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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for UCACAGU

Z-value: 0.42

Motif logo

miRNA associated with seed UCACAGU

NamemiRBASE accession
MIMAT0000084
MIMAT0000419

Activity profile of UCACAGU motif

Sorted Z-values of UCACAGU motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_131762105 0.93 ENST00000368648.3
ENST00000355311.5
early B-cell factor 3
chr8_-_22550815 0.90 ENST00000317216.2
early growth response 3
chr6_+_136172820 0.88 ENST00000308191.6
phosphodiesterase 7B
chr7_-_27183263 0.76 ENST00000222726.3
homeobox A5
chr9_-_134145880 0.67 ENST00000372269.3
ENST00000464831.1
family with sequence similarity 78, member A
chr2_+_7057523 0.60 ENST00000320892.6
ring finger protein 144A
chr7_-_27213893 0.58 ENST00000283921.4
homeobox A10
chr8_-_93115445 0.58 ENST00000523629.1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr1_-_92351769 0.55 ENST00000212355.4
transforming growth factor, beta receptor III
chr10_+_8096631 0.55 ENST00000379328.3
GATA binding protein 3
chr15_+_41221536 0.54 ENST00000249749.5
delta-like 4 (Drosophila)
chr3_+_58223228 0.53 ENST00000478253.1
ENST00000295962.4
abhydrolase domain containing 6
chr14_+_56585048 0.53 ENST00000267460.4
pellino E3 ubiquitin protein ligase family member 2
chr9_+_130830451 0.52 ENST00000373068.2
ENST00000373069.5
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr21_-_44846999 0.51 ENST00000270162.6
salt-inducible kinase 1
chr10_-_81205373 0.48 ENST00000372336.3
zinc finger, CCHC domain containing 24
chr1_+_221051699 0.45 ENST00000366903.6
H2.0-like homeobox
chr1_-_154474589 0.42 ENST00000304760.2
Src homology 2 domain containing E
chr3_+_20081515 0.42 ENST00000263754.4
K(lysine) acetyltransferase 2B
chr3_+_150126101 0.42 ENST00000361875.3
ENST00000361136.2
TSC22 domain family, member 2
chr9_-_140196703 0.41 ENST00000356628.2
NOTCH-regulated ankyrin repeat protein
chr3_-_39195037 0.41 ENST00000273153.5
cysteine-serine-rich nuclear protein 1
chr6_+_7107999 0.40 ENST00000491191.1
ENST00000379938.2
ENST00000471433.1
ras responsive element binding protein 1
chr22_-_28197486 0.40 ENST00000302326.4
meningioma (disrupted in balanced translocation) 1
chr19_-_17356697 0.40 ENST00000291442.3
nuclear receptor subfamily 2, group F, member 6
chr5_+_176560742 0.39 ENST00000439151.2
nuclear receptor binding SET domain protein 1
chr8_-_124553437 0.36 ENST00000517956.1
ENST00000443022.2
F-box protein 32
chr8_-_127570603 0.36 ENST00000304916.3
family with sequence similarity 84, member B
chr19_+_45973120 0.35 ENST00000592811.1
ENST00000586615.1
FBJ murine osteosarcoma viral oncogene homolog B
chr22_+_51112800 0.33 ENST00000414786.2
SH3 and multiple ankyrin repeat domains 3
chr9_-_14314066 0.32 ENST00000397575.3
nuclear factor I/B
chr6_+_30524663 0.32 ENST00000376560.3
proline rich 3
chr10_+_112257596 0.32 ENST00000369583.3
dual specificity phosphatase 5
chr3_-_128212016 0.32 ENST00000498200.1
ENST00000341105.2
GATA binding protein 2
chr8_+_120220561 0.30 ENST00000276681.6
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr10_-_102279586 0.30 ENST00000370345.3
ENST00000451524.1
ENST00000370329.5
SEC31 homolog B (S. cerevisiae)
chr2_-_43453734 0.30 ENST00000282388.3
ZFP36 ring finger protein-like 2
chr6_+_161412759 0.30 ENST00000366919.2
ENST00000392142.4
ENST00000366920.2
ENST00000348824.7
mitogen-activated protein kinase kinase kinase 4
chr1_+_61547894 0.30 ENST00000403491.3
nuclear factor I/A
chr2_-_166651191 0.29 ENST00000392701.3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr5_+_52285144 0.29 ENST00000296585.5
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
chr1_+_116184566 0.28 ENST00000355485.2
ENST00000369510.4
VANGL planar cell polarity protein 1
chr1_+_76540386 0.28 ENST00000328299.3
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr12_+_20522179 0.28 ENST00000359062.3
phosphodiesterase 3A, cGMP-inhibited
chr3_-_129407535 0.28 ENST00000432054.2
transmembrane and coiled-coil domain family 1
chr1_+_206557366 0.28 ENST00000414007.1
ENST00000419187.2
SLIT-ROBO Rho GTPase activating protein 2
chr2_+_148778570 0.28 ENST00000407073.1
methyl-CpG binding domain protein 5
chr19_+_1249869 0.27 ENST00000591446.2
midnolin
chr14_+_61788429 0.27 ENST00000332981.5
protein kinase C, eta
chr5_-_31532160 0.26 ENST00000511367.2
ENST00000513349.1
drosha, ribonuclease type III
chr8_-_28243934 0.25 ENST00000521185.1
ENST00000520290.1
ENST00000344423.5
zinc finger protein 395
chr1_+_203274639 0.24 ENST00000290551.4
BTG family, member 2
chr13_+_33160553 0.24 ENST00000315596.10
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr4_+_26862400 0.23 ENST00000467011.1
ENST00000412829.2
stromal interaction molecule 2
chrX_-_110655391 0.23 ENST00000356915.2
ENST00000356220.3
doublecortin
chr19_-_36391434 0.23 ENST00000396901.1
ENST00000585925.1
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
chr16_+_577697 0.23 ENST00000562370.1
ENST00000568988.1
ENST00000219611.2
calpain 15
chr10_+_70320413 0.23 ENST00000373644.4
tet methylcytosine dioxygenase 1
chr3_-_124774802 0.23 ENST00000311127.4
heart development protein with EGF-like domains 1
chr19_+_32896697 0.23 ENST00000586987.1
dpy-19-like 3 (C. elegans)
chr4_+_144257915 0.22 ENST00000262995.4
GRB2-associated binding protein 1
chr10_-_52383644 0.22 ENST00000361781.2
sphingomyelin synthase 1
chr14_+_100259666 0.22 ENST00000262233.6
ENST00000334192.4
echinoderm microtubule associated protein like 1
chr10_-_119806085 0.21 ENST00000355624.3
RAB11 family interacting protein 2 (class I)
chr17_-_80056099 0.21 ENST00000306749.2
fatty acid synthase
chr7_+_77325738 0.21 ENST00000334955.8
round spermatid basic protein 1-like
chr8_-_57123815 0.21 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
pleiomorphic adenoma gene 1
chr9_-_127905736 0.21 ENST00000336505.6
ENST00000373549.4
suppressor of cancer cell invasion
chr9_-_126030817 0.20 ENST00000348403.5
ENST00000447404.2
ENST00000360998.3
spermatid perinuclear RNA binding protein
chr12_-_42538657 0.20 ENST00000398675.3
glucoside xylosyltransferase 1
chr5_+_74632993 0.20 ENST00000287936.4
3-hydroxy-3-methylglutaryl-CoA reductase
chr17_-_35969409 0.20 ENST00000394378.2
ENST00000585472.1
ENST00000591288.1
ENST00000502449.2
ENST00000345615.4
ENST00000346661.4
ENST00000585689.1
ENST00000339208.6
synergin, gamma
chr5_-_1524015 0.19 ENST00000283415.3
lysophosphatidylcholine acyltransferase 1
chr12_+_32112340 0.19 ENST00000540924.1
ENST00000312561.4
KIAA1551
chr1_-_179198702 0.19 ENST00000502732.1
c-abl oncogene 2, non-receptor tyrosine kinase
chr7_+_116312411 0.19 ENST00000456159.1
ENST00000397752.3
ENST00000318493.6
met proto-oncogene
chr14_-_78083112 0.19 ENST00000216484.2
serine palmitoyltransferase, long chain base subunit 2
chr3_+_32147997 0.18 ENST00000282541.5
glycerol-3-phosphate dehydrogenase 1-like
chr4_-_7873981 0.18 ENST00000360265.4
actin filament associated protein 1
chr14_-_39901618 0.18 ENST00000554932.1
ENST00000298097.7
F-box protein 33
chr11_+_14665263 0.18 ENST00000282096.4
phosphodiesterase 3B, cGMP-inhibited
chr17_+_38474489 0.18 ENST00000394089.2
ENST00000425707.3
retinoic acid receptor, alpha
chr20_+_48599506 0.18 ENST00000244050.2
snail family zinc finger 1
chr17_+_1958388 0.18 ENST00000399849.3
hypermethylated in cancer 1
chr21_+_35445827 0.18 ENST00000608209.1
ENST00000381151.3
sodium/myo-inositol cotransporter
solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
chr8_-_122653630 0.17 ENST00000303924.4
hyaluronan synthase 2
chr16_-_70719925 0.17 ENST00000338779.6
metastasis suppressor 1-like
chr1_+_38259540 0.17 ENST00000397631.3
mannosidase, endo-alpha-like
chr17_-_58603568 0.17 ENST00000083182.3
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr9_+_131102925 0.17 ENST00000372870.1
ENST00000300456.4
solute carrier family 27 (fatty acid transporter), member 4
chr3_+_36421826 0.16 ENST00000273183.3
SH3 and cysteine rich domain
chr17_+_38278530 0.16 ENST00000398532.4
male-specific lethal 1 homolog (Drosophila)
chrX_+_56259316 0.16 ENST00000468660.1
Kruppel-like factor 8
chr17_-_46692287 0.16 ENST00000239144.4
homeobox B8
chr1_-_78148324 0.16 ENST00000370801.3
ENST00000433749.1
zinc finger, ZZ-type containing 3
chr5_-_43313574 0.16 ENST00000325110.6
ENST00000433297.2
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr12_-_120687948 0.16 ENST00000458477.2
paxillin
chr6_-_90529418 0.16 ENST00000439638.1
ENST00000369393.3
ENST00000428876.1
MDN1, midasin homolog (yeast)
chr3_+_54156664 0.16 ENST00000474759.1
ENST00000288197.5
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr5_+_172483347 0.16 ENST00000522692.1
ENST00000296953.2
ENST00000540014.1
ENST00000520420.1
CREB3 regulatory factor
chr1_+_244214577 0.16 ENST00000358704.4
zinc finger and BTB domain containing 18
chr11_-_67888671 0.16 ENST00000265689.4
choline kinase alpha
chr10_-_70287231 0.16 ENST00000609923.1
solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16
chr3_-_134093395 0.16 ENST00000249883.5
angiomotin like 2
chr12_-_12419703 0.15 ENST00000543091.1
ENST00000261349.4
low density lipoprotein receptor-related protein 6
chr10_-_91403625 0.15 ENST00000322191.6
ENST00000342512.3
ENST00000371774.2
pantothenate kinase 1
chr5_-_157002775 0.15 ENST00000257527.4
ADAM metallopeptidase domain 19
chr5_+_112043186 0.15 ENST00000509732.1
ENST00000457016.1
ENST00000507379.1
adenomatous polyposis coli
chr11_-_94964354 0.15 ENST00000536441.1
sestrin 3
chr10_-_94003003 0.15 ENST00000412050.4
cytoplasmic polyadenylation element binding protein 3
chr10_+_22610124 0.15 ENST00000376663.3
BMI1 polycomb ring finger oncogene
chr8_-_89339705 0.15 ENST00000286614.6
matrix metallopeptidase 16 (membrane-inserted)
chr20_+_34700333 0.15 ENST00000441639.1
erythrocyte membrane protein band 4.1-like 1
chr2_+_113403434 0.15 ENST00000272542.3
solute carrier family 20 (phosphate transporter), member 1
chr4_-_89619386 0.15 ENST00000323061.5
nucleosome assembly protein 1-like 5
chr14_-_91526922 0.15 ENST00000418736.2
ENST00000261991.3
ribosomal protein S6 kinase, 90kDa, polypeptide 5
chr15_+_96873921 0.14 ENST00000394166.3
nuclear receptor subfamily 2, group F, member 2
chr9_-_127703333 0.14 ENST00000373555.4
golgin A1
chr22_+_31518938 0.14 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
inositol polyphosphate-5-phosphatase J
chr11_-_108369101 0.14 ENST00000323468.5
KDEL (Lys-Asp-Glu-Leu) containing 2
chr14_-_92413727 0.14 ENST00000267620.10
fibulin 5
chr4_-_170192185 0.14 ENST00000284637.9
SH3 domain containing ring finger 1
chr12_-_15942309 0.14 ENST00000544064.1
ENST00000543523.1
ENST00000536793.1
epidermal growth factor receptor pathway substrate 8
chr10_+_127408263 0.13 ENST00000337623.3
erythroid differentiation regulatory factor 1
chr3_+_137906109 0.13 ENST00000481646.1
ENST00000469044.1
ENST00000491704.1
ENST00000461600.1
armadillo repeat containing 8
chr1_+_82266053 0.13 ENST00000370715.1
ENST00000370713.1
ENST00000319517.6
ENST00000370717.2
ENST00000394879.1
ENST00000271029.4
ENST00000335786.5
latrophilin 2
chr12_+_65004292 0.13 ENST00000542104.1
ENST00000336061.2
Ras association (RalGDS/AF-6) domain family member 3
chr8_-_124286735 0.13 ENST00000395571.3
zinc fingers and homeoboxes 1
chr9_+_71320596 0.13 ENST00000265382.3
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr14_+_57735614 0.13 ENST00000261558.3
adaptor-related protein complex 5, mu 1 subunit
chr1_+_206680879 0.13 ENST00000355294.4
ENST00000367117.3
Ras association (RalGDS/AF-6) domain family member 5
chr14_+_85996471 0.13 ENST00000330753.4
fibronectin leucine rich transmembrane protein 2
chr1_-_36022979 0.13 ENST00000469892.1
ENST00000325722.3
KIAA0319-like
chrX_-_67653614 0.12 ENST00000355520.5
oligophrenin 1
chr20_-_62610982 0.12 ENST00000369886.3
ENST00000450107.1
sterile alpha motif domain containing 10
chr17_-_50237343 0.12 ENST00000575181.1
ENST00000570565.1
carbonic anhydrase X
chr13_-_49018789 0.12 ENST00000378434.4
lysophosphatidic acid receptor 6
chr2_-_164592497 0.12 ENST00000333129.3
ENST00000409634.1
fidgetin
chr18_-_72921303 0.12 ENST00000322342.3
zinc binding alcohol dehydrogenase domain containing 2
chr4_+_134070439 0.12 ENST00000264360.5
protocadherin 10
chr7_+_90225796 0.12 ENST00000380050.3
cyclin-dependent kinase 14
chr6_-_8064567 0.12 ENST00000543936.1
ENST00000397457.2
biogenesis of lysosomal organelles complex-1, subunit 5, muted
chr13_-_67804445 0.12 ENST00000456367.1
ENST00000377861.3
ENST00000544246.1
protocadherin 9
chr4_+_71768043 0.12 ENST00000502869.1
ENST00000309395.2
ENST00000396051.2
MOB kinase activator 1B
chr8_+_28351707 0.11 ENST00000537916.1
ENST00000523546.1
ENST00000240093.3
frizzled family receptor 3
chr4_-_89744457 0.11 ENST00000395002.2
family with sequence similarity 13, member A
chr19_+_38397839 0.11 ENST00000222345.6
signal-induced proliferation-associated 1 like 3
chr10_-_113943447 0.11 ENST00000369425.1
ENST00000348367.4
ENST00000423155.1
glycerol-3-phosphate acyltransferase, mitochondrial
chr17_+_30813576 0.11 ENST00000313401.3
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr11_-_77532050 0.11 ENST00000308488.6
remodeling and spacing factor 1
chr2_+_148602058 0.11 ENST00000241416.7
ENST00000535787.1
ENST00000404590.1
activin A receptor, type IIA
chr6_+_168841817 0.11 ENST00000356284.2
ENST00000354536.5
SPARC related modular calcium binding 2
chr1_-_40137710 0.11 ENST00000235628.1
5'-nucleotidase, cytosolic IA
chr6_-_119399895 0.11 ENST00000338891.7
family with sequence similarity 184, member A
chr13_-_79177673 0.11 ENST00000377208.5
POU class 4 homeobox 1
chr10_-_97321112 0.11 ENST00000607232.1
ENST00000371227.4
ENST00000371249.2
ENST00000371247.2
ENST00000371246.2
ENST00000393949.1
ENST00000353505.5
ENST00000347291.4
sorbin and SH3 domain containing 1
chr3_-_64211112 0.11 ENST00000295902.6
prickle homolog 2 (Drosophila)
chr12_-_90049828 0.11 ENST00000261173.2
ENST00000348959.3
ATPase, Ca++ transporting, plasma membrane 1
chr3_+_155588300 0.10 ENST00000496455.2
guanine monphosphate synthase
chr16_-_30107491 0.10 ENST00000566134.1
ENST00000565110.1
ENST00000398841.1
ENST00000398838.4
yippee-like 3 (Drosophila)
chr9_-_130533615 0.10 ENST00000373277.4
SH2 domain containing 3C
chr10_+_60272814 0.10 ENST00000373886.3
bicaudal C homolog 1 (Drosophila)
chr11_+_125034586 0.10 ENST00000298282.9
PBX/knotted 1 homeobox 2
chr6_+_157099036 0.10 ENST00000350026.5
ENST00000346085.5
ENST00000367148.1
ENST00000275248.4
AT rich interactive domain 1B (SWI1-like)
chr16_+_1031762 0.10 ENST00000293894.3
SRY (sex determining region Y)-box 8
chr17_-_49337392 0.10 ENST00000376381.2
ENST00000586178.1
mbt domain containing 1
chr3_+_98451275 0.10 ENST00000265261.6
ENST00000497008.1
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr1_-_23886285 0.10 ENST00000374561.5
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr11_+_72929319 0.10 ENST00000393597.2
ENST00000311131.2
purinergic receptor P2Y, G-protein coupled, 2
chr5_+_53813536 0.10 ENST00000343017.6
ENST00000381410.4
ENST00000326277.3
sorting nexin 18
chr1_+_211433275 0.10 ENST00000367005.4
REST corepressor 3
chr13_+_28813645 0.10 ENST00000282391.5
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr11_-_86666427 0.10 ENST00000531380.1
frizzled family receptor 4
chr6_+_142622991 0.10 ENST00000230173.6
ENST00000367608.2
G protein-coupled receptor 126
chr17_-_37557846 0.10 ENST00000394294.3
ENST00000583610.1
ENST00000264658.6
F-box and leucine-rich repeat protein 20
chr5_-_93447333 0.09 ENST00000395965.3
ENST00000505869.1
ENST00000509163.1
family with sequence similarity 172, member A
chr1_+_113933581 0.09 ENST00000307546.9
ENST00000369615.1
ENST00000369611.4
membrane associated guanylate kinase, WW and PDZ domain containing 3
chr14_+_37131058 0.09 ENST00000361487.6
paired box 9
chr12_+_83080659 0.09 ENST00000321196.3
transmembrane and tetratricopeptide repeat containing 2
chr7_-_5463175 0.09 ENST00000399537.4
ENST00000430969.1
trinucleotide repeat containing 18
chr16_-_73082274 0.09 ENST00000268489.5
zinc finger homeobox 3
chr9_-_135819987 0.09 ENST00000298552.3
ENST00000403810.1
tuberous sclerosis 1
chr9_-_130742792 0.09 ENST00000373095.1
family with sequence similarity 102, member A
chr14_+_52734401 0.09 ENST00000306051.2
ENST00000553372.1
prostaglandin D2 receptor (DP)
chr15_+_81071684 0.09 ENST00000220244.3
ENST00000394685.3
ENST00000356249.5
KIAA1199
chr9_+_109625378 0.09 ENST00000277225.5
ENST00000457913.1
ENST00000472574.1
zinc finger protein 462
chr20_+_57226284 0.09 ENST00000458280.1
ENST00000355957.5
ENST00000361770.5
ENST00000312283.8
ENST00000412911.1
ENST00000359617.4
ENST00000371141.4
syntaxin 16
chr14_-_90085458 0.09 ENST00000345097.4
ENST00000555855.1
ENST00000555353.1
forkhead box N3
chr18_-_74207146 0.09 ENST00000443185.2
zinc finger protein 516
chr12_-_54813229 0.09 ENST00000293379.4
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr5_+_76326187 0.09 ENST00000312916.7
ENST00000506806.1
angiogenic factor with G patch and FHA domains 1
chrX_-_129402857 0.09 ENST00000447817.1
ENST00000370978.4
zinc finger protein 280C
chr5_-_59995921 0.09 ENST00000453022.2
ENST00000545085.1
ENST00000265036.5
DEP domain containing 1B
chr5_-_132948216 0.08 ENST00000265342.7
follistatin-like 4
chr19_-_11450249 0.08 ENST00000222120.3
RAB3D, member RAS oncogene family
chr5_-_176981417 0.08 ENST00000514747.1
ENST00000443375.2
ENST00000329540.5
family with sequence similarity 193, member B
chr1_+_220701456 0.08 ENST00000366918.4
ENST00000402574.1
MAP/microtubule affinity-regulating kinase 1
chr14_-_64194745 0.08 ENST00000247225.6
sphingosine-1-phosphate phosphatase 1
chr17_+_25621102 0.08 ENST00000581440.1
ENST00000262394.2
ENST00000583742.1
ENST00000579733.1
ENST00000583193.1
ENST00000581185.1
ENST00000427287.2
ENST00000348811.2
WD repeat and SOCS box containing 1
chr12_+_72056773 0.08 ENST00000308086.2
THAP domain containing, apoptosis associated protein 2

Network of associatons between targets according to the STRING database.

First level regulatory network of UCACAGU

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0060435 bronchiole development(GO:0060435)
0.2 0.6 GO:0060995 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.1 0.6 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.1 0.5 GO:0072554 blood vessel lumenization(GO:0072554)
0.1 0.9 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.1 0.4 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076) positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.1 0.3 GO:0035854 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.1 0.5 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.1 0.4 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1 0.3 GO:0033341 regulation of collagen binding(GO:0033341)
0.1 0.3 GO:0003363 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.1 0.3 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.1 0.2 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.1 0.5 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.2 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.1 0.3 GO:0007538 primary sex determination(GO:0007538)
0.1 0.2 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.1 0.2 GO:0006667 sphinganine metabolic process(GO:0006667)
0.1 0.2 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.3 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.1 0.5 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 0.2 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1 0.3 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.1 GO:0072034 renal vesicle induction(GO:0072034)
0.0 0.1 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.0 0.4 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.2 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.0 0.3 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 0.2 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.3 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.3 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.2 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.4 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.3 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.1 GO:0045976 negative regulation of mitotic cell cycle, embryonic(GO:0045976)
0.0 0.3 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.1 GO:0021722 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.0 0.2 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 0.1 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.0 0.1 GO:0009956 radial pattern formation(GO:0009956)
0.0 0.1 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.0 0.2 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.2 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.4 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.2 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.0 0.5 GO:0015866 ADP transport(GO:0015866)
0.0 0.1 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.3 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 0.2 GO:0015798 myo-inositol transport(GO:0015798)
0.0 0.1 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 0.2 GO:0018211 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.1 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.5 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0003257 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
0.0 0.3 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 0.1 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.0 1.1 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.3 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.1 GO:0051029 rRNA transport(GO:0051029)
0.0 0.0 GO:0035947 regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947)
0.0 0.1 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 0.1 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.0 0.1 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 0.2 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.0 0.0 GO:0061312 BMP signaling pathway involved in heart development(GO:0061312)
0.0 0.1 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.0 0.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.2 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.6 GO:0060065 uterus development(GO:0060065)
0.0 0.1 GO:0042713 sperm ejaculation(GO:0042713)
0.0 0.1 GO:0002071 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.1 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.0 0.5 GO:0051412 response to corticosterone(GO:0051412)
0.0 0.2 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.1 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.0 0.4 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.0 GO:0060722 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.0 0.0 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 0.2 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.0 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.3 GO:0010666 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.0 0.1 GO:0097070 ductus arteriosus closure(GO:0097070)
0.0 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.1 GO:0097466 protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.0 0.2 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.1 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.0 0.1 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.1 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.6 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.1 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.2 GO:0072189 ureter development(GO:0072189)
0.0 0.0 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.1 GO:0051541 elastin metabolic process(GO:0051541)
0.0 0.2 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.0 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.1 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.4 GO:0097503 sialylation(GO:0097503)
0.0 0.1 GO:0036089 cleavage furrow formation(GO:0036089)
0.0 0.3 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.1 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.2 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.0 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.0 0.1 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.0 0.3 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.1 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.0 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.3 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.1 0.2 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0 0.4 GO:0000125 PCAF complex(GO:0000125)
0.0 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:0031213 RSF complex(GO:0031213)
0.0 0.1 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.2 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 0.3 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.1 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.1 GO:0071953 elastic fiber(GO:0071953)
0.0 0.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.2 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.0 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.0 0.2 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.0 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.0 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.1 0.4 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 0.2 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.2 GO:0031177 S-acetyltransferase activity(GO:0016418) phosphopantetheine binding(GO:0031177)
0.1 0.5 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.2 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.1 0.4 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 0.2 GO:0004103 choline kinase activity(GO:0004103)
0.1 0.3 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.2 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.3 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.0 0.3 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.4 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.1 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.0 0.2 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.5 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.6 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.5 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.1 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.0 0.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.4 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.1 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.5 GO:0005112 Notch binding(GO:0005112)
0.0 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0047522 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 0.1 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.0 0.0 GO:0001034 RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.0 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445) phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.0 0.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.0 GO:0090541 MIT domain binding(GO:0090541)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.1 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.1 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.0 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.1 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.0 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.0 0.0 GO:0031862 prostanoid receptor binding(GO:0031862)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.1 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.1 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.4 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.5 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.4 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.0 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.0 0.3 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.0 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.4 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.3 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism