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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for ZBTB6

Z-value: 1.11

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Transcription factors associated with ZBTB6

Gene Symbol Gene ID Gene Info
ZBTB6
ENSG00000186130.4 zinc finger and BTB domain containing 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZBTB6hg19_v2_chr9_-_125675576_1256756120.029.1e-01Click!

Activity profile of ZBTB6 motif

Sorted Z-values of ZBTB6 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_2039946 1.70 ENST00000248121.2
ENST00000568896.1
SYNGR3
synaptogyrin 3
chr1_+_101361782 1.39 ENST00000357650.4
SLC30A7
solute carrier family 30 (zinc transporter), member 7
chr5_-_149682447 1.13 ENST00000328668.7
ARSI
arylsulfatase family, member I
chr5_-_179780312 1.08 ENST00000253778.8
GFPT2
glutamine-fructose-6-phosphate transaminase 2
chr17_-_1733114 1.07 ENST00000305513.7
SMYD4
SET and MYND domain containing 4
chr9_-_123691047 1.06 ENST00000373887.3
TRAF1
TNF receptor-associated factor 1
chr3_-_116163830 1.05 ENST00000333617.4
LSAMP
limbic system-associated membrane protein
chr20_-_48532046 1.05 ENST00000543716.1
SPATA2
spermatogenesis associated 2
chr2_-_233352531 0.97 ENST00000304546.1
ECEL1
endothelin converting enzyme-like 1
chr11_-_615570 0.95 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
IRF7
interferon regulatory factor 7
chr1_+_26737253 0.93 ENST00000326279.6
LIN28A
lin-28 homolog A (C. elegans)
chr3_-_190040223 0.93 ENST00000295522.3
CLDN1
claudin 1
chr8_+_104513086 0.92 ENST00000406091.3
RIMS2
regulating synaptic membrane exocytosis 2
chr12_-_50298000 0.92 ENST00000550635.2
FAIM2
Fas apoptotic inhibitory molecule 2
chr11_+_71709938 0.91 ENST00000393705.4
ENST00000337131.5
ENST00000531053.1
ENST00000404792.1
IL18BP
interleukin 18 binding protein
chr10_-_121296045 0.90 ENST00000392865.1
RGS10
regulator of G-protein signaling 10
chr10_-_105615164 0.89 ENST00000355946.2
ENST00000369774.4
SH3PXD2A
SH3 and PX domains 2A
chr7_-_107880508 0.88 ENST00000425651.2
NRCAM
neuronal cell adhesion molecule
chr1_+_26737292 0.87 ENST00000254231.4
LIN28A
lin-28 homolog A (C. elegans)
chr8_+_23430157 0.85 ENST00000399967.3
FP15737
FP15737
chr6_+_149068464 0.85 ENST00000367463.4
UST
uronyl-2-sulfotransferase
chr10_+_81892347 0.83 ENST00000372267.2
PLAC9
placenta-specific 9
chr1_-_223537401 0.80 ENST00000343846.3
ENST00000454695.2
ENST00000484758.2
SUSD4
sushi domain containing 4
chr3_+_140770183 0.80 ENST00000310546.2
SPSB4
splA/ryanodine receptor domain and SOCS box containing 4
chr16_+_56659687 0.79 ENST00000568293.1
ENST00000330439.6
MT1E
metallothionein 1E
chr19_-_10464570 0.79 ENST00000529739.1
TYK2
tyrosine kinase 2
chr7_-_150864635 0.78 ENST00000297537.4
GBX1
gastrulation brain homeobox 1
chr16_+_50776021 0.77 ENST00000566679.2
ENST00000564634.1
ENST00000398568.2
CYLD
cylindromatosis (turban tumor syndrome)
chr7_-_105319536 0.75 ENST00000477775.1
ATXN7L1
ataxin 7-like 1
chr17_+_28256874 0.74 ENST00000541045.1
ENST00000536908.2
EFCAB5
EF-hand calcium binding domain 5
chr1_+_28199047 0.74 ENST00000373925.1
ENST00000328928.7
ENST00000373927.3
ENST00000427466.1
ENST00000442118.1
ENST00000373921.3
THEMIS2
thymocyte selection associated family member 2
chr17_-_49198095 0.73 ENST00000505279.1
SPAG9
sperm associated antigen 9
chr1_+_205197304 0.72 ENST00000358024.3
TMCC2
transmembrane and coiled-coil domain family 2
chr10_-_15413035 0.71 ENST00000378116.4
ENST00000455654.1
FAM171A1
family with sequence similarity 171, member A1
chr8_-_21646311 0.69 ENST00000524240.1
ENST00000400782.4
GFRA2
GDNF family receptor alpha 2
chr9_-_123691439 0.69 ENST00000540010.1
TRAF1
TNF receptor-associated factor 1
chr3_+_141594966 0.69 ENST00000475483.1
ATP1B3
ATPase, Na+/K+ transporting, beta 3 polypeptide
chr9_-_117150303 0.68 ENST00000312033.3
AKNA
AT-hook transcription factor
chr5_-_131563501 0.67 ENST00000401867.1
ENST00000379086.1
ENST00000418055.1
ENST00000453286.1
ENST00000166534.4
P4HA2
prolyl 4-hydroxylase, alpha polypeptide II
chr17_-_7232585 0.65 ENST00000571887.1
ENST00000315614.7
ENST00000399464.2
ENST00000570460.1
NEURL4
neuralized E3 ubiquitin protein ligase 4
chr10_+_114135952 0.65 ENST00000356116.1
ENST00000433418.1
ENST00000354273.4
ACSL5
acyl-CoA synthetase long-chain family member 5
chr10_+_72575643 0.64 ENST00000373202.3
SGPL1
sphingosine-1-phosphate lyase 1
chr19_-_6424783 0.64 ENST00000398148.3
KHSRP
KH-type splicing regulatory protein
chr8_-_72756667 0.63 ENST00000325509.4
MSC
musculin
chr17_+_34058639 0.63 ENST00000268864.3
RASL10B
RAS-like, family 10, member B
chr20_+_44486246 0.63 ENST00000255152.2
ENST00000454862.2
ZSWIM3
zinc finger, SWIM-type containing 3
chr8_+_63161491 0.62 ENST00000523211.1
ENST00000524201.1
NKAIN3
Na+/K+ transporting ATPase interacting 3
chr16_+_50775971 0.61 ENST00000311559.9
ENST00000564326.1
ENST00000566206.1
CYLD
cylindromatosis (turban tumor syndrome)
chr5_-_159546396 0.61 ENST00000523662.1
ENST00000456329.3
ENST00000307063.7
PWWP2A
PWWP domain containing 2A
chr14_+_59104741 0.61 ENST00000395153.3
ENST00000335867.4
DACT1
dishevelled-binding antagonist of beta-catenin 1
chr1_+_40627038 0.61 ENST00000372771.4
RLF
rearranged L-myc fusion
chr12_+_54943134 0.59 ENST00000243052.3
PDE1B
phosphodiesterase 1B, calmodulin-dependent
chr10_-_75571566 0.58 ENST00000299641.4
NDST2
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
chr5_+_17217669 0.58 ENST00000322611.3
BASP1
brain abundant, membrane attached signal protein 1
chr10_-_75571341 0.58 ENST00000309979.6
NDST2
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
chr12_-_6809543 0.58 ENST00000540656.1
PIANP
PILR alpha associated neural protein
chr17_+_46985731 0.57 ENST00000360943.5
UBE2Z
ubiquitin-conjugating enzyme E2Z
chr9_-_117150243 0.57 ENST00000374088.3
AKNA
AT-hook transcription factor
chr16_-_67281413 0.57 ENST00000258201.4
FHOD1
formin homology 2 domain containing 1
chr16_-_31021921 0.57 ENST00000215095.5
STX1B
syntaxin 1B
chr4_+_2061119 0.56 ENST00000423729.2
NAT8L
N-acetyltransferase 8-like (GCN5-related, putative)
chrX_+_131157290 0.56 ENST00000394334.2
MST4
Serine/threonine-protein kinase MST4
chr6_+_29691056 0.55 ENST00000414333.1
ENST00000334668.4
ENST00000259951.7
HLA-F
major histocompatibility complex, class I, F
chr20_-_48532019 0.55 ENST00000289431.5
SPATA2
spermatogenesis associated 2
chr12_+_7941989 0.53 ENST00000229307.4
NANOG
Nanog homeobox
chr1_-_156721502 0.52 ENST00000357325.5
HDGF
hepatoma-derived growth factor
chr1_+_45965725 0.52 ENST00000401061.4
MMACHC
methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
chr3_+_48507621 0.52 ENST00000456089.1
TREX1
three prime repair exonuclease 1
chr19_+_46367518 0.51 ENST00000302177.2
FOXA3
forkhead box A3
chr10_+_23983671 0.51 ENST00000376462.1
KIAA1217
KIAA1217
chr6_-_46459675 0.51 ENST00000306764.7
RCAN2
regulator of calcineurin 2
chr17_-_7518145 0.51 ENST00000250113.7
ENST00000571597.1
FXR2
fragile X mental retardation, autosomal homolog 2
chrX_+_131157322 0.50 ENST00000481105.1
ENST00000354719.6
ENST00000394335.2
MST4
Serine/threonine-protein kinase MST4
chr11_-_65686496 0.50 ENST00000449692.3
C11orf68
chromosome 11 open reading frame 68
chr11_-_65686586 0.50 ENST00000438576.2
C11orf68
chromosome 11 open reading frame 68
chr11_-_615942 0.50 ENST00000397562.3
ENST00000330243.5
ENST00000397570.1
ENST00000397574.2
IRF7
interferon regulatory factor 7
chr10_+_98592674 0.50 ENST00000356016.3
ENST00000371097.4
LCOR
ligand dependent nuclear receptor corepressor
chr16_+_31044812 0.49 ENST00000313843.3
STX4
syntaxin 4
chr19_-_19843900 0.48 ENST00000344099.3
ZNF14
zinc finger protein 14
chr2_-_135476552 0.48 ENST00000281924.6
TMEM163
transmembrane protein 163
chr12_-_57504069 0.48 ENST00000543873.2
ENST00000554663.1
ENST00000557635.1
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr17_+_54671047 0.48 ENST00000332822.4
NOG
noggin
chr11_+_109964087 0.48 ENST00000278590.3
ZC3H12C
zinc finger CCCH-type containing 12C
chr20_+_61287711 0.48 ENST00000370507.1
SLCO4A1
solute carrier organic anion transporter family, member 4A1
chr1_+_101361626 0.48 ENST00000370112.4
SLC30A7
solute carrier family 30 (zinc transporter), member 7
chr17_-_49198216 0.47 ENST00000262013.7
ENST00000357122.4
SPAG9
sperm associated antigen 9
chrX_+_45364633 0.47 ENST00000435394.1
ENST00000609127.1
RP11-245M24.1
RP11-245M24.1
chr1_-_156722015 0.47 ENST00000368209.5
HDGF
hepatoma-derived growth factor
chr17_-_1395954 0.47 ENST00000359786.5
MYO1C
myosin IC
chr12_-_1703331 0.47 ENST00000339235.3
FBXL14
F-box and leucine-rich repeat protein 14
chr17_-_28257080 0.47 ENST00000579954.1
ENST00000540801.1
ENST00000269033.3
ENST00000590153.1
ENST00000582084.1
SSH2
slingshot protein phosphatase 2
chr1_-_156721389 0.46 ENST00000537739.1
HDGF
hepatoma-derived growth factor
chr11_+_111411384 0.46 ENST00000375615.3
ENST00000525126.1
ENST00000436913.2
ENST00000533265.1
LAYN
layilin
chr1_+_184356188 0.46 ENST00000235307.6
C1orf21
chromosome 1 open reading frame 21
chr12_+_122242597 0.46 ENST00000267197.5
SETD1B
SET domain containing 1B
chr18_-_24128496 0.45 ENST00000417602.1
KCTD1
potassium channel tetramerization domain containing 1
chr5_+_67511524 0.45 ENST00000521381.1
ENST00000521657.1
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chrX_+_136648297 0.45 ENST00000287538.5
ZIC3
Zic family member 3
chr9_+_135906375 0.45 ENST00000372099.6
ENST00000372095.5
ENST00000372108.5
ENST00000342018.8
ENST00000439697.1
GTF3C5
general transcription factor IIIC, polypeptide 5, 63kDa
chr19_-_51529849 0.45 ENST00000600362.1
ENST00000453757.3
ENST00000601671.1
KLK11
kallikrein-related peptidase 11
chr1_+_155023757 0.44 ENST00000356955.2
ENST00000449910.2
ENST00000359280.4
ENST00000360674.4
ENST00000368412.3
ENST00000355956.2
ENST00000368410.2
ENST00000271836.6
ENST00000368413.1
ENST00000531455.1
ENST00000447332.3
ADAM15
ADAM metallopeptidase domain 15
chr3_-_178790057 0.44 ENST00000311417.2
ZMAT3
zinc finger, matrin-type 3
chr10_-_47173994 0.44 ENST00000414655.2
ENST00000545298.1
ENST00000359178.4
ENST00000358140.4
ENST00000503031.1
ANXA8L1
LINC00842
annexin A8-like 1
long intergenic non-protein coding RNA 842
chr2_-_27603582 0.44 ENST00000323703.6
ENST00000436006.1
ZNF513
zinc finger protein 513
chr1_+_16010779 0.44 ENST00000375799.3
ENST00000375793.2
PLEKHM2
pleckstrin homology domain containing, family M (with RUN domain) member 2
chr12_-_89919220 0.44 ENST00000549035.1
ENST00000393179.4
POC1B
POC1 centriolar protein B
chr10_+_103825080 0.44 ENST00000299238.5
HPS6
Hermansky-Pudlak syndrome 6
chr17_+_4487816 0.43 ENST00000389313.4
SMTNL2
smoothelin-like 2
chr19_+_17830051 0.43 ENST00000594625.1
ENST00000324096.4
ENST00000600186.1
ENST00000597735.1
MAP1S
microtubule-associated protein 1S
chr1_-_45288932 0.43 ENST00000438067.1
PTCH2
patched 2
chr5_+_112074029 0.43 ENST00000512211.2
APC
adenomatous polyposis coli
chr10_-_25012115 0.43 ENST00000446003.1
ARHGAP21
Rho GTPase activating protein 21
chr14_+_33408449 0.43 ENST00000346562.2
ENST00000341321.4
ENST00000548645.1
ENST00000356141.4
ENST00000357798.5
NPAS3
neuronal PAS domain protein 3
chr12_-_52887034 0.43 ENST00000330722.6
KRT6A
keratin 6A
chr3_+_19189946 0.43 ENST00000328405.2
KCNH8
potassium voltage-gated channel, subfamily H (eag-related), member 8
chr22_+_38004473 0.43 ENST00000414350.3
ENST00000343632.4
GGA1
golgi-associated, gamma adaptin ear containing, ARF binding protein 1
chr20_-_44539538 0.42 ENST00000372420.1
PLTP
phospholipid transfer protein
chr19_+_42746927 0.42 ENST00000378108.1
AC006486.1
AC006486.1
chr22_-_30970560 0.42 ENST00000402369.1
ENST00000406361.1
GAL3ST1
galactose-3-O-sulfotransferase 1
chr16_-_81110683 0.42 ENST00000565253.1
ENST00000378611.4
ENST00000299578.5
C16orf46
chromosome 16 open reading frame 46
chr15_+_71185148 0.42 ENST00000443425.2
ENST00000560755.1
LRRC49
leucine rich repeat containing 49
chr2_+_27346666 0.41 ENST00000316470.4
ENST00000416071.1
ABHD1
abhydrolase domain containing 1
chr12_+_122241928 0.41 ENST00000604567.1
ENST00000542440.1
SETD1B
SET domain containing 1B
chr19_+_54058073 0.41 ENST00000505949.1
ENST00000513265.1
ZNF331
zinc finger protein 331
chr22_-_38240412 0.41 ENST00000215941.4
ANKRD54
ankyrin repeat domain 54
chr13_+_49794474 0.41 ENST00000218721.1
ENST00000398307.1
MLNR
motilin receptor
chr7_+_75028199 0.41 ENST00000437796.1
TRIM73
tripartite motif containing 73
chr12_-_89919765 0.41 ENST00000541909.1
ENST00000313546.3
POC1B
POC1 centriolar protein B
chr6_-_119399895 0.41 ENST00000338891.7
FAM184A
family with sequence similarity 184, member A
chr7_+_26191809 0.41 ENST00000056233.3
NFE2L3
nuclear factor, erythroid 2-like 3
chr7_+_97736197 0.41 ENST00000297293.5
LMTK2
lemur tyrosine kinase 2
chr19_+_4343691 0.41 ENST00000597036.1
MPND
MPN domain containing
chr19_+_59055814 0.41 ENST00000594806.1
ENST00000253024.5
ENST00000341753.6
TRIM28
tripartite motif containing 28
chr4_-_109090106 0.40 ENST00000379951.2
LEF1
lymphoid enhancer-binding factor 1
chr1_+_11866270 0.40 ENST00000376497.3
ENST00000376487.3
ENST00000376496.3
CLCN6
chloride channel, voltage-sensitive 6
chr22_-_47134077 0.40 ENST00000541677.1
ENST00000216264.8
CERK
ceramide kinase
chr9_-_133814455 0.40 ENST00000448616.1
FIBCD1
fibrinogen C domain containing 1
chr16_+_50775948 0.40 ENST00000569681.1
ENST00000569418.1
ENST00000540145.1
CYLD
cylindromatosis (turban tumor syndrome)
chr16_+_56716336 0.39 ENST00000394485.4
ENST00000562939.1
MT1X
metallothionein 1X
chr5_+_169931249 0.39 ENST00000520740.1
KCNIP1
Kv channel interacting protein 1
chr6_-_134861089 0.39 ENST00000606039.1
RP11-557H15.4
RP11-557H15.4
chr17_-_26684473 0.39 ENST00000540200.1
POLDIP2
polymerase (DNA-directed), delta interacting protein 2
chr11_-_7818520 0.38 ENST00000329434.2
OR5P2
olfactory receptor, family 5, subfamily P, member 2
chrX_+_30671476 0.38 ENST00000378946.3
ENST00000378943.3
ENST00000378945.3
ENST00000427190.1
ENST00000378941.3
GK
glycerol kinase
chr5_+_149546334 0.38 ENST00000231656.8
CDX1
caudal type homeobox 1
chr5_-_139283982 0.38 ENST00000340391.3
NRG2
neuregulin 2
chr3_+_128720424 0.38 ENST00000480450.1
ENST00000436022.2
EFCC1
EF-hand and coiled-coil domain containing 1
chr9_+_140149625 0.38 ENST00000343053.4
NELFB
negative elongation factor complex member B
chr4_+_25235597 0.38 ENST00000264864.6
PI4K2B
phosphatidylinositol 4-kinase type 2 beta
chr6_-_114664180 0.38 ENST00000312719.5
HS3ST5
heparan sulfate (glucosamine) 3-O-sulfotransferase 5
chr19_+_57999101 0.37 ENST00000347466.6
ENST00000523138.1
ENST00000415379.2
ENST00000521754.1
ENST00000221735.7
ENST00000518999.1
ENST00000521137.1
ZNF419
zinc finger protein 419
chr1_-_26633067 0.37 ENST00000421827.2
ENST00000374215.1
ENST00000374223.1
ENST00000357089.4
ENST00000535108.1
ENST00000314675.7
ENST00000436301.2
ENST00000423664.1
ENST00000374221.3
UBXN11
UBX domain protein 11
chr1_-_153538292 0.37 ENST00000497140.1
ENST00000368708.3
S100A2
S100 calcium binding protein A2
chr3_+_6902794 0.37 ENST00000357716.4
ENST00000486284.1
ENST00000389336.4
ENST00000403881.1
ENST00000402647.2
GRM7
glutamate receptor, metabotropic 7
chr11_+_63870660 0.37 ENST00000246841.3
FLRT1
fibronectin leucine rich transmembrane protein 1
chr2_-_224702257 0.37 ENST00000409375.1
AP1S3
adaptor-related protein complex 1, sigma 3 subunit
chr19_+_4304585 0.37 ENST00000221856.6
FSD1
fibronectin type III and SPRY domain containing 1
chr5_+_178368186 0.37 ENST00000320129.3
ENST00000519564.1
ZNF454
zinc finger protein 454
chr7_-_128695147 0.36 ENST00000482320.1
ENST00000393245.1
ENST00000471234.1
TNPO3
transportin 3
chr7_-_100823496 0.36 ENST00000455377.1
ENST00000443096.1
ENST00000300303.2
NAT16
N-acetyltransferase 16 (GCN5-related, putative)
chr5_-_148033693 0.36 ENST00000377888.3
ENST00000360693.3
HTR4
5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
chr10_+_57358750 0.36 ENST00000512524.2
MTRNR2L5
MT-RNR2-like 5
chr9_+_135906076 0.36 ENST00000372097.5
ENST00000440319.1
GTF3C5
general transcription factor IIIC, polypeptide 5, 63kDa
chr1_-_115053781 0.36 ENST00000358465.2
ENST00000369543.2
TRIM33
tripartite motif containing 33
chr11_+_5372738 0.36 ENST00000380219.1
OR51B6
olfactory receptor, family 51, subfamily B, member 6
chr11_+_48002076 0.36 ENST00000418331.2
ENST00000440289.2
PTPRJ
protein tyrosine phosphatase, receptor type, J
chr2_+_202937972 0.35 ENST00000541917.1
ENST00000295844.3
AC079354.1
uncharacterized protein KIAA2012
chr20_+_61448376 0.35 ENST00000343916.3
COL9A3
collagen, type IX, alpha 3
chr1_-_153538011 0.35 ENST00000368707.4
S100A2
S100 calcium binding protein A2
chr5_+_78985673 0.35 ENST00000446378.2
CMYA5
cardiomyopathy associated 5
chr12_+_113659234 0.35 ENST00000551096.1
ENST00000551099.1
ENST00000335509.6
ENST00000552897.1
ENST00000550785.1
ENST00000549279.1
TPCN1
two pore segment channel 1
chr17_+_77893135 0.35 ENST00000574526.1
ENST00000572353.1
RP11-353N14.4
RP11-353N14.4
chr8_+_98656336 0.34 ENST00000336273.3
MTDH
metadherin
chr8_-_144691718 0.34 ENST00000377579.3
ENST00000433751.1
ENST00000220966.6
PYCRL
pyrroline-5-carboxylate reductase-like
chr1_-_156023580 0.34 ENST00000368309.3
UBQLN4
ubiquilin 4
chr11_+_2466218 0.34 ENST00000155840.5
KCNQ1
potassium voltage-gated channel, KQT-like subfamily, member 1
chr7_-_98741642 0.34 ENST00000361368.2
SMURF1
SMAD specific E3 ubiquitin protein ligase 1
chr19_+_57999079 0.34 ENST00000426954.2
ENST00000354197.4
ENST00000523882.1
ENST00000520540.1
ENST00000519310.1
ENST00000442920.2
ENST00000523312.1
ENST00000424930.2
ZNF419
zinc finger protein 419
chr12_+_22199108 0.34 ENST00000229329.2
CMAS
cytidine monophosphate N-acetylneuraminic acid synthetase
chr11_+_65686802 0.34 ENST00000376991.2
DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr12_-_122241812 0.34 ENST00000538335.1
AC084018.1
AC084018.1
chr19_-_55770311 0.34 ENST00000412770.2
PPP6R1
protein phosphatase 6, regulatory subunit 1
chr6_+_87865262 0.34 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
ZNF292
zinc finger protein 292
chr17_-_11900689 0.34 ENST00000322748.3
ENST00000454073.3
ENST00000580903.1
ENST00000580306.2
ZNF18
zinc finger protein 18
chr4_-_109089573 0.34 ENST00000265165.1
LEF1
lymphoid enhancer-binding factor 1
chr19_+_2164126 0.34 ENST00000398665.3
DOT1L
DOT1-like histone H3K79 methyltransferase
chrX_-_31090152 0.34 ENST00000359202.3
FTHL17
ferritin, heavy polypeptide-like 17
chr1_+_229385383 0.33 ENST00000323223.2
TMEM78
transmembrane protein 78
chr1_+_44444865 0.33 ENST00000372324.1
B4GALT2
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr1_-_204654481 0.33 ENST00000367176.3
LRRN2
leucine rich repeat neuronal 2
chr12_+_132628963 0.33 ENST00000330579.1
NOC4L
nucleolar complex associated 4 homolog (S. cerevisiae)
chr2_-_27357479 0.33 ENST00000406567.3
ENST00000260643.2
PREB
prolactin regulatory element binding
chr5_-_9546180 0.33 ENST00000382496.5
SEMA5A
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr10_+_72972281 0.33 ENST00000335350.6
UNC5B
unc-5 homolog B (C. elegans)
chr1_-_235667716 0.33 ENST00000313984.3
ENST00000366600.3
B3GALNT2
beta-1,3-N-acetylgalactosaminyltransferase 2
chr2_-_55276320 0.33 ENST00000357376.3
RTN4
reticulon 4
chr19_+_10982336 0.33 ENST00000344150.4
CARM1
coactivator-associated arginine methyltransferase 1
chr6_-_30658745 0.33 ENST00000376420.5
ENST00000376421.5
NRM
nurim (nuclear envelope membrane protein)
chr5_-_72744336 0.32 ENST00000499003.3
FOXD1
forkhead box D1
chr21_-_10990830 0.32 ENST00000361285.4
ENST00000342420.5
ENST00000328758.5
TPTE
transmembrane phosphatase with tensin homology

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:1990108 protein linear deubiquitination(GO:1990108)
0.3 0.9 GO:0071284 cellular response to lead ion(GO:0071284) positive regulation of bicellular tight junction assembly(GO:1903348)
0.3 1.4 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.3 0.8 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
0.3 0.8 GO:0070898 RNA polymerase III transcriptional preinitiation complex assembly(GO:0070898)
0.2 1.8 GO:0010587 miRNA catabolic process(GO:0010587)
0.2 0.7 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.2 0.6 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.2 0.6 GO:1902534 single-organism membrane invagination(GO:1902534)
0.2 1.9 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.2 0.6 GO:0034970 histone H3-R2 methylation(GO:0034970)
0.2 1.3 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.2 0.8 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.2 0.5 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.2 0.8 GO:0019230 proprioception(GO:0019230)
0.1 0.9 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.1 0.7 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.1 0.4 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.1 0.5 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.1 0.1 GO:0061317 canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317)
0.1 1.2 GO:0006477 protein sulfation(GO:0006477)
0.1 0.6 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.1 0.5 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.1 1.2 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.1 0.6 GO:2001074 regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076)
0.1 0.7 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 0.3 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.1 0.3 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.1 1.1 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.1 0.4 GO:0051710 cytolysis by symbiont of host cells(GO:0001897) regulation of cytolysis in other organism(GO:0051710)
0.1 0.7 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 0.4 GO:0042360 vitamin E metabolic process(GO:0042360)
0.1 1.1 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 0.4 GO:1901536 negative regulation of DNA demethylation(GO:1901536) regulation of genetic imprinting(GO:2000653)
0.1 0.3 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.1 0.5 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.1 1.2 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1 0.3 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.1 0.1 GO:0001743 optic placode formation(GO:0001743) optic placode formation involved in camera-type eye formation(GO:0046619)
0.1 0.2 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.1 0.5 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.1 0.3 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.1 0.8 GO:0001714 endodermal cell fate specification(GO:0001714)
0.1 0.2 GO:0006533 fumarate metabolic process(GO:0006106) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533)
0.1 0.3 GO:0072268 pattern specification involved in metanephros development(GO:0072268)
0.1 0.9 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.6 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.1 0.5 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.6 GO:0007506 gonadal mesoderm development(GO:0007506)
0.1 0.2 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.1 0.4 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.1 0.2 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.1 0.3 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.1 0.5 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.1 0.3 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 1.3 GO:0035641 locomotory exploration behavior(GO:0035641)
0.1 0.2 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 0.7 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1 0.3 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.1 0.2 GO:0018002 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.1 0.2 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.1 0.2 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 0.2 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.1 0.5 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.1 0.6 GO:0051660 establishment of centrosome localization(GO:0051660)
0.1 0.2 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.1 0.2 GO:0044691 tooth eruption(GO:0044691)
0.1 0.6 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.1 0.3 GO:0035900 response to isolation stress(GO:0035900)
0.1 0.4 GO:0009957 epidermal cell fate specification(GO:0009957)
0.1 0.6 GO:0042428 serotonin metabolic process(GO:0042428)
0.1 0.4 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.1 0.2 GO:0014806 heme oxidation(GO:0006788) smooth muscle hyperplasia(GO:0014806) negative regulation of mast cell cytokine production(GO:0032764)
0.1 0.1 GO:0071109 superior temporal gyrus development(GO:0071109)
0.1 0.2 GO:0099553 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.1 0.2 GO:0046833 positive regulation of nucleobase-containing compound transport(GO:0032241) positive regulation of RNA export from nucleus(GO:0046833)
0.0 0.4 GO:0036018 cellular response to erythropoietin(GO:0036018)
0.0 0.2 GO:0099550 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signalling, modulating synaptic transmission(GO:0099550) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.0 1.0 GO:0021681 cerebellar granular layer development(GO:0021681)
0.0 0.2 GO:0042631 cellular response to water deprivation(GO:0042631)
0.0 0.3 GO:0042713 sperm ejaculation(GO:0042713)
0.0 0.6 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.1 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.0 0.6 GO:0015074 DNA integration(GO:0015074)
0.0 0.4 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:2001037 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.0 0.5 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.7 GO:0001553 luteinization(GO:0001553)
0.0 0.4 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 0.2 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.4 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.2 GO:1904636 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.0 0.1 GO:0007412 axon target recognition(GO:0007412)
0.0 0.1 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.0 0.3 GO:0097623 potassium ion export across plasma membrane(GO:0097623)
0.0 0.1 GO:0048880 sensory system development(GO:0048880)
0.0 0.1 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.0 0.3 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0 0.3 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.2 GO:2000020 positive regulation of meiosis I(GO:0060903) positive regulation of male gonad development(GO:2000020)
0.0 0.3 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.2 GO:0003164 His-Purkinje system development(GO:0003164)
0.0 0.2 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 0.4 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 0.2 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.3 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.0 GO:0032900 negative regulation of neurotrophin production(GO:0032900)
0.0 0.4 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.3 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.9 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.2 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 1.0 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.9 GO:1900115 extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.1 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0 0.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.5 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.2 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.4 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.0 0.2 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.3 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.4 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.7 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.2 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.0 0.3 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.5 GO:0032785 negative regulation of DNA-templated transcription, elongation(GO:0032785)
0.0 0.3 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.1 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.1 GO:0036022 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.0 0.5 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.1 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.0 0.1 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.2 GO:1990822 basic amino acid transmembrane transport(GO:1990822)
0.0 0.2 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.6 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.2 GO:1903412 response to bile acid(GO:1903412)
0.0 0.9 GO:0003016 respiratory system process(GO:0003016)
0.0 0.2 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.2 GO:0070535 negative regulation of histone ubiquitination(GO:0033183) histone H2A K63-linked ubiquitination(GO:0070535) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.3 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.0 0.1 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.1 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.0 0.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.5 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.0 0.4 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.0 0.2 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.1 GO:1904526 regulation of microtubule binding(GO:1904526)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 1.6 GO:0021762 substantia nigra development(GO:0021762)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.4 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.1 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.6 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.2 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.4 GO:1900103 positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.0 0.2 GO:0003228 atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.0 0.1 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.0 0.3 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.5 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.3 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 0.2 GO:0021978 telencephalon regionalization(GO:0021978)
0.0 0.3 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.5 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.0 GO:0035989 tendon development(GO:0035989)
0.0 0.3 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.4 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.2 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.3 GO:0006702 androgen biosynthetic process(GO:0006702)
0.0 1.6 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0 0.1 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0 0.3 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.1 GO:0045113 regulation of integrin biosynthetic process(GO:0045113)
0.0 0.7 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.0 0.1 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.0 0.2 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.0 0.3 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.1 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.3 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.3 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.0 GO:0009996 negative regulation of cell fate specification(GO:0009996)
0.0 0.1 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.1 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:1904693 midbrain morphogenesis(GO:1904693)
0.0 0.8 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.8 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-independent nucleosome organization(GO:0034724)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.2 GO:0021756 striatum development(GO:0021756)
0.0 0.2 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.3 GO:0032098 regulation of appetite(GO:0032098)
0.0 0.1 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.0 0.1 GO:1900756 protein processing in phagocytic vesicle(GO:1900756) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923)
0.0 0.1 GO:0015820 leucine transport(GO:0015820)
0.0 0.3 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.0 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.0 0.1 GO:0090487 toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487)
0.0 0.5 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.3 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 1.0 GO:0001895 retina homeostasis(GO:0001895)
0.0 0.2 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.3 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.4 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.3 GO:0051642 centrosome localization(GO:0051642)
0.0 0.0 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.8 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.6 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.1 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.0 0.3 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.2 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.6 GO:0031663 lipopolysaccharide-mediated signaling pathway(GO:0031663)
0.0 0.0 GO:0070384 Harderian gland development(GO:0070384)
0.0 0.4 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.5 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.2 GO:0030299 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0 0.1 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.2 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.0 1.0 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.0 0.1 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.2 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.6 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.0 0.2 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.3 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 0.4 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.1 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 0.6 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 0.5 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 0.5 GO:0045160 myosin I complex(GO:0045160)
0.1 0.4 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1 0.3 GO:0030689 Noc complex(GO:0030689)
0.1 0.8 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 0.3 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.1 1.1 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.4 GO:0032021 NELF complex(GO:0032021)
0.1 0.4 GO:0032279 asymmetric synapse(GO:0032279)
0.1 0.7 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 1.0 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 0.6 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.3 GO:0005594 collagen type IX trimer(GO:0005594)
0.1 0.2 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.3 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.6 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.1 0.5 GO:0005638 lamin filament(GO:0005638)
0.0 0.2 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.2 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.1 GO:0018444 translation release factor complex(GO:0018444)
0.0 1.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.5 GO:0030897 HOPS complex(GO:0030897)
0.0 1.0 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 2.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.9 GO:0043194 axon initial segment(GO:0043194)
0.0 0.1 GO:0032044 DSIF complex(GO:0032044)
0.0 0.3 GO:0070695 FHF complex(GO:0070695)
0.0 0.6 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.3 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.2 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 0.1 GO:0000814 ESCRT II complex(GO:0000814)
0.0 0.6 GO:0032059 bleb(GO:0032059)
0.0 0.7 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 1.7 GO:0097542 ciliary tip(GO:0097542)
0.0 0.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.6 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.3 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.3 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 2.2 GO:0031594 neuromuscular junction(GO:0031594)
0.0 1.0 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.9 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.2 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.4 GO:0000800 lateral element(GO:0000800)
0.0 0.2 GO:0061202 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 0.4 GO:0036038 MKS complex(GO:0036038)
0.0 0.1 GO:0044753 amphisome(GO:0044753)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 1.3 GO:0002102 podosome(GO:0002102)
0.0 0.6 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.4 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.5 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 1.1 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.1 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.3 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.3 GO:0034706 sodium channel complex(GO:0034706)
0.0 0.4 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.1 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0044308 axonal spine(GO:0044308)
0.0 0.0 GO:1990031 pinceau fiber(GO:1990031)
0.0 0.4 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 2.4 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.4 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 2.0 GO:0001650 fibrillar center(GO:0001650)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.6 GO:0030131 clathrin adaptor complex(GO:0030131)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0042007 interleukin-18 binding(GO:0042007)
0.3 1.2 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.3 0.8 GO:0001034 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003) RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.2 0.2 GO:0032427 GBD domain binding(GO:0032427)
0.2 0.7 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.2 0.5 GO:0005124 scavenger receptor binding(GO:0005124)
0.2 2.0 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 1.9 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 0.5 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1 1.0 GO:0070097 delta-catenin binding(GO:0070097)
0.1 1.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 0.4 GO:0038025 reelin receptor activity(GO:0038025)
0.1 0.5 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.1 0.6 GO:0042835 BRE binding(GO:0042835)
0.1 0.7 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.1 0.7 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1 1.5 GO:0031996 thioesterase binding(GO:0031996)
0.1 0.3 GO:0004370 glycerol kinase activity(GO:0004370)
0.1 0.8 GO:0008158 hedgehog receptor activity(GO:0008158)
0.1 0.3 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.1 0.3 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 0.3 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 0.6 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.5 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.3 GO:0004461 lactose synthase activity(GO:0004461)
0.1 0.2 GO:0070546 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137) L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1 1.6 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 0.6 GO:0046979 TAP2 binding(GO:0046979)
0.1 1.2 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 0.3 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.1 0.2 GO:0035034 histone acetyltransferase regulator activity(GO:0035034)
0.1 0.4 GO:0070905 serine binding(GO:0070905)
0.1 0.2 GO:0036317 tyrosyl-RNA phosphodiesterase activity(GO:0036317) 5'-tyrosyl-DNA phosphodiesterase activity(GO:0070260)
0.1 0.5 GO:0070569 uridylyltransferase activity(GO:0070569)
0.1 0.4 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.1 1.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 0.3 GO:0030395 lactose binding(GO:0030395)
0.1 0.3 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.1 0.3 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.4 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.1 0.9 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.2 GO:0016855 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.1 0.2 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.1 0.8 GO:0005131 growth hormone receptor binding(GO:0005131)
0.1 1.1 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 0.3 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 0.2 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1 0.4 GO:0001727 lipid kinase activity(GO:0001727)
0.1 1.1 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 0.3 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.1 0.5 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.4 GO:0043559 insulin binding(GO:0043559)
0.1 1.0 GO:0048185 activin binding(GO:0048185)
0.1 0.2 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.1 0.3 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 0.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 1.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.5 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.1 0.6 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.1 0.4 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.5 GO:0031419 cobalamin binding(GO:0031419)
0.0 1.1 GO:0008483 transaminase activity(GO:0008483)
0.0 0.4 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.6 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.6 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.8 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.2 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.3 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.1 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.0 0.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.3 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.3 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.2 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.8 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 0.8 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.6 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.2 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.0 0.2 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.6 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.2 GO:0070728 leucine binding(GO:0070728)
0.0 0.3 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.6 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.1 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.3 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 0.2 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.9 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0004939 beta-adrenergic receptor activity(GO:0004939) norepinephrine binding(GO:0051380)
0.0 0.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.4 GO:0008061 chitin binding(GO:0008061)
0.0 0.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.6 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 1.5 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.9 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.3 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.2 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.1 GO:0050610 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.0 0.1 GO:0034584 piRNA binding(GO:0034584)
0.0 0.2 GO:0005497 androgen binding(GO:0005497)
0.0 0.1 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.0 0.1 GO:0045118 azole transporter activity(GO:0045118)
0.0 0.4 GO:0005549 odorant binding(GO:0005549)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.1 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 0.1 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.5 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.2 GO:0005167 neurotrophin TRK receptor binding(GO:0005167)
0.0 1.9 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.5 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.1 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.2 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.3 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.8 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.6 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.5 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.4 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.7 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.0 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.0 0.4 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.3 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.2 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.5 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.2 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.2 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.4 GO:0030742 GTP-dependent protein binding(GO:0030742)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 1.9 PID CD40 PATHWAY CD40/CD40L signaling
0.0 1.8 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.4 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 1.5 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.9 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 1.0 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.5 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.5 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.9 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.9 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.1 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.4 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.4 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.0 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.8 PID ATM PATHWAY ATM pathway
0.0 0.3 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.1 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.1 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.1 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.5 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway
0.0 0.9 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.5 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.6 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.4 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.4 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.1 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 1.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 1.9 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 1.1 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 1.1 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.4 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 1.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.8 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.4 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 1.1 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.7 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.8 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.5 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.8 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.6 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.6 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.5 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.6 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.9 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.6 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.8 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.4 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.4 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.6 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.9 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.4 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.8 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.8 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.3 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.2 REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.0 1.3 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.9 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 1.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.2 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.9 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.4 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 1.0 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.4 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.4 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha