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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for ZBTB4

Z-value: 0.37

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Transcription factors associated with ZBTB4

Gene Symbol Gene ID Gene Info
ENSG00000174282.7 zinc finger and BTB domain containing 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZBTB4hg19_v2_chr17_-_7387524_7387597,
hg19_v2_chr17_-_7382834_7382855
-0.321.2e-01Click!

Activity profile of ZBTB4 motif

Sorted Z-values of ZBTB4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_72385437 1.19 ENST00000418754.2
ENST00000542969.2
ENST00000334456.5
phosphodiesterase 2A, cGMP-stimulated
chr1_+_169075554 0.84 ENST00000367815.4
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr10_-_101380121 0.81 ENST00000370495.4
solute carrier family 25 (mitochondrial iron transporter), member 28
chr17_-_40264692 0.50 ENST00000591220.1
ENST00000251642.3
DEXH (Asp-Glu-X-His) box polypeptide 58
chr11_+_86511549 0.44 ENST00000533902.2
protease, serine, 23
chrX_-_68385354 0.43 ENST00000361478.1
praja ring finger 1, E3 ubiquitin protein ligase
chrX_-_68385274 0.43 ENST00000374584.3
ENST00000590146.1
praja ring finger 1, E3 ubiquitin protein ligase
chr13_-_44361025 0.39 ENST00000261488.6
ecto-NOX disulfide-thiol exchanger 1
chr13_-_33780133 0.38 ENST00000399365.3
StAR-related lipid transfer (START) domain containing 13
chr15_-_40212363 0.37 ENST00000299092.3
G protein-coupled receptor 176
chr15_-_40213080 0.35 ENST00000561100.1
G protein-coupled receptor 176
chr16_-_87903079 0.32 ENST00000261622.4
solute carrier family 7 (amino acid transporter light chain, L system), member 5
chr1_-_203055129 0.31 ENST00000241651.4
myogenin (myogenic factor 4)
chr11_+_62623544 0.28 ENST00000377890.2
ENST00000377891.2
ENST00000377889.2
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr3_-_192635943 0.28 ENST00000392452.2
Mab-21 domain containing 2
chr11_+_62623512 0.27 ENST00000377892.1
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr10_+_37414785 0.26 ENST00000374660.1
ENST00000602533.1
ENST00000361713.1
ankyrin repeat domain 30A
chr5_-_146889619 0.26 ENST00000343218.5
dihydropyrimidinase-like 3
chr14_-_85996332 0.26 ENST00000380722.1
RP11-497E19.1
chr16_-_79634595 0.25 ENST00000326043.4
ENST00000393350.1
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
chr16_-_89556942 0.23 ENST00000301030.4
ankyrin repeat domain 11
chr8_+_94929077 0.23 ENST00000297598.4
ENST00000520614.1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr11_+_86511569 0.22 ENST00000441050.1
protease, serine, 23
chr17_-_30185946 0.22 ENST00000579741.1
coordinator of PRMT5, differentiation stimulator
chr22_+_29279552 0.21 ENST00000544604.2
zinc and ring finger 3
chr4_-_7069760 0.21 ENST00000264954.4
GrpE-like 1, mitochondrial (E. coli)
chr1_+_166808692 0.21 ENST00000367876.4
pogo transposable element with KRAB domain
chr7_-_18067478 0.21 ENST00000506618.2
phosphoribosyl pyrophosphate synthetase 1-like 1
chr14_-_69445793 0.21 ENST00000538545.2
ENST00000394419.4
actinin, alpha 1
chr14_+_74417192 0.21 ENST00000554320.1
coenzyme Q6 monooxygenase
chr8_+_94929110 0.20 ENST00000520728.1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr8_-_71581377 0.20 ENST00000276590.4
ENST00000522447.1
lactamase, beta 2
chr5_-_96143796 0.20 ENST00000296754.3
endoplasmic reticulum aminopeptidase 1
chr11_+_33902189 0.19 ENST00000330381.2
HCG1785179; PRO1787; Uncharacterized protein
chr6_-_136847610 0.19 ENST00000454590.1
ENST00000432797.2
microtubule-associated protein 7
chr6_+_159290917 0.19 ENST00000367072.1
chromosome 6 open reading frame 99
chr11_-_63439381 0.19 ENST00000538786.1
ENST00000540699.1
atlastin GTPase 3
chr11_+_65082289 0.19 ENST00000279249.2
CDC42 effector protein (Rho GTPase binding) 2
chr1_-_156786530 0.18 ENST00000368198.3
SH2 domain containing 2A
chr9_+_4792971 0.18 ENST00000381732.3
ENST00000442869.1
RNA terminal phosphate cyclase-like 1
chr22_-_50970919 0.17 ENST00000329363.4
ENST00000437588.1
outer dense fiber of sperm tails 3B
chrX_-_71526813 0.17 ENST00000246139.5
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chr5_-_115177247 0.17 ENST00000500945.2
autophagy related 12
chr6_+_31582961 0.17 ENST00000376059.3
ENST00000337917.7
allograft inflammatory factor 1
chr3_-_167452703 0.17 ENST00000497056.2
ENST00000473645.2
programmed cell death 10
chr1_-_151254362 0.17 ENST00000447795.2
Uncharacterized protein
chr16_-_11370330 0.17 ENST00000241808.4
ENST00000435245.2
protamine 2
chr2_+_192110199 0.17 ENST00000304164.4
myosin IB
chr7_+_87257854 0.16 ENST00000394654.3
RUN domain containing 3B
chr11_+_120973375 0.16 ENST00000264037.2
tectorin alpha
chr13_+_24734880 0.16 ENST00000382095.4
spermatogenesis associated 13
chr16_-_30042580 0.16 ENST00000380495.4
family with sequence similarity 57, member B
chr19_+_17830051 0.16 ENST00000594625.1
ENST00000324096.4
ENST00000600186.1
ENST00000597735.1
microtubule-associated protein 1S
chr15_-_98417780 0.15 ENST00000503874.3
long intergenic non-protein coding RNA 923
chr11_+_125462690 0.15 ENST00000392708.4
ENST00000529196.1
ENST00000531491.1
STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
chr3_-_167452614 0.15 ENST00000392750.2
ENST00000464360.1
ENST00000492139.1
ENST00000471885.1
ENST00000470131.1
programmed cell death 10
chr17_-_5389477 0.15 ENST00000572834.1
ENST00000570848.1
ENST00000571971.1
ENST00000158771.4
derlin 2
chr2_+_192109911 0.15 ENST00000418908.1
ENST00000339514.4
ENST00000392318.3
myosin IB
chr17_-_30185971 0.15 ENST00000378634.2
coordinator of PRMT5, differentiation stimulator
chr19_+_6135646 0.15 ENST00000588304.1
ENST00000588485.1
ENST00000588722.1
ENST00000591403.1
ENST00000586696.1
ENST00000589401.1
ENST00000252669.5
acyl-CoA synthetase bubblegum family member 2
chr17_-_48943706 0.15 ENST00000499247.2
transducer of ERBB2, 1
chr6_-_114664180 0.15 ENST00000312719.5
heparan sulfate (glucosamine) 3-O-sulfotransferase 5
chr8_+_94929168 0.14 ENST00000518107.1
ENST00000396200.3
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr22_-_50970506 0.14 ENST00000428989.2
ENST00000403326.1
outer dense fiber of sperm tails 3B
chr4_+_71554196 0.14 ENST00000254803.2
UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)
chr3_+_113666748 0.14 ENST00000330212.3
ENST00000498275.1
zinc finger, DHHC-type containing 23
chr10_+_123922941 0.14 ENST00000360561.3
transforming, acidic coiled-coil containing protein 2
chr1_-_33283754 0.14 ENST00000373477.4
tyrosyl-tRNA synthetase
chrX_-_74145273 0.14 ENST00000055682.6
KIAA2022
chr16_+_640201 0.13 ENST00000563109.1
RAB40C, member RAS oncogene family
chr3_+_40518599 0.13 ENST00000314686.5
ENST00000447116.2
ENST00000429348.2
ENST00000456778.1
zinc finger protein 619
chr19_-_10530784 0.13 ENST00000593124.1
cell division cycle 37
chr7_-_5463175 0.13 ENST00000399537.4
ENST00000430969.1
trinucleotide repeat containing 18
chr17_-_2996290 0.13 ENST00000331459.1
olfactory receptor, family 1, subfamily D, member 2
chr15_-_75660919 0.13 ENST00000569482.1
ENST00000565683.1
ENST00000561615.1
ENST00000563622.1
ENST00000568374.1
ENST00000566256.1
ENST00000267978.5
mannosidase, alpha, class 2C, member 1
chr17_-_30186328 0.13 ENST00000302362.6
coordinator of PRMT5, differentiation stimulator
chr13_-_24007815 0.13 ENST00000382298.3
spastic ataxia of Charlevoix-Saguenay (sacsin)
chr17_-_56595196 0.12 ENST00000579921.1
ENST00000579925.1
ENST00000323456.5
myotubularin related protein 4
chr1_-_151299842 0.12 ENST00000438243.2
ENST00000489223.2
ENST00000368873.1
ENST00000430800.1
ENST00000368872.1
phosphatidylinositol 4-kinase, catalytic, beta
chr1_+_200842083 0.12 ENST00000304244.2
G protein-coupled receptor 25
chr3_-_119813264 0.12 ENST00000264235.8
glycogen synthase kinase 3 beta
chr16_-_30538079 0.12 ENST00000562803.1
zinc finger protein 768
chr17_+_54671047 0.12 ENST00000332822.4
noggin
chr9_-_131709858 0.11 ENST00000372586.3
dolichol kinase
chr1_+_110163709 0.11 ENST00000369840.2
ENST00000527846.1
adenosine monophosphate deaminase 2
chr9_-_80263220 0.11 ENST00000341700.6
guanine nucleotide binding protein (G protein), alpha 14
chr17_+_34058639 0.11 ENST00000268864.3
RAS-like, family 10, member B
chr14_-_74417096 0.11 ENST00000286544.3
family with sequence similarity 161, member B
chr14_-_69445968 0.11 ENST00000438964.2
actinin, alpha 1
chr20_+_61147651 0.11 ENST00000370527.3
ENST00000370524.2
chromosome 20 open reading frame 166
chr18_-_55253871 0.11 ENST00000382873.3
ferrochelatase
chr19_+_39421556 0.11 ENST00000407800.2
ENST00000402029.3
mitochondrial ribosomal protein S12
chr8_-_143851203 0.11 ENST00000521396.1
ENST00000317543.7
Ly6/neurotoxin 1
chr19_+_19144384 0.10 ENST00000392335.2
ENST00000535612.1
ENST00000537263.1
ENST00000540707.1
ENST00000541725.1
ENST00000269932.6
ENST00000546344.1
ENST00000540792.1
ENST00000536098.1
ENST00000541898.1
ENST00000543877.1
armadillo repeat containing 6
chr12_+_5541267 0.10 ENST00000423158.3
neurotrophin 3
chr7_-_128694927 0.10 ENST00000471166.1
ENST00000265388.5
transportin 3
chr6_+_31583761 0.10 ENST00000376049.4
allograft inflammatory factor 1
chr11_-_73471655 0.10 ENST00000400470.2
RAB6A, member RAS oncogene family
chr7_-_44613494 0.10 ENST00000431640.1
ENST00000258772.5
DEAD (Asp-Glu-Ala-Asp) box helicase 56
chr10_-_103599591 0.10 ENST00000348850.5
Kv channel interacting protein 2
chr17_+_5389605 0.10 ENST00000576988.1
ENST00000576570.1
ENST00000573759.1
MIS12 kinetochore complex component
chr19_+_47759716 0.09 ENST00000221922.6
coiled-coil domain containing 9
chr3_-_57583130 0.09 ENST00000303436.6
ADP-ribosylation factor 4
chr19_-_50316517 0.09 ENST00000313777.4
ENST00000445575.2
fuzzy planar cell polarity protein
chr11_-_61735029 0.09 ENST00000526640.1
ferritin, heavy polypeptide 1
chrX_-_47509887 0.09 ENST00000247161.3
ENST00000592066.1
ENST00000376983.3
ELK1, member of ETS oncogene family
chr9_-_128246769 0.09 ENST00000444226.1
mitogen-activated protein kinase associated protein 1
chr7_-_100487280 0.08 ENST00000388761.2
UFM1-specific peptidase 1 (non-functional)
chr19_+_10828795 0.08 ENST00000389253.4
ENST00000355667.6
ENST00000408974.4
dynamin 2
chr4_-_156298087 0.08 ENST00000311277.4
microtubule-associated protein 9
chr6_-_48036363 0.08 ENST00000543600.1
ENST00000398738.2
ENST00000339488.4
patched domain containing 4
chr1_-_160549235 0.08 ENST00000368054.3
ENST00000368048.3
ENST00000311224.4
ENST00000368051.3
ENST00000534968.1
CD84 molecule
chr4_-_156297949 0.08 ENST00000515654.1
microtubule-associated protein 9
chr19_+_36024310 0.08 ENST00000222286.4
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr14_-_35099377 0.08 ENST00000362031.4
sorting nexin 6
chr11_+_107799118 0.08 ENST00000320578.2
RAB39A, member RAS oncogene family
chr3_-_57583052 0.08 ENST00000496292.1
ENST00000489843.1
ADP-ribosylation factor 4
chr19_+_10531150 0.08 ENST00000352831.6
phosphodiesterase 4A, cAMP-specific
chr19_+_10828724 0.08 ENST00000585892.1
ENST00000314646.5
ENST00000359692.6
dynamin 2
chr14_-_35099315 0.08 ENST00000396526.3
ENST00000396534.3
ENST00000355110.5
ENST00000557265.1
sorting nexin 6
chr17_+_72270380 0.08 ENST00000582036.1
ENST00000307504.5
dynein, axonemal, intermediate chain 2
chr2_+_152266392 0.08 ENST00000444746.2
ENST00000453091.2
ENST00000428287.2
ENST00000433166.2
ENST00000420714.3
ENST00000243326.5
ENST00000414861.2
RAP1 interacting factor homolog (yeast)
chr22_-_50970566 0.07 ENST00000405135.1
ENST00000401779.1
outer dense fiber of sperm tails 3B
chr16_-_22385901 0.07 ENST00000268383.2
cerebellar degeneration-related protein 2, 62kDa
chr8_+_57124245 0.07 ENST00000521831.1
ENST00000355315.3
ENST00000303759.3
ENST00000517636.1
ENST00000517933.1
ENST00000518801.1
ENST00000523975.1
ENST00000396723.5
ENST00000523061.1
ENST00000521524.1
coiled-coil-helix-coiled-coil-helix domain containing 7
chrX_+_147582130 0.07 ENST00000370460.2
ENST00000370457.5
AF4/FMR2 family, member 2
chr11_-_63439174 0.07 ENST00000332645.4
atlastin GTPase 3
chr7_+_87257701 0.07 ENST00000338056.3
ENST00000493037.1
RUN domain containing 3B
chr3_-_57583185 0.07 ENST00000463880.1
ADP-ribosylation factor 4
chr14_+_55494323 0.06 ENST00000339298.2
suppressor of cytokine signaling 4
chr2_+_155554797 0.06 ENST00000295101.2
potassium inwardly-rectifying channel, subfamily J, member 3
chr1_+_10534944 0.06 ENST00000356607.4
ENST00000538836.1
ENST00000491661.2
peroxisomal biogenesis factor 14
chr9_-_136242956 0.06 ENST00000371989.3
ENST00000485435.2
surfeit 4
chr16_+_640055 0.06 ENST00000568586.1
ENST00000538492.1
ENST00000248139.3
RAB40C, member RAS oncogene family
chr4_-_113437328 0.06 ENST00000313341.3
neurogenin 2
chr1_-_32403370 0.06 ENST00000534796.1
protein tyrosine phosphatase type IVA, member 2
chr1_-_165738072 0.06 ENST00000481278.1
transmembrane and coiled-coil domains 1
chr4_+_4388805 0.06 ENST00000504171.1
Homo sapiens neuron specific gene family member 1 (NSG1), transcript variant 3, mRNA.
chr15_-_44116873 0.06 ENST00000267812.3
microfibrillar-associated protein 1
chr1_-_38325256 0.06 ENST00000373036.4
metal-regulatory transcription factor 1
chr14_+_55493920 0.06 ENST00000395472.2
ENST00000555846.1
suppressor of cytokine signaling 4
chr14_+_74416989 0.06 ENST00000334571.2
ENST00000554920.1
coenzyme Q6 monooxygenase
chr17_+_45727204 0.06 ENST00000290158.4
karyopherin (importin) beta 1
chr2_-_180871780 0.06 ENST00000410053.3
ENST00000295749.6
ENST00000404136.2
CWC22 spliceosome-associated protein homolog (S. cerevisiae)
chr19_+_1275917 0.06 ENST00000469144.1
chromosome 19 open reading frame 24
chr2_+_232651124 0.06 ENST00000350033.3
ENST00000412591.1
ENST00000410017.1
ENST00000373608.3
COP9 signalosome subunit 7B
chr14_+_23305760 0.06 ENST00000311852.6
matrix metallopeptidase 14 (membrane-inserted)
chr12_+_6561190 0.05 ENST00000544021.1
ENST00000266556.7
TAP binding protein-like
chr2_-_207024233 0.05 ENST00000423725.1
ENST00000233190.6
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr20_-_43438912 0.05 ENST00000541604.2
ENST00000372851.3
regulating synaptic membrane exocytosis 4
chr6_+_158244223 0.05 ENST00000392185.3
sorting nexin 9
chr19_+_52074502 0.05 ENST00000545217.1
ENST00000262259.2
ENST00000596504.1
zinc finger protein 175
chr8_-_74205851 0.05 ENST00000396467.1
ribosomal protein L7
chr8_-_29208183 0.05 ENST00000240100.2
dual specificity phosphatase 4
chr9_-_130497565 0.05 ENST00000336067.6
ENST00000373281.5
ENST00000373284.5
ENST00000458505.3
torsin family 2, member A
chr9_+_33290491 0.05 ENST00000379540.3
ENST00000379521.4
ENST00000318524.6
nuclear transcription factor, X-box binding 1
chr7_+_102937869 0.05 ENST00000249269.4
ENST00000428154.1
ENST00000420236.2
peptidase (mitochondrial processing) beta
chr19_-_20748541 0.05 ENST00000427401.4
ENST00000594419.1
zinc finger protein 737
chr17_-_19265855 0.04 ENST00000440841.1
ENST00000395615.1
ENST00000461069.2
B9 protein domain 1
chr19_-_50316489 0.04 ENST00000533418.1
fuzzy planar cell polarity protein
chr11_-_63439013 0.04 ENST00000398868.3
atlastin GTPase 3
chr17_+_55334364 0.04 ENST00000322684.3
ENST00000579590.1
musashi RNA-binding protein 2
chr12_-_91348949 0.04 ENST00000358859.2
coiled-coil glutamate-rich protein 1
chr19_+_20959142 0.04 ENST00000344519.8
zinc finger protein 66
chr9_-_71629010 0.04 ENST00000377276.2
protein kinase, cAMP-dependent, catalytic, gamma
chr2_-_201936302 0.04 ENST00000453765.1
ENST00000452799.1
ENST00000446678.1
ENST00000418596.3
family with sequence similarity 126, member B
chr8_-_16859690 0.04 ENST00000180166.5
fibroblast growth factor 20
chr19_-_50316423 0.04 ENST00000528094.1
ENST00000526575.1
fuzzy planar cell polarity protein
chr1_+_151043070 0.04 ENST00000368918.3
ENST00000368917.1
GA binding protein transcription factor, beta subunit 2
chr4_-_83295103 0.04 ENST00000313899.7
ENST00000352301.4
ENST00000509107.1
ENST00000353341.4
ENST00000541060.1
heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
chr12_-_49525175 0.04 ENST00000336023.5
ENST00000550367.1
ENST00000552984.1
ENST00000547476.1
tubulin, alpha 1b
chr2_-_191399426 0.04 ENST00000409150.3
transmembrane protein 194B
chr10_-_53459319 0.03 ENST00000331173.4
cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
chr2_-_203735976 0.03 ENST00000435143.1
islet cell autoantigen 1,69kDa-like
chr14_-_50559361 0.03 ENST00000305273.1
chromosome 14 open reading frame 183
chr22_+_21987005 0.03 ENST00000607942.1
ENST00000425975.1
ENST00000292779.3
coiled-coil domain containing 116
chr12_+_52282001 0.03 ENST00000340970.4
ankyrin repeat domain 33
chr3_+_188889737 0.03 ENST00000345063.3
tumor protein p63 regulated 1
chr19_+_15121532 0.03 ENST00000292574.3
coiled-coil domain containing 105
chr12_+_106751436 0.02 ENST00000228347.4
polymerase (RNA) III (DNA directed) polypeptide B
chr12_-_46385811 0.02 ENST00000419565.2
SR-related CTD-associated factor 11
chr19_-_38714847 0.02 ENST00000420980.2
ENST00000355526.4
D4, zinc and double PHD fingers family 1
chr19_+_10217364 0.02 ENST00000430370.1
peter pan homolog (Drosophila)
chrX_+_153237740 0.02 ENST00000369982.4
transmembrane protein 187
chr12_+_52281744 0.02 ENST00000301190.6
ENST00000538991.1
ankyrin repeat domain 33
chr5_+_173416162 0.02 ENST00000340147.6
chromosome 5 open reading frame 47
chr1_+_43148625 0.02 ENST00000436427.1
Y box binding protein 1
chr3_-_71802760 0.02 ENST00000295612.3
eukaryotic translation initiation factor 4E family member 3
chr17_+_7487146 0.02 ENST00000396501.4
ENST00000584378.1
ENST00000423172.2
ENST00000579445.1
ENST00000585217.1
ENST00000581380.1
mannose-P-dolichol utilization defect 1
chr4_+_183370146 0.02 ENST00000510504.1
teneurin transmembrane protein 3
chr15_+_90792760 0.01 ENST00000339615.5
ENST00000438251.1
tubulin tyrosine ligase-like family, member 13
chr22_-_43411106 0.01 ENST00000453643.1
ENST00000263246.3
ENST00000337959.4
protein kinase C and casein kinase substrate in neurons 2
chr15_+_73735490 0.01 ENST00000331090.6
ENST00000560581.1
chromosome 15 open reading frame 60
chr15_+_42697065 0.01 ENST00000565559.1
calpain 3, (p94)
chr19_-_18902106 0.01 ENST00000542601.2
ENST00000425807.1
ENST00000222271.2
cartilage oligomeric matrix protein
chr10_+_121485588 0.01 ENST00000361976.2
ENST00000369083.3
inositol polyphosphate-5-phosphatase F
chr13_-_50018140 0.01 ENST00000410043.1
ENST00000347776.5
calcium binding protein 39-like
chr1_+_43148059 0.01 ENST00000321358.7
ENST00000332220.6
Y box binding protein 1
chr1_-_67896095 0.00 ENST00000370994.4
SERPINE1 mRNA binding protein 1
chr15_+_91498089 0.00 ENST00000394258.2
ENST00000555155.1
RCC1 domain containing 1

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.3 0.8 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.2 0.8 GO:1903281 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281) positive regulation of potassium ion import(GO:1903288)
0.1 0.5 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534) positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1 0.6 GO:0060356 leucine import(GO:0060356)
0.1 0.4 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 0.3 GO:0014878 regulation of muscle atrophy(GO:0014735) response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878) positive regulation of oxidative phosphorylation(GO:1903862)
0.1 0.3 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.1 0.3 GO:0014738 regulation of muscle hyperplasia(GO:0014738)
0.1 0.3 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.1 0.2 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.1 0.2 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.5 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.2 GO:2000051 Wnt receptor catabolic process(GO:0038018) negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.2 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.1 GO:0071109 superior temporal gyrus development(GO:0071109) negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.0 0.6 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.0 0.1 GO:0070541 response to platinum ion(GO:0070541)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.2 GO:0071105 response to interleukin-11(GO:0071105)
0.0 0.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.6 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.2 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.2 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.1 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.0 0.2 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.1 GO:0002590 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590)
0.0 0.1 GO:0060988 lipid tube assembly(GO:0060988)
0.0 0.1 GO:0032661 regulation of interleukin-18 production(GO:0032661)
0.0 0.2 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.2 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.1 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.0 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
0.0 0.2 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0006489 dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.0 0.1 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0 0.1 GO:0032264 IMP salvage(GO:0032264)
0.0 0.1 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.7 GO:0030818 negative regulation of cAMP biosynthetic process(GO:0030818)
0.0 0.1 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.1 GO:1990834 response to odorant(GO:1990834)
0.0 0.3 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.1 GO:1902373 negative regulation of mRNA catabolic process(GO:1902373)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.8 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.1 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.0 0.2 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.1 GO:0017102 methionyl glutamyl tRNA synthetase complex(GO:0017102)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.2 GO:0097422 tubular endosome(GO:0097422)
0.0 0.1 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 0.3 GO:0005916 fascia adherens(GO:0005916)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.4 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.4 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.1 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.1 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.1 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 0.6 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.2 GO:0005151 interleukin-1, Type II receptor binding(GO:0005151)
0.0 0.8 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.8 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.2 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.0 0.6 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.2 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.2 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.0 0.2 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.2 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.1 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.2 GO:0046870 cadmium ion binding(GO:0046870)
0.0 0.1 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.1 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.0 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.1 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.1 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.3 GO:0017166 vinculin binding(GO:0017166)
0.0 0.2 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.1 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.7 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.6 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane