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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for TBX2

Z-value: 0.71

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Transcription factors associated with TBX2

Gene Symbol Gene ID Gene Info
TBX2
ENSG00000121068.9 T-box transcription factor 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBX2hg19_v2_chr17_+_59477233_594772630.376.7e-02Click!

Activity profile of TBX2 motif

Sorted Z-values of TBX2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_100111580 5.57 ENST00000605497.1
PALMD
palmdelphin
chr1_+_100111479 4.55 ENST00000263174.4
PALMD
palmdelphin
chr4_-_186732048 3.18 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
SORBS2
sorbin and SH3 domain containing 2
chr1_-_100231349 2.76 ENST00000287474.5
ENST00000414213.1
FRRS1
ferric-chelate reductase 1
chr10_-_131762105 2.13 ENST00000368648.3
ENST00000355311.5
EBF3
early B-cell factor 3
chr17_-_34122596 1.83 ENST00000250144.8
MMP28
matrix metallopeptidase 28
chr9_+_40028620 1.82 ENST00000426179.1
AL353791.1
AL353791.1
chr2_-_191878874 1.72 ENST00000392322.3
ENST00000392323.2
ENST00000424722.1
ENST00000361099.3
STAT1
signal transducer and activator of transcription 1, 91kDa
chr12_+_53443963 1.66 ENST00000546602.1
ENST00000552570.1
ENST00000549700.1
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr2_+_189156586 1.55 ENST00000409830.1
GULP1
GULP, engulfment adaptor PTB domain containing 1
chr9_+_2157655 1.53 ENST00000452193.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr1_+_61547894 1.47 ENST00000403491.3
NFIA
nuclear factor I/A
chr4_-_90757364 1.47 ENST00000508895.1
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr4_-_90756769 1.42 ENST00000345009.4
ENST00000505199.1
ENST00000502987.1
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr12_-_7848364 1.40 ENST00000329913.3
GDF3
growth differentiation factor 3
chr12_+_93965609 1.38 ENST00000549887.1
ENST00000551556.1
SOCS2
suppressor of cytokine signaling 2
chr4_+_38511367 1.35 ENST00000507056.1
RP11-213G21.1
RP11-213G21.1
chr1_+_76540386 1.33 ENST00000328299.3
ST6GALNAC3
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr12_+_19358228 1.31 ENST00000424268.1
ENST00000543806.1
PLEKHA5
pleckstrin homology domain containing, family A member 5
chr10_-_7513904 1.22 ENST00000420395.1
RP5-1031D4.2
RP5-1031D4.2
chr21_-_31869451 1.21 ENST00000334058.2
KRTAP19-4
keratin associated protein 19-4
chrX_-_119709637 1.18 ENST00000404115.3
CUL4B
cullin 4B
chr8_+_1993173 0.97 ENST00000523438.1
MYOM2
myomesin 2
chr12_-_107380910 0.93 ENST00000392830.2
ENST00000240050.4
MTERFD3
MTERF domain containing 3
chr2_-_75796837 0.93 ENST00000233712.1
EVA1A
eva-1 homolog A (C. elegans)
chr16_-_67450325 0.92 ENST00000348579.2
ZDHHC1
zinc finger, DHHC-type containing 1
chr19_-_13213662 0.92 ENST00000264824.4
LYL1
lymphoblastic leukemia derived sequence 1
chr8_-_17533838 0.91 ENST00000400046.1
MTUS1
microtubule associated tumor suppressor 1
chr22_+_40441456 0.90 ENST00000402203.1
TNRC6B
trinucleotide repeat containing 6B
chr18_-_52969844 0.90 ENST00000561831.3
TCF4
transcription factor 4
chr4_-_90759440 0.87 ENST00000336904.3
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr1_-_28969517 0.86 ENST00000263974.4
ENST00000373824.4
TAF12
TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
chr8_-_19459993 0.86 ENST00000454498.2
ENST00000520003.1
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr6_-_110500905 0.84 ENST00000392587.2
WASF1
WAS protein family, member 1
chr15_-_52483566 0.83 ENST00000261837.7
GNB5
guanine nucleotide binding protein (G protein), beta 5
chr9_+_90112117 0.83 ENST00000358077.5
DAPK1
death-associated protein kinase 1
chr10_+_54074033 0.82 ENST00000373970.3
DKK1
dickkopf WNT signaling pathway inhibitor 1
chr7_+_114562172 0.80 ENST00000393486.1
ENST00000257724.3
MDFIC
MyoD family inhibitor domain containing
chr3_+_25469802 0.80 ENST00000330688.4
RARB
retinoic acid receptor, beta
chr12_-_57443886 0.80 ENST00000300119.3
MYO1A
myosin IA
chr16_+_640201 0.79 ENST00000563109.1
RAB40C
RAB40C, member RAS oncogene family
chr1_+_2036149 0.77 ENST00000482686.1
ENST00000400920.1
ENST00000486681.1
PRKCZ
protein kinase C, zeta
chr2_-_209118974 0.77 ENST00000415913.1
ENST00000415282.1
ENST00000446179.1
IDH1
isocitrate dehydrogenase 1 (NADP+), soluble
chr11_+_123986069 0.76 ENST00000456829.2
ENST00000361352.5
ENST00000449321.1
ENST00000392748.1
ENST00000360334.4
ENST00000392744.4
VWA5A
von Willebrand factor A domain containing 5A
chr2_+_33701286 0.76 ENST00000403687.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr5_+_140571902 0.75 ENST00000239446.4
PCDHB10
protocadherin beta 10
chr5_-_9630463 0.74 ENST00000382492.2
TAS2R1
taste receptor, type 2, member 1
chr1_-_15735925 0.73 ENST00000427824.1
RP3-467K16.4
RP3-467K16.4
chr7_+_107220899 0.73 ENST00000379117.2
ENST00000473124.1
BCAP29
B-cell receptor-associated protein 29
chr1_+_185703513 0.73 ENST00000271588.4
ENST00000367492.2
HMCN1
hemicentin 1
chr21_-_31859755 0.72 ENST00000334055.3
KRTAP19-2
keratin associated protein 19-2
chr2_-_39664405 0.72 ENST00000341681.5
ENST00000263881.3
MAP4K3
mitogen-activated protein kinase kinase kinase kinase 3
chrX_-_10645773 0.70 ENST00000453318.2
MID1
midline 1 (Opitz/BBB syndrome)
chr17_-_39968406 0.69 ENST00000393928.1
LEPREL4
leprecan-like 4
chr1_+_89829610 0.69 ENST00000370456.4
ENST00000535065.1
GBP6
guanylate binding protein family, member 6
chr10_+_94833642 0.69 ENST00000224356.4
ENST00000394139.1
CYP26A1
cytochrome P450, family 26, subfamily A, polypeptide 1
chr1_-_211752073 0.68 ENST00000367001.4
SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr1_+_38022513 0.66 ENST00000296218.7
DNALI1
dynein, axonemal, light intermediate chain 1
chr22_-_32860427 0.65 ENST00000534972.1
ENST00000397450.1
ENST00000397452.1
BPIFC
BPI fold containing family C
chr8_+_96037205 0.65 ENST00000396124.4
NDUFAF6
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr8_-_124428569 0.64 ENST00000521903.1
ATAD2
ATPase family, AAA domain containing 2
chr12_-_107380846 0.64 ENST00000548101.1
ENST00000550496.1
ENST00000552029.1
MTERFD3
MTERF domain containing 3
chr6_-_41888843 0.64 ENST00000434077.1
ENST00000409312.1
MED20
mediator complex subunit 20
chr3_+_25469724 0.63 ENST00000437042.2
RARB
retinoic acid receptor, beta
chr7_+_107220660 0.62 ENST00000465919.1
ENST00000445771.2
ENST00000479917.1
ENST00000421217.1
ENST00000457837.1
BCAP29
B-cell receptor-associated protein 29
chr3_-_105588231 0.62 ENST00000545639.1
ENST00000394027.3
ENST00000438603.1
ENST00000447441.1
ENST00000443752.1
CBLB
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr4_-_4249924 0.61 ENST00000254742.2
ENST00000382753.4
ENST00000540397.1
ENST00000538516.1
TMEM128
transmembrane protein 128
chr17_+_35849937 0.61 ENST00000394389.4
DUSP14
dual specificity phosphatase 14
chr6_-_84937314 0.60 ENST00000257766.4
ENST00000403245.3
KIAA1009
KIAA1009
chr22_+_38201114 0.60 ENST00000340857.2
H1F0
H1 histone family, member 0
chr3_+_14860831 0.59 ENST00000543601.1
FGD5
FYVE, RhoGEF and PH domain containing 5
chr2_+_120770581 0.59 ENST00000263713.5
EPB41L5
erythrocyte membrane protein band 4.1 like 5
chr7_+_5919458 0.58 ENST00000416608.1
OCM
oncomodulin
chr2_+_87808725 0.57 ENST00000413202.1
LINC00152
long intergenic non-protein coding RNA 152
chr3_+_14860469 0.57 ENST00000285046.5
FGD5
FYVE, RhoGEF and PH domain containing 5
chr11_-_114271139 0.56 ENST00000325636.4
C11orf71
chromosome 11 open reading frame 71
chr2_-_219031709 0.56 ENST00000295683.2
CXCR1
chemokine (C-X-C motif) receptor 1
chr14_+_21467414 0.56 ENST00000554422.1
ENST00000298681.4
SLC39A2
solute carrier family 39 (zinc transporter), member 2
chr12_+_124155652 0.54 ENST00000426174.2
ENST00000303372.5
TCTN2
tectonic family member 2
chr19_-_55458860 0.54 ENST00000592784.1
ENST00000448121.2
ENST00000340844.2
NLRP7
NLR family, pyrin domain containing 7
chr19_-_14628645 0.54 ENST00000598235.1
DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr9_+_124048864 0.53 ENST00000545652.1
GSN
gelsolin
chr15_-_52030293 0.53 ENST00000560491.1
ENST00000267838.3
LYSMD2
LysM, putative peptidoglycan-binding, domain containing 2
chr16_+_12059050 0.53 ENST00000396495.3
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr17_+_58755184 0.52 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
BCAS3
breast carcinoma amplified sequence 3
chr16_+_12058961 0.52 ENST00000053243.1
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr10_-_72142345 0.52 ENST00000373224.1
ENST00000446961.1
ENST00000358141.2
ENST00000357631.2
LRRC20
leucine rich repeat containing 20
chr17_-_60005365 0.52 ENST00000444766.3
INTS2
integrator complex subunit 2
chr8_-_99954788 0.52 ENST00000523601.1
STK3
serine/threonine kinase 3
chr16_-_56553882 0.52 ENST00000568104.1
BBS2
Bardet-Biedl syndrome 2
chr17_-_39968855 0.52 ENST00000355468.3
ENST00000590496.1
LEPREL4
leprecan-like 4
chr6_-_30585009 0.51 ENST00000376511.2
PPP1R10
protein phosphatase 1, regulatory subunit 10
chr2_+_179184955 0.51 ENST00000315022.2
OSBPL6
oxysterol binding protein-like 6
chr8_-_27457494 0.50 ENST00000521770.1
CLU
clusterin
chr5_-_137514333 0.50 ENST00000411594.2
ENST00000430331.1
BRD8
bromodomain containing 8
chr13_-_46543805 0.49 ENST00000378921.2
ZC3H13
zinc finger CCCH-type containing 13
chr12_+_56660633 0.48 ENST00000308197.5
COQ10A
coenzyme Q10 homolog A (S. cerevisiae)
chrX_+_70338366 0.48 ENST00000333646.6
MED12
mediator complex subunit 12
chr14_+_21236586 0.48 ENST00000326783.3
EDDM3B
epididymal protein 3B
chr17_-_8059638 0.48 ENST00000584202.1
ENST00000354903.5
ENST00000577253.1
PER1
period circadian clock 1
chr2_+_1418154 0.48 ENST00000423320.1
ENST00000382198.1
TPO
thyroid peroxidase
chr15_+_25200108 0.48 ENST00000577949.1
ENST00000338094.6
ENST00000338327.4
ENST00000579070.1
ENST00000577565.1
SNURF
SNRPN
SNRPN upstream reading frame protein
small nuclear ribonucleoprotein polypeptide N
chr14_-_100841670 0.47 ENST00000557297.1
ENST00000555813.1
ENST00000557135.1
ENST00000556698.1
ENST00000554509.1
ENST00000555410.1
WARS
tryptophanyl-tRNA synthetase
chr19_-_46526304 0.47 ENST00000008938.4
PGLYRP1
peptidoglycan recognition protein 1
chrX_-_57164058 0.47 ENST00000374906.3
SPIN2A
spindlin family, member 2A
chr2_-_85581701 0.46 ENST00000295802.4
RETSAT
retinol saturase (all-trans-retinol 13,14-reductase)
chr2_+_136343820 0.46 ENST00000410054.1
R3HDM1
R3H domain containing 1
chr15_+_25200074 0.46 ENST00000390687.4
ENST00000584968.1
ENST00000346403.6
ENST00000554227.2
SNRPN
small nuclear ribonucleoprotein polypeptide N
chr1_-_46598371 0.46 ENST00000372006.1
ENST00000425892.1
ENST00000420542.1
ENST00000354242.4
ENST00000340332.6
PIK3R3
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr12_+_32112340 0.46 ENST00000540924.1
ENST00000312561.4
KIAA1551
KIAA1551
chr8_+_1993152 0.44 ENST00000262113.4
MYOM2
myomesin 2
chr8_+_37963311 0.44 ENST00000428278.2
ENST00000521652.1
ASH2L
ash2 (absent, small, or homeotic)-like (Drosophila)
chr5_-_175395283 0.44 ENST00000513482.1
ENST00000265097.4
THOC3
THO complex 3
chr6_+_32132360 0.44 ENST00000333845.6
ENST00000395512.1
ENST00000432129.1
EGFL8
EGF-like-domain, multiple 8
chr17_-_43502987 0.44 ENST00000376922.2
ARHGAP27
Rho GTPase activating protein 27
chr5_-_78281775 0.44 ENST00000396151.3
ENST00000565165.1
ARSB
arylsulfatase B
chr12_+_57853918 0.44 ENST00000532291.1
ENST00000543426.1
ENST00000228682.2
ENST00000546141.1
GLI1
GLI family zinc finger 1
chr14_-_35183755 0.43 ENST00000555765.1
CFL2
cofilin 2 (muscle)
chr16_+_16481306 0.43 ENST00000422673.2
NPIPA7
nuclear pore complex interacting protein family, member A7
chr3_-_183735651 0.42 ENST00000427120.2
ENST00000392579.2
ENST00000382494.2
ENST00000446941.2
ABCC5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr9_-_34662651 0.42 ENST00000259631.4
CCL27
chemokine (C-C motif) ligand 27
chr5_+_71616188 0.42 ENST00000380639.5
ENST00000543322.1
ENST00000503868.1
ENST00000510676.2
ENST00000536805.1
PTCD2
pentatricopeptide repeat domain 2
chr1_-_85930246 0.42 ENST00000426972.3
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr22_-_31328881 0.41 ENST00000445980.1
MORC2
MORC family CW-type zinc finger 2
chr9_-_20622478 0.41 ENST00000355930.6
ENST00000380338.4
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr5_+_64859066 0.41 ENST00000261308.5
ENST00000535264.1
ENST00000538977.1
PPWD1
peptidylprolyl isomerase domain and WD repeat containing 1
chr1_-_22263790 0.41 ENST00000374695.3
HSPG2
heparan sulfate proteoglycan 2
chrX_-_133930285 0.41 ENST00000486347.1
ENST00000343004.5
FAM122B
family with sequence similarity 122B
chrX_+_70338552 0.40 ENST00000374080.3
ENST00000429213.1
MED12
mediator complex subunit 12
chr3_-_112360116 0.40 ENST00000206423.3
ENST00000439685.2
CCDC80
coiled-coil domain containing 80
chr7_-_127032741 0.40 ENST00000393313.1
ENST00000265827.3
ENST00000434602.1
ZNF800
zinc finger protein 800
chr4_-_89619386 0.39 ENST00000323061.5
NAP1L5
nucleosome assembly protein 1-like 5
chr19_+_41119323 0.39 ENST00000599724.1
ENST00000597071.1
ENST00000243562.9
LTBP4
latent transforming growth factor beta binding protein 4
chr7_-_35077653 0.39 ENST00000310974.4
DPY19L1
dpy-19-like 1 (C. elegans)
chr1_+_202172848 0.38 ENST00000255432.7
LGR6
leucine-rich repeat containing G protein-coupled receptor 6
chr12_-_15104040 0.38 ENST00000541644.1
ENST00000545895.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr6_-_13487825 0.38 ENST00000603223.1
GFOD1
glucose-fructose oxidoreductase domain containing 1
chr5_+_154320623 0.38 ENST00000523037.1
ENST00000265229.8
ENST00000439747.3
ENST00000522038.1
MRPL22
mitochondrial ribosomal protein L22
chr2_+_28718921 0.37 ENST00000327757.5
ENST00000422425.2
ENST00000404858.1
PLB1
phospholipase B1
chr7_-_99766191 0.37 ENST00000423751.1
ENST00000360039.4
GAL3ST4
galactose-3-O-sulfotransferase 4
chr19_+_52932435 0.37 ENST00000301085.4
ZNF534
zinc finger protein 534
chr22_-_29138386 0.37 ENST00000544772.1
CHEK2
checkpoint kinase 2
chr11_+_28129795 0.37 ENST00000406787.3
ENST00000342303.5
ENST00000403099.1
ENST00000407364.3
METTL15
methyltransferase like 15
chr1_+_201708992 0.37 ENST00000367295.1
NAV1
neuron navigator 1
chr11_+_12115543 0.36 ENST00000537344.1
ENST00000532179.1
ENST00000526065.1
MICAL2
microtubule associated monooxygenase, calponin and LIM domain containing 2
chr12_-_121019165 0.36 ENST00000341039.2
ENST00000357500.4
POP5
processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae)
chr22_+_23522552 0.36 ENST00000359540.3
ENST00000398512.5
BCR
breakpoint cluster region
chr17_+_38024417 0.36 ENST00000348931.4
ENST00000583811.1
ENST00000584588.1
ENST00000377940.3
ZPBP2
zona pellucida binding protein 2
chr12_-_91348949 0.36 ENST00000358859.2
CCER1
coiled-coil glutamate-rich protein 1
chr9_+_131452239 0.36 ENST00000372688.4
ENST00000372686.5
SET
SET nuclear oncogene
chr16_+_2933229 0.35 ENST00000573965.1
ENST00000572006.1
FLYWCH2
FLYWCH family member 2
chr14_+_103058948 0.35 ENST00000262241.6
RCOR1
REST corepressor 1
chr3_-_61237050 0.34 ENST00000476844.1
ENST00000488467.1
ENST00000492590.1
ENST00000468189.1
FHIT
fragile histidine triad
chr8_+_22857048 0.34 ENST00000251822.6
RHOBTB2
Rho-related BTB domain containing 2
chr13_+_114238997 0.34 ENST00000538138.1
ENST00000375370.5
TFDP1
transcription factor Dp-1
chr11_+_47291645 0.34 ENST00000395336.3
ENST00000402192.2
MADD
MAP-kinase activating death domain
chr6_-_29324054 0.33 ENST00000543825.1
OR5V1
olfactory receptor, family 5, subfamily V, member 1
chr19_-_44405941 0.33 ENST00000587128.1
RP11-15A1.3
RP11-15A1.3
chr5_-_176433350 0.33 ENST00000377227.4
ENST00000377219.2
UIMC1
ubiquitin interaction motif containing 1
chr17_-_7081435 0.32 ENST00000380920.4
ASGR1
asialoglycoprotein receptor 1
chr9_+_134378289 0.32 ENST00000423007.1
ENST00000404875.2
ENST00000441334.1
ENST00000341012.7
ENST00000372228.3
ENST00000402686.3
ENST00000419118.2
ENST00000541219.1
ENST00000354713.4
ENST00000418774.1
ENST00000415075.1
ENST00000448212.1
ENST00000430619.1
POMT1
protein-O-mannosyltransferase 1
chr19_-_41256207 0.32 ENST00000598485.2
ENST00000470681.1
ENST00000339153.3
ENST00000598729.1
C19orf54
chromosome 19 open reading frame 54
chr10_-_5060147 0.32 ENST00000604507.1
AKR1C2
aldo-keto reductase family 1, member C2
chr11_+_20409070 0.32 ENST00000331079.6
PRMT3
protein arginine methyltransferase 3
chr2_+_207139367 0.31 ENST00000374423.3
ZDBF2
zinc finger, DBF-type containing 2
chr17_-_35969409 0.31 ENST00000394378.2
ENST00000585472.1
ENST00000591288.1
ENST00000502449.2
ENST00000345615.4
ENST00000346661.4
ENST00000585689.1
ENST00000339208.6
SYNRG
synergin, gamma
chr15_+_90319557 0.31 ENST00000341735.3
MESP2
mesoderm posterior 2 homolog (mouse)
chr13_-_99630233 0.31 ENST00000376460.1
ENST00000442173.1
DOCK9
dedicator of cytokinesis 9
chr18_+_43684310 0.30 ENST00000592471.1
ENST00000585518.1
HAUS1
HAUS augmin-like complex, subunit 1
chr14_-_23904861 0.30 ENST00000355349.3
MYH7
myosin, heavy chain 7, cardiac muscle, beta
chr16_-_15463926 0.30 ENST00000432570.2
NPIPA5
nuclear pore complex interacting protein family, member A5
chr19_-_36297348 0.30 ENST00000589835.1
PRODH2
proline dehydrogenase (oxidase) 2
chr11_+_86667117 0.30 ENST00000531827.1
RP11-736K20.6
RP11-736K20.6
chr5_-_55290773 0.30 ENST00000502326.3
ENST00000381298.2
IL6ST
interleukin 6 signal transducer (gp130, oncostatin M receptor)
chr13_-_52027134 0.30 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6
integrator complex subunit 6
chr3_+_160117087 0.30 ENST00000357388.3
SMC4
structural maintenance of chromosomes 4
chr19_+_13049413 0.30 ENST00000316448.5
ENST00000588454.1
CALR
calreticulin
chr1_-_46598284 0.30 ENST00000423209.1
ENST00000262741.5
PIK3R3
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr19_+_46000506 0.29 ENST00000396737.2
PPM1N
protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)
chr10_-_101491828 0.29 ENST00000370483.5
ENST00000016171.5
COX15
cytochrome c oxidase assembly homolog 15 (yeast)
chr10_+_45406627 0.29 ENST00000389583.4
TMEM72
transmembrane protein 72
chr2_-_129076151 0.29 ENST00000259241.6
HS6ST1
heparan sulfate 6-O-sulfotransferase 1
chr12_+_1800179 0.28 ENST00000357103.4
ADIPOR2
adiponectin receptor 2
chr11_+_19138670 0.28 ENST00000446113.2
ENST00000399351.3
ZDHHC13
zinc finger, DHHC-type containing 13
chr1_+_47533160 0.28 ENST00000334194.3
CYP4Z1
cytochrome P450, family 4, subfamily Z, polypeptide 1
chr11_-_119252425 0.27 ENST00000260187.2
USP2
ubiquitin specific peptidase 2
chrX_-_106146547 0.27 ENST00000276173.4
ENST00000411805.1
RIPPLY1
ripply transcriptional repressor 1
chr3_+_142315225 0.27 ENST00000457734.2
ENST00000483373.1
ENST00000475296.1
ENST00000495744.1
ENST00000476044.1
ENST00000461644.1
PLS1
plastin 1
chr11_-_236326 0.27 ENST00000525237.1
ENST00000532956.1
ENST00000525319.1
ENST00000524564.1
ENST00000382743.4
SIRT3
sirtuin 3
chr17_-_34195862 0.27 ENST00000592980.1
ENST00000587626.1
C17orf66
chromosome 17 open reading frame 66
chr19_-_51875894 0.27 ENST00000600427.1
ENST00000595217.1
ENST00000221978.5
NKG7
natural killer cell group 7 sequence
chr8_-_67974552 0.27 ENST00000357849.4
COPS5
COP9 signalosome subunit 5
chr7_-_142120321 0.27 ENST00000390377.1
TRBV7-7
T cell receptor beta variable 7-7
chr5_+_150639360 0.27 ENST00000523004.1
GM2A
GM2 ganglioside activator
chr22_-_20367797 0.26 ENST00000424787.2
GGTLC3
gamma-glutamyltransferase light chain 3
chr11_+_1940786 0.26 ENST00000278317.6
ENST00000381561.4
ENST00000381548.3
ENST00000360603.3
ENST00000381549.3
TNNT3
troponin T type 3 (skeletal, fast)
chr17_-_47925379 0.26 ENST00000352793.2
ENST00000334568.4
ENST00000398154.1
ENST00000436235.1
ENST00000326219.5
TAC4
tachykinin 4 (hemokinin)
chr19_-_36001286 0.26 ENST00000602679.1
ENST00000492341.2
ENST00000472252.2
ENST00000602781.1
ENST00000402589.2
ENST00000458071.1
ENST00000436012.1
ENST00000443640.1
ENST00000450261.1
ENST00000467637.1
ENST00000480502.1
ENST00000474928.1
ENST00000414866.2
ENST00000392206.2
ENST00000488892.1
DMKN
dermokine
chr3_+_32726620 0.25 ENST00000331889.6
ENST00000328834.5
CNOT10
CCR4-NOT transcription complex, subunit 10
chr2_-_169769787 0.25 ENST00000451987.1
SPC25
SPC25, NDC80 kinetochore complex component

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.8 GO:1903282 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.4 1.7 GO:0072308 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.4 1.8 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.3 0.8 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.3 0.8 GO:0006097 glyoxylate cycle(GO:0006097)
0.2 0.9 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.2 1.4 GO:0048859 formation of anatomical boundary(GO:0048859)
0.2 0.6 GO:0098758 response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.2 1.4 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.2 0.7 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.2 0.5 GO:0051714 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) positive regulation of cytolysis in other organism(GO:0051714)
0.1 0.6 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.1 0.9 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.1 0.4 GO:0061582 intestinal epithelial cell migration(GO:0061582)
0.1 0.4 GO:0021938 ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.1 1.3 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.4 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.4 GO:0019417 sulfur oxidation(GO:0019417)
0.1 0.4 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.1 0.5 GO:0044858 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.1 1.1 GO:0001955 blood vessel maturation(GO:0001955)
0.1 1.0 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 0.5 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.1 0.7 GO:0097501 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.1 0.8 GO:2000664 positive regulation of interleukin-5 secretion(GO:2000664)
0.1 0.4 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.1 0.5 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 3.2 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.4 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.5 GO:0061517 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.1 0.8 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.4 GO:1990523 bone regeneration(GO:1990523)
0.1 0.3 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
0.1 0.2 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1 0.2 GO:0019858 cytosine metabolic process(GO:0019858)
0.1 1.3 GO:0070914 UV-damage excision repair(GO:0070914)
0.1 1.4 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 0.5 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.1 1.5 GO:0072189 ureter development(GO:0072189)
0.1 0.3 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.1 0.2 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.1 0.2 GO:0032203 telomere formation via telomerase(GO:0032203)
0.1 0.2 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.1 0.7 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.1 0.3 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 0.6 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.1 0.3 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 1.0 GO:0007379 segment specification(GO:0007379)
0.1 0.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.2 GO:0060940 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387) epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.1 0.3 GO:1902896 terminal web assembly(GO:1902896)
0.1 0.3 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.1 0.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 0.3 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 0.3 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.7 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.9 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0 0.4 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.3 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.4 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.1 GO:0039019 pronephric nephron development(GO:0039019)
0.0 0.8 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.0 0.1 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.0 1.3 GO:0006677 glycosylceramide metabolic process(GO:0006677)
0.0 0.3 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.1 GO:0060921 sinoatrial node development(GO:0003163) sinoatrial node cell differentiation(GO:0060921) sinoatrial node cell development(GO:0060931)
0.0 0.2 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.2 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 0.3 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 11.1 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.3 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.3 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.0 0.1 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.0 0.4 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.8 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.5 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.1 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.0 0.3 GO:0046479 ganglioside catabolic process(GO:0006689) glycosphingolipid catabolic process(GO:0046479)
0.0 0.5 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.4 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.0 0.3 GO:0061042 adiponectin-activated signaling pathway(GO:0033211) vascular wound healing(GO:0061042)
0.0 0.2 GO:0044821 nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.3 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 0.3 GO:0016180 snRNA processing(GO:0016180)
0.0 0.5 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.0 0.2 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.0 0.1 GO:0043449 olfactory learning(GO:0008355) cellular alkene metabolic process(GO:0043449)
0.0 0.8 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.0 0.1 GO:0010645 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.0 0.1 GO:0070980 biphenyl catabolic process(GO:0070980)
0.0 0.2 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.0 0.9 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.4 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.7 GO:0030033 microvillus assembly(GO:0030033)
0.0 0.1 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.0 0.2 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.1 GO:0050894 determination of affect(GO:0050894)
0.0 0.7 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.7 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.6 GO:0007635 chemosensory behavior(GO:0007635)
0.0 0.3 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.5 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.1 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.5 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.4 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.1 GO:0003180 aortic valve development(GO:0003176) aortic valve morphogenesis(GO:0003180) notochord formation(GO:0014028)
0.0 0.3 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.3 GO:1903894 regulation of IRE1-mediated unfolded protein response(GO:1903894)
0.0 0.2 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.0 GO:0051586 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.0 0.6 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.3 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.7 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.2 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.0 0.2 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.2 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.2 GO:0009642 response to light intensity(GO:0009642)
0.0 0.0 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.1 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 0.1 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.2 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.3 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 0.6 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.8 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 1.4 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 0.1 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.6 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.8 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.0 0.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.2 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.0 0.1 GO:0061760 antifungal innate immune response(GO:0061760)
0.0 0.1 GO:0002857 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.1 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.1 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.8 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.6 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.5 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.5 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.5 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.2 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.0 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 3.8 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.3 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.1 1.0 GO:0045179 apical cortex(GO:0045179)
0.1 0.7 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 0.5 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.1 0.4 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.1 1.5 GO:0071564 npBAF complex(GO:0071564)
0.1 0.8 GO:0032039 integrator complex(GO:0032039)
0.1 1.6 GO:0032982 myosin filament(GO:0032982)
0.1 0.9 GO:0000124 SAGA complex(GO:0000124)
0.1 0.8 GO:0031209 SCAR complex(GO:0031209)
0.1 0.4 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.2 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 0.8 GO:0005687 U4 snRNP(GO:0005687)
0.0 0.3 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.8 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.3 GO:0031262 Ndc80 complex(GO:0031262)
0.0 1.8 GO:0016592 mediator complex(GO:0016592)
0.0 9.6 GO:0043197 dendritic spine(GO:0043197)
0.0 0.2 GO:1990357 terminal web(GO:1990357)
0.0 0.5 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.5 GO:0030478 actin cap(GO:0030478)
0.0 0.7 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.3 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.3 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 0.3 GO:0000796 condensin complex(GO:0000796)
0.0 0.3 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.8 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.3 GO:0070652 HAUS complex(GO:0070652)
0.0 0.5 GO:0036038 MKS complex(GO:0036038)
0.0 0.1 GO:0097123 cyclin A1-CDK2 complex(GO:0097123)
0.0 0.4 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.2 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.5 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.7 GO:0030315 T-tubule(GO:0030315)
0.0 0.6 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.8 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.6 GO:0070069 cytochrome complex(GO:0070069)
0.0 0.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.8 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.4 GO:0043194 axon initial segment(GO:0043194)
0.0 0.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.1 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.9 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.1 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.6 GO:0097542 ciliary tip(GO:0097542)
0.0 2.3 GO:0030018 Z disc(GO:0030018)
0.0 0.2 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.9 GO:0030286 dynein complex(GO:0030286)
0.0 0.1 GO:0005916 fascia adherens(GO:0005916)
0.0 0.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.3 GO:0032420 stereocilium(GO:0032420)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.2 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.2 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 1.6 GO:0032587 ruffle membrane(GO:0032587)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.8 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.5 2.8 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.3 0.9 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.3 0.8 GO:0051990 isocitrate dehydrogenase (NADP+) activity(GO:0004450) (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.2 1.4 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.2 1.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.2 0.6 GO:0019959 interleukin-8 binding(GO:0019959)
0.2 0.5 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 0.4 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.1 0.7 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.1 0.5 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.1 3.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.3 GO:0019981 interleukin-6 receptor activity(GO:0004915) leukemia inhibitory factor receptor activity(GO:0004923) interleukin-6 binding(GO:0019981)
0.1 0.3 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 0.5 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 0.4 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.1 0.3 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 1.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.5 GO:0004447 iodide peroxidase activity(GO:0004447)
0.1 0.3 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 0.4 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.1 0.9 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.2 GO:0003826 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.1 0.3 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.1 1.1 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 1.0 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.4 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 0.2 GO:0035034 histone acetyltransferase regulator activity(GO:0035034)
0.1 0.3 GO:0047086 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.1 0.7 GO:0039706 co-receptor binding(GO:0039706)
0.1 1.4 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.1 0.2 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.5 GO:0048039 ubiquinone binding(GO:0048039)
0.1 0.3 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.7 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.8 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.2 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.0 0.8 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.6 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.0 0.5 GO:0045159 myosin II binding(GO:0045159)
0.0 0.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.3 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.9 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 1.2 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.6 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.8 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 1.7 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.6 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.2 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.2 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.3 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.8 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.4 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.3 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.6 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.1 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.4 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.4 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.1 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.2 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.1 GO:0031877 somatostatin receptor binding(GO:0031877)
0.0 0.3 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 1.4 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.2 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 0.4 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.2 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.2 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.4 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.9 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.4 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 1.2 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.1 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.1 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.5 GO:0005521 lamin binding(GO:0005521)
0.0 0.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.0 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.0 0.2 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.1 GO:0004913 interleukin-4 receptor activity(GO:0004913)
0.0 0.5 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.5 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.2 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 1.0 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.1 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.6 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.3 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.4 GO:0071949 FAD binding(GO:0071949)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.5 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.5 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.9 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.1 GO:0046625 sphingosine-1-phosphate receptor activity(GO:0038036) sphingolipid binding(GO:0046625)
0.0 0.0 GO:0008184 purine nucleobase binding(GO:0002060) glycogen phosphorylase activity(GO:0008184)
0.0 0.3 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.6 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 1.1 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.1 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.6 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.2 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.5 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.2 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.2 GO:0017166 vinculin binding(GO:0017166)
0.0 0.2 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 3.0 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.1 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.8 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.5 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.0 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.6 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 1.0 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.5 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.8 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.1 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.5 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 1.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.4 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.8 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.8 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.6 PID MYC PATHWAY C-MYC pathway
0.0 0.7 PID ATM PATHWAY ATM pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 1.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 4.6 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 1.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.1 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 1.2 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.5 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.8 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.6 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.4 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.9 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.4 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.5 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.6 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.4 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.6 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.6 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.9 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.6 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.5 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.5 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.1 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.8 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0 0.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.4 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation