO:0035578 azurophil granule lumen(GO:0035578)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.3 1.3 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.1 0.5 GO:0002046 opsin binding(GO:0002046)
0.1 0.4 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 0.8 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.1 0.4 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.4 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.1 0.4 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 0.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 0.2 GO:0003978 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.0 0.7 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.1 GO:0050571 1,5-anhydro-D-fructose reductase activity(GO:0050571)
0.0 0.5 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.7 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.5 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 0.3 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.2 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.1 GO:0030109 HLA-B specific inhibitory MHC class I receptor activity(GO:0030109)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.4 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0016015 morphogen activity(GO:0016015)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 0.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.1 GO:0000150 recombinase activity(GO:0000150)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.1 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.7 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.2 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 1.3 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.2 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.4 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.8 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 1.1 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.5 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.4 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 1.3 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.3 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR