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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for TFAP2B

Z-value: 0.98

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Transcription factors associated with TFAP2B

Gene Symbol Gene ID Gene Info
ENSG00000008196.8 transcription factor AP-2 beta

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TFAP2Bhg19_v2_chr6_+_50786414_507864390.262.1e-01Click!

Activity profile of TFAP2B motif

Sorted Z-values of TFAP2B motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_27213893 1.99 ENST00000283921.4
homeobox A10
chr16_+_30960375 1.88 ENST00000318663.4
ENST00000566237.1
ENST00000562699.1
ORAI calcium release-activated calcium modulator 3
chr2_+_45878790 1.58 ENST00000306156.3
protein kinase C, epsilon
chr19_+_45971246 1.50 ENST00000585836.1
ENST00000417353.2
ENST00000353609.3
ENST00000591858.1
ENST00000443841.2
ENST00000590335.1
FBJ murine osteosarcoma viral oncogene homolog B
chr1_+_221054584 1.11 ENST00000549319.1
H2.0-like homeobox
chr16_-_88772761 1.10 ENST00000567844.1
ENST00000312838.4
ring finger protein 166
chr4_+_1723197 1.06 ENST00000485989.2
ENST00000313288.4
transforming, acidic coiled-coil containing protein 3
chr3_-_49459878 1.01 ENST00000546031.1
ENST00000458307.2
ENST00000430521.1
aminomethyltransferase
chr3_-_49459865 1.00 ENST00000427987.1
aminomethyltransferase
chr7_-_100065686 0.95 ENST00000423266.1
ENST00000456330.1
TSC22 domain family, member 4
chr1_+_163038565 0.85 ENST00000421743.2
regulator of G-protein signaling 4
chr9_-_124976154 0.83 ENST00000482062.1
LIM homeobox 6
chr9_-_124976185 0.82 ENST00000464484.2
LIM homeobox 6
chr12_-_53189892 0.80 ENST00000309505.3
ENST00000417996.2
keratin 3
chr1_-_44497024 0.80 ENST00000372306.3
ENST00000372310.3
ENST00000475075.2
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr17_-_72869140 0.77 ENST00000583917.1
ENST00000293195.5
ENST00000442102.2
ferredoxin reductase
chr17_-_72869086 0.77 ENST00000581530.1
ENST00000420580.2
ENST00000455107.2
ENST00000413947.2
ENST00000581219.1
ENST00000582944.1
ferredoxin reductase
chr22_-_51017084 0.75 ENST00000360719.2
ENST00000457250.1
ENST00000440709.1
carnitine palmitoyltransferase 1B (muscle)
chr12_-_122238913 0.75 ENST00000537157.1
AC084018.1
chr2_-_43453734 0.70 ENST00000282388.3
ZFP36 ring finger protein-like 2
chr11_-_19263145 0.69 ENST00000532666.1
ENST00000527884.1
E2F transcription factor 8
chr21_-_28217721 0.68 ENST00000284984.3
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr10_-_35930219 0.67 ENST00000374694.1
frizzled family receptor 8
chr1_+_33722080 0.66 ENST00000483388.1
ENST00000539719.1
zinc finger protein 362
chr1_+_33207381 0.66 ENST00000401073.2
KIAA1522
chr17_+_7758374 0.66 ENST00000301599.6
ENST00000574668.1
transmembrane protein 88
chr2_-_222436988 0.66 ENST00000409854.1
ENST00000281821.2
ENST00000392071.4
ENST00000443796.1
EPH receptor A4
chr22_-_31742218 0.63 ENST00000266269.5
ENST00000405309.3
ENST00000351933.4
POZ (BTB) and AT hook containing zinc finger 1
chr3_-_148804275 0.63 ENST00000392912.2
ENST00000465259.1
ENST00000310053.5
ENST00000494055.1
helicase-like transcription factor
chr8_-_11058847 0.62 ENST00000297303.4
ENST00000416569.2
XK, Kell blood group complex subunit-related family, member 6
chr1_-_1677358 0.61 ENST00000355439.2
ENST00000400924.1
ENST00000246421.4
solute carrier family 35, member E2
chr6_+_33378738 0.59 ENST00000374512.3
ENST00000374516.3
PHD finger protein 1
chr10_-_38146510 0.58 ENST00000395867.3
zinc finger protein 248
chr17_-_36906058 0.58 ENST00000580830.1
polycomb group ring finger 2
chr1_-_156399184 0.57 ENST00000368243.1
ENST00000357975.4
ENST00000310027.5
ENST00000400991.2
chromosome 1 open reading frame 61
chr16_-_28223166 0.57 ENST00000304658.5
exportin 6
chr6_-_31864977 0.55 ENST00000395728.3
ENST00000375528.4
euchromatic histone-lysine N-methyltransferase 2
chrX_-_154033793 0.55 ENST00000369534.3
ENST00000413259.3
membrane protein, palmitoylated 1, 55kDa
chrX_-_70474910 0.54 ENST00000373988.1
ENST00000373998.1
zinc finger, MYM-type 3
chr5_+_148521136 0.52 ENST00000506113.1
actin binding LIM protein family, member 3
chr1_-_49242553 0.52 ENST00000371833.3
BEN domain containing 5
chr15_+_96873921 0.52 ENST00000394166.3
nuclear receptor subfamily 2, group F, member 2
chr5_+_148521046 0.52 ENST00000326685.7
ENST00000356541.3
ENST00000309868.7
actin binding LIM protein family, member 3
chr10_+_99079008 0.52 ENST00000371021.3
frequently rearranged in advanced T-cell lymphomas
chr17_-_79869228 0.52 ENST00000570388.1
phosphate cytidylyltransferase 2, ethanolamine
chr3_+_39424828 0.50 ENST00000273158.4
ENST00000431510.1
solute carrier family 25, member 38
chr12_+_6493406 0.50 ENST00000543190.1
lymphotoxin beta receptor (TNFR superfamily, member 3)
chr13_+_60971427 0.50 ENST00000535286.1
ENST00000377881.2
tudor domain containing 3
chr22_-_19842330 0.49 ENST00000416337.1
ENST00000328554.4
ENST00000403325.1
ENST00000453108.1
chromosome 22 open reading frame 29
guanine nucleotide binding protein (G protein), beta polypeptide 1-like
chr7_+_101460882 0.48 ENST00000292535.7
ENST00000549414.2
ENST00000550008.2
ENST00000546411.2
ENST00000556210.1
cut-like homeobox 1
chr1_-_44497118 0.48 ENST00000537678.1
ENST00000466926.1
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr7_-_100425112 0.48 ENST00000358173.3
EPH receptor B4
chr3_-_39195037 0.47 ENST00000273153.5
cysteine-serine-rich nuclear protein 1
chr13_+_39612485 0.47 ENST00000379599.2
NHL repeat containing 3
chr6_+_24495185 0.47 ENST00000348925.2
aldehyde dehydrogenase 5 family, member A1
chr5_+_148521381 0.47 ENST00000504238.1
actin binding LIM protein family, member 3
chr14_-_88789581 0.46 ENST00000319231.5
potassium channel, subfamily K, member 10
chr22_-_36018569 0.46 ENST00000419229.1
ENST00000406324.1
myoglobin
chr19_+_41107249 0.46 ENST00000396819.3
latent transforming growth factor beta binding protein 4
chr4_-_1723040 0.46 ENST00000382936.3
ENST00000536901.1
ENST00000303277.2
transmembrane protein 129
chr14_+_92980111 0.46 ENST00000216487.7
ENST00000557762.1
Ras and Rab interactor 3
chr12_+_19282713 0.46 ENST00000299275.6
ENST00000539256.1
ENST00000538714.1
pleckstrin homology domain containing, family A member 5
chr13_+_39612442 0.45 ENST00000470258.1
ENST00000379600.3
NHL repeat containing 3
chr12_-_52585765 0.45 ENST00000313234.5
ENST00000394815.2
keratin 80
chr5_+_122181279 0.45 ENST00000395451.4
ENST00000506996.1
sorting nexin 24
chr1_+_153746683 0.45 ENST00000271857.2
solute carrier family 27 (fatty acid transporter), member 3
chr5_+_61708582 0.45 ENST00000325324.6
importin 11
chr5_+_149737202 0.44 ENST00000451292.1
ENST00000377797.3
ENST00000445265.2
ENST00000323668.7
ENST00000439160.2
ENST00000394269.3
ENST00000427724.2
ENST00000504761.2
ENST00000513346.1
ENST00000515516.1
Treacher Collins-Franceschetti syndrome 1
chr16_-_71323271 0.44 ENST00000565850.1
ENST00000568910.1
ENST00000434935.2
ENST00000338099.5
cap methyltransferase 2
chr17_-_79869004 0.44 ENST00000573927.1
ENST00000331285.3
ENST00000572157.1
phosphate cytidylyltransferase 2, ethanolamine
chr4_+_8271471 0.43 ENST00000307358.2
ENST00000382512.3
HtrA serine peptidase 3
chr17_-_79869243 0.42 ENST00000538721.2
ENST00000573636.2
ENST00000571105.1
ENST00000576343.1
ENST00000572473.1
phosphate cytidylyltransferase 2, ethanolamine
chr16_-_28222797 0.42 ENST00000569951.1
ENST00000565698.1
exportin 6
chr16_+_81478775 0.42 ENST00000537098.3
c-Maf inducing protein
chr1_-_40782938 0.42 ENST00000372736.3
ENST00000372748.3
collagen, type IX, alpha 2
chr12_+_6493319 0.42 ENST00000536876.1
lymphotoxin beta receptor (TNFR superfamily, member 3)
chr11_-_6677018 0.42 ENST00000299441.3
dachsous cadherin-related 1
chr11_-_63536113 0.42 ENST00000433688.1
ENST00000546282.2
chromosome 11 open reading frame 95
RP11-466C23.4
chr12_-_48152611 0.41 ENST00000389212.3
Rap guanine nucleotide exchange factor (GEF) 3
chr22_+_21987005 0.41 ENST00000607942.1
ENST00000425975.1
ENST00000292779.3
coiled-coil domain containing 116
chr17_-_79869077 0.41 ENST00000570391.1
phosphate cytidylyltransferase 2, ethanolamine
chr1_-_20812690 0.41 ENST00000375078.3
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr6_+_35227449 0.40 ENST00000373953.3
ENST00000440666.2
ENST00000339411.5
zinc finger protein 76
chr17_+_34087888 0.40 ENST00000586491.1
ENST00000588628.1
ENST00000285023.4
chromosome 17 open reading frame 50
chr2_+_120770581 0.40 ENST00000263713.5
erythrocyte membrane protein band 4.1 like 5
chr3_-_23958506 0.40 ENST00000425478.2
NFKB inhibitor interacting Ras-like 1
chr17_-_5487768 0.40 ENST00000269280.4
ENST00000345221.3
ENST00000262467.5
NLR family, pyrin domain containing 1
chrX_-_19905703 0.40 ENST00000397821.3
SH3-domain kinase binding protein 1
chr12_-_48152853 0.40 ENST00000171000.4
Rap guanine nucleotide exchange factor (GEF) 3
chr3_+_100211412 0.40 ENST00000323523.4
ENST00000403410.1
ENST00000449609.1
transmembrane protein 45A
chr3_-_23958402 0.39 ENST00000415901.2
ENST00000416026.2
ENST00000412028.1
ENST00000388759.3
ENST00000437230.1
NFKB inhibitor interacting Ras-like 1
chr3_-_10052763 0.39 ENST00000383808.2
ENST00000426698.1
ENST00000470827.2
AC022007.5
ER membrane protein complex subunit 3
chr3_-_49170405 0.38 ENST00000305544.4
ENST00000494831.1
laminin, beta 2 (laminin S)
chr7_+_65958693 0.37 ENST00000445681.1
ENST00000452565.1
GS1-124K5.4
chr22_+_31892373 0.37 ENST00000443011.1
ENST00000400289.1
ENST00000444859.1
ENST00000400288.2
Sfi1 homolog, spindle assembly associated (yeast)
chr16_-_30538079 0.36 ENST00000562803.1
zinc finger protein 768
chr3_-_49170522 0.36 ENST00000418109.1
laminin, beta 2 (laminin S)
chr8_+_56792377 0.36 ENST00000520220.2
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr11_+_117198545 0.36 ENST00000533153.1
ENST00000278935.3
ENST00000525416.1
centrosomal protein 164kDa
chrX_+_152338301 0.36 ENST00000453825.2
paraneoplastic Ma antigen family member 6A
chr3_-_56502375 0.36 ENST00000288221.6
ELKS/RAB6-interacting/CAST family member 2
chr1_-_147245484 0.36 ENST00000271348.2
gap junction protein, alpha 5, 40kDa
chr17_+_47448102 0.35 ENST00000576461.1
Uncharacterized protein
chr7_+_150076406 0.35 ENST00000329630.5
zinc finger protein 775
chr1_-_155006224 0.35 ENST00000368424.3
DC-STAMP domain containing 2
chr14_+_94393605 0.34 ENST00000556222.1
ENST00000554404.1
ENST00000557000.2
family with sequence similarity 181, member A
chr11_+_10326612 0.34 ENST00000534464.1
ENST00000530439.1
ENST00000524948.1
ENST00000528655.1
ENST00000526492.1
ENST00000525063.1
adrenomedullin
chr10_-_99393242 0.34 ENST00000370635.3
ENST00000478953.1
ENST00000335628.3
MORN repeat containing 4
chr12_-_57634475 0.34 ENST00000393825.1
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr20_+_2673383 0.33 ENST00000380648.4
ENST00000342725.5
early B-cell factor 4
chr2_+_44396000 0.33 ENST00000409895.4
ENST00000409432.3
ENST00000282412.4
ENST00000378551.2
ENST00000345249.4
protein phosphatase, Mg2+/Mn2+ dependent, 1B
chr17_-_66287257 0.33 ENST00000327268.4
solute carrier family 16, member 6
chr1_+_155293702 0.33 ENST00000368347.4
RUN and SH3 domain containing 1
chr1_+_154377669 0.33 ENST00000368485.3
ENST00000344086.4
interleukin 6 receptor
chr2_-_220408430 0.33 ENST00000243776.6
chondroitin polymerizing factor
chr3_-_185216811 0.33 ENST00000421852.1
transmembrane protein 41A
chr17_-_39677971 0.33 ENST00000393976.2
keratin 15
chr22_+_50781723 0.33 ENST00000359139.3
ENST00000395741.3
ENST00000395744.3
protein phosphatase 6, regulatory subunit 2
chr12_+_53693466 0.33 ENST00000267103.5
ENST00000548632.1
chromosome 12 open reading frame 10
chr17_-_73257667 0.32 ENST00000538886.1
ENST00000580799.1
ENST00000351904.7
ENST00000537686.1
golgi-associated, gamma adaptin ear containing, ARF binding protein 3
chr6_+_24495067 0.32 ENST00000357578.3
ENST00000546278.1
ENST00000491546.1
aldehyde dehydrogenase 5 family, member A1
chr11_+_64001962 0.32 ENST00000309422.2
vascular endothelial growth factor B
chrX_+_49028265 0.32 ENST00000376322.3
ENST00000376327.5
proteolipid protein 2 (colonic epithelium-enriched)
chr1_+_22970119 0.32 ENST00000374640.4
ENST00000374639.3
ENST00000374637.1
complement component 1, q subcomponent, C chain
chr16_-_49890016 0.32 ENST00000563137.2
zinc finger protein 423
chr1_+_64059332 0.32 ENST00000540265.1
phosphoglucomutase 1
chr19_-_49149553 0.32 ENST00000084798.4
carbonic anhydrase XI
chr4_+_26862431 0.32 ENST00000465503.1
stromal interaction molecule 2
chr1_+_33352036 0.32 ENST00000373467.3
hippocalcin
chr12_-_96184533 0.32 ENST00000343702.4
ENST00000344911.4
netrin 4
chr9_+_35792151 0.31 ENST00000342694.2
natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
chr10_-_99393208 0.31 ENST00000307450.6
MORN repeat containing 4
chr1_+_6845578 0.31 ENST00000467404.2
ENST00000439411.2
calmodulin binding transcription activator 1
chr13_+_99853124 0.31 ENST00000376440.2
ENST00000457666.1
UBA domain containing 2
chr19_+_35645618 0.30 ENST00000392218.2
ENST00000543307.1
ENST00000392219.2
ENST00000541435.2
ENST00000590686.1
ENST00000342879.3
ENST00000588699.1
FXYD domain containing ion transport regulator 5
chr12_-_52995291 0.30 ENST00000293745.2
ENST00000354310.4
keratin 72
chr7_+_44143925 0.30 ENST00000223357.3
AE binding protein 1
chr1_-_27286897 0.30 ENST00000320567.5
chromosome 1 open reading frame 172
chr19_+_35645817 0.30 ENST00000423817.3
FXYD domain containing ion transport regulator 5
chr11_+_117198801 0.30 ENST00000527609.1
ENST00000533570.1
centrosomal protein 164kDa
chr4_+_26862400 0.30 ENST00000467011.1
ENST00000412829.2
stromal interaction molecule 2
chr14_+_90528109 0.29 ENST00000282146.4
potassium channel, subfamily K, member 13
chr11_+_64002292 0.29 ENST00000426086.2
vascular endothelial growth factor B
chr12_+_7037461 0.29 ENST00000396684.2
atrophin 1
chr16_+_57126428 0.29 ENST00000290776.8
copine II
chr16_-_30537839 0.29 ENST00000380412.5
zinc finger protein 768
chrX_+_152240819 0.28 ENST00000421798.3
ENST00000535416.1
paraneoplastic Ma antigen family member 6C
paraneoplastic Ma antigen family member 6A
chr12_-_52995242 0.28 ENST00000537672.2
keratin 72
chr16_+_57126482 0.28 ENST00000537605.1
ENST00000535318.2
copine II
chr20_-_50808290 0.28 ENST00000346617.4
ENST00000371515.4
ENST00000371518.2
ZFP64 zinc finger protein
chr2_-_55459437 0.28 ENST00000401408.1
clathrin heavy chain linker domain containing 1
chr10_+_124221036 0.28 ENST00000368984.3
HtrA serine peptidase 1
chr14_+_79746249 0.28 ENST00000428277.2
neurexin 3
chr17_+_18163848 0.27 ENST00000323019.4
ENST00000578174.1
ENST00000395704.4
ENST00000395703.4
ENST00000578621.1
ENST00000579341.1
mitochondrial elongation factor 2
chr15_-_41624685 0.27 ENST00000560640.1
ENST00000220514.3
Opa interacting protein 5
chr14_+_105047478 0.27 ENST00000410013.1
chromosome 14 open reading frame 180
chr2_-_55459294 0.27 ENST00000407122.1
ENST00000406437.2
clathrin heavy chain linker domain containing 1
chr8_-_144655141 0.27 ENST00000398882.3
maestro heat-like repeat family member 6
chr17_+_59529743 0.27 ENST00000589003.1
ENST00000393853.4
T-box 4
chr12_-_52995210 0.27 ENST00000398066.3
keratin 72
chr19_-_41859814 0.26 ENST00000221930.5
transforming growth factor, beta 1
chr11_+_7273181 0.26 ENST00000318881.6
synaptotagmin IX
chr2_+_74741569 0.26 ENST00000233638.7
T-cell leukemia homeobox 2
chr16_-_10674528 0.26 ENST00000359543.3
epithelial membrane protein 2
chr22_+_31742875 0.26 ENST00000504184.2
CDNA FLJ20464 fis, clone KAT06158; HCG1777549; Uncharacterized protein
chr19_+_54024251 0.26 ENST00000253144.9
zinc finger protein 331
chr19_+_42387228 0.26 ENST00000354532.3
ENST00000599846.1
ENST00000347545.4
Rho guanine nucleotide exchange factor (GEF) 1
chr16_+_88772866 0.26 ENST00000453996.2
ENST00000312060.5
ENST00000378384.3
ENST00000567949.1
ENST00000564921.1
cytosolic thiouridylase subunit 2 homolog (S. pombe)
chr9_-_131534160 0.26 ENST00000291900.2
zyg-11 related, cell cycle regulator
chr2_+_28113583 0.26 ENST00000344773.2
ENST00000379624.1
ENST00000342045.2
ENST00000379632.2
ENST00000361704.2
brain and reproductive organ-expressed (TNFRSF1A modulator)
chr16_-_30381580 0.26 ENST00000409939.3
TBC1 domain family, member 10B
chr1_+_209602609 0.26 ENST00000458250.1
MIR205 host gene (non-protein coding)
chr1_-_15911510 0.25 ENST00000375826.3
agmatine ureohydrolase (agmatinase)
chrX_-_47863348 0.25 ENST00000376943.3
ENST00000396965.1
ENST00000305127.6
zinc finger protein 182
chr5_-_79287060 0.25 ENST00000512560.1
ENST00000509852.1
ENST00000512528.1
metaxin 3
chr12_+_52400719 0.25 ENST00000293662.4
GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
chr4_+_26862313 0.25 ENST00000467087.1
ENST00000382009.3
ENST00000237364.5
stromal interaction molecule 2
chr1_+_11994715 0.25 ENST00000449038.1
ENST00000376369.3
ENST00000429000.2
ENST00000196061.4
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
chr17_-_48227877 0.25 ENST00000316878.6
protein phosphatase 1, regulatory subunit 9B
chr3_-_123168551 0.25 ENST00000462833.1
adenylate cyclase 5
chr8_+_56792355 0.25 ENST00000519728.1
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr1_-_161039647 0.25 ENST00000368013.3
Rho GTPase activating protein 30
chr2_-_28113965 0.25 ENST00000302188.3
ribokinase
chr9_+_133971863 0.25 ENST00000372309.3
allograft inflammatory factor 1-like
chr9_-_140009130 0.25 ENST00000497375.1
ENST00000371579.2
dipeptidyl-peptidase 7
chr1_-_54637997 0.25 ENST00000536061.1
CDNA: FLJ21031 fis, clone CAE07336; HCG1780521; Uncharacterized protein
chr12_-_112037306 0.25 ENST00000535949.1
ENST00000542287.2
ENST00000377617.3
ENST00000550104.1
ataxin 2
chr2_-_158732340 0.25 ENST00000539637.1
ENST00000413751.1
ENST00000434821.1
ENST00000424669.1
activin A receptor, type I
chr17_+_4613918 0.25 ENST00000574954.1
ENST00000346341.2
ENST00000572457.1
ENST00000381488.6
ENST00000412477.3
ENST00000571428.1
ENST00000575877.1
arrestin, beta 2
chr7_+_150549565 0.24 ENST00000360937.4
ENST00000416793.2
ENST00000483043.1
amine oxidase, copper containing 1
chr14_+_79745746 0.24 ENST00000281127.7
neurexin 3
chr17_-_36904437 0.24 ENST00000585100.1
ENST00000360797.2
ENST00000578109.1
ENST00000579882.1
polycomb group ring finger 2
chr1_-_161039753 0.24 ENST00000368015.1
Rho GTPase activating protein 30
chr14_+_24458093 0.24 ENST00000558753.1
ENST00000537912.1
dehydrogenase/reductase (SDR family) member 4 like 2
chr1_-_161039456 0.24 ENST00000368016.3
Rho GTPase activating protein 30
chr9_+_133971909 0.24 ENST00000247291.3
ENST00000372302.1
ENST00000372300.1
ENST00000372298.1
allograft inflammatory factor 1-like
chr21_-_45078019 0.24 ENST00000542962.1
heat shock transcription factor 2 binding protein
chr1_+_228337553 0.24 ENST00000366714.2
gap junction protein, gamma 2, 47kDa
chr16_+_6533380 0.24 ENST00000552089.1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr8_+_22844913 0.24 ENST00000519685.1
Rho-related BTB domain containing 2

Network of associatons between targets according to the STRING database.

First level regulatory network of TFAP2B

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0035669 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.4 1.3 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.4 2.0 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.2 0.7 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.2 0.9 GO:0030822 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.2 0.7 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.2 0.6 GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.2 0.6 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.2 2.7 GO:0002115 store-operated calcium entry(GO:0002115)
0.2 0.6 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.1 0.7 GO:0072313 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.1 0.4 GO:0003192 mitral valve formation(GO:0003192)
0.1 1.1 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 0.8 GO:0006083 acetate metabolic process(GO:0006083) gamma-aminobutyric acid catabolic process(GO:0009450)
0.1 0.5 GO:0009956 radial pattern formation(GO:0009956)
0.1 1.6 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 0.4 GO:0003193 pulmonary valve formation(GO:0003193) regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652) foramen ovale closure(GO:0035922) regulation of bundle of His cell action potential(GO:0098905)
0.1 0.2 GO:0031133 regulation of axon diameter(GO:0031133)
0.1 0.3 GO:0002384 hepatic immune response(GO:0002384)
0.1 1.0 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.4 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.1 0.6 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 0.3 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1 0.3 GO:0097187 dentinogenesis(GO:0097187)
0.1 0.3 GO:0046732 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528) negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.1 0.3 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.1 0.3 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 0.3 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.1 0.3 GO:1902075 cellular response to salt(GO:1902075)
0.1 0.7 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.1 0.3 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 0.2 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1 0.2 GO:0021569 rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 0.2 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.1 0.6 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.1 0.7 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.1 0.2 GO:0060319 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854) primitive erythrocyte differentiation(GO:0060319)
0.1 1.8 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 0.4 GO:2000664 positive regulation of interleukin-5 secretion(GO:2000664)
0.1 1.5 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 0.3 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 2.1 GO:0060065 uterus development(GO:0060065)
0.1 0.2 GO:0060152 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.1 0.4 GO:0080009 mRNA methylation(GO:0080009)
0.1 0.2 GO:0003274 endocardial cushion fusion(GO:0003274)
0.1 0.2 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.1 0.5 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.1 0.1 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.1 0.3 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.1 0.2 GO:0003335 corneocyte development(GO:0003335)
0.1 0.2 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 0.2 GO:0070318 response to anoxia(GO:0034059) positive regulation of G0 to G1 transition(GO:0070318)
0.1 0.3 GO:1901162 primary amino compound biosynthetic process(GO:1901162)
0.0 0.2 GO:0019303 D-ribose catabolic process(GO:0019303)
0.0 0.2 GO:0019087 transformation of host cell by virus(GO:0019087)
0.0 0.3 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0 0.2 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.3 GO:0000189 MAPK import into nucleus(GO:0000189) regulation of Golgi inheritance(GO:0090170)
0.0 0.1 GO:0019860 uracil metabolic process(GO:0019860)
0.0 0.3 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.0 0.5 GO:0015816 glycine transport(GO:0015816)
0.0 0.2 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.0 0.3 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.0 0.2 GO:0034182 regulation of maintenance of sister chromatid cohesion(GO:0034091) regulation of maintenance of mitotic sister chromatid cohesion(GO:0034182) negative regulation of sister chromatid cohesion(GO:0045875) protein auto-ADP-ribosylation(GO:0070213)
0.0 0.2 GO:0071504 cellular response to heparin(GO:0071504)
0.0 0.2 GO:0035524 proline transport(GO:0015824) proline transmembrane transport(GO:0035524)
0.0 0.8 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 1.0 GO:0051412 response to corticosterone(GO:0051412)
0.0 0.1 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.0 0.2 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228) ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938) metanephric renal vesicle formation(GO:0072093)
0.0 0.1 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.0 0.2 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.0 0.1 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.0 0.4 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.7 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.1 GO:0071624 positive regulation of granulocyte chemotaxis(GO:0071624)
0.0 0.3 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.3 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.2 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.1 GO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919)
0.0 0.1 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.6 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.0 0.1 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.3 GO:0070836 caveola assembly(GO:0070836)
0.0 0.4 GO:0014029 neural crest formation(GO:0014029)
0.0 0.1 GO:0060139 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.0 0.1 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.2 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.0 0.5 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.1 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.2 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.0 0.3 GO:2000111 positive regulation of macrophage apoptotic process(GO:2000111)
0.0 0.1 GO:0072301 negative regulation of metanephric glomerulus development(GO:0072299) regulation of metanephric glomerular mesangial cell proliferation(GO:0072301) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.0 0.1 GO:0002159 desmosome assembly(GO:0002159) endothelial cell-cell adhesion(GO:0071603)
0.0 0.1 GO:0015798 myo-inositol transport(GO:0015798)
0.0 0.3 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.2 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.2 GO:0015793 glycerol transport(GO:0015793)
0.0 0.3 GO:0048484 enteric nervous system development(GO:0048484)
0.0 0.1 GO:0098904 regulation of AV node cell action potential(GO:0098904)
0.0 0.1 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.3 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.1 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.1 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.0 0.4 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.1 GO:0061760 antifungal innate immune response(GO:0061760)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.3 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.2 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.0 0.3 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.5 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.1 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.3 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653) positive regulation of cell cycle checkpoint(GO:1901978)
0.0 0.1 GO:0015942 10-formyltetrahydrofolate biosynthetic process(GO:0009257) formate metabolic process(GO:0015942)
0.0 0.5 GO:0030252 growth hormone secretion(GO:0030252)
0.0 1.3 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.0 1.1 GO:0007091 metaphase/anaphase transition of mitotic cell cycle(GO:0007091)
0.0 0.7 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 0.8 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.5 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.0 0.2 GO:0048102 autophagic cell death(GO:0048102)
0.0 0.2 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.1 GO:0006449 regulation of translational termination(GO:0006449)
0.0 1.5 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.2 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.2 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.0 0.2 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.0 0.1 GO:0070316 regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.0 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.1 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.1 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.2 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 1.1 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.1 GO:0014050 negative regulation of glutamate secretion(GO:0014050) regulation of serotonin secretion(GO:0014062) negative regulation of serotonin secretion(GO:0014063)
0.0 0.5 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.1 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.1 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.4 GO:0050718 positive regulation of interleukin-1 beta secretion(GO:0050718)
0.0 0.1 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.1 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.0 GO:0021592 midbrain-hindbrain boundary morphogenesis(GO:0021555) fourth ventricle development(GO:0021592)
0.0 0.2 GO:0070233 negative regulation of T cell apoptotic process(GO:0070233)
0.0 0.4 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.4 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.0 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.0 0.1 GO:0060033 anatomical structure regression(GO:0060033)
0.0 1.1 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.2 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.2 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0005608 laminin-3 complex(GO:0005608)
0.2 0.7 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.1 0.6 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.1 0.3 GO:0044609 DBIRD complex(GO:0044609)
0.1 0.4 GO:0005594 collagen type IX trimer(GO:0005594)
0.1 0.3 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.8 GO:0001739 sex chromatin(GO:0001739)
0.1 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.4 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.3 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.2 GO:0097513 myosin II filament(GO:0097513)
0.0 0.2 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.4 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.4 GO:0045179 apical cortex(GO:0045179)
0.0 0.2 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.7 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.2 GO:0070847 core mediator complex(GO:0070847)
0.0 0.3 GO:0044327 dendritic spine head(GO:0044327)
0.0 2.2 GO:0045095 keratin filament(GO:0045095)
0.0 0.4 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.2 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.6 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.5 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.3 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.4 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.4 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.2 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 0.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.1 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.1 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.3 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.3 GO:0010369 chromocenter(GO:0010369)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0016731 ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
0.5 2.0 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.4 1.8 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.3 1.3 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.3 1.6 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.2 2.7 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.4 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.1 0.8 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.1 0.3 GO:0004915 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.1 0.6 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.4 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.1 0.3 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.1 0.3 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 0.2 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.1 0.6 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 0.2 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.1 0.6 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 0.5 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 0.2 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 1.1 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.9 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.7 GO:0042731 PH domain binding(GO:0042731)
0.1 0.4 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.1 0.2 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.1 0.3 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.2 GO:0033906 protein tyrosine kinase inhibitor activity(GO:0030292) hyaluronoglucuronidase activity(GO:0033906)
0.0 0.2 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.2 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.4 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.3 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.2 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.3 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.3 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.7 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822) inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.4 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.2 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.7 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.2 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.4 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.8 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.3 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.7 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.2 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.2 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.5 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.5 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.1 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 1.4 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.4 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.5 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 1.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.2 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.1 GO:1902444 riboflavin binding(GO:1902444)
0.0 0.5 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.4 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.5 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.4 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.2 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 0.1 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 0.1 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.3 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.1 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.1 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0 0.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.0 0.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.3 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.6 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.3 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.5 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.5 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 1.1 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.1 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.2 GO:0001163 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.3 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.4 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.1 GO:0008199 ferric iron binding(GO:0008199)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.1 1.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.5 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.9 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.6 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.3 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.5 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.3 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.5 PID ARF 3PATHWAY Arf1 pathway
0.0 1.4 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.0 PID AURORA A PATHWAY Aurora A signaling
0.0 0.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.5 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.9 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.9 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.5 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 1.5 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.5 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 1.1 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.8 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 1.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.3 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.6 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.7 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 1.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.2 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.8 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.5 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.2 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.7 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.2 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.2 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.3 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.3 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.4 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.5 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.6 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.2 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.6 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.2 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.1 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.1 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.6 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.4 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation