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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for VAX1_GSX2

Z-value: 0.48

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Transcription factors associated with VAX1_GSX2

Gene Symbol Gene ID Gene Info
VAX1
ENSG00000148704.8 ventral anterior homeobox 1
GSX2
ENSG00000180613.6 GS homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GSX2hg19_v2_chr4_+_54966198_549663400.262.0e-01Click!

Activity profile of VAX1_GSX2 motif

Sorted Z-values of VAX1_GSX2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_92777606 1.79 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L
sterile alpha motif domain containing 9-like
chr11_-_102651343 1.30 ENST00000279441.4
ENST00000539681.1
MMP10
matrix metallopeptidase 10 (stromelysin 2)
chr21_-_35899113 1.10 ENST00000492600.1
ENST00000481448.1
ENST00000381132.2
RCAN1
regulator of calcineurin 1
chr9_-_16728161 0.88 ENST00000603713.1
ENST00000603313.1
BNC2
basonuclin 2
chr3_+_111717511 0.85 ENST00000478951.1
ENST00000393917.2
TAGLN3
transgelin 3
chr3_+_111717600 0.84 ENST00000273368.4
TAGLN3
transgelin 3
chr3_+_111718036 0.76 ENST00000455401.2
TAGLN3
transgelin 3
chr4_-_119759795 0.74 ENST00000419654.2
SEC24D
SEC24 family member D
chr15_-_75748115 0.68 ENST00000360439.4
SIN3A
SIN3 transcription regulator family member A
chr5_-_150473127 0.66 ENST00000521001.1
TNIP1
TNFAIP3 interacting protein 1
chr7_+_100770328 0.63 ENST00000223095.4
ENST00000445463.2
SERPINE1
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr22_-_32651326 0.53 ENST00000266086.4
SLC5A4
solute carrier family 5 (glucose activated ion channel), member 4
chr6_+_127898312 0.51 ENST00000329722.7
C6orf58
chromosome 6 open reading frame 58
chr15_-_55562479 0.48 ENST00000564609.1
RAB27A
RAB27A, member RAS oncogene family
chr15_-_55562582 0.46 ENST00000396307.2
RAB27A
RAB27A, member RAS oncogene family
chr15_-_55563072 0.44 ENST00000567380.1
ENST00000565972.1
ENST00000569493.1
RAB27A
RAB27A, member RAS oncogene family
chr7_-_81399411 0.44 ENST00000423064.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr13_+_32313658 0.44 ENST00000380314.1
ENST00000298386.2
RXFP2
relaxin/insulin-like family peptide receptor 2
chr1_+_192778161 0.43 ENST00000235382.5
RGS2
regulator of G-protein signaling 2, 24kDa
chr5_+_66300446 0.41 ENST00000261569.7
MAST4
microtubule associated serine/threonine kinase family member 4
chr1_+_101003687 0.40 ENST00000315033.4
GPR88
G protein-coupled receptor 88
chr2_-_208031943 0.37 ENST00000421199.1
ENST00000457962.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr2_-_220264703 0.36 ENST00000519905.1
ENST00000523282.1
ENST00000434339.1
ENST00000457935.1
DNPEP
aspartyl aminopeptidase
chr1_-_185597619 0.36 ENST00000608417.1
ENST00000436955.1
GS1-204I12.1
GS1-204I12.1
chr3_+_50273625 0.35 ENST00000536647.1
GNAI2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr2_+_102953608 0.35 ENST00000311734.2
ENST00000409584.1
IL1RL1
interleukin 1 receptor-like 1
chr1_-_205325850 0.33 ENST00000537168.1
KLHDC8A
kelch domain containing 8A
chr22_+_24990746 0.33 ENST00000456869.1
ENST00000411974.1
GGT1
gamma-glutamyltransferase 1
chr8_-_10512569 0.31 ENST00000382483.3
RP1L1
retinitis pigmentosa 1-like 1
chr7_-_99717463 0.31 ENST00000437822.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr20_-_50418972 0.30 ENST00000395997.3
SALL4
spalt-like transcription factor 4
chr4_-_39979576 0.30 ENST00000303538.8
ENST00000503396.1
PDS5A
PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr3_-_112565703 0.30 ENST00000488794.1
CD200R1L
CD200 receptor 1-like
chr21_-_43346790 0.29 ENST00000329623.7
C2CD2
C2 calcium-dependent domain containing 2
chr20_-_50418947 0.29 ENST00000371539.3
SALL4
spalt-like transcription factor 4
chr6_+_26440700 0.28 ENST00000494393.1
ENST00000482451.1
ENST00000244519.2
ENST00000339789.4
ENST00000471353.1
ENST00000361232.3
ENST00000487627.1
ENST00000496719.1
ENST00000490254.1
ENST00000487272.1
BTN3A3
butyrophilin, subfamily 3, member A3
chr8_+_54764346 0.28 ENST00000297313.3
ENST00000344277.6
RGS20
regulator of G-protein signaling 20
chr19_+_48949030 0.28 ENST00000253237.5
GRWD1
glutamate-rich WD repeat containing 1
chr17_+_43238438 0.28 ENST00000593138.1
ENST00000586681.1
HEXIM2
hexamethylene bis-acetamide inducible 2
chr6_+_26402465 0.27 ENST00000476549.2
ENST00000289361.6
ENST00000450085.2
ENST00000425234.2
ENST00000427334.1
ENST00000506698.1
BTN3A1
butyrophilin, subfamily 3, member A1
chr6_+_26365443 0.26 ENST00000527422.1
ENST00000356386.2
ENST00000396934.3
ENST00000377708.2
ENST00000396948.1
ENST00000508906.2
BTN3A2
butyrophilin, subfamily 3, member A2
chr4_+_144354644 0.26 ENST00000512843.1
GAB1
GRB2-associated binding protein 1
chr22_-_39636914 0.26 ENST00000381551.4
PDGFB
platelet-derived growth factor beta polypeptide
chr22_-_39637135 0.25 ENST00000440375.1
PDGFB
platelet-derived growth factor beta polypeptide
chr4_+_70894130 0.25 ENST00000526767.1
ENST00000530128.1
ENST00000381057.3
HTN3
histatin 3
chr1_-_150669500 0.25 ENST00000271732.3
GOLPH3L
golgi phosphoprotein 3-like
chr2_-_136678123 0.25 ENST00000422708.1
DARS
aspartyl-tRNA synthetase
chr11_-_26593677 0.25 ENST00000527569.1
MUC15
mucin 15, cell surface associated
chr15_+_64680003 0.25 ENST00000261884.3
TRIP4
thyroid hormone receptor interactor 4
chr4_+_110736659 0.24 ENST00000394631.3
ENST00000226796.6
GAR1
GAR1 ribonucleoprotein
chr20_+_816695 0.24 ENST00000246100.3
FAM110A
family with sequence similarity 110, member A
chr11_-_26593779 0.23 ENST00000529533.1
MUC15
mucin 15, cell surface associated
chr11_+_65554493 0.23 ENST00000335987.3
OVOL1
ovo-like zinc finger 1
chr12_+_18414446 0.23 ENST00000433979.1
PIK3C2G
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
chr1_+_53925063 0.23 ENST00000371445.3
DMRTB1
DMRT-like family B with proline-rich C-terminal, 1
chrX_-_21676442 0.23 ENST00000379499.2
KLHL34
kelch-like family member 34
chr17_+_39261584 0.23 ENST00000391415.1
KRTAP4-9
keratin associated protein 4-9
chr6_+_29079668 0.22 ENST00000377169.1
OR2J3
olfactory receptor, family 2, subfamily J, member 3
chr17_+_12569306 0.21 ENST00000425538.1
MYOCD
myocardin
chr20_+_31805131 0.21 ENST00000375454.3
ENST00000375452.3
BPIFA3
BPI fold containing family A, member 3
chr15_+_75491213 0.21 ENST00000360639.2
C15orf39
chromosome 15 open reading frame 39
chr11_+_33061543 0.21 ENST00000432887.1
ENST00000528898.1
ENST00000531632.2
TCP11L1
t-complex 11, testis-specific-like 1
chr17_-_39324424 0.21 ENST00000391356.2
KRTAP4-3
keratin associated protein 4-3
chr3_-_99569821 0.21 ENST00000487087.1
FILIP1L
filamin A interacting protein 1-like
chr4_+_86525299 0.20 ENST00000512201.1
ARHGAP24
Rho GTPase activating protein 24
chr3_+_149191723 0.20 ENST00000305354.4
TM4SF4
transmembrane 4 L six family member 4
chr3_-_191000172 0.19 ENST00000427544.2
UTS2B
urotensin 2B
chr17_+_59489112 0.19 ENST00000335108.2
C17orf82
chromosome 17 open reading frame 82
chr11_-_71823266 0.19 ENST00000538919.1
ENST00000539395.1
ENST00000542531.1
ANAPC15
anaphase promoting complex subunit 15
chr11_-_71823796 0.19 ENST00000545680.1
ENST00000543587.1
ENST00000538393.1
ENST00000535234.1
ENST00000227618.4
ENST00000535503.1
ANAPC15
anaphase promoting complex subunit 15
chr1_+_160160346 0.18 ENST00000368078.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr4_-_8873531 0.18 ENST00000400677.3
HMX1
H6 family homeobox 1
chr15_-_42264702 0.18 ENST00000220325.4
EHD4
EH-domain containing 4
chr3_+_121774202 0.18 ENST00000469710.1
ENST00000493101.1
ENST00000330540.2
ENST00000264468.5
CD86
CD86 molecule
chr1_+_160160283 0.18 ENST00000368079.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr10_+_96443378 0.18 ENST00000285979.6
CYP2C18
cytochrome P450, family 2, subfamily C, polypeptide 18
chr11_-_36619771 0.18 ENST00000311485.3
ENST00000527033.1
ENST00000532616.1
RAG2
recombination activating gene 2
chr14_+_95027772 0.17 ENST00000555095.1
ENST00000298841.5
ENST00000554220.1
ENST00000553780.1
SERPINA4
SERPINA5
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr15_-_64665911 0.17 ENST00000606793.1
ENST00000561349.1
ENST00000560278.1
CTD-2116N17.1
Uncharacterized protein
chr9_+_111624577 0.17 ENST00000333999.3
ACTL7A
actin-like 7A
chr6_-_87804815 0.17 ENST00000369582.2
CGA
glycoprotein hormones, alpha polypeptide
chr11_+_60163775 0.17 ENST00000300187.6
ENST00000395005.2
MS4A14
membrane-spanning 4-domains, subfamily A, member 14
chr11_-_71823715 0.17 ENST00000545944.1
ENST00000502597.2
ANAPC15
anaphase promoting complex subunit 15
chr19_-_58951496 0.17 ENST00000254166.3
ZNF132
zinc finger protein 132
chr12_+_56862301 0.16 ENST00000338146.5
SPRYD4
SPRY domain containing 4
chr1_-_1709845 0.16 ENST00000341426.5
ENST00000344463.4
NADK
NAD kinase
chr2_-_40680578 0.16 ENST00000455476.1
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr20_+_43990576 0.16 ENST00000372727.1
ENST00000414310.1
SYS1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr3_+_111393501 0.16 ENST00000393934.3
PLCXD2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr3_+_111718173 0.16 ENST00000494932.1
TAGLN3
transgelin 3
chr6_+_46761118 0.16 ENST00000230588.4
MEP1A
meprin A, alpha (PABA peptide hydrolase)
chr17_-_73901494 0.15 ENST00000309352.3
MRPL38
mitochondrial ribosomal protein L38
chr6_+_160542821 0.15 ENST00000366963.4
SLC22A1
solute carrier family 22 (organic cation transporter), member 1
chr9_+_125132803 0.15 ENST00000540753.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr1_+_160370344 0.15 ENST00000368061.2
VANGL2
VANGL planar cell polarity protein 2
chr20_-_50419055 0.15 ENST00000217086.4
SALL4
spalt-like transcription factor 4
chr6_+_31895254 0.14 ENST00000299367.5
ENST00000442278.2
C2
complement component 2
chr4_-_103749205 0.14 ENST00000508249.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr12_+_26348246 0.14 ENST00000422622.2
SSPN
sarcospan
chr14_+_100485712 0.14 ENST00000544450.2
EVL
Enah/Vasp-like
chr2_+_228736335 0.14 ENST00000440997.1
ENST00000545118.1
DAW1
dynein assembly factor with WDR repeat domains 1
chr12_-_57039739 0.14 ENST00000552959.1
ENST00000551020.1
ENST00000553007.2
ENST00000552919.1
ENST00000552104.1
ENST00000262030.3
ATP5B
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
chr14_-_57272366 0.14 ENST00000554788.1
ENST00000554845.1
ENST00000408990.3
OTX2
orthodenticle homeobox 2
chr12_+_7014126 0.14 ENST00000415834.1
ENST00000436789.1
LRRC23
leucine rich repeat containing 23
chr4_+_70796784 0.14 ENST00000246891.4
ENST00000444405.3
CSN1S1
casein alpha s1
chr1_-_67266939 0.14 ENST00000304526.2
INSL5
insulin-like 5
chr17_-_3030875 0.14 ENST00000328890.2
OR1G1
olfactory receptor, family 1, subfamily G, member 1
chr15_+_62853562 0.13 ENST00000561311.1
TLN2
talin 2
chr17_-_2996290 0.13 ENST00000331459.1
OR1D2
olfactory receptor, family 1, subfamily D, member 2
chr6_+_26402517 0.13 ENST00000414912.2
BTN3A1
butyrophilin, subfamily 3, member A1
chr1_-_1710229 0.13 ENST00000341991.3
NADK
NAD kinase
chr11_-_121986923 0.13 ENST00000560104.1
BLID
BH3-like motif containing, cell death inducer
chr10_+_24755416 0.12 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
KIAA1217
chr7_-_99716952 0.12 ENST00000523306.1
ENST00000344095.4
ENST00000417349.1
ENST00000493322.1
ENST00000520135.1
ENST00000418432.2
ENST00000460673.2
ENST00000452041.1
ENST00000452438.2
ENST00000451699.1
ENST00000453269.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr16_+_14280742 0.12 ENST00000341243.5
MKL2
MKL/myocardin-like 2
chr7_+_156433573 0.12 ENST00000311822.8
RNF32
ring finger protein 32
chr7_-_81399438 0.11 ENST00000222390.5
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr15_+_89631647 0.11 ENST00000569550.1
ENST00000565066.1
ENST00000565973.1
ABHD2
abhydrolase domain containing 2
chr5_+_140557371 0.11 ENST00000239444.2
PCDHB8
protocadherin beta 8
chr11_+_5710919 0.11 ENST00000379965.3
ENST00000425490.1
TRIM22
tripartite motif containing 22
chrX_+_144908928 0.11 ENST00000408967.2
TMEM257
transmembrane protein 257
chr1_-_152386732 0.11 ENST00000271835.3
CRNN
cornulin
chr7_+_55433131 0.11 ENST00000254770.2
LANCL2
LanC lantibiotic synthetase component C-like 2 (bacterial)
chr7_-_33102338 0.11 ENST00000610140.1
NT5C3A
5'-nucleotidase, cytosolic IIIA
chr7_+_120628731 0.11 ENST00000310396.5
CPED1
cadherin-like and PC-esterase domain containing 1
chr1_-_109618566 0.11 ENST00000338366.5
TAF13
TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
chr1_-_150669604 0.11 ENST00000427665.1
ENST00000540514.1
GOLPH3L
golgi phosphoprotein 3-like
chr19_-_19887185 0.11 ENST00000590092.1
ENST00000589910.1
ENST00000589508.1
ENST00000586645.1
ENST00000586816.1
ENST00000588223.1
ENST00000586885.1
LINC00663
long intergenic non-protein coding RNA 663
chr7_-_33102399 0.10 ENST00000242210.7
NT5C3A
5'-nucleotidase, cytosolic IIIA
chr8_+_92261516 0.10 ENST00000276609.3
ENST00000309536.2
SLC26A7
solute carrier family 26 (anion exchanger), member 7
chr16_+_31885079 0.10 ENST00000300870.10
ENST00000394846.3
ZNF267
zinc finger protein 267
chr1_-_92952433 0.10 ENST00000294702.5
GFI1
growth factor independent 1 transcription repressor
chr6_+_160542870 0.10 ENST00000324965.4
ENST00000457470.2
SLC22A1
solute carrier family 22 (organic cation transporter), member 1
chr17_-_72772462 0.10 ENST00000582870.1
ENST00000581136.1
ENST00000357814.3
ENST00000579218.1
ENST00000583476.1
ENST00000580301.1
ENST00000583757.1
ENST00000582524.1
NAT9
N-acetyltransferase 9 (GCN5-related, putative)
chr2_-_128284020 0.09 ENST00000295321.4
ENST00000455721.2
IWS1
IWS1 homolog (S. cerevisiae)
chr15_+_90118723 0.09 ENST00000560985.1
TICRR
TOPBP1-interacting checkpoint and replication regulator
chr4_-_159956333 0.09 ENST00000434826.2
C4orf45
chromosome 4 open reading frame 45
chr19_-_19302931 0.09 ENST00000444486.3
ENST00000514819.3
ENST00000585679.1
ENST00000162023.5
MEF2BNB-MEF2B
MEF2BNB
MEF2B
MEF2BNB-MEF2B readthrough
MEF2B neighbor
myocyte enhancer factor 2B
chr5_-_98262240 0.09 ENST00000284049.3
CHD1
chromodomain helicase DNA binding protein 1
chr2_-_169887827 0.09 ENST00000263817.6
ABCB11
ATP-binding cassette, sub-family B (MDR/TAP), member 11
chr3_+_138340049 0.09 ENST00000464668.1
FAIM
Fas apoptotic inhibitory molecule
chr6_+_29274403 0.08 ENST00000377160.2
OR14J1
olfactory receptor, family 14, subfamily J, member 1
chr13_+_73632897 0.08 ENST00000377687.4
KLF5
Kruppel-like factor 5 (intestinal)
chr1_+_28199047 0.08 ENST00000373925.1
ENST00000328928.7
ENST00000373927.3
ENST00000427466.1
ENST00000442118.1
ENST00000373921.3
THEMIS2
thymocyte selection associated family member 2
chr2_-_166930131 0.08 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
SCN1A
sodium channel, voltage-gated, type I, alpha subunit
chr12_-_22063787 0.08 ENST00000544039.1
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr15_+_90118685 0.08 ENST00000268138.7
TICRR
TOPBP1-interacting checkpoint and replication regulator
chr18_+_22040620 0.08 ENST00000426880.2
HRH4
histamine receptor H4
chrX_-_109590174 0.08 ENST00000372054.1
GNG5P2
guanine nucleotide binding protein (G protein), gamma 5 pseudogene 2
chr1_+_117544366 0.08 ENST00000256652.4
ENST00000369470.1
CD101
CD101 molecule
chr1_-_207226313 0.08 ENST00000367084.1
YOD1
YOD1 deubiquitinase
chr3_+_130569429 0.07 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr19_+_50180317 0.07 ENST00000534465.1
PRMT1
protein arginine methyltransferase 1
chr7_-_81399329 0.07 ENST00000453411.1
ENST00000444829.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr12_+_49121213 0.07 ENST00000548380.1
LINC00935
long intergenic non-protein coding RNA 935
chr1_+_12834984 0.07 ENST00000357726.4
PRAMEF12
PRAME family member 12
chr2_+_90198535 0.07 ENST00000390276.2
IGKV1D-12
immunoglobulin kappa variable 1D-12
chr7_-_100860851 0.07 ENST00000223127.3
PLOD3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr2_-_203735586 0.07 ENST00000454326.1
ENST00000432273.1
ENST00000450143.1
ENST00000411681.1
ICA1L
islet cell autoantigen 1,69kDa-like
chr2_-_99871570 0.07 ENST00000333017.2
ENST00000409679.1
ENST00000423306.1
LYG2
lysozyme G-like 2
chr4_+_119809984 0.07 ENST00000307142.4
ENST00000448416.2
ENST00000429713.2
SYNPO2
synaptopodin 2
chr1_+_42928945 0.07 ENST00000428554.2
CCDC30
coiled-coil domain containing 30
chr4_-_103749105 0.06 ENST00000394801.4
ENST00000394804.2
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr11_+_118398178 0.06 ENST00000302783.4
ENST00000539546.1
TTC36
tetratricopeptide repeat domain 36
chr3_+_138340067 0.06 ENST00000479848.1
FAIM
Fas apoptotic inhibitory molecule
chr4_+_78432907 0.06 ENST00000286758.4
CXCL13
chemokine (C-X-C motif) ligand 13
chr16_-_31085514 0.06 ENST00000300849.4
ZNF668
zinc finger protein 668
chr11_+_24518723 0.06 ENST00000336930.6
ENST00000529015.1
ENST00000533227.1
LUZP2
leucine zipper protein 2
chr7_-_87342564 0.06 ENST00000265724.3
ENST00000416177.1
ABCB1
ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr16_-_1464688 0.06 ENST00000389221.4
ENST00000508903.2
ENST00000397462.1
ENST00000301712.5
UNKL
unkempt family zinc finger-like
chr2_+_210517895 0.06 ENST00000447185.1
MAP2
microtubule-associated protein 2
chrX_-_13835147 0.06 ENST00000493677.1
ENST00000355135.2
GPM6B
glycoprotein M6B
chr3_-_141747950 0.06 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr1_+_28261492 0.06 ENST00000373894.3
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr10_-_61900762 0.06 ENST00000355288.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr3_+_157154578 0.05 ENST00000295927.3
PTX3
pentraxin 3, long
chr10_+_91461337 0.05 ENST00000260753.4
ENST00000416354.1
ENST00000394289.2
ENST00000371728.3
KIF20B
kinesin family member 20B
chrX_-_70326455 0.05 ENST00000374251.5
CXorf65
chromosome X open reading frame 65
chr9_-_132383055 0.05 ENST00000372478.4
C9orf50
chromosome 9 open reading frame 50
chr7_+_93535866 0.05 ENST00000429473.1
ENST00000430875.1
ENST00000428834.1
GNGT1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr12_+_26348429 0.05 ENST00000242729.2
SSPN
sarcospan
chr14_+_32798462 0.05 ENST00000280979.4
AKAP6
A kinase (PRKA) anchor protein 6
chr3_-_101039402 0.05 ENST00000193391.7
IMPG2
interphotoreceptor matrix proteoglycan 2
chr11_-_13517565 0.05 ENST00000282091.1
ENST00000529816.1
PTH
parathyroid hormone
chr2_-_89340242 0.05 ENST00000480492.1
IGKV1-12
immunoglobulin kappa variable 1-12
chr11_+_27015628 0.05 ENST00000318627.2
FIBIN
fin bud initiation factor homolog (zebrafish)
chr5_-_139726181 0.05 ENST00000507104.1
ENST00000230990.6
HBEGF
heparin-binding EGF-like growth factor
chr18_+_22040593 0.05 ENST00000256906.4
HRH4
histamine receptor H4
chr11_+_59824060 0.05 ENST00000395032.2
ENST00000358152.2
MS4A3
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr16_-_66764119 0.05 ENST00000569320.1
DYNC1LI2
dynein, cytoplasmic 1, light intermediate chain 2
chr13_-_41593425 0.05 ENST00000239882.3
ELF1
E74-like factor 1 (ets domain transcription factor)
chr2_-_50201327 0.05 ENST00000412315.1
NRXN1
neurexin 1
chr3_+_186353756 0.04 ENST00000431018.1
ENST00000450521.1
ENST00000539949.1
FETUB
fetuin B
chrX_-_77225135 0.04 ENST00000458128.1
PGAM4
phosphoglycerate mutase family member 4
chr1_+_40713573 0.04 ENST00000372766.3
TMCO2
transmembrane and coiled-coil domains 2
chr11_+_59824127 0.04 ENST00000278865.3
MS4A3
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr2_-_134326009 0.04 ENST00000409261.1
ENST00000409213.1
NCKAP5
NCK-associated protein 5
chr18_-_67624160 0.04 ENST00000581982.1
ENST00000280200.4
CD226
CD226 molecule
chr4_-_103749179 0.04 ENST00000502690.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr11_-_128894053 0.04 ENST00000392657.3
ARHGAP32
Rho GTPase activating protein 32

Network of associatons between targets according to the STRING database.

First level regulatory network of VAX1_GSX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.2 0.6 GO:2000097 chronological cell aging(GO:0001300) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.2 0.7 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.2 0.7 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.2 1.8 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.5 GO:1900241 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.1 0.4 GO:0061743 motor learning(GO:0061743)
0.1 0.2 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 0.2 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.1 0.2 GO:1901993 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.1 0.2 GO:1900222 regulation of cell growth by extracellular stimulus(GO:0001560) phenotypic switching(GO:0036166) negative regulation of beta-amyloid clearance(GO:1900222) regulation of phenotypic switching(GO:1900239)
0.1 0.6 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 0.2 GO:0045404 negative regulation of tolerance induction(GO:0002644) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.1 0.3 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.1 0.4 GO:0071877 regulation of adrenergic receptor signaling pathway(GO:0071877)
0.0 0.1 GO:0061341 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.0 0.7 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.2 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.3 GO:0048241 epinephrine transport(GO:0048241)
0.0 0.3 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.7 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.2 GO:0061107 seminal vesicle development(GO:0061107)
0.0 0.4 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.3 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.0 0.1 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.4 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.9 GO:0043586 tongue development(GO:0043586)
0.0 1.1 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.7 GO:0072643 interferon-gamma secretion(GO:0072643)
0.0 0.1 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.1 GO:0046985 negative regulation of megakaryocyte differentiation(GO:0045653) positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0 0.4 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.2 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.2 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.1 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 0.1 GO:1990167 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.0 0.1 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.1 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.0 0.1 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.0 0.1 GO:1901419 regulation of response to alcohol(GO:1901419)
0.0 0.3 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.0 0.5 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.1 GO:2001027 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0 1.3 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.0 GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.0 0.1 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.4 GO:0001556 oocyte maturation(GO:0001556)
0.0 0.1 GO:0032954 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.0 0.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.1 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.0 GO:0051541 elastin metabolic process(GO:0051541)
0.0 0.0 GO:0061114 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.0 0.0 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.1 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.1 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.2 GO:0036030 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.0 0.4 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.2 GO:0090661 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.7 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.4 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.7 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 1.8 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.2 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.2 GO:0001673 male germ cell nucleus(GO:0001673)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.3 GO:0002113 interleukin-33 binding(GO:0002113)
0.1 0.3 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.1 0.5 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.2 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 1.4 GO:0031489 myosin V binding(GO:0031489)
0.0 0.2 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.5 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.4 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.1 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.1 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.0 0.3 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.2 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.4 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.3 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.1 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.2 GO:0032190 acrosin binding(GO:0032190)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.0 0.7 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.7 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.1 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.0 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.5 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 1.2 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 1.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.3 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 1.2 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.1 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.3 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.7 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.3 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.9 REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer