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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for TGIF1

Z-value: 0.70

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Transcription factors associated with TGIF1

Gene Symbol Gene ID Gene Info
TGIF1
ENSG00000177426.16 TGFB induced factor homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TGIF1hg19_v2_chr18_+_3449330_3449411-0.291.6e-01Click!

Activity profile of TGIF1 motif

Sorted Z-values of TGIF1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_68165657 1.62 ENST00000243457.3
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr15_-_70994612 1.26 ENST00000558758.1
ENST00000379983.2
ENST00000560441.1
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr4_+_42399856 1.23 ENST00000319234.4
SHISA3
shisa family member 3
chr17_-_53809473 1.22 ENST00000575734.1
TMEM100
transmembrane protein 100
chr1_+_221051699 1.12 ENST00000366903.6
HLX
H2.0-like homeobox
chr2_+_33359687 1.03 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
LTBP1
latent transforming growth factor beta binding protein 1
chr9_-_132805430 1.02 ENST00000446176.2
ENST00000355681.3
ENST00000420781.1
FNBP1
formin binding protein 1
chr2_+_173686303 1.02 ENST00000397087.3
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr2_+_33359646 1.01 ENST00000390003.4
ENST00000418533.2
LTBP1
latent transforming growth factor beta binding protein 1
chr21_-_35987438 1.00 ENST00000313806.4
RCAN1
regulator of calcineurin 1
chr1_+_100111580 0.98 ENST00000605497.1
PALMD
palmdelphin
chr9_+_34652164 0.91 ENST00000441545.2
ENST00000553620.1
IL11RA
interleukin 11 receptor, alpha
chr15_+_57668695 0.89 ENST00000281282.5
CGNL1
cingulin-like 1
chr7_+_30951461 0.89 ENST00000311813.4
AQP1
aquaporin 1 (Colton blood group)
chr6_-_10415218 0.88 ENST00000466073.1
ENST00000498450.1
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr8_-_6420565 0.85 ENST00000338312.6
ANGPT2
angiopoietin 2
chr5_-_94620239 0.81 ENST00000515393.1
MCTP1
multiple C2 domains, transmembrane 1
chr8_-_6420777 0.81 ENST00000415216.1
ANGPT2
angiopoietin 2
chr8_-_6420930 0.80 ENST00000325203.5
ANGPT2
angiopoietin 2
chr8_-_6420759 0.77 ENST00000523120.1
ANGPT2
angiopoietin 2
chr9_-_16728161 0.72 ENST00000603713.1
ENST00000603313.1
BNC2
basonuclin 2
chr3_+_45067659 0.72 ENST00000296130.4
CLEC3B
C-type lectin domain family 3, member B
chr8_-_82395461 0.69 ENST00000256104.4
FABP4
fatty acid binding protein 4, adipocyte
chr3_+_63897605 0.67 ENST00000487717.1
ATXN7
ataxin 7
chr6_+_50061315 0.64 ENST00000415106.1
RP11-397G17.1
RP11-397G17.1
chr6_+_29274403 0.57 ENST00000377160.2
OR14J1
olfactory receptor, family 14, subfamily J, member 1
chr17_+_61571746 0.56 ENST00000579409.1
ACE
angiotensin I converting enzyme
chr12_-_25348007 0.52 ENST00000354189.5
ENST00000545133.1
ENST00000554347.1
ENST00000395987.3
ENST00000320267.9
ENST00000395990.2
ENST00000537577.1
CASC1
cancer susceptibility candidate 1
chr16_-_2205352 0.52 ENST00000563192.1
RP11-304L19.5
RP11-304L19.5
chr2_-_73460334 0.50 ENST00000258083.2
PRADC1
protease-associated domain containing 1
chr9_+_130860810 0.50 ENST00000433501.1
SLC25A25
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr21_+_46117087 0.49 ENST00000400365.3
KRTAP10-12
keratin associated protein 10-12
chr14_-_100842588 0.49 ENST00000556645.1
ENST00000556209.1
ENST00000556504.1
ENST00000556435.1
ENST00000554772.1
ENST00000553581.1
ENST00000553769.2
ENST00000554605.1
ENST00000557722.1
ENST00000553413.1
ENST00000553524.1
ENST00000358655.4
WARS
tryptophanyl-tRNA synthetase
chr14_+_63671105 0.48 ENST00000316754.3
RHOJ
ras homolog family member J
chr12_+_108908962 0.48 ENST00000552695.1
ENST00000552758.1
ENST00000361549.2
FICD
FIC domain containing
chr11_+_103907308 0.47 ENST00000302259.3
DDI1
DNA-damage inducible 1 homolog 1 (S. cerevisiae)
chr18_-_52989525 0.45 ENST00000457482.3
TCF4
transcription factor 4
chr18_-_52969844 0.44 ENST00000561831.3
TCF4
transcription factor 4
chr5_-_78281603 0.44 ENST00000264914.4
ARSB
arylsulfatase B
chr9_+_116207007 0.43 ENST00000374140.2
RGS3
regulator of G-protein signaling 3
chr3_-_18466026 0.43 ENST00000417717.2
SATB1
SATB homeobox 1
chr15_-_82338460 0.43 ENST00000558133.1
ENST00000329713.4
MEX3B
mex-3 RNA binding family member B
chr2_+_228678550 0.43 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr9_+_130860583 0.42 ENST00000373064.5
SLC25A25
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr2_+_24714729 0.42 ENST00000406961.1
ENST00000405141.1
NCOA1
nuclear receptor coactivator 1
chr12_-_39837192 0.42 ENST00000361961.3
ENST00000395670.3
KIF21A
kinesin family member 21A
chr4_-_114682936 0.42 ENST00000454265.2
ENST00000429180.1
ENST00000418639.2
ENST00000394526.2
ENST00000296402.5
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr4_-_114682597 0.42 ENST00000394524.3
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr6_+_25652501 0.41 ENST00000334979.6
SCGN
secretagogin, EF-hand calcium binding protein
chr17_-_76899275 0.41 ENST00000322630.2
ENST00000586713.1
DDC8
Protein DDC8 homolog
chr9_-_36276966 0.41 ENST00000543356.2
ENST00000396594.3
GNE
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr11_+_6411670 0.40 ENST00000530395.1
ENST00000527275.1
SMPD1
sphingomyelin phosphodiesterase 1, acid lysosomal
chr3_-_56809685 0.40 ENST00000413728.2
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr3_-_49823941 0.39 ENST00000321599.4
ENST00000395238.1
ENST00000468463.1
ENST00000460540.1
IP6K1
inositol hexakisphosphate kinase 1
chr7_-_94285472 0.38 ENST00000437425.2
ENST00000447873.1
ENST00000415788.2
SGCE
sarcoglycan, epsilon
chr11_+_6411636 0.38 ENST00000299397.3
ENST00000356761.2
ENST00000342245.4
SMPD1
sphingomyelin phosphodiesterase 1, acid lysosomal
chr17_+_4402133 0.37 ENST00000329078.3
SPNS2
spinster homolog 2 (Drosophila)
chr17_+_26369865 0.37 ENST00000582037.1
NLK
nemo-like kinase
chr9_-_16727978 0.37 ENST00000418777.1
ENST00000468187.2
BNC2
basonuclin 2
chr20_-_50418947 0.37 ENST00000371539.3
SALL4
spalt-like transcription factor 4
chr20_-_50418972 0.37 ENST00000395997.3
SALL4
spalt-like transcription factor 4
chr17_-_66951474 0.36 ENST00000269080.2
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr17_-_79869004 0.36 ENST00000573927.1
ENST00000331285.3
ENST00000572157.1
PCYT2
phosphate cytidylyltransferase 2, ethanolamine
chr3_+_38017264 0.35 ENST00000436654.1
CTDSPL
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr3_-_52719810 0.35 ENST00000424867.1
ENST00000394830.3
ENST00000431678.1
ENST00000450271.1
PBRM1
polybromo 1
chr11_+_120973375 0.35 ENST00000264037.2
TECTA
tectorin alpha
chr14_+_24867992 0.35 ENST00000382554.3
NYNRIN
NYN domain and retroviral integrase containing
chr9_+_134065506 0.35 ENST00000483497.2
NUP214
nucleoporin 214kDa
chr2_+_33661382 0.34 ENST00000402538.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr10_+_28822636 0.34 ENST00000442148.1
ENST00000448193.1
WAC
WW domain containing adaptor with coiled-coil
chr6_-_13487784 0.34 ENST00000379287.3
GFOD1
glucose-fructose oxidoreductase domain containing 1
chr5_+_125758813 0.34 ENST00000285689.3
ENST00000515200.1
GRAMD3
GRAM domain containing 3
chr7_-_94285402 0.34 ENST00000428696.2
ENST00000445866.2
SGCE
sarcoglycan, epsilon
chr11_-_73687997 0.34 ENST00000545212.1
UCP2
uncoupling protein 2 (mitochondrial, proton carrier)
chr17_+_26646175 0.34 ENST00000583381.1
ENST00000582113.1
ENST00000582384.1
TMEM97
transmembrane protein 97
chr10_+_86004802 0.33 ENST00000359452.4
ENST00000358110.5
ENST00000372092.3
RGR
retinal G protein coupled receptor
chr14_+_70078303 0.33 ENST00000342745.4
KIAA0247
KIAA0247
chr17_-_46623441 0.33 ENST00000330070.4
HOXB2
homeobox B2
chr17_-_27418537 0.33 ENST00000408971.2
TIAF1
TGFB1-induced anti-apoptotic factor 1
chr15_-_37392086 0.33 ENST00000561208.1
MEIS2
Meis homeobox 2
chr7_-_94285511 0.33 ENST00000265735.7
SGCE
sarcoglycan, epsilon
chr1_+_225600404 0.33 ENST00000366845.2
AC092811.1
AC092811.1
chr14_-_105635090 0.32 ENST00000331782.3
ENST00000347004.2
JAG2
jagged 2
chr19_-_10946949 0.32 ENST00000214869.2
ENST00000591695.1
TMED1
transmembrane emp24 protein transport domain containing 1
chr2_+_239756671 0.32 ENST00000448943.2
TWIST2
twist family bHLH transcription factor 2
chr2_+_97202480 0.32 ENST00000357485.3
ARID5A
AT rich interactive domain 5A (MRF1-like)
chr22_-_50219548 0.32 ENST00000404034.1
BRD1
bromodomain containing 1
chr2_-_36779411 0.32 ENST00000406220.1
AC007401.2
Uncharacterized protein
chr11_-_101000445 0.31 ENST00000534013.1
PGR
progesterone receptor
chr1_-_33168336 0.31 ENST00000373484.3
SYNC
syncoilin, intermediate filament protein
chr22_-_50523760 0.31 ENST00000395876.2
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr6_-_84418841 0.31 ENST00000369694.2
ENST00000195649.6
SNAP91
synaptosomal-associated protein, 91kDa
chr16_-_30582888 0.31 ENST00000563707.1
ENST00000567855.1
ZNF688
zinc finger protein 688
chr22_-_50524298 0.30 ENST00000311597.5
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr1_+_66999268 0.30 ENST00000371039.1
ENST00000424320.1
SGIP1
SH3-domain GRB2-like (endophilin) interacting protein 1
chr6_-_84418860 0.30 ENST00000521743.1
SNAP91
synaptosomal-associated protein, 91kDa
chr6_+_138188551 0.30 ENST00000237289.4
ENST00000433680.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr1_+_152943122 0.30 ENST00000328051.2
SPRR4
small proline-rich protein 4
chr19_+_49375649 0.30 ENST00000200453.5
PPP1R15A
protein phosphatase 1, regulatory subunit 15A
chr2_+_97203082 0.30 ENST00000454558.2
ARID5A
AT rich interactive domain 5A (MRF1-like)
chr21_-_34185944 0.29 ENST00000479548.1
C21orf62
chromosome 21 open reading frame 62
chr5_+_125758865 0.29 ENST00000542322.1
ENST00000544396.1
GRAMD3
GRAM domain containing 3
chr18_-_55253989 0.29 ENST00000262093.5
FECH
ferrochelatase
chr6_-_33714667 0.29 ENST00000293756.4
IP6K3
inositol hexakisphosphate kinase 3
chr11_-_128457446 0.28 ENST00000392668.4
ETS1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
chrX_+_110187513 0.28 ENST00000446737.1
ENST00000425146.1
PAK3
p21 protein (Cdc42/Rac)-activated kinase 3
chr17_-_72542278 0.27 ENST00000330793.1
CD300C
CD300c molecule
chr12_-_46121554 0.27 ENST00000609803.1
LINC00938
long intergenic non-protein coding RNA 938
chr6_-_33714752 0.27 ENST00000451316.1
IP6K3
inositol hexakisphosphate kinase 3
chr2_+_136343820 0.26 ENST00000410054.1
R3HDM1
R3H domain containing 1
chr12_+_15475331 0.26 ENST00000281171.4
PTPRO
protein tyrosine phosphatase, receptor type, O
chr17_-_79869077 0.25 ENST00000570391.1
PCYT2
phosphate cytidylyltransferase 2, ethanolamine
chr16_-_67217844 0.25 ENST00000563902.1
ENST00000561621.1
ENST00000290881.7
KIAA0895L
KIAA0895-like
chr1_+_2036149 0.24 ENST00000482686.1
ENST00000400920.1
ENST00000486681.1
PRKCZ
protein kinase C, zeta
chr8_-_29120580 0.24 ENST00000524189.1
KIF13B
kinesin family member 13B
chr2_-_235405168 0.24 ENST00000339728.3
ARL4C
ADP-ribosylation factor-like 4C
chr2_-_152589670 0.24 ENST00000604864.1
ENST00000603639.1
NEB
nebulin
chr12_-_63328817 0.24 ENST00000228705.6
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr10_-_124768300 0.24 ENST00000368886.5
IKZF5
IKAROS family zinc finger 5 (Pegasus)
chr8_+_22446763 0.24 ENST00000450780.2
ENST00000430850.2
ENST00000447849.1
AC037459.4
Uncharacterized protein
chr16_-_70557430 0.23 ENST00000393612.4
ENST00000564653.1
ENST00000323786.5
COG4
component of oligomeric golgi complex 4
chr11_+_842928 0.23 ENST00000397408.1
TSPAN4
tetraspanin 4
chr2_+_90458201 0.23 ENST00000603238.1
CH17-132F21.1
Uncharacterized protein
chr8_-_93029520 0.23 ENST00000521553.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr15_-_55562582 0.23 ENST00000396307.2
RAB27A
RAB27A, member RAS oncogene family
chr10_+_99349450 0.22 ENST00000370640.3
C10orf62
chromosome 10 open reading frame 62
chr6_+_33378738 0.22 ENST00000374512.3
ENST00000374516.3
PHF1
PHD finger protein 1
chrX_-_71792477 0.22 ENST00000421523.1
ENST00000415409.1
ENST00000373559.4
ENST00000373556.3
ENST00000373560.2
ENST00000373583.1
ENST00000429103.2
ENST00000373571.1
ENST00000373554.1
HDAC8
histone deacetylase 8
chr9_+_2159850 0.22 ENST00000416751.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr6_+_127439749 0.22 ENST00000356698.4
RSPO3
R-spondin 3
chr20_-_50159198 0.22 ENST00000371564.3
ENST00000396009.3
ENST00000610033.1
NFATC2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr15_+_97326659 0.22 ENST00000558553.1
SPATA8
spermatogenesis associated 8
chr7_+_95401851 0.21 ENST00000447467.2
DYNC1I1
dynein, cytoplasmic 1, intermediate chain 1
chr4_+_128886532 0.21 ENST00000444616.1
ENST00000388795.5
C4orf29
chromosome 4 open reading frame 29
chr10_-_48438974 0.21 ENST00000224605.2
GDF10
growth differentiation factor 10
chr20_-_50419055 0.21 ENST00000217086.4
SALL4
spalt-like transcription factor 4
chr9_-_100459639 0.21 ENST00000375128.4
XPA
xeroderma pigmentosum, complementation group A
chr3_-_71353892 0.21 ENST00000484350.1
FOXP1
forkhead box P1
chr20_-_5591626 0.20 ENST00000379019.4
GPCPD1
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr11_-_78128811 0.20 ENST00000530915.1
ENST00000361507.4
GAB2
GRB2-associated binding protein 2
chr17_-_72358001 0.20 ENST00000375366.3
BTBD17
BTB (POZ) domain containing 17
chrX_+_70338552 0.20 ENST00000374080.3
ENST00000429213.1
MED12
mediator complex subunit 12
chr19_-_51527467 0.20 ENST00000593681.1
KLK11
kallikrein-related peptidase 11
chr7_-_148580563 0.20 ENST00000476773.1
EZH2
enhancer of zeste homolog 2 (Drosophila)
chr19_-_20150252 0.20 ENST00000595736.1
ENST00000593468.1
ENST00000596019.1
ZNF682
zinc finger protein 682
chr5_-_44388899 0.19 ENST00000264664.4
FGF10
fibroblast growth factor 10
chr12_-_49318715 0.19 ENST00000444214.2
FKBP11
FK506 binding protein 11, 19 kDa
chr11_+_842808 0.19 ENST00000397397.2
ENST00000397411.2
ENST00000397396.1
TSPAN4
tetraspanin 4
chr20_+_35201993 0.19 ENST00000373872.4
TGIF2
TGFB-induced factor homeobox 2
chr14_+_24458093 0.19 ENST00000558753.1
ENST00000537912.1
DHRS4L2
dehydrogenase/reductase (SDR family) member 4 like 2
chr20_+_35201857 0.19 ENST00000373874.2
TGIF2
TGFB-induced factor homeobox 2
chr11_-_41481135 0.19 ENST00000528697.1
ENST00000530763.1
LRRC4C
leucine rich repeat containing 4C
chr1_+_110577229 0.19 ENST00000369795.3
ENST00000369794.2
STRIP1
striatin interacting protein 1
chr10_-_11574274 0.19 ENST00000277575.5
USP6NL
USP6 N-terminal like
chr7_+_94285637 0.19 ENST00000482108.1
ENST00000488574.1
PEG10
paternally expressed 10
chr1_-_150669500 0.18 ENST00000271732.3
GOLPH3L
golgi phosphoprotein 3-like
chr11_-_64901900 0.18 ENST00000526060.1
ENST00000307289.6
ENST00000528487.1
SYVN1
synovial apoptosis inhibitor 1, synoviolin
chr7_-_80141328 0.18 ENST00000398291.3
GNAT3
guanine nucleotide binding protein, alpha transducing 3
chr11_-_842509 0.18 ENST00000322028.4
POLR2L
polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
chr2_-_201729284 0.17 ENST00000434813.2
CLK1
CDC-like kinase 1
chr16_+_69458428 0.17 ENST00000512062.1
ENST00000307892.8
CYB5B
cytochrome b5 type B (outer mitochondrial membrane)
chr4_-_114682364 0.17 ENST00000511664.1
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr15_-_55562479 0.17 ENST00000564609.1
RAB27A
RAB27A, member RAS oncogene family
chr6_-_31651817 0.17 ENST00000375863.3
ENST00000375860.2
LY6G5C
lymphocyte antigen 6 complex, locus G5C
chr1_-_231114542 0.17 ENST00000522821.1
ENST00000366661.4
ENST00000366662.4
ENST00000414259.1
ENST00000522399.1
TTC13
tetratricopeptide repeat domain 13
chr15_+_97326619 0.17 ENST00000328504.3
SPATA8
spermatogenesis associated 8
chr5_+_143191726 0.17 ENST00000289448.2
HMHB1
histocompatibility (minor) HB-1
chr9_-_115653176 0.17 ENST00000374228.4
SLC46A2
solute carrier family 46, member 2
chr20_+_22034809 0.17 ENST00000449427.1
RP11-125P18.1
RP11-125P18.1
chr4_+_52709229 0.16 ENST00000334635.5
ENST00000381441.3
ENST00000381437.4
DCUN1D4
DCN1, defective in cullin neddylation 1, domain containing 4
chrX_-_99986494 0.16 ENST00000372989.1
ENST00000455616.1
ENST00000454200.2
ENST00000276141.6
SYTL4
synaptotagmin-like 4
chr19_-_55686399 0.16 ENST00000587067.1
SYT5
synaptotagmin V
chr11_-_123756334 0.16 ENST00000528595.1
ENST00000375026.2
TMEM225
transmembrane protein 225
chr7_+_120591170 0.16 ENST00000431467.1
ING3
inhibitor of growth family, member 3
chr8_-_141931287 0.16 ENST00000517887.1
PTK2
protein tyrosine kinase 2
chr11_-_6426635 0.16 ENST00000608645.1
ENST00000608394.1
ENST00000529519.1
APBB1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr6_+_32146131 0.16 ENST00000375094.3
RNF5
ring finger protein 5, E3 ubiquitin protein ligase
chr4_-_16228083 0.16 ENST00000399920.3
TAPT1
transmembrane anterior posterior transformation 1
chr11_-_64901978 0.16 ENST00000294256.8
ENST00000377190.3
SYVN1
synovial apoptosis inhibitor 1, synoviolin
chr19_-_20150014 0.16 ENST00000358523.5
ENST00000397162.1
ENST00000601100.1
ZNF682
zinc finger protein 682
chr1_-_150978953 0.15 ENST00000493834.2
FAM63A
family with sequence similarity 63, member A
chr22_-_37882395 0.15 ENST00000416983.3
ENST00000424765.2
ENST00000356998.3
MFNG
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr2_-_3595547 0.15 ENST00000438485.1
RP13-512J5.1
Uncharacterized protein
chr8_-_67090825 0.15 ENST00000276571.3
CRH
corticotropin releasing hormone
chr5_+_72143988 0.15 ENST00000506351.2
TNPO1
transportin 1
chr5_+_140868717 0.15 ENST00000252087.1
PCDHGC5
protocadherin gamma subfamily C, 5
chrX_+_118425471 0.15 ENST00000428222.1
RP5-1139I1.1
RP5-1139I1.1
chr19_-_44143939 0.15 ENST00000222374.2
CADM4
cell adhesion molecule 4
chr17_-_3417062 0.15 ENST00000570318.1
ENST00000541913.1
SPATA22
spermatogenesis associated 22
chr19_-_20150301 0.15 ENST00000397165.2
ZNF682
zinc finger protein 682
chr19_-_48547294 0.15 ENST00000293255.2
CABP5
calcium binding protein 5
chr14_+_31494672 0.14 ENST00000542754.2
ENST00000313566.6
AP4S1
adaptor-related protein complex 4, sigma 1 subunit
chr22_-_30960876 0.14 ENST00000401975.1
ENST00000428682.1
ENST00000423299.1
GAL3ST1
galactose-3-O-sulfotransferase 1
chr12_+_104458235 0.14 ENST00000229330.4
HCFC2
host cell factor C2
chr16_+_50775948 0.14 ENST00000569681.1
ENST00000569418.1
ENST00000540145.1
CYLD
cylindromatosis (turban tumor syndrome)
chr10_+_94608245 0.14 ENST00000443748.2
ENST00000260762.6
EXOC6
exocyst complex component 6
chr1_-_151119087 0.14 ENST00000341697.3
ENST00000368914.3
SEMA6C
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
chr4_-_2420357 0.14 ENST00000511071.1
ENST00000509171.1
ENST00000290974.2
ZFYVE28
zinc finger, FYVE domain containing 28
chr6_+_41021027 0.14 ENST00000244669.2
APOBEC2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
chr2_-_201729393 0.14 ENST00000321356.4
CLK1
CDC-like kinase 1

Network of associatons between targets according to the STRING database.

First level regulatory network of TGIF1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.2 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.4 1.6 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.3 0.9 GO:0072019 carbon dioxide transmembrane transport(GO:0035378) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
0.2 0.9 GO:0003409 optic cup structural organization(GO:0003409)
0.2 0.5 GO:0061582 intestinal epithelial cell migration(GO:0061582)
0.2 1.6 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 0.4 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.1 0.4 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.1 0.6 GO:1903597 negative regulation of gap junction assembly(GO:1903597)
0.1 1.1 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 1.2 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.1 0.3 GO:1990108 protein linear deubiquitination(GO:1990108)
0.1 0.3 GO:0021569 rhombomere 3 development(GO:0021569)
0.1 0.8 GO:0023021 termination of signal transduction(GO:0023021)
0.1 0.7 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.1 0.4 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.1 0.3 GO:0071947 B-1 B cell homeostasis(GO:0001922) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947) negative regulation of osteoclast proliferation(GO:0090291)
0.1 0.3 GO:1902310 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.1 0.5 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 0.3 GO:0070541 response to platinum ion(GO:0070541)
0.1 0.3 GO:0009912 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.1 0.3 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.1 0.2 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.1 0.2 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 0.4 GO:0048073 regulation of eye pigmentation(GO:0048073)
0.1 0.2 GO:0071922 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.1 1.0 GO:1901725 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909) regulation of histone deacetylase activity(GO:1901725)
0.1 0.2 GO:2000854 positive regulation of corticosterone secretion(GO:2000854)
0.1 0.4 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 0.2 GO:1904772 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.1 0.2 GO:0009946 proximal/distal axis specification(GO:0009946) male genitalia morphogenesis(GO:0048808) bronchiole development(GO:0060435) positive regulation of white fat cell proliferation(GO:0070352) male anatomical structure morphogenesis(GO:0090598)
0.1 0.9 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.2 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.1 0.7 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.2 GO:0050758 thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758)
0.1 0.9 GO:0015866 ADP transport(GO:0015866)
0.0 0.2 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0 0.2 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.1 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.0 0.2 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.2 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.0 0.2 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.0 0.2 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.2 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.1 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.0 0.7 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.3 GO:0030578 PML body organization(GO:0030578)
0.0 0.7 GO:0072584 caveolin-mediated endocytosis(GO:0072584)
0.0 0.3 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.1 GO:0046125 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) beta-alanine metabolic process(GO:0019482) thymine metabolic process(GO:0019859) uracil metabolic process(GO:0019860) thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0 0.2 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.0 0.1 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.5 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.1 GO:0016095 polyprenol catabolic process(GO:0016095)
0.0 0.2 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0 0.4 GO:0042908 xenobiotic transport(GO:0042908)
0.0 1.1 GO:0003416 endochondral bone growth(GO:0003416)
0.0 0.4 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.4 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.3 GO:0015074 DNA integration(GO:0015074)
0.0 0.2 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 0.1 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.2 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.3 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.1 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.0 0.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.3 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.6 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:1902995 regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995) positive regulation of receptor catabolic process(GO:2000646)
0.0 0.2 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.6 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.1 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 0.1 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.0 0.4 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.0 0.1 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.2 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.1 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.4 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.0 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
0.0 0.1 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.0 0.1 GO:0042377 menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377)
0.0 0.2 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.1 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.0 0.1 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.1 GO:0048368 lateral mesoderm development(GO:0048368)
0.0 0.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.6 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.4 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.2 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.3 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.0 0.5 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.2 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.1 GO:0033623 positive regulation of platelet activation(GO:0010572) regulation of integrin activation(GO:0033623)
0.0 0.1 GO:1990441 negative regulation of PERK-mediated unfolded protein response(GO:1903898) negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990441)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0020005 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.1 0.7 GO:0001652 granular component(GO:0001652)
0.1 0.3 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.1 0.9 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.3 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 1.6 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.2 GO:0071020 post-spliceosomal complex(GO:0071020)
0.0 0.2 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.2 GO:1990812 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.0 1.6 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.7 GO:0042599 lamellar body(GO:0042599)
0.0 0.1 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.4 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.3 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0045179 axon hillock(GO:0043203) apical cortex(GO:0045179)
0.0 0.1 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.1 GO:0043196 varicosity(GO:0043196)
0.0 1.0 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.2 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.2 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.5 GO:0090544 BAF-type complex(GO:0090544)
0.0 1.4 GO:0000792 heterochromatin(GO:0000792)
0.0 0.3 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 1.1 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.0 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 1.0 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.1 GO:0050436 microfibril binding(GO:0050436)
0.3 0.9 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.2 0.9 GO:0052839 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.2 0.5 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.2 1.0 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.4 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.1 0.6 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.1 0.5 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 0.6 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.1 1.6 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 1.1 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.2 GO:0000384 first spliceosomal transesterification activity(GO:0000384)
0.1 0.4 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.1 0.9 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.2 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.2 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.8 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.9 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.3 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.3 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.7 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.4 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.0 0.1 GO:0042806 fucose binding(GO:0042806)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 2.9 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 1.0 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.1 GO:0047023 androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718)
0.0 0.6 GO:0005549 odorant binding(GO:0005549)
0.0 0.2 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.1 GO:0004608 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.1 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.2 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.4 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.5 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.1 GO:0061714 folic acid receptor activity(GO:0061714)
0.0 0.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.1 GO:0003826 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.0 0.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.0 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.1 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.2 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.0 GO:0031768 ghrelin receptor binding(GO:0031768)
0.0 0.2 GO:0048156 tau protein binding(GO:0048156)
0.0 0.4 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.3 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)
0.0 0.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.1 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.0 0.2 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.5 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.1 GO:0033265 choline binding(GO:0033265)
0.0 0.6 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.2 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.3 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.6 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 3.6 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.3 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.5 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.2 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.3 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.5 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.3 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.8 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 1.6 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 0.8 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 1.1 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 1.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.5 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.3 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.3 REACTOME OPSINS Genes involved in Opsins
0.0 0.9 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 1.2 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.0 1.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.6 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.9 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation