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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for TP63

Z-value: 0.52

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Transcription factors associated with TP63

Gene Symbol Gene ID Gene Info
TP63
ENSG00000073282.8 tumor protein p63

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TP63hg19_v2_chr3_+_189507523_1895075900.252.3e-01Click!

Activity profile of TP63 motif

Sorted Z-values of TP63 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_57653989 1.29 ENST00000567835.1
ENST00000569372.1
ENST00000563548.1
ENST00000562003.1
GPR56
G protein-coupled receptor 56
chr16_+_57653854 1.23 ENST00000568908.1
ENST00000568909.1
ENST00000566778.1
ENST00000561988.1
GPR56
G protein-coupled receptor 56
chr18_+_57567180 0.97 ENST00000316660.6
ENST00000269518.9
PMAIP1
phorbol-12-myristate-13-acetate-induced protein 1
chr10_+_90750493 0.87 ENST00000357339.2
ENST00000355279.2
FAS
Fas cell surface death receptor
chr10_-_90751038 0.81 ENST00000458159.1
ENST00000415557.1
ENST00000458208.1
ACTA2
actin, alpha 2, smooth muscle, aorta
chr17_+_26662597 0.81 ENST00000544907.2
TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr17_+_26662730 0.67 ENST00000226225.2
TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr8_-_22926526 0.60 ENST00000347739.3
ENST00000542226.1
TNFRSF10B
tumor necrosis factor receptor superfamily, member 10b
chr14_+_51955831 0.55 ENST00000356218.4
FRMD6
FERM domain containing 6
chr2_+_131369054 0.55 ENST00000409602.1
POTEJ
POTE ankyrin domain family, member J
chr12_-_15114658 0.52 ENST00000542276.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr6_-_101329157 0.51 ENST00000369143.2
ASCC3
activating signal cointegrator 1 complex subunit 3
chr19_-_15235906 0.50 ENST00000600984.1
ILVBL
ilvB (bacterial acetolactate synthase)-like
chr4_+_8321882 0.49 ENST00000509453.1
ENST00000503186.1
RP11-774O3.2
RP11-774O3.1
RP11-774O3.2
RP11-774O3.1
chr12_-_88974236 0.45 ENST00000228280.5
ENST00000552044.1
ENST00000357116.4
KITLG
KIT ligand
chr11_-_75017734 0.44 ENST00000532525.1
ARRB1
arrestin, beta 1
chr15_-_89456630 0.43 ENST00000268150.8
MFGE8
milk fat globule-EGF factor 8 protein
chr12_-_15114492 0.42 ENST00000541546.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr8_-_22926623 0.41 ENST00000276431.4
TNFRSF10B
tumor necrosis factor receptor superfamily, member 10b
chr1_-_209824643 0.41 ENST00000391911.1
ENST00000415782.1
LAMB3
laminin, beta 3
chr6_+_106546808 0.41 ENST00000369089.3
PRDM1
PR domain containing 1, with ZNF domain
chr22_+_39378346 0.41 ENST00000407298.3
APOBEC3B
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
chr1_-_46089639 0.39 ENST00000445048.2
CCDC17
coiled-coil domain containing 17
chrX_+_152086373 0.37 ENST00000318529.8
ZNF185
zinc finger protein 185 (LIM domain)
chr6_+_55039050 0.37 ENST00000370862.3
HCRTR2
hypocretin (orexin) receptor 2
chr10_+_99344104 0.37 ENST00000555577.1
ENST00000370649.3
PI4K2A
PI4K2A
phosphatidylinositol 4-kinase type 2 alpha
Phosphatidylinositol 4-kinase type 2-alpha; Uncharacterized protein
chr19_+_35849362 0.35 ENST00000327809.4
FFAR3
free fatty acid receptor 3
chr4_-_7436671 0.34 ENST00000319098.4
PSAPL1
prosaposin-like 1 (gene/pseudogene)
chr14_+_22636283 0.33 ENST00000557168.1
TRAV30
T cell receptor alpha variable 30
chr12_-_15114603 0.33 ENST00000228945.4
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr1_+_12040238 0.33 ENST00000444836.1
ENST00000235329.5
MFN2
mitofusin 2
chr16_+_23652773 0.33 ENST00000563998.1
ENST00000568589.1
ENST00000568272.1
DCTN5
dynactin 5 (p25)
chr19_-_47734448 0.32 ENST00000439096.2
BBC3
BCL2 binding component 3
chr8_+_126442563 0.32 ENST00000311922.3
TRIB1
tribbles pseudokinase 1
chr16_-_68000717 0.32 ENST00000541864.2
SLC12A4
solute carrier family 12 (potassium/chloride transporter), member 4
chr5_-_156390230 0.32 ENST00000407087.3
ENST00000274532.2
TIMD4
T-cell immunoglobulin and mucin domain containing 4
chr12_+_69202795 0.31 ENST00000539479.1
ENST00000393415.3
ENST00000523991.1
ENST00000543323.1
ENST00000393416.2
MDM2
MDM2 oncogene, E3 ubiquitin protein ligase
chr1_+_3607228 0.31 ENST00000378285.1
ENST00000378280.1
ENST00000378288.4
TP73
tumor protein p73
chr11_-_72432950 0.31 ENST00000426523.1
ENST00000429686.1
ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr10_+_124134201 0.31 ENST00000368990.3
ENST00000368988.1
ENST00000368989.2
ENST00000463663.2
PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr19_+_35862192 0.31 ENST00000597214.1
GPR42
G protein-coupled receptor 42 (gene/pseudogene)
chr19_+_35861831 0.30 ENST00000454971.1
GPR42
G protein-coupled receptor 42 (gene/pseudogene)
chr2_-_165698662 0.30 ENST00000194871.6
ENST00000445474.2
COBLL1
cordon-bleu WH2 repeat protein-like 1
chr19_+_35849723 0.30 ENST00000594310.1
FFAR3
free fatty acid receptor 3
chr15_-_72523924 0.29 ENST00000566809.1
ENST00000567087.1
ENST00000569050.1
ENST00000568883.1
PKM
pyruvate kinase, muscle
chr8_+_22960426 0.28 ENST00000540813.1
TNFRSF10C
tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
chr15_-_89456593 0.27 ENST00000558029.1
ENST00000539437.1
ENST00000542878.1
ENST00000268151.7
ENST00000566497.1
MFGE8
milk fat globule-EGF factor 8 protein
chr21_-_27462351 0.27 ENST00000448850.1
APP
amyloid beta (A4) precursor protein
chr19_+_48824711 0.26 ENST00000599704.1
EMP3
epithelial membrane protein 3
chr6_+_127898312 0.26 ENST00000329722.7
C6orf58
chromosome 6 open reading frame 58
chr17_+_80332153 0.26 ENST00000313135.2
UTS2R
urotensin 2 receptor
chr2_-_47168850 0.26 ENST00000409207.1
MCFD2
multiple coagulation factor deficiency 2
chr2_+_108994466 0.25 ENST00000272452.2
SULT1C4
sulfotransferase family, cytosolic, 1C, member 4
chr11_-_111782484 0.25 ENST00000533971.1
CRYAB
crystallin, alpha B
chr7_+_100466433 0.25 ENST00000429658.1
TRIP6
thyroid hormone receptor interactor 6
chr12_+_69202975 0.25 ENST00000544561.1
ENST00000393410.1
ENST00000299252.4
ENST00000360430.2
ENST00000517852.1
ENST00000545204.1
ENST00000393413.3
ENST00000350057.5
ENST00000348801.2
ENST00000478070.1
MDM2
MDM2 oncogene, E3 ubiquitin protein ligase
chr4_+_3388057 0.24 ENST00000538395.1
RGS12
regulator of G-protein signaling 12
chr1_-_150738261 0.24 ENST00000448301.2
ENST00000368985.3
CTSS
cathepsin S
chr2_+_69201705 0.23 ENST00000377938.2
GKN1
gastrokine 1
chrX_-_70838306 0.23 ENST00000373691.4
ENST00000373693.3
CXCR3
chemokine (C-X-C motif) receptor 3
chr12_-_15114191 0.21 ENST00000541380.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr6_-_101329191 0.21 ENST00000324723.6
ENST00000369162.2
ENST00000522650.1
ASCC3
activating signal cointegrator 1 complex subunit 3
chr10_+_5726764 0.21 ENST00000328090.5
ENST00000496681.1
FAM208B
family with sequence similarity 208, member B
chr19_+_18496957 0.20 ENST00000252809.3
GDF15
growth differentiation factor 15
chr8_-_23021533 0.20 ENST00000312584.3
TNFRSF10D
tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
chr14_-_94595993 0.20 ENST00000238609.3
IFI27L2
interferon, alpha-inducible protein 27-like 2
chr11_-_65686586 0.20 ENST00000438576.2
C11orf68
chromosome 11 open reading frame 68
chr19_+_49497121 0.20 ENST00000413176.2
RUVBL2
RuvB-like AAA ATPase 2
chr19_-_10420459 0.20 ENST00000403352.1
ENST00000403903.3
ZGLP1
zinc finger, GATA-like protein 1
chr11_-_65686496 0.19 ENST00000449692.3
C11orf68
chromosome 11 open reading frame 68
chr14_-_98444386 0.19 ENST00000556462.1
ENST00000556138.1
C14orf64
chromosome 14 open reading frame 64
chr3_+_44379611 0.19 ENST00000383746.3
ENST00000417237.1
TCAIM
T cell activation inhibitor, mitochondrial
chr1_+_42619070 0.19 ENST00000372581.1
GUCA2B
guanylate cyclase activator 2B (uroguanylin)
chr18_-_40857493 0.19 ENST00000255224.3
SYT4
synaptotagmin IV
chr1_+_114447763 0.18 ENST00000369563.3
DCLRE1B
DNA cross-link repair 1B
chr5_+_179247759 0.18 ENST00000389805.4
ENST00000504627.1
ENST00000402874.3
ENST00000510187.1
SQSTM1
sequestosome 1
chr19_+_44081344 0.18 ENST00000599207.1
PINLYP
phospholipase A2 inhibitor and LY6/PLAUR domain containing
chr4_+_671711 0.18 ENST00000400159.2
MYL5
myosin, light chain 5, regulatory
chr5_+_180326077 0.18 ENST00000231229.4
ENST00000340184.4
ENST00000400707.3
BTNL8
butyrophilin-like 8
chr11_-_1330834 0.18 ENST00000525159.1
ENST00000317204.6
ENST00000542915.1
ENST00000527938.1
ENST00000530541.1
ENST00000263646.7
TOLLIP
toll interacting protein
chr16_-_70729496 0.18 ENST00000567648.1
VAC14
Vac14 homolog (S. cerevisiae)
chr20_+_30467600 0.18 ENST00000375934.4
ENST00000375922.4
TTLL9
tubulin tyrosine ligase-like family, member 9
chr20_+_816695 0.18 ENST00000246100.3
FAM110A
family with sequence similarity 110, member A
chr2_-_165698521 0.17 ENST00000409184.3
ENST00000392717.2
ENST00000456693.1
COBLL1
cordon-bleu WH2 repeat protein-like 1
chrX_-_24045303 0.17 ENST00000328046.8
KLHL15
kelch-like family member 15
chr1_+_160336851 0.17 ENST00000302101.5
NHLH1
nescient helix loop helix 1
chr1_+_17575584 0.17 ENST00000375460.3
PADI3
peptidyl arginine deiminase, type III
chr7_+_142636440 0.17 ENST00000458732.1
C7orf34
chromosome 7 open reading frame 34
chr19_+_17982747 0.16 ENST00000222248.3
SLC5A5
solute carrier family 5 (sodium/iodide cotransporter), member 5
chr19_-_11688447 0.16 ENST00000590420.1
ACP5
acid phosphatase 5, tartrate resistant
chr21_+_43823983 0.16 ENST00000291535.6
ENST00000450356.1
ENST00000319294.6
ENST00000398367.1
UBASH3A
ubiquitin associated and SH3 domain containing A
chr19_-_3500635 0.16 ENST00000250937.3
DOHH
deoxyhypusine hydroxylase/monooxygenase
chr16_+_30007524 0.16 ENST00000567254.1
ENST00000567705.1
INO80E
INO80 complex subunit E
chr2_-_178257401 0.16 ENST00000464747.1
NFE2L2
nuclear factor, erythroid 2-like 2
chr1_+_38158090 0.15 ENST00000373055.1
ENST00000327331.2
CDCA8
cell division cycle associated 8
chr11_-_8190534 0.15 ENST00000309737.6
ENST00000425599.2
ENST00000539720.1
ENST00000531450.1
ENST00000419822.2
ENST00000335425.7
ENST00000343202.4
RIC3
RIC3 acetylcholine receptor chaperone
chr11_+_18433840 0.15 ENST00000541669.1
ENST00000280704.4
LDHC
lactate dehydrogenase C
chr12_-_55042140 0.15 ENST00000293371.6
ENST00000456047.2
DCD
dermcidin
chr22_+_31489344 0.15 ENST00000404574.1
SMTN
smoothelin
chr4_-_10023095 0.15 ENST00000264784.3
SLC2A9
solute carrier family 2 (facilitated glucose transporter), member 9
chr17_-_61959202 0.15 ENST00000449787.2
ENST00000456543.2
ENST00000423893.2
ENST00000332800.7
GH2
growth hormone 2
chr5_+_162864575 0.15 ENST00000512163.1
ENST00000393929.1
ENST00000340828.2
ENST00000511683.2
ENST00000510097.1
ENST00000511490.2
ENST00000510664.1
CCNG1
cyclin G1
chr16_+_1832902 0.15 ENST00000262302.9
ENST00000563136.1
ENST00000565987.1
ENST00000543305.1
ENST00000568287.1
ENST00000565134.1
NUBP2
nucleotide binding protein 2
chr19_+_49458107 0.15 ENST00000539787.1
ENST00000345358.7
ENST00000391871.3
ENST00000415969.2
ENST00000354470.3
ENST00000506183.1
ENST00000293288.8
BAX
BCL2-associated X protein
chr22_+_38302285 0.15 ENST00000215957.6
MICALL1
MICAL-like 1
chr1_-_118727781 0.14 ENST00000336338.5
SPAG17
sperm associated antigen 17
chr11_+_125757556 0.14 ENST00000526028.1
HYLS1
hydrolethalus syndrome 1
chr7_-_142207004 0.14 ENST00000426318.2
TRBV10-2
T cell receptor beta variable 10-2
chr18_+_34124507 0.14 ENST00000591635.1
FHOD3
formin homology 2 domain containing 3
chr12_-_122712038 0.14 ENST00000413918.1
ENST00000443649.3
DIABLO
diablo, IAP-binding mitochondrial protein
chr5_-_169626104 0.14 ENST00000520275.1
ENST00000506431.2
CTB-27N1.1
CTB-27N1.1
chr11_-_77850629 0.14 ENST00000376156.3
ENST00000525870.1
ENST00000530454.1
ENST00000525755.1
ENST00000527099.1
ENST00000525761.1
ENST00000299626.5
ALG8
ALG8, alpha-1,3-glucosyltransferase
chr17_+_75450075 0.13 ENST00000592951.1
SEPT9
septin 9
chr7_-_112430427 0.13 ENST00000449743.1
ENST00000441474.1
ENST00000454074.1
ENST00000447395.1
TMEM168
transmembrane protein 168
chr3_+_152552685 0.13 ENST00000305097.3
P2RY1
purinergic receptor P2Y, G-protein coupled, 1
chr15_+_68570062 0.13 ENST00000306917.4
FEM1B
fem-1 homolog b (C. elegans)
chr16_+_56995762 0.12 ENST00000200676.3
ENST00000379780.2
CETP
cholesteryl ester transfer protein, plasma
chr15_-_72767490 0.12 ENST00000565181.1
RP11-1007O24.3
RP11-1007O24.3
chr1_+_22303503 0.12 ENST00000337107.6
CELA3B
chymotrypsin-like elastase family, member 3B
chr16_+_30006997 0.12 ENST00000304516.7
INO80E
INO80 complex subunit E
chr10_+_82298088 0.12 ENST00000470604.2
SH2D4B
SH2 domain containing 4B
chr12_+_119616447 0.12 ENST00000281938.2
HSPB8
heat shock 22kDa protein 8
chr6_+_31633833 0.12 ENST00000375882.2
ENST00000375880.2
CSNK2B
CSNK2B-LY6G5B-1181
casein kinase 2, beta polypeptide
Uncharacterized protein
chr16_+_67034466 0.12 ENST00000535696.1
CES4A
carboxylesterase 4A
chr18_+_55018044 0.12 ENST00000324000.3
ST8SIA3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr6_-_109330702 0.12 ENST00000356644.7
SESN1
sestrin 1
chr20_+_4129426 0.12 ENST00000339123.6
ENST00000305958.4
ENST00000278795.3
SMOX
spermine oxidase
chr20_+_34894247 0.12 ENST00000373913.3
DLGAP4
discs, large (Drosophila) homolog-associated protein 4
chr2_+_68384976 0.12 ENST00000263657.2
PNO1
partner of NOB1 homolog (S. cerevisiae)
chrX_-_129244655 0.12 ENST00000335997.7
ELF4
E74-like factor 4 (ets domain transcription factor)
chr15_+_69857515 0.12 ENST00000559477.1
RP11-279F6.1
RP11-279F6.1
chrX_+_72667090 0.12 ENST00000373514.2
CDX4
caudal type homeobox 4
chr9_+_116298778 0.11 ENST00000462143.1
RGS3
regulator of G-protein signaling 3
chr1_+_17906970 0.11 ENST00000375415.1
ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr10_-_89623194 0.11 ENST00000445946.3
KLLN
killin, p53-regulated DNA replication inhibitor
chr20_+_57264187 0.11 ENST00000525967.1
ENST00000525817.1
NPEPL1
aminopeptidase-like 1
chr19_+_507299 0.11 ENST00000359315.5
TPGS1
tubulin polyglutamylase complex subunit 1
chr11_-_36310958 0.11 ENST00000532705.1
ENST00000263401.5
ENST00000452374.2
COMMD9
COMM domain containing 9
chrX_-_129244454 0.11 ENST00000308167.5
ELF4
E74-like factor 4 (ets domain transcription factor)
chr18_-_49557 0.11 ENST00000308911.6
RP11-683L23.1
Tubulin beta-8 chain-like protein LOC260334
chr17_-_79212884 0.11 ENST00000300714.3
ENTHD2
ENTH domain containing 2
chr17_-_26662440 0.11 ENST00000578122.1
IFT20
intraflagellar transport 20 homolog (Chlamydomonas)
chr19_-_11688500 0.11 ENST00000433365.2
ACP5
acid phosphatase 5, tartrate resistant
chr17_-_79212825 0.11 ENST00000374769.2
ENTHD2
ENTH domain containing 2
chrX_+_48334549 0.11 ENST00000019019.2
ENST00000348411.2
ENST00000396894.4
FTSJ1
FtsJ RNA methyltransferase homolog 1 (E. coli)
chrX_+_48681768 0.11 ENST00000430858.1
HDAC6
histone deacetylase 6
chr4_+_95917383 0.11 ENST00000512312.1
BMPR1B
bone morphogenetic protein receptor, type IB
chr1_-_117753540 0.11 ENST00000328189.3
ENST00000369458.3
VTCN1
V-set domain containing T cell activation inhibitor 1
chr19_-_58090240 0.10 ENST00000196489.3
ZNF416
zinc finger protein 416
chr9_+_119449576 0.10 ENST00000450136.1
ENST00000373983.2
ENST00000411410.1
TRIM32
tripartite motif containing 32
chr17_+_4618734 0.10 ENST00000571206.1
ARRB2
arrestin, beta 2
chr3_+_47844399 0.10 ENST00000446256.2
ENST00000445061.1
DHX30
DEAH (Asp-Glu-Ala-His) box helicase 30
chr17_-_26662464 0.10 ENST00000579419.1
ENST00000585313.1
ENST00000395418.3
ENST00000578985.1
ENST00000577498.1
ENST00000585089.1
ENST00000357896.3
IFT20
intraflagellar transport 20 homolog (Chlamydomonas)
chr17_-_72709050 0.10 ENST00000583937.1
ENST00000301573.9
ENST00000326165.6
ENST00000469092.1
CD300LF
CD300 molecule-like family member f
chr16_+_30006615 0.10 ENST00000563197.1
INO80E
INO80 complex subunit E
chr17_-_14140166 0.10 ENST00000420162.2
ENST00000431716.2
CDRT15
CMT1A duplicated region transcript 15
chr12_+_49687425 0.10 ENST00000257860.4
PRPH
peripherin
chr2_-_74618964 0.10 ENST00000417090.1
ENST00000409868.1
DCTN1
dynactin 1
chr22_-_36924944 0.09 ENST00000405442.1
ENST00000402116.1
EIF3D
eukaryotic translation initiation factor 3, subunit D
chr11_-_18034430 0.09 ENST00000530613.1
ENST00000532389.1
ENST00000529728.1
ENST00000532265.1
SERGEF
secretion regulating guanine nucleotide exchange factor
chr5_-_94417314 0.09 ENST00000505208.1
MCTP1
multiple C2 domains, transmembrane 1
chr19_+_15160130 0.09 ENST00000427043.3
CASP14
caspase 14, apoptosis-related cysteine peptidase
chr20_-_6103666 0.09 ENST00000536936.1
FERMT1
fermitin family member 1
chr10_-_82049424 0.09 ENST00000372213.3
MAT1A
methionine adenosyltransferase I, alpha
chr16_+_23652700 0.09 ENST00000300087.2
DCTN5
dynactin 5 (p25)
chr11_-_414948 0.09 ENST00000530494.1
ENST00000528209.1
ENST00000431843.2
ENST00000528058.1
SIGIRR
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr15_-_63448973 0.09 ENST00000462430.1
RPS27L
ribosomal protein S27-like
chr2_+_47168313 0.09 ENST00000319190.5
ENST00000394850.2
ENST00000536057.1
TTC7A
tetratricopeptide repeat domain 7A
chr17_-_34079897 0.08 ENST00000254466.6
ENST00000587565.1
GAS2L2
growth arrest-specific 2 like 2
chr22_-_36925186 0.08 ENST00000541106.1
ENST00000455547.1
ENST00000432675.1
EIF3D
eukaryotic translation initiation factor 3, subunit D
chr18_+_21033239 0.08 ENST00000581585.1
ENST00000577501.1
RIOK3
RIO kinase 3
chr13_+_23755099 0.08 ENST00000537476.1
SGCG
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
chr11_+_67776012 0.08 ENST00000539229.1
ALDH3B1
aldehyde dehydrogenase 3 family, member B1
chr8_+_67341239 0.08 ENST00000320270.2
RRS1
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
chrX_-_138724677 0.08 ENST00000370573.4
ENST00000338585.6
ENST00000370576.4
MCF2
MCF.2 cell line derived transforming sequence
chr3_-_45017609 0.08 ENST00000342790.4
ENST00000424952.2
ENST00000296127.3
ENST00000455235.1
ZDHHC3
zinc finger, DHHC-type containing 3
chr5_-_42811986 0.08 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
SEPP1
selenoprotein P, plasma, 1
chr3_+_122044084 0.08 ENST00000264474.3
ENST00000479204.1
CSTA
cystatin A (stefin A)
chr20_-_43280361 0.08 ENST00000372874.4
ADA
adenosine deaminase
chr1_-_228603694 0.08 ENST00000366697.2
TRIM17
tripartite motif containing 17
chr9_-_136605042 0.08 ENST00000371872.4
ENST00000298628.5
ENST00000422262.2
SARDH
sarcosine dehydrogenase
chr17_-_72855989 0.08 ENST00000293190.5
GRIN2C
glutamate receptor, ionotropic, N-methyl D-aspartate 2C
chr12_-_52887034 0.08 ENST00000330722.6
KRT6A
keratin 6A
chr18_+_61144160 0.08 ENST00000489441.1
ENST00000424602.1
SERPINB5
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr20_-_43280325 0.08 ENST00000537820.1
ADA
adenosine deaminase
chr10_+_124913793 0.08 ENST00000368865.4
ENST00000538238.1
ENST00000368859.2
BUB3
BUB3 mitotic checkpoint protein
chr19_+_51293672 0.08 ENST00000270593.1
ENST00000270594.3
ACPT
acid phosphatase, testicular
chrX_-_111923145 0.08 ENST00000371968.3
ENST00000536453.1
LHFPL1
lipoma HMGIC fusion partner-like 1
chr3_-_149375783 0.08 ENST00000467467.1
ENST00000460517.1
ENST00000360632.3
WWTR1
WW domain containing transcription regulator 1
chr1_+_46152886 0.08 ENST00000372025.4
TMEM69
transmembrane protein 69
chr14_+_58754751 0.07 ENST00000598233.1
AL132989.1
AL132989.1
chr16_-_1020849 0.07 ENST00000568897.1
LMF1
lipase maturation factor 1
chrX_-_138724994 0.07 ENST00000536274.1
MCF2
MCF.2 cell line derived transforming sequence
chr2_+_169312725 0.07 ENST00000392687.4
CERS6
ceramide synthase 6
chr15_+_78558523 0.07 ENST00000446172.2
DNAJA4
DnaJ (Hsp40) homolog, subfamily A, member 4
chrX_+_2670066 0.07 ENST00000381174.5
ENST00000419513.2
ENST00000426774.1
XG
Xg blood group
chr3_-_49395892 0.07 ENST00000419783.1
GPX1
glutathione peroxidase 1
chr17_+_20483037 0.07 ENST00000399044.1
CDRT15L2
CMT1A duplicated region transcript 15-like 2
chr3_+_70048881 0.07 ENST00000483525.1
RP11-460N16.1
RP11-460N16.1
chr5_+_132009675 0.07 ENST00000231449.2
ENST00000350025.2
IL4
interleukin 4

Network of associatons between targets according to the STRING database.

First level regulatory network of TP63

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 GO:0071461 cellular response to redox state(GO:0071461)
0.2 0.6 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.2 0.6 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.2 0.5 GO:0033023 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.1 0.9 GO:0036337 Fas signaling pathway(GO:0036337)
0.1 0.8 GO:0090131 mesenchyme migration(GO:0090131)
0.1 0.4 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.1 0.3 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.1 0.6 GO:0010840 regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) circadian sleep/wake cycle, wakefulness(GO:0042746)
0.1 0.2 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.1 0.4 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.1 0.6 GO:0003383 apical constriction(GO:0003383)
0.1 0.3 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.1 1.0 GO:0010917 negative regulation of mitochondrial membrane potential(GO:0010917)
0.1 0.2 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.1 0.8 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.1 0.3 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.1 0.3 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.1 1.2 GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.1 0.2 GO:0046103 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.1 0.7 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.2 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 1.5 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.2 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.5 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.4 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.0 0.2 GO:0090579 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.0 0.6 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.2 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.2 GO:1903788 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0 0.2 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.2 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.1 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.4 GO:0010528 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.0 0.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.1 GO:1901053 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.0 0.1 GO:0072276 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.0 0.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.2 GO:0019249 lactate biosynthetic process(GO:0019249)
0.0 0.1 GO:0009609 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
0.0 0.3 GO:0009629 response to gravity(GO:0009629)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.2 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.3 GO:0001553 luteinization(GO:0001553)
0.0 0.1 GO:0030047 actin modification(GO:0030047)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.3 GO:0060742 epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.0 0.1 GO:0030860 neuroblast division in subventricular zone(GO:0021849) regulation of polarized epithelial cell differentiation(GO:0030860)
0.0 0.1 GO:0046208 spermine catabolic process(GO:0046208)
0.0 0.1 GO:0001897 cytolysis by symbiont of host cells(GO:0001897) regulation of cytolysis in other organism(GO:0051710)
0.0 0.2 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:0051884 negative regulation of hair follicle maturation(GO:0048817) regulation of anagen(GO:0051884)
0.0 0.1 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.0 0.1 GO:0070350 T-helper 1 cell lineage commitment(GO:0002296) white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350) cellular response to mercury ion(GO:0071288) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.1 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.0 0.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 0.3 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.2 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130)
0.0 0.2 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.1 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.2 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.1 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.3 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.1 GO:0035936 testosterone secretion(GO:0035936) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
0.0 0.2 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.1 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.2 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.2 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.1 GO:0007288 sperm axoneme assembly(GO:0007288) protein polyglutamylation(GO:0018095)
0.0 0.1 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.3 GO:0032060 bleb assembly(GO:0032060)
0.0 0.3 GO:0006884 cell volume homeostasis(GO:0006884)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.4 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.1 0.4 GO:0035838 growing cell tip(GO:0035838)
0.1 0.2 GO:1902636 kinociliary basal body(GO:1902636)
0.1 0.2 GO:0032127 dense core granule membrane(GO:0032127)
0.1 0.2 GO:0044753 amphisome(GO:0044753)
0.1 0.4 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.1 GO:1990716 axonemal central apparatus(GO:1990716)
0.0 0.1 GO:1990298 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.0 0.9 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.2 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.3 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.0 0.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.2 GO:0097255 R2TP complex(GO:0097255)
0.0 0.2 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.1 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.1 GO:0097179 NLRP1 inflammasome complex(GO:0072558) protease inhibitor complex(GO:0097179)
0.0 1.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.4 GO:0031143 pseudopodium(GO:0031143)
0.0 0.4 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.0 GO:0031523 Myb complex(GO:0031523)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.0 GO:0000229 cytoplasmic chromosome(GO:0000229)
0.0 0.2 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.1 GO:0097136 Bcl-2 family protein complex(GO:0097136)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 GO:0045569 TRAIL binding(GO:0045569)
0.2 0.6 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.2 0.9 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.2 0.5 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.4 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.1 1.5 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.4 GO:0016499 orexin receptor activity(GO:0016499)
0.1 0.4 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.1 0.4 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.1 0.7 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.1 0.3 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 1.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 0.2 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.1 0.2 GO:0098808 mRNA cap binding(GO:0098808)
0.1 0.2 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 0.7 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.2 GO:0002046 opsin binding(GO:0002046)
0.0 0.1 GO:0017129 triglyceride binding(GO:0017129)
0.0 0.1 GO:0052895 norspermine:oxygen oxidoreductase activity(GO:0052894) N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity(GO:0052895)
0.0 0.5 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.2 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.1 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.2 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.3 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.3 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.1 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 0.2 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.1 GO:0008480 sarcosine dehydrogenase activity(GO:0008480)
0.0 0.2 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.3 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.3 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.2 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.2 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.3 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.1 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.1 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 0.1 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.3 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.2 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 4.0 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.5 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 2.0 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.5 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 1.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.6 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.2 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.2 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.5 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.6 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis