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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for UUGGCAA

Z-value: 0.43

Motif logo

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miRNA associated with seed UUGGCAA

NamemiRBASE accession
hsa-miR-182-5p
MIMAT0000259

Activity profile of UUGGCAA motif

Sorted Z-values of UUGGCAA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_131762105 2.01 ENST00000368648.3
ENST00000355311.5
EBF3
early B-cell factor 3
chr9_+_79074068 1.41 ENST00000444201.2
ENST00000376730.4
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2
chr9_-_134145880 1.33 ENST00000372269.3
ENST00000464831.1
FAM78A
family with sequence similarity 78, member A
chr8_-_22550815 1.31 ENST00000317216.2
EGR3
early growth response 3
chr3_+_39851094 1.28 ENST00000302541.6
MYRIP
myosin VIIA and Rab interacting protein
chr1_+_84543734 1.24 ENST00000370689.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr3_+_193853927 1.08 ENST00000232424.3
HES1
hes family bHLH transcription factor 1
chrX_+_101967257 1.02 ENST00000543253.1
ENST00000535209.1
GPRASP2
G protein-coupled receptor associated sorting protein 2
chr20_+_42544782 0.96 ENST00000423191.2
ENST00000372999.1
TOX2
TOX high mobility group box family member 2
chr9_+_115513003 0.92 ENST00000374232.3
SNX30
sorting nexin family member 30
chr6_+_136172820 0.87 ENST00000308191.6
PDE7B
phosphodiesterase 7B
chr1_+_65210772 0.87 ENST00000371072.4
ENST00000294428.3
RAVER2
ribonucleoprotein, PTB-binding 2
chr4_+_134070439 0.85 ENST00000264360.5
PCDH10
protocadherin 10
chr1_+_76540386 0.83 ENST00000328299.3
ST6GALNAC3
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr9_+_4490394 0.83 ENST00000262352.3
SLC1A1
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr4_-_102268628 0.82 ENST00000323055.6
ENST00000512215.1
ENST00000394854.3
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr7_+_17338239 0.78 ENST00000242057.4
AHR
aryl hydrocarbon receptor
chr4_+_41362796 0.77 ENST00000508501.1
ENST00000512946.1
ENST00000313860.7
ENST00000512632.1
ENST00000512820.1
LIMCH1
LIM and calponin homology domains 1
chr17_+_47865917 0.74 ENST00000259021.4
ENST00000454930.2
ENST00000509773.1
ENST00000510819.1
ENST00000424009.2
KAT7
K(lysine) acetyltransferase 7
chr13_+_50656307 0.74 ENST00000378180.4
DLEU1
deleted in lymphocytic leukemia 1 (non-protein coding)
chr8_+_37654424 0.74 ENST00000315215.7
GPR124
G protein-coupled receptor 124
chr8_-_81083731 0.72 ENST00000379096.5
TPD52
tumor protein D52
chr5_-_90679145 0.71 ENST00000265138.3
ARRDC3
arrestin domain containing 3
chr12_-_56727487 0.70 ENST00000548043.1
ENST00000425394.2
PAN2
PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr2_+_45878790 0.69 ENST00000306156.3
PRKCE
protein kinase C, epsilon
chr1_+_25870070 0.69 ENST00000374338.4
LDLRAP1
low density lipoprotein receptor adaptor protein 1
chr1_-_209979375 0.65 ENST00000367021.3
IRF6
interferon regulatory factor 6
chr5_-_172198190 0.65 ENST00000239223.3
DUSP1
dual specificity phosphatase 1
chr14_-_30396948 0.64 ENST00000331968.5
PRKD1
protein kinase D1
chr12_-_96184533 0.62 ENST00000343702.4
ENST00000344911.4
NTN4
netrin 4
chr9_-_80646374 0.58 ENST00000286548.4
GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
chr6_+_18387570 0.58 ENST00000259939.3
RNF144B
ring finger protein 144B
chr5_-_107006596 0.58 ENST00000333274.6
EFNA5
ephrin-A5
chr6_+_17600576 0.57 ENST00000259963.3
FAM8A1
family with sequence similarity 8, member A1
chr19_+_32896697 0.55 ENST00000586987.1
DPY19L3
dpy-19-like 3 (C. elegans)
chr14_-_90085458 0.54 ENST00000345097.4
ENST00000555855.1
ENST00000555353.1
FOXN3
forkhead box N3
chr2_-_43453734 0.53 ENST00000282388.3
ZFP36L2
ZFP36 ring finger protein-like 2
chr6_-_41909561 0.52 ENST00000372991.4
CCND3
cyclin D3
chr1_-_20812690 0.52 ENST00000375078.3
CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr3_-_32022733 0.52 ENST00000438237.2
ENST00000396556.2
OSBPL10
oxysterol binding protein-like 10
chr6_-_16761678 0.52 ENST00000244769.4
ENST00000436367.1
ATXN1
ataxin 1
chr11_-_94964354 0.50 ENST00000536441.1
SESN3
sestrin 3
chr1_+_82266053 0.50 ENST00000370715.1
ENST00000370713.1
ENST00000319517.6
ENST00000370717.2
ENST00000394879.1
ENST00000271029.4
ENST00000335786.5
LPHN2
latrophilin 2
chr9_+_36036430 0.50 ENST00000377966.3
RECK
reversion-inducing-cysteine-rich protein with kazal motifs
chr13_-_107187462 0.49 ENST00000245323.4
EFNB2
ephrin-B2
chr18_-_72921303 0.49 ENST00000322342.3
ZADH2
zinc binding alcohol dehydrogenase domain containing 2
chr1_+_178694300 0.48 ENST00000367635.3
RALGPS2
Ral GEF with PH domain and SH3 binding motif 2
chr8_-_124286735 0.48 ENST00000395571.3
ZHX1
zinc fingers and homeoboxes 1
chr2_+_46524537 0.47 ENST00000263734.3
EPAS1
endothelial PAS domain protein 1
chr4_+_145567173 0.47 ENST00000296575.3
HHIP
hedgehog interacting protein
chr11_+_92085262 0.47 ENST00000298047.6
ENST00000409404.2
ENST00000541502.1
FAT3
FAT atypical cadherin 3
chr13_+_39612442 0.47 ENST00000470258.1
ENST00000379600.3
NHLRC3
NHL repeat containing 3
chr6_-_99395787 0.46 ENST00000369244.2
ENST00000229971.1
FBXL4
F-box and leucine-rich repeat protein 4
chr2_+_109204909 0.46 ENST00000393310.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr3_+_8543393 0.46 ENST00000157600.3
ENST00000415597.1
ENST00000535732.1
LMCD1
LIM and cysteine-rich domains 1
chr8_-_81787006 0.45 ENST00000327835.3
ZNF704
zinc finger protein 704
chr6_-_32157947 0.45 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr6_-_79787902 0.45 ENST00000275034.4
PHIP
pleckstrin homology domain interacting protein
chr12_+_3186521 0.45 ENST00000537971.1
ENST00000011898.5
TSPAN9
tetraspanin 9
chr7_-_86688990 0.44 ENST00000450689.2
KIAA1324L
KIAA1324-like
chr1_-_16678914 0.44 ENST00000375592.3
FBXO42
F-box protein 42
chr8_-_89339705 0.44 ENST00000286614.6
MMP16
matrix metallopeptidase 16 (membrane-inserted)
chr17_-_48943706 0.43 ENST00000499247.2
TOB1
transducer of ERBB2, 1
chr2_+_173600671 0.43 ENST00000409036.1
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr11_-_73309228 0.42 ENST00000356467.4
ENST00000064778.4
FAM168A
family with sequence similarity 168, member A
chr1_-_211752073 0.42 ENST00000367001.4
SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr14_+_57735614 0.41 ENST00000261558.3
AP5M1
adaptor-related protein complex 5, mu 1 subunit
chr4_-_138453606 0.41 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
PCDH18
protocadherin 18
chr4_-_89744457 0.41 ENST00000395002.2
FAM13A
family with sequence similarity 13, member A
chr10_-_52383644 0.39 ENST00000361781.2
SGMS1
sphingomyelin synthase 1
chr11_-_64570706 0.39 ENST00000294066.2
ENST00000377350.3
MAP4K2
mitogen-activated protein kinase kinase kinase kinase 2
chr9_-_111882195 0.39 ENST00000374586.3
TMEM245
transmembrane protein 245
chr11_+_7597639 0.38 ENST00000533792.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr14_+_63671105 0.38 ENST00000316754.3
RHOJ
ras homolog family member J
chr2_-_44588893 0.38 ENST00000409272.1
ENST00000410081.1
ENST00000541738.1
PREPL
prolyl endopeptidase-like
chr17_-_57970074 0.38 ENST00000346141.6
TUBD1
tubulin, delta 1
chr12_+_32655048 0.37 ENST00000427716.2
ENST00000266482.3
FGD4
FYVE, RhoGEF and PH domain containing 4
chr11_+_12695944 0.36 ENST00000361905.4
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr9_+_91003271 0.35 ENST00000375859.3
ENST00000541629.1
SPIN1
spindlin 1
chr2_+_235860616 0.35 ENST00000392011.2
SH3BP4
SH3-domain binding protein 4
chr11_+_134094508 0.35 ENST00000281187.5
ENST00000525095.2
VPS26B
vacuolar protein sorting 26 homolog B (S. pombe)
chr12_+_56521840 0.34 ENST00000394048.5
ESYT1
extended synaptotagmin-like protein 1
chr10_-_116286656 0.34 ENST00000428430.1
ENST00000369266.3
ENST00000392952.3
ABLIM1
actin binding LIM protein 1
chrX_-_154033793 0.33 ENST00000369534.3
ENST00000413259.3
MPP1
membrane protein, palmitoylated 1, 55kDa
chr9_-_16870704 0.33 ENST00000380672.4
ENST00000380667.2
ENST00000380666.2
ENST00000486514.1
BNC2
basonuclin 2
chr3_-_171527560 0.33 ENST00000331659.2
PP13439
PP13439
chr1_+_231664390 0.32 ENST00000366639.4
ENST00000413309.2
TSNAX
translin-associated factor X
chr19_-_10341948 0.32 ENST00000590320.1
ENST00000592342.1
ENST00000588952.1
S1PR2
DNMT1
sphingosine-1-phosphate receptor 2
DNA (cytosine-5-)-methyltransferase 1
chr10_+_35535943 0.31 ENST00000490012.2
ENST00000374706.1
ENST00000493157.2
CCNY
cyclin Y
chrX_-_114468605 0.31 ENST00000538422.1
ENST00000317135.8
LRCH2
leucine-rich repeats and calponin homology (CH) domain containing 2
chr22_-_36903101 0.31 ENST00000397224.4
FOXRED2
FAD-dependent oxidoreductase domain containing 2
chr12_-_58027138 0.30 ENST00000341156.4
B4GALNT1
beta-1,4-N-acetyl-galactosaminyl transferase 1
chr4_-_42659102 0.30 ENST00000264449.10
ENST00000510289.1
ENST00000381668.5
ATP8A1
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
chr1_+_201798269 0.30 ENST00000361565.4
IPO9
importin 9
chr8_+_28351707 0.30 ENST00000537916.1
ENST00000523546.1
ENST00000240093.3
FZD3
frizzled family receptor 3
chr11_+_123396528 0.30 ENST00000322282.7
ENST00000529750.1
GRAMD1B
GRAM domain containing 1B
chr19_-_33555780 0.29 ENST00000254260.3
ENST00000400226.4
RHPN2
rhophilin, Rho GTPase binding protein 2
chr12_-_31744031 0.29 ENST00000389082.5
DENND5B
DENN/MADD domain containing 5B
chr13_-_20735178 0.29 ENST00000241125.3
GJA3
gap junction protein, alpha 3, 46kDa
chr5_+_57878859 0.29 ENST00000282878.4
RAB3C
RAB3C, member RAS oncogene family
chr9_-_4741255 0.29 ENST00000381809.3
AK3
adenylate kinase 3
chr9_+_95087766 0.29 ENST00000375587.3
CENPP
centromere protein P
chr2_+_113033164 0.29 ENST00000409871.1
ENST00000343936.4
ZC3H6
zinc finger CCCH-type containing 6
chr7_-_130080977 0.29 ENST00000223208.5
CEP41
centrosomal protein 41kDa
chr3_+_138066539 0.29 ENST00000289104.4
MRAS
muscle RAS oncogene homolog
chr17_+_65821780 0.28 ENST00000321892.4
ENST00000335221.5
ENST00000306378.6
BPTF
bromodomain PHD finger transcription factor
chr21_-_44846999 0.28 ENST00000270162.6
SIK1
salt-inducible kinase 1
chr14_-_39901618 0.28 ENST00000554932.1
ENST00000298097.7
FBXO33
F-box protein 33
chr5_-_89770582 0.27 ENST00000316610.6
MBLAC2
metallo-beta-lactamase domain containing 2
chr1_+_93913713 0.27 ENST00000604705.1
ENST00000370253.2
FNBP1L
formin binding protein 1-like
chr1_+_90098606 0.26 ENST00000370454.4
LRRC8C
leucine rich repeat containing 8 family, member C
chr13_-_41240717 0.26 ENST00000379561.5
FOXO1
forkhead box O1
chr22_+_19744226 0.26 ENST00000332710.4
ENST00000329705.7
ENST00000359500.3
TBX1
T-box 1
chr9_+_2621798 0.26 ENST00000382100.3
VLDLR
very low density lipoprotein receptor
chr11_-_8680383 0.26 ENST00000299550.6
TRIM66
tripartite motif containing 66
chr2_+_219264466 0.26 ENST00000273062.2
CTDSP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr9_-_116061476 0.26 ENST00000441031.3
RNF183
ring finger protein 183
chr20_-_60640866 0.25 ENST00000252996.4
TAF4
TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
chr4_-_78740511 0.25 ENST00000504123.1
ENST00000264903.4
ENST00000515441.1
CNOT6L
CCR4-NOT transcription complex, subunit 6-like
chr2_-_218808771 0.25 ENST00000449814.1
ENST00000171887.4
TNS1
tensin 1
chr1_+_185703513 0.25 ENST00000271588.4
ENST00000367492.2
HMCN1
hemicentin 1
chr7_+_142985308 0.25 ENST00000310447.5
CASP2
caspase 2, apoptosis-related cysteine peptidase
chr1_+_200708671 0.25 ENST00000358823.2
CAMSAP2
calmodulin regulated spectrin-associated protein family, member 2
chr17_+_73043301 0.24 ENST00000322444.6
KCTD2
potassium channel tetramerization domain containing 2
chr12_-_42538657 0.24 ENST00000398675.3
GXYLT1
glucoside xylosyltransferase 1
chr12_-_109125285 0.24 ENST00000552871.1
ENST00000261401.3
CORO1C
coronin, actin binding protein, 1C
chr15_+_52043758 0.24 ENST00000249700.4
ENST00000539962.2
TMOD2
tropomodulin 2 (neuronal)
chr8_-_93978357 0.24 ENST00000522925.1
ENST00000522903.1
ENST00000537541.1
ENST00000518748.1
ENST00000519069.1
ENST00000521988.1
TRIQK
triple QxxK/R motif containing
chr10_-_16859361 0.24 ENST00000377921.3
RSU1
Ras suppressor protein 1
chr3_+_15247686 0.24 ENST00000253693.2
CAPN7
calpain 7
chr1_-_154934200 0.23 ENST00000368457.2
PYGO2
pygopus family PHD finger 2
chr1_+_77747656 0.23 ENST00000354567.2
AK5
adenylate kinase 5
chrX_-_117250740 0.23 ENST00000371882.1
ENST00000540167.1
ENST00000545703.1
KLHL13
kelch-like family member 13
chr8_-_66754172 0.23 ENST00000401827.3
PDE7A
phosphodiesterase 7A
chr10_-_65225722 0.22 ENST00000399251.1
JMJD1C
jumonji domain containing 1C
chr7_-_27205136 0.22 ENST00000396345.1
ENST00000343483.6
HOXA9
homeobox A9
chr3_+_57261743 0.22 ENST00000288266.3
APPL1
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
chr16_+_77822427 0.22 ENST00000302536.2
VAT1L
vesicle amine transport 1-like
chr1_+_113615794 0.22 ENST00000361127.5
LRIG2
leucine-rich repeats and immunoglobulin-like domains 2
chr14_-_77495007 0.22 ENST00000238647.3
IRF2BPL
interferon regulatory factor 2 binding protein-like
chr21_-_34852304 0.22 ENST00000542230.2
TMEM50B
transmembrane protein 50B
chr10_-_62704005 0.22 ENST00000337910.5
RHOBTB1
Rho-related BTB domain containing 1
chr3_-_126076264 0.22 ENST00000296233.3
KLF15
Kruppel-like factor 15
chr16_-_57513657 0.21 ENST00000566936.1
ENST00000568617.1
ENST00000567276.1
ENST00000569548.1
ENST00000569250.1
ENST00000564378.1
DOK4
docking protein 4
chr2_-_183903133 0.21 ENST00000361354.4
NCKAP1
NCK-associated protein 1
chr11_+_120207787 0.21 ENST00000397843.2
ENST00000356641.3
ARHGEF12
Rho guanine nucleotide exchange factor (GEF) 12
chr17_+_61699766 0.20 ENST00000579585.1
ENST00000584573.1
ENST00000361733.3
ENST00000361357.3
MAP3K3
mitogen-activated protein kinase kinase kinase 3
chr1_-_211666259 0.20 ENST00000367002.4
RD3
retinal degeneration 3
chr6_+_88182643 0.20 ENST00000369556.3
ENST00000544441.1
ENST00000369552.4
ENST00000369557.5
SLC35A1
solute carrier family 35 (CMP-sialic acid transporter), member A1
chr21_-_40685477 0.20 ENST00000342449.3
BRWD1
bromodomain and WD repeat domain containing 1
chr18_+_47088401 0.20 ENST00000261292.4
ENST00000427224.2
ENST00000580036.1
LIPG
lipase, endothelial
chr1_-_109940550 0.20 ENST00000256637.6
SORT1
sortilin 1
chr7_-_134001663 0.20 ENST00000378509.4
SLC35B4
solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4
chr1_+_180601139 0.20 ENST00000367590.4
ENST00000367589.3
XPR1
xenotropic and polytropic retrovirus receptor 1
chr12_+_57943781 0.20 ENST00000455537.2
ENST00000286452.5
KIF5A
kinesin family member 5A
chr3_+_134514093 0.20 ENST00000398015.3
EPHB1
EPH receptor B1
chr2_-_100106419 0.20 ENST00000393445.3
ENST00000258428.3
REV1
REV1, polymerase (DNA directed)
chr8_-_60031762 0.20 ENST00000361421.1
TOX
thymocyte selection-associated high mobility group box
chr21_-_39870339 0.19 ENST00000429727.2
ENST00000398905.1
ENST00000398907.1
ENST00000453032.2
ENST00000288319.7
ERG
v-ets avian erythroblastosis virus E26 oncogene homolog
chr5_+_86564739 0.19 ENST00000456692.2
ENST00000512763.1
ENST00000506290.1
RASA1
RAS p21 protein activator (GTPase activating protein) 1
chr4_+_71768043 0.19 ENST00000502869.1
ENST00000309395.2
ENST00000396051.2
MOB1B
MOB kinase activator 1B
chr19_-_6279932 0.19 ENST00000252674.7
MLLT1
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
chr1_-_109584608 0.19 ENST00000400794.3
ENST00000528747.1
ENST00000369962.3
ENST00000361054.3
WDR47
WD repeat domain 47
chr3_+_179370517 0.19 ENST00000263966.3
USP13
ubiquitin specific peptidase 13 (isopeptidase T-3)
chr1_-_44497024 0.19 ENST00000372306.3
ENST00000372310.3
ENST00000475075.2
SLC6A9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr1_-_53018654 0.19 ENST00000257177.4
ENST00000355809.4
ENST00000528642.1
ENST00000470626.1
ENST00000371544.3
ZCCHC11
zinc finger, CCHC domain containing 11
chr2_-_197036289 0.19 ENST00000263955.4
STK17B
serine/threonine kinase 17b
chr1_-_55352834 0.19 ENST00000371269.3
DHCR24
24-dehydrocholesterol reductase
chr13_+_28813645 0.18 ENST00000282391.5
PAN3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr20_+_277737 0.18 ENST00000382352.3
ZCCHC3
zinc finger, CCHC domain containing 3
chr5_-_162887071 0.18 ENST00000302764.4
NUDCD2
NudC domain containing 2
chr2_-_151344172 0.18 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
RND3
Rho family GTPase 3
chr7_+_94139105 0.18 ENST00000297273.4
CASD1
CAS1 domain containing 1
chr18_-_54305658 0.18 ENST00000586262.1
ENST00000217515.6
TXNL1
thioredoxin-like 1
chr1_+_220960033 0.18 ENST00000366910.5
MARC1
mitochondrial amidoxime reducing component 1
chr2_+_198669365 0.18 ENST00000428675.1
PLCL1
phospholipase C-like 1
chr12_+_14518598 0.18 ENST00000261168.4
ENST00000538511.1
ENST00000545723.1
ENST00000543189.1
ENST00000536444.1
ATF7IP
activating transcription factor 7 interacting protein
chr9_-_140115775 0.18 ENST00000391553.1
ENST00000392827.1
RNF208
ring finger protein 208
chr19_-_45908292 0.18 ENST00000360957.5
ENST00000592134.1
PPP1R13L
protein phosphatase 1, regulatory subunit 13 like
chr6_-_30710510 0.18 ENST00000376389.3
FLOT1
flotillin 1
chr2_+_121010324 0.18 ENST00000272519.5
RALB
v-ral simian leukemia viral oncogene homolog B
chr17_+_67410832 0.18 ENST00000590474.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr4_-_16228120 0.18 ENST00000405303.2
TAPT1
transmembrane anterior posterior transformation 1
chr8_-_52811640 0.18 ENST00000360540.5
ENST00000521344.1
PCMTD1
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
chr8_-_95961578 0.17 ENST00000448464.2
ENST00000342697.4
TP53INP1
tumor protein p53 inducible nuclear protein 1
chr22_-_39548627 0.17 ENST00000216133.5
CBX7
chromobox homolog 7
chr14_+_56046914 0.17 ENST00000413890.2
ENST00000395309.3
ENST00000554567.1
ENST00000555498.1
KTN1
kinectin 1 (kinesin receptor)
chr5_-_179499086 0.17 ENST00000261947.4
RNF130
ring finger protein 130
chr9_-_79520989 0.17 ENST00000376713.3
ENST00000376718.3
ENST00000428286.1
PRUNE2
prune homolog 2 (Drosophila)
chr5_+_118407053 0.17 ENST00000311085.8
ENST00000539542.1
DMXL1
Dmx-like 1
chr2_+_32288725 0.17 ENST00000315285.3
SPAST
spastin
chr12_+_32260085 0.17 ENST00000548411.1
ENST00000281474.5
ENST00000551086.1
BICD1
bicaudal D homolog 1 (Drosophila)
chr2_+_120517174 0.17 ENST00000263708.2
PTPN4
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chrX_-_34675391 0.16 ENST00000275954.3
TMEM47
transmembrane protein 47
chr6_-_139695757 0.16 ENST00000367651.2
CITED2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr10_-_13390270 0.16 ENST00000378614.4
ENST00000545675.1
ENST00000327347.5
SEPHS1
selenophosphate synthetase 1
chr5_+_176560742 0.16 ENST00000439151.2
NSD1
nuclear receptor binding SET domain protein 1
chr5_+_138678131 0.15 ENST00000394795.2
ENST00000510080.1
PAIP2
poly(A) binding protein interacting protein 2
chr2_+_241375069 0.15 ENST00000264039.2
GPC1
glypican 1
chrX_+_16964794 0.15 ENST00000357277.3
REPS2
RALBP1 associated Eps domain containing 2

Network of associatons between targets according to the STRING database.

First level regulatory network of UUGGCAA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0060164 trochlear nerve development(GO:0021558) auditory receptor cell fate determination(GO:0042668) negative regulation of auditory receptor cell differentiation(GO:0045608) regulation of timing of neuron differentiation(GO:0060164) negative regulation of pro-B cell differentiation(GO:2000974)
0.3 0.8 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.2 0.7 GO:0072720 response to dithiothreitol(GO:0072720)
0.2 0.7 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.2 0.7 GO:0035669 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.2 1.2 GO:0097338 response to clozapine(GO:0097338)
0.2 0.7 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.2 1.3 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.1 1.6 GO:0060352 cell adhesion molecule production(GO:0060352)
0.1 0.5 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.1 0.6 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 0.8 GO:0000101 sulfur amino acid transport(GO:0000101)
0.1 1.5 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.1 0.3 GO:0045976 negative regulation of mitotic cell cycle, embryonic(GO:0045976)
0.1 0.5 GO:0043129 surfactant homeostasis(GO:0043129)
0.1 0.6 GO:0089700 protein kinase D signaling(GO:0089700)
0.1 0.3 GO:2001037 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.1 0.3 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.1 0.3 GO:0061091 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.1 0.6 GO:0018317 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1 0.2 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.1 0.2 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.1 0.2 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.1 0.2 GO:1902725 trans-synaptic signaling by trans-synaptic complex(GO:0099545) negative regulation of satellite cell differentiation(GO:1902725)
0.1 0.3 GO:0034436 glycoprotein transport(GO:0034436)
0.1 0.3 GO:1902617 response to fluoride(GO:1902617)
0.1 0.3 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 0.2 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.1 0.2 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.1 0.1 GO:0021589 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.1 0.4 GO:0097501 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.1 0.5 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.1 0.2 GO:0060178 regulation of exocyst assembly(GO:0001928) regulation of exocyst localization(GO:0060178)
0.1 0.2 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 0.2 GO:0006172 ADP biosynthetic process(GO:0006172) purine deoxyribonucleoside diphosphate biosynthetic process(GO:0009183)
0.1 0.2 GO:1904760 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.1 0.3 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.1 0.2 GO:1900737 regulation of proteinase activated receptor activity(GO:1900276) negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900737)
0.1 0.5 GO:1904684 negative regulation of metalloendopeptidase activity(GO:1904684)
0.1 0.6 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 0.2 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.1 0.2 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.4 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.5 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.1 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.0 0.1 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 0.6 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.2 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0 0.2 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.1 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.5 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.3 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.2 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.0 0.5 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.4 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.2 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.0 0.1 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.0 0.1 GO:0051586 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.0 0.1 GO:0009153 purine deoxyribonucleotide biosynthetic process(GO:0009153)
0.0 0.2 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.2 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.0 0.1 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.4 GO:1902373 negative regulation of mRNA catabolic process(GO:1902373)
0.0 0.2 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.0 0.1 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0 0.1 GO:0060489 dichotomous subdivision of terminal units involved in lung branching(GO:0060448) orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.0 0.1 GO:0006499 N-terminal protein myristoylation(GO:0006499) N-terminal peptidyl-glycine N-myristoylation(GO:0018008)
0.0 0.7 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:0061010 gall bladder development(GO:0061010)
0.0 0.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.1 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.0 0.2 GO:0042126 nitrate metabolic process(GO:0042126)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.2 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.2 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.3 GO:0031054 pre-miRNA processing(GO:0031054)
0.0 0.2 GO:0051013 microtubule severing(GO:0051013)
0.0 0.1 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.7 GO:0006677 glycosylceramide metabolic process(GO:0006677)
0.0 0.1 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.3 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.2 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.0 0.2 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.5 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.2 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.3 GO:0046051 UTP metabolic process(GO:0046051)
0.0 0.0 GO:0060067 cervix development(GO:0060067)
0.0 0.2 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.2 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.4 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.1 GO:0043397 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) regulation of G-protein coupled receptor internalization(GO:1904020)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:0006550 isoleucine catabolic process(GO:0006550)
0.0 0.1 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.2 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.1 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.5 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.0 0.4 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.1 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.1 GO:0033121 regulation of cyclic nucleotide catabolic process(GO:0030805) regulation of cAMP catabolic process(GO:0030820) regulation of purine nucleotide catabolic process(GO:0033121) regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.7 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 0.1 GO:2000567 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.0 0.1 GO:1904978 regulation of endosome organization(GO:1904978) regulation of glucosylceramidase activity(GO:1905123)
0.0 0.1 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0 0.3 GO:0033599 regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.0 0.2 GO:1903012 positive regulation of bone development(GO:1903012)
0.0 0.5 GO:0040036 regulation of fibroblast growth factor receptor signaling pathway(GO:0040036)
0.0 0.1 GO:1904550 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.3 GO:0043586 tongue development(GO:0043586)
0.0 0.2 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177) guanosine-containing compound biosynthetic process(GO:1901070)
0.0 0.2 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.6 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 0.0 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.0 0.4 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.1 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.0 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.0 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.0 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.1 GO:0001886 endothelial cell morphogenesis(GO:0001886) regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.0 0.0 GO:0048627 myoblast development(GO:0048627)
0.0 0.0 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.2 GO:0072112 renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112)
0.0 0.3 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.4 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.0 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.1 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.1 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.2 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.3 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.0 0.4 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.1 GO:0032836 glomerular basement membrane development(GO:0032836)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0031251 PAN complex(GO:0031251)
0.2 0.8 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.7 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 0.5 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 0.4 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.1 0.3 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.1 0.6 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.3 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 1.3 GO:0031045 dense core granule(GO:0031045)
0.1 1.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.2 GO:0043291 RAVE complex(GO:0043291)
0.1 0.4 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 0.2 GO:0039714 viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517)
0.0 0.1 GO:0034657 GID complex(GO:0034657)
0.0 0.3 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.3 GO:0016589 NURF complex(GO:0016589)
0.0 0.5 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.4 GO:0016600 flotillin complex(GO:0016600)
0.0 0.6 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.7 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.3 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.3 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.2 0.6 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.2 0.8 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.2 0.6 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.2 0.5 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.1 0.7 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 0.8 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.8 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.3 GO:0003947 (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity(GO:0003947)
0.1 0.6 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 0.3 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.1 0.5 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.8 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.8 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.2 GO:0035034 histone acetyltransferase regulator activity(GO:0035034)
0.1 0.1 GO:0047322 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
0.1 0.5 GO:0047522 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.1 0.3 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.5 GO:0097108 hedgehog family protein binding(GO:0097108)
0.1 1.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.2 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.1 0.2 GO:1904288 BAT3 complex binding(GO:1904288)
0.1 0.3 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1 0.8 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 0.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.2 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.1 0.2 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 1.1 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.2 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.1 GO:0080130 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.2 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.2 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.0 0.1 GO:0090541 MIT domain binding(GO:0090541)
0.0 0.2 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 0.2 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.2 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.7 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.2 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.1 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.0 0.2 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.6 GO:0031690 adrenergic receptor binding(GO:0031690)
0.0 0.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.2 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.1 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.2 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.4 GO:0030552 cAMP binding(GO:0030552)
0.0 0.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.3 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.7 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 1.4 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.1 GO:0005046 KDEL sequence binding(GO:0005046)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.6 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.3 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.2 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.6 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.0 GO:0003955 NAD(P)H dehydrogenase (quinone) activity(GO:0003955) 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.4 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.1 GO:0023025 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.2 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.0 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.0 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 1.0 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.0 GO:0051500 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.0 0.1 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0 0.5 GO:0005548 phospholipid transporter activity(GO:0005548)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.7 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.6 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 1.0 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.8 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.6 PID IGF1 PATHWAY IGF1 pathway
0.0 0.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.9 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 1.3 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.9 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.7 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.9 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.4 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.3 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 2.0 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.8 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.7 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.0 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.0 0.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.8 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 1.0 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.2 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0 0.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.4 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins