Inflammatory response time course, HUVEC (Wada et al., 2009)
Name | miRBASE accession |
---|---|
hsa-miR-155-5p
|
MIMAT0000646 |
Promoter | Log-likelihood | Transcript | Gene | Gene Info |
---|---|---|---|---|
chr1_+_61547894 | 1.63 |
ENST00000403491.3
|
NFIA
|
nuclear factor I/A |
chr20_-_39317868 | 1.30 |
ENST00000373313.2
|
MAFB
|
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
chr9_-_14314066 | 1.05 |
ENST00000397575.3
|
NFIB
|
nuclear factor I/B |
chr6_+_15246501 | 1.02 |
ENST00000341776.2
|
JARID2
|
jumonji, AT rich interactive domain 2 |
chr10_+_8096631 | 0.85 |
ENST00000379328.3
|
GATA3
|
GATA binding protein 3 |
chr1_+_114522049 | 0.81 |
ENST00000369551.1
ENST00000320334.4 |
OLFML3
|
olfactomedin-like 3 |
chr14_-_30396948 | 0.75 |
ENST00000331968.5
|
PRKD1
|
protein kinase D1 |
chr2_+_28615669 | 0.71 |
ENST00000379619.1
ENST00000264716.4 |
FOSL2
|
FOS-like antigen 2 |
chr4_-_149365827 | 0.69 |
ENST00000344721.4
|
NR3C2
|
nuclear receptor subfamily 3, group C, member 2 |
chr14_-_91526922 | 0.64 |
ENST00000418736.2
ENST00000261991.3 |
RPS6KA5
|
ribosomal protein S6 kinase, 90kDa, polypeptide 5 |
chr12_+_20522179 | 0.60 |
ENST00000359062.3
|
PDE3A
|
phosphodiesterase 3A, cGMP-inhibited |
chr10_-_131762105 | 0.60 |
ENST00000368648.3
ENST00000355311.5 |
EBF3
|
early B-cell factor 3 |
chr9_+_5450503 | 0.60 |
ENST00000381573.4
ENST00000381577.3 |
CD274
|
CD274 molecule |
chr15_+_67813406 | 0.59 |
ENST00000342683.4
|
C15orf61
|
chromosome 15 open reading frame 61 |
chr2_+_173600671 | 0.58 |
ENST00000409036.1
|
RAPGEF4
|
Rap guanine nucleotide exchange factor (GEF) 4 |
chr2_+_46524537 | 0.58 |
ENST00000263734.3
|
EPAS1
|
endothelial PAS domain protein 1 |
chr1_+_63833261 | 0.53 |
ENST00000371108.4
|
ALG6
|
ALG6, alpha-1,3-glucosyltransferase |
chr19_-_31840438 | 0.51 |
ENST00000240587.4
|
TSHZ3
|
teashirt zinc finger homeobox 3 |
chrX_+_107069063 | 0.50 |
ENST00000262843.6
|
MID2
|
midline 2 |
chr19_+_1249869 | 0.49 |
ENST00000591446.2
|
MIDN
|
midnolin |
chr8_-_81083731 | 0.49 |
ENST00000379096.5
|
TPD52
|
tumor protein D52 |
chr16_-_10674528 | 0.47 |
ENST00000359543.3
|
EMP2
|
epithelial membrane protein 2 |
chr15_+_96873921 | 0.47 |
ENST00000394166.3
|
NR2F2
|
nuclear receptor subfamily 2, group F, member 2 |
chr4_+_145567173 | 0.46 |
ENST00000296575.3
|
HHIP
|
hedgehog interacting protein |
chr2_+_148778570 | 0.44 |
ENST00000407073.1
|
MBD5
|
methyl-CpG binding domain protein 5 |
chr12_+_72233487 | 0.43 |
ENST00000482439.2
ENST00000550746.1 ENST00000491063.1 ENST00000319106.8 ENST00000485960.2 ENST00000393309.3 |
TBC1D15
|
TBC1 domain family, member 15 |
chr12_+_96588143 | 0.42 |
ENST00000228741.3
ENST00000547249.1 |
ELK3
|
ELK3, ETS-domain protein (SRF accessory protein 2) |
chr2_-_43453734 | 0.36 |
ENST00000282388.3
|
ZFP36L2
|
ZFP36 ring finger protein-like 2 |
chr18_-_53255766 | 0.36 |
ENST00000566286.1
ENST00000564999.1 ENST00000566279.1 ENST00000354452.3 ENST00000356073.4 |
TCF4
|
transcription factor 4 |
chr7_+_95401851 | 0.33 |
ENST00000447467.2
|
DYNC1I1
|
dynein, cytoplasmic 1, intermediate chain 1 |
chr3_-_141868357 | 0.33 |
ENST00000489671.1
ENST00000475734.1 ENST00000467072.1 ENST00000499676.2 |
TFDP2
|
transcription factor Dp-2 (E2F dimerization partner 2) |
chr4_+_123747834 | 0.32 |
ENST00000264498.3
|
FGF2
|
fibroblast growth factor 2 (basic) |
chr10_+_18948311 | 0.31 |
ENST00000377275.3
|
ARL5B
|
ADP-ribosylation factor-like 5B |
chr9_-_16870704 | 0.30 |
ENST00000380672.4
ENST00000380667.2 ENST00000380666.2 ENST00000486514.1 |
BNC2
|
basonuclin 2 |
chr5_-_148930960 | 0.29 |
ENST00000261798.5
ENST00000377843.2 |
CSNK1A1
|
casein kinase 1, alpha 1 |
chr1_-_204121013 | 0.29 |
ENST00000367201.3
|
ETNK2
|
ethanolamine kinase 2 |
chr6_-_134373732 | 0.29 |
ENST00000275230.5
|
SLC2A12
|
solute carrier family 2 (facilitated glucose transporter), member 12 |
chr11_+_47279504 | 0.26 |
ENST00000441012.2
ENST00000437276.1 ENST00000436029.1 ENST00000467728.1 ENST00000405853.3 |
NR1H3
|
nuclear receptor subfamily 1, group H, member 3 |
chr11_-_73309228 | 0.26 |
ENST00000356467.4
ENST00000064778.4 |
FAM168A
|
family with sequence similarity 168, member A |
chr3_-_18466787 | 0.26 |
ENST00000338745.6
ENST00000450898.1 |
SATB1
|
SATB homeobox 1 |
chr9_+_35749203 | 0.26 |
ENST00000456972.2
ENST00000378078.4 |
RGP1
|
RGP1 retrograde golgi transport homolog (S. cerevisiae) |
chr12_-_15038779 | 0.26 |
ENST00000228938.5
ENST00000539261.1 |
MGP
|
matrix Gla protein |
chr1_+_66999799 | 0.25 |
ENST00000371035.3
ENST00000371036.3 ENST00000371037.4 |
SGIP1
|
SH3-domain GRB2-like (endophilin) interacting protein 1 |
chr1_-_234745234 | 0.25 |
ENST00000366610.3
ENST00000366609.3 |
IRF2BP2
|
interferon regulatory factor 2 binding protein 2 |
chr7_+_94139105 | 0.24 |
ENST00000297273.4
|
CASD1
|
CAS1 domain containing 1 |
chr7_+_106809406 | 0.24 |
ENST00000468410.1
ENST00000478930.1 ENST00000464009.1 ENST00000222574.4 |
HBP1
|
HMG-box transcription factor 1 |
chr3_+_32147997 | 0.22 |
ENST00000282541.5
|
GPD1L
|
glycerol-3-phosphate dehydrogenase 1-like |
chr17_-_49337392 | 0.22 |
ENST00000376381.2
ENST00000586178.1 |
MBTD1
|
mbt domain containing 1 |
chr12_-_25102252 | 0.21 |
ENST00000261192.7
|
BCAT1
|
branched chain amino-acid transaminase 1, cytosolic |
chr11_-_94964354 | 0.21 |
ENST00000536441.1
|
SESN3
|
sestrin 3 |
chr11_-_82782861 | 0.21 |
ENST00000524635.1
ENST00000526205.1 ENST00000527633.1 ENST00000533486.1 ENST00000533276.2 |
RAB30
|
RAB30, member RAS oncogene family |
chr1_-_22109682 | 0.20 |
ENST00000400301.1
ENST00000532737.1 |
USP48
|
ubiquitin specific peptidase 48 |
chr9_+_82186872 | 0.20 |
ENST00000376544.3
ENST00000376520.4 |
TLE4
|
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) |
chrX_-_150067173 | 0.20 |
ENST00000370377.3
ENST00000320893.6 |
CD99L2
|
CD99 molecule-like 2 |
chr14_+_103058948 | 0.19 |
ENST00000262241.6
|
RCOR1
|
REST corepressor 1 |
chr19_-_14629224 | 0.19 |
ENST00000254322.2
|
DNAJB1
|
DnaJ (Hsp40) homolog, subfamily B, member 1 |
chr1_-_1624083 | 0.19 |
ENST00000378662.1
ENST00000234800.6 |
SLC35E2B
|
solute carrier family 35, member E2B |
chr15_-_82338460 | 0.19 |
ENST00000558133.1
ENST00000329713.4 |
MEX3B
|
mex-3 RNA binding family member B |
chr1_+_215740709 | 0.18 |
ENST00000259154.4
|
KCTD3
|
potassium channel tetramerization domain containing 3 |
chr20_+_11871371 | 0.18 |
ENST00000254977.3
|
BTBD3
|
BTB (POZ) domain containing 3 |
chr2_+_70056762 | 0.18 |
ENST00000282570.3
|
GMCL1
|
germ cell-less, spermatogenesis associated 1 |
chr14_-_39901618 | 0.18 |
ENST00000554932.1
ENST00000298097.7 |
FBXO33
|
F-box protein 33 |
chr12_+_93771659 | 0.18 |
ENST00000337179.5
ENST00000415493.2 |
NUDT4
|
nudix (nucleoside diphosphate linked moiety X)-type motif 4 |
chr7_+_128864848 | 0.18 |
ENST00000325006.3
ENST00000446544.2 |
AHCYL2
|
adenosylhomocysteinase-like 2 |
chr17_-_19771216 | 0.16 |
ENST00000395544.4
|
ULK2
|
unc-51 like autophagy activating kinase 2 |
chr1_+_2160134 | 0.16 |
ENST00000378536.4
|
SKI
|
v-ski avian sarcoma viral oncogene homolog |
chr9_+_117350009 | 0.16 |
ENST00000374050.3
|
ATP6V1G1
|
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 |
chr11_+_113930291 | 0.15 |
ENST00000335953.4
|
ZBTB16
|
zinc finger and BTB domain containing 16 |
chr5_-_107717058 | 0.15 |
ENST00000359660.5
|
FBXL17
|
F-box and leucine-rich repeat protein 17 |
chr1_+_154377669 | 0.15 |
ENST00000368485.3
ENST00000344086.4 |
IL6R
|
interleukin 6 receptor |
chr21_+_30671189 | 0.15 |
ENST00000286800.3
|
BACH1
|
BTB and CNC homology 1, basic leucine zipper transcription factor 1 |
chr7_-_32931387 | 0.14 |
ENST00000304056.4
|
KBTBD2
|
kelch repeat and BTB (POZ) domain containing 2 |
chr7_-_130080977 | 0.13 |
ENST00000223208.5
|
CEP41
|
centrosomal protein 41kDa |
chr17_+_35849937 | 0.13 |
ENST00000394389.4
|
DUSP14
|
dual specificity phosphatase 14 |
chr11_-_64901978 | 0.13 |
ENST00000294256.8
ENST00000377190.3 |
SYVN1
|
synovial apoptosis inhibitor 1, synoviolin |
chr16_-_8962200 | 0.13 |
ENST00000562843.1
ENST00000561530.1 ENST00000396593.2 |
CARHSP1
|
calcium regulated heat stable protein 1, 24kDa |
chr11_+_57308979 | 0.12 |
ENST00000457912.1
|
SMTNL1
|
smoothelin-like 1 |
chr2_+_208394616 | 0.12 |
ENST00000432329.2
ENST00000353267.3 ENST00000445803.1 |
CREB1
|
cAMP responsive element binding protein 1 |
chr1_+_214161272 | 0.12 |
ENST00000498508.2
ENST00000366958.4 |
PROX1
|
prospero homeobox 1 |
chr15_+_77223960 | 0.12 |
ENST00000394885.3
|
RCN2
|
reticulocalbin 2, EF-hand calcium binding domain |
chr5_+_172483347 | 0.12 |
ENST00000522692.1
ENST00000296953.2 ENST00000540014.1 ENST00000520420.1 |
CREBRF
|
CREB3 regulatory factor |
chr17_-_40306934 | 0.11 |
ENST00000592574.1
ENST00000550406.1 ENST00000547517.1 ENST00000393860.3 ENST00000346213.4 |
CTD-2132N18.3
RAB5C
|
Uncharacterized protein RAB5C, member RAS oncogene family |
chr17_-_65241281 | 0.11 |
ENST00000358691.5
ENST00000580168.1 |
HELZ
|
helicase with zinc finger |
chr16_-_11350036 | 0.11 |
ENST00000332029.2
|
SOCS1
|
suppressor of cytokine signaling 1 |
chr9_+_91003271 | 0.10 |
ENST00000375859.3
ENST00000541629.1 |
SPIN1
|
spindlin 1 |
chr14_-_34931458 | 0.10 |
ENST00000298130.4
|
SPTSSA
|
serine palmitoyltransferase, small subunit A |
chr13_-_29069232 | 0.10 |
ENST00000282397.4
ENST00000541932.1 ENST00000539099.1 |
FLT1
|
fms-related tyrosine kinase 1 |
chr1_-_70671216 | 0.10 |
ENST00000370952.3
|
LRRC40
|
leucine rich repeat containing 40 |
chr1_-_91487013 | 0.10 |
ENST00000347275.5
ENST00000370440.1 |
ZNF644
|
zinc finger protein 644 |
chr10_-_91403625 | 0.10 |
ENST00000322191.6
ENST00000342512.3 ENST00000371774.2 |
PANK1
|
pantothenate kinase 1 |
chr8_-_95961578 | 0.09 |
ENST00000448464.2
ENST00000342697.4 |
TP53INP1
|
tumor protein p53 inducible nuclear protein 1 |
chr14_+_31028329 | 0.09 |
ENST00000206595.6
|
G2E3
|
G2/M-phase specific E3 ubiquitin protein ligase |
chr2_-_208634287 | 0.09 |
ENST00000295417.3
|
FZD5
|
frizzled family receptor 5 |
chr14_+_75745477 | 0.09 |
ENST00000303562.4
ENST00000554617.1 ENST00000554212.1 ENST00000535987.1 ENST00000555242.1 |
FOS
|
FBJ murine osteosarcoma viral oncogene homolog |
chr2_+_120517174 | 0.09 |
ENST00000263708.2
|
PTPN4
|
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) |
chr2_+_48010221 | 0.09 |
ENST00000234420.5
|
MSH6
|
mutS homolog 6 |
chr12_+_5019061 | 0.09 |
ENST00000382545.3
|
KCNA1
|
potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) |
chr6_+_36853607 | 0.09 |
ENST00000480824.2
ENST00000355190.3 ENST00000373685.1 |
C6orf89
|
chromosome 6 open reading frame 89 |
chr5_+_112043186 | 0.08 |
ENST00000509732.1
ENST00000457016.1 ENST00000507379.1 |
APC
|
adenomatous polyposis coli |
chr8_-_66754172 | 0.08 |
ENST00000401827.3
|
PDE7A
|
phosphodiesterase 7A |
chr17_-_13505219 | 0.08 |
ENST00000284110.1
|
HS3ST3A1
|
heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
chr4_-_148605265 | 0.08 |
ENST00000541232.1
ENST00000322396.6 |
PRMT10
|
protein arginine methyltransferase 10 (putative) |
chr11_+_34642656 | 0.08 |
ENST00000257831.3
ENST00000450654.2 |
EHF
|
ets homologous factor |
chr2_-_64371546 | 0.08 |
ENST00000358912.4
|
PELI1
|
pellino E3 ubiquitin protein ligase 1 |
chr6_-_2751146 | 0.08 |
ENST00000268446.5
ENST00000274643.7 |
MYLK4
|
myosin light chain kinase family, member 4 |
chr10_+_72238517 | 0.08 |
ENST00000263563.6
|
PALD1
|
phosphatase domain containing, paladin 1 |
chr20_+_37554955 | 0.08 |
ENST00000217429.4
|
FAM83D
|
family with sequence similarity 83, member D |
chr8_+_37553261 | 0.08 |
ENST00000331569.4
|
ZNF703
|
zinc finger protein 703 |
chr10_+_180987 | 0.08 |
ENST00000381591.1
|
ZMYND11
|
zinc finger, MYND-type containing 11 |
chr10_+_69644404 | 0.07 |
ENST00000212015.6
|
SIRT1
|
sirtuin 1 |
chr5_-_39074479 | 0.07 |
ENST00000514735.1
ENST00000296782.5 ENST00000357387.3 |
RICTOR
|
RPTOR independent companion of MTOR, complex 2 |
chr20_+_31595406 | 0.07 |
ENST00000170150.3
|
BPIFB2
|
BPI fold containing family B, member 2 |
chrX_-_20284958 | 0.07 |
ENST00000379565.3
|
RPS6KA3
|
ribosomal protein S6 kinase, 90kDa, polypeptide 3 |
chr21_-_40685477 | 0.07 |
ENST00000342449.3
|
BRWD1
|
bromodomain and WD repeat domain containing 1 |
chr12_-_57400227 | 0.07 |
ENST00000300101.2
|
ZBTB39
|
zinc finger and BTB domain containing 39 |
chr21_-_34144157 | 0.07 |
ENST00000331923.4
|
PAXBP1
|
PAX3 and PAX7 binding protein 1 |
chr5_+_102201430 | 0.06 |
ENST00000438793.3
ENST00000346918.2 |
PAM
|
peptidylglycine alpha-amidating monooxygenase |
chr5_+_153418466 | 0.06 |
ENST00000522782.1
ENST00000439768.2 ENST00000436816.1 ENST00000322602.5 ENST00000522177.1 ENST00000520899.1 |
MFAP3
|
microfibrillar-associated protein 3 |
chr9_-_132597529 | 0.06 |
ENST00000372447.3
|
C9orf78
|
chromosome 9 open reading frame 78 |
chr10_-_119806085 | 0.06 |
ENST00000355624.3
|
RAB11FIP2
|
RAB11 family interacting protein 2 (class I) |
chr17_+_55333876 | 0.06 |
ENST00000284073.2
|
MSI2
|
musashi RNA-binding protein 2 |
chr14_-_54908043 | 0.06 |
ENST00000556113.1
ENST00000553660.1 ENST00000395573.4 ENST00000557690.1 ENST00000216416.4 |
CNIH1
|
cornichon family AMPA receptor auxiliary protein 1 |
chr1_-_46216286 | 0.06 |
ENST00000396478.3
ENST00000359942.4 |
IPP
|
intracisternal A particle-promoted polypeptide |
chr16_+_69599861 | 0.06 |
ENST00000354436.2
|
NFAT5
|
nuclear factor of activated T-cells 5, tonicity-responsive |
chr19_+_34663397 | 0.05 |
ENST00000540746.2
ENST00000544216.3 ENST00000433627.5 |
LSM14A
|
LSM14A, SCD6 homolog A (S. cerevisiae) |
chr1_-_235292250 | 0.05 |
ENST00000366607.4
|
TOMM20
|
translocase of outer mitochondrial membrane 20 homolog (yeast) |
chr5_+_110559784 | 0.05 |
ENST00000282356.4
|
CAMK4
|
calcium/calmodulin-dependent protein kinase IV |
chr17_-_62207485 | 0.05 |
ENST00000433197.3
|
ERN1
|
endoplasmic reticulum to nucleus signaling 1 |
chr10_-_13390270 | 0.05 |
ENST00000378614.4
ENST00000545675.1 ENST00000327347.5 |
SEPHS1
|
selenophosphate synthetase 1 |
chr15_+_38544476 | 0.05 |
ENST00000299084.4
|
SPRED1
|
sprouty-related, EVH1 domain containing 1 |
chr15_-_34628951 | 0.05 |
ENST00000397707.2
ENST00000560611.1 |
SLC12A6
|
solute carrier family 12 (potassium/chloride transporter), member 6 |
chr16_+_53088885 | 0.05 |
ENST00000566029.1
ENST00000447540.1 |
CHD9
|
chromodomain helicase DNA binding protein 9 |
chr3_+_178866199 | 0.05 |
ENST00000263967.3
|
PIK3CA
|
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha |
chr12_-_54582655 | 0.05 |
ENST00000504338.1
ENST00000514685.1 ENST00000504797.1 ENST00000513838.1 ENST00000505128.1 ENST00000337581.3 ENST00000503306.1 ENST00000243112.5 ENST00000514196.1 ENST00000506169.1 ENST00000507904.1 ENST00000508394.2 |
SMUG1
|
single-strand-selective monofunctional uracil-DNA glycosylase 1 |
chr3_+_49726932 | 0.05 |
ENST00000327697.6
ENST00000432042.1 ENST00000454491.1 |
RNF123
|
ring finger protein 123 |
chrX_+_16964794 | 0.05 |
ENST00000357277.3
|
REPS2
|
RALBP1 associated Eps domain containing 2 |
chr18_+_67956135 | 0.05 |
ENST00000397942.3
|
SOCS6
|
suppressor of cytokine signaling 6 |
chr17_+_4613918 | 0.05 |
ENST00000574954.1
ENST00000346341.2 ENST00000572457.1 ENST00000381488.6 ENST00000412477.3 ENST00000571428.1 ENST00000575877.1 |
ARRB2
|
arrestin, beta 2 |
chr2_-_200322723 | 0.04 |
ENST00000417098.1
|
SATB2
|
SATB homeobox 2 |
chr6_-_107780751 | 0.04 |
ENST00000453874.2
ENST00000369037.4 ENST00000369031.4 |
PDSS2
|
prenyl (decaprenyl) diphosphate synthase, subunit 2 |
chr1_-_153895377 | 0.04 |
ENST00000368655.4
|
GATAD2B
|
GATA zinc finger domain containing 2B |
chr10_-_98346801 | 0.04 |
ENST00000371142.4
|
TM9SF3
|
transmembrane 9 superfamily member 3 |
chr6_+_71122974 | 0.04 |
ENST00000418814.2
|
FAM135A
|
family with sequence similarity 135, member A |
chr5_+_54603566 | 0.04 |
ENST00000230640.5
|
SKIV2L2
|
superkiller viralicidic activity 2-like 2 (S. cerevisiae) |
chr12_+_51442101 | 0.04 |
ENST00000550929.1
ENST00000262055.4 ENST00000550442.1 ENST00000549340.1 ENST00000548209.1 ENST00000548251.1 ENST00000550814.1 ENST00000547660.1 ENST00000380123.2 ENST00000548401.1 ENST00000418425.2 ENST00000547008.1 ENST00000552739.1 |
LETMD1
|
LETM1 domain containing 1 |
chr19_-_1605424 | 0.04 |
ENST00000589880.1
ENST00000585671.1 ENST00000591899.3 |
UQCR11
|
ubiquinol-cytochrome c reductase, complex III subunit XI |
chr16_-_20911641 | 0.04 |
ENST00000564349.1
ENST00000324344.4 |
ERI2
DCUN1D3
|
ERI1 exoribonuclease family member 2 DCN1, defective in cullin neddylation 1, domain containing 3 |
chr12_-_123011536 | 0.03 |
ENST00000331738.7
ENST00000354654.2 |
RSRC2
|
arginine/serine-rich coiled-coil 2 |
chr1_+_244214577 | 0.03 |
ENST00000358704.4
|
ZBTB18
|
zinc finger and BTB domain containing 18 |
chr15_-_61521495 | 0.03 |
ENST00000335670.6
|
RORA
|
RAR-related orphan receptor A |
chr10_-_120101804 | 0.03 |
ENST00000369183.4
ENST00000369172.4 |
FAM204A
|
family with sequence similarity 204, member A |
chr2_+_46926048 | 0.03 |
ENST00000306503.5
|
SOCS5
|
suppressor of cytokine signaling 5 |
chr7_+_138916231 | 0.03 |
ENST00000473989.3
ENST00000288561.8 |
UBN2
|
ubinuclein 2 |
chr13_+_20532807 | 0.03 |
ENST00000382869.3
ENST00000382881.3 |
ZMYM2
|
zinc finger, MYM-type 2 |
chr10_+_104263743 | 0.03 |
ENST00000369902.3
ENST00000369899.2 ENST00000423559.2 |
SUFU
|
suppressor of fused homolog (Drosophila) |
chr10_+_114206956 | 0.03 |
ENST00000432306.1
ENST00000393077.2 |
VTI1A
|
vesicle transport through interaction with t-SNAREs 1A |
chr1_+_53527854 | 0.03 |
ENST00000371500.3
ENST00000395871.2 ENST00000312553.5 |
PODN
|
podocan |
chr4_-_10458982 | 0.03 |
ENST00000326756.3
|
ZNF518B
|
zinc finger protein 518B |
chrX_-_153979315 | 0.03 |
ENST00000369575.3
ENST00000369568.4 ENST00000424127.2 |
GAB3
|
GRB2-associated binding protein 3 |
chr7_-_14029515 | 0.02 |
ENST00000430479.1
ENST00000405218.2 ENST00000343495.5 |
ETV1
|
ets variant 1 |
chr11_+_119076745 | 0.02 |
ENST00000264033.4
|
CBL
|
Cbl proto-oncogene, E3 ubiquitin protein ligase |
chr18_-_5895954 | 0.02 |
ENST00000581347.2
|
TMEM200C
|
transmembrane protein 200C |
chr6_+_135502466 | 0.02 |
ENST00000367814.4
|
MYB
|
v-myb avian myeloblastosis viral oncogene homolog |
chr12_+_110338063 | 0.02 |
ENST00000405876.4
|
TCHP
|
trichoplein, keratin filament binding |
chr8_+_73921085 | 0.02 |
ENST00000276603.5
ENST00000276602.6 ENST00000518874.1 |
TERF1
|
telomeric repeat binding factor (NIMA-interacting) 1 |
chr17_-_1303462 | 0.02 |
ENST00000573026.1
ENST00000575977.1 ENST00000571732.1 ENST00000264335.8 |
YWHAE
|
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon |
chr2_-_101925055 | 0.02 |
ENST00000295317.3
|
RNF149
|
ring finger protein 149 |
chr4_-_16228120 | 0.02 |
ENST00000405303.2
|
TAPT1
|
transmembrane anterior posterior transformation 1 |
chr8_-_57123815 | 0.02 |
ENST00000316981.3
ENST00000423799.2 ENST00000429357.2 |
PLAG1
|
pleiomorphic adenoma gene 1 |
chr22_-_50217981 | 0.02 |
ENST00000457780.2
|
BRD1
|
bromodomain containing 1 |
chr5_+_112312416 | 0.02 |
ENST00000389063.2
|
DCP2
|
decapping mRNA 2 |
chr19_+_4402659 | 0.02 |
ENST00000301280.5
ENST00000585854.1 |
CHAF1A
|
chromatin assembly factor 1, subunit A (p150) |
chrX_-_13956737 | 0.01 |
ENST00000454189.2
|
GPM6B
|
glycoprotein M6B |
chr15_+_50716576 | 0.01 |
ENST00000560297.1
ENST00000307179.4 ENST00000396444.3 ENST00000433963.1 ENST00000425032.3 |
USP8
|
ubiquitin specific peptidase 8 |
chr2_-_166930131 | 0.01 |
ENST00000303395.4
ENST00000409050.1 ENST00000423058.2 ENST00000375405.3 |
SCN1A
|
sodium channel, voltage-gated, type I, alpha subunit |
chr7_-_35293740 | 0.01 |
ENST00000408931.3
|
TBX20
|
T-box 20 |
chr5_+_141488070 | 0.01 |
ENST00000253814.4
|
NDFIP1
|
Nedd4 family interacting protein 1 |
chr8_+_40010989 | 0.01 |
ENST00000315792.3
|
C8orf4
|
chromosome 8 open reading frame 4 |
chr7_-_113559104 | 0.01 |
ENST00000284601.3
|
PPP1R3A
|
protein phosphatase 1, regulatory subunit 3A |
chr14_-_21905395 | 0.01 |
ENST00000430710.3
ENST00000553283.1 |
CHD8
|
chromodomain helicase DNA binding protein 8 |
chr4_-_88141755 | 0.01 |
ENST00000273963.5
|
KLHL8
|
kelch-like family member 8 |
chr10_+_12171721 | 0.01 |
ENST00000379020.4
ENST00000379017.3 |
SEC61A2
|
Sec61 alpha 2 subunit (S. cerevisiae) |
chr1_+_89149905 | 0.01 |
ENST00000316005.7
ENST00000370521.3 ENST00000370505.3 |
PKN2
|
protein kinase N2 |
chr1_+_36396677 | 0.01 |
ENST00000373191.4
ENST00000397828.2 |
AGO3
|
argonaute RISC catalytic component 3 |
chr12_+_862089 | 0.01 |
ENST00000315939.6
ENST00000537687.1 ENST00000447667.2 |
WNK1
|
WNK lysine deficient protein kinase 1 |
chr10_+_114709999 | 0.01 |
ENST00000355995.4
ENST00000545257.1 ENST00000543371.1 ENST00000536810.1 ENST00000355717.4 ENST00000538897.1 ENST00000534894.1 |
TCF7L2
|
transcription factor 7-like 2 (T-cell specific, HMG-box) |
chr4_+_95129061 | 0.01 |
ENST00000354268.4
|
SMARCAD1
|
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 |
chr8_-_65711310 | 0.01 |
ENST00000310193.3
|
CYP7B1
|
cytochrome P450, family 7, subfamily B, polypeptide 1 |
chr2_-_69870835 | 0.01 |
ENST00000409085.4
ENST00000406297.3 |
AAK1
|
AP2 associated kinase 1 |
chr8_+_67579807 | 0.01 |
ENST00000519289.1
ENST00000519561.1 ENST00000521889.1 |
C8orf44-SGK3
C8orf44
|
C8orf44-SGK3 readthrough chromosome 8 open reading frame 44 |
chr1_+_101702417 | 0.01 |
ENST00000305352.6
|
S1PR1
|
sphingosine-1-phosphate receptor 1 |
chr1_+_33283043 | 0.00 |
ENST00000373476.1
ENST00000373475.5 ENST00000529027.1 ENST00000398243.3 |
S100PBP
|
S100P binding protein |
chr6_-_80247105 | 0.00 |
ENST00000369846.4
|
LCA5
|
Leber congenital amaurosis 5 |
chr1_+_36273743 | 0.00 |
ENST00000373210.3
|
AGO4
|
argonaute RISC catalytic component 4 |
chr19_+_11485333 | 0.00 |
ENST00000312423.2
|
SWSAP1
|
SWIM-type zinc finger 7 associated protein 1 |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 1.3 | GO:0035283 | rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284) |
0.2 | 0.8 | GO:0060995 | pro-T cell differentiation(GO:0002572) cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204) negative regulation of DNA demethylation(GO:1901536) |
0.2 | 1.1 | GO:2000795 | negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795) |
0.1 | 0.6 | GO:0043988 | histone H3-S28 phosphorylation(GO:0043988) |
0.1 | 0.5 | GO:0009956 | radial pattern formation(GO:0009956) |
0.1 | 0.6 | GO:0043129 | surfactant homeostasis(GO:0043129) |
0.1 | 0.7 | GO:0089700 | protein kinase D signaling(GO:0089700) |
0.1 | 0.6 | GO:0071321 | cellular response to cGMP(GO:0071321) |
0.1 | 0.3 | GO:0090341 | negative regulation of secretion of lysosomal enzymes(GO:0090341) |
0.1 | 0.6 | GO:2001181 | positive regulation of interleukin-10 secretion(GO:2001181) |
0.1 | 0.5 | GO:1903300 | negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300) |
0.1 | 0.4 | GO:0060399 | positive regulation of growth hormone receptor signaling pathway(GO:0060399) |
0.1 | 1.1 | GO:0051574 | positive regulation of histone H3-K9 methylation(GO:0051574) |
0.1 | 0.2 | GO:0090038 | negative regulation of protein kinase C signaling(GO:0090038) |
0.1 | 1.4 | GO:0072189 | ureter development(GO:0072189) |
0.1 | 0.2 | GO:0002384 | hepatic immune response(GO:0002384) |
0.0 | 0.1 | GO:0000117 | regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117) |
0.0 | 0.5 | GO:0070836 | caveola assembly(GO:0070836) |
0.0 | 0.3 | GO:1904849 | positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546) |
0.0 | 0.2 | GO:0031064 | negative regulation of histone deacetylation(GO:0031064) |
0.0 | 0.4 | GO:1904628 | response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628) |
0.0 | 0.1 | GO:0090425 | hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979) |
0.0 | 0.1 | GO:1900169 | regulation of glucocorticoid mediated signaling pathway(GO:1900169) |
0.0 | 0.3 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
0.0 | 0.5 | GO:0035372 | protein localization to microtubule(GO:0035372) |
0.0 | 0.2 | GO:0009099 | branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099) |
0.0 | 0.1 | GO:1904760 | myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760) |
0.0 | 0.2 | GO:0098728 | germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728) |
0.0 | 0.1 | GO:0060061 | Spemann organizer formation(GO:0060061) |
0.0 | 0.2 | GO:1901910 | diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911) |
0.0 | 0.7 | GO:0003334 | keratinocyte development(GO:0003334) |
0.0 | 0.1 | GO:1901727 | positive regulation of histone deacetylase activity(GO:1901727) |
0.0 | 0.2 | GO:1904885 | beta-catenin destruction complex assembly(GO:1904885) |
0.0 | 0.5 | GO:0002087 | regulation of respiratory gaseous exchange by neurological system process(GO:0002087) |
0.0 | 0.3 | GO:2000582 | positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582) |
0.0 | 0.2 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
0.0 | 0.0 | GO:2000653 | regulation of genetic imprinting(GO:2000653) |
0.0 | 0.5 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
0.0 | 0.1 | GO:0050976 | detection of mechanical stimulus involved in sensory perception of touch(GO:0050976) |
0.0 | 0.1 | GO:1904550 | chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550) |
0.0 | 0.2 | GO:0075071 | autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071) |
0.0 | 0.1 | GO:0030950 | establishment or maintenance of actin cytoskeleton polarity(GO:0030950) |
0.0 | 0.1 | GO:0016260 | selenocysteine biosynthetic process(GO:0016260) |
0.0 | 0.1 | GO:0018032 | protein amidation(GO:0018032) |
0.0 | 0.2 | GO:0038203 | TORC2 signaling(GO:0038203) negative regulation of TORC1 signaling(GO:1904262) |
0.0 | 0.3 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
0.0 | 0.2 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
0.0 | 0.1 | GO:0035927 | RNA import into mitochondrion(GO:0035927) |
0.0 | 0.1 | GO:0018095 | protein polyglutamylation(GO:0018095) |
0.0 | 0.2 | GO:0070933 | histone H4 deacetylation(GO:0070933) |
0.0 | 0.1 | GO:0000710 | meiotic mismatch repair(GO:0000710) |
0.0 | 0.5 | GO:0060441 | epithelial tube branching involved in lung morphogenesis(GO:0060441) |
0.0 | 0.3 | GO:0043586 | tongue development(GO:0043586) |
0.0 | 0.0 | GO:0097695 | establishment of RNA localization to telomere(GO:0097694) establishment of macromolecular complex localization to telomere(GO:0097695) |
0.0 | 0.1 | GO:0001661 | conditioned taste aversion(GO:0001661) |
0.0 | 0.3 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
0.0 | 0.1 | GO:0036289 | peptidyl-serine autophosphorylation(GO:0036289) |
0.0 | 0.1 | GO:0042539 | hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 1.1 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
0.0 | 0.2 | GO:0005896 | interleukin-6 receptor complex(GO:0005896) |
0.0 | 0.2 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
0.0 | 1.1 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
0.0 | 0.1 | GO:0000839 | Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839) |
0.0 | 0.1 | GO:0032301 | MutSalpha complex(GO:0032301) |
0.0 | 0.1 | GO:1990597 | AIP1-IRE1 complex(GO:1990597) |
0.0 | 0.1 | GO:1990589 | ATF4-CREB1 transcription factor complex(GO:1990589) |
0.0 | 0.3 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
0.0 | 0.4 | GO:0010369 | chromocenter(GO:0010369) |
0.0 | 0.7 | GO:0000421 | autophagosome membrane(GO:0000421) |
0.0 | 0.2 | GO:0061700 | GATOR2 complex(GO:0061700) |
0.0 | 0.1 | GO:0017059 | serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211) |
0.0 | 0.1 | GO:0035976 | AP1 complex(GO:0035976) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 0.6 | GO:0004119 | cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) |
0.1 | 0.4 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
0.1 | 0.8 | GO:0005134 | interleukin-2 receptor binding(GO:0005134) |
0.1 | 0.5 | GO:0097108 | hedgehog family protein binding(GO:0097108) |
0.1 | 0.2 | GO:0035033 | histone deacetylase regulator activity(GO:0035033) |
0.1 | 0.3 | GO:0032810 | sterol response element binding(GO:0032810) |
0.1 | 0.2 | GO:0004915 | interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981) |
0.0 | 0.2 | GO:0052654 | branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656) |
0.0 | 0.2 | GO:0052840 | endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848) |
0.0 | 0.3 | GO:0004305 | ethanolamine kinase activity(GO:0004305) |
0.0 | 0.2 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
0.0 | 0.8 | GO:0004697 | protein kinase C activity(GO:0004697) |
0.0 | 0.5 | GO:0046527 | glucosyltransferase activity(GO:0046527) |
0.0 | 0.4 | GO:0001087 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
0.0 | 1.0 | GO:0032452 | histone demethylase activity(GO:0032452) |
0.0 | 0.1 | GO:0032143 | single thymine insertion binding(GO:0032143) |
0.0 | 0.2 | GO:0016413 | O-acetyltransferase activity(GO:0016413) |
0.0 | 0.3 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
0.0 | 0.1 | GO:0004758 | serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454) |
0.0 | 0.1 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
0.0 | 0.3 | GO:0055056 | D-glucose transmembrane transporter activity(GO:0055056) |
0.0 | 0.1 | GO:0043398 | HLH domain binding(GO:0043398) |
0.0 | 0.4 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
0.0 | 0.1 | GO:0004756 | selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781) |
0.0 | 0.1 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
0.0 | 0.1 | GO:0004504 | peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598) |
0.0 | 0.1 | GO:1990763 | arrestin family protein binding(GO:1990763) |
0.0 | 0.0 | GO:0031859 | platelet activating factor receptor binding(GO:0031859) |
0.0 | 0.3 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
0.0 | 0.1 | GO:0050692 | DBD domain binding(GO:0050692) |
0.0 | 0.0 | GO:0000702 | oxidized base lesion DNA N-glycosylase activity(GO:0000702) |
0.0 | 0.1 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
0.0 | 0.5 | GO:0001972 | retinoic acid binding(GO:0001972) |
0.0 | 0.6 | GO:0030552 | cAMP binding(GO:0030552) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 0.8 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
0.0 | 2.4 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
0.0 | 0.8 | PID IL27 PATHWAY | IL27-mediated signaling events |
0.0 | 1.0 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
0.0 | 0.2 | ST STAT3 PATHWAY | STAT3 Pathway |
0.0 | 0.4 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
0.0 | 0.7 | ST GA13 PATHWAY | G alpha 13 Pathway |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 1.1 | REACTOME RNA POL III TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |
0.0 | 0.3 | REACTOME SIGNALING BY FGFR3 MUTANTS | Genes involved in Signaling by FGFR3 mutants |
0.0 | 0.6 | REACTOME PD1 SIGNALING | Genes involved in PD-1 signaling |
0.0 | 0.6 | REACTOME ERK MAPK TARGETS | Genes involved in ERK/MAPK targets |
0.0 | 0.5 | REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
0.0 | 0.4 | REACTOME CTNNB1 PHOSPHORYLATION CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
0.0 | 0.1 | REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION | Genes involved in Nuclear Events (kinase and transcription factor activation) |
0.0 | 0.6 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
0.0 | 0.3 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
0.0 | 0.3 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |
0.0 | 0.5 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
0.0 | 0.5 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
0.0 | 1.0 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |