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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for ZBTB33_CHD2

Z-value: 1.39

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Transcription factors associated with ZBTB33_CHD2

Gene Symbol Gene ID Gene Info
ZBTB33
ENSG00000177485.6 zinc finger and BTB domain containing 33
CHD2
ENSG00000173575.14 chromodomain helicase DNA binding protein 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CHD2hg19_v2_chr15_+_93443419_93443580-0.242.6e-01Click!
ZBTB33hg19_v2_chrX_+_119384607_1193847200.116.0e-01Click!

Activity profile of ZBTB33_CHD2 motif

Sorted Z-values of ZBTB33_CHD2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_7761301 5.59 ENST00000332439.4
ENST00000570446.1
CYB5D1
cytochrome b5 domain containing 1
chr12_+_27396901 3.83 ENST00000541191.1
ENST00000389032.3
STK38L
serine/threonine kinase 38 like
chr3_+_8543393 3.30 ENST00000157600.3
ENST00000415597.1
ENST00000535732.1
LMCD1
LIM and cysteine-rich domains 1
chr3_+_8543561 3.29 ENST00000397386.3
LMCD1
LIM and cysteine-rich domains 1
chr13_+_115047097 3.29 ENST00000351487.5
UPF3A
UPF3 regulator of nonsense transcripts homolog A (yeast)
chr13_+_115047053 3.10 ENST00000375299.3
UPF3A
UPF3 regulator of nonsense transcripts homolog A (yeast)
chr13_+_42846272 2.92 ENST00000025301.2
AKAP11
A kinase (PRKA) anchor protein 11
chr5_+_176449726 2.74 ENST00000261948.4
ENST00000511834.1
ENST00000503039.1
ZNF346
zinc finger protein 346
chr5_+_176449684 2.46 ENST00000506693.1
ENST00000358149.3
ENST00000512315.1
ENST00000503425.1
ZNF346
zinc finger protein 346
chr6_-_146285455 2.43 ENST00000367505.2
SHPRH
SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase
chr3_+_8543533 2.29 ENST00000454244.1
LMCD1
LIM and cysteine-rich domains 1
chr6_-_146285221 2.29 ENST00000367503.3
ENST00000438092.2
ENST00000275233.7
SHPRH
SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase
chr1_+_104068562 2.20 ENST00000423855.2
RNPC3
RNA-binding region (RNP1, RRM) containing 3
chr12_-_27091183 2.14 ENST00000544548.1
ENST00000261191.7
ENST00000537336.1
ASUN
asunder spermatogenesis regulator
chr1_-_92371839 2.05 ENST00000370399.2
TGFBR3
transforming growth factor, beta receptor III
chr12_-_27090896 2.02 ENST00000539625.1
ENST00000538727.1
ASUN
asunder spermatogenesis regulator
chr8_+_37963311 1.90 ENST00000428278.2
ENST00000521652.1
ASH2L
ash2 (absent, small, or homeotic)-like (Drosophila)
chr3_-_18466026 1.89 ENST00000417717.2
SATB1
SATB homeobox 1
chr8_+_37963011 1.88 ENST00000250635.7
ENST00000517719.1
ENST00000545394.1
ASH2L
ash2 (absent, small, or homeotic)-like (Drosophila)
chr1_-_78148324 1.85 ENST00000370801.3
ENST00000433749.1
ZZZ3
zinc finger, ZZ-type containing 3
chr13_-_21750659 1.84 ENST00000400018.3
ENST00000314759.5
SKA3
spindle and kinetochore associated complex subunit 3
chr1_+_104068312 1.82 ENST00000524631.1
ENST00000531883.1
ENST00000533099.1
ENST00000527062.1
RNPC3
RNA-binding region (RNP1, RRM) containing 3
chr10_-_127408011 1.73 ENST00000531977.1
ENST00000527483.1
ENST00000525909.1
ENST00000528844.1
ENST00000423178.2
RP11-383C5.4
RP11-383C5.4
chr9_-_125667618 1.71 ENST00000423239.2
RC3H2
ring finger and CCCH-type domains 2
chr17_-_7761172 1.68 ENST00000333775.5
ENST00000575771.1
LSMD1
LSM domain containing 1
chr12_-_80328700 1.67 ENST00000550107.1
PPP1R12A
protein phosphatase 1, regulatory subunit 12A
chr17_-_53046058 1.64 ENST00000571584.1
ENST00000299335.3
COX11
cytochrome c oxidase assembly homolog 11 (yeast)
chr19_-_37263693 1.64 ENST00000591344.1
ZNF850
zinc finger protein 850
chr2_-_677369 1.64 ENST00000281017.3
TMEM18
transmembrane protein 18
chr3_-_160117301 1.60 ENST00000326448.7
ENST00000498409.1
ENST00000475677.1
ENST00000478536.1
IFT80
intraflagellar transport 80 homolog (Chlamydomonas)
chr15_-_56035177 1.59 ENST00000389286.4
ENST00000561292.1
PRTG
protogenin
chr12_+_27091426 1.58 ENST00000546072.1
ENST00000327214.5
FGFR1OP2
FGFR1 oncogene partner 2
chr12_+_27091316 1.52 ENST00000229395.3
FGFR1OP2
FGFR1 oncogene partner 2
chr7_-_129845313 1.52 ENST00000397622.2
TMEM209
transmembrane protein 209
chr2_+_170683979 1.51 ENST00000418381.1
UBR3
ubiquitin protein ligase E3 component n-recognin 3 (putative)
chr18_+_59854480 1.43 ENST00000256858.6
ENST00000398130.2
KIAA1468
KIAA1468
chr20_+_17949544 1.39 ENST00000377710.5
MGME1
mitochondrial genome maintenance exonuclease 1
chr5_-_89705537 1.38 ENST00000522864.1
ENST00000522083.1
ENST00000522565.1
ENST00000522842.1
ENST00000283122.3
CETN3
centrin, EF-hand protein, 3
chr17_+_4843679 1.37 ENST00000576229.1
RNF167
ring finger protein 167
chr11_-_118436606 1.37 ENST00000530872.1
IFT46
intraflagellar transport 46 homolog (Chlamydomonas)
chr2_+_170683942 1.37 ENST00000272793.5
UBR3
ubiquitin protein ligase E3 component n-recognin 3 (putative)
chr11_-_118436707 1.34 ENST00000264020.2
ENST00000264021.3
IFT46
intraflagellar transport 46 homolog (Chlamydomonas)
chr20_+_17949684 1.34 ENST00000377709.1
MGME1
mitochondrial genome maintenance exonuclease 1
chr6_-_116575226 1.33 ENST00000420283.1
TSPYL4
TSPY-like 4
chr3_+_42642106 1.32 ENST00000232978.8
NKTR
natural killer-tumor recognition sequence
chr16_+_14165160 1.29 ENST00000574998.1
ENST00000571589.1
ENST00000574045.1
MKL2
MKL/myocardin-like 2
chr6_+_35995531 1.28 ENST00000229794.4
MAPK14
mitogen-activated protein kinase 14
chr20_+_17949724 1.27 ENST00000377704.4
MGME1
mitochondrial genome maintenance exonuclease 1
chr6_+_35995488 1.27 ENST00000229795.3
MAPK14
mitogen-activated protein kinase 14
chr2_-_55844720 1.24 ENST00000345102.5
ENST00000272313.5
ENST00000407823.3
SMEK2
SMEK homolog 2, suppressor of mek1 (Dictyostelium)
chr18_-_59854203 1.23 ENST00000589339.1
ENST00000357637.5
ENST00000585458.1
ENST00000400334.3
ENST00000587134.1
ENST00000585923.1
ENST00000590765.1
ENST00000589720.1
ENST00000588571.1
ENST00000585344.1
PIGN
phosphatidylinositol glycan anchor biosynthesis, class N
chr9_-_125667494 1.21 ENST00000335387.5
ENST00000357244.2
ENST00000373665.2
RC3H2
ring finger and CCCH-type domains 2
chr3_-_165555200 1.19 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
BCHE
butyrylcholinesterase
chr5_-_10249990 1.19 ENST00000511437.1
ENST00000280330.8
ENST00000510047.1
FAM173B
family with sequence similarity 173, member B
chr11_-_94227029 1.18 ENST00000323977.3
ENST00000536754.1
ENST00000323929.3
MRE11A
MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
chr4_+_17812525 1.17 ENST00000251496.2
NCAPG
non-SMC condensin I complex, subunit G
chr3_+_160117418 1.17 ENST00000465903.1
ENST00000485645.1
ENST00000360111.2
ENST00000472991.1
ENST00000467468.1
ENST00000469762.1
ENST00000489573.1
ENST00000462787.1
ENST00000490207.1
ENST00000485867.1
SMC4
structural maintenance of chromosomes 4
chr22_-_21356375 1.17 ENST00000215742.4
ENST00000399133.2
THAP7
THAP domain containing 7
chr15_+_78730531 1.16 ENST00000258886.8
IREB2
iron-responsive element binding protein 2
chr4_-_17812309 1.16 ENST00000382247.1
ENST00000536863.1
DCAF16
DDB1 and CUL4 associated factor 16
chr6_+_71122974 1.16 ENST00000418814.2
FAM135A
family with sequence similarity 135, member A
chr10_-_64576105 1.14 ENST00000242480.3
ENST00000411732.1
EGR2
early growth response 2
chr1_+_231473743 1.14 ENST00000295050.7
SPRTN
SprT-like N-terminal domain
chr12_-_80328949 1.14 ENST00000450142.2
PPP1R12A
protein phosphatase 1, regulatory subunit 12A
chr3_-_93781750 1.11 ENST00000314636.2
DHFRL1
dihydrofolate reductase-like 1
chr1_+_26146397 1.09 ENST00000374303.2
ENST00000533762.1
ENST00000529116.1
ENST00000474295.1
ENST00000488327.2
ENST00000472643.1
ENST00000526894.1
ENST00000524618.1
ENST00000374307.5
MTFR1L
mitochondrial fission regulator 1-like
chr3_+_32280159 1.09 ENST00000458535.2
ENST00000307526.3
CMTM8
CKLF-like MARVEL transmembrane domain containing 8
chr12_+_123237321 1.08 ENST00000280557.6
ENST00000455982.2
DENR
density-regulated protein
chr13_-_22178284 1.06 ENST00000468222.2
ENST00000382374.4
MICU2
mitochondrial calcium uptake 2
chr1_+_174969262 1.06 ENST00000406752.1
ENST00000405362.1
CACYBP
calcyclin binding protein
chr5_-_73937244 1.04 ENST00000302351.4
ENST00000510316.1
ENST00000508331.1
ENC1
ectodermal-neural cortex 1 (with BTB domain)
chr1_+_26146674 1.03 ENST00000525713.1
ENST00000374301.3
MTFR1L
mitochondrial fission regulator 1-like
chr9_+_26956371 1.03 ENST00000380062.5
ENST00000518614.1
IFT74
intraflagellar transport 74 homolog (Chlamydomonas)
chr3_+_160117087 1.03 ENST00000357388.3
SMC4
structural maintenance of chromosomes 4
chr5_-_72861484 1.01 ENST00000296785.3
ANKRA2
ankyrin repeat, family A (RFXANK-like), 2
chr12_+_123319973 1.01 ENST00000253083.4
HIP1R
huntingtin interacting protein 1 related
chr17_+_4843654 0.99 ENST00000575111.1
RNF167
ring finger protein 167
chr17_+_4843303 0.99 ENST00000571816.1
RNF167
ring finger protein 167
chr11_+_93474786 0.98 ENST00000331239.4
ENST00000533585.1
ENST00000528099.1
ENST00000354421.3
ENST00000540113.1
ENST00000530620.1
ENST00000527003.1
ENST00000531650.1
ENST00000530279.1
C11orf54
chromosome 11 open reading frame 54
chr19_+_42364313 0.98 ENST00000601492.1
ENST00000600467.1
ENST00000221975.2
RPS19
ribosomal protein S19
chr4_+_25378912 0.96 ENST00000510092.1
ENST00000505991.1
ANAPC4
anaphase promoting complex subunit 4
chr17_-_61920280 0.95 ENST00000448276.2
ENST00000577990.1
SMARCD2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
chr17_-_7761256 0.94 ENST00000575208.1
LSMD1
LSM domain containing 1
chr13_-_41768654 0.93 ENST00000379483.3
KBTBD7
kelch repeat and BTB (POZ) domain containing 7
chr12_-_29534074 0.92 ENST00000546839.1
ENST00000360150.4
ENST00000552155.1
ENST00000550353.1
ENST00000548441.1
ENST00000552132.1
ERGIC2
ERGIC and golgi 2
chr7_+_2443202 0.91 ENST00000258711.6
CHST12
carbohydrate (chondroitin 4) sulfotransferase 12
chr2_-_43823093 0.91 ENST00000405006.4
THADA
thyroid adenoma associated
chr6_+_25279651 0.91 ENST00000329474.6
LRRC16A
leucine rich repeat containing 16A
chr17_+_34900737 0.90 ENST00000304718.4
ENST00000485685.2
GGNBP2
gametogenetin binding protein 2
chr15_+_44580899 0.89 ENST00000559222.1
ENST00000299957.6
CASC4
cancer susceptibility candidate 4
chr21_-_34144157 0.89 ENST00000331923.4
PAXBP1
PAX3 and PAX7 binding protein 1
chr4_-_178363581 0.88 ENST00000264595.2
AGA
aspartylglucosaminidase
chr6_+_71123107 0.87 ENST00000370479.3
ENST00000505769.1
ENST00000515323.1
ENST00000515280.1
ENST00000507085.1
ENST00000457062.2
ENST00000361499.3
FAM135A
family with sequence similarity 135, member A
chr17_+_4843413 0.87 ENST00000572430.1
ENST00000262482.6
RNF167
ring finger protein 167
chr6_+_2765595 0.87 ENST00000380773.4
ENST00000380771.4
WRNIP1
Werner helicase interacting protein 1
chr4_+_25378826 0.87 ENST00000315368.3
ANAPC4
anaphase promoting complex subunit 4
chr14_+_24867992 0.86 ENST00000382554.3
NYNRIN
NYN domain and retroviral integrase containing
chr10_-_126847276 0.86 ENST00000531469.1
CTBP2
C-terminal binding protein 2
chr1_+_28052456 0.86 ENST00000373954.6
ENST00000419687.2
FAM76A
family with sequence similarity 76, member A
chr9_+_139971921 0.85 ENST00000409858.3
UAP1L1
UDP-N-acteylglucosamine pyrophosphorylase 1-like 1
chr19_+_42364460 0.85 ENST00000593863.1
RPS19
ribosomal protein S19
chr10_+_54074033 0.83 ENST00000373970.3
DKK1
dickkopf WNT signaling pathway inhibitor 1
chr6_+_35995552 0.81 ENST00000468133.1
MAPK14
mitogen-activated protein kinase 14
chr10_-_77161650 0.80 ENST00000372524.4
ZNF503
zinc finger protein 503
chr18_+_77623668 0.80 ENST00000316249.3
KCNG2
potassium voltage-gated channel, subfamily G, member 2
chr15_+_44580955 0.80 ENST00000345795.2
ENST00000360824.3
CASC4
cancer susceptibility candidate 4
chr2_-_201753980 0.78 ENST00000443398.1
ENST00000286175.8
ENST00000409449.1
PPIL3
peptidylprolyl isomerase (cyclophilin)-like 3
chr1_+_100316041 0.78 ENST00000370165.3
ENST00000370163.3
ENST00000294724.4
AGL
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chr7_-_75677251 0.78 ENST00000431581.1
ENST00000359697.3
ENST00000451157.1
ENST00000340062.5
ENST00000360591.3
ENST00000248600.1
STYXL1
serine/threonine/tyrosine interacting-like 1
chr10_+_127408263 0.77 ENST00000337623.3
C10orf137
erythroid differentiation regulatory factor 1
chr2_-_222436988 0.76 ENST00000409854.1
ENST00000281821.2
ENST00000392071.4
ENST00000443796.1
EPHA4
EPH receptor A4
chr1_+_100315613 0.76 ENST00000361915.3
AGL
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chr1_-_174992544 0.76 ENST00000476371.1
MRPS14
mitochondrial ribosomal protein S14
chr7_-_35734730 0.76 ENST00000396081.1
ENST00000311350.3
HERPUD2
HERPUD family member 2
chr4_+_71768043 0.75 ENST00000502869.1
ENST00000309395.2
ENST00000396051.2
MOB1B
MOB kinase activator 1B
chr19_+_42363917 0.74 ENST00000598742.1
RPS19
ribosomal protein S19
chr4_+_144434584 0.74 ENST00000283131.3
SMARCA5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr13_-_79979952 0.73 ENST00000438724.1
RBM26
RNA binding motif protein 26
chr2_+_203499901 0.72 ENST00000303116.6
ENST00000392238.2
FAM117B
family with sequence similarity 117, member B
chr2_+_214149113 0.71 ENST00000331683.5
ENST00000432529.2
ENST00000413312.1
ENST00000272898.7
ENST00000447990.1
SPAG16
sperm associated antigen 16
chr15_-_73925651 0.71 ENST00000545878.1
ENST00000287226.8
ENST00000345330.4
NPTN
neuroplastin
chr3_-_101232019 0.71 ENST00000394095.2
ENST00000394091.1
ENST00000394094.2
ENST00000358203.3
ENST00000348610.3
ENST00000314261.7
SENP7
SUMO1/sentrin specific peptidase 7
chr3_+_108308513 0.70 ENST00000361582.3
DZIP3
DAZ interacting zinc finger protein 3
chr4_+_120133791 0.70 ENST00000274030.6
USP53
ubiquitin specific peptidase 53
chr11_-_71791726 0.70 ENST00000393695.3
NUMA1
nuclear mitotic apparatus protein 1
chr12_-_133263893 0.70 ENST00000535270.1
ENST00000320574.5
POLE
polymerase (DNA directed), epsilon, catalytic subunit
chr2_+_120517174 0.70 ENST00000263708.2
PTPN4
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr6_+_3849584 0.70 ENST00000380274.1
ENST00000380272.3
FAM50B
family with sequence similarity 50, member B
chr2_-_39664405 0.69 ENST00000341681.5
ENST00000263881.3
MAP4K3
mitogen-activated protein kinase kinase kinase kinase 3
chr13_+_100741269 0.69 ENST00000376286.4
ENST00000376279.3
ENST00000376285.1
PCCA
propionyl CoA carboxylase, alpha polypeptide
chrX_-_13752675 0.69 ENST00000380579.1
ENST00000458511.2
ENST00000519885.1
ENST00000358231.5
ENST00000518847.1
ENST00000453655.2
ENST00000359680.5
TRAPPC2
trafficking protein particle complex 2
chr15_-_34880646 0.68 ENST00000543376.1
GOLGA8A
golgin A8 family, member A
chr11_+_47291645 0.68 ENST00000395336.3
ENST00000402192.2
MADD
MAP-kinase activating death domain
chr8_+_143808605 0.67 ENST00000336138.3
THEM6
thioesterase superfamily member 6
chr1_-_45672221 0.67 ENST00000359600.5
ZSWIM5
zinc finger, SWIM-type containing 5
chr9_-_123605177 0.66 ENST00000373904.5
ENST00000210313.3
PSMD5
proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
chr19_+_46002868 0.66 ENST00000396735.2
PPM1N
protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)
chr5_+_36152163 0.65 ENST00000274255.6
SKP2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr13_-_79979919 0.65 ENST00000267229.7
RBM26
RNA binding motif protein 26
chr16_-_80926457 0.65 ENST00000563626.1
ENST00000562231.1
RP11-314O13.1
RP11-314O13.1
chr20_+_49126881 0.65 ENST00000371621.3
ENST00000541713.1
PTPN1
protein tyrosine phosphatase, non-receptor type 1
chr15_-_48470544 0.65 ENST00000267836.6
MYEF2
myelin expression factor 2
chr14_+_61788429 0.65 ENST00000332981.5
PRKCH
protein kinase C, eta
chr15_-_48470558 0.65 ENST00000324324.7
MYEF2
myelin expression factor 2
chr11_-_71791435 0.64 ENST00000351960.6
ENST00000541719.1
ENST00000535111.1
NUMA1
nuclear mitotic apparatus protein 1
chr4_+_128886532 0.64 ENST00000444616.1
ENST00000388795.5
C4orf29
chromosome 4 open reading frame 29
chr20_-_17949100 0.64 ENST00000431277.1
SNX5
sorting nexin 5
chr12_+_102513950 0.64 ENST00000378128.3
ENST00000327680.2
ENST00000541394.1
ENST00000543784.1
PARPBP
PARP1 binding protein
chr11_-_71791518 0.64 ENST00000537217.1
ENST00000366394.3
ENST00000358965.6
ENST00000546131.1
ENST00000543937.1
ENST00000368959.5
ENST00000541641.1
NUMA1
nuclear mitotic apparatus protein 1
chr5_-_73936451 0.64 ENST00000537006.1
ENC1
ectodermal-neural cortex 1 (with BTB domain)
chr2_-_20101701 0.63 ENST00000402414.1
ENST00000333610.3
TTC32
tetratricopeptide repeat domain 32
chr12_+_56661033 0.63 ENST00000433805.2
COQ10A
coenzyme Q10 homolog A (S. cerevisiae)
chr2_-_157189180 0.63 ENST00000539077.1
ENST00000424077.1
ENST00000426264.1
ENST00000339562.4
ENST00000421709.1
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr6_-_16761678 0.62 ENST00000244769.4
ENST00000436367.1
ATXN1
ataxin 1
chr4_+_128886424 0.62 ENST00000398965.1
C4orf29
chromosome 4 open reading frame 29
chr1_-_70820357 0.62 ENST00000370944.4
ENST00000262346.6
ANKRD13C
ankyrin repeat domain 13C
chr11_+_93474757 0.62 ENST00000528288.1
C11orf54
chromosome 11 open reading frame 54
chr4_-_68411275 0.62 ENST00000273853.6
CENPC
centromere protein C
chr5_+_36152091 0.61 ENST00000274254.5
SKP2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr10_-_7829909 0.61 ENST00000379562.4
ENST00000543003.1
ENST00000535925.1
KIN
KIN, antigenic determinant of recA protein homolog (mouse)
chr8_-_145980968 0.60 ENST00000292562.7
ZNF251
zinc finger protein 251
chr1_-_6295975 0.60 ENST00000343813.5
ENST00000362035.3
ICMT
isoprenylcysteine carboxyl methyltransferase
chr7_-_150038704 0.60 ENST00000466675.1
ENST00000482669.1
ENST00000467793.1
ENST00000223271.3
RARRES2
retinoic acid receptor responder (tazarotene induced) 2
chr5_+_138629337 0.60 ENST00000394805.3
ENST00000512876.1
ENST00000513678.1
MATR3
matrin 3
chr8_+_95835438 0.60 ENST00000521860.1
ENST00000519457.1
ENST00000519053.1
ENST00000523731.1
ENST00000447247.1
INTS8
integrator complex subunit 8
chr1_+_24742264 0.60 ENST00000374399.4
ENST00000003912.3
ENST00000358028.4
ENST00000339255.2
NIPAL3
NIPA-like domain containing 3
chr3_-_137893721 0.59 ENST00000505015.2
ENST00000260803.4
DBR1
debranching RNA lariats 1
chr4_-_110624564 0.58 ENST00000352981.3
ENST00000265164.2
ENST00000505486.1
CASP6
caspase 6, apoptosis-related cysteine peptidase
chr4_-_90758227 0.58 ENST00000506691.1
ENST00000394986.1
ENST00000506244.1
ENST00000394989.2
ENST00000394991.3
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr17_-_7760779 0.58 ENST00000335155.5
ENST00000575071.1
LSMD1
LSM domain containing 1
chr2_+_189156389 0.57 ENST00000409843.1
GULP1
GULP, engulfment adaptor PTB domain containing 1
chr17_+_55162453 0.57 ENST00000575322.1
ENST00000337714.3
ENST00000314126.3
AKAP1
A kinase (PRKA) anchor protein 1
chrX_+_48554986 0.57 ENST00000376687.3
ENST00000453214.2
SUV39H1
suppressor of variegation 3-9 homolog 1 (Drosophila)
chr19_-_53193731 0.57 ENST00000598536.1
ENST00000594682.2
ENST00000601257.1
ZNF83
zinc finger protein 83
chr2_-_43823119 0.57 ENST00000403856.1
ENST00000404790.1
ENST00000405975.2
ENST00000415080.2
THADA
thyroid adenoma associated
chr1_+_111991474 0.56 ENST00000369722.3
ATP5F1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1
chr11_+_11863579 0.56 ENST00000399455.2
USP47
ubiquitin specific peptidase 47
chr2_+_189156721 0.56 ENST00000409927.1
ENST00000409805.1
GULP1
GULP, engulfment adaptor PTB domain containing 1
chr2_+_9563697 0.56 ENST00000238112.3
CPSF3
cleavage and polyadenylation specific factor 3, 73kDa
chr3_+_169684553 0.56 ENST00000337002.4
ENST00000480708.1
SEC62
SEC62 homolog (S. cerevisiae)
chr12_-_124018252 0.56 ENST00000376874.4
RILPL1
Rab interacting lysosomal protein-like 1
chr2_+_189156586 0.56 ENST00000409830.1
GULP1
GULP, engulfment adaptor PTB domain containing 1
chr17_+_74723031 0.55 ENST00000586200.1
METTL23
methyltransferase like 23
chr14_+_61447832 0.55 ENST00000354886.2
ENST00000267488.4
SLC38A6
solute carrier family 38, member 6
chr13_-_37633567 0.55 ENST00000464744.1
SUPT20H
suppressor of Ty 20 homolog (S. cerevisiae)
chr5_+_118407053 0.55 ENST00000311085.8
ENST00000539542.1
DMXL1
Dmx-like 1
chr9_+_86595626 0.54 ENST00000445877.1
ENST00000325875.3
RMI1
RecQ mediated genome instability 1
chr3_-_183735731 0.54 ENST00000334444.6
ABCC5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr5_-_39074479 0.54 ENST00000514735.1
ENST00000296782.5
ENST00000357387.3
RICTOR
RPTOR independent companion of MTOR, complex 2
chr2_+_9564013 0.54 ENST00000460593.1
CPSF3
cleavage and polyadenylation specific factor 3, 73kDa
chr4_+_170541660 0.52 ENST00000513761.1
ENST00000347613.4
CLCN3
chloride channel, voltage-sensitive 3
chr21_+_35445827 0.51 ENST00000608209.1
ENST00000381151.3
SLC5A3
SLC5A3
sodium/myo-inositol cotransporter
solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
chr7_-_158497431 0.51 ENST00000449727.2
ENST00000409339.3
ENST00000409423.1
ENST00000356309.3
NCAPG2
non-SMC condensin II complex, subunit G2
chr16_-_18801643 0.51 ENST00000322989.4
ENST00000563390.1
RPS15A
ribosomal protein S15a
chr5_+_134181755 0.51 ENST00000504727.1
ENST00000435259.2
ENST00000508791.1
C5orf24
chromosome 5 open reading frame 24
chr9_+_35792151 0.51 ENST00000342694.2
NPR2
natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
chr6_+_130686856 0.51 ENST00000296978.3
TMEM200A
transmembrane protein 200A
chr5_+_139493665 0.50 ENST00000331327.3
PURA
purine-rich element binding protein A
chr15_+_22833395 0.50 ENST00000283645.4
TUBGCP5
tubulin, gamma complex associated protein 5
chr21_+_34638656 0.49 ENST00000290200.2
IL10RB
interleukin 10 receptor, beta

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB33_CHD2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.0 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.7 3.4 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.7 2.0 GO:1902363 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.6 2.6 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
0.6 2.9 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.5 2.0 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.4 1.2 GO:0014016 neuroblast differentiation(GO:0014016)
0.4 1.1 GO:0035283 rhombomere 3 development(GO:0021569) rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.4 1.5 GO:1901895 negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.4 1.1 GO:0002188 translation reinitiation(GO:0002188)
0.3 8.9 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.3 2.7 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.3 2.9 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.3 0.9 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.3 1.5 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.3 0.6 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.3 0.8 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.3 0.8 GO:0042663 regulation of endodermal cell fate specification(GO:0042663) regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.3 2.2 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.3 1.6 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.3 1.1 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.3 0.8 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.2 0.7 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.2 0.7 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.2 1.0 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.2 0.6 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.2 0.4 GO:0007113 endomitotic cell cycle(GO:0007113)
0.2 1.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.2 0.5 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.2 0.9 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.2 0.7 GO:0006272 leading strand elongation(GO:0006272)
0.2 1.0 GO:0015853 adenine transport(GO:0015853)
0.2 1.7 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.2 1.0 GO:0048388 endosomal lumen acidification(GO:0048388)
0.2 0.6 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.2 0.5 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.2 0.6 GO:0036292 DNA rewinding(GO:0036292)
0.1 1.0 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641) negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1 0.6 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.1 1.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 0.4 GO:0071139 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.1 0.4 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.1 0.5 GO:0060283 negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.1 0.4 GO:1904815 negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
0.1 0.6 GO:0061760 antifungal innate immune response(GO:0061760)
0.1 0.5 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.1 1.9 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.7 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.6 GO:0051621 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.1 0.7 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.1 0.3 GO:0090235 regulation of metaphase plate congression(GO:0090235)
0.1 0.4 GO:0015917 aminophospholipid transport(GO:0015917)
0.1 0.4 GO:2000768 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.1 1.2 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.1 0.3 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.1 0.3 GO:1904437 positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440)
0.1 0.4 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.4 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.9 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.1 5.3 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.1 0.4 GO:1990637 response to prolactin(GO:1990637)
0.1 0.7 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.1 0.4 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
0.1 3.5 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 1.4 GO:0010566 regulation of ketone biosynthetic process(GO:0010566)
0.1 0.2 GO:0097187 dentinogenesis(GO:0097187)
0.1 0.5 GO:0015798 myo-inositol transport(GO:0015798)
0.1 1.1 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.7 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.1 1.1 GO:0015074 DNA integration(GO:0015074)
0.1 0.8 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.1 0.5 GO:0042335 cuticle development(GO:0042335)
0.1 0.5 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1 0.4 GO:0098728 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 0.6 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.1 0.4 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.1 0.4 GO:0018343 protein farnesylation(GO:0018343)
0.1 1.6 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 0.2 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1 0.9 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 0.9 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1 0.5 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.1 0.8 GO:0033227 dsRNA transport(GO:0033227)
0.1 0.6 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.1 1.5 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.1 0.6 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.1 0.2 GO:0006844 acyl carnitine transport(GO:0006844) acyl carnitine transmembrane transport(GO:1902616)
0.1 0.7 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.2 GO:0002572 pro-T cell differentiation(GO:0002572)
0.1 0.8 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.1 0.4 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
0.1 0.1 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
0.1 0.2 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.1 0.2 GO:0006850 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.1 0.5 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 0.4 GO:0001661 conditioned taste aversion(GO:0001661)
0.1 0.4 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.1 0.6 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 3.1 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.1 0.9 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.1 0.3 GO:0090650 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.1 0.5 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.0 0.3 GO:0042713 sperm ejaculation(GO:0042713)
0.0 0.3 GO:0085020 protein K6-linked ubiquitination(GO:0085020)
0.0 0.2 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.2 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.6 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 0.7 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.3 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.2 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.0 0.1 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
0.0 0.2 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.0 1.9 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.4 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.9 GO:0070987 error-free translesion synthesis(GO:0070987)
0.0 2.7 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.2 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.6 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.9 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.6 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.3 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.0 GO:0021539 subthalamus development(GO:0021539)
0.0 0.5 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.1 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.0 0.2 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.5 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.0 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0 0.6 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.7 GO:0039529 RIG-I signaling pathway(GO:0039529)
0.0 0.2 GO:0033131 regulation of glucokinase activity(GO:0033131) positive regulation of glucokinase activity(GO:0033133) regulation of hexokinase activity(GO:1903299) positive regulation of hexokinase activity(GO:1903301)
0.0 0.1 GO:0006535 cysteine biosynthetic process from serine(GO:0006535)
0.0 0.4 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.5 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.3 GO:0006528 asparagine metabolic process(GO:0006528)
0.0 0.1 GO:0003163 sinoatrial node development(GO:0003163) sinoatrial node cell differentiation(GO:0060921) sinoatrial node cell development(GO:0060931)
0.0 0.1 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.0 0.2 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.9 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.2 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.4 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.4 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.3 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.2 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.1 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0 0.5 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.3 GO:1902739 interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.0 0.2 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.0 0.1 GO:2001279 regulation of prostaglandin biosynthetic process(GO:0031392) regulation of unsaturated fatty acid biosynthetic process(GO:2001279)
0.0 0.1 GO:1903722 negative regulation of exosomal secretion(GO:1903542) regulation of centriole elongation(GO:1903722)
0.0 4.0 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.2 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.9 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.2 GO:0010767 regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010767) negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026) positive regulation of androgen receptor activity(GO:2000825)
0.0 0.4 GO:0015886 heme transport(GO:0015886)
0.0 0.3 GO:0097264 self proteolysis(GO:0097264)
0.0 0.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.2 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.1 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.4 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.3 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.1 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.1 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.0 0.9 GO:0006517 protein deglycosylation(GO:0006517)
0.0 0.2 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 3.0 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.6 GO:0016180 snRNA processing(GO:0016180)
0.0 0.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.2 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.3 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.0 0.7 GO:0010996 response to auditory stimulus(GO:0010996)
0.0 0.4 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 0.2 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.0 0.3 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.2 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097)
0.0 0.2 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.0 0.3 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.0 1.1 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.2 GO:0060312 regulation of blood vessel remodeling(GO:0060312)
0.0 0.3 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.7 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 0.1 GO:0035625 negative regulation of epinephrine secretion(GO:0032811) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.0 0.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.6 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.3 GO:0048681 negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
0.0 3.9 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 1.1 GO:0060416 response to growth hormone(GO:0060416)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.1 GO:1904457 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.0 0.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.2 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.4 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.1 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.3 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.0 0.5 GO:0014829 vascular smooth muscle contraction(GO:0014829)
0.0 0.3 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 1.7 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 1.0 GO:0021762 substantia nigra development(GO:0021762)
0.0 0.3 GO:0046931 pore complex assembly(GO:0046931)
0.0 0.2 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 1.3 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.0 0.3 GO:0009642 response to light intensity(GO:0009642)
0.0 0.3 GO:0006692 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.0 1.3 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.0 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.0 0.8 GO:0051145 smooth muscle cell differentiation(GO:0051145)
0.0 0.2 GO:0033523 histone H2B ubiquitination(GO:0033523)
0.0 0.2 GO:0040001 establishment of mitotic spindle localization(GO:0040001)
0.0 0.4 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.0 0.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.8 GO:0030071 regulation of mitotic metaphase/anaphase transition(GO:0030071)
0.0 0.4 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.3 GO:2000179 positive regulation of neural precursor cell proliferation(GO:2000179)
0.0 0.3 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.3 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.3 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0055028 cortical microtubule(GO:0055028)
0.6 2.3 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.4 3.9 GO:0000796 condensin complex(GO:0000796)
0.3 4.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.3 2.8 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.2 0.7 GO:1990716 axonemal central apparatus(GO:1990716)
0.2 2.1 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.2 1.0 GO:1990246 uniplex complex(GO:1990246)
0.2 0.7 GO:0031213 RSF complex(GO:0031213)
0.2 0.5 GO:0043291 RAVE complex(GO:0043291)
0.2 5.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.2 0.2 GO:1902636 kinociliary basal body(GO:1902636)
0.2 0.5 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.2 4.8 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 2.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 1.0 GO:1990393 3M complex(GO:1990393)
0.1 2.0 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.8 GO:0097422 tubular endosome(GO:0097422)
0.1 0.7 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 3.5 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 0.4 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.1 0.7 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.1 0.6 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 0.6 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.1 0.3 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.7 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.1 0.3 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.1 1.1 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 0.5 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.1 0.4 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.1 0.9 GO:0097470 ribbon synapse(GO:0097470)
0.1 0.3 GO:0031905 early endosome lumen(GO:0031905)
0.1 0.6 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.8 GO:0097433 dense body(GO:0097433)
0.1 1.1 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 0.5 GO:0061617 MICOS complex(GO:0061617)
0.1 0.5 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 0.6 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.5 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 0.4 GO:0035976 AP1 complex(GO:0035976)
0.1 1.0 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.1 0.5 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.4 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.2 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.6 GO:0032039 integrator complex(GO:0032039)
0.0 0.3 GO:0070847 core mediator complex(GO:0070847)
0.0 0.3 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.2 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0 0.7 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 1.6 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.7 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.6 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.5 GO:0000124 SAGA complex(GO:0000124)
0.0 2.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.9 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.3 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.3 GO:0071953 elastic fiber(GO:0071953)
0.0 1.3 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.6 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.4 GO:0070652 HAUS complex(GO:0070652)
0.0 2.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 2.2 GO:0000786 nucleosome(GO:0000786)
0.0 0.9 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.4 GO:0070187 telosome(GO:0070187)
0.0 1.3 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.2 GO:0071547 piP-body(GO:0071547)
0.0 1.0 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 0.3 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.4 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.4 GO:0097227 sperm annulus(GO:0097227)
0.0 0.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.2 GO:0032300 mismatch repair complex(GO:0032300)
0.0 0.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.5 GO:0031932 TORC2 complex(GO:0031932)
0.0 3.2 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.4 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.3 GO:0035631 IkappaB kinase complex(GO:0008385) CD40 receptor complex(GO:0035631)
0.0 0.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.6 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.1 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 1.8 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.6 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.0 GO:0034455 t-UTP complex(GO:0034455)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 3.0 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 2.8 GO:0000922 spindle pole(GO:0000922)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 1.3 GO:0005814 centriole(GO:0005814)
0.0 1.3 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 1.3 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 2.6 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.3 GO:0043596 nuclear replication fork(GO:0043596)
0.0 1.6 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 1.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 GO:0030626 U12 snRNA binding(GO:0030626)
0.4 1.2 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.3 1.4 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.3 4.4 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.3 1.2 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.3 3.2 GO:0051525 NFAT protein binding(GO:0051525)
0.2 0.6 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.2 2.9 GO:0051011 microtubule minus-end binding(GO:0051011)
0.2 2.0 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.2 0.7 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.2 1.5 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.2 0.5 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 1.0 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.2 3.9 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.2 0.5 GO:0090541 MIT domain binding(GO:0090541)
0.2 0.5 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.2 0.9 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.1 0.4 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.1 6.2 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.1 0.4 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 0.8 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 0.6 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 0.9 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 0.4 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.1 0.6 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 0.3 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.1 1.0 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 0.4 GO:0003978 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.1 0.4 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.1 0.6 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.3 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 0.6 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.3 GO:0016730 ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
0.1 0.7 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.1 0.9 GO:0015288 porin activity(GO:0015288)
0.1 0.4 GO:0031685 adenosine receptor binding(GO:0031685)
0.1 0.3 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.1 0.5 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 2.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.6 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 0.4 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.9 GO:0070569 uridylyltransferase activity(GO:0070569)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 2.8 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 0.4 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 0.3 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.8 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005) PH domain binding(GO:0042731)
0.1 0.6 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.1 2.9 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 0.7 GO:0009374 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.1 1.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.3 GO:0008384 IkappaB kinase activity(GO:0008384)
0.1 1.0 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.4 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 0.8 GO:0039706 co-receptor binding(GO:0039706)
0.1 0.3 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.1 0.2 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.1 0.5 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 2.1 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.3 GO:0008169 C-methyltransferase activity(GO:0008169)
0.1 0.2 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.1 0.2 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.1 0.5 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 0.4 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 0.5 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 0.9 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.1 0.8 GO:0034452 dynactin binding(GO:0034452)
0.1 0.5 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.6 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.7 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.3 GO:0047522 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 0.2 GO:0004803 transposase activity(GO:0004803)
0.0 0.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 1.1 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.5 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.0 0.3 GO:0043426 MRF binding(GO:0043426)
0.0 0.3 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.1 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 0.2 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 4.6 GO:0002039 p53 binding(GO:0002039)
0.0 0.3 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.4 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0 0.2 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.2 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.3 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.0 0.4 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.1 GO:0016662 cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
0.0 0.3 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.3 GO:0034711 activin-activated receptor activity(GO:0017002) inhibin binding(GO:0034711)
0.0 0.4 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.3 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.9 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.2 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.7 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.3 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.4 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.2 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 1.3 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.9 GO:0005521 lamin binding(GO:0005521)
0.0 0.7 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 1.0 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 1.0 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.1 GO:0038131 neuregulin receptor activity(GO:0038131)
0.0 0.2 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.4 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.7 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.2 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.7 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.2 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.0 0.1 GO:0004802 transketolase activity(GO:0004802)
0.0 0.3 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.7 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.1 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 0.1 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.2 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.8 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0015207 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.0 8.3 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.3 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.3 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 1.1 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.4 GO:0005542 folic acid binding(GO:0005542)
0.0 0.1 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.0 0.1 GO:1903136 cuprous ion binding(GO:1903136)
0.0 0.2 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.2 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.5 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.7 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 1.2 GO:0043621 protein self-association(GO:0043621)
0.0 0.4 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.4 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.6 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.4 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 0.3 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 9.6 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 1.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0034979 NAD-dependent protein deacetylase activity(GO:0034979)
0.0 0.3 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 3.5 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 0.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.7 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.1 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.6 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.3 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.0 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
0.0 0.0 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.0 0.1 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.5 PID S1P S1P2 PATHWAY S1P2 pathway
0.1 0.3 PID BARD1 PATHWAY BARD1 signaling events
0.1 0.5 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 5.5 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.6 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 1.2 ST GA12 PATHWAY G alpha 12 Pathway
0.0 2.7 PID AURORA B PATHWAY Aurora B signaling
0.0 2.1 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.4 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 1.4 PID MYC PATHWAY C-MYC pathway
0.0 1.6 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.3 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.5 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.2 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.1 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.0 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 1.2 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 1.1 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.8 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.8 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.8 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.3 ST ADRENERGIC Adrenergic Pathway
0.0 0.2 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.5 PID TGFBR PATHWAY TGF-beta receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.4 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 2.7 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 0.3 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 1.6 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 1.1 REACTOME DEVELOPMENTAL BIOLOGY Genes involved in Developmental Biology
0.1 2.0 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.1 1.9 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 1.5 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 1.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 4.2 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 1.0 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 1.1 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 1.6 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.7 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.4 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.0 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.2 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.6 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 1.2 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 2.5 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 2.2 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.7 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.3 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.9 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.9 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 1.7 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.9 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 1.1 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.1 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.5 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.4 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.8 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.6 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.9 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.5 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis