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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for ZIC1

Z-value: 0.60

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Transcription factors associated with ZIC1

Gene Symbol Gene ID Gene Info
ENSG00000152977.5 Zic family member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZIC1hg19_v2_chr3_+_147127142_147127171-0.331.0e-01Click!

Activity profile of ZIC1 motif

Sorted Z-values of ZIC1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr21_+_46020497 3.04 ENST00000380102.2
keratin associated protein 10-7
chr21_-_46012386 2.29 ENST00000400368.1
keratin associated protein 10-6
chr1_+_61869748 1.84 ENST00000357977.5
nuclear factor I/A
chr4_-_186733363 1.59 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
sorbin and SH3 domain containing 2
chr14_+_38677123 1.33 ENST00000267377.2
somatostatin receptor 1
chr11_-_2160180 1.30 ENST00000381406.4
insulin-like growth factor 2 (somatomedin A)
chr6_+_132891461 1.27 ENST00000275198.1
trace amine associated receptor 6
chr17_+_40913210 1.23 ENST00000253796.5
receptor (G protein-coupled) activity modifying protein 2
chr10_-_33623826 1.05 ENST00000374867.2
neuropilin 1
chr4_-_7105056 0.98 ENST00000504402.1
ENST00000499242.2
ENST00000501888.2
RP11-367J11.3
chr10_-_33623564 0.87 ENST00000374875.1
ENST00000374822.4
neuropilin 1
chr12_-_59314246 0.81 ENST00000320743.3
leucine-rich repeats and immunoglobulin-like domains 3
chr1_+_65775204 0.79 ENST00000371069.4
DnaJ (Hsp40) homolog, subfamily C, member 6
chr11_-_134123142 0.78 ENST00000392595.2
ENST00000341541.3
ENST00000352327.5
ENST00000392594.3
thymocyte nuclear protein 1
chr7_+_150264365 0.76 ENST00000255945.2
ENST00000461940.1
GTPase, IMAP family member 4
chr13_-_29069232 0.74 ENST00000282397.4
ENST00000541932.1
ENST00000539099.1
fms-related tyrosine kinase 1
chr11_+_66824346 0.73 ENST00000532559.1
ras homolog family member D
chr19_-_11450249 0.73 ENST00000222120.3
RAB3D, member RAS oncogene family
chr17_-_18945798 0.69 ENST00000395635.1
GRB2-related adaptor protein
chrX_+_77166172 0.68 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATPase, Cu++ transporting, alpha polypeptide
chr6_-_146285221 0.65 ENST00000367503.3
ENST00000438092.2
ENST00000275233.7
SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase
chr22_+_29702572 0.65 ENST00000407647.2
ENST00000416823.1
ENST00000428622.1
growth arrest-specific 2 like 1
chr17_+_60704762 0.63 ENST00000303375.5
mannose receptor, C type 2
chr1_-_94586651 0.62 ENST00000535735.1
ENST00000370225.3
ATP-binding cassette, sub-family A (ABC1), member 4
chr17_-_67057047 0.62 ENST00000495634.1
ENST00000453985.2
ENST00000585714.1
ATP-binding cassette, sub-family A (ABC1), member 9
chr12_-_15038779 0.60 ENST00000228938.5
ENST00000539261.1
matrix Gla protein
chr17_-_67057114 0.60 ENST00000370732.2
ATP-binding cassette, sub-family A (ABC1), member 9
chr3_+_50192499 0.58 ENST00000413852.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr9_-_127263265 0.58 ENST00000373587.3
nuclear receptor subfamily 5, group A, member 1
chr10_-_33624002 0.58 ENST00000432372.2
neuropilin 1
chr10_-_101945771 0.58 ENST00000370408.2
ENST00000407654.3
ER lipid raft associated 1
chr17_-_39183452 0.57 ENST00000361883.5
keratin associated protein 1-5
chr14_+_57735614 0.55 ENST00000261558.3
adaptor-related protein complex 5, mu 1 subunit
chr16_+_2521500 0.55 ENST00000293973.1
netrin 3
chr19_+_34287751 0.51 ENST00000590771.1
ENST00000589786.1
ENST00000284006.6
ENST00000588881.1
potassium channel tetramerization domain containing 15
chr3_+_148847371 0.51 ENST00000296051.2
ENST00000460120.1
Hermansky-Pudlak syndrome 3
chr11_-_74022658 0.50 ENST00000427714.2
ENST00000331597.4
prolyl 4-hydroxylase, alpha polypeptide III
chr11_+_66824276 0.50 ENST00000308831.2
ras homolog family member D
chr11_-_73309228 0.50 ENST00000356467.4
ENST00000064778.4
family with sequence similarity 168, member A
chr21_+_46117087 0.49 ENST00000400365.3
keratin associated protein 10-12
chr18_-_52989217 0.49 ENST00000570287.2
transcription factor 4
chr17_-_67057203 0.48 ENST00000340001.4
ATP-binding cassette, sub-family A (ABC1), member 9
chr18_-_52989525 0.48 ENST00000457482.3
transcription factor 4
chr8_-_120685608 0.47 ENST00000427067.2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr21_-_39870339 0.45 ENST00000429727.2
ENST00000398905.1
ENST00000398907.1
ENST00000453032.2
ENST00000288319.7
v-ets avian erythroblastosis virus E26 oncogene homolog
chrX_+_24711997 0.45 ENST00000379068.3
ENST00000379059.3
polymerase (DNA directed), alpha 1, catalytic subunit
chr12_+_13197218 0.44 ENST00000197268.8
KIAA1467
chr4_-_7941596 0.42 ENST00000420658.1
ENST00000358461.2
actin filament associated protein 1
chr16_+_28858004 0.40 ENST00000322610.8
SH2B adaptor protein 1
chr9_-_16870704 0.40 ENST00000380672.4
ENST00000380667.2
ENST00000380666.2
ENST00000486514.1
basonuclin 2
chr14_+_36295638 0.40 ENST00000543183.1
breast cancer metastasis-suppressor 1-like
chr19_-_46142637 0.38 ENST00000590043.1
ENST00000589876.1
echinoderm microtubule associated protein like 2
chr16_-_2379688 0.38 ENST00000567910.1
ATP-binding cassette, sub-family A (ABC1), member 3
chr10_+_49917751 0.36 ENST00000325239.5
ENST00000413659.2
WDFY family member 4
chr1_-_60392452 0.36 ENST00000371204.3
cytochrome P450, family 2, subfamily J, polypeptide 2
chr17_-_53809473 0.36 ENST00000575734.1
transmembrane protein 100
chr19_+_45409011 0.35 ENST00000252486.4
ENST00000446996.1
ENST00000434152.1
apolipoprotein E
chr19_-_16582815 0.35 ENST00000455140.2
ENST00000248070.6
ENST00000594975.1
epidermal growth factor receptor pathway substrate 15-like 1
chr1_+_95699704 0.34 ENST00000370202.4
RWD domain containing 3
chr17_-_39191107 0.33 ENST00000344363.5
keratin associated protein 1-3
chr22_+_44319648 0.32 ENST00000423180.2
patatin-like phospholipase domain containing 3
chr11_+_64002292 0.32 ENST00000426086.2
vascular endothelial growth factor B
chr8_-_82754427 0.31 ENST00000353788.4
ENST00000520618.1
ENST00000518183.1
ENST00000396330.2
ENST00000519119.1
ENST00000345957.4
sorting nexin 16
chr17_+_18280976 0.31 ENST00000399134.4
envoplakin-like
chr1_+_95699740 0.31 ENST00000429514.2
ENST00000263893.6
RWD domain containing 3
chr22_+_44319619 0.30 ENST00000216180.3
patatin-like phospholipase domain containing 3
chr1_+_1567474 0.30 ENST00000356026.5
matrix metallopeptidase 23B
chr1_+_100315613 0.30 ENST00000361915.3
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chr16_+_30996502 0.29 ENST00000353250.5
ENST00000262520.6
ENST00000297679.5
ENST00000562932.1
ENST00000574447.1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr1_+_100316041 0.29 ENST00000370165.3
ENST00000370163.3
ENST00000294724.4
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chr2_-_99552620 0.29 ENST00000428096.1
ENST00000397899.2
ENST00000420294.1
KIAA1211-like
chr1_+_1567546 0.29 ENST00000378675.3
matrix metallopeptidase 23B
chr11_-_2193025 0.28 ENST00000333684.5
ENST00000381178.1
ENST00000381175.1
ENST00000352909.3
tyrosine hydroxylase
chr14_+_36295504 0.27 ENST00000216807.7
breast cancer metastasis-suppressor 1-like
chr1_+_161087873 0.27 ENST00000368009.2
ENST00000368007.4
ENST00000368008.1
ENST00000392190.5
nitrilase 1
chr19_-_58609570 0.26 ENST00000600845.1
ENST00000240727.6
ENST00000600897.1
ENST00000421612.2
ENST00000601063.1
ENST00000601144.1
zinc finger and SCAN domain containing 18
chr2_+_120189422 0.26 ENST00000306406.4
transmembrane protein 37
chr21_+_18811205 0.26 ENST00000440664.1
chromosome 21 open reading frame 37
chr2_+_169926047 0.26 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
dehydrogenase/reductase (SDR family) member 9
chr7_-_102789629 0.25 ENST00000417955.1
ENST00000341533.4
ENST00000425379.1
N-acyl phosphatidylethanolamine phospholipase D
chr1_+_93544821 0.25 ENST00000370303.4
metal response element binding transcription factor 2
chrX_-_153979315 0.25 ENST00000369575.3
ENST00000369568.4
ENST00000424127.2
GRB2-associated binding protein 3
chr12_-_25801478 0.25 ENST00000540106.1
ENST00000445693.1
ENST00000545543.1
ENST00000542224.1
intermediate filament tail domain containing 1
chr1_+_93544791 0.25 ENST00000545708.1
ENST00000540243.1
ENST00000370298.4
metal response element binding transcription factor 2
chr5_+_140514782 0.25 ENST00000231134.5
protocadherin beta 5
chr17_+_37894570 0.25 ENST00000394211.3
growth factor receptor-bound protein 7
chr12_+_27091426 0.24 ENST00000546072.1
ENST00000327214.5
FGFR1 oncogene partner 2
chr4_-_89444883 0.24 ENST00000273968.4
PIGY upstream reading frame
chr11_+_64001962 0.24 ENST00000309422.2
vascular endothelial growth factor B
chr12_+_27091316 0.24 ENST00000229395.3
FGFR1 oncogene partner 2
chr21_-_31864275 0.24 ENST00000334063.4
keratin associated protein 19-3
chr13_-_100624012 0.24 ENST00000267294.4
Zic family member 5
chr11_+_67071050 0.23 ENST00000376757.5
slingshot protein phosphatase 3
chr12_-_27091183 0.23 ENST00000544548.1
ENST00000261191.7
ENST00000537336.1
asunder spermatogenesis regulator
chrX_+_46771848 0.22 ENST00000218343.4
jade family PHD finger 3
chrX_+_46771711 0.22 ENST00000424392.1
ENST00000397189.1
jade family PHD finger 3
chrX_-_78622805 0.22 ENST00000373298.2
integral membrane protein 2A
chr15_-_71407806 0.22 ENST00000566432.1
ENST00000567117.1
cancer/testis antigen 62
chr19_-_6433765 0.22 ENST00000321510.6
solute carrier family 25, member 41
chr19_+_35940486 0.21 ENST00000246549.2
free fatty acid receptor 2
chr2_-_46769694 0.20 ENST00000522587.1
ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2
chr16_+_838614 0.20 ENST00000262315.9
ENST00000455171.2
CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
chr15_-_71407833 0.20 ENST00000449977.2
cancer/testis antigen 62
chr9_+_35792151 0.20 ENST00000342694.2
natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
chr12_-_11036844 0.20 ENST00000428168.2
proline-rich protein HaeIII subfamily 1
chrX_-_129299847 0.19 ENST00000319908.3
ENST00000287295.3
apoptosis-inducing factor, mitochondrion-associated, 1
chr11_+_120207787 0.19 ENST00000397843.2
ENST00000356641.3
Rho guanine nucleotide exchange factor (GEF) 12
chr1_-_177134024 0.19 ENST00000367654.3
astrotactin 1
chr6_-_168720382 0.19 ENST00000610183.1
ENST00000607983.1
ENST00000366795.3
dishevelled-binding antagonist of beta-catenin 2
chr19_+_13135731 0.19 ENST00000587260.1
nuclear factor I/X (CCAAT-binding transcription factor)
chr14_-_50999190 0.19 ENST00000557390.1
mitogen-activated protein kinase kinase kinase kinase 5
chr1_+_16348497 0.19 ENST00000439316.2
chloride channel, voltage-sensitive Ka
chr17_-_76274572 0.18 ENST00000374945.1
RP11-219G17.4
chr1_-_244615425 0.18 ENST00000366535.3
adenylosuccinate synthase
chr1_+_22962948 0.18 ENST00000374642.3
complement component 1, q subcomponent, A chain
chr8_+_85097110 0.17 ENST00000517638.1
ENST00000522647.1
RALY RNA binding protein-like
chr6_+_31949801 0.17 ENST00000428956.2
ENST00000498271.1
complement component 4A (Rodgers blood group)
chr16_+_771663 0.16 ENST00000568916.1
family with sequence similarity 173, member A
chr19_-_46142680 0.16 ENST00000245925.3
echinoderm microtubule associated protein like 2
chr19_-_2740036 0.16 ENST00000586572.1
ENST00000269740.4
Uncharacterized protein
solute carrier family 39 (zinc transporter), member 3
chr5_+_64920543 0.15 ENST00000399438.3
ENST00000510585.2
trafficking protein particle complex 13
CDNA FLJ26957 fis, clone SLV00486; Uncharacterized protein
chr17_-_3796334 0.15 ENST00000381771.2
ENST00000348335.2
ENST00000158166.5
calcium/calmodulin-dependent protein kinase kinase 1, alpha
chr4_-_66536196 0.15 ENST00000511294.1
EPH receptor A5
chrX_-_129299638 0.14 ENST00000535724.1
ENST00000346424.2
apoptosis-inducing factor, mitochondrion-associated, 1
chr15_+_80351910 0.14 ENST00000261749.6
ENST00000561060.1
zinc finger, AN1-type domain 6
chr15_+_77712993 0.14 ENST00000336216.4
ENST00000381714.3
ENST00000558651.1
high mobility group 20A
chr4_-_66536057 0.14 ENST00000273854.3
EPH receptor A5
chr2_-_74780176 0.14 ENST00000409549.1
lysyl oxidase-like 3
chr1_+_16370271 0.13 ENST00000375679.4
chloride channel, voltage-sensitive Kb
chr5_-_64920115 0.13 ENST00000381018.3
ENST00000274327.7
tripartite motif containing 23
chr6_-_34216766 0.13 ENST00000481533.1
ENST00000468145.1
ENST00000413013.2
ENST00000394990.4
ENST00000335352.3
chromosome 6 open reading frame 1
chr19_+_37095719 0.12 ENST00000423582.1
zinc finger protein 382
chr21_+_31768348 0.12 ENST00000355459.2
keratin associated protein 13-1
chr10_+_21823079 0.11 ENST00000377100.3
ENST00000377072.3
ENST00000446906.2
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr1_+_22963158 0.10 ENST00000438241.1
complement component 1, q subcomponent, A chain
chr2_-_29297127 0.10 ENST00000331664.5
chromosome 2 open reading frame 71
chrX_+_72064690 0.10 ENST00000438696.1
DMRT-like family C1B
chr14_+_22739823 0.10 ENST00000390464.2
T cell receptor alpha variable 38-1
chr19_+_42364460 0.10 ENST00000593863.1
ribosomal protein S19
chr6_+_28109703 0.10 ENST00000457389.2
ENST00000330236.6
zinc finger with KRAB and SCAN domains 8
chr1_+_207039154 0.09 ENST00000367096.3
ENST00000391930.2
interleukin 20
chr1_+_18958008 0.09 ENST00000420770.2
ENST00000400661.3
paired box 7
chr1_+_89990431 0.09 ENST00000330947.2
ENST00000358200.4
leucine rich repeat containing 8 family, member B
chr11_+_15095108 0.08 ENST00000324229.6
ENST00000533448.1
calcitonin-related polypeptide beta
chr1_-_71513471 0.08 ENST00000370931.3
ENST00000356595.4
ENST00000306666.5
ENST00000370932.2
ENST00000351052.5
ENST00000414819.1
ENST00000370924.4
prostaglandin E receptor 3 (subtype EP3)
chr19_+_54024251 0.08 ENST00000253144.9
zinc finger protein 331
chr3_+_141105705 0.08 ENST00000513258.1
zinc finger and BTB domain containing 38
chr1_+_62417957 0.07 ENST00000307297.7
ENST00000543708.1
InaD-like (Drosophila)
chrX_+_18725758 0.07 ENST00000472826.1
ENST00000544635.1
ENST00000496075.2
protein phosphatase, EF-hand calcium binding domain 1
chr19_-_50168962 0.07 ENST00000599223.1
ENST00000593922.1
ENST00000600022.1
ENST00000596765.1
ENST00000599144.1
ENST00000596822.1
ENST00000598108.1
ENST00000601373.1
ENST00000595034.1
ENST00000601291.1
interferon regulatory factor 3
chr6_-_168476511 0.06 ENST00000440994.2
FERM domain containing 1
chr4_-_66535653 0.06 ENST00000354839.4
ENST00000432638.2
EPH receptor A5
chr1_+_16348366 0.06 ENST00000375692.1
ENST00000420078.1
chloride channel, voltage-sensitive Ka
chr19_-_14586125 0.06 ENST00000292513.3
prostaglandin E receptor 1 (subtype EP1), 42kDa
chr5_-_126409159 0.06 ENST00000607731.1
ENST00000535381.1
ENST00000296662.5
ENST00000509733.3
chromosome 5 open reading frame 63
chr16_-_31100284 0.06 ENST00000280606.6
protease, serine, 53
chr2_+_11679963 0.06 ENST00000263834.5
growth regulation by estrogen in breast cancer 1
chr1_-_43833628 0.05 ENST00000413844.2
ENST00000372458.3
ELOVL fatty acid elongase 1
chr9_-_35103105 0.05 ENST00000452248.2
ENST00000356493.5
stomatin (EPB72)-like 2
chr10_+_21823243 0.05 ENST00000307729.7
ENST00000377091.2
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr17_+_75450075 0.05 ENST00000592951.1
septin 9
chr20_+_61924532 0.05 ENST00000358894.6
ENST00000326996.6
ENST00000435874.1
collagen, type XX, alpha 1
chr7_+_107384579 0.05 ENST00000222597.2
ENST00000415884.2
Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
chr18_+_61420169 0.05 ENST00000425392.1
ENST00000336429.2
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr11_+_63606558 0.05 ENST00000350490.7
ENST00000502399.3
MAP/microtubule affinity-regulating kinase 2
chr6_-_35656685 0.04 ENST00000539068.1
ENST00000540787.1
FK506 binding protein 5
chr17_-_9940058 0.04 ENST00000585266.1
growth arrest-specific 7
chr1_-_211307315 0.04 ENST00000271751.4
potassium voltage-gated channel, subfamily H (eag-related), member 1
chr15_+_73976715 0.04 ENST00000558689.1
ENST00000560786.2
ENST00000561213.1
ENST00000563584.1
ENST00000561416.1
CD276 molecule
chr6_+_31730773 0.04 ENST00000415669.2
ENST00000425424.1
suppressor APC domain containing 1
chr11_+_63606477 0.03 ENST00000508192.1
ENST00000361128.5
MAP/microtubule affinity-regulating kinase 2
chr19_-_50169064 0.03 ENST00000593337.1
ENST00000598808.1
ENST00000600453.1
ENST00000593818.1
ENST00000597198.1
ENST00000601809.1
ENST00000377139.3
interferon regulatory factor 3
chr11_-_57417405 0.03 ENST00000524669.1
ENST00000300022.3
yippee-like 4 (Drosophila)
chr13_+_102104952 0.03 ENST00000376180.3
integrin, beta-like 1 (with EGF-like repeat domains)
chr17_-_62208169 0.03 ENST00000606895.1
endoplasmic reticulum to nucleus signaling 1
chr2_+_234668894 0.02 ENST00000305208.5
ENST00000608383.1
ENST00000360418.3
UDP glucuronosyltransferase 1 family, polypeptide A1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr3_-_71803474 0.02 ENST00000448225.1
ENST00000496214.2
eukaryotic translation initiation factor 4E family member 3
chr17_-_4464081 0.02 ENST00000574154.1
gamma-glutamyltransferase 6
chr11_-_59612969 0.02 ENST00000541311.1
ENST00000257248.2
gastric intrinsic factor (vitamin B synthesis)
chr6_+_41755389 0.01 ENST00000398884.3
ENST00000398881.3
translocase of outer mitochondrial membrane 6 homolog (yeast)
chr11_-_110582773 0.01 ENST00000524756.1
Rho GTPase activating protein 20
chr22_-_23922448 0.01 ENST00000438703.1
ENST00000330377.2
immunoglobulin lambda-like polypeptide 1
chr4_+_66536248 0.00 ENST00000514260.1
ENST00000507117.1
RP11-807H7.1
chr2_+_79347577 0.00 ENST00000233735.1
regenerating islet-derived 1 alpha
chr4_+_2627159 0.00 ENST00000382839.3
ENST00000324666.5
ENST00000545951.1
ENST00000502458.1
ENST00000505311.1
family with sequence similarity 193, member A
chr18_+_76829385 0.00 ENST00000426216.2
ENST00000307671.7
ENST00000586672.1
ENST00000586722.1
ATPase, class II, type 9B
chr2_+_232457569 0.00 ENST00000313965.2
chromosome 2 open reading frame 57
chr11_+_63606373 0.00 ENST00000402010.2
ENST00000315032.8
ENST00000377809.4
ENST00000413835.2
ENST00000377810.3
MAP/microtubule affinity-regulating kinase 2

Network of associatons between targets according to the STRING database.

First level regulatory network of ZIC1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.5 GO:0060301 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.3 1.3 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.2 0.7 GO:0071284 cellular response to lead ion(GO:0071284)
0.2 0.7 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.2 0.6 GO:0035290 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.2 0.8 GO:0032474 otolith morphogenesis(GO:0032474)
0.1 0.7 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.1 1.3 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 0.6 GO:0007538 primary sex determination(GO:0007538)
0.1 1.2 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 0.9 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 0.4 GO:0006272 leading strand elongation(GO:0006272)
0.1 0.3 GO:0052314 terpene metabolic process(GO:0042214) phytoalexin metabolic process(GO:0052314)
0.1 0.8 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 0.5 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 0.5 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.1 0.2 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.1 1.8 GO:0072189 ureter development(GO:0072189)
0.1 0.2 GO:0072061 inner medullary collecting duct development(GO:0072061) negative regulation of nodal signaling pathway(GO:1900108)
0.1 0.6 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.1 0.1 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.1 0.6 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.1 0.3 GO:0035900 response to isolation stress(GO:0035900)
0.0 0.2 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.3 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650) response to aldosterone(GO:1904044)
0.0 0.1 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 0.5 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 1.6 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.2 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 0.3 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.4 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.0 0.7 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0 0.2 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.5 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.3 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.2 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 5.6 GO:0031424 keratinization(GO:0031424)
0.0 0.1 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
0.0 1.2 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.0 0.6 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.5 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.4 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.0 0.4 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.5 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.1 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.0 0.2 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.2 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.2 GO:0015866 ADP transport(GO:0015866)
0.0 0.5 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.4 GO:0003416 endochondral bone growth(GO:0003416)
0.0 0.0 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.1 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.5 GO:0097443 sorting endosome(GO:0097443)
0.2 1.2 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.2 0.5 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 0.4 GO:0097232 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.1 0.4 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.1 6.2 GO:0045095 keratin filament(GO:0045095)
0.1 0.4 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 0.3 GO:0005602 complement component C1 complex(GO:0005602)
0.0 0.3 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.7 GO:0042588 zymogen granule(GO:0042588)
0.0 0.2 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.6 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.7 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 1.9 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.3 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.7 GO:0000786 nucleosome(GO:0000786)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0004994 somatostatin receptor activity(GO:0004994)
0.2 2.5 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.2 0.7 GO:0032767 copper-dependent protein binding(GO:0032767)
0.2 1.3 GO:0001594 trace-amine receptor activity(GO:0001594)
0.2 1.2 GO:0097643 amylin receptor activity(GO:0097643)
0.1 0.7 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.5 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.1 0.6 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.4 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.1 0.6 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 1.0 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.5 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1 0.6 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.1 1.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.2 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.1 0.3 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 0.3 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
0.0 0.6 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.3 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 1.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.7 GO:0031489 myosin V binding(GO:0031489)
0.0 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.3 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.3 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.2 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.2 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.4 GO:0070330 aromatase activity(GO:0070330)
0.0 0.0 GO:0045518 interleukin-22 receptor binding(GO:0045518)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.2 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 2.0 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 0.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.8 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.5 PID HNF3A PATHWAY FOXA1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.8 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 2.1 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 1.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.4 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 1.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.6 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 1.1 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.6 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.8 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.2 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.5 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 1.3 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)