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Inflammatory response time course, HUVEC (Wada et al., 2009)
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Results for UUGGCAC
Z-value: 0.36
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miRNA associated with seed UUGGCAC
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr8_-_22550815 Show fit | 0.72 |
ENST00000317216.2
|
early growth response 3 |
|
| chr4_-_16900217 Show fit | 0.70 |
ENST00000441778.2
|
LIM domain binding 2 |
|
| chr10_-_131762105 Show fit | 0.66 |
ENST00000368648.3
ENST00000355311.5 |
early B-cell factor 3 |
|
| chr9_+_79074068 Show fit | 0.65 |
ENST00000444201.2
ENST00000376730.4 |
glucosaminyl (N-acetyl) transferase 1, core 2 |
|
| chr3_+_193853927 Show fit | 0.50 |
ENST00000232424.3
|
hes family bHLH transcription factor 1 |
|
| chr2_+_173600671 Show fit | 0.47 |
ENST00000409036.1
|
Rap guanine nucleotide exchange factor (GEF) 4 |
|
| chr3_+_39851094 Show fit | 0.46 |
ENST00000302541.6
|
myosin VIIA and Rab interacting protein |
|
| chr8_+_37654424 Show fit | 0.43 |
ENST00000315215.7
|
G protein-coupled receptor 124 |
|
| chr1_-_209979375 Show fit | 0.39 |
ENST00000367021.3
|
interferon regulatory factor 6 |
|
| chr13_+_58206655 Show fit | 0.37 |
ENST00000377918.3
|
protocadherin 17 |
Network of associatons between targets according to the STRING database.
First level regulatory network of UUGGCAC
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.8 | GO:0060352 | cell adhesion molecule production(GO:0060352) |
| 0.1 | 0.7 | GO:0045586 | regulation of gamma-delta T cell differentiation(GO:0045586) |
| 0.0 | 0.7 | GO:0010669 | epithelial structure maintenance(GO:0010669) |
| 0.2 | 0.5 | GO:0060164 | trochlear nerve development(GO:0021558) auditory receptor cell fate determination(GO:0042668) negative regulation of auditory receptor cell differentiation(GO:0045608) regulation of timing of neuron differentiation(GO:0060164) negative regulation of pro-B cell differentiation(GO:2000974) |
| 0.0 | 0.5 | GO:0030050 | vesicle transport along actin filament(GO:0030050) |
| 0.1 | 0.4 | GO:0090118 | receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118) |
| 0.0 | 0.4 | GO:2000807 | regulation of synaptic vesicle clustering(GO:2000807) |
| 0.0 | 0.4 | GO:0043586 | tongue development(GO:0043586) |
| 0.1 | 0.3 | GO:1905205 | positive regulation of connective tissue replacement(GO:1905205) |
| 0.1 | 0.3 | GO:0072720 | response to dithiothreitol(GO:0072720) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.5 | GO:0031045 | dense core granule(GO:0031045) |
| 0.1 | 0.3 | GO:0034751 | aryl hydrocarbon receptor complex(GO:0034751) |
| 0.0 | 0.3 | GO:0042272 | nuclear RNA export factor complex(GO:0042272) |
| 0.1 | 0.2 | GO:1990851 | Wnt-Frizzled-LRP5/6 complex(GO:1990851) |
| 0.1 | 0.2 | GO:1990622 | CHOP-ATF3 complex(GO:1990622) |
| 0.0 | 0.2 | GO:0031251 | PAN complex(GO:0031251) |
| 0.0 | 0.2 | GO:0032144 | 4-aminobutyrate transaminase complex(GO:0032144) |
| 0.0 | 0.2 | GO:0071148 | TEAD-1-YAP complex(GO:0071148) |
| 0.0 | 0.2 | GO:0030121 | AP-1 adaptor complex(GO:0030121) |
| 0.0 | 0.2 | GO:0061700 | GATOR2 complex(GO:0061700) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 0.8 | GO:0003829 | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829) |
| 0.1 | 0.8 | GO:0030274 | LIM domain binding(GO:0030274) |
| 0.1 | 0.3 | GO:0004874 | aryl hydrocarbon receptor activity(GO:0004874) |
| 0.0 | 0.3 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
| 0.0 | 0.3 | GO:0043237 | laminin-1 binding(GO:0043237) |
| 0.0 | 0.3 | GO:0033192 | calmodulin-dependent protein phosphatase activity(GO:0033192) |
| 0.0 | 0.3 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.0 | 0.3 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.0 | 0.3 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.0 | 0.3 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | ST PAC1 RECEPTOR PATHWAY | PAC1 Receptor Pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.2 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.0 | 0.5 | REACTOME REGULATION OF BETA CELL DEVELOPMENT | Genes involved in Regulation of beta-cell development |
| 0.0 | 0.5 | REACTOME RAP1 SIGNALLING | Genes involved in Rap1 signalling |
| 0.0 | 0.2 | REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |