Project
Inflammatory response time course, HUVEC (Wada et al., 2009)
Navigation
Downloads
Results for TAF1
Z-value: 1.67
Motif logo
Transcription factors associated with TAF1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| TAF1 | hg19_v2_chrX_+_70586082_70586114 | 0.87 | 1.7e-08 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chrX_-_62571187 Show fit | 5.51 |
ENST00000335144.3
|
spindlin family, member 4 |
|
| chr17_+_47865917 Show fit | 5.23 |
ENST00000259021.4
ENST00000454930.2 ENST00000509773.1 ENST00000510819.1 ENST00000424009.2 |
K(lysine) acetyltransferase 7 |
|
| chrX_-_62571220 Show fit | 4.54 |
ENST00000374884.2
|
spindlin family, member 4 |
|
| chr12_+_82752275 Show fit | 4.04 |
ENST00000248306.3
|
methyltransferase like 25 |
|
| chr14_-_91526462 Show fit | 3.44 |
ENST00000536315.2
|
ribosomal protein S6 kinase, 90kDa, polypeptide 5 |
|
| chrX_+_153237740 Show fit | 3.22 |
ENST00000369982.4
|
transmembrane protein 187 |
|
| chr12_+_20522179 Show fit | 2.87 |
ENST00000359062.3
|
phosphodiesterase 3A, cGMP-inhibited |
|
| chr12_-_6772303 Show fit | 2.78 |
ENST00000396807.4
ENST00000446105.2 ENST00000341550.4 |
inhibitor of growth family, member 4 |
|
| chr13_-_113242439 Show fit | 2.74 |
ENST00000375669.3
ENST00000261965.3 |
tubulin, gamma complex associated protein 3 |
|
| chr2_-_44588679 Show fit | 2.66 |
ENST00000409411.1
|
prolyl endopeptidase-like |
Network of associatons between targets according to the STRING database.
First level regulatory network of TAF1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 11.5 | GO:2000300 | regulation of synaptic vesicle exocytosis(GO:2000300) |
| 2.0 | 7.9 | GO:0043983 | histone H4-K12 acetylation(GO:0043983) |
| 0.1 | 6.2 | GO:0019985 | translesion synthesis(GO:0019985) |
| 1.0 | 5.1 | GO:0043988 | histone H3-S28 phosphorylation(GO:0043988) |
| 0.3 | 4.9 | GO:0070914 | UV-damage excision repair(GO:0070914) |
| 0.1 | 4.4 | GO:0042407 | cristae formation(GO:0042407) |
| 0.4 | 4.2 | GO:0046477 | glycosylceramide catabolic process(GO:0046477) |
| 0.4 | 3.9 | GO:0006552 | leucine catabolic process(GO:0006552) |
| 0.3 | 3.8 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
| 0.1 | 3.8 | GO:0034453 | microtubule anchoring(GO:0034453) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 6.2 | GO:0000145 | exocyst(GO:0000145) |
| 0.7 | 5.5 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 0.1 | 5.2 | GO:0016591 | DNA-directed RNA polymerase II, holoenzyme(GO:0016591) |
| 0.0 | 5.1 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.4 | 3.5 | GO:0030062 | mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062) |
| 0.1 | 3.4 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.0 | 3.4 | GO:0005778 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
| 0.3 | 3.3 | GO:0044666 | MLL3/4 complex(GO:0044666) |
| 0.2 | 3.2 | GO:0036038 | MKS complex(GO:0036038) |
| 0.0 | 3.1 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 9.3 | GO:0070008 | serine-type exopeptidase activity(GO:0070008) |
| 0.0 | 5.5 | GO:0001158 | enhancer sequence-specific DNA binding(GO:0001158) |
| 0.0 | 5.2 | GO:0000287 | magnesium ion binding(GO:0000287) |
| 0.3 | 4.8 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.1 | 4.2 | GO:0004407 | histone deacetylase activity(GO:0004407) |
| 0.0 | 4.0 | GO:0035064 | methylated histone binding(GO:0035064) |
| 0.0 | 4.0 | GO:0008094 | DNA-dependent ATPase activity(GO:0008094) |
| 0.1 | 3.8 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
| 0.0 | 3.8 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.3 | 3.7 | GO:0004300 | enoyl-CoA hydratase activity(GO:0004300) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 11.6 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
| 0.2 | 5.2 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
| 0.0 | 4.6 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.0 | 4.3 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.1 | 4.0 | PID IGF1 PATHWAY | IGF1 pathway |
| 0.0 | 3.6 | PID AP1 PATHWAY | AP-1 transcription factor network |
| 0.1 | 3.1 | PID INSULIN PATHWAY | Insulin Pathway |
| 0.0 | 3.1 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.1 | 2.9 | PID IL12 STAT4 PATHWAY | IL12 signaling mediated by STAT4 |
| 0.1 | 2.5 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 8.8 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.1 | 5.7 | REACTOME RECYCLING PATHWAY OF L1 | Genes involved in Recycling pathway of L1 |
| 0.1 | 5.0 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.1 | 4.7 | REACTOME SPHINGOLIPID METABOLISM | Genes involved in Sphingolipid metabolism |
| 0.0 | 4.4 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.1 | 4.3 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.1 | 3.6 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.2 | 3.5 | REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 0.1 | 3.4 | REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
| 0.1 | 3.1 | REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |