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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for T

Z-value: 0.47

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Transcription factors associated with T

Gene Symbol Gene ID Gene Info
ENSG00000164458.5 T

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Thg19_v2_chr6_-_166582107_166582188-0.174.2e-01Click!

Activity profile of T motif

Sorted Z-values of T motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_102759199 1.30 ENST00000409288.1
ENST00000410023.1
interleukin 1 receptor, type I
chr1_-_205290865 1.13 ENST00000367157.3
NUAK family, SNF1-like kinase, 2
chr19_-_6690723 1.02 ENST00000601008.1
complement component 3
chr19_+_10197463 0.93 ENST00000590378.1
ENST00000397881.3
chromosome 19 open reading frame 66
chr17_+_26662597 0.90 ENST00000544907.2
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr17_-_20370847 0.83 ENST00000423676.3
ENST00000324290.5
lectin, galactoside-binding, soluble, 9B
chr12_+_22778291 0.80 ENST00000545979.1
ethanolamine kinase 1
chr3_+_127770455 0.68 ENST00000464451.1
Sec61 alpha 1 subunit (S. cerevisiae)
chr19_-_44174330 0.67 ENST00000340093.3
plasminogen activator, urokinase receptor
chr17_-_74497432 0.60 ENST00000590288.1
ENST00000313080.4
ENST00000592123.1
ENST00000591255.1
ENST00000585989.1
ENST00000591697.1
ENST00000389760.4
rhomboid 5 homolog 2 (Drosophila)
chr12_-_117318788 0.57 ENST00000550505.1
harakiri, BCL2 interacting protein (contains only BH3 domain)
chr5_+_14664762 0.54 ENST00000284274.4
family with sequence similarity 105, member B
chr11_-_85779971 0.49 ENST00000393346.3
phosphatidylinositol binding clathrin assembly protein
chr5_+_54320078 0.46 ENST00000231009.2
granzyme K (granzyme 3; tryptase II)
chr2_+_171571827 0.46 ENST00000375281.3
Sp5 transcription factor
chr2_-_152146385 0.44 ENST00000414946.1
ENST00000243346.5
N-myc (and STAT) interactor
chr19_-_44174305 0.44 ENST00000601723.1
ENST00000339082.3
plasminogen activator, urokinase receptor
chr2_+_162087577 0.42 ENST00000439442.1
TRAF family member-associated NFKB activator
chr1_-_85930246 0.42 ENST00000426972.3
dimethylarginine dimethylaminohydrolase 1
chr21_+_25801041 0.42 ENST00000453784.2
ENST00000423581.1
AP000476.1
chr3_-_66551351 0.41 ENST00000273261.3
leucine-rich repeats and immunoglobulin-like domains 1
chr2_-_208030647 0.39 ENST00000309446.6
Kruppel-like factor 7 (ubiquitous)
chr3_-_66551397 0.39 ENST00000383703.3
leucine-rich repeats and immunoglobulin-like domains 1
chr17_+_19281034 0.36 ENST00000308406.5
ENST00000299612.7
mitogen-activated protein kinase 7
chr6_+_83073334 0.36 ENST00000369750.3
trophoblast glycoprotein
chr2_+_149894968 0.34 ENST00000409642.3
LY6/PLAUR domain containing 6B
chr2_+_149895207 0.33 ENST00000409876.1
LY6/PLAUR domain containing 6B
chr19_-_10514184 0.32 ENST00000589629.1
ENST00000222005.2
cell division cycle 37
chr20_+_32951070 0.32 ENST00000535650.1
ENST00000262650.6
itchy E3 ubiquitin protein ligase
chr1_+_114472481 0.31 ENST00000369555.2
homeodomain interacting protein kinase 1
chr19_+_7030589 0.31 ENST00000329753.5
methyl-CpG binding domain protein 3-like 5
chr7_-_142176790 0.30 ENST00000390369.2
T cell receptor beta variable 7-4 (gene/pseudogene)
chr15_+_60296421 0.30 ENST00000396057.4
forkhead box B1
chr1_+_114471809 0.29 ENST00000426820.2
homeodomain interacting protein kinase 1
chr19_-_1021113 0.29 ENST00000333175.5
ENST00000356663.3
transmembrane protein 259
chr17_-_26662440 0.29 ENST00000578122.1
intraflagellar transport 20 homolog (Chlamydomonas)
chr12_+_54379569 0.28 ENST00000513209.1
RP11-834C11.12
chr19_-_17958832 0.27 ENST00000458235.1
Janus kinase 3
chr17_-_26662464 0.26 ENST00000579419.1
ENST00000585313.1
ENST00000395418.3
ENST00000578985.1
ENST00000577498.1
ENST00000585089.1
ENST00000357896.3
intraflagellar transport 20 homolog (Chlamydomonas)
chr19_+_7049332 0.26 ENST00000381393.3
methyl-CpG binding domain protein 3-like 2
chr7_+_134576317 0.26 ENST00000424922.1
ENST00000495522.1
caldesmon 1
chr17_-_19281203 0.26 ENST00000487415.2
B9 protein domain 1
chr17_+_34431212 0.26 ENST00000394495.1
chemokine (C-C motif) ligand 4
chrX_+_16804544 0.25 ENST00000380122.5
ENST00000398155.4
taxilin gamma
chr3_-_52443799 0.24 ENST00000470173.1
ENST00000296288.5
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr20_+_3190006 0.24 ENST00000380113.3
ENST00000455664.2
ENST00000399838.3
inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
chr10_-_97050777 0.23 ENST00000329399.6
PDZ and LIM domain 1
chr1_-_26633067 0.23 ENST00000421827.2
ENST00000374215.1
ENST00000374223.1
ENST00000357089.4
ENST00000535108.1
ENST00000314675.7
ENST00000436301.2
ENST00000423664.1
ENST00000374221.3
UBX domain protein 11
chrX_+_153665248 0.23 ENST00000447750.2
GDP dissociation inhibitor 1
chr7_-_81399411 0.22 ENST00000423064.2
hepatocyte growth factor (hepapoietin A; scatter factor)
chr14_+_95078714 0.22 ENST00000393078.3
ENST00000393080.4
ENST00000467132.1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr12_-_49351228 0.21 ENST00000541959.1
ENST00000447318.2
ADP-ribosylation factor 3
chr17_+_17942684 0.21 ENST00000376345.3
GID complex subunit 4
chr7_-_994302 0.20 ENST00000265846.5
ArfGAP with dual PH domains 1
chr1_+_27648648 0.20 ENST00000374076.4
transmembrane protein 222
chr3_+_195413160 0.20 ENST00000599448.1
long intergenic non-protein coding RNA 969
chr17_+_7533439 0.20 ENST00000441599.2
ENST00000380450.4
ENST00000416273.3
ENST00000575903.1
ENST00000576830.1
ENST00000571153.1
ENST00000575618.1
ENST00000576152.1
sex hormone-binding globulin
chr1_+_27648709 0.19 ENST00000608611.1
ENST00000466759.1
ENST00000464813.1
ENST00000498220.1
transmembrane protein 222
chr12_+_57610562 0.18 ENST00000349394.5
neurexophilin 4
chr12_-_53074182 0.18 ENST00000252244.3
keratin 1
chr12_-_49351303 0.18 ENST00000256682.4
ADP-ribosylation factor 3
chr19_+_11546440 0.18 ENST00000589126.1
ENST00000588269.1
ENST00000587509.1
ENST00000592741.1
ENST00000593101.1
ENST00000587327.1
protein kinase C substrate 80K-H
chr7_-_28220354 0.17 ENST00000283928.5
JAZF zinc finger 1
chr16_-_2314222 0.17 ENST00000566397.1
RNA binding protein S1, serine-rich domain
chr19_+_55281260 0.17 ENST00000336077.6
ENST00000291633.7
killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
chr17_+_34430980 0.17 ENST00000250151.4
chemokine (C-C motif) ligand 4
chr2_+_223162866 0.17 ENST00000295226.1
coiled-coil domain containing 140
chr2_+_108905325 0.16 ENST00000438339.1
ENST00000409880.1
ENST00000437390.2
sulfotransferase family, cytosolic, 1C, member 2
chr1_+_114472222 0.16 ENST00000369558.1
ENST00000369561.4
homeodomain interacting protein kinase 1
chr7_+_110731062 0.16 ENST00000308478.5
ENST00000451085.1
ENST00000422987.3
ENST00000421101.1
leucine rich repeat neuronal 3
chr22_+_35776828 0.16 ENST00000216117.8
heme oxygenase (decycling) 1
chr20_+_32951041 0.16 ENST00000374864.4
itchy E3 ubiquitin protein ligase
chr19_+_11546153 0.16 ENST00000591946.1
ENST00000252455.2
ENST00000412601.1
protein kinase C substrate 80K-H
chr6_+_131958436 0.16 ENST00000357639.3
ENST00000543135.1
ENST00000427148.2
ENST00000358229.5
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr1_+_39456895 0.16 ENST00000432648.3
ENST00000446189.2
ENST00000372984.4
akirin 1
chr5_-_112257914 0.15 ENST00000513339.1
ENST00000545426.1
ENST00000504247.1
receptor accessory protein 5
chr2_+_108905095 0.15 ENST00000251481.6
ENST00000326853.5
sulfotransferase family, cytosolic, 1C, member 2
chr7_-_38370536 0.15 ENST00000390343.2
T cell receptor gamma variable 8
chr5_-_137610300 0.14 ENST00000274721.3
GDNF family receptor alpha 3
chr5_-_137610254 0.14 ENST00000378362.3
GDNF family receptor alpha 3
chr6_+_29079668 0.14 ENST00000377169.1
olfactory receptor, family 2, subfamily J, member 3
chr17_+_34538310 0.14 ENST00000444414.1
ENST00000378350.4
ENST00000389068.5
ENST00000588929.1
ENST00000589079.1
ENST00000589336.1
ENST00000400702.4
ENST00000591167.1
ENST00000586598.1
ENST00000591637.1
ENST00000378352.4
ENST00000358756.5
chemokine (C-C motif) ligand 4-like 1
chr11_-_66112555 0.14 ENST00000425825.2
ENST00000359957.3
breast cancer metastasis suppressor 1
chr10_+_4868460 0.13 ENST00000532248.1
ENST00000345253.5
ENST00000334019.4
aldo-keto reductase family 1, member E2
chr9_-_14722715 0.13 ENST00000380911.3
cerberus 1, DAN family BMP antagonist
chr19_+_55235969 0.13 ENST00000402254.2
ENST00000538269.1
ENST00000541392.1
ENST00000291860.1
ENST00000396284.2
killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3
killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
chr7_-_76255444 0.13 ENST00000454397.1
POM121 and ZP3 fusion
chr1_+_92417716 0.13 ENST00000402388.1
bromodomain, testis-specific
chr2_+_233320827 0.13 ENST00000295463.3
alkaline phosphatase, intestinal
chr6_-_26124138 0.12 ENST00000314332.5
ENST00000396984.1
histone cluster 1, H2bc
chr19_+_11546093 0.12 ENST00000591462.1
protein kinase C substrate 80K-H
chr17_-_74533734 0.12 ENST00000589342.1
cytoglobin
chr1_+_89150245 0.11 ENST00000370513.5
protein kinase N2
chr1_-_24126051 0.11 ENST00000445705.1
UDP-galactose-4-epimerase
chr5_+_17444119 0.11 ENST00000503267.1
ENST00000504998.1
RP11-321E2.4
chr3_-_52002403 0.11 ENST00000490063.1
ENST00000468324.1
ENST00000497653.1
ENST00000484633.1
poly(rC) binding protein 4
chr4_+_26322409 0.11 ENST00000514807.1
ENST00000348160.4
ENST00000509158.1
ENST00000355476.3
recombination signal binding protein for immunoglobulin kappa J region
chr9_+_36572851 0.11 ENST00000298048.2
ENST00000538311.1
ENST00000536987.1
ENST00000545008.1
ENST00000536860.1
ENST00000536329.1
ENST00000541717.1
ENST00000543751.1
maternal embryonic leucine zipper kinase
chr9_-_117150303 0.11 ENST00000312033.3
AT-hook transcription factor
chr1_+_35225339 0.11 ENST00000339480.1
gap junction protein, beta 4, 30.3kDa
chr21_+_19617140 0.11 ENST00000299295.2
ENST00000338326.3
chondrolectin
chr5_+_50678921 0.11 ENST00000230658.7
ISL LIM homeobox 1
chr12_-_6961050 0.10 ENST00000538862.2
cell division cycle associated 3
chr3_+_133502877 0.10 ENST00000466490.2
signal recognition particle receptor, B subunit
chr7_+_107110488 0.10 ENST00000304402.4
G protein-coupled receptor 22
chr10_-_79789291 0.10 ENST00000372371.3
polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
chr6_+_24126350 0.09 ENST00000378491.4
ENST00000378478.1
ENST00000378477.2
neurensin 1
chr20_+_1115821 0.09 ENST00000435720.1
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr1_-_24126023 0.09 ENST00000429356.1
UDP-galactose-4-epimerase
chr1_+_78245303 0.09 ENST00000370791.3
ENST00000443751.2
family with sequence similarity 73, member A
chr4_+_123300664 0.09 ENST00000388725.2
adenosine deaminase domain containing 1 (testis-specific)
chr13_-_39564993 0.09 ENST00000423210.1
stomatin (EPB72)-like 3
chr17_+_34640031 0.09 ENST00000339270.6
ENST00000482104.1
chemokine (C-C motif) ligand 4-like 2
chr4_+_26322185 0.08 ENST00000361572.6
recombination signal binding protein for immunoglobulin kappa J region
chr3_+_14058794 0.08 ENST00000424053.1
ENST00000528067.1
ENST00000429201.1
tetra-peptide repeat homeobox-like
chr4_+_128554081 0.08 ENST00000335251.6
ENST00000296461.5
inturned planar cell polarity protein
chr5_-_131330272 0.08 ENST00000379240.1
acyl-CoA synthetase long-chain family member 6
chr2_+_166152283 0.08 ENST00000375427.2
sodium channel, voltage-gated, type II, alpha subunit
chr12_-_69326940 0.07 ENST00000549781.1
ENST00000548262.1
ENST00000551568.1
ENST00000548954.1
carboxypeptidase M
chr21_-_45078019 0.07 ENST00000542962.1
heat shock transcription factor 2 binding protein
chr3_+_167453493 0.07 ENST00000295777.5
ENST00000472747.2
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr5_+_140557371 0.07 ENST00000239444.2
protocadherin beta 8
chr1_+_114471972 0.07 ENST00000369559.4
ENST00000369554.2
homeodomain interacting protein kinase 1
chr10_-_115423792 0.07 ENST00000369360.3
ENST00000360478.3
ENST00000359988.3
ENST00000369358.4
nebulin-related anchoring protein
chr7_-_81399329 0.07 ENST00000453411.1
ENST00000444829.2
hepatocyte growth factor (hepapoietin A; scatter factor)
chr12_+_65672702 0.06 ENST00000538045.1
ENST00000535239.1
methionine sulfoxide reductase B3
chr1_+_203765437 0.06 ENST00000550078.1
zinc finger, BED-type containing 6
chr17_+_34639793 0.06 ENST00000394465.2
ENST00000394463.2
ENST00000378342.4
chemokine (C-C motif) ligand 4-like 2
chr7_+_117864815 0.06 ENST00000433239.1
ankyrin repeat domain 7
chr8_+_7801144 0.06 ENST00000443676.1
zinc finger protein 705B
chr7_-_87849340 0.06 ENST00000419179.1
ENST00000265729.2
sorcin
chr20_-_1309809 0.06 ENST00000360779.3
syndecan binding protein (syntenin) 2
chr2_+_122494676 0.06 ENST00000455432.1
translin
chr17_+_57970469 0.06 ENST00000443572.2
ENST00000406116.3
ENST00000225577.4
ENST00000393021.3
ribosomal protein S6 kinase, 70kDa, polypeptide 1
chr22_-_41215291 0.06 ENST00000542412.1
ENST00000544408.1
solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
chr18_-_77276057 0.05 ENST00000597412.1
Uncharacterized protein
chr15_-_34502197 0.05 ENST00000557877.1
katanin p80 subunit B-like 1
chr7_-_81399438 0.05 ENST00000222390.5
hepatocyte growth factor (hepapoietin A; scatter factor)
chr8_-_141810634 0.05 ENST00000521986.1
ENST00000523539.1
ENST00000538769.1
protein tyrosine kinase 2
chr15_-_83474806 0.05 ENST00000541889.1
ENST00000334574.8
ENST00000561368.1
fibronectin type III and SPRY domain containing 2
chr20_+_1093891 0.05 ENST00000333082.3
ENST00000381898.4
ENST00000381899.4
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr6_+_159290917 0.05 ENST00000367072.1
chromosome 6 open reading frame 99
chr5_-_131329918 0.05 ENST00000357096.1
ENST00000431707.1
ENST00000434099.1
acyl-CoA synthetase long-chain family member 6
chr11_-_44972476 0.05 ENST00000527685.1
ENST00000308212.5
tumor protein p53 inducible protein 11
chr5_+_139554227 0.05 ENST00000261811.4
cysteine-rich transmembrane module containing 1
chr1_-_204135450 0.04 ENST00000272190.8
ENST00000367195.2
renin
chr19_+_3721719 0.04 ENST00000589378.1
ENST00000382008.3
tight junction protein 3
chr4_-_69817481 0.04 ENST00000251566.4
UDP glucuronosyltransferase 2 family, polypeptide A3
chr6_-_29013017 0.04 ENST00000377175.1
olfactory receptor, family 2, subfamily W, member 1
chr12_+_128399965 0.04 ENST00000540882.1
ENST00000542089.1
long intergenic non-protein coding RNA 507
chr19_-_18366182 0.04 ENST00000355502.3
phosphodiesterase 4C, cAMP-specific
chr10_+_51565188 0.04 ENST00000430396.2
ENST00000374087.4
ENST00000414907.2
nuclear receptor coactivator 4
chr13_+_24144509 0.04 ENST00000248484.4
tumor necrosis factor receptor superfamily, member 19
chr2_+_133874577 0.04 ENST00000596384.1
HCG2006742; Protein LOC100996685
chr1_-_156542328 0.04 ENST00000361170.2
IQ motif containing GTPase activating protein 3
chr7_+_117864708 0.03 ENST00000357099.4
ENST00000265224.4
ENST00000486422.1
ENST00000417525.1
ankyrin repeat domain 7
chr11_-_61197187 0.03 ENST00000449811.1
ENST00000413232.1
ENST00000340437.4
ENST00000539952.1
ENST00000544585.1
ENST00000450000.1
cleavage and polyadenylation specific factor 7, 59kDa
chr17_-_56084578 0.03 ENST00000582730.2
ENST00000584773.1
ENST00000585096.1
ENST00000258962.4
serine/arginine-rich splicing factor 1
chr4_-_73434498 0.03 ENST00000286657.4
ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr16_+_72459838 0.03 ENST00000564508.1
AC004158.3
chr3_-_133614597 0.03 ENST00000285208.4
ENST00000460865.3
RAB6B, member RAS oncogene family
chr14_-_107211459 0.03 ENST00000390636.2
immunoglobulin heavy variable 3-73
chrX_+_79591003 0.03 ENST00000538312.1
family with sequence similarity 46, member D
chr7_-_229557 0.02 ENST00000514988.1
Uncharacterized protein
chr16_+_69221028 0.02 ENST00000336278.4
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr7_-_752577 0.02 ENST00000544935.1
ENST00000430040.1
ENST00000456696.2
ENST00000406797.1
protein kinase, cAMP-dependent, regulatory, type I, beta
chr22_-_36031181 0.02 ENST00000594060.1
AL049747.1
chr15_-_83621435 0.02 ENST00000450735.2
ENST00000426485.1
ENST00000399166.2
ENST00000304231.8
homer homolog 2 (Drosophila)
chr2_-_85636928 0.02 ENST00000449030.1
capping protein (actin filament), gelsolin-like
chr11_+_133938955 0.02 ENST00000534549.1
ENST00000441717.3
junctional adhesion molecule 3
chr3_-_57678772 0.02 ENST00000311128.5
DENN/MADD domain containing 6A
chr1_+_101702417 0.02 ENST00000305352.6
sphingosine-1-phosphate receptor 1
chr8_-_114449112 0.02 ENST00000455883.2
ENST00000352409.3
ENST00000297405.5
CUB and Sushi multiple domains 3
chr20_+_34129770 0.02 ENST00000348547.2
ENST00000357394.4
ENST00000447986.1
ENST00000279052.6
ENST00000416206.1
ENST00000411577.1
ENST00000413587.1
ERGIC and golgi 3
chr4_-_186456652 0.02 ENST00000284767.5
ENST00000284770.5
PDZ and LIM domain 3
chr1_+_33219592 0.02 ENST00000373481.3
KIAA1522
chr15_-_81195510 0.02 ENST00000561295.1
Uncharacterized protein
chr16_-_88717423 0.02 ENST00000568278.1
ENST00000569359.1
ENST00000567174.1
cytochrome b-245, alpha polypeptide
chr3_+_102153859 0.02 ENST00000306176.1
ENST00000466937.1
zona pellucida-like domain containing 1
chr3_+_38307293 0.01 ENST00000311856.4
solute carrier family 22 (organic anion/urate transporter), member 13
chr14_-_69619689 0.01 ENST00000389997.6
ENST00000557386.1
ENST00000554681.1
DDB1 and CUL4 associated factor 5
chr4_-_186456766 0.01 ENST00000284771.6
PDZ and LIM domain 3
chr12_-_6960407 0.01 ENST00000540683.1
ENST00000229265.6
ENST00000535406.1
ENST00000422785.3
cell division cycle associated 3
chr11_+_133938820 0.01 ENST00000299106.4
ENST00000529443.2
junctional adhesion molecule 3
chr5_+_85913721 0.01 ENST00000247655.3
ENST00000509578.1
ENST00000515763.1
cytochrome c oxidase subunit VIIc
chr4_-_140005443 0.01 ENST00000510408.1
ENST00000420916.2
ENST00000358635.3
E74-like factor 2 (ets domain transcription factor)
chr4_-_151936865 0.00 ENST00000535741.1
LPS-responsive vesicle trafficking, beach and anchor containing
chr12_-_56709674 0.00 ENST00000551286.1
ENST00000549318.1
canopy FGF signaling regulator 2
Uncharacterized protein
chr6_-_106773291 0.00 ENST00000343245.3
autophagy related 5
chr12_+_128399917 0.00 ENST00000544645.1
long intergenic non-protein coding RNA 507
chr12_-_52867569 0.00 ENST00000252250.6
keratin 6C
chr1_-_204165610 0.00 ENST00000367194.4
KiSS-1 metastasis-suppressor

Network of associatons between targets according to the STRING database.

First level regulatory network of T

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.3 1.0 GO:0001798 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.3 1.1 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.2 0.7 GO:0039019 pronephric nephron development(GO:0039019)
0.2 0.8 GO:0032474 otolith morphogenesis(GO:0032474)
0.1 0.3 GO:0007412 axon target recognition(GO:0007412)
0.1 0.5 GO:0035519 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913) protein K29-linked ubiquitination(GO:0035519)
0.1 0.8 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.1 0.4 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.1 0.2 GO:0002731 negative regulation of dendritic cell cytokine production(GO:0002731) FasL biosynthetic process(GO:0045210)
0.1 0.5 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1 0.4 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.2 GO:1901189 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.1 0.2 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1 0.4 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1 0.4 GO:0051342 regulation of cyclic nucleotide catabolic process(GO:0030805) regulation of cAMP catabolic process(GO:0030820) regulation of purine nucleotide catabolic process(GO:0033121) regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.1 0.5 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 0.2 GO:0032764 heme oxidation(GO:0006788) smooth muscle hyperplasia(GO:0014806) negative regulation of mast cell cytokine production(GO:0032764)
0.1 0.2 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 0.1 GO:0071655 granulocyte colony-stimulating factor production(GO:0071611) regulation of granulocyte colony-stimulating factor production(GO:0071655)
0.0 0.1 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.0 0.1 GO:0001207 histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.0 0.3 GO:1902947 regulation of tau-protein kinase activity(GO:1902947)
0.0 0.9 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.4 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.0 0.8 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.2 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.2 GO:0009146 purine nucleoside triphosphate catabolic process(GO:0009146)
0.0 0.6 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.6 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.1 GO:0035803 egg coat formation(GO:0035803)
0.0 0.1 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.1 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.5 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 1.1 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.3 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
0.0 0.2 GO:0002767 immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.0 0.5 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.3 GO:0098779 mitophagy in response to mitochondrial depolarization(GO:0098779)
0.0 0.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.2 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.1 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.3 GO:0051923 sulfation(GO:0051923)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:1902636 kinociliary basal body(GO:1902636)
0.1 1.1 GO:0071438 invadopodium membrane(GO:0071438)
0.1 0.5 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.2 GO:0061574 ASAP complex(GO:0061574)
0.0 0.3 GO:0030478 actin cap(GO:0030478)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 0.1 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 1.2 GO:0035578 azurophil granule lumen(GO:0035578)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.3 1.3 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.1 0.5 GO:0002046 opsin binding(GO:0002046)
0.1 0.4 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 0.8 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.1 0.4 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.4 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.1 0.4 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 0.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 0.2 GO:0003978 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.0 0.7 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.1 GO:0050571 1,5-anhydro-D-fructose reductase activity(GO:0050571)
0.0 0.5 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.7 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.5 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 0.3 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.2 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.1 GO:0030109 HLA-B specific inhibitory MHC class I receptor activity(GO:0030109)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.4 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0016015 morphogen activity(GO:0016015)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 0.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.1 GO:0000150 recombinase activity(GO:0000150)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.1 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.7 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.2 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 1.3 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.2 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.4 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.8 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 1.1 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.5 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.4 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 1.3 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.3 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR