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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for TFEC_MITF_ARNTL_BHLHE41

Z-value: 0.90

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Transcription factors associated with TFEC_MITF_ARNTL_BHLHE41

Gene Symbol Gene ID Gene Info
ENSG00000105967.11 transcription factor EC
ENSG00000187098.10 melanocyte inducing transcription factor
ENSG00000133794.13 aryl hydrocarbon receptor nuclear translocator like
ENSG00000123095.5 basic helix-loop-helix family member e41

Activity-expression correlation:

Activity profile of TFEC_MITF_ARNTL_BHLHE41 motif

Sorted Z-values of TFEC_MITF_ARNTL_BHLHE41 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_11866034 3.78 ENST00000376590.3
methylenetetrahydrofolate reductase (NAD(P)H)
chr10_-_105452917 2.59 ENST00000427662.2
SH3 and PX domains 2A
chr11_+_67159416 2.12 ENST00000307980.2
ENST00000544620.1
RAD9 homolog A (S. pombe)
chr1_+_11866207 2.11 ENST00000312413.6
ENST00000346436.6
chloride channel, voltage-sensitive 6
chr1_+_11866270 2.11 ENST00000376497.3
ENST00000376487.3
ENST00000376496.3
chloride channel, voltage-sensitive 6
chr17_-_47841485 2.10 ENST00000506156.1
ENST00000240364.2
family with sequence similarity 117, member A
chr7_-_27205136 1.83 ENST00000396345.1
ENST00000343483.6
homeobox A9
chr5_+_41904431 1.82 ENST00000381647.2
chromosome 5 open reading frame 51
chr12_-_122751002 1.78 ENST00000267199.4
vacuolar protein sorting 33 homolog A (S. cerevisiae)
chr15_+_41913690 1.77 ENST00000563576.1
MGA, MAX dimerization protein
chr10_-_14050522 1.64 ENST00000342409.2
FERM domain containing 4A
chr17_-_7137582 1.60 ENST00000575756.1
ENST00000575458.1
dishevelled segment polarity protein 2
chr6_+_7107999 1.52 ENST00000491191.1
ENST00000379938.2
ENST00000471433.1
ras responsive element binding protein 1
chr5_-_172198190 1.49 ENST00000239223.3
dual specificity phosphatase 1
chr20_+_58515417 1.49 ENST00000360816.3
family with sequence similarity 217, member B
chr7_-_27135591 1.49 ENST00000343060.4
ENST00000355633.5
homeobox A1
chr17_-_7137857 1.46 ENST00000005340.5
dishevelled segment polarity protein 2
chr9_-_131709858 1.39 ENST00000372586.3
dolichol kinase
chr13_+_42846272 1.37 ENST00000025301.2
A kinase (PRKA) anchor protein 11
chr10_+_99258625 1.33 ENST00000370664.3
ubiquitin domain containing 1
chr1_-_42921915 1.32 ENST00000372565.3
ENST00000433602.2
zinc finger, MYND-type containing 12
chr7_-_27183263 1.27 ENST00000222726.3
homeobox A5
chr8_-_71581377 1.26 ENST00000276590.4
ENST00000522447.1
lactamase, beta 2
chr6_+_87865262 1.26 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
zinc finger protein 292
chr10_-_32217717 1.23 ENST00000396144.4
ENST00000375245.4
ENST00000344936.2
ENST00000375250.5
Rho GTPase activating protein 12
chr22_+_40573921 1.20 ENST00000454349.2
ENST00000335727.9
trinucleotide repeat containing 6B
chr14_-_20929624 1.16 ENST00000398020.4
ENST00000250489.4
transmembrane protein 55B
chr1_-_154531095 1.16 ENST00000292211.4
ubiquitin-conjugating enzyme E2Q family member 1
chr2_-_176866978 1.14 ENST00000392540.2
ENST00000409660.1
ENST00000544803.1
ENST00000272748.4
KIAA1715
chr2_+_220042933 1.10 ENST00000430297.2
family with sequence similarity 134, member A
chr12_+_12878829 1.09 ENST00000326765.6
apolipoprotein L domain containing 1
chr19_+_32836499 1.09 ENST00000311921.4
ENST00000544431.1
ENST00000355898.5
zinc finger protein 507
chr10_+_46222648 1.09 ENST00000336378.4
ENST00000540872.1
ENST00000537517.1
ENST00000374362.2
ENST00000359860.4
ENST00000420848.1
family with sequence similarity 21, member C
chr3_-_122512619 1.04 ENST00000383659.1
ENST00000306103.2
HSPB (heat shock 27kDa) associated protein 1
chr2_-_26101374 1.04 ENST00000435504.4
additional sex combs like 2 (Drosophila)
chr6_-_84937314 1.04 ENST00000257766.4
ENST00000403245.3
KIAA1009
chr16_+_30960375 1.03 ENST00000318663.4
ENST00000566237.1
ENST00000562699.1
ORAI calcium release-activated calcium modulator 3
chr11_+_7534999 1.03 ENST00000528947.1
ENST00000299492.4
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr4_-_47465666 1.01 ENST00000381571.4
COMM domain containing 8
chr7_-_27196267 1.00 ENST00000242159.3
homeobox A7
chr14_-_68283291 0.99 ENST00000555452.1
ENST00000347230.4
zinc finger, FYVE domain containing 26
chr17_-_35969409 0.99 ENST00000394378.2
ENST00000585472.1
ENST00000591288.1
ENST00000502449.2
ENST00000345615.4
ENST00000346661.4
ENST00000585689.1
ENST00000339208.6
synergin, gamma
chr8_-_126104055 0.98 ENST00000318410.7
KIAA0196
chr8_-_126103969 0.98 ENST00000517845.1
KIAA0196
chr19_-_36545128 0.97 ENST00000538849.1
THAP domain containing 8
chr19_-_41256207 0.96 ENST00000598485.2
ENST00000470681.1
ENST00000339153.3
ENST00000598729.1
chromosome 19 open reading frame 54
chr6_-_43337180 0.95 ENST00000318149.3
ENST00000361428.2
zinc finger protein 318
chr14_+_77564440 0.91 ENST00000361786.2
ENST00000555437.1
ENST00000555611.1
ENST00000554658.1
CLOCK-interacting pacemaker
chrX_+_149737046 0.91 ENST00000370396.2
ENST00000542741.1
ENST00000543350.1
ENST00000424519.1
ENST00000413012.2
myotubularin 1
chrX_+_101975619 0.90 ENST00000457056.1
basic helix-loop-helix domain containing, class B, 9
chrX_+_101975643 0.90 ENST00000361229.4
basic helix-loop-helix domain containing, class B, 9
chr1_+_15853308 0.89 ENST00000375838.1
ENST00000375847.3
ENST00000375849.1
DnaJ (Hsp40) homolog, subfamily C, member 16
chr9_+_74526384 0.88 ENST00000334731.2
ENST00000377031.3
chromosome 9 open reading frame 85
chr10_-_93392811 0.86 ENST00000238994.5
protein phosphatase 1, regulatory subunit 3C
chr10_+_70480963 0.83 ENST00000265872.6
ENST00000535016.1
ENST00000538031.1
ENST00000543719.1
ENST00000539539.1
ENST00000543225.1
ENST00000536012.1
ENST00000494903.2
cell division cycle and apoptosis regulator 1
chr12_-_123849374 0.83 ENST00000602398.1
ENST00000602750.1
strawberry notch homolog 1 (Drosophila)
chr1_+_221051699 0.83 ENST00000366903.6
H2.0-like homeobox
chr16_+_76587314 0.79 ENST00000563764.1
Uncharacterized protein
chr12_-_110434183 0.79 ENST00000360185.4
ENST00000354574.4
ENST00000338373.5
ENST00000343646.5
ENST00000356259.4
ENST00000553118.1
G protein-coupled receptor kinase interacting ArfGAP 2
chr8_+_133787586 0.78 ENST00000395379.1
ENST00000395386.2
ENST00000337920.4
PHD finger protein 20-like 1
chr10_+_51827648 0.76 ENST00000351071.6
ENST00000314664.7
ENST00000282633.5
family with sequence similarity 21, member A
chr20_+_18118486 0.75 ENST00000432901.3
PET117 homolog (S. cerevisiae)
chr17_-_21156578 0.74 ENST00000399011.2
ENST00000468196.1
chromosome 17 open reading frame 103
chr3_+_112280857 0.74 ENST00000492406.1
ENST00000468642.1
solute carrier family 35, member A5
chr20_+_18118703 0.74 ENST00000464792.1
CSRP2 binding protein
chr12_+_122064673 0.73 ENST00000537188.1
ORAI calcium release-activated calcium modulator 1
chr11_+_18344106 0.73 ENST00000534641.1
ENST00000525831.1
ENST00000265963.4
general transcription factor IIH, polypeptide 1, 62kDa
chr19_+_6464502 0.72 ENST00000308243.7
crumbs homolog 3 (Drosophila)
chr12_+_51632666 0.72 ENST00000604900.1
DAZ associated protein 2
chr2_+_233562015 0.71 ENST00000427233.1
ENST00000373566.3
ENST00000373563.4
ENST00000428883.1
ENST00000456491.1
ENST00000409480.1
ENST00000421433.1
ENST00000425040.1
ENST00000430720.1
ENST00000409547.1
ENST00000423659.1
ENST00000409196.3
ENST00000409451.3
ENST00000429187.1
ENST00000440945.1
GRB10 interacting GYF protein 2
chr19_+_1275917 0.70 ENST00000469144.1
chromosome 19 open reading frame 24
chr13_-_52027134 0.70 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
integrator complex subunit 6
chrX_+_146993534 0.70 ENST00000334557.6
ENST00000439526.2
ENST00000370475.4
fragile X mental retardation 1
chr11_+_95523823 0.69 ENST00000538658.1
centrosomal protein 57kDa
chr12_+_2986359 0.68 ENST00000538636.1
ENST00000461997.2
ENST00000489288.2
ENST00000366285.2
ENST00000538700.1
RAD9-HUS1-RAD1 interacting nuclear orphan 1
chr19_-_40854417 0.68 ENST00000582006.1
ENST00000582783.1
chromosome 19 open reading frame 47
chr2_+_148778570 0.67 ENST00000407073.1
methyl-CpG binding domain protein 5
chrX_+_146993449 0.66 ENST00000218200.8
ENST00000370471.3
ENST00000370477.1
fragile X mental retardation 1
chr13_-_79233314 0.66 ENST00000282003.6
ring finger protein 219
chr17_+_1627834 0.65 ENST00000419248.1
ENST00000418841.1
WD repeat domain 81
chr11_-_18343669 0.64 ENST00000396253.3
ENST00000349215.3
ENST00000438420.2
Hermansky-Pudlak syndrome 5
chr2_-_211036051 0.64 ENST00000418791.1
ENST00000452086.1
ENST00000281772.9
KAT8 regulatory NSL complex subunit 1-like
chr2_+_172864490 0.64 ENST00000315796.4
methionyl aminopeptidase type 1D (mitochondrial)
chr16_+_2570340 0.64 ENST00000568263.1
ENST00000293971.6
ENST00000302956.4
ENST00000413459.3
ENST00000566706.1
ENST00000569879.1
amidohydrolase domain containing 2
chr12_-_122750957 0.64 ENST00000451053.2
vacuolar protein sorting 33 homolog A (S. cerevisiae)
chr11_-_60719213 0.63 ENST00000227880.3
solute carrier family 15 (oligopeptide transporter), member 3
chr6_+_7107830 0.63 ENST00000379933.3
ras responsive element binding protein 1
chr17_+_48450575 0.62 ENST00000338165.4
ENST00000393271.2
ENST00000511519.2
essential meiotic structure-specific endonuclease 1
chr2_+_46926326 0.62 ENST00000394861.2
suppressor of cytokine signaling 5
chr11_+_118938485 0.60 ENST00000300793.6
vacuolar protein sorting 11 homolog (S. cerevisiae)
chr7_-_155089251 0.60 ENST00000609974.1
AC144652.1
chr11_+_63706444 0.60 ENST00000377793.4
ENST00000456907.2
ENST00000539656.1
N(alpha)-acetyltransferase 40, NatD catalytic subunit
chr1_+_42922173 0.60 ENST00000455780.1
ENST00000372560.3
ENST00000372561.3
ENST00000372556.3
phosphopantothenoylcysteine synthetase
chr19_-_5340730 0.60 ENST00000372412.4
ENST00000357368.4
ENST00000262963.6
ENST00000348075.2
ENST00000353284.2
protein tyrosine phosphatase, receptor type, S
chr12_-_63328817 0.60 ENST00000228705.6
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr17_-_1733114 0.60 ENST00000305513.7
SET and MYND domain containing 4
chr2_+_85981008 0.60 ENST00000306279.3
atonal homolog 8 (Drosophila)
chr14_+_38677123 0.59 ENST00000267377.2
somatostatin receptor 1
chr12_+_50898881 0.58 ENST00000301180.5
DIP2 disco-interacting protein 2 homolog B (Drosophila)
chr9_+_133454943 0.58 ENST00000319725.9
far upstream element (FUSE) binding protein 3
chr1_-_68962782 0.58 ENST00000456315.2
DEP domain containing 1
chr16_-_68269971 0.58 ENST00000565858.1
epithelial splicing regulatory protein 2
chr19_-_49137790 0.58 ENST00000599385.1
D site of albumin promoter (albumin D-box) binding protein
chr5_+_172483347 0.57 ENST00000522692.1
ENST00000296953.2
ENST00000540014.1
ENST00000520420.1
CREB3 regulatory factor
chr12_+_57916466 0.56 ENST00000355673.3
methyl-CpG binding domain protein 6
chr14_-_39901618 0.56 ENST00000554932.1
ENST00000298097.7
F-box protein 33
chr12_-_110434021 0.56 ENST00000355312.3
ENST00000551209.1
ENST00000550186.1
G protein-coupled receptor kinase interacting ArfGAP 2
chr12_+_90102729 0.56 ENST00000605386.1
long intergenic non-protein coding RNA 936
chr16_-_58718611 0.56 ENST00000564100.1
ENST00000570101.1
solute carrier family 38, member 7
chr13_+_49684445 0.55 ENST00000398316.3
fibronectin type III domain containing 3A
chr1_-_68962805 0.55 ENST00000370966.5
DEP domain containing 1
chr7_+_116593433 0.55 ENST00000323984.3
ENST00000393449.1
suppression of tumorigenicity 7
chr3_+_134205000 0.54 ENST00000512894.1
ENST00000513612.2
ENST00000606977.1
centrosomal protein 63kDa
chr16_+_68119247 0.53 ENST00000575270.1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr6_+_7108210 0.53 ENST00000467782.1
ENST00000334984.6
ENST00000349384.6
ras responsive element binding protein 1
chr10_+_102759045 0.53 ENST00000370220.1
leucine zipper, putative tumor suppressor 2
chrX_+_100663243 0.53 ENST00000316594.5
heterogeneous nuclear ribonucleoprotein H2 (H')
chr17_+_40719073 0.53 ENST00000435881.2
ENST00000246912.4
ENST00000346833.4
ENST00000591024.1
MLX, MAX dimerization protein
chr7_+_116593568 0.52 ENST00000446490.1
suppression of tumorigenicity 7
chr3_+_134204881 0.52 ENST00000511574.1
ENST00000337090.3
ENST00000383229.3
centrosomal protein 63kDa
chrX_-_107979616 0.52 ENST00000372129.2
insulin receptor substrate 4
chr4_-_76439483 0.51 ENST00000380840.2
ENST00000513257.1
ENST00000507014.1
ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
chr2_-_133427767 0.51 ENST00000397463.2
LY6/PLAUR domain containing 1
chr8_+_98656336 0.51 ENST00000336273.3
metadherin
chr12_-_90102594 0.51 ENST00000428670.3
ATPase, Ca++ transporting, plasma membrane 1
chr11_+_107879459 0.51 ENST00000393094.2
cullin 5
chr2_-_183903133 0.51 ENST00000361354.4
NCK-associated protein 1
chr1_+_92414952 0.50 ENST00000449584.1
ENST00000427104.1
ENST00000355011.3
ENST00000448194.1
ENST00000426141.1
ENST00000450792.1
ENST00000548992.1
ENST00000552654.1
ENST00000457265.1
bromodomain, testis-specific
chr17_+_65821636 0.50 ENST00000544778.2
bromodomain PHD finger transcription factor
chr19_+_14544099 0.50 ENST00000242783.6
ENST00000586557.1
ENST00000590097.1
protein kinase N1
chr9_+_131799213 0.50 ENST00000358369.4
ENST00000406926.2
ENST00000277475.5
ENST00000450073.1
family with sequence similarity 73, member B
chr8_-_82754427 0.50 ENST00000353788.4
ENST00000520618.1
ENST00000518183.1
ENST00000396330.2
ENST00000519119.1
ENST00000345957.4
sorting nexin 16
chr4_+_1340986 0.49 ENST00000511216.1
ENST00000389851.4
UV-stimulated scaffold protein A
chr10_+_22610124 0.49 ENST00000376663.3
BMI1 polycomb ring finger oncogene
chr6_-_7313381 0.48 ENST00000489567.1
ENST00000479365.1
ENST00000462112.1
ENST00000397511.2
ENST00000534851.1
ENST00000474597.1
ENST00000244763.4
signal sequence receptor, alpha
chr19_-_36545649 0.48 ENST00000292894.1
THAP domain containing 8
chrX_+_118108601 0.48 ENST00000371628.3
LON peptidase N-terminal domain and ring finger 3
chr20_-_58515344 0.47 ENST00000370996.3
protein phosphatase 1, regulatory subunit 3D
chr6_+_7590413 0.47 ENST00000342415.5
small nuclear ribonucleoprotein 48kDa (U11/U12)
chrX_-_34675391 0.47 ENST00000275954.3
transmembrane protein 47
chr1_+_10092890 0.47 ENST00000253251.8
ENST00000377157.3
ubiquitination factor E4B
chr17_-_6915646 0.47 ENST00000574377.1
ENST00000399541.2
ENST00000399540.2
ENST00000575727.1
ENST00000573939.1
Uncharacterized protein
chr19_-_49843539 0.46 ENST00000602554.1
ENST00000358234.4
CTC-301O7.4
chr16_-_70719925 0.46 ENST00000338779.6
metastasis suppressor 1-like
chr19_+_41305406 0.46 ENST00000406058.2
ENST00000593726.1
egl-9 family hypoxia-inducible factor 2
chr7_+_100271355 0.46 ENST00000436220.1
ENST00000424361.1
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr7_-_27224842 0.45 ENST00000517402.1
homeobox A11
chr8_-_13134045 0.45 ENST00000512044.2
deleted in liver cancer 1
chr20_-_44519839 0.45 ENST00000372518.4
neuralized E3 ubiquitin protein ligase 2
chr7_-_27224795 0.44 ENST00000006015.3
homeobox A11
chr12_-_76953573 0.44 ENST00000549646.1
ENST00000550628.1
ENST00000553139.1
ENST00000261183.3
ENST00000393250.4
oxysterol binding protein-like 8
chr6_-_80657292 0.44 ENST00000369816.4
ELOVL fatty acid elongase 4
chr3_-_57678772 0.43 ENST00000311128.5
DENN/MADD domain containing 6A
chr2_+_46926048 0.43 ENST00000306503.5
suppressor of cytokine signaling 5
chr22_-_36903101 0.43 ENST00000397224.4
FAD-dependent oxidoreductase domain containing 2
chr10_-_31320840 0.43 ENST00000375311.1
zinc finger protein 438
chr19_+_5681153 0.43 ENST00000579559.1
ENST00000577222.1
hydroxysteroid (11-beta) dehydrogenase 1-like
ribosomal protein L36
chr19_-_6424783 0.43 ENST00000398148.3
KH-type splicing regulatory protein
chr4_-_149363662 0.43 ENST00000355292.3
ENST00000358102.3
nuclear receptor subfamily 3, group C, member 2
chr12_-_2986107 0.43 ENST00000359843.3
ENST00000342628.2
ENST00000361953.3
forkhead box M1
chr2_+_75061108 0.42 ENST00000290573.2
hexokinase 2
chr12_+_14518598 0.42 ENST00000261168.4
ENST00000538511.1
ENST00000545723.1
ENST00000543189.1
ENST00000536444.1
activating transcription factor 7 interacting protein
chr7_+_100271446 0.42 ENST00000419828.1
ENST00000427895.1
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr2_-_148778323 0.42 ENST00000440042.1
ENST00000535373.1
ENST00000540442.1
ENST00000536575.1
origin recognition complex, subunit 4
chr12_+_28343365 0.42 ENST00000545336.1
coiled-coil domain containing 91
chr3_-_126076264 0.42 ENST00000296233.3
Kruppel-like factor 15
chr5_+_139493665 0.42 ENST00000331327.3
purine-rich element binding protein A
chr9_-_135819987 0.42 ENST00000298552.3
ENST00000403810.1
tuberous sclerosis 1
chr5_-_131892501 0.42 ENST00000450655.1
interleukin 5 (colony-stimulating factor, eosinophil)
chr18_+_56530794 0.41 ENST00000590285.1
ENST00000586085.1
ENST00000589288.1
zinc finger protein 532
chr5_-_132299290 0.41 ENST00000378595.3
AF4/FMR2 family, member 4
chr16_+_68119440 0.41 ENST00000346183.3
ENST00000329524.4
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr17_+_55163075 0.41 ENST00000571629.1
ENST00000570423.1
ENST00000575186.1
ENST00000573085.1
ENST00000572814.1
A kinase (PRKA) anchor protein 1
chr17_-_46688334 0.41 ENST00000239165.7
homeobox B7
chr2_-_220042825 0.41 ENST00000409789.1
cyclin Pas1/PHO80 domain containing 1
chr1_-_202896310 0.40 ENST00000367261.3
kelch-like family member 12
chrX_+_118108571 0.40 ENST00000304778.7
LON peptidase N-terminal domain and ring finger 3
chr11_+_7597639 0.39 ENST00000533792.1
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr10_+_102756800 0.39 ENST00000370223.3
leucine zipper, putative tumor suppressor 2
chr1_+_42921761 0.39 ENST00000372562.1
phosphopantothenoylcysteine synthetase
chr15_+_91260552 0.39 ENST00000355112.3
ENST00000560509.1
Bloom syndrome, RecQ helicase-like
chr8_-_54755789 0.38 ENST00000359530.2
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr1_+_222885884 0.38 ENST00000340934.5
BRO1 domain and CAAX motif containing
chr12_-_111358372 0.38 ENST00000548438.1
ENST00000228841.8
myosin, light chain 2, regulatory, cardiac, slow
chr2_+_27805880 0.38 ENST00000379717.1
ENST00000355467.4
ENST00000556601.1
ENST00000416005.2
zinc finger protein 512
chr8_+_71581565 0.38 ENST00000408926.3
ENST00000520030.1
XK, Kell blood group complex subunit-related family, member 9
chr6_+_117803797 0.38 ENST00000296955.8
ENST00000368503.4
ENST00000338728.5
discoidin, CUB and LCCL domain containing 1
chr16_+_68119324 0.37 ENST00000349223.5
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr1_+_150254936 0.37 ENST00000447007.1
ENST00000369095.1
ENST00000369094.1
chromosome 1 open reading frame 51
chr19_+_41305085 0.37 ENST00000303961.4
egl-9 family hypoxia-inducible factor 2
chr3_+_134204551 0.37 ENST00000332047.5
ENST00000354446.3
centrosomal protein 63kDa
chr5_-_133706695 0.36 ENST00000521755.1
ENST00000523054.1
ENST00000435240.2
ENST00000609654.1
ENST00000536186.1
ENST00000609383.1
cyclin-dependent kinase-like 3
chr9_+_706842 0.36 ENST00000382293.3
KN motif and ankyrin repeat domains 1
chr6_+_139349817 0.36 ENST00000367660.3
ABRA C-terminal like
chr8_+_98656693 0.36 ENST00000519934.1
metadherin
chr19_-_51143075 0.36 ENST00000600079.1
ENST00000593901.1
synaptotagmin III
chr9_-_126030817 0.36 ENST00000348403.5
ENST00000447404.2
ENST00000360998.3
spermatid perinuclear RNA binding protein
chr9_-_103115185 0.36 ENST00000374902.4
testis expressed 10
chr4_-_76439596 0.36 ENST00000451788.1
ENST00000512706.1
ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
chr11_-_19263145 0.36 ENST00000532666.1
ENST00000527884.1
E2F transcription factor 8

Network of associatons between targets according to the STRING database.

First level regulatory network of TFEC_MITF_ARNTL_BHLHE41

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.1 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.7 3.4 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.7 2.7 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.4 2.6 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.4 1.3 GO:0060435 bronchiole development(GO:0060435)
0.3 0.3 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.3 0.9 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.3 2.0 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.3 1.4 GO:1901252 regulation of intracellular transport of viral material(GO:1901252) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.2 1.9 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.2 0.6 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.2 1.4 GO:0098535 de novo centriole assembly(GO:0098535)
0.2 0.6 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
0.2 0.6 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.2 0.6 GO:0015817 histidine transport(GO:0015817) L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.2 0.7 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.2 0.2 GO:2000506 negative regulation of energy homeostasis(GO:2000506)
0.2 2.9 GO:0042118 endothelial cell activation(GO:0042118)
0.2 1.4 GO:0046465 dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.1 0.4 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.1 1.4 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.1 2.2 GO:0002115 store-operated calcium entry(GO:0002115)
0.1 0.5 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.1 0.4 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.1 0.4 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.1 0.6 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.1 0.4 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.1 0.6 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.1 0.8 GO:1904925 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.1 1.3 GO:0070459 prolactin secretion(GO:0070459)
0.1 0.4 GO:0002086 diaphragm contraction(GO:0002086)
0.1 0.7 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.1 0.3 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
0.1 0.3 GO:1903567 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.1 0.6 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.1 0.4 GO:0051029 rRNA transport(GO:0051029)
0.1 3.8 GO:0006884 cell volume homeostasis(GO:0006884)
0.1 0.3 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.1 1.1 GO:0045656 negative regulation of monocyte differentiation(GO:0045656)
0.1 0.4 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.1 0.3 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.1 0.3 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1 0.3 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.1 1.7 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.1 0.5 GO:0060620 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.1 0.3 GO:0010157 response to chlorate(GO:0010157)
0.1 0.3 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.1 0.1 GO:0007521 muscle cell fate determination(GO:0007521)
0.1 0.5 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.1 0.5 GO:0000189 MAPK import into nucleus(GO:0000189) regulation of Golgi inheritance(GO:0090170)
0.1 2.6 GO:0030220 platelet formation(GO:0030220)
0.1 0.2 GO:0043686 co-translational protein modification(GO:0043686)
0.1 0.5 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 1.3 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.1 0.4 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.1 0.4 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.1 0.9 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.4 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.3 GO:0042823 pyridoxal phosphate biosynthetic process(GO:0042823)
0.1 0.2 GO:0044209 AMP salvage(GO:0044209)
0.1 1.1 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.1 0.9 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 0.4 GO:0044806 G-quadruplex DNA unwinding(GO:0044806) cellular response to camptothecin(GO:0072757)
0.1 1.0 GO:0007501 mesodermal cell fate specification(GO:0007501)
0.1 0.5 GO:0071386 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.1 0.2 GO:0021823 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.1 2.3 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 0.2 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 0.2 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 0.1 GO:0072268 pattern specification involved in metanephros development(GO:0072268)
0.1 0.4 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.4 GO:1901314 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.1 0.6 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.1 1.7 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.1 0.2 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 0.3 GO:0006041 glucosamine metabolic process(GO:0006041)
0.1 0.2 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.0 1.8 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.3 GO:0030242 pexophagy(GO:0030242)
0.0 0.2 GO:0035978 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
0.0 0.4 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.4 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 0.2 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.0 0.5 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.4 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.5 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 0.2 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.2 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.2 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.0 0.2 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.0 0.4 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.0 1.2 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.1 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.0 0.2 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.0 0.4 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.2 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.4 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.8 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.2 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.1 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.0 0.1 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.0 0.3 GO:0034033 nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.0 0.4 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.5 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.7 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.1 GO:0009644 response to high light intensity(GO:0009644) cellular response to light intensity(GO:0071484)
0.0 0.4 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.5 GO:0007379 segment specification(GO:0007379)
0.0 0.1 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.0 0.1 GO:0009227 nucleotide-sugar catabolic process(GO:0009227)
0.0 0.1 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:0070827 chromatin maintenance(GO:0070827)
0.0 0.2 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.1 GO:0042636 negative regulation of hair cycle(GO:0042636)
0.0 0.3 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.9 GO:0070987 error-free translesion synthesis(GO:0070987)
0.0 0.2 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.1 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.1 GO:1903566 ciliary basal body organization(GO:0032053) positive regulation of protein localization to cilium(GO:1903566)
0.0 0.1 GO:0007343 egg activation(GO:0007343)
0.0 0.6 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.3 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.7 GO:0016180 snRNA processing(GO:0016180)
0.0 0.3 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.5 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.5 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.7 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.1 GO:1904760 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.0 0.2 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
0.0 0.4 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.0 0.1 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.1 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.5 GO:0003222 ventricular trabecula myocardium morphogenesis(GO:0003222)
0.0 2.5 GO:0043297 apical junction assembly(GO:0043297)
0.0 0.3 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0 0.4 GO:0014029 neural crest formation(GO:0014029)
0.0 0.1 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.1 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.0 0.2 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:2000546 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.0 0.2 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.1 GO:0071105 response to interleukin-11(GO:0071105)
0.0 0.0 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.2 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.2 GO:0097106 postsynaptic density organization(GO:0097106) postsynaptic density assembly(GO:0097107) gephyrin clustering involved in postsynaptic density assembly(GO:0097116) neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 0.0 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609)
0.0 1.3 GO:0002011 morphogenesis of an epithelial sheet(GO:0002011)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.6 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.0 0.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.5 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.5 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.9 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 0.2 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.5 GO:1905144 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 0.2 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.0 0.1 GO:0005985 sucrose metabolic process(GO:0005985)
0.0 0.4 GO:0061318 renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.3 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.2 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.1 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.1 GO:0015811 L-cystine transport(GO:0015811)
0.0 0.2 GO:1902570 protein localization to nucleolus(GO:1902570)
0.0 0.1 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0 0.2 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.0 0.5 GO:0002021 response to dietary excess(GO:0002021)
0.0 0.1 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.4 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 1.0 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.6 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.4 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.4 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.0 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.3 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.1 GO:0060539 diaphragm development(GO:0060539)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.3 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.4 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.1 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.0 0.7 GO:0034724 DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-independent nucleosome organization(GO:0034724)
0.0 0.1 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.0 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.0 0.2 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.1 GO:0032264 IMP salvage(GO:0032264)
0.0 0.1 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.0 GO:0051039 histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.0 0.1 GO:0003214 negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865) cardiac left ventricle morphogenesis(GO:0003214)
0.0 0.8 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.8 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.1 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.1 GO:0002097 tRNA wobble base modification(GO:0002097)
0.0 0.6 GO:0097484 dendrite extension(GO:0097484)
0.0 0.0 GO:1900075 regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
0.0 0.2 GO:0015816 glycine transport(GO:0015816)
0.0 0.1 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.0 GO:0006059 hexitol metabolic process(GO:0006059)
0.0 0.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.0 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.2 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.2 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.0 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.0 0.3 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 0.0 GO:0061582 intestinal epithelial cell migration(GO:0061582)
0.0 0.0 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.3 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.0 GO:1900195 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428) positive regulation of oocyte maturation(GO:1900195) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.0 0.1 GO:1902903 regulation of fibril organization(GO:1902903)
0.0 0.1 GO:0070980 biphenyl catabolic process(GO:0070980)
0.0 0.2 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.0 0.2 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 0.2 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.1 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.4 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.1 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.0 0.3 GO:0003091 renal water homeostasis(GO:0003091)
0.0 0.0 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.0 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.1 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.0 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0019034 viral replication complex(GO:0019034)
0.3 0.8 GO:0031084 BLOC-2 complex(GO:0031084)
0.2 2.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.2 2.5 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.2 0.6 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.1 1.0 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 0.8 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.6 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.1 0.3 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 0.3 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.1 0.4 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.7 GO:0016589 NURF complex(GO:0016589)
0.1 0.5 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 0.6 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.6 GO:0042587 glycogen granule(GO:0042587)
0.1 1.4 GO:0010369 chromocenter(GO:0010369)
0.1 0.7 GO:0032039 integrator complex(GO:0032039)
0.0 0.2 GO:0033263 CORVET complex(GO:0033263)
0.0 0.5 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.2 GO:0071817 MMXD complex(GO:0071817)
0.0 0.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.4 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.3 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 2.9 GO:0016235 aggresome(GO:0016235)
0.0 0.3 GO:0044294 dendritic growth cone(GO:0044294)
0.0 1.9 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.2 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.4 GO:0097433 dense body(GO:0097433)
0.0 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.2 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.3 GO:0000801 central element(GO:0000801)
0.0 2.6 GO:0002102 podosome(GO:0002102)
0.0 0.5 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 0.3 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.2 GO:0097422 tubular endosome(GO:0097422)
0.0 0.3 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.1 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 0.1 GO:0005960 glycine cleavage complex(GO:0005960)
0.0 0.4 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.6 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.7 GO:0031143 pseudopodium(GO:0031143)
0.0 0.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.3 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.4 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.2 GO:0030897 HOPS complex(GO:0030897)
0.0 0.2 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.1 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.1 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 0.2 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 3.9 GO:0043296 apical junction complex(GO:0043296)
0.0 0.3 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.0 0.3 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.3 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.1 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.2 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.1 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.0 GO:0035841 new growing cell tip(GO:0035841)
0.0 0.3 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.2 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.5 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.3 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 1.9 GO:0030175 filopodium(GO:0030175)
0.0 0.3 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.3 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 0.1 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.1 GO:0035253 ciliary rootlet(GO:0035253)
0.0 1.6 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0005642 annulate lamellae(GO:0005642)
0.0 1.8 GO:0001650 fibrillar center(GO:0001650)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.4 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.5 1.5 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.4 2.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.2 1.4 GO:0034046 poly(G) binding(GO:0034046)
0.2 0.6 GO:0070361 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.2 0.5 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.2 0.5 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.2 0.6 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.1 0.4 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.1 1.2 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.1 3.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 0.4 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 2.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.4 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.1 0.6 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.1 0.6 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 0.6 GO:1901474 azole transmembrane transporter activity(GO:1901474)
0.1 0.5 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.1 0.3 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 0.5 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 0.4 GO:0004348 glucosylceramidase activity(GO:0004348)
0.1 0.2 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 1.0 GO:0019826 oxygen sensor activity(GO:0019826)
0.1 0.9 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 3.1 GO:0005109 frizzled binding(GO:0005109)
0.1 0.6 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.1 0.2 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.1 0.6 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 0.8 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.3 GO:0005119 smoothened binding(GO:0005119)
0.1 0.4 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.3 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.2 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.0 0.6 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.2 GO:0035501 MH1 domain binding(GO:0035501)
0.0 0.1 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.1 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
0.0 0.1 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.0 0.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.1 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.0 0.4 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.8 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.4 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.3 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 0.3 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.0 1.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.3 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.4 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.6 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.2 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.3 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.2 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.0 0.3 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.7 GO:0005351 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0 0.1 GO:0070538 oleic acid binding(GO:0070538)
0.0 0.2 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.1 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.3 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.0 0.1 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.0 0.1 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0 1.1 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.1 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0031177 S-acetyltransferase activity(GO:0016418) phosphopantetheine binding(GO:0031177)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.4 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.7 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.2 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 1.3 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0003867 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.0 0.1 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.0 0.7 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.4 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.1 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.2 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.4 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.9 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.1 GO:0004802 transketolase activity(GO:0004802)
0.0 0.5 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 2.2 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 1.1 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.1 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.1 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.2 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.1 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 1.0 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.4 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.3 GO:0010181 FMN binding(GO:0010181)
0.0 0.1 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.5 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 1.9 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.1 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.1 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.2 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.4 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.3 GO:0000295 adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.0 0.6 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.9 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 1.0 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.1 GO:0070568 guanylyltransferase activity(GO:0070568)
0.0 0.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.1 GO:0015295 solute:proton symporter activity(GO:0015295)
0.0 0.3 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.0 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.0 0.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.4 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.4 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.0 0.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.0 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.0 0.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.0 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.3 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.2 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 0.5 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.4 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.0 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.0 0.7 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.0 0.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.0 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.0 GO:0004813 alanine-tRNA ligase activity(GO:0004813)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.1 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.8 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.4 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.9 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 2.1 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.9 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.0 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.3 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 1.7 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.4 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.3 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.2 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.5 ST GAQ PATHWAY G alpha q Pathway
0.0 0.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.0 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.9 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 1.1 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.3 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 1.0 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 2.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 1.0 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 0.9 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 1.1 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 1.2 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.5 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 2.4 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.6 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.0 0.9 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 1.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.4 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.2 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.2 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 0.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.8 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.5 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.8 REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.0 0.7 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.2 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.1 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.2 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.4 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.3 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.0 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.2 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.2 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.5 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 1.1 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.2 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.3 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules