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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for TCF7

Z-value: 0.72

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Transcription factors associated with TCF7

Gene Symbol Gene ID Gene Info
TCF7
ENSG00000081059.15 transcription factor 7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TCF7hg19_v2_chr5_+_133451254_1334513160.442.9e-02Click!

Activity profile of TCF7 motif

Sorted Z-values of TCF7 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_29527702 5.30 ENST00000377050.4
UBD
ubiquitin D
chr21_+_26934165 3.73 ENST00000456917.1
MIR155HG
MIR155 host gene (non-protein coding)
chr10_-_49860525 1.98 ENST00000435790.2
ARHGAP22
Rho GTPase activating protein 22
chr15_+_62359175 1.97 ENST00000355522.5
C2CD4A
C2 calcium-dependent domain containing 4A
chr8_-_119964434 1.79 ENST00000297350.4
TNFRSF11B
tumor necrosis factor receptor superfamily, member 11b
chr5_-_16936340 1.77 ENST00000507288.1
ENST00000513610.1
MYO10
myosin X
chr2_+_108994466 1.48 ENST00000272452.2
SULT1C4
sulfotransferase family, cytosolic, 1C, member 4
chr1_+_169079823 1.48 ENST00000367813.3
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr4_-_139163491 1.42 ENST00000280612.5
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr6_+_26383404 1.35 ENST00000416795.2
ENST00000494184.1
BTN2A2
butyrophilin, subfamily 2, member A2
chr2_-_208031542 1.25 ENST00000423015.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr12_+_21654714 1.22 ENST00000542038.1
ENST00000540141.1
ENST00000229314.5
GOLT1B
golgi transport 1B
chr6_+_138188551 1.11 ENST00000237289.4
ENST00000433680.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr8_-_8751068 1.07 ENST00000276282.6
MFHAS1
malignant fibrous histiocytoma amplified sequence 1
chr2_+_26568965 1.02 ENST00000260585.7
ENST00000447170.1
EPT1
ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)
chr6_+_26383318 0.99 ENST00000469230.1
ENST00000490025.1
ENST00000356709.4
ENST00000352867.2
ENST00000493275.1
ENST00000472507.1
ENST00000482536.1
ENST00000432533.2
ENST00000482842.1
BTN2A2
butyrophilin, subfamily 2, member A2
chr12_-_89920030 0.98 ENST00000413530.1
ENST00000547474.1
GALNT4
POC1B-GALNT4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
POC1B-GALNT4 readthrough
chr2_-_208031943 0.98 ENST00000421199.1
ENST00000457962.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr2_-_231989808 0.96 ENST00000258400.3
HTR2B
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chr17_-_63557309 0.93 ENST00000580513.1
AXIN2
axin 2
chr2_+_108994633 0.92 ENST00000409309.3
SULT1C4
sulfotransferase family, cytosolic, 1C, member 4
chr9_+_103189405 0.90 ENST00000395067.2
MSANTD3
Myb/SANT-like DNA-binding domain containing 3
chr11_-_10830463 0.89 ENST00000527419.1
ENST00000530211.1
ENST00000530702.1
ENST00000524932.1
ENST00000532570.1
EIF4G2
eukaryotic translation initiation factor 4 gamma, 2
chr8_+_27629459 0.88 ENST00000523566.1
ESCO2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr17_+_74372662 0.83 ENST00000591651.1
ENST00000545180.1
SPHK1
sphingosine kinase 1
chr14_-_85996332 0.79 ENST00000380722.1
RP11-497E19.1
RP11-497E19.1
chr8_-_90996459 0.78 ENST00000517337.1
ENST00000409330.1
NBN
nibrin
chr17_-_63556414 0.76 ENST00000585045.1
AXIN2
axin 2
chr1_-_209824643 0.74 ENST00000391911.1
ENST00000415782.1
LAMB3
laminin, beta 3
chr19_+_10765699 0.73 ENST00000590009.1
ILF3
interleukin enhancer binding factor 3, 90kDa
chr3_-_190167571 0.70 ENST00000354905.2
TMEM207
transmembrane protein 207
chr15_+_63414760 0.69 ENST00000557972.1
LACTB
lactamase, beta
chr8_-_101962777 0.68 ENST00000395951.3
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr1_+_68150744 0.67 ENST00000370986.4
ENST00000370985.3
GADD45A
growth arrest and DNA-damage-inducible, alpha
chr6_+_83073952 0.67 ENST00000543496.1
TPBG
trophoblast glycoprotein
chr3_-_167813132 0.66 ENST00000309027.4
GOLIM4
golgi integral membrane protein 4
chr1_+_182808474 0.65 ENST00000367549.3
DHX9
DEAH (Asp-Glu-Ala-His) box helicase 9
chr9_+_103189536 0.64 ENST00000374885.1
MSANTD3
Myb/SANT-like DNA-binding domain containing 3
chr1_+_16010779 0.64 ENST00000375799.3
ENST00000375793.2
PLEKHM2
pleckstrin homology domain containing, family M (with RUN domain) member 2
chr8_+_145064215 0.62 ENST00000313269.5
GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr6_-_89927151 0.61 ENST00000454853.2
GABRR1
gamma-aminobutyric acid (GABA) A receptor, rho 1
chr11_-_57092381 0.61 ENST00000358252.3
TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr22_+_30821732 0.60 ENST00000355143.4
MTFP1
mitochondrial fission process 1
chr8_-_12612962 0.58 ENST00000398246.3
LONRF1
LON peptidase N-terminal domain and ring finger 1
chr4_+_95972822 0.58 ENST00000509540.1
ENST00000440890.2
BMPR1B
bone morphogenetic protein receptor, type IB
chr2_+_68870721 0.57 ENST00000303786.3
PROKR1
prokineticin receptor 1
chr6_+_83073334 0.56 ENST00000369750.3
TPBG
trophoblast glycoprotein
chr12_-_49351148 0.56 ENST00000398092.4
ENST00000539611.1
RP11-302B13.5
ARF3
ADP-ribosylation factor 3
ADP-ribosylation factor 3
chr3_+_185431080 0.56 ENST00000296270.1
C3orf65
chromosome 3 open reading frame 65
chr6_-_90062543 0.55 ENST00000435041.2
UBE2J1
ubiquitin-conjugating enzyme E2, J1
chr4_-_23735183 0.55 ENST00000507666.1
RP11-380P13.2
RP11-380P13.2
chr19_+_10765003 0.55 ENST00000407004.3
ENST00000589998.1
ENST00000589600.1
ILF3
interleukin enhancer binding factor 3, 90kDa
chr7_+_134576317 0.55 ENST00000424922.1
ENST00000495522.1
CALD1
caldesmon 1
chr10_+_70847852 0.54 ENST00000242465.3
SRGN
serglycin
chr4_-_120243545 0.53 ENST00000274024.3
FABP2
fatty acid binding protein 2, intestinal
chr15_+_81293254 0.52 ENST00000267984.2
MESDC1
mesoderm development candidate 1
chr2_-_160761179 0.51 ENST00000554112.1
ENST00000553424.1
ENST00000263636.4
ENST00000504764.1
ENST00000505052.1
LY75
LY75-CD302
lymphocyte antigen 75
LY75-CD302 readthrough
chr3_-_197024394 0.50 ENST00000434148.1
ENST00000412364.2
ENST00000436682.1
ENST00000456699.2
ENST00000392380.2
DLG1
discs, large homolog 1 (Drosophila)
chr6_-_11807277 0.50 ENST00000379415.2
ADTRP
androgen-dependent TFPI-regulating protein
chr1_+_955448 0.49 ENST00000379370.2
AGRN
agrin
chr3_+_118865028 0.49 ENST00000460150.1
C3orf30
chromosome 3 open reading frame 30
chr6_+_64281906 0.48 ENST00000370651.3
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr16_+_68678739 0.48 ENST00000264012.4
CDH3
cadherin 3, type 1, P-cadherin (placental)
chr5_+_34757309 0.47 ENST00000397449.1
RAI14
retinoic acid induced 14
chr7_-_19184929 0.46 ENST00000275461.3
FERD3L
Fer3-like bHLH transcription factor
chr19_+_13135386 0.46 ENST00000360105.4
ENST00000588228.1
ENST00000591028.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr12_+_121131970 0.46 ENST00000535656.1
MLEC
malectin
chr8_+_38644778 0.44 ENST00000276520.8
TACC1
transforming, acidic coiled-coil containing protein 1
chr12_+_104359614 0.44 ENST00000266775.9
ENST00000544861.1
TDG
thymine-DNA glycosylase
chr4_-_7069760 0.44 ENST00000264954.4
GRPEL1
GrpE-like 1, mitochondrial (E. coli)
chr3_+_12598563 0.43 ENST00000411987.1
ENST00000448482.1
MKRN2
makorin ring finger protein 2
chr10_+_96522361 0.42 ENST00000371321.3
CYP2C19
cytochrome P450, family 2, subfamily C, polypeptide 19
chr9_-_21368075 0.41 ENST00000449498.1
IFNA13
interferon, alpha 13
chr7_+_55086703 0.41 ENST00000455089.1
ENST00000342916.3
ENST00000344576.2
ENST00000420316.2
EGFR
epidermal growth factor receptor
chr10_+_99332198 0.41 ENST00000307518.5
ENST00000298808.5
ENST00000370655.1
ANKRD2
ankyrin repeat domain 2 (stretch responsive muscle)
chr16_-_81110683 0.41 ENST00000565253.1
ENST00000378611.4
ENST00000299578.5
C16orf46
chromosome 16 open reading frame 46
chr5_-_157002749 0.41 ENST00000517905.1
ENST00000430702.2
ENST00000394020.1
ADAM19
ADAM metallopeptidase domain 19
chr5_-_36301984 0.41 ENST00000502994.1
ENST00000515759.1
ENST00000296604.3
RANBP3L
RAN binding protein 3-like
chr10_+_6622345 0.40 ENST00000445427.1
ENST00000455810.1
PRKCQ-AS1
PRKCQ antisense RNA 1
chr2_+_89184868 0.39 ENST00000390243.2
IGKV4-1
immunoglobulin kappa variable 4-1
chr11_-_85430163 0.39 ENST00000529581.1
ENST00000533577.1
SYTL2
synaptotagmin-like 2
chr11_-_85430204 0.39 ENST00000389958.3
ENST00000527794.1
SYTL2
synaptotagmin-like 2
chr18_-_56296182 0.39 ENST00000361673.3
ALPK2
alpha-kinase 2
chr15_+_73344791 0.39 ENST00000261908.6
NEO1
neogenin 1
chr6_-_62996066 0.39 ENST00000281156.4
KHDRBS2
KH domain containing, RNA binding, signal transduction associated 2
chr5_-_58571935 0.38 ENST00000503258.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr2_+_159651821 0.38 ENST00000309950.3
ENST00000409042.1
DAPL1
death associated protein-like 1
chr3_+_171561127 0.38 ENST00000334567.5
ENST00000450693.1
TMEM212
transmembrane protein 212
chr7_-_80548667 0.38 ENST00000265361.3
SEMA3C
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr11_-_85430088 0.37 ENST00000533057.1
ENST00000533892.1
SYTL2
synaptotagmin-like 2
chr6_+_108881012 0.37 ENST00000343882.6
FOXO3
forkhead box O3
chr14_-_35344093 0.37 ENST00000382422.2
BAZ1A
bromodomain adjacent to zinc finger domain, 1A
chr13_+_29233218 0.36 ENST00000380842.4
POMP
proteasome maturation protein
chr16_-_46865047 0.36 ENST00000394806.2
C16orf87
chromosome 16 open reading frame 87
chr13_+_102142296 0.36 ENST00000376162.3
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr10_-_61513201 0.35 ENST00000414264.1
ENST00000594536.1
LINC00948
long intergenic non-protein coding RNA 948
chr6_+_64282447 0.35 ENST00000370650.2
ENST00000578299.1
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr1_+_244515930 0.34 ENST00000366537.1
ENST00000308105.4
C1orf100
chromosome 1 open reading frame 100
chr1_-_153013588 0.34 ENST00000360379.3
SPRR2D
small proline-rich protein 2D
chr6_-_11779174 0.34 ENST00000379413.2
ADTRP
androgen-dependent TFPI-regulating protein
chr1_-_32801825 0.34 ENST00000329421.7
MARCKSL1
MARCKS-like 1
chr16_+_2198604 0.34 ENST00000210187.6
RAB26
RAB26, member RAS oncogene family
chr21_-_32185570 0.34 ENST00000329621.4
KRTAP8-1
keratin associated protein 8-1
chr4_+_56815102 0.33 ENST00000257287.4
CEP135
centrosomal protein 135kDa
chr12_+_49717081 0.33 ENST00000547807.1
ENST00000551567.1
TROAP
trophinin associated protein
chr2_-_100721923 0.32 ENST00000356421.2
AFF3
AF4/FMR2 family, member 3
chr2_-_231084659 0.32 ENST00000258381.6
ENST00000358662.4
ENST00000455674.1
ENST00000392048.3
SP110
SP110 nuclear body protein
chr5_-_157286104 0.31 ENST00000530742.1
ENST00000523908.1
ENST00000523094.1
ENST00000296951.5
ENST00000411809.2
CLINT1
clathrin interactor 1
chr19_-_56826157 0.31 ENST00000592509.1
ENST00000592679.1
ENST00000588442.1
ENST00000593106.1
ENST00000587492.1
ENST00000254165.3
ZSCAN5A
zinc finger and SCAN domain containing 5A
chr12_-_49582593 0.31 ENST00000295766.5
TUBA1A
tubulin, alpha 1a
chr12_+_108523133 0.31 ENST00000547525.1
WSCD2
WSC domain containing 2
chr12_+_104359641 0.31 ENST00000537100.1
TDG
thymine-DNA glycosylase
chr21_+_33784670 0.30 ENST00000300255.2
EVA1C
eva-1 homolog C (C. elegans)
chrX_+_119292467 0.30 ENST00000371388.3
RHOXF2
Rhox homeobox family, member 2
chr6_+_43457317 0.30 ENST00000438588.2
TJAP1
tight junction associated protein 1 (peripheral)
chr17_-_40337470 0.30 ENST00000293330.1
HCRT
hypocretin (orexin) neuropeptide precursor
chr1_+_10459111 0.30 ENST00000541529.1
ENST00000270776.8
ENST00000483936.1
ENST00000538557.1
PGD
phosphogluconate dehydrogenase
chr12_-_109915098 0.30 ENST00000542858.1
ENST00000542262.1
ENST00000424763.2
KCTD10
potassium channel tetramerization domain containing 10
chr4_-_56458374 0.30 ENST00000295645.4
PDCL2
phosducin-like 2
chr8_+_30244580 0.29 ENST00000523115.1
ENST00000519647.1
RBPMS
RNA binding protein with multiple splicing
chr6_+_159084188 0.29 ENST00000367081.3
SYTL3
synaptotagmin-like 3
chr3_+_169490834 0.28 ENST00000392733.1
MYNN
myoneurin
chr12_+_6309963 0.28 ENST00000382515.2
CD9
CD9 molecule
chr1_-_149900122 0.28 ENST00000271628.8
SF3B4
splicing factor 3b, subunit 4, 49kDa
chr1_-_155948318 0.27 ENST00000361247.4
ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr12_-_133405288 0.27 ENST00000204726.3
GOLGA3
golgin A3
chr20_-_13971255 0.27 ENST00000284951.5
ENST00000378072.5
SEL1L2
sel-1 suppressor of lin-12-like 2 (C. elegans)
chr3_-_108672742 0.27 ENST00000261047.3
GUCA1C
guanylate cyclase activator 1C
chr1_-_200992827 0.27 ENST00000332129.2
ENST00000422435.2
KIF21B
kinesin family member 21B
chr3_-_108672609 0.26 ENST00000393963.3
ENST00000471108.1
GUCA1C
guanylate cyclase activator 1C
chr4_-_109090106 0.26 ENST00000379951.2
LEF1
lymphoid enhancer-binding factor 1
chr19_+_41949054 0.26 ENST00000378187.2
C19orf69
chromosome 19 open reading frame 69
chr4_-_5891918 0.26 ENST00000512574.1
CRMP1
collapsin response mediator protein 1
chr3_+_152879985 0.26 ENST00000323534.2
RAP2B
RAP2B, member of RAS oncogene family
chr16_-_46864955 0.26 ENST00000565112.1
C16orf87
chromosome 16 open reading frame 87
chr12_+_49717019 0.26 ENST00000549275.1
ENST00000551245.1
ENST00000380327.5
ENST00000548311.1
ENST00000550346.1
ENST00000550709.1
ENST00000549534.1
ENST00000257909.3
TROAP
trophinin associated protein
chr1_+_183774240 0.25 ENST00000360851.3
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr4_-_109089573 0.25 ENST00000265165.1
LEF1
lymphoid enhancer-binding factor 1
chrX_+_120181457 0.25 ENST00000328078.1
GLUD2
glutamate dehydrogenase 2
chr19_+_11909329 0.25 ENST00000323169.5
ENST00000450087.1
ZNF491
zinc finger protein 491
chr17_+_79953310 0.25 ENST00000582355.2
ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr7_-_16505440 0.25 ENST00000307068.4
SOSTDC1
sclerostin domain containing 1
chr1_-_153113927 0.25 ENST00000368752.4
SPRR2B
small proline-rich protein 2B
chr3_+_133502877 0.25 ENST00000466490.2
SRPRB
signal recognition particle receptor, B subunit
chr1_-_33502528 0.25 ENST00000354858.6
AK2
adenylate kinase 2
chr19_-_55690758 0.25 ENST00000590851.1
SYT5
synaptotagmin V
chr12_-_133464151 0.24 ENST00000315585.7
ENST00000266880.7
ENST00000443047.2
ENST00000432561.2
ENST00000450056.2
CHFR
checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
chr8_+_77593448 0.24 ENST00000521891.2
ZFHX4
zinc finger homeobox 4
chr12_-_3982511 0.24 ENST00000427057.2
ENST00000228820.4
PARP11
poly (ADP-ribose) polymerase family, member 11
chr10_+_64893039 0.24 ENST00000277746.6
ENST00000435510.2
NRBF2
nuclear receptor binding factor 2
chr9_-_127533519 0.24 ENST00000487099.2
ENST00000344523.4
ENST00000373584.3
NR6A1
nuclear receptor subfamily 6, group A, member 1
chr11_-_65625678 0.24 ENST00000308162.5
CFL1
cofilin 1 (non-muscle)
chr17_-_56565736 0.23 ENST00000323777.3
HSF5
heat shock transcription factor family member 5
chr11_+_113848216 0.23 ENST00000299961.5
HTR3A
5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
chr6_+_116937636 0.23 ENST00000368581.4
ENST00000229554.5
ENST00000368580.4
RSPH4A
radial spoke head 4 homolog A (Chlamydomonas)
chr22_+_39077947 0.22 ENST00000216034.4
TOMM22
translocase of outer mitochondrial membrane 22 homolog (yeast)
chr10_-_69455873 0.22 ENST00000433211.2
CTNNA3
catenin (cadherin-associated protein), alpha 3
chrX_-_55020511 0.22 ENST00000375006.3
ENST00000374992.2
PFKFB1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr7_-_25702669 0.22 ENST00000446840.1
AC003090.1
AC003090.1
chr7_+_134576151 0.22 ENST00000393118.2
CALD1
caldesmon 1
chr12_+_104359576 0.22 ENST00000392872.3
ENST00000436021.2
TDG
thymine-DNA glycosylase
chr5_+_135364584 0.22 ENST00000442011.2
ENST00000305126.8
TGFBI
transforming growth factor, beta-induced, 68kDa
chr3_+_111717511 0.22 ENST00000478951.1
ENST00000393917.2
TAGLN3
transgelin 3
chr3_+_118864991 0.22 ENST00000295622.1
C3orf30
chromosome 3 open reading frame 30
chr6_+_64346386 0.21 ENST00000509330.1
PHF3
PHD finger protein 3
chr19_+_57791419 0.21 ENST00000537645.1
ZNF460
zinc finger protein 460
chr10_-_104211294 0.21 ENST00000239125.1
C10orf95
chromosome 10 open reading frame 95
chr9_+_113431059 0.21 ENST00000416899.2
MUSK
muscle, skeletal, receptor tyrosine kinase
chr3_+_111717600 0.21 ENST00000273368.4
TAGLN3
transgelin 3
chr3_+_12598509 0.21 ENST00000170447.7
MKRN2
makorin ring finger protein 2
chr12_+_93096759 0.21 ENST00000544406.2
C12orf74
chromosome 12 open reading frame 74
chr10_+_52750930 0.20 ENST00000401604.2
PRKG1
protein kinase, cGMP-dependent, type I
chr2_-_166060571 0.20 ENST00000360093.3
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr3_+_178276488 0.20 ENST00000432997.1
ENST00000455865.1
KCNMB2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr8_+_36641842 0.20 ENST00000523973.1
ENST00000399881.3
KCNU1
potassium channel, subfamily U, member 1
chr15_-_73075964 0.20 ENST00000563907.1
ADPGK
ADP-dependent glucokinase
chr19_+_45281118 0.20 ENST00000270279.3
ENST00000341505.4
CBLC
Cbl proto-oncogene C, E3 ubiquitin protein ligase
chr12_+_104697504 0.20 ENST00000527879.1
EID3
EP300 interacting inhibitor of differentiation 3
chr5_+_135170331 0.20 ENST00000425402.1
ENST00000274513.5
ENST00000420621.1
ENST00000433282.2
ENST00000412661.2
SLC25A48
solute carrier family 25, member 48
chr8_-_6914251 0.19 ENST00000330590.2
DEFA5
defensin, alpha 5, Paneth cell-specific
chr11_-_64013288 0.19 ENST00000542235.1
PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr18_+_21572737 0.19 ENST00000304621.6
TTC39C
tetratricopeptide repeat domain 39C
chr3_+_35681081 0.19 ENST00000428373.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr2_+_166326157 0.19 ENST00000421875.1
ENST00000314499.7
ENST00000409664.1
CSRNP3
cysteine-serine-rich nuclear protein 3
chr1_+_244998918 0.19 ENST00000366528.3
COX20
COX20 cytochrome C oxidase assembly factor
chr13_+_30002741 0.19 ENST00000380808.2
MTUS2
microtubule associated tumor suppressor candidate 2
chr7_-_102232891 0.19 ENST00000514917.2
RP11-514P8.7
RP11-514P8.7
chr1_+_9299895 0.19 ENST00000602477.1
H6PD
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr2_-_80531399 0.19 ENST00000409148.1
ENST00000415098.1
ENST00000452811.1
LRRTM1
leucine rich repeat transmembrane neuronal 1
chr11_-_108422926 0.19 ENST00000428840.1
ENST00000526312.1
EXPH5
exophilin 5
chr8_-_145047688 0.18 ENST00000356346.3
PLEC
plectin
chrX_+_38420783 0.18 ENST00000422612.2
ENST00000286824.6
ENST00000545599.1
TSPAN7
tetraspanin 7
chr22_+_29279552 0.18 ENST00000544604.2
ZNRF3
zinc and ring finger 3
chr20_+_5987890 0.18 ENST00000378868.4
CRLS1
cardiolipin synthase 1
chr3_+_36421826 0.18 ENST00000273183.3
STAC
SH3 and cysteine rich domain
chr19_+_57791806 0.18 ENST00000360338.3
ZNF460
zinc finger protein 460
chr3_+_52719936 0.18 ENST00000418458.1
ENST00000394799.2
GNL3
guanine nucleotide binding protein-like 3 (nucleolar)
chr7_-_87505658 0.18 ENST00000341119.5
SLC25A40
solute carrier family 25, member 40
chr2_+_10183651 0.18 ENST00000305883.1
KLF11
Kruppel-like factor 11
chr12_+_69979446 0.18 ENST00000543146.2
CCT2
chaperonin containing TCP1, subunit 2 (beta)

Network of associatons between targets according to the STRING database.

First level regulatory network of TCF7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 5.3 GO:0070842 aggresome assembly(GO:0070842)
0.6 1.8 GO:0042489 negative regulation of odontogenesis of dentin-containing tooth(GO:0042489)
0.6 1.7 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.4 1.1 GO:0071947 B-1 B cell homeostasis(GO:0001922) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947) negative regulation of osteoclast proliferation(GO:0090291)
0.3 1.5 GO:1903281 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281) positive regulation of potassium ion import(GO:1903288)
0.3 0.8 GO:0046521 sphingoid catabolic process(GO:0046521)
0.2 1.0 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.2 0.8 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.2 1.0 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.2 0.5 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.2 0.5 GO:0051796 regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
0.1 0.9 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.7 GO:0035549 positive regulation of interferon-beta secretion(GO:0035549)
0.1 2.3 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 0.4 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.1 0.5 GO:1904398 positive regulation of neuromuscular junction development(GO:1904398)
0.1 0.6 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 0.6 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.1 0.5 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.1 0.4 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.1 0.3 GO:0019521 pentose-phosphate shunt, oxidative branch(GO:0009051) aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
0.1 0.4 GO:0006172 ADP biosynthetic process(GO:0006172)
0.1 1.2 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.1 0.3 GO:1904616 regulation of actin filament binding(GO:1904529) negative regulation of actin filament binding(GO:1904530) regulation of actin binding(GO:1904616) negative regulation of actin binding(GO:1904617)
0.1 2.3 GO:0006068 ethanol catabolic process(GO:0006068)
0.1 0.5 GO:1903286 regulation of potassium ion import(GO:1903286)
0.1 0.6 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.1 0.4 GO:0003350 pulmonary myocardium development(GO:0003350)
0.1 0.1 GO:0060577 pulmonary vein morphogenesis(GO:0060577)
0.1 0.2 GO:0051086 chaperone mediated protein folding independent of cofactor(GO:0051086)
0.1 0.3 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1 1.4 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 0.5 GO:0033504 floor plate development(GO:0033504)
0.1 0.6 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.1 0.3 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.1 0.4 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.1 0.4 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 0.3 GO:0060648 mammary gland bud morphogenesis(GO:0060648) regulation of determination of dorsal identity(GO:2000015)
0.1 0.3 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.7 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.2 GO:0033133 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.4 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.3 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.0 0.1 GO:1904106 protein localization to microvillus(GO:1904106)
0.0 0.1 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 2.5 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.5 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.2 GO:2000051 Wnt receptor catabolic process(GO:0038018) negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.1 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.0 0.7 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.2 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.0 0.1 GO:0071288 cellular response to mercury ion(GO:0071288)
0.0 0.2 GO:0051511 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.1 GO:1903179 regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181) negative regulation of protein catabolic process in the vacuole(GO:1904351) negative regulation of lysosomal protein catabolic process(GO:1905166)
0.0 0.2 GO:1900738 cytolysis in other organism involved in symbiotic interaction(GO:0051801) positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.0 0.2 GO:2001271 regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.9 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.7 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0 0.1 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.0 0.3 GO:0009414 response to water deprivation(GO:0009414)
0.0 0.2 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.0 0.4 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.0 0.1 GO:0071484 response to high light intensity(GO:0009644) cellular response to light intensity(GO:0071484)
0.0 0.2 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.1 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.0 0.2 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.1 GO:0035106 operant conditioning(GO:0035106)
0.0 0.6 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.6 GO:0014850 response to muscle activity(GO:0014850)
0.0 0.2 GO:0097068 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.0 0.1 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.0 0.8 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.3 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.4 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 0.1 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.1 GO:1904693 midbrain morphogenesis(GO:1904693)
0.0 0.1 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0 0.1 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.3 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 1.3 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.1 GO:1900191 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.0 0.0 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.0 0.2 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.1 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.3 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.6 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.2 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.1 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.0 0.2 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)
0.0 0.1 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.1 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.2 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.1 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.1 GO:0034128 negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.0 0.8 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.2 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.2 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.1 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.0 1.0 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.5 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.0 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.0 GO:0072086 specification of loop of Henle identity(GO:0072086) pattern specification involved in metanephros development(GO:0072268)
0.0 0.5 GO:0019228 neuronal action potential(GO:0019228)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 0.4 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.1 0.7 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.4 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.1 0.8 GO:0030870 Mre11 complex(GO:0030870)
0.1 1.5 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 1.8 GO:0032433 filopodium tip(GO:0032433)
0.1 0.2 GO:0001534 radial spoke(GO:0001534)
0.1 5.1 GO:0016235 aggresome(GO:0016235)
0.1 0.5 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 1.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.3 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.2 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.8 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.2 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.5 GO:0043219 lateral loop(GO:0043219)
0.0 0.6 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.1 GO:0035841 new growing cell tip(GO:0035841)
0.0 0.9 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.6 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.0 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.2 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.2 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.5 GO:0042588 zymogen granule(GO:0042588)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.1 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.6 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.4 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 1.7 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)
0.0 0.5 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.6 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.2 GO:0005916 fascia adherens(GO:0005916)
0.0 0.3 GO:0045180 basal cortex(GO:0045180)
0.0 0.5 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.2 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 1.6 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0045179 apical cortex(GO:0045179)
0.0 0.7 GO:0001533 cornified envelope(GO:0001533)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.3 1.4 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.3 5.3 GO:0070628 proteasome binding(GO:0070628)
0.2 0.7 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) DNA/RNA helicase activity(GO:0033677)
0.2 1.8 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 0.8 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.4 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.9 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 2.5 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 1.2 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 0.6 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.1 0.6 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.4 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 1.7 GO:0070411 I-SMAD binding(GO:0070411)
0.1 1.5 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.5 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 0.5 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 0.3 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1 1.1 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 1.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.3 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.1 0.2 GO:0017057 glucose-6-phosphate dehydrogenase activity(GO:0004345) 6-phosphogluconolactonase activity(GO:0017057)
0.1 0.2 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.1 0.2 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.1 0.3 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.3 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.0 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.5 GO:0097016 L27 domain binding(GO:0097016)
0.0 1.1 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.3 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.2 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.2 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.5 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.1 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 0.1 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.1 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0 0.1 GO:0001855 complement component C4b binding(GO:0001855)
0.0 0.2 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.0 2.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.5 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.2 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.1 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.0 0.2 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.2 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.2 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.1 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.4 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.2 GO:0015266 protein channel activity(GO:0015266)
0.0 0.4 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.4 GO:0070513 death domain binding(GO:0070513)
0.0 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.8 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.6 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.4 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.6 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.5 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.4 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 1.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)
0.0 0.8 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 0.3 GO:0071855 neuropeptide receptor binding(GO:0071855)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.8 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.8 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 1.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 1.8 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.7 PID FOXO PATHWAY FoxO family signaling
0.0 0.8 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.5 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.8 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.3 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.5 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.8 PID BMP PATHWAY BMP receptor signaling
0.0 0.5 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.0 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 2.7 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 1.0 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 1.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.6 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.8 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.9 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.7 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.5 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 1.5 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.8 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 1.1 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.5 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.3 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.5 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.2 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network