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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for ZBTB18

Z-value: 0.66

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Transcription factors associated with ZBTB18

Gene Symbol Gene ID Gene Info
ZBTB18
ENSG00000179456.9 zinc finger and BTB domain containing 18

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZBTB18hg19_v2_chr1_+_244214577_244214593-0.563.8e-03Click!

Activity profile of ZBTB18 motif

Sorted Z-values of ZBTB18 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_152214098 3.31 ENST00000243347.3
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr5_+_118690466 2.52 ENST00000503646.1
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr17_+_77020325 1.75 ENST00000311661.4
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr17_+_77020224 1.75 ENST00000339142.2
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr15_+_67418047 1.47 ENST00000540846.2
SMAD3
SMAD family member 3
chr2_+_201994042 1.24 ENST00000417748.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr2_+_108994466 1.11 ENST00000272452.2
SULT1C4
sulfotransferase family, cytosolic, 1C, member 4
chr17_+_77020146 1.05 ENST00000579760.1
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr12_+_112563335 0.90 ENST00000549358.1
ENST00000257604.5
ENST00000548092.1
ENST00000552896.1
TRAFD1
TRAF-type zinc finger domain containing 1
chr12_+_112563303 0.89 ENST00000412615.2
TRAFD1
TRAF-type zinc finger domain containing 1
chrX_+_150151824 0.80 ENST00000455596.1
ENST00000448905.2
HMGB3
high mobility group box 3
chrX_-_154563889 0.74 ENST00000369449.2
ENST00000321926.4
CLIC2
chloride intracellular channel 2
chr2_-_145278475 0.72 ENST00000558170.2
ZEB2
zinc finger E-box binding homeobox 2
chr5_+_49962495 0.69 ENST00000515175.1
PARP8
poly (ADP-ribose) polymerase family, member 8
chr3_-_37216055 0.63 ENST00000336686.4
LRRFIP2
leucine rich repeat (in FLII) interacting protein 2
chr13_+_97874574 0.61 ENST00000343600.4
ENST00000345429.6
ENST00000376673.3
MBNL2
muscleblind-like splicing regulator 2
chr11_-_57089671 0.61 ENST00000532437.1
TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr17_+_32582293 0.59 ENST00000580907.1
ENST00000225831.4
CCL2
chemokine (C-C motif) ligand 2
chr2_-_152146385 0.57 ENST00000414946.1
ENST00000243346.5
NMI
N-myc (and STAT) interactor
chr9_+_100174344 0.55 ENST00000422139.2
TDRD7
tudor domain containing 7
chr9_+_118916082 0.55 ENST00000328252.3
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr9_+_100174232 0.53 ENST00000355295.4
TDRD7
tudor domain containing 7
chr12_+_26126681 0.53 ENST00000542865.1
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr2_-_89399845 0.52 ENST00000479981.1
IGKV1-16
immunoglobulin kappa variable 1-16
chrX_+_64808248 0.52 ENST00000609672.1
MSN
moesin
chr7_+_100770328 0.51 ENST00000223095.4
ENST00000445463.2
SERPINE1
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr2_-_230096756 0.50 ENST00000354069.6
PID1
phosphotyrosine interaction domain containing 1
chr6_+_155537771 0.49 ENST00000275246.7
TIAM2
T-cell lymphoma invasion and metastasis 2
chr16_+_24266874 0.48 ENST00000005284.3
CACNG3
calcium channel, voltage-dependent, gamma subunit 3
chr19_+_11649532 0.48 ENST00000252456.2
ENST00000592923.1
ENST00000535659.2
CNN1
calponin 1, basic, smooth muscle
chr11_+_71249071 0.47 ENST00000398534.3
KRTAP5-8
keratin associated protein 5-8
chr17_+_32612687 0.40 ENST00000305869.3
CCL11
chemokine (C-C motif) ligand 11
chr14_-_61748550 0.39 ENST00000555868.1
TMEM30B
transmembrane protein 30B
chr4_-_105416039 0.39 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr7_-_122339162 0.37 ENST00000340112.2
RNF133
ring finger protein 133
chr2_+_191045562 0.36 ENST00000340623.4
C2orf88
chromosome 2 open reading frame 88
chr3_-_44552094 0.36 ENST00000436261.1
ZNF852
zinc finger protein 852
chr5_-_151304337 0.36 ENST00000455880.2
ENST00000545569.1
ENST00000274576.4
GLRA1
glycine receptor, alpha 1
chr9_+_72658490 0.35 ENST00000377182.4
MAMDC2
MAM domain containing 2
chr15_-_55611306 0.34 ENST00000563262.1
RAB27A
RAB27A, member RAS oncogene family
chr10_+_97733786 0.33 ENST00000371198.2
CC2D2B
coiled-coil and C2 domain containing 2B
chrX_-_111923145 0.32 ENST00000371968.3
ENST00000536453.1
LHFPL1
lipoma HMGIC fusion partner-like 1
chr22_-_37823468 0.32 ENST00000402918.2
ELFN2
extracellular leucine-rich repeat and fibronectin type III domain containing 2
chr17_+_32597232 0.32 ENST00000378569.2
ENST00000200307.4
ENST00000394627.1
ENST00000394630.3
CCL7
chemokine (C-C motif) ligand 7
chr2_-_89597542 0.31 ENST00000465170.1
IGKV1-37
immunoglobulin kappa variable 1-37 (non-functional)
chr5_+_140792614 0.30 ENST00000398610.2
PCDHGA10
protocadherin gamma subfamily A, 10
chrX_+_48242863 0.30 ENST00000376886.2
ENST00000375517.3
SSX4
synovial sarcoma, X breakpoint 4
chr11_-_5537920 0.29 ENST00000380184.1
UBQLNL
ubiquilin-like
chr15_+_51669444 0.29 ENST00000396399.2
GLDN
gliomedin
chrX_-_19688475 0.28 ENST00000541422.1
SH3KBP1
SH3-domain kinase binding protein 1
chr20_+_57875658 0.28 ENST00000371025.3
EDN3
endothelin 3
chrX_-_110513703 0.27 ENST00000324068.1
CAPN6
calpain 6
chr11_+_94227129 0.27 ENST00000540349.1
ENST00000535502.1
ENST00000545130.1
ENST00000544253.1
ENST00000541144.1
ANKRD49
ankyrin repeat domain 49
chr2_+_89923550 0.27 ENST00000509129.1
IGKV1D-37
immunoglobulin kappa variable 1D-37 (non-functional)
chr7_-_71868354 0.27 ENST00000412588.1
CALN1
calneuron 1
chr2_-_7005785 0.26 ENST00000256722.5
ENST00000404168.1
ENST00000458098.1
CMPK2
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr11_+_5474638 0.26 ENST00000341449.2
OR51I2
olfactory receptor, family 51, subfamily I, member 2
chr1_-_2458026 0.25 ENST00000435556.3
ENST00000378466.3
PANK4
pantothenate kinase 4
chr6_-_163148700 0.25 ENST00000366894.1
ENST00000338468.3
PARK2
parkin RBR E3 ubiquitin protein ligase
chr2_-_74692473 0.25 ENST00000535045.1
ENST00000409065.1
ENST00000414701.1
ENST00000448666.1
ENST00000233616.4
ENST00000452063.2
MOGS
mannosyl-oligosaccharide glucosidase
chr16_-_30394143 0.25 ENST00000321367.3
ENST00000571393.1
SEPT1
septin 1
chr19_+_39903185 0.24 ENST00000409794.3
PLEKHG2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr9_+_116263778 0.23 ENST00000394646.3
RGS3
regulator of G-protein signaling 3
chr1_+_9005917 0.23 ENST00000549778.1
ENST00000480186.3
ENST00000377443.2
ENST00000377436.3
ENST00000377442.2
CA6
carbonic anhydrase VI
chrX_+_150151752 0.23 ENST00000325307.7
HMGB3
high mobility group box 3
chr4_+_15376165 0.23 ENST00000382383.3
ENST00000429690.1
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr14_+_67707826 0.23 ENST00000261681.4
MPP5
membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
chr9_+_116263639 0.23 ENST00000343817.5
RGS3
regulator of G-protein signaling 3
chrY_-_21239221 0.23 ENST00000447937.1
ENST00000331787.2
TTTY14
testis-specific transcript, Y-linked 14 (non-protein coding)
chr12_+_1738363 0.23 ENST00000397196.2
WNT5B
wingless-type MMTV integration site family, member 5B
chr11_-_34379546 0.22 ENST00000435224.2
ABTB2
ankyrin repeat and BTB (POZ) domain containing 2
chr10_+_105253661 0.22 ENST00000369780.4
NEURL
neuralized E3 ubiquitin protein ligase 1
chr16_+_28914680 0.22 ENST00000564112.1
ATP2A1
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr9_+_273038 0.22 ENST00000487230.1
ENST00000469391.1
DOCK8
dedicator of cytokinesis 8
chr8_+_104831472 0.22 ENST00000262231.10
ENST00000507740.1
RIMS2
regulating synaptic membrane exocytosis 2
chr1_+_26737253 0.21 ENST00000326279.6
LIN28A
lin-28 homolog A (C. elegans)
chr3_-_160167508 0.21 ENST00000479460.1
TRIM59
tripartite motif containing 59
chr16_-_31076332 0.20 ENST00000539836.3
ENST00000535577.1
ENST00000442862.2
ZNF668
zinc finger protein 668
chr11_+_128562372 0.20 ENST00000344954.6
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr1_+_42619070 0.20 ENST00000372581.1
GUCA2B
guanylate cyclase activator 2B (uroguanylin)
chrX_+_103031758 0.20 ENST00000303958.2
ENST00000361621.2
PLP1
proteolipid protein 1
chr5_-_149324306 0.19 ENST00000255266.5
PDE6A
phosphodiesterase 6A, cGMP-specific, rod, alpha
chr5_+_159895275 0.19 ENST00000517927.1
MIR146A
microRNA 146a
chr9_+_87283430 0.19 ENST00000376214.1
ENST00000376213.1
NTRK2
neurotrophic tyrosine kinase, receptor, type 2
chr11_+_59824127 0.19 ENST00000278865.3
MS4A3
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr17_-_15168624 0.19 ENST00000312280.3
ENST00000494511.1
ENST00000580584.1
PMP22
peripheral myelin protein 22
chr1_-_153518270 0.18 ENST00000354332.4
ENST00000368716.4
S100A4
S100 calcium binding protein A4
chr2_-_89417335 0.18 ENST00000490686.1
IGKV1-17
immunoglobulin kappa variable 1-17
chr11_+_65405556 0.18 ENST00000534313.1
ENST00000533361.1
ENST00000526137.1
SIPA1
signal-induced proliferation-associated 1
chr12_-_54785074 0.18 ENST00000338010.5
ENST00000550774.1
ZNF385A
zinc finger protein 385A
chrX_+_103031421 0.17 ENST00000433491.1
ENST00000418604.1
ENST00000443502.1
PLP1
proteolipid protein 1
chr7_-_37024665 0.17 ENST00000396040.2
ELMO1
engulfment and cell motility 1
chr6_+_163148973 0.17 ENST00000366888.2
PACRG
PARK2 co-regulated
chr15_+_31619013 0.16 ENST00000307145.3
KLF13
Kruppel-like factor 13
chr12_-_54785054 0.16 ENST00000352268.6
ENST00000549962.1
ZNF385A
zinc finger protein 385A
chr1_+_26737292 0.16 ENST00000254231.4
LIN28A
lin-28 homolog A (C. elegans)
chr1_-_217262969 0.16 ENST00000361525.3
ESRRG
estrogen-related receptor gamma
chr21_-_34185944 0.16 ENST00000479548.1
C21orf62
chromosome 21 open reading frame 62
chr19_+_42806250 0.15 ENST00000598490.1
ENST00000341747.3
PRR19
proline rich 19
chr5_+_132009675 0.15 ENST00000231449.2
ENST00000350025.2
IL4
interleukin 4
chr11_+_32112431 0.14 ENST00000054950.3
RCN1
reticulocalbin 1, EF-hand calcium binding domain
chr11_+_59824060 0.14 ENST00000395032.2
ENST00000358152.2
MS4A3
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr11_+_15136462 0.14 ENST00000379556.3
ENST00000424273.1
INSC
inscuteable homolog (Drosophila)
chr16_+_6069586 0.14 ENST00000547372.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr5_+_140782351 0.14 ENST00000573521.1
PCDHGA9
protocadherin gamma subfamily A, 9
chrX_-_30877837 0.13 ENST00000378930.3
TAB3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr11_-_40315640 0.13 ENST00000278198.2
LRRC4C
leucine rich repeat containing 4C
chr4_+_156824840 0.13 ENST00000536354.2
TDO2
tryptophan 2,3-dioxygenase
chr7_+_62809239 0.13 ENST00000456890.1
AC006455.1
AC006455.1
chr4_+_75311019 0.13 ENST00000502307.1
AREG
amphiregulin
chr2_-_163099885 0.12 ENST00000443424.1
FAP
fibroblast activation protein, alpha
chr19_+_9251052 0.12 ENST00000247956.6
ENST00000360385.3
ZNF317
zinc finger protein 317
chrX_-_48056199 0.12 ENST00000311798.1
ENST00000347757.1
SSX5
synovial sarcoma, X breakpoint 5
chrX_-_77225135 0.12 ENST00000458128.1
PGAM4
phosphoglycerate mutase family member 4
chr12_+_2162447 0.12 ENST00000335762.5
ENST00000399655.1
CACNA1C
calcium channel, voltage-dependent, L type, alpha 1C subunit
chr11_-_62323702 0.12 ENST00000530285.1
AHNAK
AHNAK nucleoprotein
chr2_-_163100045 0.11 ENST00000188790.4
FAP
fibroblast activation protein, alpha
chr2_+_90139056 0.11 ENST00000492446.1
IGKV1D-16
immunoglobulin kappa variable 1D-16
chr17_-_19651654 0.11 ENST00000395555.3
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chrX_+_153770421 0.10 ENST00000369609.5
ENST00000369607.1
IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr20_+_57875758 0.10 ENST00000395654.3
EDN3
endothelin 3
chr2_+_219247021 0.10 ENST00000539932.1
SLC11A1
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
chr17_-_19651668 0.10 ENST00000494157.2
ENST00000225740.6
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr1_-_217262933 0.10 ENST00000359162.2
ESRRG
estrogen-related receptor gamma
chr17_+_19912640 0.10 ENST00000395527.4
ENST00000583482.2
ENST00000583528.1
ENST00000583463.1
SPECC1
sperm antigen with calponin homology and coiled-coil domains 1
chr15_-_43559055 0.10 ENST00000220420.5
ENST00000349114.4
TGM5
transglutaminase 5
chr4_-_111563076 0.10 ENST00000354925.2
ENST00000511990.1
PITX2
paired-like homeodomain 2
chr8_-_49834299 0.09 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr20_+_30467600 0.09 ENST00000375934.4
ENST00000375922.4
TTLL9
tubulin tyrosine ligase-like family, member 9
chr6_-_39197226 0.09 ENST00000359534.3
KCNK5
potassium channel, subfamily K, member 5
chr21_-_35883541 0.08 ENST00000399284.1
KCNE1
potassium voltage-gated channel, Isk-related family, member 1
chr2_+_113885138 0.08 ENST00000409930.3
IL1RN
interleukin 1 receptor antagonist
chr6_-_163148780 0.08 ENST00000366892.1
ENST00000366898.1
ENST00000366897.1
ENST00000366896.1
PARK2
parkin RBR E3 ubiquitin protein ligase
chr17_+_48638371 0.08 ENST00000360761.4
ENST00000352832.5
ENST00000354983.4
CACNA1G
calcium channel, voltage-dependent, T type, alpha 1G subunit
chr8_-_49833978 0.08 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr17_-_62050278 0.07 ENST00000578147.1
ENST00000435607.1
SCN4A
sodium channel, voltage-gated, type IV, alpha subunit
chr19_+_50936142 0.07 ENST00000357701.5
MYBPC2
myosin binding protein C, fast type
chr11_-_128894053 0.06 ENST00000392657.3
ARHGAP32
Rho GTPase activating protein 32
chr19_-_52148798 0.06 ENST00000534261.2
SIGLEC5
sialic acid binding Ig-like lectin 5
chr9_+_97488939 0.06 ENST00000277198.2
ENST00000297979.5
C9orf3
chromosome 9 open reading frame 3
chr6_+_160542821 0.06 ENST00000366963.4
SLC22A1
solute carrier family 22 (organic cation transporter), member 1
chr1_+_32608566 0.06 ENST00000545542.1
KPNA6
karyopherin alpha 6 (importin alpha 7)
chr3_+_121311966 0.06 ENST00000338040.4
FBXO40
F-box protein 40
chr1_-_156647189 0.06 ENST00000368223.3
NES
nestin
chr12_-_56122124 0.06 ENST00000552754.1
CD63
CD63 molecule
chr2_-_225434538 0.06 ENST00000409096.1
CUL3
cullin 3
chr11_+_76494253 0.05 ENST00000333090.4
TSKU
tsukushi, small leucine rich proteoglycan
chr3_-_52273098 0.05 ENST00000499914.2
ENST00000305533.5
ENST00000597542.1
TWF2
TLR9
twinfilin actin-binding protein 2
toll-like receptor 9
chr15_+_49715293 0.05 ENST00000267843.4
ENST00000560270.1
FGF7
fibroblast growth factor 7
chr4_+_47487285 0.05 ENST00000273859.3
ENST00000504445.1
ATP10D
ATPase, class V, type 10D
chr10_-_71332994 0.05 ENST00000242462.4
NEUROG3
neurogenin 3
chr15_-_31453157 0.05 ENST00000559177.1
ENST00000558445.1
TRPM1
transient receptor potential cation channel, subfamily M, member 1
chr13_+_113777105 0.04 ENST00000409306.1
ENST00000375551.3
ENST00000375559.3
F10
coagulation factor X
chr4_+_88571429 0.04 ENST00000339673.6
ENST00000282479.7
DMP1
dentin matrix acidic phosphoprotein 1
chr7_+_95115210 0.04 ENST00000428113.1
ENST00000325885.5
ASB4
ankyrin repeat and SOCS box containing 4
chr10_+_98064085 0.04 ENST00000419175.1
ENST00000371174.2
DNTT
DNA nucleotidylexotransferase
chr1_-_99470558 0.04 ENST00000370188.3
LPPR5
Lipid phosphate phosphatase-related protein type 5
chr19_+_48673949 0.04 ENST00000328759.7
C19orf68
chromosome 19 open reading frame 68
chr7_-_154863264 0.04 ENST00000395731.2
ENST00000543018.1
HTR5A-AS1
HTR5A antisense RNA 1
chr17_-_41174424 0.04 ENST00000355653.3
VAT1
vesicle amine transport 1
chr12_-_56122426 0.04 ENST00000551173.1
CD63
CD63 molecule
chr11_+_63870660 0.03 ENST00000246841.3
FLRT1
fibronectin leucine rich transmembrane protein 1
chr7_-_156803329 0.03 ENST00000252971.6
MNX1
motor neuron and pancreas homeobox 1
chr12_-_56121580 0.03 ENST00000550776.1
CD63
CD63 molecule
chr12_-_48119340 0.03 ENST00000229003.3
ENDOU
endonuclease, polyU-specific
chr12_-_56122220 0.03 ENST00000552692.1
CD63
CD63 molecule
chr3_-_160167301 0.03 ENST00000494486.1
TRIM59
tripartite motif containing 59
chr1_+_38022572 0.02 ENST00000541606.1
DNALI1
dynein, axonemal, light intermediate chain 1
chr1_-_11907829 0.02 ENST00000376480.3
NPPA
natriuretic peptide A
chr20_+_56725952 0.02 ENST00000371168.3
C20orf85
chromosome 20 open reading frame 85
chr6_-_74363803 0.02 ENST00000355773.5
SLC17A5
solute carrier family 17 (acidic sugar transporter), member 5
chr1_-_99470368 0.02 ENST00000263177.4
LPPR5
Lipid phosphate phosphatase-related protein type 5
chr10_-_123357598 0.02 ENST00000358487.5
ENST00000369058.3
ENST00000369060.4
ENST00000359354.2
FGFR2
fibroblast growth factor receptor 2
chr12_-_48119301 0.01 ENST00000545824.2
ENST00000422538.3
ENDOU
endonuclease, polyU-specific
chr6_+_160542870 0.01 ENST00000324965.4
ENST00000457470.2
SLC22A1
solute carrier family 22 (organic cation transporter), member 1
chr1_+_53527854 0.01 ENST00000371500.3
ENST00000395871.2
ENST00000312553.5
PODN
podocan
chr17_+_42385927 0.01 ENST00000426726.3
ENST00000590941.1
ENST00000225441.7
RUNDC3A
RUN domain containing 3A
chr19_-_15918936 0.01 ENST00000334920.2
OR10H1
olfactory receptor, family 10, subfamily H, member 1
chr15_+_92937144 0.00 ENST00000539113.1
ENST00000555434.1
ST8SIA2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB18

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.5 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.3 1.5 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.2 0.6 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.2 0.5 GO:0001300 chronological cell aging(GO:0001300) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 0.5 GO:0090298 negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859) negative regulation of ATP biosynthetic process(GO:2001170)
0.1 1.2 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 0.7 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.6 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.1 0.5 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 3.3 GO:0030728 ovulation(GO:0030728)
0.1 0.3 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.1 0.4 GO:0035962 response to interleukin-13(GO:0035962)
0.1 0.5 GO:0022614 membrane to membrane docking(GO:0022614)
0.1 0.2 GO:0031446 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.1 0.3 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.1 0.4 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 0.4 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.1 0.4 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 0.2 GO:0097325 melanocyte proliferation(GO:0097325)
0.1 0.3 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 0.2 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563) negative regulation of response to alcohol(GO:1901420)
0.1 0.2 GO:0071288 cellular response to mercury ion(GO:0071288)
0.0 0.4 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.7 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.0 0.3 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 0.2 GO:0042631 cellular response to water deprivation(GO:0042631)
0.0 0.1 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.0 1.1 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.2 GO:0099538 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.0 1.3 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 0.1 GO:0055073 cadmium ion homeostasis(GO:0055073) divalent metal ion export(GO:0070839)
0.0 0.1 GO:0060127 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 1.8 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 0.1 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.0 0.5 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0 0.4 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.4 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.2 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.5 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 0.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.2 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.5 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.6 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.1 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.0 0.2 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 2.3 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.0 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.0 0.1 GO:0045349 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.0 0.1 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.1 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0 0.1 GO:0048241 epinephrine transport(GO:0048241)
0.0 0.5 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 1.2 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.1 1.1 GO:0033391 chromatoid body(GO:0033391)
0.0 4.9 GO:0005581 collagen trimer(GO:0005581)
0.0 3.3 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.6 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.8 GO:0071437 invadopodium(GO:0071437)
0.0 0.2 GO:0043219 myelin sheath adaxonal region(GO:0035749) lateral loop(GO:0043219)
0.0 0.4 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.1 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.5 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.6 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 3.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.4 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.1 0.4 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 0.4 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.6 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.3 GO:0009041 uridylate kinase activity(GO:0009041)
0.1 0.2 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.1 0.3 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 2.3 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.3 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 1.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 4.6 GO:0005518 collagen binding(GO:0005518)
0.0 0.2 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.2 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.0 1.2 GO:0097200 death receptor binding(GO:0005123) cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.3 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 1.0 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.1 GO:0051139 metal ion:proton antiporter activity(GO:0051139)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.5 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.1 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.2 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.1 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.0 0.4 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.6 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.7 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.1 GO:0008513 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.1 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.3 GO:0015926 glucosidase activity(GO:0015926)
0.0 0.7 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.3 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.2 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.3 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0031208 POZ domain binding(GO:0031208)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.3 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 4.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.1 PID AURORA A PATHWAY Aurora A signaling
0.0 0.6 PID IL23 PATHWAY IL23-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 1.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 1.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.3 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation