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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for UCACAUU

Z-value: 0.49

Motif logo

miRNA associated with seed UCACAUU

NamemiRBASE accession
MIMAT0000078
MIMAT0000418
MIMAT0018000
MIMAT0004593

Activity profile of UCACAUU motif

Sorted Z-values of UCACAUU motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_131762105 1.65 ENST00000368648.3
ENST00000355311.5
early B-cell factor 3
chr12_+_20522179 1.60 ENST00000359062.3
phosphodiesterase 3A, cGMP-inhibited
chr1_-_92351769 1.43 ENST00000212355.4
transforming growth factor, beta receptor III
chr8_-_93115445 1.38 ENST00000523629.1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr8_-_28243934 1.12 ENST00000521185.1
ENST00000520290.1
ENST00000344423.5
zinc finger protein 395
chr3_-_18466787 0.94 ENST00000338745.6
ENST00000450898.1
SATB homeobox 1
chr8_-_22550815 0.91 ENST00000317216.2
early growth response 3
chr12_+_13197218 0.89 ENST00000197268.8
KIAA1467
chr7_+_114562172 0.87 ENST00000393486.1
ENST00000257724.3
MyoD family inhibitor domain containing
chr13_+_58206655 0.86 ENST00000377918.3
protocadherin 17
chr9_-_14314066 0.78 ENST00000397575.3
nuclear factor I/B
chr4_+_123747834 0.77 ENST00000264498.3
fibroblast growth factor 2 (basic)
chr2_+_148778570 0.74 ENST00000407073.1
methyl-CpG binding domain protein 5
chr1_+_61547894 0.72 ENST00000403491.3
nuclear factor I/A
chr6_-_16761678 0.70 ENST00000244769.4
ENST00000436367.1
ataxin 1
chr7_+_116312411 0.67 ENST00000456159.1
ENST00000397752.3
ENST00000318493.6
met proto-oncogene
chr2_+_159313452 0.67 ENST00000389757.3
ENST00000389759.3
plakophilin 4
chrX_+_118108571 0.67 ENST00000304778.7
LON peptidase N-terminal domain and ring finger 3
chr11_-_130184555 0.62 ENST00000525842.1
zinc finger and BTB domain containing 44
chr13_-_72441315 0.61 ENST00000305425.4
ENST00000313174.7
ENST00000354591.4
dachshund homolog 1 (Drosophila)
chr6_+_15246501 0.61 ENST00000341776.2
jumonji, AT rich interactive domain 2
chr5_-_73937244 0.59 ENST00000302351.4
ENST00000510316.1
ENST00000508331.1
ectodermal-neural cortex 1 (with BTB domain)
chr1_+_78470530 0.57 ENST00000370763.5
DnaJ (Hsp40) homolog, subfamily B, member 4
chr8_-_71316021 0.55 ENST00000452400.2
nuclear receptor coactivator 2
chr10_+_103986085 0.54 ENST00000370005.3
ELOVL fatty acid elongase 3
chr1_+_65730385 0.54 ENST00000263441.7
ENST00000395325.3
DnaJ (Hsp40) homolog, subfamily C, member 6
chr11_-_94964354 0.53 ENST00000536441.1
sestrin 3
chr1_+_82266053 0.52 ENST00000370715.1
ENST00000370713.1
ENST00000319517.6
ENST00000370717.2
ENST00000394879.1
ENST00000271029.4
ENST00000335786.5
latrophilin 2
chr13_+_80055284 0.51 ENST00000218652.7
Nedd4 family interacting protein 2
chr12_-_95044309 0.49 ENST00000261226.4
transmembrane and coiled-coil domain family 3
chr11_-_66115032 0.47 ENST00000311181.4
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
chr2_+_46524537 0.46 ENST00000263734.3
endothelial PAS domain protein 1
chr8_-_124553437 0.45 ENST00000517956.1
ENST00000443022.2
F-box protein 32
chr19_+_1026298 0.43 ENST00000263097.4
calponin 2
chrX_+_46433193 0.43 ENST00000276055.3
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
chr22_+_40573921 0.43 ENST00000454349.2
ENST00000335727.9
trinucleotide repeat containing 6B
chr6_+_119215308 0.43 ENST00000229595.5
anti-silencing function 1A histone chaperone
chr4_-_16900217 0.42 ENST00000441778.2
LIM domain binding 2
chr11_+_68080077 0.42 ENST00000294304.7
low density lipoprotein receptor-related protein 5
chr1_+_66797687 0.41 ENST00000371045.5
ENST00000531025.1
ENST00000526197.1
phosphodiesterase 4B, cAMP-specific
chrX_+_9754461 0.40 ENST00000380913.3
shroom family member 2
chr9_+_4490394 0.40 ENST00000262352.3
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr16_+_53468332 0.40 ENST00000262133.6
retinoblastoma-like 2 (p130)
chr4_+_145567173 0.39 ENST00000296575.3
hedgehog interacting protein
chr12_+_27396901 0.39 ENST00000541191.1
ENST00000389032.3
serine/threonine kinase 38 like
chr19_+_45973120 0.38 ENST00000592811.1
ENST00000586615.1
FBJ murine osteosarcoma viral oncogene homolog B
chr10_+_89622870 0.37 ENST00000371953.3
phosphatase and tensin homolog
chr4_-_78740511 0.37 ENST00000504123.1
ENST00000264903.4
ENST00000515441.1
CCR4-NOT transcription complex, subunit 6-like
chr7_-_11871815 0.36 ENST00000423059.4
thrombospondin, type I, domain containing 7A
chr1_+_198126093 0.35 ENST00000367385.4
ENST00000442588.1
ENST00000538004.1
NIMA-related kinase 7
chr12_+_32655048 0.35 ENST00000427716.2
ENST00000266482.3
FYVE, RhoGEF and PH domain containing 4
chr1_+_164528866 0.34 ENST00000420696.2
pre-B-cell leukemia homeobox 1
chr4_+_87856129 0.33 ENST00000395146.4
ENST00000507468.1
AF4/FMR2 family, member 1
chr20_+_39657454 0.33 ENST00000361337.2
topoisomerase (DNA) I
chr7_-_120498357 0.33 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
tetraspanin 12
chr1_+_93913713 0.32 ENST00000604705.1
ENST00000370253.2
formin binding protein 1-like
chr8_-_66754172 0.32 ENST00000401827.3
phosphodiesterase 7A
chr17_+_58677539 0.32 ENST00000305921.3
protein phosphatase, Mg2+/Mn2+ dependent, 1D
chr6_+_110501344 0.31 ENST00000368932.1
cell division cycle 40
chr10_-_125851961 0.31 ENST00000346248.5
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr9_+_115513003 0.31 ENST00000374232.3
sorting nexin family member 30
chr1_-_9970227 0.30 ENST00000377263.1
catenin, beta interacting protein 1
chr20_-_36156125 0.30 ENST00000397135.1
ENST00000397137.1
bladder cancer associated protein
chr4_-_102268628 0.30 ENST00000323055.6
ENST00000512215.1
ENST00000394854.3
protein phosphatase 3, catalytic subunit, alpha isozyme
chr2_+_207139367 0.30 ENST00000374423.3
zinc finger, DBF-type containing 2
chr12_+_96588143 0.30 ENST00000228741.3
ENST00000547249.1
ELK3, ETS-domain protein (SRF accessory protein 2)
chr20_+_37434329 0.29 ENST00000299824.1
ENST00000373331.2
protein phosphatase 1, regulatory subunit 16B
chr10_+_112631547 0.28 ENST00000280154.7
ENST00000393104.2
programmed cell death 4 (neoplastic transformation inhibitor)
chr1_+_66999799 0.27 ENST00000371035.3
ENST00000371036.3
ENST00000371037.4
SH3-domain GRB2-like (endophilin) interacting protein 1
chr18_+_60190226 0.27 ENST00000269499.5
zinc finger, CCHC domain containing 2
chr4_-_125633876 0.27 ENST00000504087.1
ENST00000515641.1
ankyrin repeat domain 50
chr2_+_45878790 0.26 ENST00000306156.3
protein kinase C, epsilon
chr4_+_144257915 0.26 ENST00000262995.4
GRB2-associated binding protein 1
chr3_-_28390581 0.26 ENST00000479665.1
5-azacytidine induced 2
chr15_-_71055878 0.26 ENST00000322954.6
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr6_+_151561085 0.25 ENST00000402676.2
A kinase (PRKA) anchor protein 12
chr16_+_67596310 0.25 ENST00000264010.4
ENST00000401394.1
CCCTC-binding factor (zinc finger protein)
chr6_-_8064567 0.25 ENST00000543936.1
ENST00000397457.2
biogenesis of lysosomal organelles complex-1, subunit 5, muted
chr7_+_65338230 0.25 ENST00000360768.3
vitamin K epoxide reductase complex, subunit 1-like 1
chr1_+_150337144 0.25 ENST00000539519.1
ENST00000369067.3
ENST00000369068.4
regulation of nuclear pre-mRNA domain containing 2
chr11_+_47291193 0.25 ENST00000428807.1
ENST00000402799.1
ENST00000406482.1
ENST00000349238.3
ENST00000311027.5
ENST00000407859.3
ENST00000395344.3
ENST00000444117.1
MAP-kinase activating death domain
chr17_-_49337392 0.25 ENST00000376381.2
ENST00000586178.1
mbt domain containing 1
chr12_+_72233487 0.24 ENST00000482439.2
ENST00000550746.1
ENST00000491063.1
ENST00000319106.8
ENST00000485960.2
ENST00000393309.3
TBC1 domain family, member 15
chr7_+_69064300 0.24 ENST00000342771.4
autism susceptibility candidate 2
chr8_-_81083731 0.24 ENST00000379096.5
tumor protein D52
chr6_+_41606176 0.24 ENST00000441667.1
ENST00000230321.6
ENST00000373050.4
ENST00000446650.1
ENST00000435476.1
MyoD family inhibitor
chr20_-_31071239 0.24 ENST00000359676.5
chromosome 20 open reading frame 112
chr4_+_154387480 0.23 ENST00000409663.3
ENST00000440693.1
ENST00000409959.3
KIAA0922
chr2_-_164592497 0.23 ENST00000333129.3
ENST00000409634.1
fidgetin
chr14_-_35182994 0.23 ENST00000341223.3
cofilin 2 (muscle)
chr15_+_52043758 0.23 ENST00000249700.4
ENST00000539962.2
tropomodulin 2 (neuronal)
chr8_-_103668114 0.23 ENST00000285407.6
Kruppel-like factor 10
chr1_+_244214577 0.22 ENST00000358704.4
zinc finger and BTB domain containing 18
chr13_+_27131887 0.22 ENST00000335327.5
WAS protein family, member 3
chr16_-_19896220 0.22 ENST00000562469.1
ENST00000300571.2
G protein-coupled receptor, family C, group 5, member B
chr4_-_76439596 0.22 ENST00000451788.1
ENST00000512706.1
ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
chr15_-_31283798 0.22 ENST00000435680.1
ENST00000425768.1
myotubularin related protein 10
chr14_+_103058948 0.22 ENST00000262241.6
REST corepressor 1
chr10_+_17851362 0.22 ENST00000331429.2
ENST00000457317.1
cDNA FLJ56855, highly similar to Macrophage mannose receptor 1
chr8_-_91658303 0.22 ENST00000458549.2
transmembrane protein 64
chr10_-_65225722 0.22 ENST00000399251.1
jumonji domain containing 1C
chrX_+_105066524 0.21 ENST00000243300.9
ENST00000428173.2
Nik related kinase
chr11_+_86748863 0.21 ENST00000340353.7
transmembrane protein 135
chr8_+_76452097 0.21 ENST00000396423.2
hepatocyte nuclear factor 4, gamma
chr8_+_26240414 0.21 ENST00000380629.2
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr11_+_133938820 0.20 ENST00000299106.4
ENST00000529443.2
junctional adhesion molecule 3
chr2_-_160472952 0.20 ENST00000541068.2
ENST00000355831.2
ENST00000343439.5
ENST00000392782.1
bromodomain adjacent to zinc finger domain, 2B
chrX_+_73641286 0.20 ENST00000587091.1
solute carrier family 16, member 2 (thyroid hormone transporter)
chr13_-_79233314 0.20 ENST00000282003.6
ring finger protein 219
chr5_+_137801160 0.19 ENST00000239938.4
early growth response 1
chr3_-_113233992 0.19 ENST00000295872.4
ENST00000480527.1
spindle and centriole associated protein 1
chr19_-_31840438 0.19 ENST00000240587.4
teashirt zinc finger homeobox 3
chr19_+_1249869 0.19 ENST00000591446.2
midnolin
chr17_-_66287257 0.19 ENST00000327268.4
solute carrier family 16, member 6
chr1_+_154377669 0.19 ENST00000368485.3
ENST00000344086.4
interleukin 6 receptor
chr10_+_99079008 0.18 ENST00000371021.3
frequently rearranged in advanced T-cell lymphomas
chr6_+_143929307 0.18 ENST00000427704.2
ENST00000305766.6
phosphatase and actin regulator 2
chr9_-_16870704 0.18 ENST00000380672.4
ENST00000380667.2
ENST00000380666.2
ENST00000486514.1
basonuclin 2
chr17_+_45608430 0.18 ENST00000322157.4
aminopeptidase puromycin sensitive
chr9_+_91003271 0.17 ENST00000375859.3
ENST00000541629.1
spindlin 1
chr10_+_112836779 0.17 ENST00000280155.2
adrenoceptor alpha 2A
chr3_+_134204881 0.17 ENST00000511574.1
ENST00000337090.3
ENST00000383229.3
centrosomal protein 63kDa
chr7_+_94139105 0.17 ENST00000297273.4
CAS1 domain containing 1
chr2_+_170683942 0.17 ENST00000272793.5
ubiquitin protein ligase E3 component n-recognin 3 (putative)
chr17_+_60704762 0.17 ENST00000303375.5
mannose receptor, C type 2
chr1_+_107599267 0.17 ENST00000361318.5
ENST00000370078.1
protein arginine methyltransferase 6
chr1_-_225615599 0.16 ENST00000421383.1
ENST00000272163.4
lamin B receptor
chr4_+_159131346 0.16 ENST00000508243.1
ENST00000296529.6
transmembrane protein 144
chr6_+_153019023 0.16 ENST00000367245.5
ENST00000529453.1
myc target 1
chr5_+_118407053 0.15 ENST00000311085.8
ENST00000539542.1
Dmx-like 1
chr2_-_209119831 0.15 ENST00000345146.2
isocitrate dehydrogenase 1 (NADP+), soluble
chr8_-_60031762 0.15 ENST00000361421.1
thymocyte selection-associated high mobility group box
chr17_-_36956155 0.15 ENST00000269554.3
phosphatidylinositol-5-phosphate 4-kinase, type II, beta
chr11_-_110583451 0.15 ENST00000260283.4
ENST00000528829.1
Rho GTPase activating protein 20
chr6_-_116575226 0.15 ENST00000420283.1
TSPY-like 4
chr2_-_183903133 0.15 ENST00000361354.4
NCK-associated protein 1
chr8_+_37594130 0.15 ENST00000518526.1
ENST00000523887.1
ENST00000276461.5
ER lipid raft associated 2
chr17_+_61086917 0.15 ENST00000424789.2
ENST00000389520.4
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr5_-_158757895 0.15 ENST00000231228.2
interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
chr15_-_44486632 0.15 ENST00000484674.1
FERM domain containing 5
chr12_+_104324112 0.15 ENST00000299767.5
heat shock protein 90kDa beta (Grp94), member 1
chr7_-_93520259 0.15 ENST00000222543.5
tissue factor pathway inhibitor 2
chr4_+_170541660 0.15 ENST00000513761.1
ENST00000347613.4
chloride channel, voltage-sensitive 3
chr9_-_125027079 0.14 ENST00000417201.3
RNA binding motif protein 18
chr1_-_20812690 0.14 ENST00000375078.3
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr17_+_25799008 0.14 ENST00000583370.1
ENST00000398988.3
ENST00000268763.6
kinase suppressor of ras 1
chr5_-_133747589 0.14 ENST00000458198.2
CDKN2A interacting protein N-terminal like
chr8_+_74206829 0.14 ENST00000240285.5
retinol dehydrogenase 10 (all-trans)
chr7_-_93633684 0.14 ENST00000222547.3
ENST00000425626.1
Bet1 golgi vesicular membrane trafficking protein
chr6_+_87865262 0.14 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
zinc finger protein 292
chr12_-_42538657 0.14 ENST00000398675.3
glucoside xylosyltransferase 1
chr1_+_112162381 0.13 ENST00000433097.1
ENST00000369709.3
ENST00000436150.2
RAP1A, member of RAS oncogene family
chr2_-_179343268 0.13 ENST00000424785.2
FK506 binding protein 7
chr10_+_112257596 0.13 ENST00000369583.3
dual specificity phosphatase 5
chr16_-_17564738 0.13 ENST00000261381.6
xylosyltransferase I
chr10_-_101989315 0.13 ENST00000370397.7
conserved helix-loop-helix ubiquitous kinase
chr2_-_172017343 0.12 ENST00000431350.2
ENST00000360843.3
tousled-like kinase 1
chr2_-_70475730 0.12 ENST00000445587.1
ENST00000433529.2
ENST00000415783.2
TIA1 cytotoxic granule-associated RNA binding protein
chr3_+_107241783 0.12 ENST00000415149.2
ENST00000402543.1
ENST00000325805.8
ENST00000427402.1
bobby sox homolog (Drosophila)
chr1_-_24194771 0.12 ENST00000374479.3
fucosidase, alpha-L- 1, tissue
chr2_+_42275153 0.12 ENST00000294964.5
protein kinase domain containing, cytoplasmic
chr21_-_40685477 0.12 ENST00000342449.3
bromodomain and WD repeat domain containing 1
chr11_-_96076334 0.12 ENST00000524717.1
mastermind-like 2 (Drosophila)
chr10_-_102279586 0.12 ENST00000370345.3
ENST00000451524.1
ENST00000370329.5
SEC31 homolog B (S. cerevisiae)
chr3_+_31574189 0.12 ENST00000295770.2
STT3B, subunit of the oligosaccharyltransferase complex (catalytic)
chr9_+_33817461 0.12 ENST00000263228.3
ubiquitin-conjugating enzyme E2R 2
chr4_+_84457250 0.12 ENST00000395226.2
1-acylglycerol-3-phosphate O-acyltransferase 9
chr7_+_77325738 0.11 ENST00000334955.8
round spermatid basic protein 1-like
chr5_-_77844974 0.11 ENST00000515007.2
lipoma HMGIC fusion partner-like 2
chr8_+_86376081 0.11 ENST00000285379.5
carbonic anhydrase II
chr16_-_58231782 0.11 ENST00000565188.1
ENST00000262506.3
casein kinase 2, alpha prime polypeptide
chr4_-_140098339 0.11 ENST00000394235.2
E74-like factor 2 (ets domain transcription factor)
chrX_-_64196307 0.11 ENST00000545618.1
zinc finger, C4H2 domain containing
chr12_+_22778009 0.11 ENST00000266517.4
ENST00000335148.3
ethanolamine kinase 1
chr13_-_100624012 0.11 ENST00000267294.4
Zic family member 5
chr21_-_47706205 0.11 ENST00000397708.1
minichromosome maintenance complex component 3 associated protein
chr3_-_171178157 0.11 ENST00000465393.1
ENST00000436636.2
ENST00000369326.5
ENST00000538048.1
ENST00000341852.6
TRAF2 and NCK interacting kinase
chr7_-_123197733 0.11 ENST00000470123.1
ENST00000471770.1
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr3_-_138665969 0.11 ENST00000330315.3
forkhead box L2
chr4_+_79697495 0.11 ENST00000502871.1
ENST00000335016.5
BMP2 inducible kinase
chrX_+_115567767 0.11 ENST00000371900.4
solute carrier family 6 (amino acid transporter), member 14
chr5_-_76383133 0.11 ENST00000255198.2
zinc finger, BED-type containing 3
chrX_+_28605516 0.10 ENST00000378993.1
interleukin 1 receptor accessory protein-like 1
chr17_-_65241281 0.10 ENST00000358691.5
ENST00000580168.1
helicase with zinc finger
chr5_+_140227048 0.10 ENST00000532602.1
protocadherin alpha 9
chr7_+_99613195 0.10 ENST00000324306.6
zinc finger with KRAB and SCAN domains 1
chr5_+_140248518 0.10 ENST00000398640.2
protocadherin alpha 11
chr14_-_39901618 0.10 ENST00000554932.1
ENST00000298097.7
F-box protein 33
chr9_-_135230336 0.10 ENST00000224140.5
ENST00000372169.2
ENST00000393220.1
senataxin
chr12_+_72056773 0.10 ENST00000308086.2
THAP domain containing, apoptosis associated protein 2
chr5_+_140213815 0.10 ENST00000525929.1
ENST00000378125.3
protocadherin alpha 7
chr11_+_113930291 0.10 ENST00000335953.4
zinc finger and BTB domain containing 16
chr5_+_140220769 0.10 ENST00000531613.1
ENST00000378123.3
protocadherin alpha 8
chr5_-_162887071 0.10 ENST00000302764.4
NudC domain containing 2
chr9_+_100395891 0.10 ENST00000375147.3
nuclear cap binding protein subunit 1, 80kDa
chr3_+_88188254 0.10 ENST00000309495.5
zinc finger protein 654
chrX_+_44732757 0.10 ENST00000377967.4
ENST00000536777.1
ENST00000382899.4
ENST00000543216.1
lysine (K)-specific demethylase 6A
chr8_+_22457127 0.10 ENST00000289989.5
chromosome 8 open reading frame 58
chr3_-_87040233 0.09 ENST00000398399.2
vestigial like 3 (Drosophila)
chr1_+_200708671 0.09 ENST00000358823.2
calmodulin regulated spectrin-associated protein family, member 2

Network of associatons between targets according to the STRING database.

First level regulatory network of UCACAUU

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.4 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.3 1.6 GO:0071321 cellular response to cGMP(GO:0071321)
0.1 1.1 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
0.1 0.7 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1 0.6 GO:1904016 response to Thyroglobulin triiodothyronine(GO:1904016)
0.1 0.7 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.1 0.8 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 0.8 GO:2000546 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.1 0.4 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.1 0.8 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.1 0.3 GO:0060938 cardiac fibroblast cell differentiation(GO:0060935) cardiac fibroblast cell development(GO:0060936) epicardium-derived cardiac fibroblast cell differentiation(GO:0060938) epicardium-derived cardiac fibroblast cell development(GO:0060939) epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.1 0.3 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.1 0.3 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.1 0.3 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.1 0.6 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.1 0.2 GO:0035669 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.1 0.2 GO:0060721 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.1 0.2 GO:0050720 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) interleukin-1 beta biosynthetic process(GO:0050720) response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.1 0.2 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 0.2 GO:0002384 hepatic immune response(GO:0002384)
0.1 0.5 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 0.5 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.6 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.5 GO:0043129 surfactant homeostasis(GO:0043129)
0.1 0.2 GO:0034970 histone H3-R2 methylation(GO:0034970)
0.1 0.2 GO:0006097 glyoxylate cycle(GO:0006097)
0.1 0.3 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.4 GO:0000101 sulfur amino acid transport(GO:0000101) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:0031247 actin rod assembly(GO:0031247)
0.0 0.4 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.3 GO:0010216 maintenance of DNA methylation(GO:0010216) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0 0.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.5 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.4 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.2 GO:0035625 negative regulation of epinephrine secretion(GO:0032811) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.0 0.1 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.3 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.1 GO:0042938 dipeptide transport(GO:0042938)
0.0 0.2 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.5 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.4 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.6 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.2 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.2 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.1 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.8 GO:0060004 reflex(GO:0060004)
0.0 0.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.2 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.2 GO:0001555 oocyte growth(GO:0001555)
0.0 0.2 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.2 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.0 0.1 GO:2000417 negative regulation of eosinophil migration(GO:2000417)
0.0 0.7 GO:0043482 pigment accumulation(GO:0043476) cellular pigment accumulation(GO:0043482)
0.0 0.1 GO:0032618 interleukin-15 production(GO:0032618)
0.0 0.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.5 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.4 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.1 GO:0051142 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0 0.1 GO:0010645 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.2 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.1 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.1 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.0 0.1 GO:0060431 primary lung bud formation(GO:0060431)
0.0 0.3 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 0.1 GO:1901873 regulation of post-translational protein modification(GO:1901873)
0.0 0.1 GO:0046125 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0 0.2 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.4 GO:0006265 DNA topological change(GO:0006265)
0.0 0.1 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.1 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.1 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.0 0.1 GO:0061582 intestinal epithelial cell migration(GO:0061582)
0.0 0.6 GO:0060074 synapse maturation(GO:0060074)
0.0 0.0 GO:0019085 early viral transcription(GO:0019085)
0.0 0.4 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.0 0.1 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.0 0.1 GO:1905216 positive regulation of RNA binding(GO:1905216)
0.0 0.1 GO:0072642 interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0015798 myo-inositol transport(GO:0015798)
0.0 0.0 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.0 0.2 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.0 GO:1900158 negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.0 0.1 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0 0.1 GO:0097676 cell migration involved in vasculogenesis(GO:0035441) histone H3-K36 dimethylation(GO:0097676)
0.0 0.9 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.0 0.2 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.2 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.2 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0 0.1 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.2 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.4 GO:0010669 epithelial structure maintenance(GO:0010669)
0.0 0.3 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 0.3 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.1 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.0 0.1 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.0 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.0 0.0 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.0 0.0 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.0 0.1 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.0 0.2 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.7 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.0 GO:2000537 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.0 0.0 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.3 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.4 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:1902019 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0 0.1 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.1 GO:0075044 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.3 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.4 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.4 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.1 0.3 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.1 0.7 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 0.2 GO:0043291 RAVE complex(GO:0043291)
0.0 0.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.7 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.3 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.7 GO:0010369 chromocenter(GO:0010369)
0.0 0.1 GO:0005846 nuclear cap binding complex(GO:0005846)
0.0 0.8 GO:0030057 desmosome(GO:0030057)
0.0 0.9 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.5 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.2 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.1 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 0.4 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.1 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 0.1 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.0 2.6 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.1 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.7 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.1 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.1 GO:0031906 late endosome lumen(GO:0031906)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.4 GO:0031092 platelet alpha granule membrane(GO:0031092)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.1 0.5 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.7 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.3 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.3 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.1 0.4 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.1 1.0 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 0.2 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.1 0.5 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.4 GO:0097108 hedgehog family protein binding(GO:0097108)
0.1 0.2 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.1 0.3 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 0.2 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.1 0.9 GO:0030957 Tat protein binding(GO:0030957)
0.1 0.2 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450) (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.1 0.2 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.3 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.0 0.1 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 0.3 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.4 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.2 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.1 GO:0004560 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.0 0.3 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.0 0.3 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.6 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.3 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.1 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.0 0.2 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.1 GO:0004137 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.0 0.4 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.9 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.8 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.0 0.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.0 0.7 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.0 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.6 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.2 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.0 0.1 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.0 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.1 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.1 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.5 PID FGF PATHWAY FGF signaling pathway
0.0 0.7 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 1.2 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.1 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.6 PID HIF2PATHWAY HIF-2-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 1.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.1 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.4 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.8 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.5 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.4 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.7 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.6 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.5 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.5 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.3 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling