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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for XBP1

Z-value: 1.56

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Transcription factors associated with XBP1

Gene Symbol Gene ID Gene Info
XBP1
ENSG00000100219.12 X-box binding protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
XBP1hg19_v2_chr22_-_29196546_291965850.395.2e-02Click!

Activity profile of XBP1 motif

Sorted Z-values of XBP1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_121413974 4.99 ENST00000231004.4
LOX
lysyl oxidase
chr9_+_35732312 4.22 ENST00000353704.2
CREB3
cAMP responsive element binding protein 3
chr11_+_69455855 3.43 ENST00000227507.2
ENST00000536559.1
CCND1
cyclin D1
chr8_+_104384616 3.21 ENST00000520337.1
CTHRC1
collagen triple helix repeat containing 1
chr6_+_116692102 3.00 ENST00000359564.2
DSE
dermatan sulfate epimerase
chr20_-_62199427 2.87 ENST00000427522.2
HELZ2
helicase with zinc finger 2, transcriptional coactivator
chr1_-_144932464 2.85 ENST00000479408.2
PDE4DIP
phosphodiesterase 4D interacting protein
chr2_-_69614373 2.70 ENST00000361060.5
ENST00000357308.4
GFPT1
glutamine--fructose-6-phosphate transaminase 1
chr3_+_105086056 2.61 ENST00000472644.2
ALCAM
activated leukocyte cell adhesion molecule
chr1_+_101361782 2.60 ENST00000357650.4
SLC30A7
solute carrier family 30 (zinc transporter), member 7
chr21_-_18985158 2.57 ENST00000339775.6
BTG3
BTG family, member 3
chr1_-_11120057 2.40 ENST00000376957.2
SRM
spermidine synthase
chr10_-_105615164 2.40 ENST00000355946.2
ENST00000369774.4
SH3PXD2A
SH3 and PX domains 2A
chr6_+_132891461 2.28 ENST00000275198.1
TAAR6
trace amine associated receptor 6
chr6_-_83902933 2.25 ENST00000512866.1
ENST00000510258.1
ENST00000503094.1
ENST00000283977.4
ENST00000513973.1
ENST00000508748.1
PGM3
phosphoglucomutase 3
chr22_-_31503490 2.21 ENST00000400299.2
SELM
Selenoprotein M
chr11_-_64646086 2.10 ENST00000320631.3
EHD1
EH-domain containing 1
chr21_-_18985230 2.02 ENST00000457956.1
ENST00000348354.6
BTG3
BTG family, member 3
chr6_+_83903061 1.94 ENST00000369724.4
ENST00000539997.1
RWDD2A
RWD domain containing 2A
chr11_-_207221 1.93 ENST00000486280.1
ENST00000332865.6
ENST00000529614.2
ENST00000325147.9
ENST00000410108.1
ENST00000382762.3
BET1L
Bet1 golgi vesicular membrane trafficking protein-like
chr6_-_90062543 1.88 ENST00000435041.2
UBE2J1
ubiquitin-conjugating enzyme E2, J1
chr7_+_100547156 1.87 ENST00000379458.4
MUC3A
Protein LOC100131514
chr1_-_144932316 1.81 ENST00000313431.9
PDE4DIP
phosphodiesterase 4D interacting protein
chr4_-_119757239 1.80 ENST00000280551.6
SEC24D
SEC24 family member D
chr12_+_107349497 1.76 ENST00000548125.1
ENST00000280756.4
C12orf23
chromosome 12 open reading frame 23
chrX_+_9431324 1.67 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X
transducin (beta)-like 1X-linked
chr14_+_50087468 1.65 ENST00000305386.2
MGAT2
mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr1_-_144932014 1.64 ENST00000529945.1
PDE4DIP
phosphodiesterase 4D interacting protein
chr17_+_8339164 1.59 ENST00000582665.1
ENST00000334527.7
ENST00000299734.7
NDEL1
nudE neurodevelopment protein 1-like 1
chr1_+_26758790 1.57 ENST00000427245.2
ENST00000525682.2
ENST00000236342.7
ENST00000526219.1
ENST00000374185.3
ENST00000360009.2
DHDDS
dehydrodolichyl diphosphate synthase
chr6_+_33168637 1.57 ENST00000374677.3
SLC39A7
solute carrier family 39 (zinc transporter), member 7
chr17_+_8339189 1.55 ENST00000585098.1
ENST00000380025.4
ENST00000402554.3
ENST00000584866.1
ENST00000582490.1
NDEL1
nudE neurodevelopment protein 1-like 1
chr5_+_126853301 1.54 ENST00000296666.8
ENST00000442138.2
ENST00000512635.2
PRRC1
proline-rich coiled-coil 1
chr11_+_207477 1.54 ENST00000526104.1
RIC8A
RIC8 guanine nucleotide exchange factor A
chr15_-_43622736 1.54 ENST00000544735.1
ENST00000567039.1
ENST00000305641.5
LCMT2
leucine carboxyl methyltransferase 2
chr21_+_45138941 1.53 ENST00000398081.1
ENST00000468090.1
ENST00000291565.4
PDXK
pyridoxal (pyridoxine, vitamin B6) kinase
chr6_+_33168597 1.52 ENST00000374675.3
SLC39A7
solute carrier family 39 (zinc transporter), member 7
chr1_-_145039949 1.48 ENST00000313382.9
PDE4DIP
phosphodiesterase 4D interacting protein
chr4_-_119757322 1.48 ENST00000379735.5
SEC24D
SEC24 family member D
chr12_-_121712313 1.45 ENST00000392474.2
CAMKK2
calcium/calmodulin-dependent protein kinase kinase 2, beta
chr19_-_10444188 1.44 ENST00000293677.6
RAVER1
ribonucleoprotein, PTB-binding 1
chr3_-_156272924 1.43 ENST00000467789.1
ENST00000265044.2
SSR3
signal sequence receptor, gamma (translocon-associated protein gamma)
chr2_+_171785824 1.41 ENST00000452526.2
GORASP2
golgi reassembly stacking protein 2, 55kDa
chr6_+_138483058 1.41 ENST00000251691.4
KIAA1244
KIAA1244
chr13_+_46039037 1.38 ENST00000349995.5
COG3
component of oligomeric golgi complex 3
chr3_+_127771212 1.37 ENST00000243253.3
ENST00000481210.1
SEC61A1
Sec61 alpha 1 subunit (S. cerevisiae)
chr6_-_43596899 1.37 ENST00000307126.5
ENST00000452781.1
GTPBP2
GTP binding protein 2
chr5_-_9546180 1.36 ENST00000382496.5
SEMA5A
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr20_+_32951070 1.35 ENST00000535650.1
ENST00000262650.6
ITCH
itchy E3 ubiquitin protein ligase
chr3_-_57583185 1.30 ENST00000463880.1
ARF4
ADP-ribosylation factor 4
chr5_+_176730769 1.30 ENST00000303204.4
ENST00000503216.1
PRELID1
PRELI domain containing 1
chr7_-_30066233 1.28 ENST00000222803.5
FKBP14
FK506 binding protein 14, 22 kDa
chr2_-_33824336 1.26 ENST00000431950.1
ENST00000403368.1
ENST00000441530.2
FAM98A
family with sequence similarity 98, member A
chr11_-_62599505 1.25 ENST00000377897.4
ENST00000394690.1
ENST00000541317.1
ENST00000294179.3
STX5
syntaxin 5
chr11_-_59383617 1.20 ENST00000263847.1
OSBP
oxysterol binding protein
chr2_-_33824382 1.20 ENST00000238823.8
FAM98A
family with sequence similarity 98, member A
chr2_+_27255806 1.19 ENST00000238788.9
ENST00000404032.3
TMEM214
transmembrane protein 214
chr14_-_23834411 1.17 ENST00000429593.2
EFS
embryonal Fyn-associated substrate
chr22_+_38864041 1.15 ENST00000216014.4
ENST00000409006.3
KDELR3
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr19_-_49015050 1.13 ENST00000600059.1
LMTK3
lemur tyrosine kinase 3
chr19_+_17186577 1.11 ENST00000595618.1
ENST00000594824.1
MYO9B
myosin IXB
chr12_-_133405288 1.11 ENST00000204726.3
GOLGA3
golgin A3
chr1_+_6845384 1.10 ENST00000303635.7
CAMTA1
calmodulin binding transcription activator 1
chr3_-_150264272 1.10 ENST00000491660.1
ENST00000487153.1
ENST00000239944.2
SERP1
stress-associated endoplasmic reticulum protein 1
chr9_+_114393581 1.08 ENST00000313525.3
DNAJC25
DnaJ (Hsp40) homolog, subfamily C , member 25
chr16_+_56965960 1.06 ENST00000439977.2
ENST00000344114.4
ENST00000300302.5
ENST00000379792.2
HERPUD1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr12_+_58120044 1.04 ENST00000542466.2
AGAP2-AS1
AGAP2 antisense RNA 1
chr22_-_43253189 1.02 ENST00000437119.2
ENST00000429508.2
ENST00000454099.1
ENST00000263245.5
ARFGAP3
ADP-ribosylation factor GTPase activating protein 3
chr3_+_171758344 1.02 ENST00000336824.4
ENST00000423424.1
FNDC3B
fibronectin type III domain containing 3B
chr3_-_128369643 0.98 ENST00000296255.3
RPN1
ribophorin I
chr4_-_47916613 0.96 ENST00000381538.3
ENST00000329043.3
NFXL1
nuclear transcription factor, X-box binding-like 1
chr11_-_66056596 0.94 ENST00000471387.2
ENST00000359461.6
ENST00000376901.4
YIF1A
Yip1 interacting factor homolog A (S. cerevisiae)
chr9_+_37079888 0.93 ENST00000429493.1
ENST00000593237.1
ENST00000588557.1
ENST00000430809.1
ENST00000592157.1
RP11-220I1.1
RP11-220I1.1
chr2_+_64681219 0.93 ENST00000238875.5
LGALSL
lectin, galactoside-binding-like
chr3_-_57583130 0.92 ENST00000303436.6
ARF4
ADP-ribosylation factor 4
chr7_+_72848092 0.92 ENST00000344575.3
FZD9
frizzled family receptor 9
chr4_-_47916543 0.90 ENST00000507489.1
NFXL1
nuclear transcription factor, X-box binding-like 1
chr8_-_124054587 0.90 ENST00000259512.4
DERL1
derlin 1
chr19_-_10426663 0.90 ENST00000541276.1
ENST00000393708.3
ENST00000494368.1
FDX1L
ferredoxin 1-like
chr12_-_106641728 0.89 ENST00000378026.4
CKAP4
cytoskeleton-associated protein 4
chr20_+_32951041 0.89 ENST00000374864.4
ITCH
itchy E3 ubiquitin protein ligase
chr11_+_65292884 0.87 ENST00000527009.1
SCYL1
SCY1-like 1 (S. cerevisiae)
chr14_+_102430855 0.87 ENST00000360184.4
DYNC1H1
dynein, cytoplasmic 1, heavy chain 1
chr10_+_89419370 0.84 ENST00000361175.4
ENST00000456849.1
PAPSS2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr4_+_128982490 0.84 ENST00000394288.3
ENST00000432347.2
ENST00000264584.5
ENST00000441387.1
ENST00000427266.1
ENST00000354456.3
LARP1B
La ribonucleoprotein domain family, member 1B
chr19_-_47104118 0.83 ENST00000593888.1
ENST00000602017.1
AC011551.3
PPP5D1
Uncharacterized protein
PPP5 tetratricopeptide repeat domain containing 1
chr17_+_64298944 0.82 ENST00000413366.3
PRKCA
protein kinase C, alpha
chr11_+_65819802 0.81 ENST00000528302.1
ENST00000322535.6
ENST00000524627.1
ENST00000533595.1
ENST00000530322.1
SF3B2
splicing factor 3b, subunit 2, 145kDa
chr5_-_2751762 0.81 ENST00000302057.5
ENST00000382611.6
IRX2
iroquois homeobox 2
chr11_-_66056478 0.79 ENST00000431556.2
ENST00000528575.1
YIF1A
Yip1 interacting factor homolog A (S. cerevisiae)
chr20_-_8000426 0.78 ENST00000527925.1
ENST00000246024.2
TMX4
thioredoxin-related transmembrane protein 4
chr2_-_118771701 0.77 ENST00000376300.2
ENST00000319432.5
CCDC93
coiled-coil domain containing 93
chr2_-_88927092 0.75 ENST00000303236.3
EIF2AK3
eukaryotic translation initiation factor 2-alpha kinase 3
chr10_-_22292675 0.75 ENST00000376946.1
DNAJC1
DnaJ (Hsp40) homolog, subfamily C, member 1
chr3_-_57583052 0.73 ENST00000496292.1
ENST00000489843.1
ARF4
ADP-ribosylation factor 4
chr19_-_4670345 0.72 ENST00000599630.1
ENST00000262947.3
C19orf10
chromosome 19 open reading frame 10
chr7_-_6523688 0.71 ENST00000490996.1
KDELR2
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr11_+_65292538 0.71 ENST00000270176.5
ENST00000525364.1
ENST00000420247.2
ENST00000533862.1
ENST00000279270.6
ENST00000524944.1
SCYL1
SCY1-like 1 (S. cerevisiae)
chr5_+_112196919 0.71 ENST00000505459.1
ENST00000282999.3
ENST00000515463.1
SRP19
signal recognition particle 19kDa
chr5_-_176730676 0.70 ENST00000393611.2
ENST00000303251.6
ENST00000303270.6
RAB24
RAB24, member RAS oncogene family
chr17_-_74068567 0.70 ENST00000355113.5
ENST00000539137.1
SRP68
signal recognition particle 68kDa
chr17_-_74068707 0.69 ENST00000307877.2
SRP68
signal recognition particle 68kDa
chr16_-_66959429 0.68 ENST00000420652.1
ENST00000299759.6
RRAD
Ras-related associated with diabetes
chr19_+_39421556 0.67 ENST00000407800.2
ENST00000402029.3
MRPS12
mitochondrial ribosomal protein S12
chr3_-_10362725 0.66 ENST00000397109.3
ENST00000428626.1
ENST00000445064.1
ENST00000431352.1
ENST00000397117.1
ENST00000337354.4
ENST00000383801.2
ENST00000432213.1
ENST00000350697.3
SEC13
SEC13 homolog (S. cerevisiae)
chr20_-_17662878 0.66 ENST00000377813.1
ENST00000377807.2
ENST00000360807.4
ENST00000398782.2
RRBP1
ribosome binding protein 1
chr6_-_34664612 0.66 ENST00000374023.3
ENST00000374026.3
C6orf106
chromosome 6 open reading frame 106
chr19_-_58459039 0.64 ENST00000282308.3
ENST00000598928.1
ZNF256
zinc finger protein 256
chr20_-_17662705 0.64 ENST00000455029.2
RRBP1
ribosome binding protein 1
chr6_-_108279369 0.63 ENST00000369002.4
SEC63
SEC63 homolog (S. cerevisiae)
chr8_-_124054362 0.63 ENST00000405944.3
DERL1
derlin 1
chr4_+_40058411 0.61 ENST00000261435.6
ENST00000515550.1
N4BP2
NEDD4 binding protein 2
chr8_-_124054484 0.61 ENST00000419562.2
DERL1
derlin 1
chr4_-_159644507 0.61 ENST00000307720.3
PPID
peptidylprolyl isomerase D
chr16_+_2479390 0.61 ENST00000397066.4
CCNF
cyclin F
chr2_-_99952769 0.61 ENST00000409434.1
ENST00000434323.1
ENST00000264255.3
TXNDC9
thioredoxin domain containing 9
chr13_-_53313905 0.60 ENST00000377962.3
ENST00000448904.2
LECT1
leukocyte cell derived chemotaxin 1
chr14_-_24664540 0.57 ENST00000530563.1
ENST00000528895.1
ENST00000528669.1
ENST00000532632.1
TM9SF1
transmembrane 9 superfamily member 1
chr4_+_165675197 0.57 ENST00000515485.1
RP11-294O2.2
RP11-294O2.2
chr19_-_19030157 0.56 ENST00000349893.4
ENST00000351079.4
ENST00000600932.1
ENST00000262812.4
COPE
coatomer protein complex, subunit epsilon
chr14_-_24664776 0.55 ENST00000530468.1
ENST00000528010.1
ENST00000396854.4
ENST00000524835.1
ENST00000261789.4
ENST00000525592.1
TM9SF1
transmembrane 9 superfamily member 1
chr9_-_34523027 0.54 ENST00000399775.2
ENHO
energy homeostasis associated
chr4_+_26322409 0.54 ENST00000514807.1
ENST00000348160.4
ENST00000509158.1
ENST00000355476.3
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr7_-_128045984 0.54 ENST00000470772.1
ENST00000480861.1
ENST00000496200.1
IMPDH1
IMP (inosine 5'-monophosphate) dehydrogenase 1
chr19_+_19030478 0.53 ENST00000247003.4
DDX49
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chr11_+_64851666 0.53 ENST00000525509.1
ENST00000294258.3
ENST00000526334.1
ZFPL1
zinc finger protein-like 1
chr2_+_220408724 0.53 ENST00000421791.1
ENST00000373883.3
ENST00000451952.1
TMEM198
transmembrane protein 198
chr11_-_118927816 0.52 ENST00000534233.1
ENST00000532752.1
ENST00000525859.1
ENST00000404233.3
ENST00000532421.1
ENST00000543287.1
ENST00000527310.2
ENST00000529972.1
HYOU1
hypoxia up-regulated 1
chr9_-_112260531 0.52 ENST00000374541.2
ENST00000262539.3
PTPN3
protein tyrosine phosphatase, non-receptor type 3
chr4_+_128982430 0.52 ENST00000512292.1
ENST00000508819.1
LARP1B
La ribonucleoprotein domain family, member 1B
chr6_-_7313381 0.51 ENST00000489567.1
ENST00000479365.1
ENST00000462112.1
ENST00000397511.2
ENST00000534851.1
ENST00000474597.1
ENST00000244763.4
SSR1
signal sequence receptor, alpha
chr6_+_7107999 0.51 ENST00000491191.1
ENST00000379938.2
ENST00000471433.1
RREB1
ras responsive element binding protein 1
chr10_-_128077024 0.51 ENST00000368679.4
ENST00000368676.4
ENST00000448723.1
ADAM12
ADAM metallopeptidase domain 12
chr19_+_19030497 0.50 ENST00000438170.2
DDX49
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chr19_+_33182823 0.49 ENST00000397061.3
NUDT19
nudix (nucleoside diphosphate linked moiety X)-type motif 19
chr5_-_115177496 0.49 ENST00000274459.4
ENST00000509910.1
ATG12
autophagy related 12
chr18_+_34409069 0.49 ENST00000543923.1
ENST00000280020.5
ENST00000435985.2
ENST00000592521.1
ENST00000587139.1
KIAA1328
KIAA1328
chr5_-_108745689 0.48 ENST00000361189.2
PJA2
praja ring finger 2, E3 ubiquitin protein ligase
chr13_+_26042960 0.48 ENST00000255283.8
ATP8A2
ATPase, aminophospholipid transporter, class I, type 8A, member 2
chr10_+_104678102 0.48 ENST00000433628.2
CNNM2
cyclin M2
chr8_+_56014949 0.46 ENST00000327381.6
XKR4
XK, Kell blood group complex subunit-related family, member 4
chr1_-_28241024 0.44 ENST00000313433.7
ENST00000444045.1
RPA2
replication protein A2, 32kDa
chr1_+_145575980 0.43 ENST00000393045.2
PIAS3
protein inhibitor of activated STAT, 3
chr2_-_242254595 0.43 ENST00000441124.1
ENST00000391976.2
HDLBP
high density lipoprotein binding protein
chr12_-_99038732 0.43 ENST00000393042.3
ENST00000420861.1
ENST00000299157.4
ENST00000342502.2
IKBIP
IKBKB interacting protein
chr19_-_39523165 0.43 ENST00000509137.2
ENST00000292853.4
FBXO27
F-box protein 27
chr1_+_145576007 0.42 ENST00000369298.1
PIAS3
protein inhibitor of activated STAT, 3
chr15_+_79603404 0.42 ENST00000299705.5
TMED3
transmembrane emp24 protein transport domain containing 3
chr4_+_56262115 0.42 ENST00000506198.1
ENST00000381334.5
ENST00000542052.1
TMEM165
transmembrane protein 165
chr19_+_16187816 0.41 ENST00000588410.1
TPM4
tropomyosin 4
chr11_-_40315640 0.41 ENST00000278198.2
LRRC4C
leucine rich repeat containing 4C
chr4_+_76649797 0.41 ENST00000538159.1
ENST00000514213.2
USO1
USO1 vesicle transport factor
chr16_-_75569068 0.41 ENST00000336257.3
ENST00000565039.1
CHST5
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
chr9_+_126777676 0.40 ENST00000488674.2
LHX2
LIM homeobox 2
chr10_+_32735030 0.40 ENST00000277657.6
ENST00000362006.5
CCDC7
coiled-coil domain containing 7
chr11_+_47430133 0.39 ENST00000531974.1
ENST00000531419.1
ENST00000531865.1
ENST00000362021.4
ENST00000354884.4
SLC39A13
solute carrier family 39 (zinc transporter), member 13
chr12_-_28122980 0.38 ENST00000395868.3
ENST00000534890.1
PTHLH
parathyroid hormone-like hormone
chr4_+_26322185 0.37 ENST00000361572.6
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr22_-_20850070 0.37 ENST00000440659.2
ENST00000458248.1
ENST00000443285.1
ENST00000444967.1
ENST00000451553.1
ENST00000431430.1
KLHL22
kelch-like family member 22
chr4_-_83350580 0.37 ENST00000349655.4
ENST00000602300.1
HNRNPDL
heterogeneous nuclear ribonucleoprotein D-like
chr22_-_20850128 0.35 ENST00000328879.4
KLHL22
kelch-like family member 22
chr7_-_6523755 0.35 ENST00000436575.1
ENST00000258739.4
DAGLB
KDELR2
diacylglycerol lipase, beta
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr3_+_50284321 0.34 ENST00000451956.1
GNAI2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr6_+_132129151 0.33 ENST00000360971.2
ENPP1
ectonucleotide pyrophosphatase/phosphodiesterase 1
chr10_+_64893039 0.33 ENST00000277746.6
ENST00000435510.2
NRBF2
nuclear receptor binding factor 2
chr11_+_118443098 0.32 ENST00000392859.3
ENST00000359415.4
ENST00000534182.2
ENST00000264028.4
ARCN1
archain 1
chr10_+_104678032 0.31 ENST00000369878.4
ENST00000369875.3
CNNM2
cyclin M2
chr1_+_63788730 0.30 ENST00000371116.2
FOXD3
forkhead box D3
chr19_-_8373173 0.30 ENST00000537716.2
ENST00000301458.5
CD320
CD320 molecule
chr9_+_101984577 0.30 ENST00000223641.4
SEC61B
Sec61 beta subunit
chr8_+_105235572 0.29 ENST00000523362.1
RIMS2
regulating synaptic membrane exocytosis 2
chr12_-_28123206 0.28 ENST00000542963.1
ENST00000535992.1
PTHLH
parathyroid hormone-like hormone
chr1_+_207669573 0.28 ENST00000400960.2
ENST00000534202.1
CR1
complement component (3b/4b) receptor 1 (Knops blood group)
chr6_+_7108210 0.27 ENST00000467782.1
ENST00000334984.6
ENST00000349384.6
RREB1
ras responsive element binding protein 1
chr3_-_132378897 0.26 ENST00000545291.1
ACAD11
acyl-CoA dehydrogenase family, member 11
chr22_+_46476192 0.25 ENST00000443490.1
FLJ27365
hsa-mir-4763
chr1_+_228270361 0.25 ENST00000272102.5
ENST00000540651.1
ARF1
ADP-ribosylation factor 1
chr1_+_110527308 0.24 ENST00000369799.5
AHCYL1
adenosylhomocysteinase-like 1
chr7_+_6522922 0.24 ENST00000601673.1
FLJ20306
CDNA FLJ20306 fis, clone HEP06881; Putative uncharacterized protein FLJ20306; Uncharacterized protein
chr5_-_60458179 0.22 ENST00000507416.1
ENST00000339020.3
SMIM15
small integral membrane protein 15
chr7_-_19157248 0.22 ENST00000242261.5
TWIST1
twist family bHLH transcription factor 1
chr11_-_68039364 0.22 ENST00000533310.1
ENST00000304271.6
ENST00000527280.1
C11orf24
chromosome 11 open reading frame 24
chr11_-_118972575 0.19 ENST00000432443.2
DPAGT1
dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr19_-_4066890 0.18 ENST00000322357.4
ZBTB7A
zinc finger and BTB domain containing 7A
chrX_-_153059811 0.17 ENST00000427365.2
ENST00000444450.1
ENST00000370093.1
IDH3G
isocitrate dehydrogenase 3 (NAD+) gamma
chr6_+_7107830 0.17 ENST00000379933.3
RREB1
ras responsive element binding protein 1
chr19_-_22379753 0.17 ENST00000397121.2
ZNF676
zinc finger protein 676
chr1_-_161087802 0.16 ENST00000368010.3
PFDN2
prefoldin subunit 2
chrX_+_47050236 0.15 ENST00000377351.4
UBA1
ubiquitin-like modifier activating enzyme 1
chr10_+_75504105 0.15 ENST00000535742.1
ENST00000546025.1
ENST00000345254.4
ENST00000540668.1
ENST00000339365.2
ENST00000411652.2
SEC24C
SEC24 family member C
chr8_-_38126675 0.15 ENST00000531823.1
ENST00000534339.1
ENST00000524616.1
ENST00000422581.2
ENST00000424479.2
ENST00000419686.2
PPAPDC1B
phosphatidic acid phosphatase type 2 domain containing 1B
chr2_+_85132749 0.15 ENST00000233143.4
TMSB10
thymosin beta 10
chr15_-_75165651 0.14 ENST00000562363.1
ENST00000564529.1
ENST00000268099.9
SCAMP2
secretory carrier membrane protein 2
chr1_-_119682812 0.14 ENST00000537870.1
WARS2
tryptophanyl tRNA synthetase 2, mitochondrial
chr19_+_1491144 0.14 ENST00000233596.3
REEP6
receptor accessory protein 6
chr7_+_116593953 0.12 ENST00000397750.3
ST7-OT4
ST7 overlapping transcript 4
chr2_+_242254679 0.12 ENST00000428282.1
ENST00000360051.3
SEPT2
septin 2
chr9_+_124461603 0.12 ENST00000373782.3
DAB2IP
DAB2 interacting protein
chr2_+_242254507 0.12 ENST00000391973.2
SEPT2
septin 2
chr14_+_39736299 0.11 ENST00000341502.5
ENST00000396158.2
ENST00000280083.3
CTAGE5
CTAGE family, member 5

Network of associatons between targets according to the STRING database.

First level regulatory network of XBP1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.2 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.5 1.6 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.5 1.5 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.5 3.2 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.5 1.4 GO:0039019 pronephric nephron development(GO:0039019)
0.5 2.3 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.4 2.2 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913) protein K29-linked ubiquitination(GO:0035519)
0.4 2.4 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.4 5.0 GO:0048251 elastic fiber assembly(GO:0048251)
0.4 4.0 GO:0070141 response to UV-A(GO:0070141)
0.4 3.6 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.4 2.1 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.3 2.4 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.3 0.9 GO:1904397 negative regulation of neuromuscular junction development(GO:1904397)
0.3 0.9 GO:1901297 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.3 2.1 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.3 1.5 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.3 0.8 GO:0061110 histone H3-T6 phosphorylation(GO:0035408) dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.3 2.9 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.3 2.6 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.2 0.7 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.2 2.7 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.2 0.9 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.2 0.7 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.2 0.8 GO:0000103 sulfate assimilation(GO:0000103)
0.2 0.8 GO:0072086 specification of loop of Henle identity(GO:0072086) pattern specification involved in metanephros development(GO:0072268)
0.2 2.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.2 1.9 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.2 0.9 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.2 1.3 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.2 0.7 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 1.7 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 0.9 GO:0090235 regulation of metaphase plate congression(GO:0090235)
0.1 3.0 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 1.1 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.1 0.4 GO:0030451 regulation of complement activation, alternative pathway(GO:0030451) negative regulation of complement activation, alternative pathway(GO:0045957)
0.1 0.6 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1 4.0 GO:0048846 axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284)
0.1 0.3 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 3.0 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 1.5 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.1 3.1 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 0.5 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 0.2 GO:0097212 cleavage furrow ingression(GO:0036090) lysosomal membrane organization(GO:0097212) positive regulation of late endosome to lysosome transport(GO:1902824) positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
0.1 0.3 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.1 0.2 GO:2000793 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276) cell proliferation involved in heart valve development(GO:2000793)
0.1 1.6 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 1.6 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.1 6.2 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1 0.3 GO:0031296 B cell costimulation(GO:0031296)
0.1 0.4 GO:0032472 Golgi calcium ion transport(GO:0032472)
0.1 1.1 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.1 0.5 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.9 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.1 1.2 GO:0044126 regulation of growth of symbiont in host(GO:0044126)
0.0 0.4 GO:0006477 protein sulfation(GO:0006477)
0.0 1.5 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.6 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 3.4 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.0 0.2 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.3 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.6 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
0.0 0.1 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.4 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.0 0.7 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 1.9 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.4 GO:0021978 telencephalon regionalization(GO:0021978)
0.0 0.2 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.4 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 1.0 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.5 GO:0044804 nucleophagy(GO:0044804)
0.0 1.0 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.7 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.7 GO:0071173 mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173)
0.0 0.3 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.1 GO:0035459 cargo loading into vesicle(GO:0035459)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.8 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 0.5 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.5 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 1.1 GO:0010923 negative regulation of phosphatase activity(GO:0010923)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.5 2.1 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.4 2.1 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.2 2.5 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.2 2.8 GO:0030126 COPI vesicle coat(GO:0030126)
0.2 2.1 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.2 4.1 GO:0030127 COPII vesicle coat(GO:0030127)
0.2 0.9 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.2 1.1 GO:1990037 Lewy body core(GO:1990037)
0.1 0.7 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.1 0.5 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.1 0.7 GO:0005827 polar microtubule(GO:0005827)
0.1 2.6 GO:0042101 T cell receptor complex(GO:0042101)
0.1 1.1 GO:0017119 Golgi transport complex(GO:0017119)
0.1 0.3 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.1 1.0 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 3.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.3 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 2.9 GO:0031201 SNARE complex(GO:0031201)
0.0 0.1 GO:1990032 parallel fiber(GO:1990032)
0.0 0.9 GO:0042599 lamellar body(GO:0042599)
0.0 2.5 GO:0031228 intrinsic component of Golgi membrane(GO:0031228)
0.0 1.7 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.8 GO:0005686 U2 snRNP(GO:0005686)
0.0 1.1 GO:0000421 autophagosome membrane(GO:0000421)
0.0 2.3 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.9 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.7 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.9 GO:0031527 filopodium membrane(GO:0031527)
0.0 3.0 GO:0005581 collagen trimer(GO:0005581)
0.0 1.6 GO:0002102 podosome(GO:0002102)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.7 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 2.7 GO:0032587 ruffle membrane(GO:0032587)
0.0 3.2 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 1.1 GO:0016459 myosin complex(GO:0016459)
0.0 7.2 GO:0030016 myofibril(GO:0030016)
0.0 15.1 GO:0000139 Golgi membrane(GO:0000139)
0.0 1.9 GO:0005796 Golgi lumen(GO:0005796)
0.0 1.4 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 1.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.2 GO:0097227 sperm annulus(GO:0097227)
0.0 0.1 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 1.3 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.7 GO:0005776 autophagosome(GO:0005776)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.0 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.8 2.4 GO:0004766 spermidine synthase activity(GO:0004766)
0.6 3.0 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.5 1.6 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.5 1.5 GO:0008478 pyridoxal kinase activity(GO:0008478) lithium ion binding(GO:0031403)
0.4 2.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.3 1.4 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.3 2.3 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.3 1.9 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.3 0.8 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.3 2.2 GO:0046923 ER retention sequence binding(GO:0046923)
0.3 0.8 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.3 1.3 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.2 1.4 GO:0005047 signal recognition particle binding(GO:0005047)
0.2 0.7 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.2 4.2 GO:0035497 cAMP response element binding(GO:0035497)
0.2 5.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.2 0.6 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1 2.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.5 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 1.2 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.4 GO:0004877 complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877)
0.1 1.1 GO:0048495 Roundabout binding(GO:0048495)
0.1 3.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 4.1 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 3.4 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.7 GO:0008312 7S RNA binding(GO:0008312)
0.1 0.6 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 0.3 GO:0015235 cobalamin transporter activity(GO:0015235)
0.1 2.1 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.1 2.7 GO:0008483 transaminase activity(GO:0008483)
0.1 1.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.5 GO:0019776 Atg8 ligase activity(GO:0019776)
0.1 3.1 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 0.9 GO:0000150 recombinase activity(GO:0000150)
0.1 1.0 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 0.3 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 3.2 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 0.4 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 1.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.2 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 1.5 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.6 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.2 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.2 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.9 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 1.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.4 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 2.6 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 1.0 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.8 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.1 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 1.5 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.5 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.5 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 1.6 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.7 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 2.5 GO:0008276 protein methyltransferase activity(GO:0008276)
0.0 1.4 GO:0043022 ribosome binding(GO:0043022)
0.0 0.7 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 2.5 GO:0000149 SNARE binding(GO:0000149)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.2 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 1.6 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.3 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.3 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.9 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 1.0 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 2.3 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 2.1 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 4.2 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 4.1 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 4.0 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 0.9 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.8 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 3.7 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.3 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.7 PID ARF 3PATHWAY Arf1 pathway
0.0 0.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 2.9 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 4.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.5 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 4.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.7 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 4.3 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 2.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 4.1 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 1.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 6.8 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 2.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 0.8 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 1.7 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 1.6 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1 1.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.2 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 2.1 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 1.7 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.0 0.8 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.4 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 1.2 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 2.1 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 3.1 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 4.4 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 1.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.3 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 2.6 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.4 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.2 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.8 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 1.6 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 2.1 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.9 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation