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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for TP53

Z-value: 0.54

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Transcription factors associated with TP53

Gene Symbol Gene ID Gene Info
TP53
ENSG00000141510.11 tumor protein p53

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TP53hg19_v2_chr17_-_7590745_75908560.672.3e-04Click!

Activity profile of TP53 motif

Sorted Z-values of TP53 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_57406368 2.03 ENST00000006053.6
ENST00000563383.1
CX3CL1
chemokine (C-X3-C motif) ligand 1
chr5_-_131826457 1.78 ENST00000437654.1
ENST00000245414.4
IRF1
interferon regulatory factor 1
chr8_-_22926526 1.18 ENST00000347739.3
ENST00000542226.1
TNFRSF10B
tumor necrosis factor receptor superfamily, member 10b
chr16_+_57653989 1.06 ENST00000567835.1
ENST00000569372.1
ENST00000563548.1
ENST00000562003.1
GPR56
G protein-coupled receptor 56
chr16_+_57653854 1.05 ENST00000568908.1
ENST00000568909.1
ENST00000566778.1
ENST00000561988.1
GPR56
G protein-coupled receptor 56
chr4_+_103422471 1.05 ENST00000226574.4
ENST00000394820.4
NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr18_+_57567180 1.04 ENST00000316660.6
ENST00000269518.9
PMAIP1
phorbol-12-myristate-13-acetate-induced protein 1
chr10_+_90750493 0.96 ENST00000357339.2
ENST00000355279.2
FAS
Fas cell surface death receptor
chr6_-_101329157 0.92 ENST00000369143.2
ASCC3
activating signal cointegrator 1 complex subunit 3
chr4_-_10117949 0.89 ENST00000508079.1
WDR1
WD repeat domain 1
chr6_-_30709980 0.86 ENST00000416018.1
ENST00000445853.1
ENST00000413165.1
ENST00000418160.1
FLOT1
flotillin 1
chr1_-_201438282 0.80 ENST00000367311.3
ENST00000367309.1
PHLDA3
pleckstrin homology-like domain, family A, member 3
chr5_-_95297534 0.79 ENST00000513343.1
ENST00000431061.2
ELL2
elongation factor, RNA polymerase II, 2
chr1_-_209825674 0.78 ENST00000367030.3
ENST00000356082.4
LAMB3
laminin, beta 3
chr17_+_74372662 0.78 ENST00000591651.1
ENST00000545180.1
SPHK1
sphingosine kinase 1
chr19_-_47735918 0.77 ENST00000449228.1
ENST00000300880.7
ENST00000341983.4
BBC3
BCL2 binding component 3
chr10_-_90751038 0.77 ENST00000458159.1
ENST00000415557.1
ENST00000458208.1
ACTA2
actin, alpha 2, smooth muscle, aorta
chr8_-_22926623 0.75 ENST00000276431.4
TNFRSF10B
tumor necrosis factor receptor superfamily, member 10b
chr12_-_6451186 0.72 ENST00000540022.1
ENST00000536194.1
TNFRSF1A
tumor necrosis factor receptor superfamily, member 1A
chr17_+_80332153 0.71 ENST00000313135.2
UTS2R
urotensin 2 receptor
chr6_-_138428613 0.70 ENST00000421351.3
PERP
PERP, TP53 apoptosis effector
chr6_+_4776580 0.69 ENST00000397588.3
CDYL
chromodomain protein, Y-like
chr22_+_21133469 0.67 ENST00000406799.1
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr12_+_22778291 0.65 ENST00000545979.1
ETNK1
ethanolamine kinase 1
chr15_+_89164520 0.65 ENST00000332810.3
AEN
apoptosis enhancing nuclease
chr1_-_150738261 0.62 ENST00000448301.2
ENST00000368985.3
CTSS
cathepsin S
chr20_+_4129496 0.60 ENST00000346595.2
SMOX
spermine oxidase
chr11_-_3078838 0.58 ENST00000397111.5
CARS
cysteinyl-tRNA synthetase
chr10_+_134000404 0.58 ENST00000338492.4
ENST00000368629.1
DPYSL4
dihydropyrimidinase-like 4
chr11_-_3078616 0.57 ENST00000401769.3
ENST00000278224.9
ENST00000397114.3
ENST00000380525.4
CARS
cysteinyl-tRNA synthetase
chr11_-_108464465 0.55 ENST00000525344.1
EXPH5
exophilin 5
chr19_+_49458107 0.53 ENST00000539787.1
ENST00000345358.7
ENST00000391871.3
ENST00000415969.2
ENST00000354470.3
ENST00000506183.1
ENST00000293288.8
BAX
BCL2-associated X protein
chrX_+_152086373 0.49 ENST00000318529.8
ZNF185
zinc finger protein 185 (LIM domain)
chr13_-_102068706 0.49 ENST00000251127.6
NALCN
sodium leak channel, non-selective
chr20_+_4129426 0.49 ENST00000339123.6
ENST00000305958.4
ENST00000278795.3
SMOX
spermine oxidase
chr12_-_6451235 0.49 ENST00000440083.2
ENST00000162749.2
TNFRSF1A
tumor necrosis factor receptor superfamily, member 1A
chr7_+_100770328 0.47 ENST00000223095.4
ENST00000445463.2
SERPINE1
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr11_+_61717279 0.47 ENST00000378043.4
BEST1
bestrophin 1
chr22_-_18257178 0.46 ENST00000342111.5
BID
BH3 interacting domain death agonist
chr1_+_156052354 0.46 ENST00000368301.2
LMNA
lamin A/C
chr10_+_124134201 0.46 ENST00000368990.3
ENST00000368988.1
ENST00000368989.2
ENST00000463663.2
PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr11_+_61717336 0.46 ENST00000378042.3
BEST1
bestrophin 1
chr6_-_101329191 0.44 ENST00000324723.6
ENST00000369162.2
ENST00000522650.1
ASCC3
activating signal cointegrator 1 complex subunit 3
chr19_+_489140 0.44 ENST00000587541.1
MADCAM1
mucosal vascular addressin cell adhesion molecule 1
chr17_+_76210267 0.44 ENST00000301633.4
ENST00000350051.3
ENST00000374948.2
ENST00000590449.1
BIRC5
baculoviral IAP repeat containing 5
chr9_+_139847347 0.43 ENST00000371632.3
LCN12
lipocalin 12
chr1_+_13910757 0.43 ENST00000376061.4
ENST00000513143.1
PDPN
podoplanin
chr19_-_2456922 0.42 ENST00000582871.1
ENST00000325327.3
LMNB2
lamin B2
chr13_+_38923959 0.39 ENST00000379649.1
ENST00000239878.4
ENST00000437952.1
ENST00000379641.1
UFM1
ubiquitin-fold modifier 1
chr11_-_59383617 0.39 ENST00000263847.1
OSBP
oxysterol binding protein
chr15_-_72767490 0.38 ENST00000565181.1
RP11-1007O24.3
RP11-1007O24.3
chr12_+_69202795 0.38 ENST00000539479.1
ENST00000393415.3
ENST00000523991.1
ENST00000543323.1
ENST00000393416.2
MDM2
MDM2 oncogene, E3 ubiquitin protein ligase
chr9_+_80912059 0.37 ENST00000347159.2
ENST00000376588.3
PSAT1
phosphoserine aminotransferase 1
chr2_-_47168850 0.37 ENST00000409207.1
MCFD2
multiple coagulation factor deficiency 2
chr4_-_10118469 0.37 ENST00000499869.2
WDR1
WD repeat domain 1
chr4_-_10118348 0.37 ENST00000502702.1
WDR1
WD repeat domain 1
chr22_-_18257249 0.36 ENST00000399765.1
ENST00000399767.1
ENST00000399774.3
BID
BH3 interacting domain death agonist
chr20_-_1373682 0.36 ENST00000381724.3
FKBP1A
FK506 binding protein 1A, 12kDa
chr11_+_33279850 0.35 ENST00000531504.1
ENST00000456517.1
HIPK3
homeodomain interacting protein kinase 3
chr6_+_116692102 0.35 ENST00000359564.2
DSE
dermatan sulfate epimerase
chr17_+_76210367 0.35 ENST00000592734.1
ENST00000587746.1
BIRC5
baculoviral IAP repeat containing 5
chr1_+_54519242 0.35 ENST00000234827.1
TCEANC2
transcription elongation factor A (SII) N-terminal and central domain containing 2
chr1_+_114447763 0.34 ENST00000369563.3
DCLRE1B
DNA cross-link repair 1B
chr11_+_33278811 0.34 ENST00000303296.4
ENST00000379016.3
HIPK3
homeodomain interacting protein kinase 3
chr19_-_42746714 0.34 ENST00000222330.3
GSK3A
glycogen synthase kinase 3 alpha
chr8_+_22960426 0.33 ENST00000540813.1
TNFRSF10C
tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
chr20_-_1373606 0.33 ENST00000381715.1
ENST00000439640.2
ENST00000381719.3
FKBP1A
FK506 binding protein 1A, 12kDa
chr14_-_50999190 0.33 ENST00000557390.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr11_-_65626753 0.33 ENST00000526975.1
ENST00000531413.1
CFL1
cofilin 1 (non-muscle)
chr7_-_72439997 0.32 ENST00000285805.3
TRIM74
tripartite motif containing 74
chr22_-_39239987 0.32 ENST00000333039.2
NPTXR
neuronal pentraxin receptor
chr4_-_10118573 0.30 ENST00000382452.2
ENST00000382451.2
WDR1
WD repeat domain 1
chr1_+_11796177 0.30 ENST00000400895.2
ENST00000376629.4
ENST00000376627.2
ENST00000314340.5
ENST00000452018.2
ENST00000510878.1
AGTRAP
angiotensin II receptor-associated protein
chr16_-_67997947 0.30 ENST00000537830.2
SLC12A4
solute carrier family 12 (potassium/chloride transporter), member 4
chr20_-_45035223 0.30 ENST00000450812.1
ENST00000290246.6
ENST00000439931.2
ENST00000396391.1
ELMO2
engulfment and cell motility 2
chr9_-_135996537 0.30 ENST00000372050.3
ENST00000372047.3
RALGDS
ral guanine nucleotide dissociation stimulator
chr8_+_120428546 0.30 ENST00000259526.3
NOV
nephroblastoma overexpressed
chr1_-_2458026 0.30 ENST00000435556.3
ENST00000378466.3
PANK4
pantothenate kinase 4
chr15_-_89456630 0.30 ENST00000268150.8
MFGE8
milk fat globule-EGF factor 8 protein
chr2_+_47168313 0.30 ENST00000319190.5
ENST00000394850.2
ENST00000536057.1
TTC7A
tetratricopeptide repeat domain 7A
chr20_-_45035198 0.29 ENST00000372176.1
ELMO2
engulfment and cell motility 2
chr8_-_12612962 0.28 ENST00000398246.3
LONRF1
LON peptidase N-terminal domain and ring finger 1
chr22_+_38302285 0.28 ENST00000215957.6
MICALL1
MICAL-like 1
chr16_-_68000717 0.28 ENST00000541864.2
SLC12A4
solute carrier family 12 (potassium/chloride transporter), member 4
chr7_-_100493482 0.27 ENST00000411582.1
ENST00000419336.2
ENST00000241069.5
ENST00000302913.4
ACHE
acetylcholinesterase (Yt blood group)
chr22_-_38484922 0.27 ENST00000428572.1
BAIAP2L2
BAI1-associated protein 2-like 2
chr1_-_160832642 0.27 ENST00000368034.4
CD244
CD244 molecule, natural killer cell receptor 2B4
chr12_+_69202975 0.27 ENST00000544561.1
ENST00000393410.1
ENST00000299252.4
ENST00000360430.2
ENST00000517852.1
ENST00000545204.1
ENST00000393413.3
ENST00000350057.5
ENST00000348801.2
ENST00000478070.1
MDM2
MDM2 oncogene, E3 ubiquitin protein ligase
chr3_-_113464906 0.27 ENST00000477813.1
NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr4_-_187644930 0.26 ENST00000441802.2
FAT1
FAT atypical cadherin 1
chr13_-_50367057 0.26 ENST00000261667.3
KPNA3
karyopherin alpha 3 (importin alpha 4)
chr20_-_1373726 0.26 ENST00000400137.4
FKBP1A
FK506 binding protein 1A, 12kDa
chr19_+_35862192 0.25 ENST00000597214.1
GPR42
G protein-coupled receptor 42 (gene/pseudogene)
chr7_+_129074266 0.25 ENST00000249344.2
ENST00000435494.2
STRIP2
striatin interacting protein 2
chr7_-_100493744 0.25 ENST00000428317.1
ENST00000441605.1
ACHE
acetylcholinesterase (Yt blood group)
chr1_+_13910479 0.24 ENST00000509009.1
PDPN
podoplanin
chr8_-_23082580 0.24 ENST00000221132.3
TNFRSF10A
tumor necrosis factor receptor superfamily, member 10a
chr8_-_10588010 0.24 ENST00000304501.1
SOX7
SRY (sex determining region Y)-box 7
chr9_+_130186653 0.24 ENST00000342483.5
ENST00000543471.1
ZNF79
zinc finger protein 79
chr22_+_29279552 0.24 ENST00000544604.2
ZNRF3
zinc and ring finger 3
chr19_+_35861831 0.24 ENST00000454971.1
GPR42
G protein-coupled receptor 42 (gene/pseudogene)
chr12_-_53207842 0.24 ENST00000458244.2
KRT4
keratin 4
chr1_+_11796126 0.24 ENST00000376637.3
AGTRAP
angiotensin II receptor-associated protein
chr3_+_44379611 0.23 ENST00000383746.3
ENST00000417237.1
TCAIM
T cell activation inhibitor, mitochondrial
chr11_+_125757556 0.23 ENST00000526028.1
HYLS1
hydrolethalus syndrome 1
chr11_+_64126614 0.21 ENST00000528057.1
ENST00000334205.4
ENST00000294261.4
RPS6KA4
ribosomal protein S6 kinase, 90kDa, polypeptide 4
chr3_+_127771212 0.21 ENST00000243253.3
ENST00000481210.1
SEC61A1
Sec61 alpha 1 subunit (S. cerevisiae)
chr16_-_14788526 0.21 ENST00000438167.3
PLA2G10
phospholipase A2, group X
chr15_-_89456593 0.20 ENST00000558029.1
ENST00000539437.1
ENST00000542878.1
ENST00000268151.7
ENST00000566497.1
MFGE8
milk fat globule-EGF factor 8 protein
chr9_-_95527079 0.20 ENST00000356884.6
ENST00000375512.3
BICD2
bicaudal D homolog 2 (Drosophila)
chr1_+_32671236 0.20 ENST00000537469.1
ENST00000291358.6
IQCC
IQ motif containing C
chr19_+_35849723 0.20 ENST00000594310.1
FFAR3
free fatty acid receptor 3
chr20_+_30946106 0.20 ENST00000375687.4
ENST00000542461.1
ASXL1
additional sex combs like 1 (Drosophila)
chr19_+_45174724 0.20 ENST00000358777.4
CEACAM19
carcinoembryonic antigen-related cell adhesion molecule 19
chr20_+_43595115 0.19 ENST00000372806.3
ENST00000396731.4
ENST00000372801.1
ENST00000499879.2
STK4
serine/threonine kinase 4
chr7_-_56101826 0.19 ENST00000421626.1
PSPH
phosphoserine phosphatase
chr19_+_45174994 0.19 ENST00000403660.3
CEACAM19
carcinoembryonic antigen-related cell adhesion molecule 19
chr19_+_17982747 0.19 ENST00000222248.3
SLC5A5
solute carrier family 5 (sodium/iodide cotransporter), member 5
chr7_-_74221288 0.19 ENST00000451013.2
GTF2IRD2
GTF2I repeat domain containing 2
chr16_-_4303767 0.19 ENST00000573268.1
ENST00000573042.1
RP11-95P2.1
RP11-95P2.1
chr17_-_37308824 0.19 ENST00000415163.1
ENST00000441877.1
ENST00000444911.2
PLXDC1
plexin domain containing 1
chr17_-_74528128 0.19 ENST00000590175.1
CYGB
cytoglobin
chr5_+_162864575 0.18 ENST00000512163.1
ENST00000393929.1
ENST00000340828.2
ENST00000511683.2
ENST00000510097.1
ENST00000511490.2
ENST00000510664.1
CCNG1
cyclin G1
chr7_-_150924121 0.18 ENST00000441774.1
ENST00000222388.2
ENST00000287844.2
ABCF2
ATP-binding cassette, sub-family F (GCN20), member 2
chr1_-_156710859 0.18 ENST00000361531.2
ENST00000412846.1
MRPL24
mitochondrial ribosomal protein L24
chr10_+_96305535 0.18 ENST00000419900.1
ENST00000348459.5
ENST00000394045.1
ENST00000394044.1
ENST00000394036.1
HELLS
helicase, lymphoid-specific
chr7_+_75024903 0.18 ENST00000323819.3
ENST00000430211.1
TRIM73
tripartite motif containing 73
chr20_-_43589109 0.17 ENST00000372813.3
TOMM34
translocase of outer mitochondrial membrane 34
chr17_-_72855989 0.17 ENST00000293190.5
GRIN2C
glutamate receptor, ionotropic, N-methyl D-aspartate 2C
chr7_+_72742178 0.17 ENST00000442793.1
ENST00000413573.2
ENST00000252037.4
FKBP6
FK506 binding protein 6, 36kDa
chr17_-_37309480 0.17 ENST00000539608.1
PLXDC1
plexin domain containing 1
chr2_+_85661918 0.17 ENST00000340326.2
SH2D6
SH2 domain containing 6
chr12_+_54519842 0.17 ENST00000508564.1
RP11-834C11.4
RP11-834C11.4
chr19_+_38865398 0.17 ENST00000585598.1
ENST00000602911.1
ENST00000592561.1
PSMD8
proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
chr10_-_71993176 0.17 ENST00000373232.3
PPA1
pyrophosphatase (inorganic) 1
chr12_-_55042140 0.16 ENST00000293371.6
ENST00000456047.2
DCD
dermcidin
chr16_+_2079637 0.16 ENST00000561844.1
SLC9A3R2
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
chr1_-_243418621 0.16 ENST00000366544.1
ENST00000366543.1
CEP170
centrosomal protein 170kDa
chr9_+_116037922 0.16 ENST00000374198.4
PRPF4
pre-mRNA processing factor 4
chr1_+_25598989 0.16 ENST00000454452.2
RHD
Rh blood group, D antigen
chr7_+_72742162 0.16 ENST00000431982.2
FKBP6
FK506 binding protein 6, 36kDa
chr2_+_233734994 0.16 ENST00000331342.2
C2orf82
chromosome 2 open reading frame 82
chr1_-_6453399 0.16 ENST00000608083.1
ACOT7
acyl-CoA thioesterase 7
chr11_-_65626797 0.15 ENST00000525451.2
CFL1
cofilin 1 (non-muscle)
chr7_+_116165754 0.15 ENST00000405348.1
CAV1
caveolin 1, caveolae protein, 22kDa
chr14_-_50999307 0.15 ENST00000013125.4
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr14_+_69726656 0.15 ENST00000337827.4
GALNT16
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
chr3_+_148457585 0.15 ENST00000402260.1
AGTR1
angiotensin II receptor, type 1
chr18_-_28622699 0.15 ENST00000360428.4
DSC3
desmocollin 3
chr19_-_52150053 0.15 ENST00000599649.1
ENST00000429354.3
ENST00000360844.6
ENST00000222107.4
SIGLEC5
SIGLEC14
SIGLEC5
SIGLEC5
sialic acid binding Ig-like lectin 14
sialic acid binding Ig-like lectin 5
chr1_-_156710916 0.15 ENST00000368211.4
MRPL24
mitochondrial ribosomal protein L24
chr18_-_28622774 0.15 ENST00000434452.1
DSC3
desmocollin 3
chr11_+_60699222 0.15 ENST00000536409.1
TMEM132A
transmembrane protein 132A
chr8_-_12051576 0.15 ENST00000524571.2
ENST00000533852.2
ENST00000533513.1
ENST00000448228.2
ENST00000534520.1
ENST00000321602.8
FAM86B1
family with sequence similarity 86, member B1
chr3_+_196466710 0.14 ENST00000327134.3
PAK2
p21 protein (Cdc42/Rac)-activated kinase 2
chr3_+_14166440 0.14 ENST00000306077.4
TMEM43
transmembrane protein 43
chr1_+_211432700 0.14 ENST00000452621.2
RCOR3
REST corepressor 3
chr5_+_141348640 0.14 ENST00000540015.1
ENST00000506938.1
ENST00000394514.2
ENST00000512565.1
ENST00000394515.3
RNF14
ring finger protein 14
chr17_+_14204389 0.14 ENST00000360954.2
HS3ST3B1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr19_-_5567996 0.14 ENST00000448587.1
TINCR
tissue differentiation-inducing non-protein coding RNA
chr11_+_61717535 0.14 ENST00000534553.1
ENST00000301774.9
BEST1
bestrophin 1
chr14_+_50999744 0.13 ENST00000441560.2
ATL1
atlastin GTPase 1
chr1_+_28206150 0.13 ENST00000456990.1
THEMIS2
thymocyte selection associated family member 2
chr2_-_176032843 0.13 ENST00000392544.1
ENST00000409499.1
ENST00000426833.3
ENST00000392543.2
ENST00000538946.1
ENST00000487334.2
ENST00000409833.1
ENST00000409635.1
ENST00000264110.2
ENST00000345739.5
ATF2
activating transcription factor 2
chr11_-_44972418 0.13 ENST00000525680.1
ENST00000528290.1
ENST00000530035.1
TP53I11
tumor protein p53 inducible protein 11
chr11_-_108464321 0.13 ENST00000265843.4
EXPH5
exophilin 5
chr4_-_159644507 0.13 ENST00000307720.3
PPID
peptidylprolyl isomerase D
chr4_+_153457404 0.13 ENST00000604157.1
ENST00000594836.1
MIR4453
microRNA 4453
chr22_+_37447771 0.13 ENST00000402077.3
ENST00000403888.3
ENST00000456470.1
KCTD17
potassium channel tetramerization domain containing 17
chr11_+_36397528 0.13 ENST00000311599.5
ENST00000378867.3
PRR5L
proline rich 5 like
chr2_-_37193606 0.12 ENST00000379213.2
ENST00000263918.4
STRN
striatin, calmodulin binding protein
chr5_+_72861560 0.12 ENST00000296792.4
ENST00000509005.1
ENST00000543251.1
ENST00000508686.1
ENST00000508491.1
UTP15
UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae)
chr20_-_23807358 0.12 ENST00000304725.2
CST2
cystatin SA
chr9_+_119449576 0.12 ENST00000450136.1
ENST00000373983.2
ENST00000411410.1
TRIM32
tripartite motif containing 32
chr10_+_47746929 0.12 ENST00000340243.6
ENST00000374277.5
ENST00000449464.2
ENST00000538825.1
ENST00000335083.5
ANXA8L2
AL603965.1
annexin A8-like 2
Protein LOC100996760
chr4_-_153457197 0.12 ENST00000281708.4
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr12_+_12966250 0.11 ENST00000352940.4
ENST00000358007.3
ENST00000544400.1
DDX47
DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
chr16_+_30207122 0.11 ENST00000395137.2
SULT1A3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr3_-_113465065 0.11 ENST00000497255.1
ENST00000478020.1
ENST00000240922.3
ENST00000493900.1
NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr22_+_42949925 0.11 ENST00000327678.5
ENST00000340239.4
ENST00000407614.4
ENST00000335879.5
SERHL2
serine hydrolase-like 2
chr10_-_88854518 0.11 ENST00000277865.4
GLUD1
glutamate dehydrogenase 1
chr12_-_126467906 0.11 ENST00000507313.1
ENST00000545784.1
LINC00939
long intergenic non-protein coding RNA 939
chr22_-_36924944 0.11 ENST00000405442.1
ENST00000402116.1
EIF3D
eukaryotic translation initiation factor 3, subunit D
chr3_-_52001448 0.11 ENST00000461554.1
ENST00000395013.3
ENST00000428823.2
ENST00000483411.1
ENST00000461544.1
ENST00000355852.2
PCBP4
poly(rC) binding protein 4
chr2_-_11484710 0.11 ENST00000315872.6
ROCK2
Rho-associated, coiled-coil containing protein kinase 2
chr20_+_5451845 0.11 ENST00000430097.2
RP5-828H9.1
RP5-828H9.1
chr1_-_1243252 0.11 ENST00000353662.3
ACAP3
ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
chr19_-_14228541 0.10 ENST00000590853.1
ENST00000308677.4
PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
chr7_+_23145366 0.10 ENST00000339077.5
ENST00000322275.5
ENST00000539124.1
ENST00000542558.1
KLHL7
kelch-like family member 7
chr12_+_124086632 0.10 ENST00000238146.4
ENST00000538744.1
DDX55
DEAD (Asp-Glu-Ala-Asp) box polypeptide 55
chr2_+_95691417 0.10 ENST00000309988.4
MAL
mal, T-cell differentiation protein
chrX_-_153285251 0.10 ENST00000444230.1
ENST00000393682.1
ENST00000393687.2
ENST00000429936.2
ENST00000369974.2
IRAK1
interleukin-1 receptor-associated kinase 1
chr22_-_36925186 0.10 ENST00000541106.1
ENST00000455547.1
ENST00000432675.1
EIF3D
eukaryotic translation initiation factor 3, subunit D
chr1_-_1243392 0.10 ENST00000354700.5
ACAP3
ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
chr5_+_71014990 0.10 ENST00000296777.4
CARTPT
CART prepropeptide
chr2_+_179345173 0.10 ENST00000234453.5
PLEKHA3
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3
chr19_-_47551836 0.10 ENST00000253047.6
TMEM160
transmembrane protein 160
chr2_+_47168630 0.10 ENST00000263737.6
TTC7A
tetratricopeptide repeat domain 7A
chr1_+_116519112 0.10 ENST00000369503.4
SLC22A15
solute carrier family 22, member 15
chr2_+_113829895 0.10 ENST00000393197.2
IL1F10
interleukin 1 family, member 10 (theta)

Network of associatons between targets according to the STRING database.

First level regulatory network of TP53

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.5 2.0 GO:2000564 CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.5 1.9 GO:0016334 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.4 1.1 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
0.3 0.8 GO:0046521 sphingoid catabolic process(GO:0046521)
0.2 0.7 GO:1904328 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.2 0.7 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.2 0.6 GO:0071301 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.2 1.0 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956)
0.2 1.2 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.2 1.1 GO:0046208 spermine catabolic process(GO:0046208)
0.2 0.5 GO:1904747 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597) apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) positive regulation of apoptotic DNA fragmentation(GO:1902512) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.2 0.5 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.2 1.0 GO:0036337 Fas signaling pathway(GO:0036337)
0.2 0.5 GO:2000097 chronological cell aging(GO:0001300) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 0.8 GO:0090131 mesenchyme migration(GO:0090131)
0.1 0.3 GO:0071879 UDP-glucose catabolic process(GO:0006258) positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.1 1.0 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.1 2.2 GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.1 0.7 GO:0008218 bioluminescence(GO:0008218)
0.1 0.5 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.1 0.3 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 0.8 GO:0010918 positive regulation of mitochondrial membrane potential(GO:0010918)
0.1 1.2 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.1 1.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 0.3 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1 1.0 GO:0010917 negative regulation of mitochondrial membrane potential(GO:0010917)
0.1 0.9 GO:0022417 protein maturation by protein folding(GO:0022417)
0.1 0.2 GO:0039019 pronephric nephron development(GO:0039019)
0.1 0.5 GO:2000814 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.1 0.2 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.1 0.2 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 0.4 GO:0042816 vitamin B6 metabolic process(GO:0042816)
0.1 0.2 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.1 0.4 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 0.3 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 0.7 GO:0002934 desmosome organization(GO:0002934)
0.0 0.2 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.0 0.1 GO:0061198 fungiform papilla formation(GO:0061198)
0.0 0.7 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 0.2 GO:0036116 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.0 0.2 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 0.2 GO:0071344 diphosphate metabolic process(GO:0071344)
0.0 0.2 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.2 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.8 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.5 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.1 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.8 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0 0.4 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.0 0.1 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
0.0 0.4 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 0.2 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.5 GO:0001553 luteinization(GO:0001553)
0.0 0.7 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.2 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.0 0.2 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.8 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.6 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.1 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.1 GO:0030047 actin modification(GO:0030047)
0.0 0.1 GO:0045007 depurination(GO:0045007)
0.0 0.6 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.3 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 0.1 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.1 GO:0060313 negative regulation of blood vessel remodeling(GO:0060313)
0.0 0.8 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.2 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.1 GO:0006272 leading strand elongation(GO:0006272)
0.0 0.1 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.0 1.5 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.4 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 0.4 GO:0044126 regulation of growth of symbiont in host(GO:0044126)
0.0 0.1 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.6 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.2 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.1 GO:1900138 negative regulation of phospholipase A2 activity(GO:1900138)
0.0 0.1 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.0 0.1 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.0 0.2 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.3 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.1 GO:0032906 transforming growth factor beta2 production(GO:0032906) regulation of transforming growth factor beta2 production(GO:0032909)
0.0 0.4 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.1 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.0 0.3 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.3 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.1 GO:0072402 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.0 0.3 GO:0019054 modulation by virus of host process(GO:0019054)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.9 GO:0042643 actomyosin, actin portion(GO:0042643)
0.2 0.9 GO:1990425 ryanodine receptor complex(GO:1990425)
0.1 0.8 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.8 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 0.9 GO:0005638 lamin filament(GO:0005638)
0.1 0.8 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.6 GO:0036021 endolysosome lumen(GO:0036021)
0.1 1.0 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.7 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.9 GO:0016600 flotillin complex(GO:0016600)
0.0 0.4 GO:0031415 NatA complex(GO:0031415)
0.0 1.0 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.5 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.2 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.2 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.1 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 1.0 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0043293 apoptosome(GO:0043293)
0.0 0.3 GO:0071439 clathrin complex(GO:0071439)
0.0 0.2 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.9 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.0 0.8 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.5 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:1990769 proximal neuron projection(GO:1990769)
0.0 1.1 GO:0034707 chloride channel complex(GO:0034707)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.4 2.5 GO:0045569 TRAIL binding(GO:0045569)
0.4 1.1 GO:0004817 cysteine-tRNA ligase activity(GO:0004817)
0.4 1.1 GO:0052894 norspermine:oxygen oxidoreductase activity(GO:0052894) N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity(GO:0052895)
0.2 0.6 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.2 1.4 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.1 0.4 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.1 0.5 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.1 0.8 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.7 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.1 0.2 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.4 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 0.2 GO:0098808 mRNA cap binding(GO:0098808)
0.1 0.6 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.1 0.3 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.9 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 0.7 GO:0008517 folic acid transporter activity(GO:0008517)
0.1 0.6 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.3 GO:0016900 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.1 0.2 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.1 0.8 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 2.1 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.2 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 0.5 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.4 GO:0008142 oxysterol binding(GO:0008142)
0.0 1.1 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.2 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.0 0.2 GO:0000701 purine-specific mismatch base pair DNA N-glycosylase activity(GO:0000701)
0.0 0.3 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.2 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.2 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.5 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.4 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.6 GO:0031005 filamin binding(GO:0031005)
0.0 0.8 GO:0005123 death receptor binding(GO:0005123)
0.0 0.2 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.2 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.0 0.7 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.2 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.9 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.3 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.8 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.9 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.4 GO:0022840 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.0 0.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.2 GO:0034452 dynactin binding(GO:0034452)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)
0.0 0.4 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 2.9 GO:0051015 actin filament binding(GO:0051015)
0.0 0.1 GO:0015386 potassium:proton antiporter activity(GO:0015386)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 2.3 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.9 PID ALK2 PATHWAY ALK2 signaling events
0.0 2.5 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.8 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.9 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.5 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.6 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.7 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 3.3 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 1.1 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.9 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.1 PID S1P S1P2 PATHWAY S1P2 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.1 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 2.6 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 0.6 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 1.0 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 1.6 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 1.1 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.6 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.9 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 1.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 2.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.7 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 1.0 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.7 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.8 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.5 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.2 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.3 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 2.1 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.3 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.2 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor