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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for ZBTB12

Z-value: 0.54

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Transcription factors associated with ZBTB12

Gene Symbol Gene ID Gene Info
ZBTB12
ENSG00000204366.3 zinc finger and BTB domain containing 12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZBTB12hg19_v2_chr6_-_31869769_31869880-0.301.4e-01Click!

Activity profile of ZBTB12 motif

Sorted Z-values of ZBTB12 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_61869748 2.08 ENST00000357977.5
NFIA
nuclear factor I/A
chr14_-_91526462 2.04 ENST00000536315.2
RPS6KA5
ribosomal protein S6 kinase, 90kDa, polypeptide 5
chr1_+_158979686 0.79 ENST00000368132.3
ENST00000295809.7
IFI16
interferon, gamma-inducible protein 16
chr1_+_158979680 0.78 ENST00000368131.4
ENST00000340979.6
IFI16
interferon, gamma-inducible protein 16
chr1_+_158979792 0.78 ENST00000359709.3
ENST00000430894.2
IFI16
interferon, gamma-inducible protein 16
chr5_-_88179302 0.78 ENST00000504921.2
MEF2C
myocyte enhancer factor 2C
chr6_+_147527103 0.75 ENST00000179882.6
STXBP5
syntaxin binding protein 5 (tomosyn)
chr3_-_149051444 0.73 ENST00000296059.2
TM4SF18
transmembrane 4 L six family member 18
chr6_+_18387570 0.68 ENST00000259939.3
RNF144B
ring finger protein 144B
chr5_-_88178964 0.65 ENST00000513252.1
ENST00000508569.1
ENST00000510942.1
ENST00000506554.1
MEF2C
myocyte enhancer factor 2C
chr1_+_84873913 0.63 ENST00000370662.3
DNASE2B
deoxyribonuclease II beta
chr12_-_46766577 0.62 ENST00000256689.5
SLC38A2
solute carrier family 38, member 2
chr5_-_88179017 0.60 ENST00000514028.1
ENST00000514015.1
ENST00000503075.1
ENST00000437473.2
MEF2C
myocyte enhancer factor 2C
chr3_-_164875850 0.59 ENST00000472120.1
RP11-747D18.1
RP11-747D18.1
chr3_-_149051194 0.59 ENST00000470080.1
TM4SF18
transmembrane 4 L six family member 18
chr14_-_21270995 0.58 ENST00000555698.1
ENST00000397970.4
ENST00000340900.3
RNASE1
ribonuclease, RNase A family, 1 (pancreatic)
chr9_-_80437915 0.56 ENST00000397476.3
GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
chr1_+_32757668 0.53 ENST00000373548.3
HDAC1
histone deacetylase 1
chr2_+_190722119 0.53 ENST00000452382.1
PMS1
PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
chr7_-_93520191 0.51 ENST00000545378.1
TFPI2
tissue factor pathway inhibitor 2
chr19_+_55417499 0.51 ENST00000291890.4
ENST00000447255.1
ENST00000598576.1
ENST00000594765.1
NCR1
natural cytotoxicity triggering receptor 1
chr2_+_89999259 0.49 ENST00000558026.1
IGKV2D-28
immunoglobulin kappa variable 2D-28
chr8_+_118533049 0.48 ENST00000522839.1
MED30
mediator complex subunit 30
chr8_+_1993152 0.47 ENST00000262113.4
MYOM2
myomesin 2
chr17_-_39677971 0.47 ENST00000393976.2
KRT15
keratin 15
chr10_+_5454505 0.47 ENST00000355029.4
NET1
neuroepithelial cell transforming 1
chr17_-_5487768 0.45 ENST00000269280.4
ENST00000345221.3
ENST00000262467.5
NLRP1
NLR family, pyrin domain containing 1
chr8_+_118532937 0.45 ENST00000297347.3
MED30
mediator complex subunit 30
chrX_-_133931164 0.44 ENST00000370790.1
ENST00000298090.6
FAM122B
family with sequence similarity 122B
chrX_-_73072534 0.43 ENST00000429829.1
XIST
X inactive specific transcript (non-protein coding)
chr1_+_46049706 0.39 ENST00000527470.1
ENST00000525515.1
ENST00000537798.1
ENST00000402363.3
ENST00000528238.1
ENST00000350030.3
ENST00000470768.1
ENST00000372052.4
ENST00000351223.3
NASP
nuclear autoantigenic sperm protein (histone-binding)
chr17_+_4643337 0.38 ENST00000592813.1
ZMYND15
zinc finger, MYND-type containing 15
chr20_-_36793663 0.38 ENST00000536701.1
ENST00000536724.1
TGM2
transglutaminase 2
chr9_+_127615733 0.37 ENST00000373574.1
WDR38
WD repeat domain 38
chrX_+_70338525 0.36 ENST00000374102.1
MED12
mediator complex subunit 12
chr8_+_1993173 0.36 ENST00000523438.1
MYOM2
myomesin 2
chr19_+_55417530 0.34 ENST00000350790.5
ENST00000338835.5
ENST00000357397.5
NCR1
natural cytotoxicity triggering receptor 1
chr6_+_2988847 0.34 ENST00000380472.3
ENST00000605901.1
ENST00000454015.1
NQO2
LINC01011
NAD(P)H dehydrogenase, quinone 2
long intergenic non-protein coding RNA 1011
chr11_-_2170786 0.30 ENST00000300632.5
IGF2
insulin-like growth factor 2 (somatomedin A)
chr7_-_93520259 0.30 ENST00000222543.5
TFPI2
tissue factor pathway inhibitor 2
chr5_-_38557561 0.29 ENST00000511561.1
LIFR
leukemia inhibitory factor receptor alpha
chr13_-_37633743 0.29 ENST00000497318.1
ENST00000475892.1
ENST00000356185.3
ENST00000350612.6
ENST00000542180.1
ENST00000360252.4
SUPT20H
suppressor of Ty 20 homolog (S. cerevisiae)
chr18_-_53177984 0.29 ENST00000543082.1
TCF4
transcription factor 4
chr11_+_63449045 0.28 ENST00000354497.4
RTN3
reticulon 3
chr3_-_114343039 0.25 ENST00000481632.1
ZBTB20
zinc finger and BTB domain containing 20
chr5_-_148929848 0.25 ENST00000504676.1
ENST00000515435.1
CSNK1A1
casein kinase 1, alpha 1
chr1_+_201755452 0.24 ENST00000438083.1
NAV1
neuron navigator 1
chr12_-_11214893 0.24 ENST00000533467.1
TAS2R46
taste receptor, type 2, member 46
chr15_-_34880646 0.24 ENST00000543376.1
GOLGA8A
golgin A8 family, member A
chr19_-_11688500 0.23 ENST00000433365.2
ACP5
acid phosphatase 5, tartrate resistant
chr11_+_112047087 0.22 ENST00000526088.1
ENST00000532593.1
ENST00000531169.1
BCO2
beta-carotene oxygenase 2
chr17_-_46178527 0.22 ENST00000393408.3
CBX1
chromobox homolog 1
chr18_-_24445664 0.21 ENST00000578776.1
AQP4
aquaporin 4
chr20_-_25320367 0.21 ENST00000450393.1
ENST00000491682.1
ABHD12
abhydrolase domain containing 12
chrX_-_24690771 0.20 ENST00000379145.1
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr14_-_50154921 0.20 ENST00000553805.2
ENST00000554396.1
ENST00000216367.5
ENST00000539565.2
POLE2
polymerase (DNA directed), epsilon 2, accessory subunit
chr19_-_46148820 0.20 ENST00000587152.1
EML2
echinoderm microtubule associated protein like 2
chr12_-_58329819 0.19 ENST00000551421.1
RP11-620J15.3
RP11-620J15.3
chr2_+_173600514 0.19 ENST00000264111.6
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr14_-_54908043 0.18 ENST00000556113.1
ENST00000553660.1
ENST00000395573.4
ENST00000557690.1
ENST00000216416.4
CNIH1
cornichon family AMPA receptor auxiliary protein 1
chr11_-_59952106 0.17 ENST00000529054.1
ENST00000530839.1
MS4A6A
membrane-spanning 4-domains, subfamily A, member 6A
chr6_-_170599561 0.17 ENST00000366756.3
DLL1
delta-like 1 (Drosophila)
chr11_+_12132117 0.16 ENST00000256194.4
MICAL2
microtubule associated monooxygenase, calponin and LIM domain containing 2
chr14_-_70826438 0.16 ENST00000389912.6
COX16
COX16 cytochrome c oxidase assembly homolog (S. cerevisiae)
chr10_+_23217006 0.15 ENST00000376528.4
ENST00000447081.1
ARMC3
armadillo repeat containing 3
chr7_-_142139783 0.15 ENST00000390374.3
TRBV7-6
T cell receptor beta variable 7-6
chr10_+_23216944 0.15 ENST00000298032.5
ENST00000409983.3
ENST00000409049.3
ARMC3
armadillo repeat containing 3
chr14_-_22938665 0.15 ENST00000535880.2
TRDV3
T cell receptor delta variable 3
chr12_-_58329888 0.14 ENST00000546580.1
RP11-620J15.3
RP11-620J15.3
chr3_+_101818088 0.14 ENST00000491959.1
ZPLD1
zona pellucida-like domain containing 1
chr5_-_122372354 0.14 ENST00000306442.4
PPIC
peptidylprolyl isomerase C (cyclophilin C)
chr19_+_46195895 0.14 ENST00000366382.4
QPCTL
glutaminyl-peptide cyclotransferase-like
chr22_-_42084863 0.13 ENST00000401959.1
ENST00000355257.3
NHP2L1
NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)
chr12_+_53689309 0.13 ENST00000351500.3
ENST00000550846.1
ENST00000334478.4
ENST00000549759.1
PFDN5
prefoldin subunit 5
chr17_-_61781750 0.13 ENST00000582026.1
STRADA
STE20-related kinase adaptor alpha
chr12_+_123459127 0.13 ENST00000397389.2
ENST00000538755.1
ENST00000536150.1
ENST00000545056.1
ENST00000545612.1
ENST00000538628.1
ENST00000545317.1
OGFOD2
2-oxoglutarate and iron-dependent oxygenase domain containing 2
chr2_+_234545092 0.13 ENST00000344644.5
UGT1A10
UDP glucuronosyltransferase 1 family, polypeptide A10
chr1_-_109203997 0.12 ENST00000370032.5
HENMT1
HEN1 methyltransferase homolog 1 (Arabidopsis)
chr11_-_101000445 0.11 ENST00000534013.1
PGR
progesterone receptor
chr6_+_36097992 0.11 ENST00000211287.4
MAPK13
mitogen-activated protein kinase 13
chr19_-_51531210 0.11 ENST00000391804.3
KLK11
kallikrein-related peptidase 11
chr1_-_198990166 0.10 ENST00000427439.1
RP11-16L9.3
RP11-16L9.3
chr11_+_60145948 0.10 ENST00000300184.3
ENST00000358246.1
MS4A7
membrane-spanning 4-domains, subfamily A, member 7
chr20_-_33543546 0.10 ENST00000216951.2
GSS
glutathione synthetase
chr3_+_26735991 0.10 ENST00000456208.2
LRRC3B
leucine rich repeat containing 3B
chr10_+_180405 0.09 ENST00000439456.1
ENST00000397962.3
ENST00000309776.4
ENST00000381602.4
ZMYND11
zinc finger, MYND-type containing 11
chr1_+_22778337 0.09 ENST00000404138.1
ENST00000400239.2
ENST00000375647.4
ENST00000374651.4
ZBTB40
zinc finger and BTB domain containing 40
chr7_-_138347897 0.09 ENST00000288513.5
SVOPL
SVOP-like
chr1_+_158901329 0.09 ENST00000368140.1
ENST00000368138.3
ENST00000392254.2
ENST00000392252.3
ENST00000368135.4
PYHIN1
pyrin and HIN domain family, member 1
chr12_+_54378923 0.09 ENST00000303460.4
HOXC10
homeobox C10
chr18_-_32870148 0.08 ENST00000589178.1
ENST00000333206.5
ENST00000592278.1
ENST00000592211.1
ENST00000420878.3
ENST00000383091.2
ENST00000586922.2
ZSCAN30
RP11-158H5.7
zinc finger and SCAN domain containing 30
RP11-158H5.7
chr17_-_27405875 0.08 ENST00000359450.6
TIAF1
TGFB1-induced anti-apoptotic factor 1
chr1_+_100598691 0.08 ENST00000370143.1
ENST00000370141.2
TRMT13
tRNA methyltransferase 13 homolog (S. cerevisiae)
chr14_-_74959978 0.08 ENST00000541064.1
NPC2
Niemann-Pick disease, type C2
chr3_-_151047327 0.07 ENST00000325602.5
P2RY13
purinergic receptor P2Y, G-protein coupled, 13
chr12_+_49121213 0.07 ENST00000548380.1
LINC00935
long intergenic non-protein coding RNA 935
chr22_+_22930626 0.07 ENST00000390302.2
IGLV2-33
immunoglobulin lambda variable 2-33 (non-functional)
chr6_+_26158343 0.07 ENST00000377777.4
ENST00000289316.2
HIST1H2BD
histone cluster 1, H2bd
chr14_-_74959994 0.07 ENST00000238633.2
ENST00000434013.2
NPC2
Niemann-Pick disease, type C2
chr8_+_110098850 0.07 ENST00000518632.1
TRHR
thyrotropin-releasing hormone receptor
chr19_+_11485333 0.07 ENST00000312423.2
SWSAP1
SWIM-type zinc finger 7 associated protein 1
chr10_+_180643 0.07 ENST00000509513.2
ENST00000397959.3
ZMYND11
zinc finger, MYND-type containing 11
chr5_+_148786423 0.07 ENST00000505254.2
ENST00000602964.1
ENST00000519898.1
MIR143HG
MIR143 host gene (non-protein coding)
chr17_+_11501748 0.07 ENST00000262442.4
ENST00000579828.1
DNAH9
dynein, axonemal, heavy chain 9
chr1_+_151009054 0.07 ENST00000295294.7
BNIPL
BCL2/adenovirus E1B 19kD interacting protein like
chr1_+_151009035 0.07 ENST00000368931.3
BNIPL
BCL2/adenovirus E1B 19kD interacting protein like
chr3_+_89156674 0.06 ENST00000336596.2
EPHA3
EPH receptor A3
chr14_-_74960030 0.06 ENST00000553490.1
ENST00000557510.1
NPC2
Niemann-Pick disease, type C2
chr19_-_6767516 0.06 ENST00000245908.6
SH2D3A
SH2 domain containing 3A
chr11_+_74303575 0.06 ENST00000263681.2
POLD3
polymerase (DNA-directed), delta 3, accessory subunit
chr1_+_100503643 0.06 ENST00000370152.3
HIAT1
hippocampus abundant transcript 1
chr4_-_85419603 0.06 ENST00000295886.4
NKX6-1
NK6 homeobox 1
chr7_+_48211048 0.06 ENST00000435803.1
ABCA13
ATP-binding cassette, sub-family A (ABC1), member 13
chr10_-_98273668 0.05 ENST00000357947.3
TLL2
tolloid-like 2
chr7_+_23637763 0.05 ENST00000410069.1
CCDC126
coiled-coil domain containing 126
chr11_+_8704748 0.05 ENST00000526562.1
ENST00000525981.1
RPL27A
ribosomal protein L27a
chr10_+_90660832 0.05 ENST00000371924.1
STAMBPL1
STAM binding protein-like 1
chr7_+_102389434 0.05 ENST00000409231.3
ENST00000418198.1
FAM185A
family with sequence similarity 185, member A
chr11_+_72525353 0.04 ENST00000321297.5
ENST00000534905.1
ENST00000540567.1
ATG16L2
autophagy related 16-like 2 (S. cerevisiae)
chr11_-_59951889 0.04 ENST00000532169.1
ENST00000534596.1
MS4A6A
membrane-spanning 4-domains, subfamily A, member 6A
chr1_+_35220613 0.04 ENST00000338513.1
GJB5
gap junction protein, beta 5, 31.1kDa
chr19_-_6767431 0.04 ENST00000437152.3
ENST00000597687.1
SH2D3A
SH2 domain containing 3A
chr10_+_52152766 0.04 ENST00000596442.1
AC069547.2
Uncharacterized protein
chr1_+_171107241 0.03 ENST00000236166.3
FMO6P
flavin containing monooxygenase 6 pseudogene
chr3_+_89156799 0.03 ENST00000452448.2
ENST00000494014.1
EPHA3
EPH receptor A3
chr4_-_99851766 0.03 ENST00000450253.2
EIF4E
eukaryotic translation initiation factor 4E
chr12_-_56321397 0.03 ENST00000557259.1
ENST00000549939.1
WIBG
within bgcn homolog (Drosophila)
chr9_-_4666421 0.03 ENST00000381895.5
SPATA6L
spermatogenesis associated 6-like
chr11_-_119252359 0.03 ENST00000455332.2
USP2
ubiquitin specific peptidase 2
chr11_+_63273811 0.03 ENST00000340246.5
LGALS12
lectin, galactoside-binding, soluble, 12
chr7_+_129984630 0.03 ENST00000355388.3
ENST00000497503.1
ENST00000463587.1
ENST00000461828.1
ENST00000494311.1
ENST00000466363.2
ENST00000485477.1
ENST00000431780.2
ENST00000474905.1
CPA5
carboxypeptidase A5
chr18_-_47018769 0.03 ENST00000583637.1
ENST00000578528.1
ENST00000578532.1
ENST00000580387.1
ENST00000579248.1
ENST00000581373.1
RPL17
ribosomal protein L17
chr6_+_140175987 0.03 ENST00000414038.1
ENST00000431609.1
RP5-899B16.1
RP5-899B16.1
chr2_+_197577841 0.03 ENST00000409270.1
CCDC150
coiled-coil domain containing 150
chr4_-_36246060 0.03 ENST00000303965.4
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr11_+_60145967 0.02 ENST00000534016.1
MS4A7
membrane-spanning 4-domains, subfamily A, member 7
chr16_+_31724552 0.02 ENST00000539915.1
ENST00000316491.9
ENST00000399681.3
ENST00000398696.3
ENST00000534369.1
ZNF720
zinc finger protein 720
chr9_-_28026318 0.02 ENST00000308675.3
LINGO2
leucine rich repeat and Ig domain containing 2
chr21_-_32253874 0.02 ENST00000332378.4
KRTAP11-1
keratin associated protein 11-1
chr12_+_72080253 0.02 ENST00000549735.1
TMEM19
transmembrane protein 19
chr15_-_66797172 0.02 ENST00000569438.1
ENST00000569696.1
ENST00000307961.6
RPL4
ribosomal protein L4
chrX_-_122866874 0.01 ENST00000245838.8
ENST00000355725.4
THOC2
THO complex 2
chr12_-_123215306 0.01 ENST00000356987.2
ENST00000436083.2
HCAR1
hydroxycarboxylic acid receptor 1
chr7_-_142247606 0.01 ENST00000390361.3
TRBV7-3
T cell receptor beta variable 7-3
chr10_+_63422695 0.01 ENST00000330194.2
ENST00000389639.3
C10orf107
chromosome 10 open reading frame 107
chr22_-_36236623 0.01 ENST00000405409.2
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr5_-_35089722 0.01 ENST00000511486.1
ENST00000310101.5
ENST00000231423.3
ENST00000513753.1
ENST00000348262.3
ENST00000397391.3
ENST00000542609.1
PRLR
prolactin receptor
chr15_+_93015151 0.01 ENST00000556865.1
C15orf32
chromosome 15 open reading frame 32
chr12_-_7077125 0.01 ENST00000545555.2
PHB2
prohibitin 2
chr1_+_46016703 0.01 ENST00000481885.1
ENST00000351829.4
ENST00000471651.1
AKR1A1
aldo-keto reductase family 1, member A1 (aldehyde reductase)
chr12_+_14572070 0.00 ENST00000545769.1
ENST00000428217.2
ENST00000396279.2
ENST00000542514.1
ENST00000536279.1
ATF7IP
activating transcription factor 7 interacting protein
chr16_-_30134524 0.00 ENST00000395202.1
ENST00000395199.3
ENST00000263025.4
ENST00000322266.5
ENST00000403394.1
MAPK3
mitogen-activated protein kinase 3

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB12

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.4 2.0 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.1 0.4 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.1 0.8 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.1 0.5 GO:0061198 fungiform papilla formation(GO:0061198)
0.1 2.1 GO:0072189 ureter development(GO:0072189)
0.1 0.2 GO:0042214 terpene metabolic process(GO:0042214)
0.1 0.6 GO:0032328 alanine transport(GO:0032328)
0.1 0.4 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.1 0.3 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 0.2 GO:0048633 cell-cell signaling involved in cell fate commitment(GO:0045168) negative regulation of auditory receptor cell differentiation(GO:0045608) positive regulation of skeletal muscle tissue growth(GO:0048633)
0.1 0.2 GO:0019417 sulfur oxidation(GO:0019417)
0.1 0.2 GO:0046462 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.1 0.6 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.1 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.0 0.2 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.2 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
0.0 0.4 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 2.3 GO:0030224 monocyte differentiation(GO:0030224) negative regulation of innate immune response(GO:0045824)
0.0 0.3 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.5 GO:0051451 myoblast migration(GO:0051451)
0.0 0.1 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.0 0.2 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.9 GO:0042269 regulation of natural killer cell mediated cytotoxicity(GO:0042269)
0.0 0.1 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0 0.1 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.3 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.8 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.0 0.1 GO:0040009 regulation of growth rate(GO:0040009)
0.0 0.5 GO:0032495 response to muramyl dipeptide(GO:0032495)
0.0 0.1 GO:0072560 glandular epithelial cell maturation(GO:0002071) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913) type B pancreatic cell maturation(GO:0072560)
0.0 0.6 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.2 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.0 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.1 GO:0051552 flavone metabolic process(GO:0051552)
0.0 0.6 GO:0006298 mismatch repair(GO:0006298)
0.0 0.3 GO:1904707 positive regulation of vascular smooth muscle cell proliferation(GO:1904707)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.2 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.9 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 1.3 GO:0016592 mediator complex(GO:0016592)
0.0 0.7 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.2 GO:0001940 male pronucleus(GO:0001940)
0.0 0.7 GO:0032982 myosin filament(GO:0032982)
0.0 0.3 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:0097196 Shu complex(GO:0097196)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.5 GO:0090545 Sin3 complex(GO:0016580) NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.2 GO:0030877 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) beta-catenin destruction complex(GO:0030877)
0.0 0.2 GO:0043194 axon initial segment(GO:0043194)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.1 2.0 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.3 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.1 0.6 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 0.3 GO:1904408 dihydronicotinamide riboside quinone reductase activity(GO:0001512) melatonin binding(GO:1904408)
0.1 0.6 GO:0004522 ribonuclease A activity(GO:0004522)
0.1 1.3 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.1 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.0 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.8 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.5 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.5 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.2 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 2.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 1.1 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.2 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 0.6 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 2.0 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.5 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.5 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 2.1 PID HNF3A PATHWAY FOXA1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.0 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.6 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.6 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.5 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.3 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 0.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.2 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 1.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins