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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for TFAP4_MSC

Z-value: 0.48

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Transcription factors associated with TFAP4_MSC

Gene Symbol Gene ID Gene Info
ENSG00000090447.7 transcription factor AP-4
ENSG00000178860.8 musculin

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MSChg19_v2_chr8_-_72756667_727567360.125.5e-01Click!
TFAP4hg19_v2_chr16_-_4323015_43230760.039.0e-01Click!

Activity profile of TFAP4_MSC motif

Sorted Z-values of TFAP4_MSC motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_225811747 1.29 ENST00000409592.3
dedicator of cytokinesis 10
chr1_+_212738676 0.65 ENST00000366981.4
ENST00000366987.2
activating transcription factor 3
chr2_-_175629135 0.63 ENST00000409542.1
ENST00000409219.1
cholinergic receptor, nicotinic, alpha 1 (muscle)
chr2_+_33701286 0.61 ENST00000403687.3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr8_+_81398444 0.59 ENST00000455036.3
ENST00000426744.2
zinc finger and BTB domain containing 10
chr4_+_74702214 0.59 ENST00000226317.5
ENST00000515050.1
chemokine (C-X-C motif) ligand 6
chrX_-_11445856 0.58 ENST00000380736.1
Rho GTPase activating protein 6
chr5_-_16936340 0.58 ENST00000507288.1
ENST00000513610.1
myosin X
chr13_-_43566301 0.51 ENST00000398762.3
ENST00000313640.7
ENST00000313624.7
epithelial stromal interaction 1 (breast)
chr1_+_172422026 0.50 ENST00000367725.4
chromosome 1 open reading frame 105
chr1_-_243326612 0.46 ENST00000492145.1
ENST00000490813.1
ENST00000464936.1
centrosomal protein 170kDa
chr4_-_74864386 0.44 ENST00000296027.4
chemokine (C-X-C motif) ligand 5
chr3_+_23244511 0.37 ENST00000425792.1
ubiquitin-conjugating enzyme E2E 2
chr1_-_38273840 0.37 ENST00000373044.2
yrdC N(6)-threonylcarbamoyltransferase domain containing
chr1_-_150669500 0.34 ENST00000271732.3
golgi phosphoprotein 3-like
chr15_-_40401062 0.32 ENST00000354670.4
ENST00000559701.1
ENST00000557870.1
ENST00000558774.1
Bcl2 modifying factor
chr19_+_36249044 0.32 ENST00000444637.2
ENST00000396908.4
ENST00000544099.1
chromosome 19 open reading frame 55
chr20_+_53092123 0.32 ENST00000262593.5
docking protein 5
chr5_+_113697983 0.31 ENST00000264773.3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr20_+_53092232 0.31 ENST00000395939.1
docking protein 5
chr2_-_175629164 0.30 ENST00000409323.1
ENST00000261007.5
ENST00000348749.5
cholinergic receptor, nicotinic, alpha 1 (muscle)
chr12_-_57522813 0.30 ENST00000556155.1
signal transducer and activator of transcription 6, interleukin-4 induced
chr11_+_7506713 0.30 ENST00000329293.3
ENST00000534244.1
olfactomedin-like 1
chr2_+_97203082 0.30 ENST00000454558.2
AT rich interactive domain 5A (MRF1-like)
chr6_-_128841503 0.30 ENST00000368215.3
ENST00000532331.1
ENST00000368213.5
ENST00000368207.3
ENST00000525459.1
ENST00000368210.3
ENST00000368226.4
ENST00000368227.3
protein tyrosine phosphatase, receptor type, K
chr9_+_125796806 0.30 ENST00000373642.1
G protein-coupled receptor 21
chr19_+_36249057 0.29 ENST00000301165.5
ENST00000536950.1
ENST00000537459.1
ENST00000421853.2
chromosome 19 open reading frame 55
chr8_+_81397876 0.29 ENST00000430430.1
zinc finger and BTB domain containing 10
chr21_-_34185944 0.29 ENST00000479548.1
chromosome 21 open reading frame 62
chr11_-_117747434 0.29 ENST00000529335.2
ENST00000530956.1
ENST00000260282.4
FXYD domain containing ion transport regulator 6
chr9_+_102584128 0.28 ENST00000338488.4
ENST00000395097.2
nuclear receptor subfamily 4, group A, member 3
chr11_-_117747607 0.28 ENST00000540359.1
ENST00000539526.1
FXYD domain containing ion transport regulator 6
chr1_-_33336414 0.28 ENST00000373471.3
ENST00000609187.1
fibronectin type III domain containing 5
chr11_+_66742742 0.27 ENST00000308963.4
chromosome 11 open reading frame 86
chr11_-_117748138 0.27 ENST00000527717.1
FXYD domain containing ion transport regulator 6
chr8_+_128748308 0.27 ENST00000377970.2
v-myc avian myelocytomatosis viral oncogene homolog
chr20_+_33292068 0.27 ENST00000374810.3
ENST00000374809.2
ENST00000451665.1
tumor protein p53 inducible nuclear protein 2
chr12_+_32655110 0.27 ENST00000546442.1
ENST00000583694.1
FYVE, RhoGEF and PH domain containing 4
chr16_-_31076332 0.26 ENST00000539836.3
ENST00000535577.1
ENST00000442862.2
zinc finger protein 668
chr11_+_33061543 0.26 ENST00000432887.1
ENST00000528898.1
ENST00000531632.2
t-complex 11, testis-specific-like 1
chr10_+_80027105 0.25 ENST00000461034.1
ENST00000476909.1
ENST00000459633.1
long intergenic non-protein coding RNA 595
chr9_-_104357277 0.25 ENST00000374806.1
protein phosphatase 3, regulatory subunit B, beta
chr1_+_10271674 0.24 ENST00000377086.1
kinesin family member 1B
chr1_-_42384343 0.24 ENST00000372584.1
human immunodeficiency virus type I enhancer binding protein 3
chr15_-_42076229 0.24 ENST00000597767.1
Uncharacterized protein
chrX_+_70521584 0.23 ENST00000373829.3
ENST00000538820.1
integrin beta 1 binding protein (melusin) 2
chr12_+_69201923 0.22 ENST00000462284.1
ENST00000258149.5
ENST00000356290.4
ENST00000540827.1
ENST00000428863.2
ENST00000393412.3
MDM2 oncogene, E3 ubiquitin protein ligase
chr4_+_96012614 0.22 ENST00000264568.4
bone morphogenetic protein receptor, type IB
chr2_-_224810070 0.22 ENST00000429915.1
ENST00000233055.4
WD repeat and FYVE domain containing 1
chr17_+_33570055 0.22 ENST00000299977.4
ENST00000542451.1
ENST00000592325.1
schlafen family member 5
chr1_-_150849047 0.22 ENST00000354396.2
ENST00000505755.1
aryl hydrocarbon receptor nuclear translocator
chr7_+_55086794 0.21 ENST00000275493.2
ENST00000442591.1
epidermal growth factor receptor
chr11_+_64059464 0.21 ENST00000394525.2
potassium channel, subfamily K, member 4
chr4_-_153303658 0.21 ENST00000296555.5
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr7_+_18535786 0.21 ENST00000406072.1
histone deacetylase 9
chr2_+_192110199 0.21 ENST00000304164.4
myosin IB
chr2_-_235405168 0.21 ENST00000339728.3
ADP-ribosylation factor-like 4C
chr16_-_31076273 0.21 ENST00000426488.2
zinc finger protein 668
chr1_-_150849174 0.21 ENST00000515192.1
aryl hydrocarbon receptor nuclear translocator
chr6_+_151042224 0.20 ENST00000358517.2
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr10_+_91087651 0.20 ENST00000371818.4
interferon-induced protein with tetratricopeptide repeats 3
chr4_+_142558078 0.20 ENST00000529613.1
interleukin 15
chr2_+_97202480 0.19 ENST00000357485.3
AT rich interactive domain 5A (MRF1-like)
chr2_+_26568965 0.19 ENST00000260585.7
ENST00000447170.1
ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)
chrY_+_14774265 0.19 ENST00000457658.1
ENST00000440408.1
ENST00000543097.1
testis-specific transcript, Y-linked 15 (non-protein coding)
chr4_+_7045042 0.19 ENST00000310074.7
ENST00000512388.1
transcriptional adaptor 2B
chr15_-_67546963 0.19 ENST00000561452.1
ENST00000261880.5
alpha- and gamma-adaptin binding protein
chr8_-_20040601 0.19 ENST00000265808.7
ENST00000522513.1
solute carrier family 18 (vesicular monoamine transporter), member 1
chr8_-_37457350 0.19 ENST00000519691.1
RP11-150O12.3
chr8_-_71519889 0.18 ENST00000521425.1
translocation associated membrane protein 1
chr8_-_20040638 0.18 ENST00000519026.1
ENST00000276373.5
ENST00000440926.1
ENST00000437980.1
solute carrier family 18 (vesicular monoamine transporter), member 1
chr5_-_58571935 0.18 ENST00000503258.1
phosphodiesterase 4D, cAMP-specific
chr11_+_20044096 0.18 ENST00000533917.1
neuron navigator 2
chr12_-_86650045 0.18 ENST00000604798.1
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr5_+_66124590 0.18 ENST00000490016.2
ENST00000403666.1
ENST00000450827.1
microtubule associated serine/threonine kinase family member 4
chr10_-_29923893 0.18 ENST00000355867.4
supervillin
chr7_+_48128854 0.17 ENST00000436673.1
ENST00000429491.2
uridine phosphorylase 1
chr1_+_14075903 0.17 ENST00000343137.4
ENST00000503842.1
ENST00000407521.3
ENST00000505823.1
PR domain containing 2, with ZNF domain
chr6_+_44184653 0.17 ENST00000573382.2
ENST00000576476.1
RP1-302G2.5
chr1_+_14075865 0.17 ENST00000413440.1
PR domain containing 2, with ZNF domain
chr12_+_12938541 0.17 ENST00000356591.4
apolipoprotein L domain containing 1
chr1_-_165414414 0.17 ENST00000359842.5
retinoid X receptor, gamma
chr2_+_85981008 0.17 ENST00000306279.3
atonal homolog 8 (Drosophila)
chr19_-_2151523 0.17 ENST00000350812.6
ENST00000355272.6
ENST00000356926.4
ENST00000345016.5
adaptor-related protein complex 3, delta 1 subunit
chr18_+_55816546 0.17 ENST00000435432.2
ENST00000357895.5
ENST00000586263.1
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr7_+_48128816 0.17 ENST00000395564.4
uridine phosphorylase 1
chr1_-_183622442 0.17 ENST00000308641.4
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr12_-_53994805 0.17 ENST00000328463.7
activating transcription factor 7
chr9_-_130541017 0.16 ENST00000314830.8
SH2 domain containing 3C
chr20_-_10654639 0.16 ENST00000254958.5
jagged 1
chr2_-_27603582 0.16 ENST00000323703.6
ENST00000436006.1
zinc finger protein 513
chr5_+_49962772 0.16 ENST00000281631.5
ENST00000513738.1
ENST00000503665.1
ENST00000514067.2
ENST00000503046.1
poly (ADP-ribose) polymerase family, member 8
chr6_+_69942298 0.16 ENST00000238918.8
brain-specific angiogenesis inhibitor 3
chr12_-_70093190 0.16 ENST00000330891.5
bestrophin 3
chr8_-_74791051 0.16 ENST00000453587.2
ENST00000602969.1
ENST00000602593.1
ENST00000419880.3
ENST00000517608.1
ubiquitin-conjugating enzyme E2W (putative)
chr19_-_50432782 0.16 ENST00000413454.1
ENST00000596437.1
ENST00000341114.3
ENST00000595948.1
nucleoporin 62kDa
interleukin 4 induced 1
chr15_+_74287035 0.15 ENST00000395132.2
ENST00000268059.6
ENST00000354026.6
ENST00000268058.3
ENST00000565898.1
ENST00000569477.1
ENST00000569965.1
ENST00000567543.1
ENST00000436891.3
ENST00000435786.2
ENST00000564428.1
ENST00000359928.4
promyelocytic leukemia
chr7_+_48128194 0.15 ENST00000416681.1
ENST00000331803.4
ENST00000432131.1
uridine phosphorylase 1
chr15_-_72523924 0.15 ENST00000566809.1
ENST00000567087.1
ENST00000569050.1
ENST00000568883.1
pyruvate kinase, muscle
chr15_-_55562582 0.15 ENST00000396307.2
RAB27A, member RAS oncogene family
chr17_+_4981535 0.15 ENST00000318833.3
ZFP3 zinc finger protein
chr3_-_69101413 0.15 ENST00000398559.2
TATA element modulatory factor 1
chr3_-_69101461 0.15 ENST00000543976.1
TATA element modulatory factor 1
chr15_-_55563072 0.15 ENST00000567380.1
ENST00000565972.1
ENST00000569493.1
RAB27A, member RAS oncogene family
chr11_+_71938925 0.14 ENST00000538751.1
inositol polyphosphate phosphatase-like 1
chr15_-_55562479 0.14 ENST00000564609.1
RAB27A, member RAS oncogene family
chr11_+_66886717 0.14 ENST00000398645.2
lysine (K)-specific demethylase 2A
chr22_+_26138108 0.14 ENST00000536101.1
ENST00000335473.7
ENST00000407587.2
myosin XVIIIB
chr1_-_153931052 0.14 ENST00000368630.3
ENST00000368633.1
CREB regulated transcription coactivator 2
chr7_+_48128316 0.14 ENST00000341253.4
uridine phosphorylase 1
chr8_-_13134045 0.14 ENST00000512044.2
deleted in liver cancer 1
chr2_+_231280908 0.14 ENST00000427101.2
ENST00000432979.1
SP100 nuclear antigen
chr11_-_1587166 0.14 ENST00000331588.4
dual specificity phosphatase 8
chr7_+_43152191 0.14 ENST00000395891.2
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr10_-_111683308 0.14 ENST00000502935.1
ENST00000322238.8
ENST00000369680.4
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
chr15_+_93447675 0.14 ENST00000536619.1
chromodomain helicase DNA binding protein 2
chr9_-_130524695 0.13 ENST00000440630.1
ENST00000429553.1
SH2 domain containing 3C
chrX_+_64808248 0.13 ENST00000609672.1
moesin
chr18_-_19180681 0.13 ENST00000269214.5
establishment of sister chromatid cohesion N-acetyltransferase 1
chr2_-_158345462 0.13 ENST00000439355.1
ENST00000540637.1
cytohesin 1 interacting protein
chr15_+_74287009 0.13 ENST00000395135.3
promyelocytic leukemia
chr11_-_117747327 0.13 ENST00000584230.1
ENST00000527429.1
ENST00000584394.1
ENST00000532984.1
FXYD domain containing ion transport regulator 6
FXYD6-FXYD2 readthrough
chr13_+_113656022 0.13 ENST00000423482.2
MCF.2 cell line derived transforming sequence-like
chr10_-_64576105 0.13 ENST00000242480.3
ENST00000411732.1
early growth response 2
chr20_+_57875658 0.13 ENST00000371025.3
endothelin 3
chr6_-_34524093 0.13 ENST00000544425.1
SAM pointed domain containing ETS transcription factor
chr2_+_231280954 0.13 ENST00000409824.1
ENST00000409341.1
ENST00000409112.1
ENST00000340126.4
ENST00000341950.4
SP100 nuclear antigen
chr22_-_37823468 0.13 ENST00000402918.2
extracellular leucine-rich repeat and fibronectin type III domain containing 2
chr11_-_66725837 0.13 ENST00000393958.2
ENST00000393960.1
ENST00000524491.1
ENST00000355677.3
pyruvate carboxylase
chr16_-_21289627 0.13 ENST00000396023.2
ENST00000415987.2
crystallin, mu
chr15_+_74287118 0.13 ENST00000563500.1
promyelocytic leukemia
chr1_+_101003687 0.13 ENST00000315033.4
G protein-coupled receptor 88
chr1_+_22303503 0.13 ENST00000337107.6
chymotrypsin-like elastase family, member 3B
chr14_-_91282726 0.12 ENST00000328459.6
ENST00000357056.2
tetratricopeptide repeat domain 7B
chr3_+_3841108 0.12 ENST00000319331.3
leucine rich repeat neuronal 1
chr16_-_4323015 0.12 ENST00000204517.6
transcription factor AP-4 (activating enhancer binding protein 4)
chr3_+_149191723 0.12 ENST00000305354.4
transmembrane 4 L six family member 4
chr10_+_13142075 0.12 ENST00000378757.2
ENST00000430081.1
ENST00000378752.3
ENST00000378748.3
optineurin
chr10_+_13142225 0.12 ENST00000378747.3
optineurin
chr22_+_31644388 0.12 ENST00000333611.4
ENST00000340552.4
LIM domain kinase 2
chr15_-_83240507 0.12 ENST00000564522.1
ENST00000398592.2
cytoplasmic polyadenylation element binding protein 1
chr13_-_33859819 0.12 ENST00000336934.5
StAR-related lipid transfer (START) domain containing 13
chr7_+_62809239 0.12 ENST00000456890.1
AC006455.1
chr17_+_40996590 0.12 ENST00000253799.3
ENST00000452774.2
amine oxidase, copper containing 2 (retina-specific)
chr11_-_30608413 0.12 ENST00000528686.1
metallophosphoesterase domain containing 2
chr17_-_54893250 0.12 ENST00000397862.2
chromosome 17 open reading frame 67
chr7_-_92855762 0.11 ENST00000453812.2
ENST00000394468.2
HEPACAM family member 2
chr5_+_137419581 0.11 ENST00000506684.1
ENST00000504809.1
ENST00000398754.1
wingless-type MMTV integration site family, member 8A
chr1_+_25071848 0.11 ENST00000374379.4
chloride intracellular channel 4
chr16_+_77224732 0.11 ENST00000569610.1
ENST00000248248.3
ENST00000567291.1
ENST00000320859.6
ENST00000563612.1
ENST00000563279.1
MON1 secretory trafficking family member B
chr11_+_71498552 0.11 ENST00000346333.6
ENST00000359244.4
ENST00000426628.2
family with sequence similarity 86, member C1
chr11_-_66360548 0.11 ENST00000333861.3
coiled-coil domain containing 87
chr4_-_140477353 0.11 ENST00000406354.1
ENST00000506866.2
SET domain containing (lysine methyltransferase) 7
chr1_-_2461684 0.11 ENST00000378453.3
hes family bHLH transcription factor 5
chr3_-_119182523 0.11 ENST00000319172.5
transmembrane protein 39A
chr16_-_79634595 0.11 ENST00000326043.4
ENST00000393350.1
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
chr19_+_16187085 0.11 ENST00000300933.4
tropomyosin 4
chr10_-_73848531 0.11 ENST00000373109.2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr17_+_7341586 0.11 ENST00000575235.1
fibroblast growth factor 11
chr17_+_42925270 0.10 ENST00000253410.2
ENST00000587021.1
HIG1 hypoxia inducible domain family, member 1B
chr5_+_102201687 0.10 ENST00000304400.7
peptidylglycine alpha-amidating monooxygenase
chr2_+_233390863 0.10 ENST00000449596.1
ENST00000543200.1
cholinergic receptor, nicotinic, delta (muscle)
chr17_+_65040678 0.10 ENST00000226021.3
calcium channel, voltage-dependent, gamma subunit 1
chr2_-_17981462 0.10 ENST00000402989.1
ENST00000428868.1
structural maintenance of chromosomes 6
chr8_-_121824374 0.10 ENST00000517992.1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr20_-_48530230 0.10 ENST00000422556.1
spermatogenesis associated 2
chr6_-_133055896 0.10 ENST00000367927.5
ENST00000425515.2
ENST00000207771.3
ENST00000392393.3
ENST00000450865.2
ENST00000392394.2
vanin 3
chr9_-_35111420 0.10 ENST00000378557.1
family with sequence similarity 214, member B
chr12_+_6949964 0.10 ENST00000541978.1
ENST00000435982.2
guanine nucleotide binding protein (G protein), beta polypeptide 3
chr11_+_24518723 0.10 ENST00000336930.6
ENST00000529015.1
ENST00000533227.1
leucine zipper protein 2
chr4_-_80994210 0.10 ENST00000403729.2
anthrax toxin receptor 2
chr4_+_77172847 0.10 ENST00000515604.1
ENST00000539752.1
ENST00000424749.2
uncharacterized protein LOC100631383
FAM47E-STBD1 readthrough
family with sequence similarity 47, member E
chr10_+_81272287 0.10 ENST00000520547.2
eukaryotic translation initiation factor 5A-like 1
chr12_-_76879852 0.10 ENST00000548341.1
oxysterol binding protein-like 8
chr22_+_38071615 0.10 ENST00000215909.5
lectin, galactoside-binding, soluble, 1
chr12_-_133464151 0.09 ENST00000315585.7
ENST00000266880.7
ENST00000443047.2
ENST00000432561.2
ENST00000450056.2
checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
chr20_+_43160409 0.09 ENST00000372894.3
ENST00000372892.3
ENST00000372891.3
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr14_+_90863327 0.09 ENST00000356978.4
calmodulin 1 (phosphorylase kinase, delta)
chr1_-_159893507 0.09 ENST00000368096.1
transgelin 2
chr2_-_202645612 0.09 ENST00000409632.2
ENST00000410052.1
ENST00000467448.1
amyotrophic lateral sclerosis 2 (juvenile)
chr10_-_73848764 0.09 ENST00000317376.4
ENST00000412663.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr20_-_44519839 0.09 ENST00000372518.4
neuralized E3 ubiquitin protein ligase 2
chr3_-_81792780 0.09 ENST00000489715.1
glucan (1,4-alpha-), branching enzyme 1
chr19_-_15544099 0.09 ENST00000599910.2
widely interspaced zinc finger motifs
chr19_-_59070239 0.09 ENST00000595957.1
ENST00000253023.3
ubiquitin-conjugating enzyme E2M
chr1_+_43803475 0.09 ENST00000372470.3
ENST00000413998.2
myeloproliferative leukemia virus oncogene
chr5_+_135364584 0.09 ENST00000442011.2
ENST00000305126.8
transforming growth factor, beta-induced, 68kDa
chr10_-_111683183 0.09 ENST00000403138.2
ENST00000369683.1
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
chr3_-_118959716 0.09 ENST00000467604.1
ENST00000491906.1
ENST00000475803.1
ENST00000479150.1
ENST00000470111.1
ENST00000459820.1
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
chr16_+_83932684 0.09 ENST00000262430.4
malonyl-CoA decarboxylase
chr21_-_31312328 0.09 ENST00000399914.1
glutamate receptor, ionotropic, kainate 1
chr13_+_49551020 0.09 ENST00000541916.1
fibronectin type III domain containing 3A
chr14_-_45431091 0.09 ENST00000579157.1
ENST00000396128.4
ENST00000556500.1
kelch-like family member 28
chr20_-_1309809 0.09 ENST00000360779.3
syndecan binding protein (syntenin) 2
chr1_+_153004800 0.09 ENST00000392661.3
small proline-rich protein 1B
chr2_+_30370382 0.09 ENST00000402708.1
yippee-like 5 (Drosophila)
chr9_+_134165063 0.08 ENST00000372264.3
phosphatidic acid phosphatase type 2 domain containing 3
chr5_+_149569520 0.08 ENST00000230671.2
ENST00000524041.1
solute carrier family 6 (neurotransmitter transporter), member 7
chr18_-_74728998 0.08 ENST00000359645.3
ENST00000397875.3
ENST00000397869.3
ENST00000578193.1
ENST00000578873.1
ENST00000397866.4
ENST00000528160.1
ENST00000527041.1
ENST00000526111.1
ENST00000397865.5
ENST00000382582.3
myelin basic protein
chr16_+_1728257 0.08 ENST00000248098.3
ENST00000562684.1
ENST00000561516.1
ENST00000382711.5
ENST00000566742.1
hematological and neurological expressed 1-like

Network of associatons between targets according to the STRING database.

First level regulatory network of TFAP4_MSC

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.2 0.6 GO:0006218 uridine catabolic process(GO:0006218)
0.1 0.4 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 1.0 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.1 0.3 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.1 0.3 GO:0090094 metanephric cap development(GO:0072185) metanephric cap morphogenesis(GO:0072186) metanephric cap mesenchymal cell proliferation involved in metanephros development(GO:0090094)
0.1 1.1 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.3 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.1 0.2 GO:0071301 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.1 0.4 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 0.2 GO:0045062 extrathymic T cell selection(GO:0045062)
0.1 0.3 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.1 0.2 GO:0043474 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.1 0.4 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.1 0.2 GO:1904647 response to rotenone(GO:1904647)
0.1 0.3 GO:0035936 testosterone secretion(GO:0035936) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
0.1 0.2 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.1 0.2 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.1 0.2 GO:0071469 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976) cellular response to alkaline pH(GO:0071469)
0.1 0.4 GO:0030578 PML body organization(GO:0030578)
0.0 0.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.2 GO:1903490 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.0 0.2 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.5 GO:0046886 positive regulation of hormone biosynthetic process(GO:0046886)
0.0 0.1 GO:0021569 rhombomere 3 development(GO:0021569)
0.0 0.2 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.1 GO:0051685 maintenance of ER location(GO:0051685)
0.0 0.1 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.1 GO:0019085 early viral transcription(GO:0019085)
0.0 0.1 GO:0014034 neural crest cell fate commitment(GO:0014034)
0.0 0.4 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0045632 auditory receptor cell fate determination(GO:0042668) negative regulation of mechanoreceptor differentiation(GO:0045632) negative regulation of pro-B cell differentiation(GO:2000974) negative regulation of inner ear receptor cell differentiation(GO:2000981)
0.0 0.6 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0 1.0 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.1 GO:0061743 motor learning(GO:0061743)
0.0 0.4 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.3 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0 0.1 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.0 0.2 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.1 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.0 0.2 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.0 0.1 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.0 0.1 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.0 0.1 GO:1900111 positive regulation of histone H3-K9 dimethylation(GO:1900111)
0.0 0.1 GO:0043396 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) regulation of G-protein coupled receptor internalization(GO:1904020)
0.0 0.0 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.1 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.0 0.1 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.0 0.0 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.0 0.3 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.1 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.0 0.2 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.2 GO:0021564 vagus nerve development(GO:0021564)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.8 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.0 0.1 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.0 0.1 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.0 0.2 GO:0034141 positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.0 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.1 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.1 GO:1902994 regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995)
0.0 0.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.1 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.1 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.2 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.1 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 0.1 GO:0036115 fatty-acyl-CoA catabolic process(GO:0036115) malonyl-CoA metabolic process(GO:2001293)
0.0 0.1 GO:1902954 regulation of early endosome to recycling endosome transport(GO:1902954)
0.0 0.2 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.1 GO:0060168 positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.0 0.3 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.2 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.1 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.2 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.1 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.0 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.0 0.1 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.1 GO:0060437 lung growth(GO:0060437)
0.0 0.3 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.1 GO:1904209 maintenance of blood-brain barrier(GO:0035633) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 0.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.0 GO:0060151 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.0 0.1 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 0.1 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.1 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.0 0.0 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.0 0.2 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 0.1 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.0 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.0 0.2 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 0.0 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.0 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.0 0.0 GO:0070318 myoblast development(GO:0048627) positive regulation of G0 to G1 transition(GO:0070318)
0.0 0.1 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.0 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 0.2 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.1 0.4 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.4 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.9 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.6 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.5 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.3 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.6 GO:0032433 filopodium tip(GO:0032433)
0.0 0.1 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.0 0.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.1 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.2 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.0 GO:0097450 astrocyte end-foot(GO:0097450)
0.0 0.2 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.1 GO:0045160 myosin I complex(GO:0045160)
0.0 0.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.2 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.2 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.2 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.2 GO:0030914 STAGA complex(GO:0030914)
0.0 0.1 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.1 0.5 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.1 0.4 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.1 0.2 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.1 0.3 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.1 0.2 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)
0.1 0.2 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.1 0.6 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 1.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.3 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.4 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.1 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.0 0.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.2 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.9 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.2 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.1 GO:0052595 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0 0.3 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.1 GO:0070984 SET domain binding(GO:0070984)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.1 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.2 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.6 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.1 GO:0030395 lactose binding(GO:0030395)
0.0 0.1 GO:0030226 apolipoprotein receptor activity(GO:0030226)
0.0 0.4 GO:0032183 SUMO binding(GO:0032183)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.3 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.5 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.2 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.1 GO:0052642 lysophosphatidic acid phosphatase activity(GO:0052642)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.4 GO:0031489 myosin V binding(GO:0031489)
0.0 0.0 GO:0038181 bile acid receptor activity(GO:0038181)
0.0 0.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.1 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.1 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.1 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.5 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.8 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0004075 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.0 0.1 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.2 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.9 PID MYC PATHWAY C-MYC pathway
0.0 0.1 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.5 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.0 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.5 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.3 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.7 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.3 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.8 PID RHOA REG PATHWAY Regulation of RhoA activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.6 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.5 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.7 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.0 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.0 1.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.2 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.2 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex