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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for TFCP2L1

Z-value: 1.18

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Transcription factors associated with TFCP2L1

Gene Symbol Gene ID Gene Info
TFCP2L1
ENSG00000115112.7 transcription factor CP2 like 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TFCP2L1hg19_v2_chr2_-_122042770_1220427850.164.4e-01Click!

Activity profile of TFCP2L1 motif

Sorted Z-values of TFCP2L1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_31550192 4.48 ENST00000429299.2
ENST00000446745.2
LTB
lymphotoxin beta (TNF superfamily, member 3)
chr8_+_54764346 3.37 ENST00000297313.3
ENST00000344277.6
RGS20
regulator of G-protein signaling 20
chr16_-_65155833 2.87 ENST00000566827.1
ENST00000394156.3
ENST00000562998.1
CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr3_-_123411191 2.86 ENST00000354792.5
ENST00000508240.1
MYLK
myosin light chain kinase
chr7_+_151038850 2.65 ENST00000355851.4
ENST00000566856.1
ENST00000470229.1
NUB1
negative regulator of ubiquitin-like proteins 1
chr19_-_4338783 2.65 ENST00000601482.1
ENST00000600324.1
STAP2
signal transducing adaptor family member 2
chr14_+_96671016 2.54 ENST00000542454.2
ENST00000554311.1
ENST00000306005.3
ENST00000539359.1
ENST00000553811.1
BDKRB2
RP11-404P21.8
bradykinin receptor B2
Uncharacterized protein
chr19_-_4338838 2.54 ENST00000594605.1
STAP2
signal transducing adaptor family member 2
chr2_-_10588630 2.23 ENST00000234111.4
ODC1
ornithine decarboxylase 1
chr16_+_57023406 2.20 ENST00000262510.6
ENST00000308149.7
ENST00000436936.1
NLRC5
NLR family, CARD domain containing 5
chr1_+_205225319 2.17 ENST00000329800.7
TMCC2
transmembrane and coiled-coil domain family 2
chr6_+_31555045 2.06 ENST00000396101.3
ENST00000490742.1
LST1
leukocyte specific transcript 1
chr6_+_31554962 2.06 ENST00000376092.3
ENST00000376086.3
ENST00000303757.8
ENST00000376093.2
ENST00000376102.3
LST1
leukocyte specific transcript 1
chr21_-_16437255 2.02 ENST00000400199.1
ENST00000400202.1
NRIP1
nuclear receptor interacting protein 1
chr21_-_16437126 2.02 ENST00000318948.4
NRIP1
nuclear receptor interacting protein 1
chr7_+_65670186 1.86 ENST00000304842.5
ENST00000442120.1
TPST1
tyrosylprotein sulfotransferase 1
chr3_+_173302222 1.77 ENST00000361589.4
NLGN1
neuroligin 1
chr1_-_111743285 1.60 ENST00000357640.4
DENND2D
DENN/MADD domain containing 2D
chr12_-_121712313 1.60 ENST00000392474.2
CAMKK2
calcium/calmodulin-dependent protein kinase kinase 2, beta
chr22_-_37823468 1.59 ENST00000402918.2
ELFN2
extracellular leucine-rich repeat and fibronectin type III domain containing 2
chr20_+_55204351 1.32 ENST00000201031.2
TFAP2C
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr11_+_62649158 1.29 ENST00000539891.1
ENST00000536981.1
SLC3A2
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr10_-_121296045 1.26 ENST00000392865.1
RGS10
regulator of G-protein signaling 10
chr20_+_60878005 1.25 ENST00000253003.2
ADRM1
adhesion regulating molecule 1
chr12_+_7941989 1.21 ENST00000229307.4
NANOG
Nanog homeobox
chr20_-_43280361 1.19 ENST00000372874.4
ADA
adenosine deaminase
chr14_-_61124977 1.13 ENST00000554986.1
SIX1
SIX homeobox 1
chr3_-_49967292 1.11 ENST00000455683.2
MON1A
MON1 secretory trafficking family member A
chrX_-_154688276 1.09 ENST00000369445.2
F8A3
coagulation factor VIII-associated 3
chr10_+_123922941 1.06 ENST00000360561.3
TACC2
transforming, acidic coiled-coil containing protein 2
chr19_+_35629702 1.04 ENST00000351325.4
FXYD1
FXYD domain containing ion transport regulator 1
chr10_+_123923105 1.03 ENST00000368999.1
TACC2
transforming, acidic coiled-coil containing protein 2
chr16_+_84328429 1.03 ENST00000568638.1
WFDC1
WAP four-disulfide core domain 1
chr16_+_84328252 1.01 ENST00000219454.5
WFDC1
WAP four-disulfide core domain 1
chr10_+_99344071 1.00 ENST00000370647.4
ENST00000370646.4
HOGA1
4-hydroxy-2-oxoglutarate aldolase 1
chr5_+_98109322 1.00 ENST00000513185.1
RGMB
repulsive guidance molecule family member b
chr9_+_91606355 1.00 ENST00000358157.2
S1PR3
sphingosine-1-phosphate receptor 3
chr2_+_11886710 0.99 ENST00000256720.2
ENST00000441684.1
ENST00000423495.1
LPIN1
lipin 1
chr20_-_48530230 0.99 ENST00000422556.1
SPATA2
spermatogenesis associated 2
chr7_-_99756293 0.96 ENST00000316937.3
ENST00000456769.1
C7orf43
chromosome 7 open reading frame 43
chr10_+_123923205 0.95 ENST00000369004.3
ENST00000260733.3
TACC2
transforming, acidic coiled-coil containing protein 2
chr2_+_241564655 0.93 ENST00000407714.1
GPR35
G protein-coupled receptor 35
chr19_+_35630022 0.91 ENST00000589209.1
FXYD1
FXYD domain containing ion transport regulator 1
chr19_+_35630344 0.91 ENST00000455515.2
FXYD1
FXYD domain containing ion transport regulator 1
chr14_+_59104741 0.91 ENST00000395153.3
ENST00000335867.4
DACT1
dishevelled-binding antagonist of beta-catenin 1
chr5_-_131826457 0.91 ENST00000437654.1
ENST00000245414.4
IRF1
interferon regulatory factor 1
chr1_-_153538011 0.91 ENST00000368707.4
S100A2
S100 calcium binding protein A2
chr14_+_32546274 0.90 ENST00000396582.2
ARHGAP5
Rho GTPase activating protein 5
chr11_+_96123158 0.89 ENST00000332349.4
ENST00000458427.1
JRKL
jerky homolog-like (mouse)
chr17_+_7258442 0.89 ENST00000389982.4
ENST00000576060.1
ENST00000330767.4
TMEM95
transmembrane protein 95
chr3_+_63953415 0.87 ENST00000484332.1
ATXN7
ataxin 7
chr8_-_103876965 0.87 ENST00000337198.5
AZIN1
antizyme inhibitor 1
chr22_-_38484922 0.85 ENST00000428572.1
BAIAP2L2
BAI1-associated protein 2-like 2
chr9_-_130829588 0.83 ENST00000373078.4
NAIF1
nuclear apoptosis inducing factor 1
chr9_-_117150303 0.82 ENST00000312033.3
AKNA
AT-hook transcription factor
chr5_-_58652788 0.81 ENST00000405755.2
PDE4D
phosphodiesterase 4D, cAMP-specific
chr20_-_43280325 0.78 ENST00000537820.1
ADA
adenosine deaminase
chr1_-_153538292 0.77 ENST00000497140.1
ENST00000368708.3
S100A2
S100 calcium binding protein A2
chr22_+_21369316 0.76 ENST00000413302.2
ENST00000402329.3
ENST00000336296.2
ENST00000401443.1
ENST00000443995.3
P2RX6
purinergic receptor P2X, ligand-gated ion channel, 6
chr19_+_41725140 0.76 ENST00000359092.3
AXL
AXL receptor tyrosine kinase
chr17_-_80606304 0.76 ENST00000392325.4
WDR45B
WD repeat domain 45B
chr1_-_226129083 0.74 ENST00000420304.2
LEFTY2
left-right determination factor 2
chr11_-_123612319 0.73 ENST00000526252.1
ENST00000530393.1
ENST00000533463.1
ENST00000336139.4
ENST00000529691.1
ENST00000528306.1
ZNF202
zinc finger protein 202
chr12_-_58165870 0.73 ENST00000257848.7
METTL1
methyltransferase like 1
chr12_-_121342170 0.71 ENST00000353487.2
SPPL3
signal peptide peptidase like 3
chr8_-_144897138 0.70 ENST00000377533.3
SCRIB
scribbled planar cell polarity protein
chr8_-_144897549 0.70 ENST00000356994.2
ENST00000320476.3
SCRIB
scribbled planar cell polarity protein
chr5_-_160973649 0.70 ENST00000393959.1
ENST00000517547.1
GABRB2
gamma-aminobutyric acid (GABA) A receptor, beta 2
chrX_+_136648297 0.69 ENST00000287538.5
ZIC3
Zic family member 3
chr1_-_89458604 0.69 ENST00000260508.4
CCBL2
cysteine conjugate-beta lyase 2
chr1_+_9599540 0.69 ENST00000302692.6
SLC25A33
solute carrier family 25 (pyrimidine nucleotide carrier), member 33
chr8_-_145060593 0.68 ENST00000313059.5
ENST00000524918.1
ENST00000313028.7
ENST00000525773.1
PARP10
poly (ADP-ribose) polymerase family, member 10
chr2_-_233415220 0.68 ENST00000408957.3
TIGD1
tigger transposable element derived 1
chr19_-_45661995 0.65 ENST00000438936.2
NKPD1
NTPase, KAP family P-loop domain containing 1
chr14_-_69445793 0.64 ENST00000538545.2
ENST00000394419.4
ACTN1
actinin, alpha 1
chr1_-_89458415 0.64 ENST00000321792.5
ENST00000370491.3
RBMXL1
CCBL2
RNA binding motif protein, X-linked-like 1
cysteine conjugate-beta lyase 2
chr1_-_28241226 0.63 ENST00000373912.3
ENST00000373909.3
RPA2
replication protein A2, 32kDa
chr11_-_85780086 0.63 ENST00000532317.1
ENST00000528256.1
ENST00000526033.1
PICALM
phosphatidylinositol binding clathrin assembly protein
chr2_+_71295733 0.63 ENST00000443938.2
ENST00000244204.6
NAGK
N-acetylglucosamine kinase
chr1_-_89458287 0.63 ENST00000370485.2
CCBL2
cysteine conjugate-beta lyase 2
chr15_-_62352570 0.63 ENST00000261517.5
ENST00000395896.4
ENST00000395898.3
VPS13C
vacuolar protein sorting 13 homolog C (S. cerevisiae)
chr19_-_12405689 0.63 ENST00000355684.5
ZNF44
zinc finger protein 44
chr5_+_150051149 0.63 ENST00000523553.1
MYOZ3
myozenin 3
chr1_-_226129189 0.62 ENST00000366820.5
LEFTY2
left-right determination factor 2
chr7_-_2883928 0.62 ENST00000275364.3
GNA12
guanine nucleotide binding protein (G protein) alpha 12
chr2_+_202937972 0.61 ENST00000541917.1
ENST00000295844.3
AC079354.1
uncharacterized protein KIAA2012
chr2_+_71295717 0.60 ENST00000418807.3
ENST00000443872.2
NAGK
N-acetylglucosamine kinase
chr19_-_12405606 0.60 ENST00000356109.5
ZNF44
zinc finger protein 44
chr7_-_112726393 0.59 ENST00000449591.1
ENST00000449735.1
ENST00000438062.1
ENST00000424100.1
GPR85
G protein-coupled receptor 85
chr19_-_12251202 0.59 ENST00000334213.5
ZNF20
zinc finger protein 20
chr15_+_90234028 0.59 ENST00000268130.7
ENST00000560294.1
ENST00000558000.1
WDR93
WD repeat domain 93
chr1_-_89458636 0.58 ENST00000370486.1
ENST00000399794.2
CCBL2
RBMXL1
cysteine conjugate-beta lyase 2
RNA binding motif protein, X-linked-like 1
chr16_+_89574795 0.58 ENST00000268704.2
ENST00000341316.2
SPG7
spastic paraplegia 7 (pure and complicated autosomal recessive)
chr19_+_1071203 0.56 ENST00000543365.1
HMHA1
histocompatibility (minor) HA-1
chr17_-_74023291 0.56 ENST00000586740.1
EVPL
envoplakin
chr1_+_204839959 0.55 ENST00000404076.1
NFASC
neurofascin
chr3_-_52443799 0.55 ENST00000470173.1
ENST00000296288.5
BAP1
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr19_+_39421556 0.55 ENST00000407800.2
ENST00000402029.3
MRPS12
mitochondrial ribosomal protein S12
chr22_+_20119320 0.54 ENST00000334554.7
ENST00000320602.7
ENST00000405930.3
ZDHHC8
zinc finger, DHHC-type containing 8
chr6_+_149068464 0.54 ENST00000367463.4
UST
uronyl-2-sulfotransferase
chr7_-_140179276 0.54 ENST00000443720.2
ENST00000255977.2
MKRN1
makorin ring finger protein 1
chr10_+_72972281 0.54 ENST00000335350.6
UNC5B
unc-5 homolog B (C. elegans)
chr1_-_204329013 0.53 ENST00000272203.3
ENST00000414478.1
PLEKHA6
pleckstrin homology domain containing, family A member 6
chr10_-_61469837 0.53 ENST00000395348.3
SLC16A9
solute carrier family 16, member 9
chr8_-_27850141 0.52 ENST00000524352.1
SCARA5
scavenger receptor class A, member 5 (putative)
chr8_-_132052458 0.52 ENST00000377928.3
ADCY8
adenylate cyclase 8 (brain)
chr19_-_6481776 0.52 ENST00000543576.1
ENST00000590173.1
ENST00000381480.2
DENND1C
DENN/MADD domain containing 1C
chr12_-_53045948 0.51 ENST00000309680.3
KRT2
keratin 2
chr15_+_60296421 0.51 ENST00000396057.4
FOXB1
forkhead box B1
chrY_+_2803322 0.49 ENST00000383052.1
ENST00000155093.3
ENST00000449237.1
ENST00000443793.1
ZFY
zinc finger protein, Y-linked
chr8_+_55370487 0.49 ENST00000297316.4
SOX17
SRY (sex determining region Y)-box 17
chr20_+_33146510 0.49 ENST00000397709.1
MAP1LC3A
microtubule-associated protein 1 light chain 3 alpha
chr17_+_16318909 0.48 ENST00000577397.1
TRPV2
transient receptor potential cation channel, subfamily V, member 2
chr2_-_20212422 0.47 ENST00000421259.2
ENST00000407540.3
MATN3
matrilin 3
chr17_-_42452063 0.47 ENST00000588098.1
ITGA2B
integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
chr2_+_234160217 0.47 ENST00000392017.4
ENST00000347464.5
ENST00000444735.1
ENST00000373525.5
ENST00000419681.1
ATG16L1
autophagy related 16-like 1 (S. cerevisiae)
chr17_-_27278304 0.47 ENST00000577226.1
PHF12
PHD finger protein 12
chr12_+_56473910 0.47 ENST00000411731.2
ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr2_+_241544834 0.45 ENST00000319838.5
ENST00000403859.1
ENST00000438013.2
GPR35
G protein-coupled receptor 35
chrX_-_49965663 0.45 ENST00000376056.2
ENST00000376058.2
ENST00000358526.2
AKAP4
A kinase (PRKA) anchor protein 4
chr17_+_16318850 0.45 ENST00000338560.7
TRPV2
transient receptor potential cation channel, subfamily V, member 2
chr9_-_117150243 0.45 ENST00000374088.3
AKNA
AT-hook transcription factor
chr17_+_1627834 0.45 ENST00000419248.1
ENST00000418841.1
WDR81
WD repeat domain 81
chr2_+_234160340 0.44 ENST00000417017.1
ENST00000392020.4
ENST00000392018.1
ATG16L1
autophagy related 16-like 1 (S. cerevisiae)
chr5_+_95998746 0.44 ENST00000508608.1
CAST
calpastatin
chr14_-_69445968 0.43 ENST00000438964.2
ACTN1
actinin, alpha 1
chr3_+_120461484 0.43 ENST00000484715.1
ENST00000469772.1
ENST00000283875.5
ENST00000492959.1
GTF2E1
general transcription factor IIE, polypeptide 1, alpha 56kDa
chr6_-_31080336 0.43 ENST00000259870.3
C6orf15
chromosome 6 open reading frame 15
chr2_+_233415363 0.42 ENST00000409514.1
ENST00000409098.1
ENST00000409495.1
ENST00000409167.3
ENST00000409322.1
ENST00000409394.1
EIF4E2
eukaryotic translation initiation factor 4E family member 2
chr9_+_88556036 0.42 ENST00000361671.5
ENST00000416045.1
NAA35
N(alpha)-acetyltransferase 35, NatC auxiliary subunit
chr12_+_58166431 0.41 ENST00000333012.5
METTL21B
methyltransferase like 21B
chr1_-_161519579 0.40 ENST00000426740.1
FCGR3A
Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
chr11_-_128737163 0.40 ENST00000324003.3
ENST00000392665.2
KCNJ1
potassium inwardly-rectifying channel, subfamily J, member 1
chr12_+_124118366 0.40 ENST00000539994.1
ENST00000538845.1
ENST00000228955.7
ENST00000543341.2
ENST00000536375.1
GTF2H3
general transcription factor IIH, polypeptide 3, 34kDa
chr7_+_87563557 0.39 ENST00000439864.1
ENST00000412441.1
ENST00000398201.4
ENST00000265727.7
ENST00000315984.7
ENST00000398209.3
ADAM22
ADAM metallopeptidase domain 22
chr5_-_139422654 0.39 ENST00000289409.4
ENST00000358522.3
ENST00000378238.4
ENST00000289422.7
ENST00000361474.1
ENST00000545385.1
ENST00000394770.1
ENST00000541337.1
NRG2
neuregulin 2
chr1_-_207206092 0.39 ENST00000359470.5
ENST00000461135.2
C1orf116
chromosome 1 open reading frame 116
chr1_+_116654376 0.39 ENST00000369500.3
MAB21L3
mab-21-like 3 (C. elegans)
chr10_-_72545151 0.39 ENST00000299290.1
TBATA
thymus, brain and testes associated
chr17_-_1531635 0.39 ENST00000571650.1
SLC43A2
solute carrier family 43 (amino acid system L transporter), member 2
chr1_+_50571949 0.38 ENST00000357083.4
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chr20_-_57089934 0.38 ENST00000439429.1
ENST00000371149.3
APCDD1L
adenomatosis polyposis coli down-regulated 1-like
chr12_+_58166370 0.38 ENST00000300209.8
METTL21B
methyltransferase like 21B
chrX_+_49687267 0.38 ENST00000376091.3
CLCN5
chloride channel, voltage-sensitive 5
chr11_-_85779971 0.37 ENST00000393346.3
PICALM
phosphatidylinositol binding clathrin assembly protein
chr19_-_12662314 0.37 ENST00000339282.7
ENST00000596193.1
ZNF564
zinc finger protein 564
chrX_+_51075658 0.37 ENST00000356450.2
NUDT10
nudix (nucleoside diphosphate linked moiety X)-type motif 10
chr3_-_122134882 0.36 ENST00000330689.4
WDR5B
WD repeat domain 5B
chr12_-_48499591 0.36 ENST00000551330.1
ENST00000004980.5
ENST00000339976.6
ENST00000448372.1
SENP1
SUMO1/sentrin specific peptidase 1
chr12_-_110883346 0.36 ENST00000547365.1
ARPC3
actin related protein 2/3 complex, subunit 3, 21kDa
chr3_+_184080387 0.36 ENST00000455712.1
POLR2H
polymerase (RNA) II (DNA directed) polypeptide H
chr1_-_38512450 0.36 ENST00000373012.2
POU3F1
POU class 3 homeobox 1
chr12_-_48398104 0.36 ENST00000337299.6
ENST00000380518.3
COL2A1
collagen, type II, alpha 1
chr1_-_161519682 0.36 ENST00000367969.3
ENST00000443193.1
FCGR3A
Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
chr9_+_35829208 0.35 ENST00000439587.2
ENST00000377991.4
TMEM8B
transmembrane protein 8B
chrX_+_69674943 0.34 ENST00000542398.1
DLG3
discs, large homolog 3 (Drosophila)
chr1_+_113161778 0.34 ENST00000263168.3
CAPZA1
capping protein (actin filament) muscle Z-line, alpha 1
chr2_+_232646379 0.34 ENST00000410024.1
ENST00000409295.1
ENST00000409091.1
COPS7B
COP9 signalosome subunit 7B
chr2_-_161349909 0.33 ENST00000392753.3
RBMS1
RNA binding motif, single stranded interacting protein 1
chr2_+_233415488 0.33 ENST00000454501.1
EIF4E2
eukaryotic translation initiation factor 4E family member 2
chr16_+_30710462 0.33 ENST00000262518.4
ENST00000395059.2
ENST00000344771.4
SRCAP
Snf2-related CREBBP activator protein
chr6_+_73331520 0.33 ENST00000342056.2
ENST00000355194.4
KCNQ5
potassium voltage-gated channel, KQT-like subfamily, member 5
chr3_-_50605077 0.33 ENST00000426034.1
ENST00000441239.1
C3orf18
chromosome 3 open reading frame 18
chr9_+_71394945 0.32 ENST00000394264.3
FAM122A
family with sequence similarity 122A
chr11_-_96123022 0.32 ENST00000542662.1
CCDC82
coiled-coil domain containing 82
chr3_-_50605150 0.32 ENST00000357203.3
C3orf18
chromosome 3 open reading frame 18
chr17_-_27278445 0.32 ENST00000268756.3
ENST00000584685.1
PHF12
PHD finger protein 12
chr11_-_33183006 0.32 ENST00000524827.1
ENST00000323959.4
ENST00000431742.2
CSTF3
cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
chr1_+_27189631 0.32 ENST00000339276.4
SFN
stratifin
chr11_-_128737259 0.32 ENST00000440599.2
ENST00000392666.1
ENST00000324036.3
KCNJ1
potassium inwardly-rectifying channel, subfamily J, member 1
chr2_+_155554797 0.31 ENST00000295101.2
KCNJ3
potassium inwardly-rectifying channel, subfamily J, member 3
chr11_-_503521 0.31 ENST00000534797.1
RNH1
ribonuclease/angiogenin inhibitor 1
chr11_-_119293872 0.31 ENST00000524970.1
THY1
Thy-1 cell surface antigen
chr5_-_148758839 0.31 ENST00000261796.3
IL17B
interleukin 17B
chr3_+_184080790 0.30 ENST00000430783.1
POLR2H
polymerase (RNA) II (DNA directed) polypeptide H
chr18_+_21529811 0.30 ENST00000588004.1
LAMA3
laminin, alpha 3
chr17_-_33390667 0.30 ENST00000378516.2
ENST00000268850.7
ENST00000394597.2
RFFL
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr19_-_49843539 0.30 ENST00000602554.1
ENST00000358234.4
CTC-301O7.4
CTC-301O7.4
chr1_-_161600822 0.30 ENST00000534776.1
ENST00000540048.1
FCGR3B
FCGR3A
Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
chr1_-_161600990 0.30 ENST00000531221.1
FCGR3B
Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
chr20_+_9494987 0.30 ENST00000427562.2
ENST00000246070.2
LAMP5
lysosomal-associated membrane protein family, member 5
chr15_+_41136216 0.29 ENST00000562057.1
ENST00000344051.4
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr16_+_22019404 0.29 ENST00000542527.2
ENST00000569656.1
ENST00000562695.1
C16orf52
chromosome 16 open reading frame 52
chr12_+_49687425 0.29 ENST00000257860.4
PRPH
peripherin
chr1_-_161102367 0.29 ENST00000464113.1
DEDD
death effector domain containing
chr1_+_151512775 0.28 ENST00000368849.3
ENST00000392712.3
ENST00000353024.3
ENST00000368848.2
ENST00000538902.1
TUFT1
tuftelin 1
chr3_-_172166245 0.28 ENST00000427970.1
ENST00000241256.2
GHSR
growth hormone secretagogue receptor
chr7_+_87563458 0.28 ENST00000398204.4
ADAM22
ADAM metallopeptidase domain 22
chr22_-_39151463 0.27 ENST00000405510.1
ENST00000433561.1
SUN2
Sad1 and UNC84 domain containing 2
chr19_+_12721725 0.27 ENST00000446165.1
ENST00000343325.4
ENST00000458122.3
ZNF791
zinc finger protein 791
chr14_-_107170409 0.27 ENST00000390633.2
IGHV1-69
immunoglobulin heavy variable 1-69
chr20_+_44509857 0.27 ENST00000372523.1
ENST00000372520.1
ZSWIM1
zinc finger, SWIM-type containing 1
chr5_+_162864575 0.26 ENST00000512163.1
ENST00000393929.1
ENST00000340828.2
ENST00000511683.2
ENST00000510097.1
ENST00000511490.2
ENST00000510664.1
CCNG1
cyclin G1
chr11_-_116663127 0.26 ENST00000433069.1
ENST00000542499.1
APOA5
apolipoprotein A-V
chr19_+_12175504 0.26 ENST00000439326.3
ZNF844
zinc finger protein 844
chr9_+_116111794 0.26 ENST00000374183.4
BSPRY
B-box and SPRY domain containing
chr16_+_46918235 0.26 ENST00000340124.4
GPT2
glutamic pyruvate transaminase (alanine aminotransferase) 2
chr2_+_130737223 0.26 ENST00000410061.2
RAB6C
RAB6C, member RAS oncogene family
chr17_-_1532106 0.26 ENST00000301335.5
ENST00000382147.4
SLC43A2
solute carrier family 43 (amino acid system L transporter), member 2
chr12_+_14572070 0.26 ENST00000545769.1
ENST00000428217.2
ENST00000396279.2
ENST00000542514.1
ENST00000536279.1
ATF7IP
activating transcription factor 7 interacting protein

Network of associatons between targets according to the STRING database.

First level regulatory network of TFCP2L1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.1 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.7 5.4 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.7 2.0 GO:0046103 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.6 1.9 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.6 1.8 GO:0099545 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.5 0.5 GO:0061373 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373)
0.5 2.9 GO:0010734 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.5 1.4 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.4 1.6 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.4 2.2 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.3 1.0 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.3 1.3 GO:0071698 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.3 2.9 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.3 1.2 GO:0006051 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.3 4.0 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.3 1.3 GO:0060356 leucine import(GO:0060356)
0.2 1.4 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.2 0.7 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.2 2.9 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.2 0.6 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.2 1.8 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.2 1.7 GO:0001714 endodermal cell fate specification(GO:0001714)
0.2 0.9 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.2 1.2 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.2 0.7 GO:0070213 regulation of chromatin assembly(GO:0010847) negative regulation of protein import into nucleus, translocation(GO:0033159) protein auto-ADP-ribosylation(GO:0070213)
0.2 1.0 GO:0006642 triglyceride mobilization(GO:0006642)
0.2 0.9 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.1 0.5 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1 0.3 GO:0042853 L-alanine metabolic process(GO:0042851) L-alanine catabolic process(GO:0042853)
0.1 0.8 GO:2000669 negative regulation of dendritic cell apoptotic process(GO:2000669)
0.1 0.7 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.1 0.3 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.1 1.0 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.1 0.2 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.1 0.3 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.1 0.4 GO:0032214 regulation of telomere maintenance via semi-conservative replication(GO:0032213) negative regulation of telomere maintenance via semi-conservative replication(GO:0032214)
0.1 0.8 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 2.0 GO:0051764 actin crosslink formation(GO:0051764)
0.1 0.9 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.7 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1 0.5 GO:0006477 protein sulfation(GO:0006477)
0.1 0.4 GO:0015961 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.4 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 0.3 GO:1904349 regulation of small intestine smooth muscle contraction(GO:1904347) positive regulation of small intestine smooth muscle contraction(GO:1904349) small intestine smooth muscle contraction(GO:1990770) negative regulation of macrophage apoptotic process(GO:2000110)
0.1 0.2 GO:0015820 leucine transport(GO:0015820)
0.1 1.3 GO:0043248 proteasome assembly(GO:0043248)
0.1 0.6 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 0.5 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 5.5 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.1 0.8 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 0.3 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.1 0.2 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 0.3 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.2 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 0.2 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.1 0.3 GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
0.1 0.3 GO:0003343 proepicardium development(GO:0003342) septum transversum development(GO:0003343) occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.0 0.5 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 0.8 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.1 GO:0044691 tooth eruption(GO:0044691)
0.0 0.2 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.2 GO:0043366 beta selection(GO:0043366)
0.0 0.2 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.0 0.3 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0 2.2 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.0 0.9 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 4.1 GO:0050672 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
0.0 0.4 GO:0060174 limb bud formation(GO:0060174)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.0 0.7 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.4 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.2 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.4 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.2 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.0 0.5 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 1.0 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.2 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.0 0.2 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.3 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.5 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.6 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.5 GO:0051546 keratinocyte migration(GO:0051546)
0.0 0.1 GO:0038183 bile acid signaling pathway(GO:0038183)
0.0 2.8 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.2 GO:0046618 drug export(GO:0046618)
0.0 0.1 GO:0006424 glutamyl-tRNA aminoacylation(GO:0006424)
0.0 0.5 GO:0034380 high-density lipoprotein particle assembly(GO:0034380)
0.0 1.2 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.2 GO:0060613 fat pad development(GO:0060613)
0.0 0.6 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.3 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.3 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.8 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.4 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.3 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 0.9 GO:0090280 positive regulation of calcium ion import(GO:0090280)
0.0 0.6 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 3.4 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.6 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.9 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.7 GO:0010107 potassium ion import(GO:0010107)
0.0 2.0 GO:0061045 negative regulation of wound healing(GO:0061045)
0.0 0.0 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.0 0.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.6 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 0.2 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.0 0.2 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.6 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.1 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.2 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.6 GO:0010762 regulation of fibroblast migration(GO:0010762)
0.0 1.6 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 1.7 GO:0021987 cerebral cortex development(GO:0021987)
0.0 0.0 GO:0007538 primary sex determination(GO:0007538)
0.0 0.5 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 1.8 GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.0 0.5 GO:0006379 mRNA cleavage(GO:0006379)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.2 1.2 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 0.7 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.1 0.4 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.1 1.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 2.8 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 1.2 GO:0032584 growth cone membrane(GO:0032584)
0.1 0.6 GO:0097454 Schwann cell microvillus(GO:0097454)
0.1 0.4 GO:0031417 NatC complex(GO:0031417)
0.1 1.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.7 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.1 0.9 GO:0005916 fascia adherens(GO:0005916)
0.1 1.7 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 1.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.8 GO:0071439 clathrin complex(GO:0071439)
0.1 0.3 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 1.2 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.4 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.3 GO:0071203 WASH complex(GO:0071203)
0.0 0.5 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 4.6 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.3 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.6 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.2 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.8 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.4 GO:0070187 telosome(GO:0070187)
0.0 1.0 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.5 GO:0044754 autolysosome(GO:0044754)
0.0 0.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.2 GO:1990393 3M complex(GO:1990393)
0.0 0.4 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 1.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.1 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.7 GO:0030057 desmosome(GO:0030057)
0.0 2.0 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.7 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.4 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.6 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.5 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 1.6 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 2.3 GO:0001650 fibrillar center(GO:0001650)
0.0 0.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 1.0 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.3 GO:0042627 chylomicron(GO:0042627)
0.0 0.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0004947 bradykinin receptor activity(GO:0004947)
0.6 1.9 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.4 1.2 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.3 2.9 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.2 1.0 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.2 0.7 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.2 4.0 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.2 0.5 GO:0070051 fibrinogen binding(GO:0070051)
0.2 1.3 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 1.0 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.1 0.4 GO:0070052 collagen V binding(GO:0070052)
0.1 0.9 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.1 0.7 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 2.0 GO:0004000 adenosine deaminase activity(GO:0004000)
0.1 0.9 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.3 GO:0098808 mRNA cap binding(GO:0098808)
0.1 0.6 GO:0051373 FATZ binding(GO:0051373)
0.1 0.7 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.6 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.1 0.7 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.1 1.6 GO:0019864 IgG binding(GO:0019864)
0.1 1.0 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 4.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 1.3 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.3 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.1 1.0 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.1 1.7 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.4 GO:0052846 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.1 0.4 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 0.4 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.8 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 0.8 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 0.8 GO:0019826 oxygen sensor activity(GO:0019826)
0.1 1.2 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 0.3 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 0.8 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 1.7 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.3 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.1 GO:0052595 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0 1.1 GO:0017166 vinculin binding(GO:0017166)
0.0 2.9 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.8 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.2 GO:0001855 complement component C4b binding(GO:0001855)
0.0 0.7 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.7 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.8 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.3 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.6 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.2 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.0 1.2 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.3 GO:0035473 lipase binding(GO:0035473) lipoprotein lipase activator activity(GO:0060230)
0.0 1.1 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.3 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.8 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.3 GO:0034235 GPI anchor binding(GO:0034235)
0.0 1.6 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.3 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.0 2.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.5 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 1.9 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.4 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0038181 bile acid receptor activity(GO:0038181)
0.0 1.8 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.1 GO:0004818 glutamate-tRNA ligase activity(GO:0004818)
0.0 0.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 2.2 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.4 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.2 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.2 GO:0031013 troponin I binding(GO:0031013)
0.0 0.5 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 2.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.7 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.5 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.4 GO:0043495 protein anchor(GO:0043495)
0.0 0.9 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.0 GO:0052870 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 3.2 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.0 0.6 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.9 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.2 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.2 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.1 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 2.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.0 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 6.8 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 3.7 ST G ALPHA I PATHWAY G alpha i Pathway
0.1 3.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 1.6 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 2.9 PID AURORA B PATHWAY Aurora B signaling
0.0 1.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.8 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.8 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.2 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.9 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.7 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 1.0 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 2.2 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.5 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.1 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.5 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.6 PID FANCONI PATHWAY Fanconi anemia pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 2.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 2.0 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 2.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 3.9 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 0.6 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 1.2 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 2.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 1.0 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 1.1 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.9 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 2.2 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.8 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.5 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 1.0 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.9 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.8 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.6 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.7 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.4 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.5 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 1.0 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.5 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.8 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.2 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.3 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.4 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.9 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 1.1 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.2 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport