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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for ZBTB7A_ZBTB7C

Z-value: 0.70

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Transcription factors associated with ZBTB7A_ZBTB7C

Gene Symbol Gene ID Gene Info
ZBTB7A
ENSG00000178951.4 zinc finger and BTB domain containing 7A
ZBTB7C
ENSG00000184828.5 zinc finger and BTB domain containing 7C

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZBTB7Chg19_v2_chr18_-_45663666_45663732,
hg19_v2_chr18_-_45935663_45935793		-0.563.5e-03Click!
ZBTB7Ahg19_v2_chr19_-_4065730_4065909-0.349.8e-02Click!

Activity profile of ZBTB7A_ZBTB7C motif

Sorted Z-values of ZBTB7A_ZBTB7C motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_17354587 2.27 ENST00000494857.1
ENST00000522656.1
SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr8_+_17354617 2.22 ENST00000470360.1
SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr1_+_169075554 1.19 ENST00000367815.4
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr1_-_156721389 0.88 ENST00000537739.1
HDGF
hepatoma-derived growth factor
chr1_-_156721502 0.84 ENST00000357325.5
HDGF
hepatoma-derived growth factor
chr10_-_101380121 0.83 ENST00000370495.4
SLC25A28
solute carrier family 25 (mitochondrial iron transporter), member 28
chr4_-_47916543 0.75 ENST00000507489.1
NFXL1
nuclear transcription factor, X-box binding-like 1
chr1_-_38273840 0.70 ENST00000373044.2
YRDC
yrdC N(6)-threonylcarbamoyltransferase domain containing
chr17_+_40834580 0.69 ENST00000264638.4
CNTNAP1
contactin associated protein 1
chr19_+_10197463 0.69 ENST00000590378.1
ENST00000397881.3
C19orf66
chromosome 19 open reading frame 66
chr2_-_235405168 0.64 ENST00000339728.3
ARL4C
ADP-ribosylation factor-like 4C
chr14_+_59655369 0.64 ENST00000360909.3
ENST00000351081.1
ENST00000556135.1
DAAM1
dishevelled associated activator of morphogenesis 1
chr11_-_117747434 0.59 ENST00000529335.2
ENST00000530956.1
ENST00000260282.4
FXYD6
FXYD domain containing ion transport regulator 6
chr11_-_117747607 0.58 ENST00000540359.1
ENST00000539526.1
FXYD6
FXYD domain containing ion transport regulator 6
chr10_+_101419187 0.52 ENST00000370489.4
ENTPD7
ectonucleoside triphosphate diphosphohydrolase 7
chrX_-_151143140 0.52 ENST00000393914.3
ENST00000370328.3
ENST00000370325.1
GABRE
gamma-aminobutyric acid (GABA) A receptor, epsilon
chr2_-_74692473 0.51 ENST00000535045.1
ENST00000409065.1
ENST00000414701.1
ENST00000448666.1
ENST00000233616.4
ENST00000452063.2
MOGS
mannosyl-oligosaccharide glucosidase
chr1_+_182992545 0.49 ENST00000258341.4
LAMC1
laminin, gamma 1 (formerly LAMB2)
chr4_+_74718906 0.48 ENST00000226524.3
PF4V1
platelet factor 4 variant 1
chr1_-_156722015 0.47 ENST00000368209.5
HDGF
hepatoma-derived growth factor
chr7_+_26191809 0.46 ENST00000056233.3
NFE2L3
nuclear factor, erythroid 2-like 3
chr15_-_62352659 0.46 ENST00000249837.3
VPS13C
vacuolar protein sorting 13 homolog C (S. cerevisiae)
chr6_+_64282447 0.44 ENST00000370650.2
ENST00000578299.1
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr10_-_105615164 0.42 ENST00000355946.2
ENST00000369774.4
SH3PXD2A
SH3 and PX domains 2A
chr9_+_140500087 0.41 ENST00000371421.4
ARRDC1
arrestin domain containing 1
chr17_-_1531635 0.41 ENST00000571650.1
SLC43A2
solute carrier family 43 (amino acid system L transporter), member 2
chr15_-_64126084 0.37 ENST00000560316.1
ENST00000443617.2
ENST00000560462.1
ENST00000558532.1
ENST00000561400.1
HERC1
HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
chr1_-_21616901 0.37 ENST00000436918.2
ENST00000374893.6
ECE1
endothelin converting enzyme 1
chr8_+_27629459 0.35 ENST00000523566.1
ESCO2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr14_+_29236269 0.34 ENST00000313071.4
FOXG1
forkhead box G1
chr6_-_82462425 0.34 ENST00000369754.3
ENST00000320172.6
ENST00000369756.3
FAM46A
family with sequence similarity 46, member A
chr1_-_111506562 0.34 ENST00000485275.2
ENST00000369763.4
LRIF1
ligand dependent nuclear receptor interacting factor 1
chr8_-_101963482 0.33 ENST00000419477.2
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr1_+_167691191 0.33 ENST00000392121.3
ENST00000474859.1
MPZL1
myelin protein zero-like 1
chr9_-_74525847 0.32 ENST00000377041.2
ABHD17B
abhydrolase domain containing 17B
chr1_+_167691185 0.32 ENST00000359523.2
MPZL1
myelin protein zero-like 1
chr6_-_46459675 0.32 ENST00000306764.7
RCAN2
regulator of calcineurin 2
chrX_+_153991025 0.32 ENST00000369550.5
DKC1
dyskeratosis congenita 1, dyskerin
chr4_-_146101304 0.32 ENST00000447906.2
OTUD4
OTU domain containing 4
chr7_+_77167343 0.30 ENST00000433369.2
ENST00000415482.2
PTPN12
protein tyrosine phosphatase, non-receptor type 12
chr17_+_79990058 0.30 ENST00000584341.1
RAC3
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr22_+_21369316 0.30 ENST00000413302.2
ENST00000402329.3
ENST00000336296.2
ENST00000401443.1
ENST00000443995.3
P2RX6
purinergic receptor P2X, ligand-gated ion channel, 6
chr9_+_132934835 0.30 ENST00000372398.3
NCS1
neuronal calcium sensor 1
chr1_+_15480197 0.29 ENST00000400796.3
ENST00000434578.2
ENST00000376008.2
TMEM51
transmembrane protein 51
chr17_+_79989937 0.27 ENST00000580965.1
RAC3
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr5_-_132113036 0.27 ENST00000378706.1
SEPT8
septin 8
chr12_-_49351148 0.27 ENST00000398092.4
ENST00000539611.1
RP11-302B13.5
ARF3
ADP-ribosylation factor 3
ADP-ribosylation factor 3
chr9_-_133814455 0.26 ENST00000448616.1
FIBCD1
fibrinogen C domain containing 1
chr12_-_56224546 0.25 ENST00000357606.3
ENST00000547445.1
DNAJC14
DnaJ (Hsp40) homolog, subfamily C, member 14
chr17_-_1532106 0.25 ENST00000301335.5
ENST00000382147.4
SLC43A2
solute carrier family 43 (amino acid system L transporter), member 2
chr4_-_7069760 0.25 ENST00000264954.4
GRPEL1
GrpE-like 1, mitochondrial (E. coli)
chr21_-_47648665 0.25 ENST00000450351.1
ENST00000522411.1
ENST00000356396.4
ENST00000397728.3
ENST00000457828.2
LSS
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
chr15_-_41408339 0.25 ENST00000401393.3
INO80
INO80 complex subunit
chr3_-_164914640 0.25 ENST00000241274.3
SLITRK3
SLIT and NTRK-like family, member 3
chr5_-_132113559 0.24 ENST00000448933.1
SEPT8
septin 8
chr8_+_145202939 0.24 ENST00000423230.2
ENST00000398656.4
MROH1
maestro heat-like repeat family member 1
chr5_-_2751762 0.24 ENST00000302057.5
ENST00000382611.6
IRX2
iroquois homeobox 2
chr6_-_33290580 0.24 ENST00000446511.1
ENST00000446403.1
ENST00000414083.2
ENST00000266000.6
ENST00000374542.5
DAXX
death-domain associated protein
chr5_-_138739739 0.24 ENST00000514983.1
ENST00000507779.2
ENST00000451821.2
ENST00000450845.2
ENST00000509959.1
ENST00000302091.5
SPATA24
spermatogenesis associated 24
chr1_+_38273818 0.24 ENST00000373042.4
C1orf122
chromosome 1 open reading frame 122
chr5_-_132112907 0.24 ENST00000458488.2
SEPT8
septin 8
chr12_-_42631529 0.24 ENST00000548917.1
YAF2
YY1 associated factor 2
chr1_+_38273988 0.23 ENST00000446260.2
C1orf122
chromosome 1 open reading frame 122
chr7_+_66093851 0.23 ENST00000275532.3
KCTD7
potassium channel tetramerization domain containing 7
chr5_-_132112921 0.22 ENST00000378721.4
ENST00000378701.1
SEPT8
septin 8
chr15_+_92396920 0.22 ENST00000318445.6
SLCO3A1
solute carrier organic anion transporter family, member 3A1
chr20_+_37590942 0.22 ENST00000373325.2
ENST00000252011.3
ENST00000373323.4
DHX35
DEAH (Asp-Glu-Ala-His) box polypeptide 35
chr2_+_48667983 0.21 ENST00000449090.2
PPP1R21
protein phosphatase 1, regulatory subunit 21
chr1_+_167905894 0.21 ENST00000367843.3
ENST00000432587.2
ENST00000312263.6
DCAF6
DDB1 and CUL4 associated factor 6
chr1_-_95007193 0.21 ENST00000370207.4
ENST00000334047.7
F3
coagulation factor III (thromboplastin, tissue factor)
chr19_+_40697514 0.21 ENST00000253055.3
MAP3K10
mitogen-activated protein kinase kinase kinase 10
chr12_+_22199108 0.21 ENST00000229329.2
CMAS
cytidine monophosphate N-acetylneuraminic acid synthetase
chr17_+_6926339 0.21 ENST00000293805.5
BCL6B
B-cell CLL/lymphoma 6, member B
chr6_+_30689401 0.21 ENST00000396389.1
ENST00000396384.1
TUBB
tubulin, beta class I
chr10_-_99094458 0.21 ENST00000371019.2
FRAT2
frequently rearranged in advanced T-cell lymphomas 2
chr12_+_107349497 0.21 ENST00000548125.1
ENST00000280756.4
C12orf23
chromosome 12 open reading frame 23
chr5_+_72861560 0.20 ENST00000296792.4
ENST00000509005.1
ENST00000543251.1
ENST00000508686.1
ENST00000508491.1
UTP15
UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae)
chr7_-_94285511 0.20 ENST00000265735.7
SGCE
sarcoglycan, epsilon
chr3_-_179754556 0.20 ENST00000263962.8
PEX5L
peroxisomal biogenesis factor 5-like
chr5_-_132113083 0.20 ENST00000296873.7
SEPT8
septin 8
chr1_-_92952433 0.20 ENST00000294702.5
GFI1
growth factor independent 1 transcription repressor
chr7_-_94285472 0.19 ENST00000437425.2
ENST00000447873.1
ENST00000415788.2
SGCE
sarcoglycan, epsilon
chr9_+_74764278 0.19 ENST00000238018.4
ENST00000376989.3
GDA
guanine deaminase
chr7_+_66093908 0.19 ENST00000443322.1
ENST00000449064.1
KCTD7
potassium channel tetramerization domain containing 7
chr15_-_41408409 0.19 ENST00000361937.3
INO80
INO80 complex subunit
chr19_+_49622646 0.18 ENST00000334186.4
PPFIA3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr16_-_49315731 0.18 ENST00000219197.6
CBLN1
cerebellin 1 precursor
chr19_+_45394477 0.18 ENST00000252487.5
ENST00000405636.2
ENST00000592434.1
ENST00000426677.2
ENST00000589649.1
TOMM40
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr9_-_96213828 0.18 ENST00000423591.1
FAM120AOS
family with sequence similarity 120A opposite strand
chr16_+_610407 0.18 ENST00000409413.3
C16orf11
chromosome 16 open reading frame 11
chr20_-_61557821 0.18 ENST00000354665.4
ENST00000370368.1
ENST00000395343.1
ENST00000395340.1
DIDO1
death inducer-obliterator 1
chr7_-_51384451 0.18 ENST00000441453.1
ENST00000265136.7
ENST00000395542.2
ENST00000395540.2
COBL
cordon-bleu WH2 repeat protein
chr5_+_76506706 0.17 ENST00000340978.3
ENST00000346042.3
ENST00000264917.5
ENST00000342343.4
ENST00000333194.4
PDE8B
phosphodiesterase 8B
chr8_-_140715294 0.17 ENST00000303015.1
ENST00000520439.1
KCNK9
potassium channel, subfamily K, member 9
chr3_-_136471204 0.17 ENST00000480733.1
ENST00000383202.2
ENST00000236698.5
ENST00000434713.2
STAG1
stromal antigen 1
chr2_+_149402553 0.17 ENST00000258484.6
ENST00000409654.1
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr8_+_22298578 0.17 ENST00000240139.5
ENST00000289963.8
ENST00000397775.3
PPP3CC
protein phosphatase 3, catalytic subunit, gamma isozyme
chr19_-_59070239 0.17 ENST00000595957.1
ENST00000253023.3
UBE2M
ubiquitin-conjugating enzyme E2M
chr13_+_110959598 0.17 ENST00000360467.5
COL4A2
collagen, type IV, alpha 2
chr14_-_71276211 0.17 ENST00000381250.4
ENST00000555993.2
MAP3K9
mitogen-activated protein kinase kinase kinase 9
chr9_+_109625378 0.17 ENST00000277225.5
ENST00000457913.1
ENST00000472574.1
ZNF462
zinc finger protein 462
chr5_-_114515734 0.16 ENST00000514154.1
ENST00000282369.3
TRIM36
tripartite motif containing 36
chr19_+_35634146 0.16 ENST00000586063.1
ENST00000270310.2
ENST00000588265.1
FXYD7
FXYD domain containing ion transport regulator 7
chr14_-_24584138 0.16 ENST00000558280.1
ENST00000561028.1
NRL
neural retina leucine zipper
chr17_-_30185971 0.16 ENST00000378634.2
COPRS
coordinator of PRMT5, differentiation stimulator
chr11_-_117747327 0.16 ENST00000584230.1
ENST00000527429.1
ENST00000584394.1
ENST00000532984.1
FXYD6
FXYD6-FXYD2
FXYD domain containing ion transport regulator 6
FXYD6-FXYD2 readthrough
chr9_+_74526384 0.15 ENST00000334731.2
ENST00000377031.3
C9orf85
chromosome 9 open reading frame 85
chr1_+_4714792 0.15 ENST00000378190.3
AJAP1
adherens junctions associated protein 1
chr6_-_109703600 0.15 ENST00000512821.1
CD164
CD164 molecule, sialomucin
chr20_-_17662705 0.15 ENST00000455029.2
RRBP1
ribosome binding protein 1
chr7_+_77167376 0.15 ENST00000435495.2
PTPN12
protein tyrosine phosphatase, non-receptor type 12
chr7_-_112430427 0.15 ENST00000449743.1
ENST00000441474.1
ENST00000454074.1
ENST00000447395.1
TMEM168
transmembrane protein 168
chr8_-_38853990 0.15 ENST00000456845.2
ENST00000397070.2
ENST00000517872.1
ENST00000412303.1
ENST00000456397.2
TM2D2
TM2 domain containing 2
chr20_+_36149602 0.15 ENST00000062104.2
ENST00000346199.2
NNAT
neuronatin
chr8_-_101964231 0.15 ENST00000521309.1
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr2_+_46769798 0.15 ENST00000238738.4
RHOQ
ras homolog family member Q
chr9_-_131790464 0.14 ENST00000417224.1
ENST00000416629.1
ENST00000372559.1
SH3GLB2
SH3-domain GRB2-like endophilin B2
chr8_-_134584152 0.14 ENST00000521180.1
ENST00000517668.1
ENST00000319914.5
ST3GAL1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr1_-_167905225 0.14 ENST00000367846.4
MPC2
mitochondrial pyruvate carrier 2
chr4_-_76598296 0.14 ENST00000395719.3
G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr14_+_29234870 0.14 ENST00000382535.3
FOXG1
forkhead box G1
chr5_-_139283982 0.14 ENST00000340391.3
NRG2
neuregulin 2
chr17_+_73201754 0.14 ENST00000583569.1
ENST00000245544.4
ENST00000579324.1
ENST00000541827.1
ENST00000579298.1
ENST00000447371.2
NUP85
nucleoporin 85kDa
chr12_-_52867569 0.14 ENST00000252250.6
KRT6C
keratin 6C
chr1_+_93811438 0.13 ENST00000370272.4
ENST00000370267.1
DR1
down-regulator of transcription 1, TBP-binding (negative cofactor 2)
chr8_-_101963677 0.13 ENST00000395956.3
ENST00000395953.2
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr17_-_42441204 0.13 ENST00000293443.7
FAM171A2
family with sequence similarity 171, member A2
chr16_+_215965 0.13 ENST00000356815.3
HBM
hemoglobin, mu
chr15_-_75743915 0.13 ENST00000394949.4
SIN3A
SIN3 transcription regulator family member A
chr19_-_12945362 0.13 ENST00000590404.1
ENST00000592204.1
RTBDN
retbindin
chr10_+_60145155 0.13 ENST00000373895.3
TFAM
transcription factor A, mitochondrial
chr5_+_140071011 0.13 ENST00000230771.3
ENST00000509299.1
ENST00000503873.1
ENST00000435019.2
ENST00000437649.2
ENST00000432671.2
HARS2
histidyl-tRNA synthetase 2, mitochondrial
chr19_-_49622348 0.13 ENST00000408991.2
C19orf73
chromosome 19 open reading frame 73
chr4_+_72053017 0.13 ENST00000351898.6
SLC4A4
solute carrier family 4 (sodium bicarbonate cotransporter), member 4
chr14_+_33408449 0.12 ENST00000346562.2
ENST00000341321.4
ENST00000548645.1
ENST00000356141.4
ENST00000357798.5
NPAS3
neuronal PAS domain protein 3
chr1_-_111217603 0.12 ENST00000369769.2
KCNA3
potassium voltage-gated channel, shaker-related subfamily, member 3
chr7_-_94285402 0.12 ENST00000428696.2
ENST00000445866.2
SGCE
sarcoglycan, epsilon
chr4_+_95373037 0.12 ENST00000359265.4
ENST00000437932.1
ENST00000380180.3
ENST00000318007.5
ENST00000450793.1
ENST00000538141.1
ENST00000317968.4
ENST00000512274.1
ENST00000503974.1
ENST00000504489.1
ENST00000542407.1
PDLIM5
PDZ and LIM domain 5
chr9_-_139094988 0.12 ENST00000371746.3
LHX3
LIM homeobox 3
chrX_+_133507389 0.12 ENST00000370800.4
PHF6
PHD finger protein 6
chr22_+_42229100 0.12 ENST00000361204.4
SREBF2
sterol regulatory element binding transcription factor 2
chr17_-_40428359 0.12 ENST00000293328.3
STAT5B
signal transducer and activator of transcription 5B
chr19_-_663277 0.12 ENST00000292363.5
RNF126
ring finger protein 126
chr2_+_242255297 0.12 ENST00000401990.1
ENST00000407971.1
ENST00000436795.1
ENST00000411484.1
ENST00000434955.1
ENST00000402092.2
ENST00000441533.1
ENST00000443492.1
ENST00000437066.1
ENST00000429791.1
SEPT2
septin 2
chr17_-_46799872 0.12 ENST00000290294.3
PRAC1
prostate cancer susceptibility candidate 1
chr1_-_167906277 0.12 ENST00000271373.4
MPC2
mitochondrial pyruvate carrier 2
chr6_+_30689350 0.12 ENST00000330914.3
TUBB
tubulin, beta class I
chr1_-_22469459 0.11 ENST00000290167.6
WNT4
wingless-type MMTV integration site family, member 4
chr12_-_107487604 0.11 ENST00000008527.5
CRY1
cryptochrome 1 (photolyase-like)
chr2_+_191513789 0.11 ENST00000409581.1
NAB1
NGFI-A binding protein 1 (EGR1 binding protein 1)
chr18_+_55102917 0.11 ENST00000491143.2
ONECUT2
one cut homeobox 2
chr15_+_92397051 0.11 ENST00000424469.2
SLCO3A1
solute carrier organic anion transporter family, member 3A1
chr15_-_62352570 0.11 ENST00000261517.5
ENST00000395896.4
ENST00000395898.3
VPS13C
vacuolar protein sorting 13 homolog C (S. cerevisiae)
chr1_+_45792541 0.10 ENST00000334815.3
HPDL
4-hydroxyphenylpyruvate dioxygenase-like
chr2_+_58655461 0.10 ENST00000429095.1
ENST00000429664.1
ENST00000452840.1
AC007092.1
long intergenic non-protein coding RNA 1122
chr17_+_29158962 0.10 ENST00000321990.4
ATAD5
ATPase family, AAA domain containing 5
chr12_-_56221330 0.10 ENST00000546837.1
RP11-762I7.5
Uncharacterized protein
chr8_+_75896731 0.10 ENST00000262207.4
CRISPLD1
cysteine-rich secretory protein LCCL domain containing 1
chr5_-_140070897 0.10 ENST00000448240.1
ENST00000438307.2
ENST00000415192.2
ENST00000457527.2
ENST00000307633.3
ENST00000507746.1
ENST00000431330.2
HARS
histidyl-tRNA synthetase
chr6_-_109703634 0.10 ENST00000324953.5
ENST00000310786.4
ENST00000275080.7
ENST00000413644.2
CD164
CD164 molecule, sialomucin
chr19_-_49222956 0.10 ENST00000599703.1
ENST00000318083.6
ENST00000419611.1
ENST00000377367.3
MAMSTR
MEF2 activating motif and SAP domain containing transcriptional regulator
chr4_-_105416039 0.10 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr11_-_1330834 0.10 ENST00000525159.1
ENST00000317204.6
ENST00000542915.1
ENST00000527938.1
ENST00000530541.1
ENST00000263646.7
TOLLIP
toll interacting protein
chr12_+_132312931 0.09 ENST00000360564.1
ENST00000545671.1
ENST00000545790.1
MMP17
matrix metallopeptidase 17 (membrane-inserted)
chr5_-_137878887 0.09 ENST00000507939.1
ENST00000572514.1
ENST00000499810.2
ENST00000360541.5
ETF1
eukaryotic translation termination factor 1
chr3_+_15468862 0.09 ENST00000396842.2
EAF1
ELL associated factor 1
chr9_+_135037334 0.09 ENST00000393229.3
ENST00000360670.3
ENST00000393228.4
ENST00000372179.3
NTNG2
netrin G2
chr1_+_162467595 0.09 ENST00000538489.1
ENST00000489294.1
UHMK1
U2AF homology motif (UHM) kinase 1
chr6_-_36953833 0.09 ENST00000538808.1
ENST00000460219.1
ENST00000373616.5
ENST00000373627.5
MTCH1
mitochondrial carrier 1
chr14_-_102771516 0.09 ENST00000524214.1
ENST00000193029.6
ENST00000361847.2
MOK
MOK protein kinase
chr1_-_84972248 0.09 ENST00000370645.4
ENST00000370641.3
GNG5
guanine nucleotide binding protein (G protein), gamma 5
chr17_-_58469687 0.09 ENST00000590133.1
USP32
ubiquitin specific peptidase 32
chr19_-_13044494 0.09 ENST00000593021.1
ENST00000587981.1
ENST00000423140.2
ENST00000314606.4
FARSA
phenylalanyl-tRNA synthetase, alpha subunit
chr2_+_242255275 0.09 ENST00000391971.2
SEPT2
septin 2
chr3_-_113415441 0.09 ENST00000491165.1
ENST00000316407.4
KIAA2018
KIAA2018
chr1_+_167906056 0.08 ENST00000367840.3
DCAF6
DDB1 and CUL4 associated factor 6
chr12_-_58240470 0.08 ENST00000548823.1
ENST00000398073.2
CTDSP2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr16_-_2059797 0.08 ENST00000563630.1
ZNF598
zinc finger protein 598
chr8_-_74884511 0.08 ENST00000518127.1
TCEB1
transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
chr1_+_89246647 0.08 ENST00000544045.1
PKN2
protein kinase N2
chr6_+_73331520 0.08 ENST00000342056.2
ENST00000355194.4
KCNQ5
potassium voltage-gated channel, KQT-like subfamily, member 5
chr8_-_74884482 0.08 ENST00000520242.1
ENST00000519082.1
TCEB1
transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
chr8_-_59572093 0.08 ENST00000427130.2
NSMAF
neutral sphingomyelinase (N-SMase) activation associated factor
chr17_-_40835076 0.08 ENST00000591765.1
CCR10
chemokine (C-C motif) receptor 10
chr11_-_64013663 0.08 ENST00000392210.2
PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr19_-_48673552 0.08 ENST00000536218.1
ENST00000596549.1
LIG1
ligase I, DNA, ATP-dependent
chr1_+_53098862 0.08 ENST00000517870.1
FAM159A
family with sequence similarity 159, member A
chrX_+_152783131 0.08 ENST00000349466.2
ENST00000370186.1
ATP2B3
ATPase, Ca++ transporting, plasma membrane 3
chr11_-_62752455 0.07 ENST00000360421.4
SLC22A6
solute carrier family 22 (organic anion transporter), member 6
chr11_-_62752162 0.07 ENST00000458333.2
ENST00000421062.2
SLC22A6
solute carrier family 22 (organic anion transporter), member 6
chr1_+_25664408 0.07 ENST00000374358.4
TMEM50A
transmembrane protein 50A
chr17_-_63556414 0.07 ENST00000585045.1
AXIN2
axin 2
chr6_+_126070726 0.07 ENST00000368364.3
HEY2
hes-related family bHLH transcription factor with YRPW motif 2
chr16_+_12995614 0.07 ENST00000423335.2
SHISA9
shisa family member 9
chr8_-_74884399 0.07 ENST00000520210.1
ENST00000602840.1
TCEB1
transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
chr14_+_70346125 0.07 ENST00000361956.3
ENST00000381280.4
SMOC1
SPARC related modular calcium binding 1
chr17_-_5372271 0.07 ENST00000225296.3
DHX33
DEAH (Asp-Glu-Ala-His) box polypeptide 33
chr16_+_66400533 0.07 ENST00000341529.3
CDH5
cadherin 5, type 2 (vascular endothelium)
chr11_-_62752429 0.07 ENST00000377871.3
SLC22A6
solute carrier family 22 (organic anion transporter), member 6
chrX_-_128977781 0.07 ENST00000357166.6
ZDHHC9
zinc finger, DHHC-type containing 9

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB7A_ZBTB7C

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.5 GO:1903410 lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410)
0.3 0.8 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.2 1.2 GO:0044861 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281) positive regulation of potassium ion import(GO:1903288)
0.2 0.7 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.2 0.6 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.2 0.5 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.1 0.4 GO:0034959 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.1 0.7 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 0.2 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
0.1 0.2 GO:0097254 renal tubular secretion(GO:0097254)
0.1 0.4 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.1 0.2 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.1 0.2 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.1 0.3 GO:0006850 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.1 0.3 GO:0090669 telomerase RNA stabilization(GO:0090669)
0.1 0.2 GO:0072268 specification of loop of Henle identity(GO:0072086) pattern specification involved in metanephros development(GO:0072268)
0.1 0.2 GO:1903936 response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.1 0.4 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.2 GO:0030860 regulation of polarized epithelial cell differentiation(GO:0030860)
0.0 0.7 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.4 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.2 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.0 0.1 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.0 0.2 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.2 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.1 GO:0061183 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129) dermatome development(GO:0061054) regulation of dermatome development(GO:0061183) renal vesicle induction(GO:0072034)
0.0 0.1 GO:1905064 negative regulation of vascular smooth muscle cell differentiation(GO:1905064)
0.0 0.2 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.0 0.6 GO:0021894 cerebral cortex GABAergic interneuron development(GO:0021894)
0.0 0.2 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.4 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.1 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 0.1 GO:0000255 allantoin metabolic process(GO:0000255)
0.0 0.2 GO:0001757 somite specification(GO:0001757)
0.0 0.4 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.5 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0 0.1 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.0 0.5 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.0 0.2 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.0 0.4 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.1 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.0 0.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 0.1 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 0.1 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.0 2.3 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.0 0.3 GO:0015732 prostaglandin transport(GO:0015732)
0.0 0.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 1.5 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.0 0.1 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
0.0 0.1 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.0 GO:0072054 renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054) inner medullary collecting duct development(GO:0072061)
0.0 0.2 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.4 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.7 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.0 0.6 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.1 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.2 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.0 GO:0007412 axon target recognition(GO:0007412)
0.0 0.3 GO:0071108 protein K48-linked deubiquitination(GO:0071108)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0043260 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260)
0.1 0.4 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.1 0.5 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.3 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.1 1.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.3 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.7 GO:0033010 paranodal junction(GO:0033010)
0.0 0.2 GO:1990742 microvesicle(GO:1990742)
0.0 0.2 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.2 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.3 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.4 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.1 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.1 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.3 GO:0031045 dense core granule(GO:0031045)
0.0 1.8 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.5 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.9 GO:0002102 podosome(GO:0002102)
0.0 0.2 GO:0097227 sperm annulus(GO:0097227)
0.0 0.3 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.5 GO:0005289 high-affinity basic amino acid transmembrane transporter activity(GO:0005287) high-affinity arginine transmembrane transporter activity(GO:0005289) high-affinity lysine transmembrane transporter activity(GO:0005292)
0.1 2.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 0.4 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.2 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
0.1 1.2 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.1 GO:0032427 GBD domain binding(GO:0032427)
0.0 0.8 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.5 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.3 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.5 GO:0015926 glucosidase activity(GO:0015926)
0.0 0.5 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.3 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.1 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.0 0.2 GO:0070363 mitochondrial light strand promoter sense binding(GO:0070363)
0.0 0.4 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.2 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 1.1 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.3 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.1 GO:1902444 riboflavin binding(GO:1902444)
0.0 0.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 1.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.2 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.0 0.1 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0 0.1 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.2 GO:0015288 porin activity(GO:0015288)
0.0 0.3 GO:0008061 chitin binding(GO:0008061)
0.0 0.2 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.3 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.6 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.2 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.0 GO:0099609 microtubule lateral binding(GO:0099609)
0.0 0.1 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.2 GO:0032183 SUMO binding(GO:0032183)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.7 GO:0000049 tRNA binding(GO:0000049)
0.0 0.3 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.8 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.6 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.1 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.2 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 2.3 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.5 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0 0.7 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.3 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.4 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres