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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for UGGUCCC

Z-value: 0.78

Motif logo

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miRNA associated with seed UGGUCCC

NamemiRBASE accession
hsa-miR-133a-3p.1

Activity profile of UGGUCCC motif

Sorted Z-values of UGGUCCC motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_208030647 1.94 ENST00000309446.6
KLF7
Kruppel-like factor 7 (ubiquitous)
chr6_-_134639180 1.71 ENST00000367858.5
SGK1
serum/glucocorticoid regulated kinase 1
chr16_+_50775948 1.61 ENST00000569681.1
ENST00000569418.1
ENST00000540145.1
CYLD
cylindromatosis (turban tumor syndrome)
chr6_-_10415470 1.55 ENST00000379604.2
ENST00000379613.3
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr6_-_82462425 1.45 ENST00000369754.3
ENST00000320172.6
ENST00000369756.3
FAM46A
family with sequence similarity 46, member A
chr8_-_37756972 1.26 ENST00000330843.4
ENST00000522727.1
ENST00000287263.4
RAB11FIP1
RAB11 family interacting protein 1 (class I)
chr1_+_165796753 1.21 ENST00000367879.4
UCK2
uridine-cytidine kinase 2
chr3_-_107809816 1.11 ENST00000361309.5
ENST00000355354.7
CD47
CD47 molecule
chr7_+_28452130 1.10 ENST00000357727.2
CREB5
cAMP responsive element binding protein 5
chr7_+_100728720 1.07 ENST00000306085.6
ENST00000412507.1
TRIM56
tripartite motif containing 56
chr1_+_155108294 1.05 ENST00000303343.8
ENST00000368404.4
ENST00000368401.5
SLC50A1
solute carrier family 50 (sugar efflux transporter), member 1
chr8_-_103876965 1.02 ENST00000337198.5
AZIN1
antizyme inhibitor 1
chr1_-_159893507 0.97 ENST00000368096.1
TAGLN2
transgelin 2
chr6_-_128841503 0.92 ENST00000368215.3
ENST00000532331.1
ENST00000368213.5
ENST00000368207.3
ENST00000525459.1
ENST00000368210.3
ENST00000368226.4
ENST00000368227.3
PTPRK
protein tyrosine phosphatase, receptor type, K
chr19_-_10444188 0.91 ENST00000293677.6
RAVER1
ribonucleoprotein, PTB-binding 1
chr8_-_134309335 0.87 ENST00000522890.1
ENST00000323851.7
ENST00000518176.1
ENST00000354944.5
ENST00000537882.1
ENST00000522476.1
ENST00000518066.1
ENST00000521544.1
ENST00000518480.1
ENST00000523892.1
NDRG1
N-myc downstream regulated 1
chr1_-_27816556 0.86 ENST00000536657.1
WASF2
WAS protein family, member 2
chr2_-_10588630 0.85 ENST00000234111.4
ODC1
ornithine decarboxylase 1
chr14_+_75348592 0.85 ENST00000334220.4
DLST
dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
chr15_-_23086394 0.84 ENST00000337435.4
NIPA1
non imprinted in Prader-Willi/Angelman syndrome 1
chr10_+_72238517 0.84 ENST00000263563.6
PALD1
phosphatase domain containing, paladin 1
chr1_+_101361626 0.84 ENST00000370112.4
SLC30A7
solute carrier family 30 (zinc transporter), member 7
chr5_+_140864649 0.82 ENST00000306593.1
PCDHGC4
protocadherin gamma subfamily C, 4
chr5_+_140810132 0.76 ENST00000252085.3
PCDHGA12
protocadherin gamma subfamily A, 12
chr5_+_151151471 0.75 ENST00000394123.3
ENST00000543466.1
G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chr4_+_25235597 0.74 ENST00000264864.6
PI4K2B
phosphatidylinositol 4-kinase type 2 beta
chr5_+_140868717 0.73 ENST00000252087.1
PCDHGC5
protocadherin gamma subfamily C, 5
chr6_+_41040678 0.73 ENST00000341376.6
ENST00000353205.5
NFYA
nuclear transcription factor Y, alpha
chr9_+_118916082 0.71 ENST00000328252.3
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr5_+_140753444 0.71 ENST00000517434.1
PCDHGA6
protocadherin gamma subfamily A, 6
chr1_+_16767167 0.71 ENST00000337132.5
NECAP2
NECAP endocytosis associated 2
chr5_+_140749803 0.69 ENST00000576222.1
PCDHGB3
protocadherin gamma subfamily B, 3
chr9_-_115095883 0.69 ENST00000450374.1
ENST00000374255.2
ENST00000334318.6
ENST00000374257.1
PTBP3
polypyrimidine tract binding protein 3
chr5_+_140762268 0.68 ENST00000518325.1
PCDHGA7
protocadherin gamma subfamily A, 7
chr5_+_140743859 0.68 ENST00000518069.1
PCDHGA5
protocadherin gamma subfamily A, 5
chr5_+_140729649 0.66 ENST00000523390.1
PCDHGB1
protocadherin gamma subfamily B, 1
chr5_+_140855495 0.66 ENST00000308177.3
PCDHGC3
protocadherin gamma subfamily C, 3
chr5_+_140797296 0.65 ENST00000398594.2
PCDHGB7
protocadherin gamma subfamily B, 7
chr5_+_140772381 0.63 ENST00000398604.2
PCDHGA8
protocadherin gamma subfamily A, 8
chr5_+_140792614 0.62 ENST00000398610.2
PCDHGA10
protocadherin gamma subfamily A, 10
chr10_+_101419187 0.62 ENST00000370489.4
ENTPD7
ectonucleoside triphosphate diphosphohydrolase 7
chrX_+_41192595 0.61 ENST00000399959.2
DDX3X
DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
chr2_+_85981008 0.59 ENST00000306279.3
ATOH8
atonal homolog 8 (Drosophila)
chr22_-_17602200 0.59 ENST00000399875.1
CECR6
cat eye syndrome chromosome region, candidate 6
chr10_+_6186847 0.59 ENST00000536985.1
ENST00000379789.4
PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr5_+_140718396 0.59 ENST00000394576.2
PCDHGA2
protocadherin gamma subfamily A, 2
chr20_-_30310336 0.58 ENST00000434194.1
ENST00000376062.2
BCL2L1
BCL2-like 1
chr1_-_149900122 0.57 ENST00000271628.8
SF3B4
splicing factor 3b, subunit 4, 49kDa
chr17_+_7210294 0.57 ENST00000336452.7
EIF5A
eukaryotic translation initiation factor 5A
chr11_+_125462690 0.57 ENST00000392708.4
ENST00000529196.1
ENST00000531491.1
STT3A
STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
chr9_+_101867359 0.57 ENST00000374994.4
TGFBR1
transforming growth factor, beta receptor 1
chr21_-_15755446 0.56 ENST00000544452.1
ENST00000285667.3
HSPA13
heat shock protein 70kDa family, member 13
chr22_-_36784035 0.56 ENST00000216181.5
MYH9
myosin, heavy chain 9, non-muscle
chr17_-_79829190 0.55 ENST00000581876.1
ENST00000584461.1
ENST00000583868.1
ENST00000400721.4
ENST00000269321.7
ARHGDIA
Rho GDP dissociation inhibitor (GDI) alpha
chr22_-_42017021 0.53 ENST00000263256.6
DESI1
desumoylating isopeptidase 1
chr16_+_577697 0.52 ENST00000562370.1
ENST00000568988.1
ENST00000219611.2
CAPN15
calpain 15
chr5_+_140734570 0.51 ENST00000571252.1
PCDHGA4
protocadherin gamma subfamily A, 4
chr2_-_64881018 0.50 ENST00000313349.3
SERTAD2
SERTA domain containing 2
chr19_+_10828724 0.50 ENST00000585892.1
ENST00000314646.5
ENST00000359692.6
DNM2
dynamin 2
chr17_-_40021656 0.49 ENST00000319121.3
KLHL11
kelch-like family member 11
chr5_+_140767452 0.49 ENST00000519479.1
PCDHGB4
protocadherin gamma subfamily B, 4
chr12_-_51477333 0.49 ENST00000228515.1
ENST00000548206.1
ENST00000546935.1
ENST00000548981.1
CSRNP2
cysteine-serine-rich nuclear protein 2
chr17_+_72983674 0.49 ENST00000337231.5
CDR2L
cerebellar degeneration-related protein 2-like
chr5_+_140739537 0.48 ENST00000522605.1
PCDHGB2
protocadherin gamma subfamily B, 2
chr11_+_64009072 0.47 ENST00000535135.1
ENST00000394540.3
FKBP2
FK506 binding protein 2, 13kDa
chr14_+_74111578 0.47 ENST00000554113.1
ENST00000555631.2
ENST00000553645.2
ENST00000311089.3
ENST00000555919.3
ENST00000554339.1
ENST00000554871.1
DNAL1
dynein, axonemal, light chain 1
chr17_+_57408994 0.47 ENST00000312655.4
YPEL2
yippee-like 2 (Drosophila)
chr22_-_38669030 0.46 ENST00000361906.3
TMEM184B
transmembrane protein 184B
chr19_-_47975417 0.45 ENST00000236877.6
SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr11_+_46639071 0.44 ENST00000580238.1
ENST00000581416.1
ENST00000529655.1
ENST00000533325.1
ENST00000581438.1
ENST00000583249.1
ENST00000530500.1
ENST00000526508.1
ENST00000578626.1
ENST00000577256.1
ENST00000524625.1
ENST00000582547.1
ENST00000359513.4
ENST00000528494.1
ATG13
autophagy related 13
chr3_+_150804676 0.44 ENST00000474524.1
ENST00000273432.4
MED12L
mediator complex subunit 12-like
chr12_+_69864129 0.43 ENST00000547219.1
ENST00000299293.2
ENST00000549921.1
ENST00000550316.1
ENST00000548154.1
ENST00000547414.1
ENST00000550389.1
ENST00000550937.1
ENST00000549092.1
ENST00000550169.1
FRS2
fibroblast growth factor receptor substrate 2
chr2_+_28615669 0.43 ENST00000379619.1
ENST00000264716.4
FOSL2
FOS-like antigen 2
chr1_+_15736359 0.42 ENST00000375980.4
EFHD2
EF-hand domain family, member D2
chrX_-_48901012 0.42 ENST00000315869.7
TFE3
transcription factor binding to IGHM enhancer 3
chrX_-_153775426 0.41 ENST00000393562.2
G6PD
glucose-6-phosphate dehydrogenase
chr18_-_70210764 0.41 ENST00000585159.1
ENST00000584764.1
CBLN2
cerebellin 2 precursor
chr3_-_179169330 0.41 ENST00000232564.3
GNB4
guanine nucleotide binding protein (G protein), beta polypeptide 4
chr11_-_75062730 0.41 ENST00000420843.2
ENST00000360025.3
ARRB1
arrestin, beta 1
chr5_+_140782351 0.40 ENST00000573521.1
PCDHGA9
protocadherin gamma subfamily A, 9
chr1_-_155942086 0.40 ENST00000368315.4
ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr2_+_5832799 0.39 ENST00000322002.3
SOX11
SRY (sex determining region Y)-box 11
chr14_+_23775971 0.39 ENST00000250405.5
BCL2L2
BCL2-like 2
chr11_-_72145669 0.38 ENST00000543042.1
ENST00000294053.3
CLPB
ClpB caseinolytic peptidase B homolog (E. coli)
chrX_+_64887512 0.38 ENST00000360270.5
MSN
moesin
chr5_+_140800638 0.38 ENST00000398587.2
ENST00000518882.1
PCDHGA11
protocadherin gamma subfamily A, 11
chr12_-_121342170 0.38 ENST00000353487.2
SPPL3
signal peptide peptidase like 3
chr11_+_66610883 0.37 ENST00000309657.3
ENST00000524506.1
RCE1
Ras converting CAAX endopeptidase 1
chr1_+_110091189 0.36 ENST00000369851.4
GNAI3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr10_-_75410771 0.36 ENST00000372873.4
SYNPO2L
synaptopodin 2-like
chr1_+_45265897 0.36 ENST00000372201.4
PLK3
polo-like kinase 3
chr9_-_37465396 0.36 ENST00000307750.4
ZBTB5
zinc finger and BTB domain containing 5
chr19_+_2164126 0.35 ENST00000398665.3
DOT1L
DOT1-like histone H3K79 methyltransferase
chr6_+_33168597 0.35 ENST00000374675.3
SLC39A7
solute carrier family 39 (zinc transporter), member 7
chr12_+_56511943 0.35 ENST00000257940.2
ENST00000552345.1
ENST00000551880.1
ENST00000546903.1
ENST00000551790.1
ZC3H10
ESYT1
zinc finger CCCH-type containing 10
extended synaptotagmin-like protein 1
chr1_+_32645269 0.34 ENST00000373610.3
TXLNA
taxilin alpha
chr6_+_111195973 0.34 ENST00000368885.3
ENST00000368882.3
ENST00000451850.2
ENST00000368877.5
AMD1
adenosylmethionine decarboxylase 1
chr11_+_58346584 0.33 ENST00000316059.6
ZFP91
ZFP91 zinc finger protein
chr21_+_34697209 0.32 ENST00000270139.3
IFNAR1
interferon (alpha, beta and omega) receptor 1
chr1_+_213031570 0.32 ENST00000366971.4
FLVCR1
feline leukemia virus subgroup C cellular receptor 1
chr7_-_117513540 0.32 ENST00000160373.3
CTTNBP2
cortactin binding protein 2
chr6_+_41514078 0.32 ENST00000373063.3
ENST00000373060.1
FOXP4
forkhead box P4
chr5_+_133984462 0.32 ENST00000398844.2
ENST00000322887.4
SEC24A
SEC24 family member A
chr12_-_133405288 0.32 ENST00000204726.3
GOLGA3
golgin A3
chr19_-_663277 0.32 ENST00000292363.5
RNF126
ring finger protein 126
chr4_+_48343339 0.31 ENST00000264313.6
SLAIN2
SLAIN motif family, member 2
chr19_+_797392 0.30 ENST00000350092.4
ENST00000349038.4
ENST00000586481.1
ENST00000585535.1
PTBP1
polypyrimidine tract binding protein 1
chr19_-_17799008 0.30 ENST00000519716.2
UNC13A
unc-13 homolog A (C. elegans)
chr15_+_44719394 0.29 ENST00000260327.4
ENST00000396780.1
CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr5_-_133561752 0.29 ENST00000519718.1
ENST00000481195.1
CTD-2410N18.5
PPP2CA
S-phase kinase-associated protein 1
protein phosphatase 2, catalytic subunit, alpha isozyme
chr7_-_44924939 0.29 ENST00000395699.2
PURB
purine-rich element binding protein B
chr15_-_23034322 0.29 ENST00000539711.2
ENST00000560039.1
ENST00000398013.3
ENST00000337451.3
ENST00000359727.4
ENST00000398014.2
NIPA2
non imprinted in Prader-Willi/Angelman syndrome 2
chr1_-_201915590 0.29 ENST00000367288.4
LMOD1
leiomodin 1 (smooth muscle)
chr4_-_122854612 0.29 ENST00000264811.5
TRPC3
transient receptor potential cation channel, subfamily C, member 3
chr19_-_16682987 0.28 ENST00000431408.1
ENST00000436553.2
ENST00000595753.1
SLC35E1
solute carrier family 35, member E1
chr7_+_121513143 0.28 ENST00000393386.2
PTPRZ1
protein tyrosine phosphatase, receptor-type, Z polypeptide 1
chr10_-_5855350 0.28 ENST00000456041.1
ENST00000380181.3
ENST00000418688.1
ENST00000380132.4
ENST00000609712.1
ENST00000380191.4
GDI2
GDP dissociation inhibitor 2
chr12_-_49504655 0.28 ENST00000551782.1
ENST00000267102.8
LMBR1L
limb development membrane protein 1-like
chr14_-_23388338 0.28 ENST00000555209.1
ENST00000554256.1
ENST00000557403.1
ENST00000557549.1
ENST00000555676.1
ENST00000557571.1
ENST00000557464.1
ENST00000554618.1
ENST00000556862.1
ENST00000555722.1
ENST00000346528.5
ENST00000542016.2
ENST00000399922.2
ENST00000557227.1
ENST00000359890.3
RBM23
RNA binding motif protein 23
chr5_-_65017921 0.28 ENST00000381007.4
SGTB
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr6_+_50681541 0.28 ENST00000008391.3
TFAP2D
transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
chr20_-_44718538 0.27 ENST00000290231.6
ENST00000372291.3
NCOA5
nuclear receptor coactivator 5
chr8_-_71519889 0.27 ENST00000521425.1
TRAM1
translocation associated membrane protein 1
chr14_+_90863327 0.26 ENST00000356978.4
CALM1
calmodulin 1 (phosphorylase kinase, delta)
chr17_+_40834580 0.26 ENST00000264638.4
CNTNAP1
contactin associated protein 1
chr8_-_30670384 0.26 ENST00000221138.4
ENST00000518243.1
PPP2CB
protein phosphatase 2, catalytic subunit, beta isozyme
chr5_+_140723601 0.26 ENST00000253812.6
PCDHGA3
protocadherin gamma subfamily A, 3
chr7_+_2671568 0.25 ENST00000258796.7
TTYH3
tweety family member 3
chr19_+_15218180 0.25 ENST00000342784.2
ENST00000597977.1
ENST00000600440.1
SYDE1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr1_+_201924619 0.25 ENST00000367287.4
TIMM17A
translocase of inner mitochondrial membrane 17 homolog A (yeast)
chr12_-_113909877 0.25 ENST00000261731.3
LHX5
LIM homeobox 5
chr7_+_39989611 0.25 ENST00000181839.4
CDK13
cyclin-dependent kinase 13
chr1_+_151043070 0.24 ENST00000368918.3
ENST00000368917.1
GABPB2
GA binding protein transcription factor, beta subunit 2
chr9_+_109625378 0.24 ENST00000277225.5
ENST00000457913.1
ENST00000472574.1
ZNF462
zinc finger protein 462
chr5_+_140710061 0.24 ENST00000517417.1
ENST00000378105.3
PCDHGA1
protocadherin gamma subfamily A, 1
chr1_-_1709845 0.24 ENST00000341426.5
ENST00000344463.4
NADK
NAD kinase
chr11_-_62599505 0.24 ENST00000377897.4
ENST00000394690.1
ENST00000541317.1
ENST00000294179.3
STX5
syntaxin 5
chrX_+_95939711 0.24 ENST00000373049.4
ENST00000324765.8
DIAPH2
diaphanous-related formin 2
chr10_-_120514720 0.24 ENST00000369151.3
ENST00000340214.4
CACUL1
CDK2-associated, cullin domain 1
chr17_+_4736627 0.23 ENST00000355280.6
ENST00000347992.7
MINK1
misshapen-like kinase 1
chr1_+_162039558 0.23 ENST00000530878.1
ENST00000361897.5
NOS1AP
nitric oxide synthase 1 (neuronal) adaptor protein
chr19_+_16222439 0.23 ENST00000300935.3
RAB8A
RAB8A, member RAS oncogene family
chr1_+_154975110 0.23 ENST00000535420.1
ENST00000368426.3
ZBTB7B
zinc finger and BTB domain containing 7B
chr7_-_28220354 0.23 ENST00000283928.5
JAZF1
JAZF zinc finger 1
chr1_-_150552006 0.22 ENST00000307940.3
ENST00000369026.2
MCL1
myeloid cell leukemia sequence 1 (BCL2-related)
chr12_-_48499591 0.22 ENST00000551330.1
ENST00000004980.5
ENST00000339976.6
ENST00000448372.1
SENP1
SUMO1/sentrin specific peptidase 1
chr3_+_178276488 0.22 ENST00000432997.1
ENST00000455865.1
KCNMB2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr17_-_74733404 0.22 ENST00000508921.3
ENST00000583836.1
ENST00000358156.6
ENST00000392485.2
ENST00000359995.5
SRSF2
serine/arginine-rich splicing factor 2
chr12_-_76953284 0.21 ENST00000547544.1
ENST00000393249.2
OSBPL8
oxysterol binding protein-like 8
chr2_+_179345173 0.21 ENST00000234453.5
PLEKHA3
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3
chrX_-_129402857 0.21 ENST00000447817.1
ENST00000370978.4
ZNF280C
zinc finger protein 280C
chr16_-_58663720 0.21 ENST00000564557.1
ENST00000569240.1
ENST00000441024.2
ENST00000569020.1
ENST00000317147.5
CNOT1
CCR4-NOT transcription complex, subunit 1
chr15_+_52121822 0.20 ENST00000558455.1
ENST00000308580.7
TMOD3
tropomodulin 3 (ubiquitous)
chrX_+_14547632 0.20 ENST00000218075.4
GLRA2
glycine receptor, alpha 2
chr5_-_37839782 0.20 ENST00000326524.2
ENST00000515058.1
GDNF
glial cell derived neurotrophic factor
chr9_+_131549483 0.20 ENST00000372648.5
ENST00000539497.1
TBC1D13
TBC1 domain family, member 13
chr6_-_90121938 0.19 ENST00000369415.4
RRAGD
Ras-related GTP binding D
chr12_+_70132632 0.19 ENST00000378815.6
ENST00000483530.2
ENST00000325555.9
RAB3IP
RAB3A interacting protein
chr19_+_8429031 0.19 ENST00000301455.2
ENST00000541807.1
ENST00000393962.2
ANGPTL4
angiopoietin-like 4
chr1_-_150947343 0.19 ENST00000271688.6
ENST00000368954.5
CERS2
ceramide synthase 2
chr2_-_40679186 0.19 ENST00000406785.2
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr7_+_157129660 0.18 ENST00000429029.2
ENST00000262177.4
ENST00000417758.1
ENST00000452797.2
ENST00000443280.1
DNAJB6
DnaJ (Hsp40) homolog, subfamily B, member 6
chr19_+_49660997 0.18 ENST00000598691.1
ENST00000252826.5
TRPM4
transient receptor potential cation channel, subfamily M, member 4
chr19_-_8070474 0.18 ENST00000407627.2
ENST00000593807.1
ELAVL1
ELAV like RNA binding protein 1
chr4_+_111397216 0.17 ENST00000265162.5
ENPEP
glutamyl aminopeptidase (aminopeptidase A)
chr5_-_130970723 0.17 ENST00000308008.6
ENST00000296859.6
ENST00000507093.1
ENST00000510071.1
ENST00000509018.1
ENST00000307984.5
RAPGEF6
Rap guanine nucleotide exchange factor (GEF) 6
chr4_+_93225550 0.17 ENST00000282020.4
GRID2
glutamate receptor, ionotropic, delta 2
chr17_+_37026106 0.17 ENST00000318008.6
LASP1
LIM and SH3 protein 1
chr2_-_174830430 0.17 ENST00000310015.6
ENST00000455789.2
SP3
Sp3 transcription factor
chr22_+_29469012 0.17 ENST00000400335.4
ENST00000400338.2
KREMEN1
kringle containing transmembrane protein 1
chr1_+_203764742 0.17 ENST00000432282.1
ENST00000453771.1
ENST00000367214.1
ENST00000367212.3
ENST00000332127.4
ZC3H11A
zinc finger CCCH-type containing 11A
chr19_-_4400415 0.17 ENST00000598564.1
ENST00000417295.2
ENST00000269886.3
SH3GL1
SH3-domain GRB2-like 1
chr1_+_33116743 0.17 ENST00000414241.3
ENST00000373493.5
RBBP4
retinoblastoma binding protein 4
chr12_-_54779511 0.17 ENST00000551109.1
ENST00000546970.1
ZNF385A
zinc finger protein 385A
chr1_+_22379120 0.17 ENST00000400259.1
ENST00000344548.3
CDC42
cell division cycle 42
chr12_-_117175819 0.16 ENST00000261318.3
ENST00000536380.1
C12orf49
chromosome 12 open reading frame 49
chr5_-_16509101 0.16 ENST00000399793.2
FAM134B
family with sequence similarity 134, member B
chrX_-_108976521 0.15 ENST00000469796.2
ENST00000502391.1
ENST00000508092.1
ENST00000340800.2
ENST00000348502.6
ACSL4
acyl-CoA synthetase long-chain family member 4
chr17_-_5389477 0.15 ENST00000572834.1
ENST00000570848.1
ENST00000571971.1
ENST00000158771.4
DERL2
derlin 2
chr12_-_57030115 0.15 ENST00000379441.3
ENST00000179765.5
ENST00000551812.1
BAZ2A
bromodomain adjacent to zinc finger domain, 2A
chr3_-_49823941 0.15 ENST00000321599.4
ENST00000395238.1
ENST00000468463.1
ENST00000460540.1
IP6K1
inositol hexakisphosphate kinase 1
chr11_-_9025541 0.15 ENST00000525100.1
ENST00000309166.3
ENST00000531090.1
NRIP3
nuclear receptor interacting protein 3
chr16_+_5008290 0.15 ENST00000251170.7
SEC14L5
SEC14-like 5 (S. cerevisiae)
chr12_+_27932803 0.15 ENST00000381271.2
KLHL42
kelch-like family member 42
chr11_-_6502534 0.15 ENST00000254584.2
ENST00000525235.1
ENST00000445086.2
ARFIP2
ADP-ribosylation factor interacting protein 2
chr20_+_36149602 0.14 ENST00000062104.2
ENST00000346199.2
NNAT
neuronatin
chr9_+_131843377 0.14 ENST00000372546.4
ENST00000406974.3
ENST00000540102.1
DOLPP1
dolichyldiphosphatase 1
chr1_+_218458625 0.14 ENST00000366932.3
RRP15
ribosomal RNA processing 15 homolog (S. cerevisiae)
chr12_-_82153087 0.14 ENST00000547623.1
ENST00000549396.1
PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chrY_+_15016725 0.14 ENST00000336079.3
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr1_-_201390846 0.14 ENST00000367312.1
ENST00000555340.2
ENST00000361379.4
TNNI1
troponin I type 1 (skeletal, slow)
chr7_+_55433131 0.13 ENST00000254770.2
LANCL2
LanC lantibiotic synthetase component C-like 2 (bacterial)
chr2_-_232645977 0.13 ENST00000409772.1
PDE6D
phosphodiesterase 6D, cGMP-specific, rod, delta
chr19_+_16187085 0.13 ENST00000300933.4
TPM4
tropomyosin 4
chr1_+_47799446 0.13 ENST00000371873.5
CMPK1
cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
chr3_+_11034403 0.13 ENST00000287766.4
ENST00000425938.1
SLC6A1
solute carrier family 6 (neurotransmitter transporter), member 1
chr17_+_26989109 0.13 ENST00000314616.6
ENST00000347486.4
SUPT6H
suppressor of Ty 6 homolog (S. cerevisiae)
chr17_-_3599327 0.12 ENST00000551178.1
ENST00000552276.1
ENST00000547178.1
P2RX5
purinergic receptor P2X, ligand-gated ion channel, 5
chr1_-_89458415 0.12 ENST00000321792.5
ENST00000370491.3
RBMXL1
CCBL2
RNA binding motif protein, X-linked-like 1
cysteine conjugate-beta lyase 2
chr7_-_141401951 0.12 ENST00000536163.1
KIAA1147
KIAA1147

Network of associatons between targets according to the STRING database.

First level regulatory network of UGGUCCC

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:1990108 protein linear deubiquitination(GO:1990108)
0.5 1.9 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.4 1.5 GO:0003409 optic cup structural organization(GO:0003409)
0.4 1.1 GO:1901656 glycoside transport(GO:1901656)
0.3 1.2 GO:0046035 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.2 0.8 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.2 0.6 GO:0043686 co-translational protein modification(GO:0043686)
0.2 1.7 GO:0070294 renal sodium ion absorption(GO:0070294)
0.2 1.3 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.2 0.5 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.2 0.5 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.1 0.4 GO:0061386 closure of optic fissure(GO:0061386)
0.1 0.4 GO:0007113 endomitotic cell cycle(GO:0007113) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.1 0.6 GO:0003343 proepicardium development(GO:0003342) septum transversum development(GO:0003343) occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.1 0.3 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.4 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.1 0.6 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.6 GO:1903923 protein processing in phagocytic vesicle(GO:1900756) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923)
0.1 0.4 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.1 1.0 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.8 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.1 0.9 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.1 0.4 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.1 0.2 GO:1903762 positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903762) positive regulation of ventricular cardiac muscle cell action potential(GO:1903947) positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905026) positive regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905033)
0.1 1.1 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.5 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.1 0.6 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.1 0.6 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.3 GO:0070445 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.1 0.4 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1 0.2 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.1 11.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.2 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.1 1.1 GO:0008228 opsonization(GO:0008228)
0.1 0.2 GO:0071338 submandibular salivary gland formation(GO:0060661) hair follicle cell proliferation(GO:0071335) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.1 0.4 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.1 0.4 GO:0022614 membrane to membrane docking(GO:0022614)
0.1 0.9 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.1 0.1 GO:0003162 atrioventricular node development(GO:0003162)
0.1 0.8 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.5 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.3 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.0 0.3 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.2 GO:1990736 positive regulation of atrial cardiac muscle cell action potential(GO:1903949) positive regulation of regulation of vascular smooth muscle cell membrane depolarization(GO:1904199) regulation of vascular smooth muscle cell membrane depolarization(GO:1990736)
0.0 0.4 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.3 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.2 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.0 1.0 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.2 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.0 0.2 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.0 0.2 GO:0021707 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) positive regulation of long term synaptic depression(GO:1900454)
0.0 0.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.2 GO:0090166 Golgi disassembly(GO:0090166)
0.0 0.2 GO:0021784 postganglionic parasympathetic fiber development(GO:0021784)
0.0 0.1 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.0 0.1 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.0 0.3 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.6 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.0 0.7 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 0.2 GO:0060318 regulation of definitive erythrocyte differentiation(GO:0010724) definitive erythrocyte differentiation(GO:0060318)
0.0 0.3 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.6 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.1 GO:0032900 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) negative regulation of neurotrophin production(GO:0032900) negative regulation of transforming growth factor beta1 production(GO:0032911)
0.0 0.2 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.0 0.1 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 0.2 GO:0044266 angiotensin catabolic process in blood(GO:0002005) multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266)
0.0 0.2 GO:0071233 cellular response to leucine(GO:0071233)
0.0 0.1 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.5 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.1 GO:1901419 regulation of response to alcohol(GO:1901419)
0.0 0.2 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.4 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.3 GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.0 0.2 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.2 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.1 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0 1.1 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.6 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.3 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.2 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.2 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:0006489 dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.0 0.6 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 0.4 GO:0030033 microvillus assembly(GO:0030033)
0.0 0.2 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.1 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.4 GO:0098780 response to mitochondrial depolarisation(GO:0098780)
0.0 0.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.0 0.2 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.0 0.1 GO:0033686 oocyte growth(GO:0001555) positive regulation of luteinizing hormone secretion(GO:0033686)
0.0 0.4 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.1 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.2 GO:0033197 response to vitamin E(GO:0033197)
0.0 0.2 GO:1903540 neurotransmitter receptor transport to postsynaptic membrane(GO:0098969) establishment of protein localization to postsynaptic membrane(GO:1903540)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.7 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.0 0.1 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.1 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.0 0.2 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 1.5 GO:0030193 regulation of blood coagulation(GO:0030193) regulation of hemostasis(GO:1900046)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0097513 actomyosin contractile ring(GO:0005826) myosin II filament(GO:0097513)
0.1 0.3 GO:0072534 perineuronal net(GO:0072534)
0.1 1.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.2 GO:0002945 cyclin K-CDK13 complex(GO:0002945)
0.1 0.8 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 0.4 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.1 0.7 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.3 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.1 0.6 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.3 GO:0044305 calyx of Held(GO:0044305)
0.1 0.9 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.2 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.5 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.2 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.2 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.6 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.8 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.6 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.4 GO:0042588 zymogen granule(GO:0042588)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.2 GO:0000322 storage vacuole(GO:0000322)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 2.0 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.5 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.6 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.2 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.3 GO:0033010 paranodal junction(GO:0033010)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.8 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.3 GO:0035371 microtubule plus-end(GO:0035371)
0.0 1.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.7 GO:0010494 cytoplasmic stress granule(GO:0010494)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0016748 succinyltransferase activity(GO:0016748)
0.1 1.0 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.1 0.4 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 0.4 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.1 1.6 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 1.3 GO:0004849 uridine kinase activity(GO:0004849)
0.1 1.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 0.3 GO:0019961 interferon binding(GO:0019961)
0.1 0.7 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.5 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.1 0.6 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1 0.1 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.1 0.8 GO:0051434 BH3 domain binding(GO:0051434)
0.1 1.7 GO:0017081 chloride channel regulator activity(GO:0017081)
0.1 0.6 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.4 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 1.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.2 GO:0032427 GBD domain binding(GO:0032427)
0.1 0.6 GO:0033592 RNA strand annealing activity(GO:0033592)
0.1 0.6 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.9 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.6 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.3 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.4 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.2 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.6 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.4 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0052839 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 1.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.6 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.4 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.3 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.2 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.1 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.5 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.9 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 1.2 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.3 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.7 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 2.1 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.8 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 1.0 GO:1901505 carbohydrate derivative transporter activity(GO:1901505)
0.0 0.5 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.5 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.2 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.1 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.1 GO:0042835 BRE binding(GO:0042835)
0.0 0.1 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.3 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.6 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 1.0 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.5 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 1.5 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.7 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.6 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.3 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 1.7 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 1.1 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.9 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.8 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.4 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.3 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.4 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.4 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.9 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 1.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.6 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.8 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 1.6 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.9 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.8 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.9 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.6 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.4 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.8 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.5 REACTOME PROLONGED ERK ACTIVATION EVENTS Genes involved in Prolonged ERK activation events
0.0 0.6 REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.0 0.7 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.7 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.0 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.8 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.3 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling